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1 Unrestricted © Siemens Healthineers, 2021 Unrestricted © Siemens Healthineers, 2021 The future is in motion

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Basic versionThe future is in motion
Siemens Healthineers Imaging Power for RT
SOMATOM Confidence RT Pro 20/64 < 80cm >
with DirectDensity
with DirectDensity
Magnetom Vida / Sola RT Pro Edition
syngo.via RT image Suite
SOMATOM X.Cite 128 < 82cm >
with DirectDensity with DirectDensity
Click to add footnote second line
The future is in motion 640.35 0.6mm
2020110 go Sim/go Open Pro 302ADBZX00008000
85cm 85cmFOV
⇒±1mm@140cm
SOMATOM go.sim “ Accuracy of Table “
AAPM TG66 ±1°

0.03° 0.0° 0.5°
0.01° 0.0° 0.2°

Report of the AAPM Radiation Therapy Committee Task Group No.66
Siemens Healthineers
Alignment of gantry lasers with the center of imaging plane
±2mm ±1mm CT
Orientation of gantry lasers with respect to the imaging plane ±2mm ±2mm
- /
Orientation of the CT-scanner tabletop with respect to the imaging plane
±2mm ±1mm CT
Click to add footnote second line
SOMATOM go.sim
SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
64 0.35 0.6mm
SOMATOM go.Open Pro Scanning Speed:87.8mm/sec (0.6mm×640.8 0.35 350mm=4
8 Unrestricted © Siemens Healthineers, 2021
Push the boundaries with shorter scan times for deep inspiration breath-hold By combining a 4-cm detector with fast rotation times (0.35 s1), SOMATOM go.Open Pro covers more of the patient's anatomy in less time. An entire thorax scan takes just eight seconds.
1) Optional. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
Confident breast contouring thanks to high image quality
1. Technical specifications
2. Fast spiral scan with breath-hold
10 s for a whole thorax scan
Risk of a cardiovascular disease increases by 7.4% per 1 Gy mean heart dose1
TargetOAR = AI
9 Unrestricted © Siemens Healthineers, 2021
Push the boundaries with shorter scan times for deep inspiration breath-hold By combining a 4-cm detector with fast rotation times (0.35 s1), SOMATOM go.Open Pro covers more of the patient's anatomy in less time. An entire thorax scan takes just eight seconds.
1) Optional. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
Confident breast contouring thanks to high image quality
1. Technical specifications
2. Fast spiral scan with breath-hold
10 s for a whole thorax scan
Risk of a cardiovascular disease increases by 7.4% per 1 Gy mean heart dose1
TargetOAR = AI
2020-02-17Page 10 Unrestricted © Siemens Healthineers, 2021
iMAR
Thanks to the Adaptive Sinogram Mixing, iMAR applies different metal artifacts reduction methods accordingly to the severity of the artifacts
2020-02-17Page 11 Unrestricted © Siemens Healthineers, 2021
Unrestricted © Siemens AG 2015 All rights reserved.
Page 11 January 2015 Alexandre Ripert / HC IM CR RO
Courtesy of Rigshospitalet, Copenhagen, Denmark
with iMARwithout iMAR
2020-02-17Page 12 Radiation Oncology
iMAR + HD FOV Breast cancer case with shoulder implants
SOMATOM Confidence
Reduction of artifacts thanks to iMAR and HD FoV Pro in the case of a obese patient.
collimation: 16 x 1,2 mm scan time: 37 s scan length: 725 mm rotation time: 0.5 s 140 kV, 500 mAs CTDIvol: 46.88 mGy DLP: 3357.1 mGycm
Courstesy of Rigshospitalet, Copenhagen, Danmark
2020-02-17Page 13 Unrestricted © Siemens Healthineers, 2021
Unrestricted © Siemens AG 2015 All rights reserved.
Page 13 2020-02-17 Alexandre Ripert / HC IM CR RO
Courtesy of Rigshospitalet, Copenhagen, Denmark
with iMARwithout iMAR
2020-02-17Page 14 Radiation Oncology
. Unrestricted © Siemens AG 2015
Great HU accuracy ideal for dose calculation
Potential dose discrepancy by as much as 4% if the WFBP images are used
Potential dose discrepancy by as much as 5% if the WFBP images are used
Courtesy of DKFZ, Germany *optional
iMAR
Varian RGSC Prospective Conventional Scan ( Step & Shoot )
Varian RGSC integrated Flexible Respiratory & Gating
2020-02-17Page 16 Unrestricted © Siemens Healthineers, 2021
Varian RGSC Retrospective Spiral scan ⇒ 4DCT
Varian RGSC integrated Flexible Respiratory & Gating
2020-02-17Page 17 Unrestricted © Siemens Healthineers, 2021
Spiral Scan (4D)
Slow Pitch scan with Respiratory & Gating ( Lowest Pitch = 0.05 ) 300
Unrestricted © Siemens Healthineers, 2021
Page 19 Unrestricted © Siemens Healthineers, 2021
4D Imaging with Retrospective Respiratory & Gating

