Contents

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Plenary Session 1

PS1-1 All-Oral Dual Therapy With Daclatasvir and Asunaprevir in Patients in Korea and Taiwan With HCV Genotype 1b Infection ······························ 3J-H. Kao, C-Y. Peng, T-T. Chang, J. Heo, C-J. Chu, Y-J. Lee, C-C. Lin, K.T. Yoon, S-Y. Han, J-W. Lee, J-H. Yoon, Y.S. Kim, H-J. Lee, Y.S. Lim, S.W. Paik, W-Y. Tak, J.H. Kwon, M. Linaberry, S. Noviello, A. Torbeyns, E. Hughes, S.H. Ahn

PS1-2 Predictors of Clinical Response: Results from a Large, Randomized Controlled Study with TDF plus PEG-IFN Combination for Chronic Hepatitis B···························································································································································································································· 3

Sang Hoon Ahn, Won Young Tak, Yoon Jun Kim, Young Kul Jung, Kwan Sik Lee, Jeong Heo, Si Hyun Bae, So Young Kwon, June Sung Lee, Young-Suk Lim, Seong Gyu Hwang, Soon Koo Baik, Hong Soo Kim, Nam Ik Han, Kwan Soo Byun, Lanjia Lin, Philip Dinh, Eduardo B. Martins, Patrick Marcellin

PS1-3 Nucleos(t)ide Analogues against Hepatitis B Virus Reduces the Risk of Various Major Malignancies: A Nationwide Cohort Study Based on the Health Insurance Review and Assessment Service Database ··········································································································································· 4Dong Hyeon Lee, Jeong-Hoon Lee, Yuri Cho, Jung-Ju Yoo, Minjong Lee, Young Youn Cho, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

PS1-4 Hepatitis B Virus Reactivation in HBsAg-negative and Anti- HBc-positive Korean Patients with Hematologic Malignancy ··································· 4Ji Won Han, Soonkyu Lee, Hyun Yang, Hae Lim Lee, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

PS1-5 98% SVR12 in Korean and Taiwanese Patients with Chronic GT1 HCV-infection Receiving 12-weeks of Ledipasvir/Sofosbuvir: A Phase 3 Study···························································································································································································································· 5

Young-Suk Lim, Sang Hoon Ahn, Seung-Woon Paik, Youn-Jae Lee, Sook-Hyang Jeong, Ju-Hyun Kim, Kwan-Sik Lee, Hyung-Joon Yim, Seung-Kew Yoon, Won-Young Tak, Jia-Horng Kao, Wan-Long Chuang, Jenny C. Yang, Hongmei Mo, Bing Gao, Steven J. Knox, Phillip S. Pang, Sang-Young Han, Jeong Heo, Young-Seok Kim, Kwan-Soo Byun, Yoon-Jun Kim, Kwang-Hyub Han

PS1-6 Simeprevir plus Peginterferon/Ribavirin in Treatment-naïve East Asian Patients with HCV Genotype 1 Infection: Results from the Phase III TIGER Study···························································································································································································································· 5

J. Heo, L. Wei, JH Kim, KY Yoon, KS Lee, SH Um, YJ Lee, DJ Kim, SH Ahn, SK Yoon, JH Yoon, JH Shim, SW Paik, KS Byun, D Lee, R. Kalmeijer, S. Ouwerkerk-Mahadevan, O. Lenz, R. Sinha, M. Li, J. Scott, M. Peeters, J. Witek

Plenary Session 2

PS2-1 Differences in Prevalence, Mortality, and Patient Characteristics of Acute-on-Chronic Liver Failure Defined by APASL ACLF Research Consortium vs. EASL-CLIF Consortium ··················································································································································································· 9Do Seon Song, Tae Yeob Kim, Hee Yeon Kim, Dong Hyun Sinn, Eileen L. Yoon, Chang Wook Kim, Young Kul Jung, Ki Tae Suk, Sang Soo Lee, Chang Hyeong Lee, Tae Hun Kim, Jeong Han Kim, Won Hyeok Choe, Hyung Joon Yim, Sung Eun Kim, Soon Koo Baik, Byung Seok Lee, Jae Young Jang, Jeong Ill Suh, Hyoung Su Kim, Seong Woo Nam, Hyeok Choon Kwon, Young Seok Kim, Hee Bok Chae, Jin Mo Yang, Joo Hyun Sohn, Heon Ju Lee, Seung Ha Park, Byung Hoon Han, Eun Hee Choi, Chang H. Kim, Dong Joon Kim, on behalf of the Korean Acute-on-Chronic Liver Failure (KACLiF) Study Group

PS2-2 Acute-on Chronic Liver Failure: Is This New Entity Unrelated with Underlying Liver Disease State? ····································································· 9Yoo Li Lim, Soon Koo Baik, Yoon Ok Jang, Sang Ok Kwon, Seung Hwan Cha, Young Ju Kim, Moon Young Kim

PS2-3 Scoring Systems Proposed for Acute-on-Chronic Liver Failure Accurately Predicts Short-term Mortality in Patients with Alcoholic Hepatitis ···· 10Hee Yeon Kim, Tae Yeob Kim, Chang Wook Kim, Do Seon Song, Dong Hyun Sinn, Eileen L Yoon, Young Kul Jung, Heon Ju Lee, Young Seok Kim, Sang Gyune Kim, Ki Tae Suk, Dong Joon Kim

PS2-4 Investigating Immunomodulatory Role of CX3CR1 Related with Differentiation and Functional Polarization of Kupffer Cells in Alcoholic Liver Disease·························································································································································································································· 10

Young-Sun Lee, Ji Hoon Kim, Won-hyo Suh, Yang Jae Yoo, Tae Suk Kim, Seong Hee Kang, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Won-il Jeong, Kwan Soo Byun

PS2-5 RAR-Related Orphan Receptor Gamma (RORC) is a Novel Modulator of TGF-beta Pathway During Epithelial Mesenchymal Transition (EMT) Progression in Liver Fibrosis ··············································································································································································· 11Sung Min Kim, Jung Eun Choi, Wonhee Hur, Jung-Hee Kim, Sung Woo Kim, Sung Woo Hong, Eun Byul Lee, Seung Kew Yoon

PS2-6 Prospective Comparison of Noninvasive Fibrosis Assessment to Predict Advanced Fibrosis or Cirrhosis in Patients with NAFLD ······················· 11Byung Ook Lee, Sae Kyung Joo, Byeong Gwan Kim, Yong Jin Jung, Hwi Young Kim, Seung Jin Yoo

Plenary Session 3

Multidisciplinary Approach to Liver Cancer

PS3-01 Evaluation of Early-stage Hepatocellular Carcinoma with Magnetic Resonance Imaging Using a Liver-Specific Contrast Agent and Improvement in Survival ·············································································································································································································· 15Hyung-Don Kim, Young-Suk Lim, Seungbong Han, Jihyun An, Gi-Ae Kim, So Yeon Kim, So Jung Lee, HyungJin Won, Jae Ho Byun

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PS3-02 The Validation of Hong Kong Liver Cancer Classification for Prediction of Survival in Patients with Hepatocellular Carcinoma in Korea: Direct Comparison with Barcelona Clinic Liver Cancer ················································································································································ 15Young-Sun Lee, Ji Hoon Kim, Hae Rim Kim, Yang Jae Yoo, Tae Suk Kim, Seong Hee Kang, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

PS3-03 The Pentose Phosphate Pathway (PPP) is a Novel Therapeutic Target for Hepatocellular Carcinoma (HCC) Treatment ····································· 15Ming-Jing Xu, Kit-Ho Lai, Pui-Wah Tse, David Kung-Chun Chiu, Hui-Yu Koh, Cheuk-Ting Law, Chun-Ming Wong, Carmen Chak-Lui Wong, Irene Oi-Lin Ng

PS3-04 Stratification Biomarkers for Individualized Molecular Targeted Therapy in HCC ······························································································ 16HJ Wang, JH Kwon, JY Park, GJ Kang, YS Kim, DS Kim, YH Moon

PS3-05 The Impact of Tumor Size on Long-term Survival Outcomes after Resection of Solitary Hepatocellular Carcinoma: Single- institution Experience with 2558 Patients ···································································································································································································· 16Shin Hwang, Young-Joo Lee, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Sung-Gyu Lee

PS3-06 Phase I/IIa Study of Adjuvant Immunotherapy with Tumor Antigen-pulsed Dendritic Cells in Patients with Hepatocellular Carcinoma ············· 17Jeong-Hoon Lee, Minjong Lee, Yoon Lee, Min Kyu Heo, Jae-Sung Song, Ki-Hwan Kim, Hyunah Lee, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Yong-Soo Bae, Yoon Jun Kim

Multidisciplinary Approach to Liver Transplantation

PS3-07 Macro-Vascular Invasion of Hepatocellular Carcinoma Is Not an Absolute Contraindication for Living Donor Liver Transplantation ················· 17Kwang-Woong Lee, Suk-Won Suh, Jaehong Jeong, Hyeyoung Kim, Nam-Joon Yi, Kyung-Suk Suh

PS3-08 Outcome of Treated Preoperative Acute Spontaneous Bacterial Peritonitis in Adult Orthotopic Liver Transplantation ······································ 18Seunghwan Lee, Wontae Cho, Byunggon Na, Chanwoo Joh, Nuri Lee, Gyuseong Choi, Choon Hyuck David Kwon, Jae-Won Joh

PS3-09 Occurrence and Risk Factors of Invasive Fungal Infection in Liver Transplantation Recipients (ORIGIN a multicenter study in Korea) ················ 18Sang Il Kim, Youn Jeong Kim, Gun Hyung Na, Jong Young Choi, Seung Kew Yoon, Yung Kyung Yoo, Dong Goo Kim, Myoung Soo Kim, Jae Geun Lee, Dong Jin Joo, Soon Il Kim, Yu Seun Kim, Sang-Oh Lee, Shin Hwang, Sung Gyu Lee

PS3-10 Anti-thymocyte Globulin for Steroid Resistant Acute Rejection after Liver Transplantation ··············································································· 19Jae Geun Lee, Juhan Lee, Seung Hwan Song, Jung Jun Lee, Myoung Soo Kim, Man Ki Ju, Gi Hong Choi, Jin Sub Choi, Soon Il Kim, Dong Jin Joo

PS3-11 Role of Endoscopic Screening for De Novo Gastric Cancer and Colorectal Cancer in Korean Liver Transplant Recipients ································· 19Dong-Hwan Jung, Shin Hwang, Gi-Won Song, Chul-Soo Ahn, Deok-Bog Moon, Ki-Hun Kim, Gil-Chun Park, Jaewon Choe, Sung-Gyu Lee

PS3-12 Combined Use of Magnetic Resonance Fat Quantification and Magnetic Resonance Elastography in Living Liver Donors: Can It Reduce the Need for Preoperative Liver Biopsy? ··········································································································································································· 19Jeong Hee Yoon, Jeong Min Lee, Kyung-Suk Suh, Kwan-Woong Lee, Nam-Joon Yi, Kyung Bun Lee, Joon Koo Han, Byung Ihn Choi

Free Paper Presentation

1. HCV

O-001 Ledipasvir/Sofosbuvir RBV is Safe and Efficacious in Decompensated and Post Liver Transplantation HCV-infected Patients: Preliminary Results of the Prospective SOLAR-2 Trial ··········································································································································································· 23Markus Peck-Radosavljevic, Michael Manns, Xavier Forns, Didier Samuel, Jill Denning, Sarah Arterburn, Theo Brandt-Sarif, Phillip S. Pang, John G. McHutchison, Edward Gane, David Mutimer

O-002 Cost-Effectiveness of One-Time Screening for HCV in South Korea ·················································································································· 23Do Young Kim, Kwang-Hyub Han, Byungyool Jun, Tae Hyun Kim, Sohee Park, Thomas Ward, Samantha Webster, Phil McEwan

O-003 All-Oral, Fixed-Dose-Combination Therapy with Daclatasvir/ Asunaprevir/Beclabuvir, ± Ribavirin, for Chronic HCV Genotype 1-Infected Patients With Compensated Cirrhosis: Unity-2 Phase 3 Results ··············································································································································· 23A.J. Muir, F. Poordad, J. Lalezari, G.J. Everson, G.J. Dore, P. Kwo, C. Hézode, P.J. Pockros, A. Tran, A. Ramji, R. Yang, E.A. Hughes, E.S. Swenson, P.D. Yin on behalf of the UNITY-2 Study Team

O-004 High SVR Rates Despite Multiple Negative Predictors in Genotype 1 Patients Receiving Ombitasvir/Paritaprevir/r, Dasabuvir with/ without Ribavirin for 12/24 Weeks ······························································································································································································· 24Nancy Reau, Michael W. Fried, Heiner Wedemeyer, Curtis Cooper, Moisés Diago, Antonio Craxi, Simone Strasser, Jean-Francois DuFour, Wangang Xie, Lois Larsen, Emily O. Dumas, David Bernstein

O-005 98% SVR12 in Korean and Taiwanese Patients with Chronic GT2 HCV-infection Receiving 12-weeks of Sofosbuvir Ribavirin: An International Phase 3 Study ·············································································································································································································· 24Sang Hoon Ahn, Young-Suk Lim, Youn-Jae Lee, Seung-Woon Paik, Sook-Hyang Jeong, Ju-Hyun Kim, Kwan-Sik Lee, Hyung-Joon Yim, Seung-Kew Yoon, Won-Young Tak, Jia-Horng Kao, Wan-Long Chuang, Jenny C. Yang, Hongmei Mo, Bing Gao, Steven J. Knox, Diana M. Brainard, Sang-Young Han, Jeong Heo, Young-Seok Kim, Kwan-Soo Byun, Yoon-Jun Kim, Kwang-Hyub Han

Contents

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O-006 Long-Term Follow-Up of Patients Treated with Daclatasvir- Based Regimens in Phase 2 and 3 Studies ···························································· 25K.R. Reddy, S. Pol, P.J. Thuluvath, H. Kumada, J. Toyota, K. Chayama, J. Levin, E. Lawitz, A. Gadano, W. Ghesquiere, G. Gerken, M. Brunetto, C.Y. Peng, M. Silva, S. Strasser, J. Heo, F. McPhee, Z. Liu, M. Linaberry, E.A. Hughes, S. Noviello

O-007 Treatment Pattern and Outcomes of Chronic Hepatitis C in South Korea ········································································································· 26Eun Sun Jang, Young Seok Kim, Kyung-Ah Kim, Youn Jae Lee, Woo Jin Chung, In Hee Kim, Byung Seok Lee, Sook-Hyang Jeong

O-008 GRIM19 as a Potential Modulator of Intracellular Lipid Accumulation in Hepatitis C Virus Infection ································································· 26Jung-Hee Kim, Eun Byul Lee, Pil Soo Sung, Sung Woo Kim, Wonhee Hur, Jung-Eun Choi, Eui-Cheol Shin, Seung Kew Yoon

2. Cell Biology / Molecular Biology

O-009 The Role of Kruppel-like Factor 10 Deletion in Diet Induced Nonalcoholic Steatohepatitis in Mice ··································································· 27Jung Il Lee, Hye Young Chang, Ja Kyung Kim, Kwan Sik Lee

O-010 Over-expression of HNF4 Attenuated Lipotoxicity in Non- alcoholic Fatty Liver Disease Model ······································································· 27Jai Sun Lee, Dae Won Jun, Hyeon Tae Kang, Ki Seok Jang, Chang Hong Lee, Jae Yoon Jeong, Joo hyun Sohn, Tae Yeob Kim, Ho Hyun Nam, Wook Jin Lee

O-011 Important Role of NLRP Inflammasome Activation in Patients with Chronic Viral Hepatitis and Nonalcoholic Fatty Liver Dsease ······················ 27Seong Hee Kang, Jong Eun Yeon, Young Sun Lee, Tae Suk Kim, Yang Jae Yoo, Sang Jun Suh, Young Kul Jung, Baek Hui Kim, Ji Hoon Kim, Hyung Joon Yim, Kwan Soo Byun

O-012 MAVS and IRF3 Dependent Chemokine Production by Acute Hepatitis A Infection ·························································································· 28Pil Soo Sung, Jeewon Lee, Woo Jin Chung, Shin Hwang, Eui-Cheol Shin

O-013 FoxP3 and PD-1 are Decreased Significantly During 1 Year Tenofovir Therapy in Chronic Hepatitis B. ······························································ 29Hyosun Cho, Chang Wook Kim, Ji Young Kim, Hyung Gyu Choi, Hee Yeon Kim, Jong Young Choi, Seung Kew Yoon

O-014 Ginsenoside Rg3 Inhibits Hepatitis C Virus Induced Aberrant Mitochondrial Dynamics: Antiviral Mechanism of Ginsenoside Rg3 ··················· 29Jae-Young Jang, Seong-Jun Kim, Soung Won Jeong, Sae Hwan Lee, Young Don Kim, Sang Gyune Kim, Gab Jin Cheon, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim

O-015 The Roles of Unphosphorylated-ISGF3 in HCV Infection and Interferon Responsiveness ··················································································· 29Pil Soo Sung, HyeonJoo Cheon, Chung Hwan Cho, Do Youn Park, Hyung-Il Seo, Su-Hyung Park, Seung Kew Yoon, George R. Stark, Eui-Cheol Shin

O-016 Suppression of Neurophilin-1 Attenuates Cellular Growth and Enhances Doxorubicin-induced Cell Death in Human HCC Cells ····················· 30Jeong-Ju Yoo, Jung-Hwan Yoon, Dong Hyeon Lee, Yuri Cho, Yun Bin Lee, Minjong Lee, Young Youn Cho, Won-mook Choi, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Chung Yong Kim, Hyo-Suk Lee

O-017 A Novel Adipose Derived Stem Cell Line from the Falciform Ligament of the Liver ··························································································· 31Sang Woo Lee, Seon Ok Min, Seon Young Bak, Kyung Sik Kim

3. Acute Liver Disease / Liver Failure / Liver Transplantation / Others]

O-018 Prognostic Factors of Acute-on-Chronic Liver Failure in Patients with Liver Cirrhosis: the Korean Acute-on-Chronic Liver Failure (KACLiF) Study·························································································································································································································· 31

Do Seon Song, Tae Yeob Kim, Dong Joon Kim, Hee Yeon Kim, Dong Hyun Sinn, Eileen L. Yoon, Chang Wook Kim, Young Kul Jung, Ki Tae Suk, Sang Soo Lee, Chang Hyeong Lee, Tae Hun Kim, Jeong Han Kim, Sung Eun Kim, Soon Koo Baik, Byung Seok Lee, Jae Young Jang, Jeong Ill Suh, Hyoung Su Kim, Seong Woo Nam, Hyeok Choon Kwon, Young Seok Kim, Jin Mo Yang, Joo Hyun Sohn, Heon Ju Lee, Seung Ha Park, Byung Hoon Han, Eun Hee Choi

O-019 The Usefulness of Simplified CLIF-SOFA and Hyponatremia for Predicting Mortality in Patients with Acute Decompensation and Chronic Liver Disease·························································································································································································································· 32

Young Kul Jung, Tae Yeob Kim, Do Seon Song, Dong Joon Kim, Hee Yeon Kim, Dong Hyun Sinn, Eileen L Yoon, Joo Hyun Sohn, Chang Wook Kim, Ki Tae Suk, Jin Mo Yang, Heon Ju Lee

O-020 Characterization of Acute-on-Chronic Liver Failure and Prediction of Mortality in Patients with Severe Alcoholic Hepatitis ····························· 32Hwi Young Kim, Sohee Oh, Sae Kyung Joo, Yong Jin Jung, Byeong Gwan Kim, Kook Lae Lee, Won Kim

O-021 Scaffold Using Mesenchymal Stem Cell Treatment Increased Survival on Acute Liver Failure Model ································································· 33Hyeon Tae Kang, Dae Won Jun, Jai Sun Lee, Kiseok Jang, Chang Hong Lee, Jae Yoon Jeong, Joo hyun Sohn, Ho Hyun Nam, Min Young Kim, Wook Jin Lee

O-022 Model to Predict Recurrence after Living Donor Liver Transplantation for Hepatocellular Carcinoma Beyond the Milan Criteria ······················ 33Yuri Cho, Jeong-Hoon Lee, Dong Hyeon Lee, Minjong Lee, Jeong-ju Yoo, Young Youn Cho, Su Jong Yu, Nam-Joon Yi, Kwang-Woong Lee, Seoung Hoon Kim, Jong Man Kim, Jae-Won Joh, Yoon Jun Kim, Kyung-Suk Suh, Jung-Hwan Yoon

O-023 A Nationwide Seroprevalence of IgG Antibody to Hepatitis A from 2010 to 2014 in Korea: age-, sex- and area-adjusted prevalence rates ···· 33Kyung-Ah Kim, Moran Ki, Anna Lee, Kyoung-Ryul Lee, Sook-Hyang Jeong

