UCD CLINICAL RESEARCH CENTRE - University College Dublin Clinical... · UCD Clinical Research Centre Strategic Priorities 2015 - 2019 2 1 1 UCD Clinical Research Centre Strategic

UCD CLINICAL RESEARCH CENTRESTRATEGIC PRIORITIES 2015 - 2019

UCD School of Medicine and Medical Science

CONTENTS

1: STRATEGIC CONTEXT 1

2: MISSION & VISION 5

3: OPERATIONAL STRUCTURE 9

4: CLINICAL RESEARCH 11

5: EDUCATION & TRAINING 16

UCD Clinical Research Centre Strategic Priorities 2015 - 2019 2

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1 UCD Clinical Research Centre Strategic Priorities 2015 - 2019 UCD Clinical Research Centre Strategic Priorities 2015 - 2018 2

STRATEGIC CONTEXTThe UCD Clinical Research Centre is an academic-led, multi-site, patient-focused resource supporting clinical and translational research. It operates under a single integrated governance structure within the UCD School of Medicine & Medical Science. It has been created to deliver one of the University’s strategic objectives of advancing high quality, impactful clinical and translational research. The centre is also responsible for delivering high quality education programmes to serve future academic and industry staffing needs. The UCD Clinical Research Centre has two modern purpose-built facilities, at the Mater Misericordiae University Hospital and at St Vincent’s University Hospital. Together, these two hospitals serve the healthcare needs of approximately 1 million people in the Dublin area and act as local, regional and national referral centres for a host of clinical specialties. With the creation of the Ireland East Hospital Group (IEHG) (which comprises eleven hospitals in the East Leinster region), the UCD Clinical Research Centre will expand to provide the same research supports across the region, to deliver the benefits of participation in clinical and translation research to our patients. The UCD Clinical Research Centre is at the core of the UCD/IEHG Academic Health Sciences research and innovation strategy and will provide a focal point for collaborative, multidisciplinary patient-focused research. The centre links the clinical community to core university research institutes including the UCD Conway Institute, Systems Biology Ireland, the UCD Charles Institute of Dermatology and ARCH. Our reputation for implementing complex clinical research programmes across multiple sites to the highest ethical, regulatory and scientific standards positions the UCD CRC ideally to enable and drive a wider academic health sciences collaboration.

STRATEGIC CONTEXT

Our vision will be delivered by meeting the following major strategic objectives:

Build on the success to date of the UCD ClinicalResearch Centre at MMUH and SVUH

Expand the activity across the Ireland EastHospital Group

Become a leading centre for graduate education in clinical and translational research

Support UCD and IEHG ambition to be a leadingEuropean academic-led acute hospital network

Ensure that our patients have rapid access to thebest available treatments and that novelinterventions are developed and that these aresuccessfully implemented in routine healthcarepractice

Maintain a diversified income stream for the UCDClinical Research Centre through an appropriatelevel of clinical trial, investigator-led studies,laboratory services and educational activity

STRATEGIC OBJECTIVES


STRATEGIC CONTEXT

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VISIONOur vision is of an internationally recognised centre of clinical and translational research excellence which will develop the next generation of clinician scientists.

UCD Clinical Research Centre Strategic Priorities 2015 - 2019 6 5 UCD Clinical Research Centre Strategic Priorities 2015 - 2019

VISION &

MISSION

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Our mission is to improve the health of the nation by ensuring that novel interventions are developed, evaluated and implemented in routine clinical practice.MISSION


VISION &

MISSION

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CRC MANAGEMENT TEAM

CRC STRATEGIC ADVISORY BOARD

HEAD OF SCHOOL MEDICINE AND MEDICAL SCIENCE

OPERATIONAL STRUCTURE

SCIENTIFIC LABORATORY

SERVICES

CLINICAL RESEARCH

EDUCATION

& TRAININGHOSPITAL GROUP

INTEGRATION


OPERATIONAL STRU

CTURE

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SUPPORTING EXCELLENCE IN TRANSLATIONAL RESEARCH

In the first five years of its operations, the UCD Clinical Research Centre has assisted 67 principal investigators with 160 clinical research projects comprising over 32,000 patient contacts.We have developed a comprehensive physical infrastructure and implemented externally audited procedures. We have retained a cohort of 12 professional staff who are available to investigators on an ‘as required’ basis, minimising the cost of investigations and maximizing the effectiveness and impact of the investigators’ research funding. The deployment of the resource across several projects ensures that experience gained in one study can benefit research led by other investigators.