4CTStep&Shoot (CINE) Definition AS 4D(0.09)
2020-02-17Page 20 Unrestricted © Siemens Healthineers, 2021

0%
50%
0%
50%
100%
t-Space View Long Scan
0%
50%
100%
0%
50%
100%
0%
50%
100%
0%
50%
100%
Direct i4D1
World’s first 4D CT sequence that adapts to the patient’s breathing in real time
only for SOMATOM go.Open Pro
Push the boundaries with intelligent Direct i4D1
Potential for smaller target margins
1) Optional, online gating device such as RGSC or Anzai is required. Direct i4D is pending 510(k) clearance, and is not yet commercially available in the United States. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
23 Unrestricted © Siemens Healthineers, 2021
Push the boundaries with intelligent Direct i4D1
Potential for smaller target margins
Direct i4D is an AI-powered 4D CT sequence that intelligently adapts to the patient’s breathing in real time. The AI algorithm monitors the breathing pattern throughout acquisition and reconstruction.
1) Optional, online gating device such as RGSC or Anzai is required Direct i4D is pending 510(k) clearance, and is not yet commercially available in the United States. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
Adapting to the patient's breathing potentially reduces image artifacts for smaller target margins
1. Direct i4D adapts scan protocol to patient’s breathing pattern
Breathing
Time
2. Direct i4D chooses optimal data for 4D CT reconstruction
3. Automated 4D reconstruction incl. multi-series splitting
TPS
Push the boundaries with intelligent Direct i4D1
Potential for smaller target margins
Direct i4D is an AI-powered 4D CT sequence that intelligently adapts to the patient’s breathing in real time. The AI algorithm monitors the breathing pattern throughout acquisition and reconstruction.
1) Optional, online gating device such as RGSC or Anzai is required Direct i4D is pending 510(k) clearance, and is not yet commercially available in the United States. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
Breathing
Time
*Aborted

“ 1
‘ “
25 Unrestricted © Siemens Healthineers, 2021
25
Potential for smaller target margins
85% reduction in image artifacts1
Compared to a standard 4D CT protocol; based on a preliminary study with 189 patients2
1) Optional. 2) Werner R et al. Intelligent 4D CT Sequence Scanning (i4DCT). Best of ASTRO 2018. Direct i4D is pending 510(k) clearance, and is not yet commercially available in the United States. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
Unrestricted © Siemens Healthineers, 2021
Push the boundaries for lung imaging
Push the boundaries with intelligent Direct i4D1
Potential for smaller target margins
Your benefits:
• Robust and simple 4D image acquisition for every user, with potential to avoid time- consuming edits
• Fewer motion artifacts for exceptionally accurate visualizations of moving tumors
• Clear visualization for smaller target margins
1) Optional. Image courtesy of MAASTRO clinic, Maastricht, The Netherlands (SOMATOM Confidence® RT Pro). Direct i4D is pending 510(k) clearance, and is not yet commercially available in the United States. SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
Without Direct i4D With Direct i4D (simulation)
Direct i4D can potentially reduce target margins
Unrestricted © Siemens Healthineers, 2021Unrestricted © Siemens