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O-024 Incidence and Clinical Features of Drug Induced Liver Injury among Government Tertiary Hospital Patients on Anti-koch’s Treatment ··········· 34Milben Malbog, Marichona Naval, Felix Domingo, Michael Chu

O-025 Analysis of the Liver Volumes of Korean Adults Using Dr. LiverTM ····················································································································· 34Jaedo Yang, Xiaopeng Yang, Mina Lee, Nahyun Lee, Baekhee Lee, Seunghyun Kim, Jihyun Kim, Hee Chul Yu, Baik Hwan Cho, Heecheon You

O-026 Clinical Characteristics and Courses of Liver Abscess Caused by Toxocara ········································································································ 34Kyung Ho Ha, Ga Young Kim, Min Geun Kim, Jung Eun Song, Seung Jun Lee, Eun Young Kim, Byung Seok Kim, Chang Hyeong Lee

4. Liver Cancer, Basic

O-027 Oxamic Acid Suppresses Hepatocellular Carcinoma through Amplification of ROS Production under Hypoxic Conditions ······························· 35Dong Hyeon Lee, Yuri Cho, Jung-Ju Yoo, Minjong Lee, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

O-028 Ribosomal Association Factor NACA Is Critical for ERK Activation and Mitotic Progression in Tumor Cells ······················································· 35Mi-Jin Lee, Goung Ran Yu, Hua Lee, Yun A Kim, Jun Zhang, Dae Ghon Kim

O-029 Targeting an Epigenetic Reader Reveals Novel Targets of Liver Cancer ············································································································· 35Seong Hwi Hong, Sung Kyung Choi, Jung Woo Eun, Suk Woo Nam, Jueng Soo You

O-030 Evolutionary Cancer Favored Engineered Vaccinia Virus Attenuates Metastatic Hepatocellular Carcinoma ······················································ 36So Young Yoo, Seo Young Bang, Su-Nam Jeong, Hyun Young Woo, Ki Tae Yoon, Mong Cho, Dae Hwan Kang, Tae Ho Hwang, Jeong Heo

O-031 Theranostics-based identification of Target Molecules for Diagnosis and Therapy in Hepatocellular Carcinoma and Cholangiocarcinoma ······ 36Mi-Jin Lee, Goung-Ran Yu, Hua Lee, Yun-A Kim, Jun Zhang, Dae-Ghon Kim

O-032 Novel Genomic Marker for Predicting Prognosis in Patients with Hepatocellular Carcinoma Detected by Integration Analysis of Copy Number Alterations and Gene Expression Profile ···························································································································································· 37Hyo Jung Cho, Soon Sun Kim, Ju Han Park, Choong Kyun Noh, Sung Won Cho, Jae Youn Cheong

O-033 SLC15A2 Genomic Variation Is Associated with the Extraordinary Response of Sorafenib Treatment: Whole-genome Analysis in Patients with Hepatocellular Carcinoma ················································································································································································· 37Bo Hyun Kim, Yeon-Su Lee, Byung Chul Kim, Aesun Shin, Jin Sook Kim, Seung-Hyun Hong, Jung Ah Hwang, Jung Ahn Lee, Seungyoon Nam, Sung Hoon Lee, Jong Bhak, Joong-Won Park

O-034 Activation of YAP-1 by C-Myc Pathway is a Therapeutic Target in Hepatocellular Carcinoma Under Hypoxic Condition ·································· 37Yuri Cho, Dong Hyeon Lee, Eun Ju Cho, Minjong Lee, Jeong-ju Yoo, Young Youn Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon

O-035 Hypoxia Induces Myeloid-derived Suppressor Cell (MDSCs) Recruitment to Hepatocellular Carcinoma via CCL26/CX3CR1 ····························· 38David Kung-Chun Chiu, Iris Ming-Jing Xu, Robin Kit-Ho Lai, Aki Pui-Wah Tse, Larry Lai Wei, Hui-Yu Koh, Regina Cheuk-Lam Lo, Chun-Ming Wong, Irene Oi-Lin Ng, Carmen Chak-Lui Wong

5. Liver Cancer, Clinical (I)

O-036 Prediction Model for the Development of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B in the Era of Antiviral Treatment ···· 38Jem Ma Ahn, Yeon Seok Seo, Tae Hyung Kim, Sun Young Yim, Young Kul Jung, Ji Hoon Kim, Hyunggin An, Hyung Joon Yim, Hong Eun Yeon, Kwan Soo Byun, Soon Ho Um

O-037 Risk Assessment of Hepatocellular Carcinoma in Chronic Hepatitis B Patients with Long-term Antiviral Therapy ············································· 39Kyu Sik Jung, Do Young Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Hye Jin Ku, Kwang-Hyub Han, Sang Hoon Ahn

O-038 Anti-platelet Therapy Reduces the Incidence of Hepatocellular Carcinoma in Patients with Chronic Hepatitis B ··············································· 39Minjong Lee, Jeong-Hoon Lee, Sohee Oh, Hongkeun Ahn, Haeki Cho, Young Youn Cho, Jeong-Ju Yoo, Yuri Cho, Dong Hyeon Lee, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

O-039 Increasing Incidence of and Mortality by Hepatocellular Carcinoma and Decreasing Mortality by Liver Diseases in Korea: Nationwide Whole Population Data Analyses ···································································································································································································· 39Jihyun An, Young-Suk Lim, Yongjun Chang, Namkug Kim

O-040 Hepatocellular Carcinoma in the Absence of Cirrhosis: An Etiology-based Clinicopathological Study ······························································· 40Chang Woo Shim, Joong-Won Park, Bo Hyun Kim, Chang-Min Kim, Eun Kyung Hong

O-041 Long-term Outcomes of Hepatocellular Carcinoma after Curative Resection in Patients with Cirrhotic versus Non-cirrhotic Backgrounds ······· 40Hye Won Lee, Do Young Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Kwang-Hyub Han

O-042 Overexpression of Periostin is Related to Poor Prognosis of Hepatocellular Carcinoma ····················································································· 40Se Young Jang, Yu Rim Lee, Sun Kyung Jang, Suhyun Lee, Won Young Tak, Young Oh Kweon, Soo Young Park

O-043 Expression Profile of Glypican-3 in Hepatocellular Carcinoma with Clinical Correlation ···················································································· 41Yejoo Jeon, Haeryoung Kim, Eun Sun Jang, Sukho Hong, Jin-Wook Kim, Yoo-Seok Yoon, Jai Young Cho, Ho-Seong Han, Sook-Hyang Jeong

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O-044 Intention-to-Treat Analysis of Various Treatment Outcomes for Hepatocellular Carcinoma Defined BCLC Stage A with Portal Hypertension ·· 42Sung Won Jung, Dong-Sik Kim, Young Dong Yu, Jae Hyun Han, Sung Ock Suh

6. Liver Cancer, Clinical (II)

O-045 Retreatment with TACE: Transition of Model to Estimate Survival in Ambulatory Hepatocellular Carcinoma Patients Helps Decision ·············· 43Young Youn Cho, Su Jong Yu, Jung-Ju Yoo, Minjong Lee, Dong Hyeon Lee, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Jung-Hwan Yoon

O-046 The Validation of a New Modified Child-Turcotte-Pugh Score Using Insulin-Growth Factor-1 as a Prognostic Model for Hepatocellular Carcinoma·························································································································································································································· 43

Hyeki Cho, Dong Hyeon Lee, Jeong-Hoon Lee, Yuri Cho, Jung-Ju Yoo, Minjong Lee, Young Youn Cho, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

O-047 Optimal Staging of Single Large Hepatocellular Carcinoma ······························································································································ 44Tae Hyung Kim, Young Kul Jung, Chang Ho Jung, Yeon Seok Seo, Ji Hoon Kim, Yang Jae Yoo, Seong Hee Kang, Sun Young Yim, Sang Jun Suh, Hyunggin An, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun, Soon Ho Um

O-048 Survival of Hepatocellular Carcinoma Patients According to Recommended Treatment by the Barcelona Clinic Liver Cancer or Hong Kong Liver Cancer Staging System in Hepatitis B Endemic Area ····················································································································································· 44Dong Hyun Sinn, Dae Geon Ahn, Jung Hee Kim, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo

O-049 Comparison of Staging Systems for the Prediction of Prognosis in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization ·························································································································································································· 44Sung Won Lee, Nam Ik Han, Hyun Yang, Hae Lim Lee, Hee Chul Nam, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

O-050 Analysis of Clinical Outcomes According to Disease Progression Pattern in BCLC-B Hepatocellular Carcinoma Patients who Received Repeated Transarterial Chemoembolization ······································································································································································ 45Jung Hee Kim, Woo Kyoung Jeong, Won Sohn, Dong Hyun Sinn, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo, Yong-Han Paik

O-051 Korean Validation and Comparison of Prognostic Scores for Transarterial Chemoembolization: ART, ABCR, HAP, and Modified HAP ············ 45Hyun Yang, Soonkyu Lee, Hae Lim Lee, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

O-052 Reappraisal of Portal Vein Tumor Thrombosis as a Prognostic Factor for Patients with Hepatocellular Carcinoma ··········································· 45Young Chang, Su Jong Yu, Minjong Lee, Joon Yeul Nam, Hongkeun Ahn, Hyeki Cho, Yuri Cho, Jung-Ju Yoo, Dong Hyeon Lee, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Jung-Hwan Yoon

O-053 Intraoperative Real-time Elastography for Differential Diagnosis of Liver Tumors ······························································································ 46Kiyohiko Omichi, Yosuke Inoue, Hiroko Okinaga, Taku Aoki, Yasuhiko Sugawara, Junichi Arita, Junichi Kaneko, Nobuhisa Akamatsu, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo

7. Surgery (I)

O-054 Clinical Implications of Segmental Gallbladder Adenomyomatosis : Single Center Experience ·········································································· 46Jae Young Kim, Jae Keun Kim, Joon Seong Park, Dong Sup Yoon

O-055 Is it Fair to Routinely Insert the Drain after Laparoscopic Cholecystectomy for Acute Cholecystitis?: A Randomized Multicenter Prospective Controlled Trial ··················································································································································································································· 47Eun Young Kim, Tae Ho Hong

O-056 Yonsei Criteria in Minimally Invasive Surgery for Left Sided Pancreatic Cancer ································································································· 47Sung Hwan Lee, Chang Moo Kang, Ho Kyoung Hwang, Woo Jung Lee

O-057 Activation of Autophagy by Everolimus Confers Hepatoprotection against Hepatic Ischemia-Reperfusion Injury ············································· 47Say-June Kim, Na Yong Lee, Jae Woo Park, Sang Kuon Lee

O-058 Long Term Outcome after Resection of Intermediate (BCLC B) Hepatocellular Carcinoma: Comparison to Transarterial Chemoembolization·························································································································································································································· 48

Jun Young Kim, Dong Hyun Sinn, Gyu-Seong Choi, Jong Man Kim, Choon Hyuck David Kwon, Jae-Won Joh, Sung Wook Shin, Sung Ki Cho, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Byung Chul Yoo, Seung Woon Paik

O-059 Survival Outcome of Hepatic Epithelioid Hemangionendothelioma - A Systematic Review and an Institutional Study ······································ 48Hyo-Sin Kim, Joon Hyop Lee, Nam-Joon Yi, Hyeyoung Kim, Sung-Sik Han, Seong Hoon Kim, Sang-Jae Park, Kwang-Woong Lee, Kyung-Suk Suh

O-060 Long-Term Outcome of Hepatic Resection for Combined Hepatocellular Carcinoma and Cholangiocarcinoma ··············································· 49Young-In Yoon, Shin Hwang, Jong-Woo Lee, Young-Joo Lee, Chul-Soo Ahn, Ki-Hun Kim, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Sung-Gyu Lee

O-061 False-Positive Diagnosis of Hepatocellular Carcinoma after Liver Resection ······································································································· 49Hong Eun Lee, Hyeyoung Kim, Kwang-Woong Lee, Nam-Joon Yi, Hae Won Lee, Young Rok Choi, Suk Kyun Hong, Kyungchul Yoon, Hyo-Sin Kim, Kyung-Suk Suh

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O-062 Defining Surgical Difficulty According to the Perceived Complexity of Liver Resection: Validation of a Complexity Classification in Prospective Liver Resection Cohort in Patients with Hepatocellular Carcinoma ································································································· 50Paramin Muangkaew, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon, Young Rok Choi, Jae Yool Jang, Hanlim Choi, Jae Seong Jang, Seong Uk Kwon

8. HBV (I)

O-063 Relationship Between Regulatory T Cells and Hepatitis B Virus-Specific Effector T Cell Responses and Its Clinical Correlation in Patients with Chronic Hepatitis B ········································································································································································································· 50Wonseok Kang, Jun Yong Park, Min Kyung Jung, Young Jun Choi, Jiwon Lee, Seung Up Kim, Do Young Kim, Kwang-Hyub Han, Eui-Cheol Shin, Sang Hoon Ahn

O-064 Distribution of Quantitative HBsAg Level According to Serum HBV DNA Level in Chronic Hepatitis B; Treatment Naïve versus On-treatment·························································································································································································································· 50

Hye Won Lee, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Hye Jin Ku, Kwang-Hyub Han, Sang Hoon Ahn

O-065 Clinical Significance of Serum Quantitative Hepatitis B Surface Antigen Levels in Hepatitis B e-Antigen Negative Chronic Hepatitis B Patients with Elevated Hepatitis B Virus DNA Levels ······················································································································································· 51Jem Ma Ahn, Dong Hyun Sinn, Ja Ryong Jeon, Jung Hee Kim, Ju Yeon Cho, Won Sohn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo

O-066 A Study to Evaluate Dynamics Changes of HBsAg Quantity and its Relation with HBeAg Seroconversion Following 48 Weeks Pegylated-interferon-alpha Treatment in Patients with HBeAg Positive Chronic Hepatitis B after Long Term Nucleos(t)ide Analogue Maintenance Therapy: Interim Analyses ················································································································································································· 51Jeong Heo, Hyun Young Woo, Won Young Tak, Soo Young Park, Won Lim, Young Mi Hong, Young Oh Kweon, Ki Tae Yoon, Mong Cho

O-067 Pegylated-interferon Alpha Therapy for Treatment-experienced Chronic Hepatitis B Patients ··········································································· 52Ming-Lun Yeh, Cheng-Yuan Peng, Chia-Yen Dai, Hsueh-Chou Lai, Chung-Feng Huang, Jee-Fu Huang, Ming-Lung Yu, Wan-Long Chuang

O-068 Long-term Entecavir Treatment in a Large Cohort of Chronic Hepatitis B: A Prospective Real Life Data up to 8-year Follow-up ······················ 52Kyu Sik Jung, Hye Won Lee, Jun Yong Park, Hye Jin Ku, Beom Kyung Kim, Seung Up Kim, Do Young Kim, Kwang-Hyub Han, Sang Hoon Ahn

O-069 Long Term Clinical Outcome in Chronic Hepatitis B Patients with Partial Virologic Response to Entecavir Treatment ······································· 52Kyu Sik Jung, Hye Won Lee, Jun Yong Park, Hye Jin Ku, Beom Kyung Kim, Seung Up Kim, Do Young Kim, Kwang-Hyub Han, Sang Hoon Ahn

O-070 Quality of Life among Korean Patients with Chronic Hepatitis B ······················································································································· 53Yeonsoo Jang, Ji Yeon Lee, Sang Eun Lee, Eun Kyung Kwon, Sang Hoon Ahn

O-071 Assessing Dietary Status in Korean Patients with Chronic Hepatitis B ··············································································································· 53Yeonsoo Jang, Hyung Mi Kim, Ji Yeon Lee, Sang Eun Lee, Eun Kyung Kwon, Bo Mi Ham, Sang Hoon Ahn

9. HBV (II)

O-072 Randomized Comparison of Tenoforvir versus Entecavir plus Adefovir in Suboptimal Responder for Lamivudine-adefovir Therapy in Patients with rt204I/V Mutation ····························································································································································································· 54Sae Hwan Lee, Hong Soo Kim, Sang Gyune Kim, Young Seok Kim, Dae Won Jun, Young Don Kim, Gab Jin Cheon, Tae Yeob Kim, Joo Hyun Sohn, Byung Seok Lee, Soung Won Jeong, Jae Young Jang, Boo Sung Kim

O-073 Tenofovir Monotherapy vs Tenofovir and Entecavir Combination Therapy in Adefovir-Resistant Chronic Hepatitis B Patients with Multiple Drug Failure: 96-Weeks Results of a Randomized Trial ··························································································································································· 54Byung Chul Yoo, Young-Suk Lim, Kwan Soo Byun, So Young Kwon, Yoon Jun Kim, Jihyun An, Han Chu Lee, Yung Sang Lee

O-074 Comparing Antiviral Efficacy of Tenofovir Monotherapy and Tenofovir Based Combination Therapy in Antiviral Resistant Chronic Hepatitis B: An Interim Result of Multicenter Cohort Study ······················································································································································· 55Kyu Sik Jung, Beom Kyung Kim, Ki Tae Yoon, Hana Park, Chang Wook Kim, Jin-Woo Lee, Young Seok Kim, Jung Il Lee, Jun Yong Park, Seung Up Kim, Do Young Kim, Sang Gyune Kim, Young-Joo Jun, Hee Yeon Kim, Seong Gyu Hwang, Mong Cho, Kwan Sik Lee, Kwang-Hyub Han, Sang Hoon Ahn

O-075 The Analysis of Efficacy and its Influencing Factors of Tenofovir Based-rescue Therapy in Chronic Hepatitis B Patients According to Genotypic Resistant Mutation to Various Drugs ················································································································································································ 55Seong Hee Kang, Ji Hoon Kim, Young Sun Lee, Tae Suk Kim, Yang Jae Yoo, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

O-076 Comparison of the Efficacy of Entecavir and Tenofovir in Nucleos(t)ide Analogue-experienced Chronic Hepatitis B Patients ··························· 55Eun Ju Cho, Jeong-Hoon Lee, Yuri Cho, Yun Bin Lee, Jeong-Ju Yoo, Minjong Lee, Dong Hyeon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon, Hyo-Suk Lee

O-077 Comparison of Early Virologic Response between Entecavir and Tenofovir in Chronic Hepatitis B: A Propensity Score Matching Analysis ······· 56Jung Wha Chung, Won Keun Si, Joo Yeong Baeg, Junhyeon Cho, Eun Sun Jang, Sook-Hyang Jeong, Jin-Wook Kim

O-078 Long Term Follow Up of Chronic Hepatitis B Patients after Oral Antiviral Treatment Discontinuation ······························································· 56Seong Hee Kang, Jong Eun Yeon, Young Sun Lee, Tae Suk Kim, Yang Jae Yoo, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Ji Hoon Kim, Hyung Joon Yim, Kwan Soo Byun

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O-079 Discontinuation of Antiviral Prophylaxis in Hepatitis B Virus Infected Patients Who Received Cytotoxic Chemotherapy: Outcomes and Predictors·························································································································································································································· 56

Kyung Sook Lim, Hyo Jin Kim, Jung Hee Kim, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo

10. Cirrhosis / Liver Fibrosis (I)

O-080 Small Intestinal Bacterial Overgrowth and Esophageal Varix Correlated with Alterations of Gut Microbiome in Liver Cirrhosis ························ 57Jae Yoon Jeong, Dae Won Jun, Ho Soon Choi, Byung Chul Yoon, Joo hyun Sohn, Chang Hong Lee, Oh Young Lee, Kang Nyeong Lee, Hang Lak Lee

O-081 Clinical Impact of Subclinical Ascites in HBV-related Cirrhotic Patients Treated with Antiviral Treatment ·························································· 57Sun Young Yim, Hongkeun Ahn, Jeong-Hoon Lee, Seung Up Kim, Sang Gyune Kim, Young Seok Kim, Jeong Han Kim, Won Hyeok Choe, Tae Yeob Kim, Young Kul Jung, Sang Jun Suh, Ki Tae Suk, Hyunggin An, Yeon Seok Seo, Soon Ho Um

O-082 Risk Assessment of Hepatocellular Carcinoma Development in Patients with Chronic Hepatitis B Starting Antiviral Therapy: Transient Elastography versus Liver Biopsy ····························································································································································································· 58Mi Na Kim, Yeon Seok Seo, Seung Up Kim, Sang Gyune Kim, Soon Ho Um, Kwang-Hyub Han, Young Seok Kim

O-083 Adjusting the Fibrotic Burden Using Transient Elastography Reveals Similar Long-term Outcomes in Chronic Hepatitis B Patients Treated with Lamivudine or Entecavir: A Propensity- score Matched Analysis ························································································································ 58Hye Soo Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han

O-084 Establishing a New Tool for Quantitative Histologic Assessment of Hepatic Cirrhosis ······················································································· 59Yan Wang, Qian-Jin Feng, Jin-Lin Hou

