-
Carotid Plaque Volume measured by Tomographic 3D Ultrasound
Mr Steven K Rogers,Senior Clinical Vascular Scientist
University of Manchester & MFT NHS FT
-
Speaker name: Mr Steven Rogers
..........................................................................................
I have the following potential conflicts of interest to
report:
Consulting
Employment in industry
Stockholder of a healthcare company
Owner of a healthcare company
Other(s)
I do not have any potential conflict of interest
Disclosure
Munich Vascular Conference (MAC) 2018 2
-
Asymptomatic carotid surgery trial (ACST) N=3,120 follow-up 5
years
Munich Vascular Conference (MAC) 2018 3
ipsilateral stroke
CEA 2.7 0.5
medical 9.5 0.9
Difference 6.8%95% CI 4.8-8.8
p
-
Munich Vascular Conference (MAC) 2018 4
Carotid Plaque Remodels
-
Munich Vascular Conference (MAC) 2018 5
Carotid Plaque Volume
CPV = Wt / D
-
Munich Vascular Conference (MAC) 2018 6
Carotid Plaque VolumeN=339
1.0
1.5
0.0
0.5
cm3
asymptomaticn=69
p
-
Munich Vascular Conference (MAC) 2018 7
Carotid Plaque VolumeN=339
Ball & Rogers et al, BJS (2018); 105:262-269.
ns
Asymptomatic
69
Asymptomatic
CPV cm3P
-
Munich Vascular Conference (MAC) 2018 8
Carotid Plaque VolumeN=270
Ball & Rogers et al, BJS (2018); 105:262-269.
CPV cm3
-
Munich Vascular Conference (MAC) 2018 9
Tomographic 3D ultrasound (tUS)N=200
-
Munich Vascular Conference (MAC) 2018 10
Tomographic 3D Ultrasound (tUS)N=200
-
Munich Vascular Conference (MAC) 2018 11
Image Fusion
-
Munich Vascular Conference (MAC) 2018 12
CPV measured by tUSN=56
7 asymptomatic
7 female
Median stenosis 60 – 69%
B-mode
CEUS
Fused
-
0 1 2 3 40
1
2
3
4
U S E R 1
U S E R 2
Munich Vascular Conference (MAC) 2018 13
tUS Intra-observer (cm3)N=56
r=0.96p
-
0 . 0 0 . 5 1 . 0 1 . 5 2 . 0 2 . 5 3 . 00 . 0
0 . 5
1 . 0
1 . 5
2 . 0
2 . 5
3 . 0
3 . 5
U S E R 1
U S E R 2
Munich Vascular Conference (MAC) 2018 14
tUS Inter-observer (cm3)N=56
r=0.93p
-
Munich Vascular Conference (MAC) 2018 15
CEA vs tUS CPV’s (cm3)N=56
B-modebias=-0.18±0.32 cm3r=0.87P
-
Munich Vascular Conference (MAC) 2018 16
Acknowledgement:This project has received funding from the
European Union’s Horizon 2020 researchand innovation programme
under grant agreement No [760380].
Carotid Plaque Volume (CPV)
Relates to cerebral ischemia symptoms
Accurately measured in patients by tUS
?Does CPV predict stroke?
Carotid Plaque Volume measured by Tomographic 3D
Ultrasound�DisclosureAsymptomatic carotid surgery trial (ACST)
�N=3,120 follow-up 5 yearsCarotid Plaque RemodelsCarotid Plaque
VolumeCarotid Plaque Volume�N=339Carotid Plaque Volume�N=339Carotid
Plaque Volume�N=270Tomographic 3D ultrasound (tUS)�N=200Tomographic
3D Ultrasound (tUS)�N=200Image FusionCPV measured by tUS�N=56tUS
Intra-observer (cm3)�N=56tUS Inter-observer (cm3)�N=56CEA vs tUS
CPV’s (cm3)�N=56Foliennummer 16