The UCD Clinical Research Centre will build on its strong track record to date to further enhance clinical and translational research activity across the wider IEHG Network. Specifically we will:

Support University and Hospital research priority domains as required

Enable investigators to leverage additional grant income, in particular targeting EU Horizon 2020 programmes and major national funding schemes

Further develop and expand biobank infrastructure at current and new sites

Strengthen industry partnerships in clinical and translational research

Expand core biomarker validation laboratory



4CLIN

ICAL RESEARCH

CURRENT POSITION

To date, we have supported clinical trial activity across 10 hospitals. Our current study portfolio includes 36 industry sponsored clinical trials (19 phase II, 15 phase III, 2 phase IV), 10 investigator-initiated clinical trials and 38 translational and observational research studies. These studies now account for an average of 5,300 patient contacts per annum.

Create a dedicated clinical trials team, who will complete and manage both commercial and investigator initiated clinical trials

Make key appointments in quality and regulatory affairs, business development, research pharmacy, research nursing and data management

Provide training in clinical trials for all staff members, including ICH-GCP and manage network-wide training records

Develop enhanced site management capabilities in conjunction with external partners

Enhance the investigator initiated clinical trial activity within the network by supporting all stages of trial roll out

Develop a plan for the establishment of a dedicated clinical pharmacology unit, including business case development, staffing plans and oversight

Support Investigators to leverage additional clinical trial income through the Health Research Board’s dedicated clinical trial funding schemes



CLINICAL RESEARCH

ENHANCING PATIENT CARE BY LEADING CLINICAL TRIALS 4

CURRENT POSITION

The UCD Clinical Research Centre has developed a number of training programmes in clinical research and the conduct of clinical trials. These programmes capitalise on existing expertise and activity within the UCD Clinical Research Centre and include

» Graduate Certificate in Clinical Research » Graduate Certificate / Graduate Diploma /

MSc in Clinical and Translational Research » UCD-SZU Joint MSc in Clinical and

Translational ResearchThere are a number of tangible benefits to our participation in education and training activity:

» Provides specialist expertise from industry partners

» Demonstrates expertise available within the UCD Clinical Research Centre

» Diversifies revenue stream » Builds strong relationships with CRO’s

TRAINING THE INVESTIGATORS OF THE FUTURE

Position UCD as Ireland’s leading provider of clinical research training and establish an international profile as the preferred destination for students

Underpin the UCD-Shenzhen University Specialised International College by providing a dedicated training programme in clinical and translational research

Enhance the appeal of UCD and Ireland East Hospital Group as a destination for medical trainees by offering an MD programme which aims to develop the next generation of clinician investigators

Foster strong corporate partnerships by developing tailored CPD programmes for the clinical research, pharma and biotech industries

CURRENT POSITION STRATEGIC OBJECTIVES


EDU

CATION &

TRAININ

G

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The creation of both the Ireland East Hospital Group and the UCD College of Health Sciences has provided further growth opportunities for of the UCD Clinical Research Centre. We have already played a major role in expanding the research network through:

» Support for Carlow / Kilkenny eHealth project

» Creation of core General Practice Research group

» First protocol for general practice currently being finalised for REC submission

» Significant progress in developing National Healthcare Impacts platform

» Roll out of investigator initiated clinical trial to regional hospital sites

» Support for National Maternity Hospital, Holles Street to undertake first investigator initiated clinical trials

» Coordination of successful first round bids to HRB Clinical Trial Networks programme

CREATING AN ACADEMIC HEALTH SCIENCES NETWORK

CURRENT POSITION

Facilitate strong relationships between the UCD College of Health Sciences and its clinical partners

Develop and implement integrated multidisciplinary teaching programmes, where required.

Support the objectives of the Ireland East Hospital group bya. Driving professional development, b. Enhancing IEHG as a destination for trainees

andc. Underpinning the development of a vibrant

research endeavour, from campus to hospital to community

Play a leading role in the establishment of the National Clinical Research Framework



EDU

CATION &

TRAININ

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Credits

Photograph: St. Vincents Hospital Nutley Wing

Concept Architect: Scott Tallon Walker, Executive Architect: Keogan Architects in association with Keppie Design, Photography: Donal Murphy

UCD CLINICAL RESEARCH CENTRE

WWW.UCD.IE/MEDICINE

T: +353 1 716 4587 E: [email protected]

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UCD CLINICAL RESEARCH CENTRE - University College Dublin Clinical... · UCD Clinical Research Centre Strategic Priorities 2015 - 2019 2 1 1 UCD Clinical Research Centre Strategic