O-085 Serine Protease Omi/HtrA2 Reduces Oxidative Stress and Preserves Mitochondrial Function in Liver Fibrosis ···················································· 59Joon Ho Lee, Sung Woo Hong, Wonhee Hur, Jung-Hee Kim, Jung Eun Choi, Sung Min Kim, Eun Byul Lee, Seung Kew Yoon

O-086 Liver Stiffness Measured by Magnetic Resonance Elastography is not Associated with Recurrence after Curative Treatment of Hepatocellular Carcinoma ········································································································································································································· 60Young Youn Cho, Dong Hyeon Lee, Jeong-Hoon Lee, Dong Ho Lee, Ju Hyeon Jeon, Jeong Min Lee, Joon Koo Han, Hongkeun Ahn, Hyeki Cho, Jung-Ju Yoo, Minjong Lee, Yuri Cho, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung Min Lee, Jung-Hwan Yoon

11. Liver Cancer, Clinical (III)

O-087 Surgical Treatment for Early Stage HCC in Transplantation Era ························································································································· 60Hee Jung Wang, Bong Wan Kim, Young Keun Park

O-088 Usefulness of Real-time Contrast Enhanced Ultrasound (CEUS)-Guided Radiofrequency Ablation in Hepatocellular Carcinoma ······················ 60Eui Joo Kim, Yun Soo Kim, Joo Il Kim, Seung Kak Shin, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim

O-089 Validity of Barcelona Clinic Liver Cancer Stage A: Association of Tumor Size and Overall Survival in a Single Hepatocellular Carcinoma ········· 61Yeonjung Ha, Mi Jung Jun, Ju Hyun Shim, Kang Mo Kim, Young-Suk Lim, Han Chu Lee

O-090 Combining Transarterial Chemoembolization with Radiofrequency Ablation versus Hepatic Resection by Using Propensity Score Matching in Hepatocellular Carcinoma ················································································································································································· 61Young Kul Jung, Joo Hee Park, Sang Jun Suh, Hyung Joon Yim, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim, Ji Hoon Kim, Jong Eun Yeon, Kwan soo Byun, Yeon Seok Seo, Soon Ho Um, Ho Sang Ryu

O-091 Multi-analyte Analysis of Serum Cytokines to Predict Treatment Outcome in Patients with Hepatocellular Carcinoma Treated with Radiotherapy·························································································································································································································· 62

Hyejung Cha, Eun Jung Lee, Jinsil Seong

O-092 Comparing Treatment Outcomes between Radioembolization Using Yttrium-90 Microspheres and Concurrent Chemoradiation Therapy for Locally Advanced for Hepatocellular Carcinoma ··························································································································································· 62Mi Yeon Kim, Kyu Sik Jung, Do Young Kim, Jinsil Seong, Jong Yun Won, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Sang Hoon Ahn, Kwang-Hyub Han

O-093 Development of a Model Predicting Survival for Recurrent or Progressive Hepatocellular Carcinoma ······························································· 62Sang Il Choi, Ami Yu, Bo Hyun Kim, Eun Jung Ko, Sun Seob Park, Byung Ho Nam, Joong-Won Park

O-094 Estimation of Survival after Stopping Sorafenib in Patients with Advanced Hepatocellular Carcinoma: Development and Validation of the “NEXT score” ···································································································································································································· 63Hyun Soo Kim, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han

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12. Surgery (II)

O-095 The Hypoxic Conditioned Secretome from Human Adipose- derived Stem Cells Improves Mouse Liver Regenerative Potential through the Suppression of SOCS3 ·········································································································································································································· 63Say-June Kim, Na Young Lee, Jae Woo Park, Sang Kuon Lee

O-096 Outcome of Living Donor Liver Transplantation Using Partial Liver Allografts with Dual Arterial Supply ··························································· 64Kyo Won Lee, Choon Hyuck David Kwon, Chan Woo Cho, Nuri Lee, Dong Kyu Oh, Byung Gon Na, Jin Yong Choi, Wontae Cho, Seunghwan Lee, Jong Man Kim, Kyu Sung Choi, Jae Berm Park, Sung Joo Kim, Jae-Won Joh, Suk-Koo Lee

O-097 Outcomes and Recurrence Patterns after Non Anatomic Liver Resection for Solitary HCC ················································································ 64Hun Tak Ha, Jae Min Chun, Yoon Jin Hwang, Young Seok Han

O-098 Analysis of Risk Factors for Post-hepatectomy Thrombosis ································································································································ 65Jae Hyun Han, Dong-Sik Kim, Young Dong Yu, Sung Won Jung, Sung Ock Suh

O-099 Which is the Predictable Value of Post-transplant HCC Recurrence between Tumor-related Factors at the Initial Diagnosis and the Transplantation?·························································································································································································································· 65

Jae Geun Lee, Juhan Lee, Jung Jun Lee, Myoung Soo Kim, Man Ki Ju, Gi Hong Choi, Jin Sub Choi, Soon Il Kim, Dong Jin Joo

O-100 Laparoscopic Caudate Lobectomy ····································································································································································· 66Dong Kyu Oh, Choon Hyuck David Kwon, Byung Gon Na, Kyo Won Lee, Won Tae Cho, Seung Hwan Lee, Jin Yong Choi, Gyu Seong Choi, Jae Bum Park, Jong Man Kim, Jae Won Joh, Sung Joo Kim, Suk Koo Lee

O-101 Conjoined Unification Venoplasty for Graft Double Portal Vein Branches as a Modification of Autologous Y-graft Interposition ····················· 66Shin Hwang, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Deok-Bog Moon, Chul-Soo Ahn, Ki-Hun Kim, Gil-Chun Park, Young-In Yoon, Min-Ho Shin, Wan-Jun Kim, Sung-Gyu Lee

O-102 Clinical Analysis of Recurrent Hepatocellular Carcinoma after Living Donor Liver Transplantation ···································································· 67Gun Hyung Na, Eun Young Kim, Tae Ho Hong, Young Kyoung You, Dong Goo Kim

O-103 Alterations of Hepatocellular Bile Salt Transporters and Effects of Immunosuppressants after Warm Ischemic Injury in Rats ··························· 67Hyeyoung Kim, Kwang-Woong Lee, Seung Cheol Oh, Geun Hong, Nam-Joon Yi, Hae Won Lee, Young Rok Choi, Suk-Won Suh, Jaehong Jeong, Suk Kyun Hong, Kyungchul Yoon, Hyo-Sin Kim, Kyung-Suk Suh

13. Cirrhosis / Liver Fibrosis (II)

O-104 Systematic Analysis Reveals Cromolyn Sodium as Anti-fibrotic Agent to Target Both Hepatocytes and Hepatic Stellate Cells ·························· 68Eun Young Cho, Jin Woo Choi, Haak Cheoul Kim

O-105 The Association between the Hepatic Venous Pressure Gradient and Portosystemic Collateral Vessels in Portal Hypertension and its Complications·························································································································································································································· 68

Won Young Park, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim, Yong Jae Kim, Suyeon Park, Young Ok Kim

O-106 The Association between the Grade and Frequency of Thoracic Duct Dilatation with Portal Hypertension and Variables in Advanced Liver Cirrhosis·························································································································································································································· 69

Seung Woon Park, Soo Youn Ham, Sun Young Yim, Tae Hyung Kim, Jemma Ahn, Han Ah Lee, Soon Ho Um, Yeon Seok Seo, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Chang Duck Kim, Ho Sang Ryu, Eun Sun Kim, Bora Keum

O-107 Urine Cystatin C is a Strong Predictor for Short-term Mortality and Therapeutic Response to Terlipressin in Cirrhotic Patients with Serum Creatinine Greater than 1.5mg/dl ······················································································································································································ 69Sang Gyune Kim, Young Seok Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Young Don Kim, Gab Jin Cheon, Boo Sung Kim

O-108 A New Prognostic Model for 1-year Mortality in Patients with Decompensated Heaptits B Virus-related Liver Cirrhosis Receiving Antiviral Treatment·························································································································································································································· 70

Tae Hyung Kim, Dae Hoe Gu, Soon Ho Um, Seok Bae Yoon, Tae Jung Yun, Sun Young Yim, Jin Young Jung, Yeon Seok Seo, Hyung Joon Yim, Bora Keum, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Chang Duck Kim, Ho Sang Ryu

O-109 Change of the Causative Factors of Liver Cirrhotic Patients in Daegu-Gyeongbuk Province during Recent 15 Years ········································ 70 Jeong Min Kim, Wang Yong Choi, Woo Jin Chung, Byoung Kuk Jang, Jae Seok Hwang, Heon Ju Lee, Moon Joo Hwang, Won Young Tak, Young Oh Kweon, Soo Young Park, Su-hyun Lee, Chang Hyeong Lee, Byung Seok Kim, Si Hye Kim, Jeong Ill Suh, Jun Gi Park, Daegu-Gyeongbuk Liver Study Group (DGLSG)

O-110 Outcomes of Patients Who Treated with Sengstaken-Blakemore Tube for Uncontrolled Variceal Hemorrhage ················································ 71Ja Yun Choi, Yun Won Jo, Sang Soo Lee, Hye Won Oh, Cha Young Kim, Ra Ri Cha, Jin Joo Kim, Jae Min Lee, Hong Jun Kim, Hyun Jin Kim, Tae Hyo Kim, Woon Tae Jung, Ok Jae Lee

O-111 Liver Cirrhosis and Cancer: Comparison of Mortality ········································································································································ 71Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim

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O-112 Liver Disease and Cancer: Comparison of Economic Burden ····························································································································· 71Wankyo Chung, Changik Jo, Woo Jin Chung, Dong Joon Kim

14. HBV (III)

O-113 Hepatitis B Virus Reactivation in HBsAg-negative and Anti-HBc-positive Patients Undergoing Rituximab-based Chemotherapy for Lymphoma·························································································································································································································· 72

Yuri Cho, Su Jong Yu, Dong Hyeon Lee, Minjong Lee, Jeong-ju Yoo, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Tae Min Kim, Dae Seog Heo, Yoon Jun Kim, Jung-Hwan Yoon

O-114 Prepartum Use of Telbivudine on Preventing Mother-to-Child Transmission of Hepatitis B Virus: A Prospective Non-Randomized Open-Labeled Multi-Center Study ···························································································································································································· 72Chung-Hwa Park, In-Yang Park, Juyoung Lee, Sang Bong Ahn, Jung Hwan Shin, Young Min Ahn, Hyun Seung Lee, Sa-Jin Kim, U Im Chang, Chang Wook Kim, Se Hyun Jo, Young Lee, Jong-Hyun Kim, Si Hyun Bae, Mother-to-Child Transmission of Hepatitis B Prevention Working Group

O-115 A Randomized Trial Evaluating the Antiviral Efficacy of Switching from Lamivudine Plus Adefovir to Tenofovir Monotherapy in Lamivudine-resistant Chronic Hepatitis B Patients with Undetectable Hepatitis B Virus DNA - The 48 week Interim Analysis ···························································· 73Heon Ju Lee, Jeong Min Kim, Young Oh Kweon, Soo Young Park, Jeong Heo, Hyun Young Woo, Jae Seok Hwang, Woo Jin Chung, Chang Hyeong Lee, Byung Seok Kim, Jeong Ill Suh, Won Young Tak, Byoung Kuk Jang

O-116 Association between HBeAg Seroconversion and Risk of Hepatocellular Association between HBeAg Seroconversion and Risk of Hepatocellular Carcinoma during Treatment with Lamivudine or Entecavir for Chronic Hepatitis B ························································································· 73Jihyun An, Young-Suk Lim, Hwa Jung Kim, Hyung-Don Kim, Gi-Ae Kim

O-117 Entecavir and Tenofovir More Effectively Reduce the Recurrence of Hepatitis B Virus-related Hepatocellular Carcinoma after Curative Treatment than Low-potent Antivirals ················································································································································································ 73Hongkeun Ahn, Jeong-Hoon Lee, Hyeki Cho, Young Youn Cho, Minjong Lee, Jeong-Ju Yoo, Yuri Cho, Dong Hyeon Lee, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon, Hyo-Suk Lee

O-118 Risk of Hepatocellular Carcinoma and Mortality among Treated Patients with Chronic Hepatitis B vs Chronic Hepatitis C ······························ 74Gi-Ae Kim, Young-Suk Lim

O-119 Prevalence and Significance of Occult Hepatitis B Virus Infection in Chronic Hepatitis C in South Korea ·························································· 74Junhyeon Cho, Sang Soo Lee, Joo Yeong Baeg, Yun Suk Choi, Yejoo Jeon, Jung Wha Chung, Eun Sun Jang, Jin Wook Kim, Sook-Hyang Jeong

O-120 Long-term Outcome in Chronic Hepatitis B Patients with HBsAg Seroclearance ······························································································· 75Jung Wha Chung, Won Keun Si, Joo Yeong Baeg, Junhyeon Cho, Eun Sun Jang, Sook-Hyang Jeong, Jin-Wook Kim

O-121 Clinical Outcome of Long-term Entecavir Therapy in Patients with Compensated and Decompensated Cirrhosis: Benefit for Reversal of Cirrhosis·························································································································································································································· 75

Hye Won Lee, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Hye Jin Ku, Kwang-Hyub Han, Sang Hoon Ahn

15. Alcoholic / Metabolic / Genetic / Immunologic Liver Disease

O-122 Intrahepatic Fat Distribution and Variability According to Multiple-Echo Dixon Technique in Patients with Liver Disease ································· 75Bo Kyeong Kang, Dae Won Jun, Chang Hong Lee, Kiseok Jang

O-123 Reverse Correlation with FXR Expression of Peripheral Mononuclear Cell and NPC1L1 Expression of Terminal Ileum in Non-alcoholic Fatty Liver Disease·························································································································································································································· 76

Sang Bong Ahn, Dae Won Jun, Kiseok Jang, Byoung Kwan Son, Jae Yoon Jeong, Joo Hyun Sohn, Chang Hong Lee

O-124 Aronia Melanocarpa Extract Ameliorates Hepatic Lipid Metabolism through PPAR 2 Downregulation ····························································· 76Chung-Hwa Park, Jung-Hee Kim, Eun Byul Lee, Wonhee Hur, Hyoung-Jin Park, Seung Kew Yoon

O-125 Prevalence and Predictors of Significant Liver Fibrosis among Subjects with Transient Elastography-defined Nonalcoholic Fatty Liver Disease·························································································································································································································· 76

Hye Won Lee, Seung Up Kim, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han

O-126 A Prospective Comparative Study to Assess the Accuracy of Fibroscan in Evaluating Liver Steatosis ································································· 77Won Young Park, Eui Ju Park, Jae Young Jang, Soung Won Jeong, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim, So young Jin, Suyeon Park, Young Ok Kim

O-127 Assessment of Risk Factors in Patient with Non-obese and Obese Non-alcoholic Fatty Liver Disease ································································ 77Joo Hee Kwak, Dae Won Jun, Yong Kyun Cho, Oh Young Lee, Ho Soon Choi, Byung Chul Yoon, Chang Hong Lee, Joo Hyun Sohn, Jae Yoon Jeong, Kang Nyeong Lee, Hang Lak Lee

O-128 Demographic, Lifestyle, Medical and Familial Factors Associated with Primary Biliary Cirrhosis in Korea ··························································· 77Kyung-Ah Kim, Young Seok Kim, Woo Jin Chung, Sang Hoon Park, Dae Hee Choi, Sook-Hyang Jeong

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O-129 Nationwide, Population-based Prevalence, Complications, Comorbidity and Medical cost of Primary Biliary Cirrhosis in South Korea, 2009-2013·························································································································································································································· 78

Kyung-Ah Kim, Moran Ki, Hwa Youg Choi, Bo Hyun Kim, Eun Sun Jang, Sook-Hyang Jeong

O-130 Oral Intake of Anti-hangover Substance Increases Aldehyde Dehydrogenase Activity: New Preventive and Therapeutic Potentials? ················ 78Bossng Kang, Chae-Young Bang, Se-Young Choung, Kyungwoo Choi

Poster Oral Presentation

HBV (I)

PO-001 Assessment of Insufficient Viral Response During Entecavir Therapy in Treatment Naïve Chronic Hepatitis B ··················································· 83Tae Suk Kim, Ji Hoon Kim, Young-Sun Lee, Yang Jae Yoo, Seong Hee Kang, Sang-June Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

PO-002 Prolonged Entecavir Therapy Improves Liver Fibrosis Estimated by APRI in Majority of Naïve Patients with a Partial Virological Response ········ 83Hee Yeon Kim, Chang Wook Kim, Hyung Gyu Choi, Ji Young Kim, Chang Don Lee, Seung Kew Yoon, Jong Young Choi, Si Hyun Bae, Yoo Dong Won, Soo Lim Lee

PO-003 Efficacy of Continuous Tenofovir Monotherapy for Partial Virologic Response to Tenofovir in Treatment-Naïve Chronic Hepatitis B Patients ·· 83Min Keun Kim, Sun Mi Kang, Si Hye Kim, Jeung Eun Song, Ga Young Kim, Sang Ah Baek, Chang Hyeong Lee, Byung Seok Kim

PO-004 Tenofovir and Entecavir has Similar Renal Adverse Events on Hepatocelluar Carcinoma Patients Treated with Transarterial Chemoembolization·························································································································································································································· 84

Young Youn Cho, Su Jong Yu, Jung-Ju Yoo, Minjong Lee, Dong Hyeon Lee, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Jung-Hwan Yoon

PO-005 Renal Tubular Dysfunction of Prophylactic Treatment with Anti-hepatitis B Immunoglobulin Combined Lamivudine and Adefovir Dipivoxil in Liver Recipients ·········································································································································································································· 84Jae Geun Lee, Juhan Lee, Jung Jun Lee, Seung Hwan Song, Man Ki Ju, Gi Hong Choi, Myoung Soo Kim, Jin Sub Choi, Soon Il Kim, Dong Jin Joo

HBV (II)

PO-006 Lamivudine vs. Entecavir for the Newly Diagnosed Hepatitis B-Virus Related Hepatocellular Carcinoma ··························································· 84Jung Hee Kim, Dong Hyun Sinn, Kyunga Kim, Hyeseung Kim, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo

PO-007 Usefulness of Transient Elastography in Evaluation of Antiviral Effect with Oral Nucleos(t)ides in Patients with Chronic Hepatitis B Virus (HBV) Infection·························································································································································································································· 85

Angelo Lozada, Hae Lim Lee, Hyun Yang, Soonkyu Lee, Si Hyun Bae, Seung Kew Yoon

PO-008 Can Neutrophil to Lymphocyte Ratio Discriminate the Immune Phases of Chronic Hepatitis B Patients? ·························································· 85Young Woon Kim, Jung Hyun Kwon, Jeong Won Jang, Sung Won Lee, Soon Woo Nam, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

PO-009 Association between Insulin Resistance and HBV DNA Titer in Patients with Chronic Hepatitis B ····································································· 86Won Keun Si, Jung Wha Chung, Jun Hyeon Cho, Joo Yeong Baeg, Sook-Hyang Jeong, Eun Sun Jang, Jin-Wook Kim

PO-010 Experiences in Capacity Building for Family Physicians in the Diagnosis and Management of Chronic Hepatitis B Infection ····························· 86Limuel Anthony B. Abrogena

PO-011 Prevalence and Risk Factors of Hepatitis B Infection in Pregnant Women at the Prenatal Clinic of the Philippine General Hospital ·················· 87Gian Carlo Carpio, Aubrey Taguba, Lana Tan

Cell Biology / Molecular Biology

PO-012 Establishment of Cell-to-Cell in Silico Network Model based on Transcriptome Profiles of Various Types of Cells during the Process of Liver Fibrosis·························································································································································································································· 87

Jung Eun Choi, Wonhee Hur, Jung-Hee Kim, Sung Woo Kim, Sung Woo Hong, Eun Byul Lee, Sung Min Kim, Joon Ho Lee, Daehee Hwang, Seung Kew Yoon

PO-013 Hereditary Persistence of Alpha-fetoprotein and Mutational Analysis of Alpha-fetoprotein Promoter, Enhancer, and Silencer Regions ··········· 88Yejoo Jeon, Yoon Suk Choi, Eun Sun Jang, Jin Wook Kim, Sook-Hyang Jeong

PO-014 Demethylation of BASP1 by Berberine Attenuates Progression of Human Hepatocellular Carcinoma Cells ······················································ 88Jeong-Ju Yoo, Jung-Hwan Yoon, Dong Hyeon Lee, Yuri Cho, Yun Bin Lee, Minjong Lee, Young Youn Cho, Won-mook Choi, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Chung Yong Kim, Hyo-Suk Lee

PO-015 Inactivating Mechanism of ATBF1 Gene In Hepatocellular Carcinomas ············································································································· 88Chang Jae Kim, Jung Woo Shin, Seok Won Jung, Bo Ryung Park, Neung Hwa Park

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PO-016 Ideal Sphere Forming Culture Condition to Maintain the Stemness in Hepatocellular Carcinoma Cell Line ······················································ 88Seon Ok Min, Sang Woo Lee, Seon Young Park, Kyung Sik Kim

PO-017 Inhibition of Hepatic Stellate Cells by Bone Marrow-derived Mesenchymal Stem Cells in Hepatic Fibrosis ························································ 89Yoon Ok Jang, Baek Gyu Jun, Soon Ku Baik

Cirrhosis / Liver Fibrosis (I)

PO-018 Noradrenaline vs Terlipressin for Hepatorenal Syndrome (No to Hepatorenal Syndrome): A Meta Analysis ······················································ 90Samala, Kenneth G., Pedracio, Farrah Haidee Lynne P., Taquiso, Jezreel L., Ong, Janus P.

