For Research Use Only. Not for use in diagnostic procedures.

PR7000-0132© Agilent Technologies, Inc. 2016Printed in USA, February 25, 20165991-5942EN

CALL OR LEARN MORE AT:1-800-227-9770 | www.agilent.com/genomics/V6

To request more information or get a demo, call your Agilent Sales Representative.SureSelectXT Human All Exon V6

SureSelectXT Human All Exon V6+UTRSureSelectXT Human All Exon V6+COSMICSureSelectXT Human All Exon V6 Plus 1SureSelectXT Human All Exon V6 Plus 2SureSelectXT2 Human All Exon V6SureSelectXT2 Human All Exon V6+UTRSureSelectXT2 Human All Exon V6+COSMICSureSelectXT2 Human All Exon V6 Plus 1SureSelectXT2 Human All Exon V6 Plus 2

5190-88635190-88815190-93075190-88665190-88695190-88725190-88845190-93105190-88755190-8878

16 rxn

5190-88645190-88825190-93085190-88675190-88705190-88735190-88855190-93115190-88765190-8879

96 rxn

5190-88655190-88835190-93095190-88685190-88715190-88745190-93065190-93125190-88775190-8880

96 rxn autoProduct Description

This comprehensive high performing exome is part of Agilent’s NGS Constitutional Disease Research Solutions. Together, we can accelerate discoveries and advance clinical research.

The SureSelect Human All Exon V6

Adoption of exome sequencing is rapidly increasing in both clinical and translational research, allowing for simultaneous analysis of protein coding regions of the genome.

The SureSelect Human All Exon V6 is a high performing design that targets updated content, including challenging regions, from the databases relevant to both the clinical and translational researchers.

Most comprehensive content, an exome solution for every applicationMost up-to-date content including challenging regions. Easily add UTRs for translational research, COSMIC for cancer research or custom content for specific applications

Deep and complete target coverage for answersHighly optimized and uniform design for increased breadth and depth of target coverage

Complete and flexible solutions from sample to dataCompatible with efficient SureSelect workflows with the fastest hybridization times, with solutions for design, sample QC, automation and data analysis

The SureSelect Human All Exon V6Optimized bait selection and boosting enables highly uniform coverage of the exome and each individual targeted exon helping address the drop off in coverage at the edges of targets, maximizing variant information output for per exome sequenced.

The SureSelect Human All Exon V6

SureSelect Human All Exon V6

60Mb

99%

99%

99%

99%

99%

YES

66Mb

99%

99%

99%

99%

99%

96%

YES

37Mb

98%

99%

98%

NO

SureSelect Human All Exon V6+COSMIC

Competitor I

64Mb

99%

99%

99%

YES

Competitor N

Target Size

RefSeq

CCDS

GENCODe

HGMD cds

OMIN cds

COSMIC

Customization

100%

90%

80%

70%

60%

50%

40%

30%

20%

10%

0%% bases at 1x

% bases at 10x

% bases at 20x

% bases at 30x

150x 100x

Deep coverage of 56 key regions in constitutional research for complete and accurate variant calling

% DATABASES COVERED

Adoption of exome sequencing is rapidly increasing in both clinical and translational research, allowing for simultaneous analysis of protein coding regions of the genome.

The SureSelect Human All Exon V6 is a high performing design that targets updated content, including challenging regions, from the databases relevant to both the clinical and translational researchers.

Most comprehensive content, an exome solution for every applicationMost up-to-date content including challenging regions. Easily add UTRs for translational research, COSMIC for cancer research or custom content for specific applications

Deep and complete target coverage for answersHighly optimized and uniform design for increased breadth and depth of target coverage

Complete and flexible solutions from sample to dataCompatible with efficient SureSelect workflows with the fastest hybridization times, with solutions for design, sample QC, automation and data analysis

The SureSelect Human All Exon V6Optimized bait selection and boosting enables highly uniform coverage of the exome and each individual targeted exon helping address the drop off in coverage at the edges of targets, maximizing variant information output for per exome sequenced.

The SureSelect Human All Exon V6

SureSelect Human All Exon V6

60Mb

99%

99%

99%

99%

99%

YES

66Mb

99%

99%

99%

99%

99%

96%

YES

37Mb

98%

99%

98%

NO

SureSelect Human All Exon V6+COSMIC

Competitor I

64Mb

99%

99%

99%

YES

Competitor N

Target Size

RefSeq

CCDS

GENCODe

HGMD cds

OMIN cds

COSMIC

Customization

100%

90%

80%

70%

60%

50%

40%

30%

20%

10%

0%% bases at 1x

% bases at 10x

% bases at 20x

% bases at 30x

150x 100x

Deep coverage of 56 key regions in constitutional research for complete and accurate variant calling

% DATABASES COVERED

For Research Use Only. Not for use in diagnostic procedures.

PR7000-0132© Agilent Technologies, Inc. 2016Printed in USA, February 25, 20165991-5942EN

CALL OR LEARN MORE AT:1-800-227-9770 | www.agilent.com/genomics/V6

To request more information or get a demo, call your Agilent Sales Representative.SureSelectXT Human All Exon V6

SureSelectXT Human All Exon V6+UTRSureSelectXT Human All Exon V6+COSMICSureSelectXT Human All Exon V6 Plus 1SureSelectXT Human All Exon V6 Plus 2SureSelectXT2 Human All Exon V6SureSelectXT2 Human All Exon V6+UTRSureSelectXT2 Human All Exon V6+COSMICSureSelectXT2 Human All Exon V6 Plus 1SureSelectXT2 Human All Exon V6 Plus 2

5190-88635190-88815190-93075190-88665190-88695190-88725190-88845190-93105190-88755190-8878

16 rxn

5190-88645190-88825190-93085190-88675190-88705190-88735190-88855190-93115190-88765190-8879

96 rxn

5190-88655190-88835190-93095190-88685190-88715190-88745190-93065190-93125190-88775190-8880

96 rxn autoProduct Description

This comprehensive high performing exome is part of Agilent’s NGS Constitutional Disease Research Solutions. Together, we can accelerate discoveries and advance clinical research.

The SureSelect Human All Exon V6