prev
next
out of 138

The Role of Neutrophils in Severe Asthma

Embed Size (px)

Citation preview

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    1/138

    mailto:[email protected]://network.bepress.com/hgg/discipline/947?utm_source=digitalcommons.mcmaster.ca%2Fopendissertations%2F7237&utm_medium=PDF&utm_campaign=PDFCoverPageshttp://network.bepress.com/hgg/discipline/958?utm_source=digitalcommons.mcmaster.ca%2Fopendissertations%2F7237&utm_medium=PDF&utm_campaign=PDFCoverPageshttp://digitalcommons.mcmaster.ca/opendissertations?utm_source=digitalcommons.mcmaster.ca%2Fopendissertations%2F7237&utm_medium=PDF&utm_campaign=PDFCoverPageshttp://digitalcommons.mcmaster.ca/open_diss?utm_source=digitalcommons.mcmaster.ca%2Fopendissertations%2F7237&utm_medium=PDF&utm_campaign=PDFCoverPageshttp://digitalcommons.mcmaster.ca/opendissertations?utm_source=digitalcommons.mcmaster.ca%2Fopendissertations%2F7237&utm_medium=PDF&utm_campaign=PDFCoverPageshttp://digitalcommons.mcmaster.ca/?utm_source=digitalcommons.mcmaster.ca%2Fopendissertations%2F7237&utm_medium=PDF&utm_campaign=PDFCoverPages

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    2/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    3/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    4/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    5/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    6/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    7/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    8/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    9/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    10/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    11/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    12/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    13/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    14/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    15/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    16/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    17/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    18/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    19/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    20/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    21/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    22/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    23/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    24/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    25/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    26/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    27/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    28/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    29/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    30/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    31/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    32/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    33/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    34/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    35/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    36/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    37/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    38/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    39/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    40/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    41/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    42/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    43/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    44/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    45/138

    http://journals2.scholarsportal.info.libaccess.lib.mcmaster.ca/search-advanced.xqy?q=A.%20Druilhe&field=AU

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    46/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    47/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    48/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    49/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    50/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    51/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    52/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    53/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    54/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    55/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    56/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    57/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    58/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    59/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    60/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    61/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    62/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    63/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    64/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    65/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    66/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    67/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    68/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    69/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    70/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    71/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    72/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    73/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    74/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    75/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    76/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    77/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    78/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    79/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    80/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    81/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    82/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    83/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    84/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    85/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    86/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    87/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    88/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    89/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    90/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    91/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    92/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    93/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    94/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    95/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    96/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    97/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    98/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    99/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    100/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    101/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    102/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    103/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    104/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    105/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    106/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    107/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    108/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    109/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    110/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    111/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    112/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    113/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    114/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    115/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    116/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    117/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    118/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    119/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    120/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    121/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    122/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    123/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    124/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    125/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    126/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    127/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    128/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    129/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    130/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    131/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    132/138

    http://www.ncbi.nlm.nih.gov/pubmed/12975579http://www.ncbi.nlm.nih.gov/pubmed?term=%22Pretolani%20M%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22L%C3%A9tuv%C3%A9%20S%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Druilhe%20A%22%5BAuthor%5D

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    133/138

    http://www.ncbi.nlm.nih.gov/pubmed/8004300http://www.ncbi.nlm.nih.gov/pubmed?term=%22Sur%20S%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Kita%20H%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Mansfield%20ES%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Weiler%20DA%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Ohnishi%20T%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Gleich%20GJ%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Hunt%20LW%22%5BAuthor%5D

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    134/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    135/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    136/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    137/138

  • 7/30/2019 The Role of Neutrophils in Severe Asthma

    138/138

    http://www.ncbi.nlm.nih.gov/pubmed/8666838http://www.ncbi.nlm.nih.gov/pubmed?term=%22Bolscher%20BG%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Verhoeven%20AJ%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Roos%20D%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22Weening%20RS%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22van%20Zwieten%20R%22%5BAuthor%5Dhttp://www.ncbi.nlm.nih.gov/pubmed?term=%22van%20Pelt%20LJ%22%5BAuthor%5D

Anti-IgE treatment in severe asthma

Anti-IgE treatment in severe asthma

Documents
Acute severe asthma picu management

Acute severe asthma picu management

Health & Medicine
Intravenous magnesium sulfate therapy in severe asthma

Intravenous magnesium sulfate therapy in severe asthma

Documents
A Charter to Improve Patient Care in Severe Asthma€¦ · Severe asthma is a subtype of asthma that is difficult to treat and control. By conservative estimates, severe asthma affects

A Charter to Improve Patient Care in Severe Asthma€¦ · Severe asthma is a subtype of asthma that is difficult to treat and control. By conservative estimates, severe asthma affects

Documents
ASTHMA MANAGEMENT INFORMATION · a severe asthma flare-up, however they may also be included in a child’s asthma action plan for those children diagnosed with severe asthma. These

ASTHMA MANAGEMENT INFORMATION · a severe asthma flare-up, however they may also be included in a child’s asthma action plan for those children diagnosed with severe asthma. These

Documents
Severe asthma-cpg-erj

Severe asthma-cpg-erj

Documents
Treatment Options for Complicated/Severe Asthmakallergy.com/wp-content/uploads/2018/04/Asthma... · Biologics For Severe Persistent Asthma •Omalizumab(Xolair): •Severe Allergic