PO-019 Validation of Relationship between Variation in the Promoter Region of Glutaminase Gene and Development of Hepatic Encephalopathy in East Asian ················································································································································································································· 90Jem Ma Ahn, Soon Ho Um, Han Ah Lee, Seung Woon Park, Chang Ho Jung, Tae Hyung Kim, Sun Young Yim, Chang Ha Kim, Hyuk Soon Choi, Eun Sun Kim, Bora Keum, Young Kul Jung, Ji Hoon Kim, Yeon Seok Seo, Hyung Joon Yim, Yoon Tae Jeen, Jong Eun Yeon, Hong Sik Lee, Hoon Jai Chun, Kwan Soo Byun, Chang Duck Kim, Ho Sang Ryu

PO-020 A Family with Four Siblings Affected with Primary Biliary Cirrhosis ··················································································································· 91S.H. Park, I.H. Moh, S.E. Kim, J.W. Park, K.T. Seok, H.S. Kim, M.K. Jang, D.J. Kim, C.K. Park, M.E. Hong, M.S. Lee

PO-021 A Retrospective Study on Noninvasive Predictors of Esophageal Varices In Patients with Liver Cirrhosis, a Makati Medical Center Experience · 91Gabriel Romualdo L. Valero, Ernesto Olympia

PO-022 Blood Urea Nitrogen to Creatinine Ratio Reflects Current Variceal Bleeding in Patient with Liver Cirrhosis ······················································ 92Sang Jun Suh, Young Kul Jung, Sun Young Yim, Young Sun Lee, Tae Suk Kim, Yang Jae Yoo, Sung Hee Kang, Tae Hyung Kim, Jong Jin Hyun, Ji Hoon Kim, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Soon Ho Um, Kwan Soo Byun

PO-023 Low Baseline Serum Creatinine and Small Increase in Creatinine Predict Mortality in Cirrhotic Patients with Ascites ······································· 92Sung Eun Kim, Ji won Park, Young Rim Song, Choong Kee Park

Alcoholic / Metabolic / Genetic / Immunologic Liver Disease

PO-024 Genetic Polymorphism Associated with the Development of Metabolic Syndrome and Non Alcoholic Fatty Liver Disease ································ 93Ji Su Kim, Joo Ho Lee, Yun Bin Lee, Hana Park, Seong Gyu Hwang, Sang Woon Choi

PO-025 Nonalcoholic Fatty Liver Disease (NAFLD) among Adult Patients with Type 1 Diabetes Mellitus: Prevalence and Association with Metabolic Syndrome and Cardiovascular Diseases ·············································································································································································· 93Mara Teresa T. Panlilio, Daveric Pagsisihan, Jeffrey M. Libuit, Aileen Azul-Bautista, Ramon Martin F. Banez, Allyn Rey B. Lomboy, Ivan Michael G. Vicente, Janus P. Ong, Cecilia Jimeno, Elizabeth Paz-Pacheco

PO-026 Efficacy of Supplementation with Vitamin B6, Vitamin B12, and Folate in Patients with Alcoholic Liver Disease ·············································· 93SY Ko, JH Kim, WH Choe, SY Kwon, HS Ahn, KP Kim, HB Chae

PO-027 Prevalence, Treatment Pattern and Healthcare-related Costs of Wilson’s Disease Using National Health Insurance Data from 2009-2013, South Korea·························································································································································································································· 94

Eun Sun Jang, Hwa Young Choi, Moran Ki, Bo Hyun Kim, Kyung-Ah Kim, Sook-Hyang Jeong

PO-028 Utility of Thromboelastography and Comparing with Traditional Coagulation Tests in Assessing the Risk of Bleeding and Thrombosis in Cirrhotics·························································································································································································································· 94

Vaibhav Somani, Apurva Shah, Deepak Amarapurkar

PO-029 Gilbert Syndrome in an Adolescent Male with Co-existing Glucose-6-phosphate Dehydrogenase Deficiency: A Case Report ·························· 95Princess A. Guevarra, Patricia Sun Te

Liver Caner, Clinical (I)

PO-030 Hepatocellular Carcinoma Risk in Chronic Hepatitis B Virus- infected Compensated Cirrhosis Patients with Low Viral Load ···························· 95Dong Hyun Sinn, Junggyu Lee, Daegeon Ahn, Juna Goo, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Byung Chul Yoo, Seung Woon Paik

PO-031 Influence of Hepatitis B Virus DNA Elevation on Recurrence of Hepatocellular Carcinoma after Surgical Resection and the Preventive Role of Antiviral Therapy ············································································································································································································· 95Yang Jae Yoo, Ji Hoon Kim, Young Sun Lee, Tae Suk Kim, Sung Hee Kang, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

PO-032 Anti-HBe Positivity is Protective for HCC Development in Naïve Hepatitis B Viral Cirrhotic Patients Treated with Long- term Entecavir Monotherapy·························································································································································································································· 96

Eun Sun Jang, Jong Ho Lee, Seong Min Chung, Jin-Wook Kim, Sook-Hyang Jeong

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PO-033 Serum Interleukin-6 Levels as a Predictive Marker of Recurrence in Patients with Hepatocellular Carcinoma Who Underwent Curative Treatment·························································································································································································································· 96

Hyo Jung Cho, Soon Sun Kim, Joo Han Park, Choong Kyun Noh, Jae Youn Cheong, Sung Won Cho

PO-034 Risk of Secondary Cancer after Diagnostic Radiation Exposure in Patients with Hepatocellular Carcinoma: A Big Data Analysis ······················ 97Moran Ki, Joong-Won Park, Hwa Young Choi, Chang Bok Lee, Ju Hee Lee, Young Hwan Koh

Surgery: Liver (I)

PO-035 Prognostic Impact of Tumor Growth Type on 7th AJCC Staging System for Intrahepatic Cholangiocarcinoma: A Single-center Experience of 659 Cases ················································································································································································································· 97Shin Hwang, Young-Joo Lee, Gi-Won Song, Kwang-Min Park, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Sung-Gyu Lee

PO-036 Safety and Feasiblity of Laparoscopic Major Hepatectomy (LMH) Post Portal Vein Embolization (PVE), A Case Series ······································· 97Nasser Alzerwi, Choon Hyuck David Kwon

PO-037 Isolated Caudate Lobectomy for Solitary Hepatocellular Carcinoma: Single-institution Experience with 33 Patients ········································· 98Min-Ho Shin, Shin Hwang, Yong-Jae Kwon, Young-Joo Lee, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Sung-Gyu Lee

PO-038 Effective Management of Male Primary Hepatic Choriocarcinoma: A Case Report and Literature Review ························································ 98Cheon-Soo Park, Young-Chel Ahn, Tae-Eun Kim, Sung-Gyu Lee

PO-039 Significance of Complete Anatomical Resection for Hepatocellular Carcinoma: A Case Report ········································································ 98Nadiar Musin, Kwang-Woong Lee, Adianto Nugroho, Hyeyoung Kim, Hyoshin Kim, Abylay Donbay, Nam-Joon Yi, Kyung-Suk Suh

PO-040 Damage Control Surgery for Liver Laceration with Major Vessel Injury: Vascular Control Followed by Delayed Hepatectomy ·························· 99Hee Joon Kim, Chol Kyoon Cho

Surgery: Liver (II)

PO-041 Locoregional Therapy in Patients with Hepatocellular Carcinoma: A Real Life Experience ················································································· 99Pratibha Sonawane, Deepak Amarapurkar

PO-042 Prediction of Post-hepatectomy Liver Insufficiency Using Liver Stiffness Measurement for the Patient with Hepatocellular Carcinoma ············ 99Jinhoon Nam, Dai Hoon Han, Jin Ho Lee, Jin Sub Choi

PO-043 Technical Advance to Prevent Hepatic Outflow Disturbance in Right Lobe Living Donor Liver Transplantation? : New Simplified One-orifice Venoplasty······················································································································································································································· 100

Joo Dong Kim, Dong Lak Choi

PO-044 Surgical Outcome of Laparoscopic Major Liver Resection - A Large Volume Center’s 10 Years’ Experience ··················································· 100Wontae Cho, Choon Hyuck David Kwon, Jin Yong Choi, Seung Hwan Lee, Jong Man Kim, Gyu Seong Choi, Jae-Won Joh, Sung Joo Kim, Gaab Soo Kim, Kwang Chul Koh, Jin Seok Heo

PO-045 Synergistic Anticancer Effect of Metformin in Combination with Immunosuppressant on Hepatocellular Carcinoma Cell Lines ···················· 100Suk-Won Suh, Kwang-Woong Lee, Yoo-Shin Choi, Hyeyoung Kim, Nam-Joon Yi, Kyung-Suk Suh

PO-046 Laparoscopic Right-sided Major Hepatectomy: Toward a Protocolization and Simplification ·········································································· 101Sung Hoon Choi

Surgery: Transplantation

PO-047 Outcomes of Living and Deceased Donor Liver Transplant Recipients according to The MELD score ······························································ 101Juhan Lee, Seung Hwan Song, Jae Geun Lee, Dong Jin Joo, Dae Hoon Han, Man Ki Ju, Jin Sub Choi, Soon Il Kim, Myoung Soo Kim

PO-048 Outcomes and Survival: A Single Center Analysis of Liver Transplantation Program ······················································································· 101Aiymkul Ashimkhanova, Kakharman Yesmembetov, Tokan Sultanalyiev, Gani Kuttymuratov, Adilbek Mukazhanov, Asan Zhexembayev, Mels Assykbayev, Yermakhan Assylkhanuly, Said Abdugaffarov

PO-049 Results of ABO Incompatible Liver Transplantation Using a Simplified Protocol at a Single Institution ···························································· 102Juhan Lee, Seung Hwan Song, Jae Geun Lee, Jung Jun Lee, Myoung Soo Kim, Man Ki Ju, Gi Hong Choi, Jin Sub Choi, Soon Il Kim, Dong Jin Joo

PO-050 Outcomes of Simultaneous Major Liver Resection and Colorectal Surgery for Colorectal Liver Metastases ····················································· 103Paramin Muangkaew, Jai Young Cho, Ho-Seong Han, Yoo-Seok Yoon, Young Rok Choi, Jae Yool Jang, Hanlim Choi, Jae Seong Jang, Seong Uk Kwon

Contents

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Surgery: Pancreas & Biliary

PO-051 Oncologic Impact of Monocarboxylate Transporter 4 (MCT4) in Pancreatic Cancer ························································································ 103Sung Hwan Lee, Chang Moo Kang, Ho Kyoung Hwang, Woo Jung Lee

PO-052 Comparison of the Prognosis of Endoscopic Retrograde Cholangiopancreatography Between Patients with Liver Cirrhosis vs Non-cirrhosis · 103Jae Min Lee, Hong Sik Lee, Jong Jin Hyun, Tae Hyung Kim, Jem Ma Ahn, Sun Young Yim, Yeon Seok Seo, Soon Ho Um, Chang Duck Kim, Ho Sang Ryu

PO-053 Life-threatening Hemobilia from a Ruptured Gastroduodenal Artery Pseudoaneurysm after Cholecystectomy: A Case Report ······················ 104Mara Teresa T. Panlilio, Mark Anthony A. De Lusong

PO-054 Intradutal Tubulopapillary Neoplasm of the Pancreas with an Associated Invasive Carcinoma ········································································ 104Woo Young Kim, Yu Ni Lee, Mi Jin Kim, Chan Kyun Park, Eun Young Kim

PO-055 Preoperative Volume-based PET Parameter, MTV2.5, As a Potential Surrogate Marker for Tumor Biology and Recurrence in Resected Pancreatic Cancer······················································································································································································································· 104

Sung Hwan Lee, Chang Moo Kang, Ho Kyoung Hwang, Sung Hoon Choi, Mi Jin Yun, Woo Jung Lee

PO-056 Living Donor Liver Transplantation for Diffuse Biliary Papillomatosis ··············································································································· 105Hyung Woo Park, Yang Won Nah, Chang Woo Nam

HBV (III)

PO-057 Baseline Quantitative HBsAg Level is Predictive of Virologic Response in Entecavir Treated Patients ······························································· 105Ju-Yeon Cho, Joon Hyeok Lee, Won Sohn, Dong Hyun Sinn, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo

PO-058 Quantitative Hepatitis B Surface Antigen and Hepatitis B Virus DNA Levels for Predicting Treatment Response to Tenofovir Therapy in Chronic Hepatitis B ························································································································································································· 105Sun Young Shin, Joo Ho Lee, Yun Bin Lee, Hana Park, Seong Gyu Hwang, Gyu Seong Rim

PO-059 Kinetics of Serum Hepatitis B Surface Antigen During the First Year of Tenofovir Treatment in Patients with Chronic Hepatitis B ················· 106Soon Sun Kim, Sun Young Park, Joo Han Park, Choong Kyun Noh, Hyo Jung Cho, Jae Young Cheong, Sung Won Cho

PO-060 Expressions of Hepatocyte HBcAg and HBsAg as a Marker in the Management of Chronic Hepatitis B Patients ············································ 107Sun Young Yim, Tae Hyung Kim, Jemma Ahn, Eun Sun Kim, Bora Keum, Yeon Seok Seo, Yoon Tae Jeen, Hong Sik Lee, Hoon Jai Chun, Soon Ho Um, Chang Duck Kim, Nam Hee Won, Ho Sang Ryu

PO-061 Comparison of Efficacy between Tenofovir and Entecavir in Treatment Naive Chronic Hepatitis B Patients ··················································· 108Sung Won Lee, Jung Hyun Kwon, Jain Lee, Nam Ik Han, Young Woon Kim, Soon Woo Nam, Kyu Won Chung, Jeong Won Jang

PO-062 Comparison of Tenofovir-based Therapy versus Lamivudine Plus Adefovir Combination Therapy in Patients with Lamivudine-Resistant Chronic Hepatitis B: Propensity Score Analysis ····························································································································································· 108Mu-yeol Lee, Jung Woo Shin, Sungsoo Byun, Bo Ryung Park, Min-Ho Kim, Chang Jae Kim, Byung Uk Lee, Jae Ho Park, Byung Gyu Kim, Seok Won Jung, In Du Jeong, Sung-Jo Bang, Neung Hwa Park

HCV

PO-063 All-Oral Dual Combination of Daclatasvir Plus Asunaprevir Compared with Telaprevir Plus Peginterferon-Alfa/Ribavirin in Chronic HCV Genotype 1b-Infected Treatment-Naive Japanese Patients ·············································································································································· 108Y. Karino, F. Suzuki, Y. Suzuki, J. Toyota, K. Chayama, Y. Kawakami, S. Fujiyama, T. Ito, Y. Itoh, E. Tamura, T. Ueki, H. Ishikawa, M. Linaberry, E.A. Hughes, H. Kumada

PO-064 Elderly and Cirrhotic Patients without Baseline NS5A Polymorphisms In HCV Genotype 1b Have Very High SVR to Daclatasvir Plus Asunaprevir······················································································································································································································· 109

F. McPhee, Y. Suzuki, J. Toyota, Y. Karino, K. Chayama, Y. Kawakami, H. Ishikawa, R. Bhore, N. Zhou, D. Hernandez, P. Mendez, H. Kumada

PO-065 All-Oral, Fixed-Dose Combination Therapy with Daclatasvir/ Asunaprevir/Beclabuvir for Patients with Chronic HCV Genotype 1 Infection without Cirrhosis: Unity-1 Phase 3 Results ··································································································································································· 110F. Poordad, W. Sievert, L. Mollison, N. Brau, J. Levin, T. Sepe, S. Lee, N. Boyer, J-P. Bronowicki, I.M. Jacobson, N. Boparai, E.A. Hughes, E.S. Swenson, P.D. Yin on behalf of the UNITY-1 Study Team

PO-066 Direct Medical Cost for Hepatitis C Virus Infection in South Korea, 2009-2013 ······························································································ 110Moran Ki, Hwa Young Choi, Eun Sun Jang, Sook-Hyang Jeong

PO-067 Acute Hepatitis and Reactivation of Hepatitis C Virus in Cancer Patients Receiving Systemic Chemotherapy ················································· 110Hae Lim Lee, Si Hyun Bae, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon

xxvi

PO-068 Genotype-Dependent Regulation of HCV Replication by Host Kinases ············································································································ 111Seungtaek Kim, Kwang-Hyub Han, Sang Hoon Ahn

Cirrhosis / Liver Fibrosis (II)

PO-069 Change of Fibrosis Pattern after Autologous Bone Marrow Cell Infusion in Patients with Advanced Liver Cirrhosis ······································· 111Ja Kyung Kim, Young Nyun Park, Jung Il Lee, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Kwan Sik Lee

PO-070 Expression of S100B During Hepatofibrogenesis by Bile Duct Ligation in C57BL/6mice ·················································································· 112Ji Won Park, Mo Jong Kim, Sung Eun Kim, Yong Chul Jeon, Myoung Kuk Jang, Dong Joon Kim, Choong Kee Park, Eun Kyoung Choi, Yong Sun Kim

PO-071 The Role of Beclin 1 During Epithelial Mesenchymal Transition in Liver Fibrosis ······························································································ 112Sung Woo Kim, Seung Kew Yoon

PO-072 Essential Roles of Focal Adhesion Kinases (FAK and PYK2) in TGF- -mediated Fibrogenic Signaling in Hepatic Stellate Cell ··························· 112So Hee Kang, Su Hyun Park, Sera Yang, Jung Hee Kim, Won Sohn, Ju Yeon Cho, Geum Youn Gwak, Byung Chul Yoo, David Brenner, Jonghwa Kim, Yong-Han Paik

PO-073 Sub-cirrhotic Range of Liver Stiffness Assessed Using Transient Elastography is Associated with a Decreased Risk of Hepatocellular Carcinoma Among Patients with HBV-related Cirrhosis ································································································································································· 113Mi Young Jeon, Hye Won Lee, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han

PO-074 Both Elevation of Hepatic Venous Pressure Gradient and Liver Stiffness can predict the Poor Long-term Mortality in Non-critically ill Patients with Cirrhosis ·········································································································································································································· 113Jae Yoon Jeong, Sun Min Kim, Tae Yeob Kim, Joo Hyun Sohn, Ji Yeoun Kim, Yongsoo Kim, Jinoo Kim, Woo Kyoung Jeong

Liver Transplantation / Others (I)

PO-075 The Model for Predicting Survival after Liver Transplantation ·························································································································· 113Dong Hyeon Lee, Yoon Jun Kim, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh, Jung-Hwan Yoon

PO-076 ABO Incompatible Living Donor Liver Transplantation Using Rituximab without Antibody Removal ······························································· 114Seung Duk Lee, Seong Hoon Kim, Eung Chang Lee

PO-077 Efficacy and Safety of Prophylaxis with Entecavir or Tenofovir and Hepatitis B Immunoglobulin in Preventing Hepatitis B Recurrence after Liver Transplantation ······························································································································································································· 114Young Mi Hong, Ki Tae Yoon, Mong Cho, Dae Hwan Kang, Hyung Wook Kim, Cheol Woong Choi, Su Bum Park, Jeong Heo, Hyun Young Woo, Won Lim

PO-078 Combination of Pegylated-interferon and Ribavirin as a Treatment after Liver Transplantation for Recurrent Hepatitis C virus : Single Center Experience with High Virological Response ······································································································································································· 114Young Mi Hong, Ki Tae Yoon, Mong Cho, Dae Hwan Kang, Hyung Wook Kim, Cheol Woong Choi, Su Bum Park, Jeong Heo, Hyun Young Woo, Won Lim

PO-079 A Rare Infectious Complication after LDLT; Pyogenic Spondylodiscitis Casued by Methicillin-resistant Staphylococcus aureus (MRSA) ·········· 115Joo Seop Kim, Doo Jin Kim, Tae You, Jang Yong Jeon

PO-080 Appearance and Clinical Characteristics of Contrast Enhanced Ultrasonography in Pyogenic Liver Abscess ··················································· 115Baek Gyu Jun, Sae Hwan Lee, Hong Soo Kim, Sang Gyune Kim, Young Seok Kim, Boo Sung Kim, Soung Won Jeong, Jae Young Jang, Young Don Kim, Gab Jin Cheon