CARE kV
29 Unrestricted © Siemens Healthineers, 2021
TwinSpiral Dual Energy is a new form of dual-energy acquisition that uses Tin Filter to achieve optimal spectral separation. By reducing scan times, it is especially suitable for cases involving motion.
Push the boundaries with TwinSpiral Dual Energy1
Improved spectral separation
Precise target delineation thanks to improved soft- tissue contrast
Better spectral separation with Tin Filter 7 s (80 kV) + 3 s (delay) + 7 s (140 kV) acquisition2
Number of quanta
SOMATOM go.sim 80 kV Sn140 kV Overlap
1) Optional. 2) Default DE Monoenergetic Plus protocol (pitch = 0.8, rotation time = 0.5 s, collimation = 64x0.6 mm). SOMATOM go.Open Pro is pending 510(k) clearance, and is not yet commercially available in the United States.
80 kV
140 kV
Dual Energy Monoenergetic Plus Malignant neoplasm of sinus maxillaris
120 kV ( single energy) 40 keV (Dual Energy)
Tumor
Standard energy level
40 keV Mono +
kV : 80 / 140 Collimation: 32 x 0.6 mm Scan time : 5.2 s x 2 Rotation time: 0.35 s
Necrosis
Unrestricted © Siemens Healthineers, 2021
Hanno Dotzel |Guillaume Grousset
Necrosis
Tumor
Standard energy level
40 keV Mono +
SOMATOM Confidence® RT Pro kV : 80 / 140 Collimation: 64 x 0.6 mm Scan time : 3.2 s x 2 Rotation time: 0.5 s
Necrosis
Necrosis
Unrestricted © Siemens Healthineers, 2021
DirectDensity™
DirectDensity™
DirectDensity™
100kV, B30s 100kV, F30s
Standard FBP Direct Density
DirectDensity™
DirectDensity™
Varian Eclips
Images for Contouring
( Low-kV / DE etc )
DirectDensity CT30
Breast & Lung Cancer • Female breasts (L/R) • Lungs (L/R) • Whole heart
Prostate Cancer • Bladder • Prostate • Rectum • Femoral heads (L/R)
Deep Learning based Contouring
Cardiac toxicity • Heart chambers (LV, RV, LA, RA) • Aorta
AI-enriched atlas contouring
Head & Neck Cancer
• Brainstem • Parotid Glands • Submandibular Glands • Mandible • Larynx • Eye Globes • Lips
Advanced Lung (SBRT) • Ribs • Aorta • Sternum • Lung lobes (RI, RM,
RS, LI, LS)
RT image Suite
Unrestricted © Siemens Healthineers, 2021 *Optional – Courtesy of Radiologische Allianz, Hamburg, Germany The devices SOMATOM Confidence® RT Pro and syngo.via RT Image Suite VB20 are pending 510(k) clearance and are not yet commercially available in the United States.
4D contouring with syngo.via RT Image Suite* with Direct 4D
Unrestricted © Siemens Healthineers, 2021
Unrestricted © Siemens Healthineers, 2021
Acquisition: Auto OAR Contouring1 triggered at the scanner offers a consistent starting point
1) Optional Courtesy of Radiologische Allianz, Hamburg, Germany
AutoContouring
47
SOMATOM go. Sim : Prostate
1) Optional Courtesy of University Hospital Aarhus, Denmark VRT generated with MM RT Image Suite
100 kV Acquired slices: 32 x 0.6 mm Pitch: 0.8 Rotation time: 0.5 s Scan lengths: 466 mm Scan time: 15 s Slice thickness: 3 mm CTDIvol: 17.19 mGy DLP: 806 mGy*cm
Unrestricted © Siemens Healthineers, 2021 Click to add footnote second line
The future is in motion 640.35 0.6mm
2020110 go Sim/go Open Pro 302ADBZX00008000
85cm 85cmFOV
1
2
3
4
5
6
SOMATOM go.sim
Push the boundaries with shorter scan times for deep inspiration breath-hold
Push the boundaries with shorter scan times for deep inspiration breath-hold
iMAR
iMAR
iMAR
iMAR
15
16
17

20
21
Push the boundaries with intelligent Direct i4D1Potential for smaller target margins
Push the boundaries with intelligent Direct i4D1Potential for smaller target margins
Push the boundaries with intelligent Direct i4D1Potential for smaller target margins
Push the boundaries with intelligent Direct i4D1Potential for smaller target margins
Push the boundaries with intelligent Direct i4D1Potential for smaller target margins
CARE kV
CARE kV
Push the boundaries with TwinSpiral Dual Energy1 Improved spectral separation
Dual Energy Monoenergetic PlusMalignant neoplasm of sinus maxillaris
3 Material DecompositionDual Energy < Monoenergetic Plus >
Dual Energy Monoenergetic PlusMalignant neoplasm of sinus maxillaris
We have two duties
DirectDensity
DirectDensity
DirectDensity™
DirectDensity™
DirectDensity™
4D contouring with syngo.via RT Image Suite* with Direct 4D
Acquisition: Auto OAR Contouring1 triggered at the scanner offers a consistent starting point
SOMATOM go. Sim: Prostate