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Quantitative MRCP MKT066 - 3.0 [email protected] | www.perspectum.com | US: (+1) 857 321 8675 | UK: (+44) 1865 655325 Accurate assessment of the biliary system is essential in diagnosis and monitoring of hepatobiliary diseases such as PSC, PBC, and CCA. It is also integral to liver transplant preparation and post-transplant evaluation. Magnetic resonance cholangiopancreatography pancreatobiliary (MRCP) is used extensively in the evaluation of biliary tree anatomy. It non-invasively provides information that increases diagnostic confidence. However, MRCP is not quantitative and has high subjectivity in reading. Traditional MRCP MRCP+ Analysis Figure 2: MRCP+ duct analysis in 3D Figure 1: MRCP image processed by MRCP+ Next Generation: MRCP+ Figure 3: Bile duct unfolded in 2D with measured diameter MRCP+ enables point-wise computation of bile duct diameters, enabling automatic identification and quantification of candidate strictures and dilatations. Key Benefits of MRCP+ Quantitative analysis of the biliary tree and pancreatic duct. Non-invasive and no contrast agent needed. Can use historic MRCP images. Requires no additional hardware, reducing capital expenditure. MRCP+ is a quantitative pancreatobiliary imaging tool which uses computational techniques to enhance MRCP images. Combining true 3D rendering of the enhanced data with quantitative characterization facilitates clear mapping of the biliary tree and pancreatic duct. Non-invasive quantitative assessment of pancreatobiliary tract (Figure 1) and individual ducts (Figures 2 and 3) may be used for assessment of the overall pancreatobiliary tract health and detection and monitoring of changes in duct widths.

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Quantitative MRCP

MKT066 - 3.0

[email protected] | www.perspectum.com | US: (+1) 857 321 8675 | UK: (+44) 1865 [email protected] | www.perspectum.com | US: (+1) 857 321 8675 | UK: (+44) 1865 655325

Accurate assessment of the biliary system is essential in diagnosis and monitoring of hepatobiliary diseases such as PSC, PBC, and CCA. It is also integral to liver transplant preparation and post-transplant evaluation.

Magnetic resonance cholangiopancreatography pancreatobiliary (MRCP) is used extensively in the evaluation of biliary tree anatomy. It non-invasively provides information that increases diagnostic confidence. However, MRCP is not quantitative and has high subjectivity in reading.

Traditional MRCP MRCP+ Analysis

Figure 2: MRCP+ duct analysis in 3D

Figure 1: MRCP image processed by MRCP+

Next Generation: MRCP+

Figure 3: Bile duct unfolded in 2D with measured diameter

MRCP+ enables point-wise computation of bile duct diameters, enabling automatic identification and quantification of candidate strictures and dilatations.

Key Benefits of MRCP+

Quantitative analysis of the biliary tree and pancreatic duct.

Non-invasive and no contrast agent needed.

Can use historic MRCP images.

Requires no additional hardware, reducing capital expenditure.

MRCP+ is a quantitative pancreatobiliary imaging tool which uses computational techniques to enhance MRCP images. Combining true 3D rendering of the enhanced data with quantitative characterization facilitates clear mapping of the biliary tree and pancreatic duct.

Non-invasive quantitative assessment of pancreatobiliary tract (Figure 1) and individual ducts (Figures 2 and 3) may be used for assessment of the overall pancreatobiliary tract health and detection and monitoring of changes in duct widths.

Quantitative MRCP

MKT066 - 3.0

[email protected] | www.perspectum.com | US: (+1) 857 321 8675 | UK: (+44) 1865 655325

Quantitative 3D Modeling

Case Studies Using MRCP+

Pediatric patient with biliary atresia and bile lakes

MRCP+ has been FDA 510(k) cleared and CE marked for the quantitative evaluation of biliary structures.

2D views from traditional MRCP Quantitative 3D MRCP+ modeling

Patient with PSCHealthy volunteer

The MRCP+ image (left) shows two bile lakes formed on the left side and one bile lake in the lower right of the liver. The absence of signal in the middle signifies a tumor, which was surgically removed.

Although the bile lakes on the left side were drained, the one on the right went undetected.

MRCP+ enabled visualization of the right bile lake and a second procedure to drain it was performed.