PO-081 Plasma Cell Hepatitis following Liver Transplantation ······································································································································ 116Jung Hyun Kwon, Ibrahim Hanouneh, Daniela Allende, Lisa Yerian, Teresea Diago Uso, Bijan Eghtesad, Nizar N. Zein

Liver Transplantation / Others (II)

PO-082 RIP1 and RIP3 Inhibition Aggravates Hepatic Ischemic Reperfusion Injury ······································································································· 116Waqar Khalid Saeed, Dae Won Jun

PO-083 Effect of G-CSF on Mouse Hepatic Ischemic Reperfusion Injury Model ··········································································································· 116Waqar Khalid Saeed, Dae Won Jun

PO-084 Long Term Follow-up of Budd Chiari Patients Undergoing TIPS ······················································································································ 117Sonavane Amey, Amarapurkar Deepak

PO-085 Hepatectomy for Primary Hepatolithiasis ························································································································································· 117Hirak Pahari, Wei-Feng Li, Chih-Chi Wang, Ting-Lung Lin, Shih-Ho Wang, Chih-Che Lin, Yueh-Wei Liu, Chee-Chien Yong, Tsan-Shiun Lin, Allan M. Concejero, Chao-Long Chen

PO-086 Depression and Self-Care Compliance in Patients with Chronic Hepatic Disease ···························································································· 117Eun Hee Park, Si Hyun Bae

Contents

xxvii

Liver Cancer, Clinical (II)

PO-087 Correlation of MR and Pathologic Findings of the Indeterminate Small ( 3 cm) Hepatic Lesions in Chronic Liver Disease ····························· 118Seung Kak Shin, Yun Soo Kim, Eui Joo Kim, Su Young Kim, Young Sup Shim, Seung Joon Choi, Dong Hae Jung, Oh Sang Kwon, Duck Joo Choi, Ju Hyun Kim

PO-088 Survival Analysis of Re-hepatectomy Versus Re-radiofrequency Ablation for Intrahepatic Recurrence after Initial Hepatectomy or Radiofrequency Ablation for Hepatocellular Carcinoma ··························································································································································· 118Minjong Lee, Joon Yeul Nam, Sohee Oh, Young Youn Cho, Jeong-Ju Yoo, Yuri Cho, Dong Hyeon Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Nam-Joon Yi, Jeong Min Lee, Kwang-Woong Lee, Jung-Hwan Yoon, Kyung-Suk Suh, Hyo-Suk Lee, Yoon Jun Kim

PO-089 Optimal Interval Between On-demand Transarterial Chemoembolization in Patients with Unresectable Hepatocellular Carcinoma ··············· 119Hyung-Don Kim, Kang Mo Kim, Jihyun An, Han Chu Lee, Hyun-Ki Yoon, Gi-young Ko, Ji Hoon Shin, Dong Il Gwon, Kyu-Bo Sung, Jin Hyoung Kim

PO-090 Prognostic Factors for Complete Response and Recurrence after Transarterial Chemoembolization in Hepatocellular Carcinoma ················· 119Shin Ok Jeong, Eui Bae Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim, Yong Jae Kim, Suyeon Park, Young Ok Kim

PO-091 Transarterial Chemoembolization Contributed Survival Gain Following Combined Chemoradiation Therapy for Advanced Hepatocellular Carcinoma······················································································································································································································· 120

Ja Kyung Kim, Jung Il Lee, Jun Won Kim, Ik Jae Lee, Seung-Moon Joo, Kwang Hoon Lee, Eun Suk Cho, Tae Joo Jeon, Kwan Sik Lee

Liver Cancer, Basic (I)

PO-092 ACT Promotes Hepatocellular Carcinoma Growth and Metastasis through the mTORC1 and -Catenin Signaling Pathways ························· 120Hua Li, Mi-Jin Lee, Goung-Ran Yu, Seong-Hun Kim, Xue-Ji Han, Dae-Ghon Kim

PO-093 Attenuation of Liver Tumor Initiating Cells Reduces Migration and Metastasis via Regulation of ELK3/Net Expression ··································· 120Joon Ho Lee, Sung Woo Hong, Wonhee Hur, Jung-Hee Kim, Jung Eun Choi, Sung Min Kim, Eun Byul Lee, Seung Kew Yoon

PO-094 Mechanism of Synergistic Effect of Sorafenib and Celecoxib on Inducing Apoptosis in Hepatocellular Carcinoma Cell PLC/PRF/5 ················· 121Sera Yang, So Hee Kang, Su Hyun Park, Jung Hee Kim, Won Sohn, Ju Yeon Cho, Geum-Youn Gwak, Byung Chul Yoo, Jonghwa Kim, Yong-Han Paik

PO-095 Emodin Enhanced Radiation Killing Effect of Hepatocellular Carcinoma in Vitro and in Vivo ·········································································· 121Sang Youn Hwang, Jung Woo Im, Ki Jeong Jeon, Seon-Mi Lee, Hyun-Cheol Kang, Cheol Won Choi, Gwang Mo Yang, Seong Hak Chun, Kyu Heo

PO-096 Plasma MicoRNA-122 Level as a Predictive Marker for Treatment Response After Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma ······································································································································································································· 122Soon Sun Kim, Hyo Jung Cho, Ji Sun Nam, Joo Han Park, Choong Kyun Noh, Je Hwan Won, Jae Ik Bae, Sung Won Cho, Jae Youn Cheong

PO-097 Double Primary Intrahepatic Cholangiocarcinoma and Adrenal Metastases of Hepatocellular Carcinoma: A Case Report ······························ 122Adianto Nugroho, Kwang-Woong Lee, Hyo-Shin Kim, Hyeyoung Kim, Nam-Joon Yi, Kyung-Suk Suh

Liver Cancer, Basic (II)

PO-098 Filamin B Acts as a Tumor Suppressor for Hepatocellular Carcinoma in Hypoxic Conditions by Activating the JNK Pathway ·························· 122Hongkeun Ahn, Yuri Cho, Dong Hyeon Lee, Minjong Lee, Jeong-ju Yoo, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon

PO-099 Role of Bile Acid-induced Fibroblast Growth Factor 19 Expression in Hepatocellular Carcinoma Proliferation ················································ 123Dong Hyeon Lee, Young Chang, Yuri Cho, Jung-Ju Yoo, Minjong Lee, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

PO-100 Correlation Analysis of Discoidin Domain Receptor 2 Expression and Prognosis of Hepatocellular Carcinoma after Surgical Resection ·········· 123Seon A Kim, Joong Won Park, Bo Hyun Kim, Seong Hoon Kim, Eun Kyung Hong

PO-101 S100A8/9 Overexpression by the JNK Pathway is Involved in Inflammation-associated Hepatocarcinogenesis Under Hypoxic Conditions ······ 123Yuri Cho, Hyeki Cho, Dong Hyeon Lee, Minjong Lee, Jeong-ju Yoo, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon

PO-102 Inhibition of Cell Proliferation and Anti-apoptotic Effect by Suppression of ADMA17 Expression in Hepatocellular Carcinoma Cells ············· 124Sung Woo Hong, Wonhee Hur, Joon Ho Lee, Jung Eun Choi, Jung Hee Kim, Sung Woo Kim, Sung Min Kim, Eun Byul Lee, Seung Kew Yoon

PO-103 ERTC Involved in HCC Growth and Metastasis Through p53 Signaling Pathway ····························································································· 124Hua Li, Mi-Jin Lee, Goung-Ran Yu, Lan Liu, Xue-Ji Han, Dae-Ghon Kim

xxviii

Poster Exhibition

Cirrhosis / Liver Fibrosis

PE-001 Reproducibility of Point Shear Wave Elastography (PSWE) in the Evaluation of Liver Elasticity ········································································ 127Maria Regina Cruz-Tuble

PE-002 A Case of Spontaneous Bacterial Empyema in Liver Cirrhosis with Recovery after the Closed Thoracostomy and Antibiotics Treatment ······· 127Jeong Hwan Cho, Chang Su Kim, Jin Woo Koh, Hyun Gwang Jung, Jae Choon Pang, Guk Sang Han, Chae Ryeong Jang

PE-003 Thyroid Function Abnormality in Patients with Liver Cirrhosis ························································································································· 127Dipendra Raj Pandeya, Bibek Bhatta, Yogesh Bhatta

PE-004 Protective Effect of Clusterin on Hepatic Fibrosis ············································································································································ 128Hye-Young Seo, Yun-A Jung, Eun-Ju Lee, Keun-Gyu Park, In- Kyu Lee, Mi-Kyung Kim, Byoung Kuk Jang

PE-005 Comparison of the Accuracy between Liver and Spleen Elastography Using Acoustic Radiation Force Impulse and Other Noninvasive Tests in Predicting the Presence of Esophageal Varices ································································································································································ 128Yang-Hyon Baek, Sang-Young Han, Sung-Wook Lee, Jin-Sook Jeong, Hee-Jin Kwon

PE-006 Head-to-head Comparisons between Collagen Proportionate Area and Acoustic Radiation Force Impulse Elastography in Liver Fibrosis Evaluation······················································································································································································································· 128

Sheng-Hung Chen, Cheng-Yuan Peng, Hsueh-Chou Lai, Jung-Ta Kao, Po-Heng Chuang, Wen-Pang Su, I-Ping Chiang

PE-007 The Accuracy of Ultrasonography for the Evaluation of Portal Hypertension in Patients with Cirrhosis: A Systematic Review ························ 129Yoo Li Lim, Soon Koo Baik, Moon Young Kim, Won Ki Hong, Sang Ok Kwon

PE-008 Clinical Features of Spontaneous Bacterial Peritonitis; Ten Years Single Center Experience ············································································ 129Ha Young Na, Jeong Han Kim, Soon Young Ko, Won Hyeok Choe, So Young Kwon

PE-009 Effectiveness of MELD, MELDNa, APRI, and FIB-4 as Predictors of Mortality and Development of HCC in Patients with Cirrhosis ·················· 129Ji Wan Kim, Jeong Han Kim, Soon Yong Ko, Won Hyeok Choe, So Young Kwon

PE-010 Difference of Polymerization Time of Cyanoacrylate according to the Concentration in Liver Cirrhosis Patients ············································· 130Jin Sil Pyo, Tae Hee Lee, Min Ji Park, A Reum Cho, Joo Ah Lee, Sun Hee Oh, Gi Hyun Ryu, Hoon Seop Koo, Kyoung Ho Song, Sun Moon Kim, Kyu Chan Huh, Young Woo Choi, Young Woo Kang

PE-011 Two Cases of Survived Spontaneous Intramuscular Hematoma in Liver Cirrhosis ··························································································· 130Gi Dae Kim, Heon Young Lee, Byung Seok Lee, Eaum Seok Lee, Jae Kyu Sung, Hee Seok Moon, Sun Hyung Kang, Gee Young Yun, Woo Sub Kim, Seok Hyun Kim

PE-012 Percutaneous Transhepatic Obliteration for Uncontrolled Rectal Variceal Bleeding : A Case Report ······························································· 130Su Hyun Lee, Se Young Jang, Sung Kyung Jang, Yu Rim Lee, Soo Young Park, Won Young Tak, Young Oh Kweon

PE-013 Regulation of Activated Hepatic Stellate Cells by Interferon- Gamma and 1-Methyl Tryptophan ···································································· 131Ji-Eun Oh, Soon Koo Baik, Young Woo Eom

PE-014 Two Cases with Regression of Esophageal Varices After Interferon-alpha Plus Ribavirin Therapy in Patients with Hepatitis C Virus-Related Liver Cirrhosis······················································································································································································································· 132

Soon Jae Lee, Yoo-Kyung Cho, Byung-Cheol Song

PE-015 Evaluation of Liver and Spleen Stiffness by ARFI in Noncirrhotic Portal Hypertension (NCPH) ········································································· 133Apurva Shah, Vaibhav Somani, Deepak Amarapurkar

PE-016 Relative Adrenal Insufficiency in Patients with Alcoholic Liver Cirrhosis ; Multicenter Study in Gangwon Province, Korea ······························ 133Young Don Kim, Dae Hee Choi, Ki Tae Suk, Moon Young Kim, Gab Jin Cheon, Soon Koo Baik, Dong Joon Kim

PE-017 Endovascular Interventions in the Treatment of Patients with Portal Hypertension ························································································· 134S. Borovskiy, T. Tuganbekov, N. Malayew, I. Ten, D. Tyo

PE-018 Application of Innovative Technologies in Correction of Portal Hypertension in Patients with Liver Cirrhosis ·················································· 134B. Abdrahmanov, D. Tyo

PE-019 Experience of Sorafenib Administration in Patients with Hepatocellular Carcinoma ························································································ 135D. Aribzhanov, K. Umarov

PE-020 Anti-fibrosis Effect of Urushiol (Rhus verniciflua Stokes) in Mice with Thioaceamide Induced Liver Fibrosis ···················································· 135Meegun Hong, Ki Tae Suk, Seungwoo Kim, Myong Jo Kim

Contents

xxix

Acute Liver Disease / Liver Failure

PE-021 Clinical, Virological Features and Outcome of Acute Hepatitis B in Korean Adults from 2005 to 2014: A Single-center Experience ··············· 135Myung Jin Oh, Jae Won Choi, Seung Hyun Lee

PE-022 Liver Stiffness Measurement (FibroScanR ) Determines the Risk of Recurrence after Radiofrequency for Early Staged Hepatocellular Carcinoma······················································································································································································································· 136

Soo Young Park, Se Young Jang, Won Young Tak, Young Oh Kweon, Na Ri You, Sun Kyung Jang, Yu Rim Lee, Su Hyun Lee, Keun Hur, Im Won, Hyun Young Woo, Jeong Heo, Jung Gil Park

PE-023 A Case of Multiple Pyogenic Liver Abscesses Caused by Microperforation of an Idiopathic Cecal Ulcer ························································· 136Dong Ho Jo, Dong Han Yeom, Ki Chang Sohn, Eun Young Cho, Min Su Chu, Haak Cheoul Kim

PE-024 Levocetirizine-induced Liver Injury ··································································································································································· 136Ja Kyung Kim, Moon Chan Jung, Ji Won Park, Sung Eun Kim, Choong Kee Park

PE-025 Fatal Allopurinol Hepatotoxicity in Patient with Alcoholic Liver Cirrhosis ········································································································· 137Jeong Ill Suh, Tae Ho Kwon

PE-026 Acute Ischemic Hepatitis Caused by Spinal Anesthesia-induced Hypotension ································································································· 137Jeong Ill Suh

PE-027 The Usefulness of Liver Fibrosis Index by Real Time Elastography in the Patients with Acute Hepatitis ··························································· 137Young Woon Kim, Soon Woo Nam, Jung Hyun Kwon, Eun Chung, Sung Won Lee, Jong-yul Lee, Jeong Won Jang, Kyu Won Chung

PE-028 LXR Agonist and Fenofibrate Combination Treatment Decreased Hepatic Inflammation in Non-alcoholic Fatty Liver Model ························ 138Min Young Kim, Dae Won Jun, Yi Seop Song, Tae Yeob Kim, Hyeon Tae Kang, Kiseok Jang, Chang Hong Lee, Jae Yoon Jeong, Joo hyun Sohn, Ho Hyun Nam, Wook Jin Lee

PE-029 Chronic Pancreatitis Associated with Liver Infarction and Pancreas Pseudoaneurysm : A Case Report ···························································· 138Yeon Oh Jeong, Sang Goon Shim, Chang Wook Chung

PE-030 Atypical Onset of Liver Injury Case Occurred by Bicalutamide ························································································································· 138Seok Won Kim, Heon Young Lee, Byung Seok Lee, Jae Kyu Sung, Eaum Seok Lee, Hee Seok Moon, Sun Hyung Kang, Ju Seok Kim, Sung Hoon Kang, Seok Hyun Kim

PE-031 Effects of Self-withdrawal of Antiviral Agents for Hepatitis B, Analyzing Acute on Chronic Liver Failure Patients Referred for Liver Transplantation······················································································································································································································· 139

Soonkyu Lee, Jong Young Choi, Seung Kew Yoon, Si Hyun Bae, Hyun Yang, Hae Lim Lee, Dong Goo Kim, Young Kyoung You, Ji Won Han, AngeloB Lozada

PE-032 A Case of Acute Hepatitis A with Prolonged Cholestasis and Acute Pancreatitis ···························································································· 139Min Ji Park, Tae Hee Lee, Sun Hee Oh, A Reum Cho, Joo Ah Lee, Young Woo Kang

PE-033 Liver Fetal Cell Therapy as a Promising Approach for Patients with End-Stage Liver Disease on the Waiting List ············································ 139Akhmet Seidakhmetov, Marlen Doskali, Myltykbay Rysmakhanov, Samat Saparbayev, Venera Rahmetova, Ainura Doszhan, Abay Baigenzhin, Zhaksylyk Doskaliyev

PE-034 Significant Factors for Prediction of 90-day Mortality in Korean Patients Who Were Admitted with Acute Decompensation of Chronic Liver Disease······················································································································································································································· 139

Eileen L. Yoon, Eunhee Choi, Tae Yeob Kim, Do Seon Song, Hee Yeon Kim, Young Kul Jung, Dong Hyun Sinn, Chang Wook Kim, Dong Joon Kim

PE-035 Acute Hepatitis A, B, C, and D in Mongolia ···················································································································································· 140Enkhamgalan Tuvshinbayar, Jantsansengee Baigalmaa, Tserendorj Chinbayar, Do Young Kim, Sang Hoon Ahn, Mohammed Eslam, Kwang-Huyb Han, Jacob George, Oidov Baatarkhuu

PE-036 Association of Liver Enzymes with Type 2 Diabetes Mellitus: Possibility of Pathological Marker ······································································ 140Shrestha Nirajan, Bhatt Nirmal Prasad, Dahal Sudimna, Shrestha Rojeet

PE-037 Association between Biliary Complication and Hepatic Hilum Approaches in Liver Resections ········································································ 141Natsagnyam Puntsagdulam

PE-038 Dyslipidemia in Liver Diseases: An Association for Better Management in Diabetic Patients ··········································································· 141Nirmal Prasad Bhatt, Nirajan Shrestha, Sudhimna Dahal, Rojeet Shrestha

Alcoholic / Metabolic / Genetic / Immunologic Liver Disease

PE-039 Diagnostic Value of Serum Gamma Glutamyl Transferase to Alkaline Phosphatase (GGT to ALP) Ratio in Patients with Alcoholic Liver Disease······················································································································································································································· 141

Prabin Gyawali, Rajshree Bhujel, Siddha BahadurRana Magar, Raj Kumar Shrestha, Ram Bahadur Gurung

PE-040 Comparison of Deritis Ratio with Pre-existing Scoring System to Assess Severity among Patients with Alcoholic Liver Disease ······················ 142Bhup Dev Bhatta, Mukund Kalouni, Umid Kumar Shrestha

xxx

PE-041 Bone Density in Adult Males with Non Alcoholic Fatty Liver Disease ··············································································································· 142Haejin Yang, Sang Goon Shim

PE-042 Nationwide, Population-based Epidemiology and Disease Burden of Autoimmune Hepatitis in South Korea ················································· 142Bo Hyun Kim, Hwa Young Choi, Moran Ki, Kyung-Ah Kim, Eun Sun Jang, Sook-Hyang Jeong

PE-043 Clinical Significance of Fatty Liver Disease Induced by Tamoxifen and Toremifene in Breast Cancer Patients ·················································· 143Young-Joo Yang, Kang Mo Kim, Hyung-Don Kim, Yeon-Jung Ha, Mi-Jung Jun, Jihyun An, Danbi Lee, Ju Hyun Shim, Young-Suk Lim, Han Chu Lee, Young-Hwa Chung, Yung Sang Lee

PE-044 Systemic Review: Steroid, Pentoxifylline and Combined Therapy for Severe Alcoholic Hepatitis ····································································· 143Young-Sun Lee, Ji Hoon Kim, Hyun Jung Kim, Yang Jae Yoo, Tae Suk Kim, Seong Hee Kang, Sang Jun Suh, Young Kul Jung, Yeon Seok Seo, Hyung Joon Yim, Jong Eun Yeon, Kwan Soo Byun

PE-045 Serum Cytokine Levels and Severity of Alcoholic Liver Disease ························································································································ 143Chan Ran You, Sang Wook Choi, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Jeong Won Jang

PE-046 The Relationship between Serum Osteocalcin and Non Alcoholic Fatty Liver Disease ······················································································ 144Haejin Yang, Sang Goon Shim

PE-047 Prevalence of and Factors Associated with Nonalcoholic Fatty Liver Disease in a Nonobese Korean Population ············································· 144Hyun Chin Cho, JI Eun Oh, Chang Uk Jeong, Dae Hyun Cho, Kil Jong Yu, Sang Goon Shim