Treatment Options for Complicated/Severe Asthmakallergy.com/wp-content/uploads/2018/04/Asthma... · Biologics For Severe Persistent Asthma •Omalizumab(Xolair): •Severe Allergic

Documents
Bronchial Thermoplasty For Severe Persistent Asthma

Bronchial Thermoplasty For Severe Persistent Asthma

Documents
Severe asthma

Severe asthma

Health & Medicine
GINA DIFFICULT-TO-TREAT & SEVERE ASTHMA · Difficult- to-treat asthma. Does : Severe asthma. IGD MAIA D N DII

GINA DIFFICULT-TO-TREAT & SEVERE ASTHMA · Difficult- to-treat asthma. Does : Severe asthma. IGD MAIA D N DII

Documents
Severe Intractable Asthma - Denver, Colorado · Severe Intractable Asthma Disclosure None Lecture Objectives 1. Define asthma and severe asthma in children. 2. Identify alternate

Severe Intractable Asthma - Denver, Colorado · Severe Intractable Asthma Disclosure None Lecture Objectives 1. Define asthma and severe asthma in children. 2. Identify alternate

Documents
Severe Asthma pdf for Series - National Jewish HealthEpidemiology of Severe Asthma • About 5‐15% of asthma patients have severe disease, not controlled by available therapies

Severe Asthma pdf for Series - National Jewish HealthEpidemiology of Severe Asthma • About 5‐15% of asthma patients have severe disease, not controlled by available therapies

Documents
Management of severe asthma

Management of severe asthma

Documents
RSAR Registry Protocol 13479 · BA – Bronchial asthma RSAR – Russian severe asthma registry SA - severe bronchial asthma GINA - Global Initiative for asthma (Global Strategy for

RSAR Registry Protocol 13479 · BA – Bronchial asthma RSAR – Russian severe asthma registry SA - severe bronchial asthma GINA - Global Initiative for asthma (Global Strategy for

Documents
Severe Allergic Asthma Beyond Borders - MTSmts.org.my/.../Expert_Sharing_on_Severe_Allergic_Asthma.pdf · 2020. 9. 17. · Severe Allergic Asthma Beyond Borders. Dr Azza Omar Consultant

Severe Allergic Asthma Beyond Borders - MTSmts.org.my/.../Expert_Sharing_on_Severe_Allergic_Asthma.pdf · 2020. 9. 17. · Severe Allergic Asthma Beyond Borders. Dr Azza Omar Consultant

Documents
Journal of Pulmonology (Severe Asthma)

Journal of Pulmonology (Severe Asthma)

Documents
Severe asthma management

Severe asthma management

Health & Medicine
Severe asthma Pathophysiology and treatment

Severe asthma Pathophysiology and treatment

Documents
Severe asthma: Advances in current management and future ... · Asthma: Current status and future directions Severe asthma: Advances in current management and future therapy Peter

Severe asthma: Advances in current management and future ... · Asthma: Current status and future directions Severe asthma: Advances in current management and future therapy Peter

Documents
Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma … · 2017-01-05 · Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry

Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma … · 2017-01-05 · Heterogeneity of phenotypes in severe asthmatics. The Belgian Severe Asthma Registry

Documents
Asthma - Suli Pharma · Risk factors for Severe acute asthma include 1- A history of previous severe asthma exacerbation ( e.g. hospitalizations, intubations, or hypoxic seizures)

Asthma - Suli Pharma · Risk factors for Severe acute asthma include 1- A history of previous severe asthma exacerbation ( e.g. hospitalizations, intubations, or hypoxic seizures)

Documents
Asthma Exacerbations -Assessment and Management of Severe Asthma in Adults in Hospital

Asthma Exacerbations -Assessment and Management of Severe Asthma in Adults in Hospital

Documents
Intra-epithelial Neutrophils in Paediatric Severe Asthma ... · T D ACCEPTED MANUSCRIPT 1 1 Intra-epithelial Neutrophils in Paediatric Severe Asthma are Associated with 2 Better Lung

Intra-epithelial Neutrophils in Paediatric Severe Asthma ... · T D ACCEPTED MANUSCRIPT 1 1 Intra-epithelial Neutrophils in Paediatric Severe Asthma are Associated with 2 Better Lung

Documents
Severe acute asthma in children

Severe acute asthma in children

Health & Medicine
Novel approaches for Severe refractory asthma

Novel approaches for Severe refractory asthma

Documents
Evidence based Management of acute severe asthma

Evidence based Management of acute severe asthma

Health & Medicine
Severe asthma Severe asthma: the unmet need and the global challenge It is easy to take for granted the simplicity and ease of breathing but for people with severe asthma the struggle

Severe asthma Severe asthma: the unmet need and the global challenge It is easy to take for granted the simplicity and ease of breathing but for people with severe asthma the struggle

Documents
Acute Severe Asthma in Children 2

Acute Severe Asthma in Children 2

Documents
Current Practice - Acute Severe Asthma

Current Practice - Acute Severe Asthma

Documents
THE ROLE OF NEUTROPHILS IN SEVERE ASTHMA · 2014-06-18 · role of neutrophils in severe asthma in patients on optimum steroid doses with controlled eosinophilic airway inflammation

THE ROLE OF NEUTROPHILS IN SEVERE ASTHMA · 2014-06-18 · role of neutrophils in severe asthma in patients on optimum steroid doses with controlled eosinophilic airway inflammation

Documents