PE-048 The Role of GGT as a Predictor of Alcoholic Liver Disease ······························································································································· 144Soo Yeon Jo, Soo Hyung Ryu, Mi Young Kim, Sung Won Park, Won Jae Yoon, Jeong Seop Moon

PE-049 Relation of Risk Factors Between Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in Young Adults ··············································· 145Kyoung Min Sohn, Youn Ju Jeon, Hajin Nam, Hye Jin Noh, Min Jung Kwon, Young Mook Kim

PE-050 Effect of Thioctic Acid in NAFLD Patients with Diabetes ·································································································································· 145Gi Hyun Kim, Jung Wha Chung, Eun Sun Jang, Sook-Hyang Jeong, Jin Wook Kim

PE-051 The Prevalence of Osteoporosis in Alcoholic Cirrhotic Patients: A Priliminary Data of Multicenter Study in Gangwon Province, South Korea ··· 145Tae S. Kim, Daehee Choi, Moon Y. Kim, Soon K. Baik, Ki-Tae Suk, Dong J. Kim, Young D. Kim, Gab J. Cheon

PE-052 Impact of Hypothyroidism on Development Non-alcoholic Fatty Liver Disease; 4-year Retrospective Cohort Study ········································ 146Kil Woo Lee, Yong Kyun Cho, Byung Ik Kim, Woo Kyu Jeon, Hong Ju Kim

PE-053 Alcoholic Fatty Liver Disease and the Metabolic Syndrome ····························································································································· 146Ki Bae Bang, Yong Kyun Cho, Byung Ik Kim, Woo Kyu Jeon, Hong Joo Kim

Cell Biology / Molecular Biology

PE-054 Direct Conversion of Mouse Fibroblasts into Functional Integration-free Hepatocyte-like Cells ······································································ 146Jonghun Kim, Kyung Tae Lim, Seung Chan Lee, Dong Wook Han

PE-055 Direct Conversion of Fibroblasts into Bipotent Hepatic Stem Cells by Defined Factors ···················································································· 147Jung Hyun Im, Kyung Tae Lim, Dong Wook Han

PE-056 Spectrum of Proteins Expression in the Liver Tissue and Cell Isolates in Chronic Liver Injury Model ································································ 147Prabodh Risal

PE-057 Palmitic Acid Induced Apoptosis via Inhibition of Autophagy in Hepatocytes ·································································································· 147Eun-Ju Lee, Hye-Young Seo, Yun-A Jung, Woo Jin Chung, Jae Seok Hwang, Mi-Kyung Kim, Byoung Kuk Jang

PE-058 Fermented Soymilk Prevent Free Fatty Acid-Induced Lipogenesis and Production of Reactive Oxygen Species in Hepatocellular Steatosis Model······················································································································································································································· 148

Sang Bong Ahn, Byoung Kwan Son, Wen Hao Wu, Jong Hun Lee, Ji Hyun Kim, Seong Yong Kim, Jin Hyun Jun

PE-059 Dickkopf-1 Enhances Tumor Angiogenesis and Endothelial Mesenchymal Transition ····················································································· 148Sung Hoon Choi, Hyun Gyu Lee, Hyemi Kim, Wonseok Kang, Jun Young Park, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Seung Up Kim

PE-060 Hepatic Inflammatory Mediator Sphingosine-1-phosphate is Fibrogenic in Hepatic Stellate Cell Via Hippo-YAP Signaling Pathway ··············· 148Su Hyun Park, So Hee Kang, Se Ra Yang, Jung Hee Kim, Won Sohn, Ju Yeon Cho, Geum-Youn Gwak, Byung Chul Yoo, Jonghwa Kim, Yong Han Paik

PE-061 Isolation of Human Hepatocytes by A Two-Step Collagenase Perfusion Procedure from Cirrhotic Liver ························································· 149Saltanat Ualiyeva, B. Umbayev, A. Donbay, S. Askarova

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PE-062 The Combined Effect of Stem Cell Factor and Granulocyte Macrophage Colony-stimulating Factor Administration after 90% Partial Hepatectomy in Rats Using Modified Ligation Technique ····················································································································································· 149Dasom Choi, Yunsung Seo, Seung Duk Lee

Hepatitis B, Anti-viral Therapy

PE-063 In Vitro Susceptibility Test of Tenofovir in Hepatitis B Virus Refractory to Entecavir-Adefovir Combination ···················································· 150Jeong Han Kim, Soon Young Ko, Won Hyeok Choe, So Young Kwon

PE-064 Treatment Efficacy of Tenofovir in Treating Drug-Resistant Chronic Hepatitis B ····························································································· 150Jong Seok Joo, Ju Seok Kim, Hae Jin Shin, Ki Dae Kim, Eaum Seok Lee, Seok Hyun Kim, Heon Young Lee, Byung Seok Lee

PE-065 The Correlation between Hepatitis B Surface Antigen Titer and Liver Stiffness in Treatment Naïve Chronic Hepatitis B Patients ···················· 150Seung Suk Baek, Eileen L. Yoon, Wook Hyun Yeo, Hyung Gy Bae, Yu Ri Hwang, So Young Ahn, Ji Young Park, Jung Min Choi, Tae Joo Jeon, Won Chang Shin, Won-Choong Choi

PE-066 HBV-DNA and Clinical Characteristics of Patients Who Developed HCC while Receiving Tenofovir Disoproxil Fumarate (TDF) Following 8 Years of Therapy ··········································································································································································································· 151W. Ray Kim, Rohit Loomba, Thomas Berg, Raul Aguilar Schall, Leland J. Yee, Phillip Dinh, John F. Flaherty, Eduardo B. Martins, Terry Therneau, Ira Jacobson, Scott Fung, Selim Gurel, Maria Buti, Patrick Marcellin

PE-067 Long Term Treatment with TDF is Well Tolerated and Associated with Durable Virologic Response with No Detectable Resistance ·············· 151Patrick Marcellin, Edward J. Gane, Robert Flisiak, Huy N.Trinh, Joerg Petersen, Selim Gurel, Kelly D. Kaita, Iskren A. Kotzev, Naoky Tsai, John F. Flaherty, Raul E. Aguilar Schall, Kathryn M. Kitrinos, Mani Subramanian, John G. McHutchison, Jacob George, Harry L. Janssen, Jin Youn, Maria Buti

PE-068 HCC Risk Scores: Application of the CU-HCC, GAG-HCC and PAGE-B Scores to Chronic Hepatitis B Patients Treated with TDF ··················· 151W. Ray Kim, Rohit Loomba, Thomas Berg, Raul Aguilar Schall, Leland J. Yee, Phillip Dinh, John F. Flaherty, Eduardo B. Martins, Terry Therneau, Ira Jacobson, Scott Fung, Selim Gurel, Maria Buti, Patrick Marcellin

PE-069 Efficacy of Switching from Adefovir to Tenofovir in Chronic Hepatitis B Patients with a Suboptimal Response to Adefovir- based Combination Rescue Therapy due to Nucleoside Analogue Resistance (SATIS Study) ······················································································································· 152Hye Won Lee, Jun Yong Park, Kyu Sik Jung, Wonseok Kang, Beom Kyung Kim, Seung Up Kim, Do Young Kim, Kwang-Hyub Han, Sang Hoon Ahn

PE-070 The Result of Complete Virological Response of Tenofovir Dipivoxil Fumarate Monotherapy for Nucleos(t)ide Analogue Naïve and Nucleos(t)ide Analogue Experienced Chronic Hepatitis B Patients ········································································································································ 152Sun Hee Oh, Tae Hee Lee, Min Ji Park, A Reum Cho, Joo Ah Lee, Ki-Hyun Ryu, Hoon Sup Koo, Kyung Ho Song, Sun Moon Kim, Kyu Chan Huh, Young Woo Choi, Young Woo Kang

PE-071 Comparing Efficacy of Entecavir and Tenofovir in Treatment Naïve Chronic Hepatitis B Patients in Korea ······················································ 153Kyu Sik Jung, Hye Won Lee, Goo Hye Jin, Beom Kyung Kim, Seung Up Kim, Jun Yong Park, Do Young Kim, Kwang-Hyub Han, Sang Hoon Ahn

PE-072 Adefovir-associated Fanconi Syndrome Presenting as Repeated Multiple Pathologic Bone Fracture due to Hypophosphatemic Osteomalacia · 153So Jung Yeo, Baek Gyu Jun, Sae Hwan Lee, Hong Soo Kim, Sang Gyune Kim, Young Seok Kim, Boo Sung Kim, Soung Won Jeong, Jae Young Jang, Young Don Kim, Gab Jin Cheon

PE-073 Clinical Response to Tenofovir Monotherapy in Korean Chronic Hepatitis B Patients ······················································································ 154Eun-Hyung Yoo, Tae Hee Lee, Young Woo Kang, Hyun-Jung Cho

PE-074 Delayed Serologic Response in Multi-drug Resistant CHB Patients with Tenofovir and Entecavir Combination Therapy in Real Practice ········· 154Sung Won Lee, Jung Hyun Kwon, Jain Lee, Nam Ik Han, Young Woon Kim, Soon Woo Nam, Kyu Won Chung, Jeong Won Jang

PE-075 The Hypersensitivity Skin Reaction in Chronic Hepatitis B Patient Treated with Tenofovir Disoproxil Fumarate ··············································· 154Mi Young Kim, Soo Hyung Ryu, Soo Yeon Jo, Sung Won Park, Won Jae Yoon, Jeong Seop Moon

PE-076 Regression of Esophageal Varices During Entecavir Treatment in Patients with Hepatitis B Virus-related Liver Cirrhosis ································· 155Hye Young Jwa, Yoo-Kyung Cho, Eun Kwang Choi, Heung Up Kim, Hyun Joo Song, Soo-Young Na, Sun-Jin Boo, Seung Uk Jeong, Bong Soo Kim, Byoung-Wook Lee, Byung-Cheol Song

PE-077 Efficacy of Entecavir in Patients with Chronic Hepatitis B with High Baseline Viral Load ················································································· 155Sungsoo Byun, Mu-yeol Lee, Jung Woo Shin, Bo Ryung Park, Min-Ho Kim, Chang Jae Kim, Byung Uk Lee, Jae Ho Park, Byung Gyu Kim, Seok Won Jung, In Du Jeong, Sung-Jo Bang, Neung Hwa Park

PE-078 The Effect of Telbivudine Therapy on Serum Creatine Kinase Levels in Patients with Chronic Hepatitis B ······················································· 155Ali Pekcan Demiroz, Cigdem Ataman Hatipoglu, Cemal Bulut, Nesrin Ata, Esra Kaya Kilic, Sami Kinikli, Ali P. Demiroz

PE-079 Safety and Efficacy of Tenofovir Disoproxil Fumarate in Patients with Chronic Hepatitis B between Decompensated and Compensated Cirrhosis······················································································································································································································· 156

Myeong Jun Song, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Byung Seok Lee, Tae Hee Lee, Suk Bae Kim, Hee Bok Chae, Il soon Jeong, Soon Young Ko

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Hepatitis B, Others

PE-080 Prevalence and Risk Factors of Hepatitis B Surface Antigen Carriage in Central Nepal: A Hospital based Study ············································· 156Dhruba Acharya, Bikash Bogati, Sarita Bhandari, Kabita Kuikel

PE-081 Role of IL28B Polymorphisms in the Treatment Response of Entecavir in Treatment Naïve Chronic Hepatitis B Patients ································· 157Hyoung Su Kim, Ji Won Park, Sung Eun Kim, Ki Tae Suk, Myoung Kuk Jang, Sang Hoon Park, Dong Joon Kim, Myung Seok Lee, Choong Kee Park

PE-082 A Case of Hepatic Decompensation in Pregnant Woman with Chronic Hepatitis B ························································································ 157Hanra Koh, Chung Hwan Jun, Eunae Cho, Sung Kyu Choi

PE-083 Clonal Analysis of Full-length Genome and Characterization of Surface Antigenicity of Entecavir-resistant Hepatitis B Virus Isolated from Chronic Hepatitis B Patients ························································································································································································· 158So Ree Park, Eun-Sook Park, Yong Kwang Park, Sung Hyun Ahn, Doo Hyun Kim, Ah Ram Lee, Hong Seok Kang, Kyun-Hwan Kim

PE-084 The Substitution at rt269 in Hepatitis B Virus Polymerase Is Associated with the Multi-drug Resistance as a Compensatory Mutation ·········· 158Ah Ram Lee, Sung Hyun Ahn, Doo Hyun Kim, Yong Kwang Park, Eun-Sook Park, Gu-Choul Shin, Soree Park, Hong Seok Kang, Kyun-Hwan Kim

PE-085 The Impact of the Hepatitis B Virus Polymerase rtA181T Mutation on Replication and Drug Resistance Is Potentially Affected by Overlapping Changes in Surface Gene ······························································································································································································· 158So Ree Park, Sung Hyun Ahn, Yong Kwang Park, Eun-Sook Park, Doo Hyun Kim, Ah Ram Lee, Hong Seok Kang, Kyun-Hwan Kim

PE-086 Processing of c-FLIP Is Involved in TNF-a-mediated Suppression of HBV ·········································································································· 159Yong Kwang Park, Eun-Sook Park, Sung Hyun Ahn, Doo Hyun Kim, Ah Ram Lee, So Ree Park, Hong Seok Kang, Kyun-Hwan Kim

PE-087 Risk Factors for HBV Reactivation in Patients Underwent Hematopoietic Stem Cell Transplantation in HBV Endemic Area ···························· 159Hyung Min Yu, Chung Hwan Jun, Sung Kyu Choi, EunAe Cho

PE-088 Profile of Patients Diagnosed with Fatty Liver Disease at Seamen's Hospital ··································································································· 159Alfonso Syoei R. Yoshida, Leilanie A. Nicodemus

PE-089 Men Seropositive for Hepatitis B Surface Antigen Are at Risk of Lower Bone Mineral Density: the 2008-2010 Korea National Health and Nutrition Examination Surveys ························································································································································································ 160Myong Ki Baeg, Seung Kew Yoon, Sun-Hye Ko, Kyung-Do Han, Si Hyun Bae, Jong Young Choi, Myung-Gyu Choi

PE-090 Viral Hepatitis: A Bug of Increasing Concern ··················································································································································· 160Bibek Bhatta, Yogesh Bhatta

Hepatitis C

PE-091 HCV ················································································································································································································ 161Sung Soo Kim, Jyothi K.R., Su Hui Yang, Won-Jea Cho

PE-092 The Significance of Change of Mean Corpuscular Volume (MCV) During Treatment of Chronic Hepatitis C ·················································· 161Eun Young Cho, Haak Cheoul Kim, Young Bum Cho, Min Soo Joo, In Hee Kim

PE-093 Development of Novel Infectious Clones of Genotype 1 Hepatitis C Virus ······································································································ 161Bora Jin, Aeri Chung, Kwang-Hyub Han, Seungtaek Kim, Sang Hoon Ahn

PE-094 Safety and Efficacy Outcomes of All-oral Daclatasvir-Containing Regimens in Patients with or without Cirrhosis in Phase 2 and 3 Studies ··· 161D.M. Jensen, I.M. Jacobson, H. Kumada, J. Toyota, M. Sulkowski, M. Manns, J.H. Kao, J. Heo, P.D. Yin, P. Mendez, E.A. Hughes, S. Noviello

PE-095 100% SVR12 in Japanese Patients with Chronic GT1 HCV Infection Receiving Ledipasvir/Sofosbuvir for 12 Weeks: A Multicenter Phase 3 Study······················································································································································································································· 162

Masashi Mizokami, Tetsuo Takehara, Osamu Yokosuka, Naoya Sakamoto, Masaaki Korenaga, Hitoshi Mochizuki, Kunio Nakane, Hirayuki Enomoto, Mikio Yanase, Hidenori Toyoda, Fusao Ikeda, Takuya Genda, Takeji Umemura, Hiroshi Yatsuhashi, Tatsuya Ide, Nobuo Toda, Kazushige Nirei, Yoshiyuki Ueno, Yoichi Nishigaki, Juan Betular, Bing Gao, Akinobu Ishizaki, Masa Omote, SunJin Hwang, Phillip S. Pang, Steven J. Knox, William T. Symonds, John G. McHutchison, Namiki Izumi, Masao Omata

PE-096 97% SVR in Japanese Patients with Chronic GT2 HCV Infection Receiving Sofosbuvir + Ribavirin for 12 Weeks: A Phase 3 Study ················ 163Masao Omata, Shuhei Nishiguchi, Yoshiyuki Ueno, Hitoshi Mochizuki, Namiki Izumi, Fusao Ikeda, Hidenori Toyoda, Osamu Yokosuka, Kazushige Nirei, Takuya Genda, Takeji Umemura, Tetsuo Takehara, Naoya Sakamoto, Yoichi Nishigaki, Kunio Nakane, Nobuo Toda, Tatsuya Ide, Mikio Yanase, Keisuke Hino, Juan Betular, Bing Gao, Aki-nobu Ishizaki, Masa Omote, Diana M. Brainard, SunJin Hwang, Steven J. Knox, William T. Symonds, John G. McHutchison, Hiroshi Yatsuhashi, Masashi Mizokami

PE-097 Health-Related Quality of Life in Patients Infected with Hepatitis C Virus in South Korea ··············································································· 163Eun Sun Jang, Young Seok Kim, Kyung-Ah Kim, Youn Jae Lee, Woo Jin Chung, In Hee Kim, Byung Seok Lee, Sook-Hyang Jeong

PE-098 MicroRNA-451 Modulates Hepatitis C Virus Replication through the Hepatic Lipid Metabolism ····································································· 164Eun Byul Lee, Jung-Hee Kim, Wonhee Hur, Seung Kew Yoon

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PE-099 Depression in Chronic Hepatitis C: Prevalence and Incidence during Antiviral Therapy ··················································································· 164Joo Yeong Baeg, In Hee Kim, Seung Young Seo, Young Seok Kim, Eun Uk Jung, Junhyeon Cho, Jung Wha Chung, Eun Sun Jang, Jin Wook Kim, Sook-Hyang Jeong

PE-100 Sofosbuvir Population Pharmacokinetics in Korean Subjects with Chronic Genotype 2 HCV Infection ··························································· 164Brian Kirby, Lingling Han, Diana M. Brainard, Steven J. Knox, K-H John Ling, Jin Youn, Anita Mathias

PE-101 Population Pharmacokinetic Analysis of Ledipasvir/Sofosbuvir Fixed Dose Combination Tablet in Korean Subjects with Chronic Genotype 1 HCV Infection ·········································································································································································································· 165Kimberly L Garrison, Polina German, Bing Gao, Phillip S. Pang, Steven J. Knox, John Ling, Jin Youn, Anita Mathias

PE-102 Clinical Features and Outcomes of Patients with Hepatitis C Virus Genotype 3 in Korea ················································································ 165Ra Ri Cha, Sang Soo Lee, Ja Yun Choi, Yun Won Jo, Hye Won Oh, Cha Young Kim, Jin Joo Kim, Jae Min Lee, Hong Jun Kim, Hyun Jin Kim, Tae Hyo Kim, Woon Tae Jung, Ok Jae Lee

PE-103 Regional Differences of HCV Genotype in Jeollanam-do Province ··················································································································· 166Kyung Lee Kim, Chung Hwan Jun, Sung Kyu Choi, EunAe Cho

PE-104 Clinical Characteristics of Chronic Hepatitis C in the Elderly Patients ·············································································································· 166Eunae Cho, Kyung Lee Kim, Sung Kyu Choi, Chung Hwan Jun

PE-105 Factors Related to Effective Treatment for Aged Patients with Chronic Hepatitis C with Pegylated Interferon and Ribavirin Combination Therapy······················································································································································································································· 166

Soon Young Ko, Tae Hee Lee, Suk Bae Kim, Hong Soo Kim, Baek Gyu Jun, An Na Kim, Ji Woong Jang, Myeong Jun Song, Jeong Rok Lee, Tae Young Jung, Byung Seok Lee, Hee Bok Chae

PE-106 Hepatitis C Virus Suppresses Interferon-stimulated Production of Immunoproteasomes by the Protein Kinase R Pathway ····························· 167In Soo Oh, Wonseok Kang, Pil Soo Sung, Ulrike Seifert, Hyung Joon Kim, Eui-Cheol Shin

PE-107 Interleukin-28B Polymorphisms and Response of Peg-IFN/ Ribavirin Treatment in Chronic Hepatitis C Patients ·············································· 167Syifa Mustika, Bogi Pratomo Wibowo, Juniastuti, Maria Inge Lusida

PE-108 Clinical and Economic Outcomes of Treating Immediately with Daclatasvir Plus Asunaprevir Versus Delaying Treatment for HCV Patients in South Korea ·············································································································································································································· 167Do Young Kim, Byungyool Jun, Tae Hyun Kim, Sohee Park, Thomas Ward, Phil McEwan

PE-109 Cyclophilin Inhibitors Restore Attenuated Expression of MHC Class I Molecule in HCV-infected Cells ···························································· 168Seon-Hui Hong, Pil Soo Sung, In Soo Oh, Wonseok Kang, Su-Hyung Park, Eui-Cheol Shin

PE-110 Significance of Insulin Resistance in Chronic Hepatitis C Patients after Peg-interferon Based Therapy ···························································· 168Wang Yong Choi, Woo Jin Chung, Min Young Do, Jung Min Kim, Chang Jae Hur, Tae Hyung Kwon, Byoung Kuk Jang, Jae Seok Hwang

PE-111 Estimation of Direct Medical Cost related to the Management of Chronic Hepatitis C and Its Complications in Korea ·································· 168Do Young Kim, Ki Tae Yoon, Yong Han Paik, Won Kim, Jung Il Lee, Danbi Lee, Jung Won Jang, Jong Won Choi, Il Su Kim

PE-112 Elimination of Hepatitis C Virus (HCV) in South Korea ···································································································································· 169Do Young Kim, Young Suk Lim, Moon Seok Choi, Young Seok Kim, Sarah Blach, Homie Razavi, Kwang-Hyub Han

PE-113 Seroprevalence of Hepatitis C Infection and Risk Factor Assessment: A Hospital based Study ········································································ 169Dhruba Acharya, Bikash Bogati, Sarita Bhandari, Sashi Wenju

Liver Cancer, Basic

PE-114 Chromatin Remodeler SNF5 as Therapeutic Targets in Liver Cancer ··············································································································· 170Seong Hwi Hong, Sung Kyung Choi, Jueng Soo You

PE-115 In Vivo HCC-targeting Gene Therapy by Trans-splicing Ribozyme and Liver-specific Promoter Augumented by Rebuilded Adenoviral Construct and microRNA Regulation ······················································································································································································ 170Jin Sook Jeong, Mi-Ha Ju, Sang Young Han

PE-116 The Hepatitis B Virus X Protein Induces the Phenotype of Epithelial-mesenchymal Transition through Control CD44 in HCC Cell Lines ········ 170Na Ri Park, Jung Hoon Cha, Hye-Lim Kim, Won Hee Hur, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon

PE-117 The Roles of Kras Isoforms in Liver Cancer ······················································································································································ 171Hyuk Moon, Sook In Chung, Kyung Joo Cho, Hye-Lim Ju, Dayoung Kim, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Simon Weonsang Ro

PE-118 Inhibition of Discoidin Domain Receptor 2 May Enhance the Antitumor Effect of Sorafenib in a Hepatocellular Carcinoma Patient-Derived Xenograft (PDX) Model ···································································································································································································· 171Jin Sook Kim, Joong-Won Park, Sook-Kyung Lee, Bo Hyun Kim, Eun Kyung Hong

PE-119 Development of Hepatocellular Carcinomas in the Background of Liver Fibrosis Using a Transgenic Mouse Model ······································· 172Kyung Joo Cho, Sook In Chung, Hyuk Moon, Hye-Lim Ju, Dayoung Kim, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Simon Weonsang Ro

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PE-120 Differential Tumorigenic Effects by c-Myc Mutants in Liver Cancer ················································································································· 172Sook In Chung, Hye Lim Ju, Do Young Kim, Sang Hoon Ahn, Kwang-Hyub Han, Simon Weonsang Ro

PE-121 Demographic Profile and Treatment Outcomes of Filipino Patients with Hepatocellular Carcinoma in a Liver Tumor Registry ························ 172ARB Lomboy, JM Libuit, IMG Vicente, GC Firmalino, GCA Carpio, JP Ong

PE-122 Up-regulation of miR-128 in the Pathogenesis of Hepatocellular Carcinoma ·································································································· 173Chol Kyoon Cho, Eun Kyu Park, Hee Joon Kim, Young Hoe Hur, Yang Seok Koh

PE-123 Inhibition of Integrin Linked Kinase Augments Sorafenib Sensitivity of Hepatocellular Carcinoma Cells by Up-regulation of Anoikis ············· 173Eun Ju Cho, Su Jong Yu, Hyeki Cho, Hongkeun Ahn, Young Youn Cho, Minjong Lee, Jeong-Ju Yoo, Yuri Cho, Dong Hyeon Lee, Jeong-Hoon Lee, Yoon Jun Kim, Jung-Hwan Yoon

Liver Cancer, Clinical

PE-124 Comparison of the Clinical Features of Hepatocellular Carcinoma with Cryptogenic, Alcohol, and Viral Hepatitis Etiologies ························· 173Patricia Sun Te, Stephen Ng Wong

PE-125 Short-term Outcome of Laparoscopic Radiofrequency Ablation for Hepatocelluar Carcinoma in Liver Cirrhosis : The Safety and Efficacy ····· 174Byung Gon Na, Chan Woo Cho, Nuri Lee, Dong Kyu Oh, Wontae Cho, Jin yong Choi, Seung Hwan Lee, Sang Hoon Lee, Gyu Seong Choi, Jong Man Kim, Choon Hyuck Kwon, Jae-Won Joh, Jae Berm Park, Sung Joo Kim, Suk-Koo Lee

PE-126 Role of Enhancement Degree of Gd-EOB-DTPA-enhanced Magnetic Resonance Images for Prediction of Histologic Grade of Hepatocellular Carcinoma; Prospective Cohort Study ····························································································································································· 174Young-Joo Jin, Shin Il Kim, Seung Ho Lee, Soon Gu Cho, Joon Mee Kim, Jin-Woo Lee

PE-127 Prediction of Clinical Outcome after Radioembolization in HCC Patients: Role of 18F-FDG PET-CT ································································ 174Wonseok Kang, Mijin Yun, Jin-Young Choi, Jong Yun Won, Seung Up Kim, Kwang Hyub Han, Do Young Kim

PE-128 The Meaning of AFP, AFP-L3 and PIVKA-II for Evaluating Recurrence in Patients with Hepatocellular Carcinoma Who Underwent Liver Resection······················································································································································································································· 175

Sung Hoon Kim, Mee-Yon Cho, Moon Young Kim, Soon Koo Baik

PE-129 Evaluation of Fine Needle Aspiration Cytology of Malignant Mass Lesions of Liver ························································································· 175Ramesh Makaju

PE-130 Combination Treatment of Trans-arterial Chemoemobolization Followed by Radiotherapy with HyperThermia (CERT) in Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: Interim Analysis of Prospective Phase II Trial ·························································································· 175Jeong Il Yu, Hee Chul Park, Dongryul Oh, Jae Myoung Noh, Sang Hoon Jung, Hye Young Kim, Byung Chul Yoo, Geum-Youn Gwak, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Sung Wook Shin, Sung Ki Cho

PE-131 Combined Transarterial Chemoembolization and Radiotherapy for Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis: An External Validation Study of Clinical Significance ······································································································································· 176Jeong Il Yu, Jae Won Park, Hee Chul Park, Sang Min Yoon, Do Hoon Lim, Jong Hoon Kim

PE-132 Clinical Significance of Occult Hepatitis B Infection in Patients with Non-hepatitis B/Non-Hepatitis C-related Hepatocellular Carcinoma in a Hepatitis B Endemic Area ······························································································································································································· 176Bo Hyun Kim, Joong-Won Park, Sang-Hyun Hwang, Chang-Min Kim

PE-133 The Role of 18F-fluorodeoxyglucose (FDG)-Positron Emission Tomography (PET) for Accurate Staging and Optimal Treatment Planning in Patients with Hepatocellular Carcinoma ······································································································································································· 177Kyung Woo Park, Sang Gyune Kim, Young Seok Kim, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Hong Soo Kim, Boo Sung Kim, Jung Mi Park

PE-134 Glypican-3 Level Assessed by Enzyme-linked Immunosorbent Assay is Inferior to Alpha Fetoprotein For Hepatocellular Carcinoma Diagnosis······················································································································································································································· 177

Yejoo Jeon, Yun Suk Choi, Eun Sun Jang, Jin-Wook Kim, Sook-Hyang Jeong

PE-135 Radiation Therapy for Para-aortic Lymph Node Metastasis in Patients of Hepatocellular Carcinoma ······························································· 177Doo Yeul Lee, Tae Hyun Kim, Bo Hyun Kim, Joong-Won Park, Yeon-Joo Kim, Ju Hee Lee, Sang Myung Woo, Sung Ho Moon, Woo Jin Lee, Young Hwan Koh, Joo-Young Kim, Dae Yong Kim

PE-136 Risk Factors for Predicting Infectious Fever in Hepatocellular Carcinoma Patients with Fever after Transarterial Chemoembolization ············ 178Sun Seob Park, Joong-Won Park, Bo Hyun Kim, In Joon Lee, Ju Hee Lee, Young Hwan Koh, Hyun Boem Kim, Chang-Min Kim

PE-137 Antiviral Treatment after Curative Therapy of HBV-related HCC Improves the Outcome in Patients with High Serum HBV DNA Level ·········· 178Shim il Kim, Jin-Woo Lee, Young-Joo Jin, Jin-Seok Park, Young Soo Kim

PE-138 Comparative Analysis of Laparoscopic versus Open Surgical for Malignant Liver Tumors ··············································································· 178Kwangsik Chun, Seheon Kim, Yongwoo Yoon, Insang Song

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PE-139 Three-dimensional Conformal Radiotherapy for Portal Vein Tumor Thrombosis in Advanced Hepatocellular Carcinoma ······························· 179Hyun Young Woo, Jeong Heo, Kyung Lim Hwang, Won Lim, Ki Tae Yoon, Yong Mi Hong, Mong Cho, Won Taek Kim

PE-140 Oral Medications Improve the Compliance to Regular Surveillance for Hepatocellular Carcinoma in Chronic Hepatitis B Patients ·················· 179Joon Yeul Nam, Jeong-Hoon Lee, Dong Hyeon Lee, Young Chang, Hongkeun Ahn, Hyeki Cho, Jung-Ju Yoo, Minjong Lee, Young Youn Cho, Eun Ju Cho, Su Jong Yu, Yoon Jun Kim, Jung-Hwan Yoon

PE-141 Long-term Outcome after Resection of Huge Hepatocellular Carcinoma 10 cm: Single-institution Experience with 471 Patients ················ 179Shin Hwang, Young-Joo Lee, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Tae-Yong Ha, Gi-Won Song, Sung-Gyu Lee

PE-142 Model for Predicting Treatment Response of Sorafenib in Patients with Advanced Hepatocellular Carcinoma ··············································· 180Dong Hyeon Lee, Su Jong Yu, Yuri Cho, Jung-Ju Yoo, Minjong Lee, Young Youn Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Jung-Hwan Yoon

PE-143 Clinical Features and Treatment Modalities of Long-Term Survivors with Advanced Hepatocellular Carcinoma: A Single Institution Cohort Study······················································································································································································································· 180

Kyung Hee Kim, Bo Hyun Kim, Chang-Min Kim, Byung Ho Nam, Joong-Won Park

PE-144 High Dose and Compartmental Target Volume May Improve Outcome of Radiotherapy for Pelvic Bone Metastases from Hepatocellular Carcinoma······················································································································································································································· 181

Tae Hyung Kim, Hye Jung Cha, Jun Won Kim, Jinsil Seong, Ik Jae Lee

PE-145 Pseudocirrhosis as a Potential Mimic of Infiltrative Hepatocellular Carcinoma ································································································· 181Su Lim Lee, Yoo Dong Won, Hee Yeon Kim, Chang Wook Kim

PE-146 Development of Hepatocellular Carcinoma in Patients Outside Current Treatment Recommendation by KASL Guideline ······························ 181Jung Hee Kim, Dong Hyun Sinn, Ji Hyeon Lee, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Joon Hyeok Lee, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo

PE-147 Factors Predicting Hepatocellular Carcinoma Progression and Poor Prognosis after Transarterial Chemoembolization ··································· 182Sun Young Shin, Ga Won Song, Kyu-hyun Han, Suk Pyo Shin, Seong Gyu Hwang, Kyu Sung Rim, Hana Park

PE-148 Is Totally Laparoscopic Approach for Left Hepatectomy the Reliable Procedure Even in Cases with Severe Peri-Hepatic Adhesion? ··············· 182Hun Tak Ha, Young Seok Han, Jae Min Chun

PE-149 Percutaneous Ethanol Injection Therapy is Comparable to Radiofrequency Ablation in Early Stage Hepatocellular Carcinoma: Long-Term Outcomes and Prognostic Factors ···················································································································································································· 182Su Jong Yu, Jung-Hwan Yoon, Young Youn Cho, Jeong-Ju Yoo, Minjong Lee, Dong Hyeon Lee, Yuri Cho, Eun Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Chung Yong Kim

PE-150 Repeated Stereotactic Body Radiotherapy for Recurrent Hepatocellular Carcinoma ························································································ 183Won Il Jang, Mi-Sook Kim, Hyung Jun Yoo, Chul Koo Cho, Young Seok Seo, Chul Ju Han, Jin Kim, Su Cheol Park, Sang Bum Kim, Eung-Ho Cho

PE-151 Immunohistochemical Markers for Prognosis of Hepatocellucar Carcinoma after Liver Resection and Liver Transplantation ·························· 183Gun Hyung Na, Soo Ho Lee, Eun Young Kim, Tae Ho Hong, Young Kyoung You, Dong Goo Kim

PE-152 Treatment Outcome and Prognosis of Patients with Hepatocellular Carcinoma with Inferior Vena Cava and/or Cardiac Invasion ·················· 184Seawon Hwang, Si Hyun Bae, Hyun Yang, Hae Lim Lee, Jeong Won Jang, Jong Young Choi, Seung Kew Yoon

PE-153 Surgical Outcomes of Laparoscopic Right Hepatectomy Using the Combined Approach Compared with The Conventional Approach ········· 184Sung-Hwa Kang, Ki-Hun Kim

PE-154 Transarterial Chemoembolisation in Treatment of Liver Tumors in Accordance with Features of Their Angioarchitecture ······························ 184K. Ismembetov, T. Tuganbekov, S. Borovskiy, N. Malayew, N. Shanasarov, D. Tyo

PE-155 TACE in the Treatment of Hepatocellular Carcinoma in Kazakhstan (Southern Part) ······················································································ 185Ormanov N.K, K.R. Umarov, Isametov D.R., Abdurasulov R.R., Abdurakhmanov B.A, D.W. Tyo

PE-156 Effectiveness of Surveillance on Early Diagnosis of Hepatocellular Carcinoma ································································································ 185Seong Kyun Na, Chung-gi Park, Sung-eun Kim, Young-Suk Lim

PE-157 Prognostic Factors of Intrahepatic Cholangiocarcinoma Revisited ··················································································································· 186Wooil Kwon, Huisong Lee, Jin Young Park, Jin Seok Heo, Sung Ho Choi, Dong Wook Choi

PE-158 Living Donor Liver Transplantation after Combined Transarterial Chemoembolization and Radiotherapy for Hepatocellular Carcinoma with Major Vascular Invasion ····························································································································································································· 186Yuri Jeong, Sang Min Yoon, Min-Ho Shin, Gi-Won Song, Ki-Hun Kim, Chul-Soo Ahn, Deok-Bog Moon, Shin Hwang, Jong Hoon Kim, Sung-Gyu Lee

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Liver Transplantation

PE-159 Technical Knacks to Enhance Luminal Patency of Interposed Synthetic Graft in Living Donor Liver Transplantation Using Modified Right Liver Graft······················································································································································································································· 187

Seok-Hwan Kim, Shin Hwang, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Chul-Soo Ahn, Deok-Bog Moon, Ki-Hun Kim, Gil-Chun Park, Bo-Hyun Jung, Sung-Hwa Kwang, Young-In Yoon, Min-Ho Shin, Wan-Jun Kim, Kang Woo-Hyoung, Sung-Gyu Lee

PE-160 Comparison of Technical Handling and Luminal Patency between Interposed PTFE Grafts with Interrupted Rings versus Continuous Spiral Rings in Living Donor Liver Transplantation Using Modified Right Lobe Graft ·············································································································· 187Seok-Hwan Kim, Shin Hwang, Tae-Yong Ha, Gi-Won Song, Dong-Hwan Jung, Chul-Soo Ahn, Deok-Bog Moon, Ki-Hun Kim, Gil-Chun Park, Bo-Hyun Jung, Sung-Hwa Kwang, Young-In Yoon, Min-Ho Shin, Wan-Jun Kim, Woo-Hyoung Kang, Sung-Gyu Lee

PE-161 Hepatitis B Virus-related Mixed Hepatocellular-Cholangiocarcinoma in Patients Undergoing Liver Transplantation ········································ 187Juhan Lee, Seung Hwan Song, Jae Geun Lee, Dae Hoon Han, Man Ki Ju, Jin Sub Choi, Myoung Soo Kim, Dong Jin Joo

PE-162 The Start of Liver Transplantation at the Public Hospital in Korea ··················································································································· 188Doo-ho Lee, Hae Won Lee, Young Joon Ahn, Hyeyoung Kim, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh

PE-163 A Case of Early Organizing Portal Vein Thrombosis Followed by Arterio-Portal Shunt without Hepatic Dysfunction after Liver Transplantation······················································································································································································································· 188

Tae-Seok Kim, Koo Jeong Kang, Keun Soo Anh, Yong Hoon Kim, Hyoung Tae Kim

PE-164 Effectiveness of Continuous Wound Infusion of Ropivacaine for Postoperative Pain Management after Donor Hepatectomy in Living Donor Liver Transplantation ······························································································································································································· 189Suk-Won Suh, Yoo-Shin Choi, Hyeyoung Kim, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh

PE-165 Renal Function Difference between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined with Entecavir ··················· 189Jae Geun Lee, Juhan Lee, Jung Jun Lee, Myoung Soo Kim, Man Ki Ju, Gi Hong Choi, Jin Sub Choi, Soon Il Kim, Dong Jin Joo

PE-166 Biliary Complication after Living Donor Liver Transplantation According to Biliary Reconstruction Methods ··················································· 189Jae Geun Lee, Juhan Lee, Seung Hwan Song, Jung Jun Lee, Man Ki Ju, Myoung Soo Kim, Dong jin Joo

PE-167 Post-transplant Lymphoprolieferative Diseases in Pediatric Liver Recipients ····································································································· 190Jae Geun Lee, Juhan Lee, Seung Hwan Song, Jung Jun Lee, Myoung Soo Kim, Man Ki Ju, Dong Jin Joo

PE-168 Donor Safety and Recipient Liver Function Following Right- lobe Liver Transplantation from Donor with Gilbert Syndrome ·························· 190Woo-Hyoung Kang, Shin Hwang, Gi-Won Song, Dong-Hwan Jung, Tae-Yong Ha, Gil-Chun Park, Chul-Soo Ahn, Deok-Bog Moon, Ki-Hun Kim, Bo-Hyun Jung, Sung-Hwa Kwang, Young-In Yoon, Min-Ho Shin, Wan-Jun Kim, Seok-Hwan Kim, Sung-Gyu Lee

PE-169 Single-center Experience of ABO Incompatible Living Donor Liver Transplantation with New Simplified Intravenous Immunoglobulin Protocol: A Propensity Score Matching Analysis ····························································································································································· 191Joo Dong Kim, Dong Lak Choi

PE-170 Transplant Program Development in Kazakhstan: Experience of 11 Years ······································································································ 191Yermakhan Assylkhanuly, Gani Kuttymuratov, Tokan Sultanaliev, Adilbek Mukazhanov, Asan Zhexembaev, Kakharman Yesmembetov, Zhanar Abisheva, Mels Assykbaev, Aiymkul Ashimkhanova, Saitkarim Abdugafarov, Zhaksylyk Doskaliev, Marlen Doskali

PE-171 Experience from the First Liver Transplant Program in Kazakhstan ·················································································································· 192Saifkarim Abdugofarov, Gani Kuttymuratov, Tokan Sultnaliyev, Zhaksylyk Doskaliev, Marlen Doskali, Kakharman Yesmembetov, Yermakhan Assylkhanuly, Aiymkul Ashimkhanova, Mels Asykbayev

PE-172 Tuberculosis after Living Donor Liver Transplantation ····································································································································· 192Mels Assykbayev, Gani Kuttymuratov, Tokan Sultanaliev, Adilbek Mukazhanov, Asan Zhexembaev, Kakharman Yesmembetov, Aiymkul Ashimkhanova, Saitkarim Abdugafarov, Yermakhan Assylkhanuly, Dulat Serikbaiuly, Yerzhan Sakhishev

PE-173 Rapid Progression of Alcoholic Steato-hepatitis after Liver Transplantation : A Case Report ··········································································· 193Seung Hwan Song, Juhan Lee, Jae Geun Lee, Myoung Soo Kim, Dai Hoon Han, Gi Hong Choi, Jin Sub Choi, Soon Il Kim, Dong Jin Joo

Surgery

PE-174 The Role of International Collaborative Program in Development of Adult-to-adult Living-donor Liver Transplantation Program in National Scientific Medical Research Center ················································································································································································· 193Doskali M, Lee KW, Saparbay J, Choi YR, Suh SW, Kuttymuratov G, Rysmakhanov M, Kushenova S, Taganova A, Kulmaganbetov A, Smagulov A, Seidakhmetov A, Baigenzhin A, Doskaliyev Zh

PE-175 Successful Treatment of Hydatid Cysts Caused by Echinococcus Multilocularis Using High-intensity Focused Ultrasound: 3-Year Follow up Management ·································································································································································································· 194Kulmaganbetov A, Doskali M, Imankulov S, Baigenzhin A, Doskaliyev Zh

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PE-176 Single Center Experience of Management of Large Hepatic Hemangiomas ···································································································· 194Taganova A, Doskali M, Rysmakhanov M, Tashev I, Doskaliyev Zh, Baigenzhin A

PE-177 Management of Hepatic Multivesicular and Complicated Hydatid Cysts: Surgical Options and Postoperative Care ········································ 194Smagulov A., Doskali M., Rysmakhanov M, Taganova A., Kulmaganbetov A., Seidakhmtov A., Tashev I., Doskaliyev Zh.

PE-178 Regional Development of Living Donor Kidney Transplantation in Kazakhstan. Results and Prospects ··························································· 194Kaliev A., Zhakiyev B., Sultangereev E., Mussin N.

PE-179 Sofosbuvir + Peg-Interferon + Ribavarin Therapy Result for A Patient with Hepatitis C Virus Related Liver Cirrhosis and Hypersplenism ········ 195Ts. Enkh-Amgalan, N. Batsaikhan, A. Bold, E. Gerelmaa, B. Dulguun, G. Sarantuya

PE-180 A Case of Bile Duct Adenoma Developed in Hepatic Hilar Portion Mimicking Klatskin’s Tumor ······································································ 195Young Hoe Hur, Chol Kyoon Cho

PE-181 Combined Targeting of mTORC1 and mTORC2 Synergistically Inhibits Proliferation of Hepatocellular Carcinoma Cells: Effects of Everolimus and Ku0063794 ····································································································································································································· 196Say-June Kim, Jae Woo Park, Sang Kuon Lee

PE-182 Lipopolysaccharide Preconditioning of Adipose-derived Stem Cells Improves Liver-regenerating Activity of The Secretome ··························· 196Say-June Kim, Jae Woo Park, Sang Kuon Lee

PE-183 The Liver Graft Adaptation to the Early Hepatic Artery Occlusion after Living Donor Liver Transplantation Case Report ································ 197Koba Shanava, Young Rok Choi, Nikoloz Ubiria, Khakha Quntelia, Tina Khutsishvili, Merab Janelidze, Soso Gelashvili, Giorgi Giorgobiani, Kwang Woong Lee

PE-184 Results of Splenic Artery Embolization Following Adult-to- adult Living Donor Liver Transplantation ····························································· 197Rysmakhanov M, Doskali M, Baygenzhin A, Doskaliyev Zh

PE-185 Lymph Node Ratio vs. Total Number of Lymph Node Metastasis for Prediction of Oncologic Outcome in Pancreatic Head Cancer ··············· 197Jar Uk Chong, Chang Moo Kang

PE-186 Defining Practical N-staging System to Predict Oncologic Outcome in Resected Left Sided Pancreatic Cancer ··············································· 198Sung Hyun Kim, Chang Moo Kang

PE-187 The Significance of Lymph Node in Pancreatic Neuroendocrine Tumors: Is Dissection Absolutely Necessary? ················································· 199Wooil Kwon, Jin-Young Park, Kee Taek Jang, Jin-Seok Heo, Seong-Ho Choi, Dong Wook Choi

PE-188 X-Ray Endovascular Intervention in Portal Hypertension ·································································································································· 199S.P. Borovskiy, A.K. Mukazhanov, A.A. Zheksembayev, Zh.K. Aysin, B.E. Ibrayev, A.K. Nurmagambetova

PE-189 Real-Life Effectiveness of Different Antiviral Therapy Regimens in Treatment of HDV-Infection ······································································ 200K.I. Yesmembetov, D.T. Abdurakhmanov, N.A. Mukhin

PE-190 The Results of Transarterial Chemoembolization for Malignant Liver Tumors ································································································· 200S.P. Borovsky, N.A. Shanazarov, . . Mukazhanov, . . Zheksembayev, . . Kerimkulov

PE-191 Surgical Approach Did Not Impact on Oncology Outcome in Middle Bile Duct Cancer; Bile Duct Segmental Resection vs. Pancreaticoduodenectomy······················································································································································································································· 200

Jiae Park, Chang Moo Kang

PE-192 Feasibility of Enhanced Recovery after Surgery Pathway in Pancreaticoduodenectomy for Non-surgical Complication Patients ····················· 201Jin Young Park, Seong Ho Choi, Wooil Kwon, Jin Seok Heo, Dong Wook Choi

PE-193 Laparoscopic Enucleation of Pancreatic Benign Neoplasm; Single Center Experience ····················································································· 201Jin Young Park, Seong Ho Choi, Wooil Kwon, Jin Seok Heo, Dong Wook Choi

PE-194 Clinical Feautures of Curatively Resected Neuroendocrine Carcinoma of the Gallbladder ··············································································· 202Jin Young Park, Dong Wook Choi, Wooil Kwon, Jin Seok Heo, Seong Ho Choi

PE-195 Aggressive Radical Resection for Type IIIb Compared to Type IIIa Hilar Cholangiocarcinoma ·········································································· 202Jin Young Park, Dong Wook Choi, Wooil Kwon, Jin Seok Heo, Seong Ho Choi

PE-196 Hepatic Allograft Salvage in LDLT after Early HAT by Combined Surgical and Angiographic Techniques ························································ 202B.B. Baimakhanov, A.T. Chormanov, M.M. Sakhypov, B.S. Ilyasova, T.K. Kuandykov, B.B. Mutagirov, N.N. Birzhanbekov, A.A. Astai, E. Serikuly, Ch.T. Sadykov, D.Z. Bayguisova, F.T. Stamkulov

PE-197 Experience of Related Liver Transplantation ···················································································································································· 202S.A. Abdualiyev

PE-198 Reconstructive Surgery for Bile Duct Strictures ················································································································································ 203G.S. Abezhanova

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PE-199 Biliary Cast Syndrome in a Patient after Endoscopic Retrograde Cholangiopancreatogram and Cholecystectomy ·········································· 203Jaime Yap Haw Jr, Arsenio Lim Co

Others

PE-200 Enhanced Direct Conversion of Fibroblasts into Hepatocyte- like Cells via Accelerated Reprogramming Kinetics ··········································· 203Kyung Tae Lim, Seung Chan Lee, Jonghun Kim, Dong Wook Han

PE-201 Primary Paraganglioma of Liver: A Rare Tumor at an Unusual Location ·········································································································· 204Jeong Eun Song, Sang Ah Baek, Byeong Suk Kim, Chang Hyeong Lee

PE-202 Obscure Overt Gastrointestinal Bleeding from Jejunal Varices: a Case Report ································································································· 204Mara Teresa T. Panlilio, Jeffrey M. Libuit, Allyn Rey D. Lomboy, Janus P. Ong

PE-203 A Case of Alcoholic Liver Cirrhosis First Presenting with Dyspnea due to Portopulmonary Hypertension ························································ 205Hyung Gyu Choi, Chang Wook Kim, Hee Yeon Kim, Ji Young Kim, Yoo Dong Won, Su Lim Lee

PE-204 A Case of Primary Gastrointestinal Stromal Tumor of the Liver ······················································································································· 205Hyung Gyu Choi, Chang Wook Kim, Hee Yeon Kim, Ji Young Kim, Yoo Dong Won, Su Lim Lee

PE-205 Complication of Amebic Liver Abscess: Biliary Fistula ······································································································································ 205Han Wook Chung, In Soo Oh, Hyun Woong Lee, Hyung Joon Kim

PE-206 The Necessity of Computed Tomography to Hepatic Lesions Detected on Private Clinic Sonography ····························································· 206Suk Bae Kim, Sung Hwan Han, Ki Bae Bang, Joon Ho Choi, Seung Min Jeon, Deok Hyun Shin, Jung Eun Shin, Hong Ja Kim, Il Han Song

PE-207 Predictors of Early Regeneration in Remnant Liver Volume after Hepatectomy ······························································································· 206Jae Do Yang, Woo Sung Moon, Baik Hwan Cho, Hee Chul Yu

PE-208 Association of Erectile Dysfunction with Depression in Patients with Chronic Viral Hepatitis ·········································································· 206Bong Oh Ma, Hae Jin Yang, Sang Goon Shim

PE-209 A Case of Acute Q Fever and Hepatitis Followed by High Long-term Titers Indicative of an Undetermined Stage ·········································· 207Oscar Vargas Montealegre, Hee Bok Chae

PE-210 Laparoscopic Excision versus Unroofing for a Giant Hepatic Cyst ···················································································································· 207Kee-Hwan Kim , Soo-Ho Lee, Chang-Hyeok An, Jeong-Soo Kim

PE-211 Biomarker stratified, Prospective Clinical Trial to Assess the Efficacy of Hepatic Arterial Infusion of Cisplatin and 5-fluorouracil in HCC ········ 207Jung-Hee Kwon, Moo-Sang Kim, Jin Young Park, Yun Suk Yu, Si Hyun Bae, Hee Jung Wang

SYMPOSIUM 1 Consensus Meeting on the Noninvasive Diagnosis of Cirrhosis

Noninvasive Tools for the Diagnosis of Cirrhosis: Is TE Not Enough by Itself? ··············································································································· 211Laurent Castera

Optimal Cutoff Value of Transient Elastography for the Diagnosis of Cirrhosis ············································································································· 212Do Young Kim

Non-invasive Evaluation of Liver Fibrosis in China ························································································································································· 213Jun Cheng, Jingxin Zhao, Huichun Xing

Special Lecture 1

Acute on Chronic Liver Failure ······················································································································································································ 217Richard Moreau

SYMPOSIUM 2 Liver-Gut Axis

Microbiome and the Liver - Clinical Implications ··························································································································································· 221Robert Schwabe

Cutting-edge Methods of Human Microbiota Research Using Korean Twins ················································································································ 222GwangPyo Ko

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Can We Modulate Microbiome? ··················································································································································································· 223Yoon-Keun Kim

Liver-Gut Axis: Fibrosis and HCC ··················································································································································································· 224Yong-Han Paik

VIRAL HEPATITIS FORUM I HCV: From Discovery to Eradication

HCV: Virus Life Cycle and Targets of DAA ···································································································································································· 229Seungtaek Kim

History of Drugs: From Interferon to DAA ····································································································································································· 230Lai Wei

Treatment Options: West vs. East ················································································································································································· 231W. Ray Kim

Hepatitis C virus Coopts Host Ankyrin Repeat Domain 1 for Its Own Propagation ········································································································ 233Soon Bong Hwang

VIRAL HEPATITIS FORUM II HBV: From Discovery to Eradication

The Virus and Pathogenesis ··························································································································································································· 237Yasuhito Tanaka

Treatment: Two Decades of Progress ············································································································································································ 238Jia-Horng Kao

Revisit Quantitative HBsAg and cccDNA ········································································································································································ 239Man-Fung Yuen

New Trials Toward a Cure ····························································································································································································· 240Sang Hoon Ahn

ASIA-PACIFIC JOINT SYMPOSIUM I HBV: Immuno-and Bio-therapeutic Approach to Cure Chronic Hepatitis B Virus Infection

Immunopathogenesis of HBV Infection and Principle of Immunotherapy for HBV Infection ·························································································· 243Antonio Bertoletti

Clinical Experience of HBV DNA Vaccine in Korean Patients with Chronic HBV Infection ······························································································ 244Seung Kew Yoon

Optimized Immunotherapy to Cure Chronic HBV Infection by Using a Convenient Immuno-competent Mouse Model ··············································· 251Pei-Jer Chen

ASIA-PACIFIC JOINT SYMPOSIUM II Management of Chronic Hepatitis C: Clinical Issues and Future Perspective

Hepatitis C: National-wide Screening of HCV ································································································································································ 255Lai Wei

Hepatitis C: Interferon-based Regimens, Still Useful or Useless? ··································································································································· 256Young Seok Kim

Future Use of DAAs in Asia-Pacific Region ···································································································································································· 257Ming-Lung Yu

ASIA-PACIFIC JOINT SYMPOSIUM III Management of Chronic Hepatitis B: Clinical Issues and Future Perspective

Management of Chronic Hepatitis B: Nation-wide Cohort Studies ······························································································································· 261Chun-Jen Liu

Management of HBV Antiviral Resistance ····································································································································································· 262Young-Suk Lim

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HBV Treatment Initiation and Cessation Criteria ··························································································································································· 264Di Wu, Qin Ning

Beyond the Antiviral Therapy to Reduce the Risk of Liver Cancers in Chronic Hepatitis B ····························································································· 265Shiou-Hwei Yeh

CLINICAL HEPATOLOGY UPDATE ASH and NASH

Mechanism-based New Target for Therapy in ASH ······················································································································································· 269Won Kim

To Drink or Not To Drink? That is the Question ···························································································································································· 270Seung Ha Park

Management of Alcohol Dependence in Clinic ····························································································································································· 271Suk Bae Kim

Drug Therapy for NAFLD: What is New? ······································································································································································· 280Yun Soo Kim

SYMPOSIUM 3 Debates in the Treatment of Portal Hypertension

Antibiotic Prophylaxis: Which Drug, For Whom, For How Long? ·································································································································· 287Won Hyeok Choe

Coagulopathy: Is It a Complication or a Treatment Target? ·········································································································································· 292Samuel Lee

Minimal Hepatic Encephalopathy: Should Be Treated or Not? ······································································································································ 293B. C. Sharma

Radiological Intervention: When Should It Be Considered in Patients with Complications of Portal Hypertension? ······················································ 294Sung Ki Cho

SPECIAL LECTURES 2 Emerging Trends in Treatments of Chronic Liver Disease

New Paradigms for Hepatitis C ····················································································································································································· 297W. Ray Kim

The Evolution of HCC Treatment ·················································································································································································· 299Masatoshi Kudo

Fifty Years of Japanese Hepatology: Past, Present and Future ······································································································································· 300Kazuhiko Koike

STATE-OF-THE-ART LECTURE

Non-invasive Tools for the Diagnosis and Management of Cirrhosis ····························································································································· 303Laurent Castera

KASL & KSSCR JOINT SYMPOSIUM Liver Regeneration: Where We Are

Basic Techniques: Hepatocytes and Matrix (Bioartificial Liver) ······································································································································· 307Suk-Koo Lee

Feasibility of Placenta-derived Stem Cells on Hepatic Failure Models ···························································································································· 308Gi Jin Kim

Adult Stem Cells: Basic to Clinical (Basic, Mesenchymal Stem Cells to Hepatocytes) ····································································································· 309Ja Kyung Kim

Direct Lineage Transition by Defined Factors ································································································································································· 314Dong Wook Han

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KLTS COORDINATOR PROGRAM The Role of Coordinator in Liver Transplant Field

Registration and Management of the Patients on Waiting List ····································································································································· 317Kyoung Ock Jeon

Pre-transplant Education and Counseling for the Liver Recipients ································································································································· 319Hea Seon Ha

Post-transplant Education and Counseling for the Liver Recipients ······························································································································· 323Ji Eun Lee

KLTS SYMPOSIUM HCC Recurrence after Liver Transplantation

Selection and Down-staging of Advanced HCC for Liver Transplantation ····················································································································· 327Francis Yao

Preventive Treatment for HCC Recurrence after Liver Transplantation: Role of mTOR Inhibitor and Adjuvant Treatment ············································· 331Kwang-Woong Lee

How to Diagnose and Manage HCC Recurrence after Liver Transplantation ················································································································· 333Gi-Won Song

KHBPS & KLTS JOINT SYMPOSIUM Care for Long-term Survivor after Liver Transplantation

Post-liver Transplantation Metabolic Syndrome ····························································································································································· 337Jaeseok Yang

Surveillance of Recurrence and De Novo Solid Tumors - De Novo Malignancies after Liver Transplantation: Incidence, Diagnosis and Treatment ······· 338Shin Hwang

Histopathology of Allograft Dysfunction in Late Period of Liver Transplantation ··········································································································· 339Kyoung-Bun Lee

Allograft Dysfuction: Mechanism and Prevention ·························································································································································· 342Hiroto Egawa

KHBPS & JSHBPS JOINT SYMPOSIUM 1 Recent Change in the Concept and Treatment in Cholangiocarcinoma

Changing Patterns of Incidence and Treatment Strategy for Cholangiocarcinoma ······································································································· 345Sang-Jae Park

Relationship between Recurrence Pattern of Intrahepatic Cholangiocarcinoma after Hepatic Resection and Hepatitis Virus (Multi-institutional Research) -Is Lymph Node Dissection Necessary? ··············································································································································································· 346Masaki Kaibori, Hiroya Iida, Hiroaki Nagano, Michihiro Hayashi, Takuya Nakai, Shigekazu Takemura, Hiroshi Wada, Fumitoshi Hirokawa, Yasuyuki Nakata, Shoji Kubo

Update in Non-surgical Treatment in Cholangiocarcinoma ··········································································································································· 347Hye Jin Choi

KHBPS & JSHBPS JOINT SYMPOSIUM 2 (Video Session) Lessons Learned from the Experts: How I Do Major Hepatic Resection?

Major Hepatic Resection for Hepatobiliary Cancer with Portal Venous Involvement ····································································································· 351Norihiro Kokudo, Yoshihiro Sakamoto, Kiyoshi Hasegawa

Anti-Situm In-situ Hypothermic Perfusion Hepatectomy for Liver CA on HV Confluence ······························································································ 352Sung-Gyu Lee

Surgical Challenge Beyond the Current Limit for Advanced Hepatocellular Carcinoma (HCC) with Extensive Portal Vein Tumor Thrombosis (PVTT) ··· 353Yonson Ku, Motofumi Tanaka, Takumi Fukumoto

KHBPS & JSHBPS JOINT SYMPOSIUM 3 (Video Session) Lessons Learned from the Experts: How I Do Donor Hepatectomy?

Various Types of Donor Resection, Left Side ································································································································································· 357Kyung-Suk Suh

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Various Types of Donor Resection - Right Side Liver Graft ············································································································································ 358Hee Jung Wang

Various Types of Donor Resection in Japan via Midline Incision ···································································································································· 359Toru Ikegami, Ken Shirabe, Tomoharu Yoshizumi, Yuji Soejima, Hideaki Uchiyama, Yo-ichi Yamashita, Yoshihiko Maehara

KLCSG & KHBPS JOINT SYMPOSIUM

Optimal Selection of Surgical Candidate in Non-conventional Setting ·························································································································· 363Dong-Sik Kim

Antiviral Therapy for the Prevention of HCC Recurrence after Surgical Resection ········································································································· 364Jung Il Lee

Surgery for HCC Patients with Portal Vein or Bile Duct Invasion ··································································································································· 367Choon Hyuck David Kwon

Surgical Resection versus Transcatheter Arterial Chemoembolization Followed by Radiation Therapy for the Treatment of Hepatocellular Carcinoma with Segmental/Subsegmental Portal Vein Tumor Thrombus ················································································································································ 368Hee Chul Park

KLCSG & LCSGJ JOINT SYMPOSIUM

HCC Nationwide Surveillance and Outcome in Korea ··················································································································································· 371Young-Suk Lim

HCC Nationwide Surveillance and Outcome in Japan ··················································································································································· 372Masatoshi Kudo

Indication of Surgical Resection and Pre-operative Evaluation for HCC in Korea ··········································································································· 373Nam-Joon Yi

Indication of Surgical Resection and Pre-operative Evaluation for HCC in Japan ··········································································································· 376Norihiro Kokudo, Jun-ichi Arita

Advance in Transarterial Treatment: Conventional TACE ·············································································································································· 377Shiro Miyayama

Advances in Transarterial Treatment: Drug-eluting Bead TACE ····································································································································· 378Jin Wook Chung

EVIDENCE BASED MANAGEMENT OF HCC

Bridging Pathologic Information into Clinics: The Role of Liver Biopsy in the Management of Hepatocellular Carcinoma ············································ 385Haeryoung Kim

Surgery versus Locoregional Therapy for Early HCC ······················································································································································ 387Su Jong Yu

Multimodal Treatments for Intermediate and Advanced Hepatocellular Carcinomas: Focused on the Non-Standard Options ······································ 392Jihyun An

Radiation Therapy in HCC: lmplications from Korean Multicenter Registry Study ········································································································· 394Jinsil Seong

AUTHOR INDEX ············································································································································································································· 399