The California NanoSystems InstituteThe California NanoSystems Institute

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The CNSI at UCLAThe CNSI at UCLA

The CNSI at UCSBThe CNSI at UCSB

UC President (Oakland)

UCSB Chancellor

UCLA Chancellor

UC Regents

CNSI Board of Directors3 UC appointees, 3 Corporate Partner appointees7 academics & private citizensLee Hood, David Baltimore, Ralph Shapiro, Roy Doumani, Peter Preuss, others

CNSI Director & Co-DirectorJim Heath (UCLA) Evelyn Hu (UCSB)

Chief Operating OfficerRoy Doumani (acting)

CNSI Executive CouncilMike Phelps, Chih-Ming Ho, Emily Carter, Sam Gambhir, Owen Witte, David Awschalom, Fraser Stoddart

Faculty (building to ~55 (~30 at UCLA)

The Charter of the CNSI: The Charter of the CNSI: Governance Governance

The Charter of the CNSI: Institute MembersThe Charter of the CNSI: Institute MembersMembers are ladder faculty at UCLA or UCSB whose research activities are consistent with the mission of the CNSI. The hiring of new Institute Members with CNSI FTE will be proposed by the CNSI according to its research needs and objectives, after consultation with the appropriate departments. All individuals appointed with CNSI FTE will be Members, along with at least twenty-five current faculty from various departments at both campuses. Institute Membership may be extended to ladder faculty hired in the future by various departments.

Responsibilities: Members will share responsibility for … the research infrastructure of the Institute, faculty and graduate student recruitment, and interfacing with the industrial partners of CNSI, and teaching Institute courses.

Benefits: Institute Members may occupy space in the Institute building, utilize the CNSI administrative staff, and pursue IP matters (patents, contracts, etc.) through the Institute. Institute Members will also have first access to CNSI graduate students and will be able to utilize the research infrastructure of the Institute, including technical support staff. Members may have access, … , to CNSI matching funds to assist in the acquisition of research instrumentation.

Institute AssociatesInstitute Associates•Institute Associates are individuals whose research goals are related to the mission of the CNSI, who want access to CNSI infrastructure, and with whom Institute Members may wish to work. •The Director or Co-Director and the Institute Executive Committee must approve CNSI Associates. •They may be UCLA or UCSB faculty in the ladder series or in other series, such as In-Residence. •They may be associated with the Institute through corporate or academic partnerships. For example, Visiting Institute Scholars will be considered CNSI Associates. •Institute Associates may be entitled to temporary space in the Institute. •Institute Associates will not have CNSI teaching or administrative responsibilities. •Institute Associates may have access to the research infrastructure of the Institute and are encouraged to participate in CNSI colloquia and short courses.

New Faculty Hires of the CNSI

James K. Gimzewski (Senior Hire) joined CNSI as a Professor in the UCLA Dept. of Chemistry and Biochemistry in January, 2001 after spending over 15 years at IBM’s Zurich Research Laboratory. Jim brings tremendous expertise to the CNSI in the areas of molecular electronics, scanning tunneling microscopy, bio-NEMs devices, and ultra-sensitive nano-scale analytical instrumentation. Jim’s scientific contributions have received international recognition, including the Duddell Medal (2001), Royal Academy of Engineering (2001), The Discover Award for Emerging Fields, (1997), and the Feyman Prize (1997).

Shimon Weiss (Senior Hire) joined CNSI as a jointly appointed Professor in the UCLA Department of Chemistry and Biochemistry, and the UCLA medical school’s Department of Physiology. Shimon spent several years at Lawrence Berkeley Labs developing a host of bio-labeling and spectroscopic techniques for interrogating the form and function of biosystems at the single-protein or cellular level. Shimon’s background in electrical engineering and quantum optics adds to the interesting mix of cross-disciplinary science in CNSI. Shimon’s contributions have been internationally recognized through the Michael and Kate Barany 2001 Biophysical Society Award. He is a founder of Quantum Dot Corporation.

Carlo Montemagno (Senior Hire) Carlo joined CNSI as the Carol and Roy Doumani Professor in UCLA’s Henry Samueli School of Engineering and Applied Science, and as the new co-chair of UCLA’s bioengineering program. Carlo spent the last several years building a world class bio-NEMS and bio-engineering program at Cornell. Among his several contributions has been the development of bio-molecular motor-driven devices on chip-based platforms, and his work has been internationally recognized in both the popular press and through awards, such as the Discover Award.

George ‘Bud’ Homsy (Senior Hire) Having recently joined the Mech. and Env. Eng Dept from Stanford. Bud Homsy’s research interests are in the important areas that comprise microfluidics and interfacial flows.

Tony Evans (Senior Hire) Tony will be joining CNSI from Princeton where he was directing Princeton Materials Institute. Tony’s research program has includes the study of nanocomposite materials, their macroscopic structural properties, and the issues of stability, fatigue and degradation.

Martin Moskovits (Senior Hire) Martin joined the CNSI as a Professor of Chemistry at UCSB, and as Dean of Mathematical and Physical Sciences, coming from the Univ. of Toronto. Martin was an early pioneer in the field of nano, doing seminal work on small metal clusters, as well as on the controlled growth, physics, and transport properties of metallic nanowires

Joan Emma Shea (Junior Hire) recently joined CNSI and the Chemistry Department at UCSB, having been an Assistant Professor at the University of Chicago. Her research focuses on developing and applying techniques of statistical and computational physics to the study of biological problems.

Frank Brown (Junior Hire) joins as an Assistant Professor in UCSB’s Chemistry Department, having served as an NSF Postdoctoral Fellow at UC San Diego and a Yen Fellow at Chicago. Frank will work on issues related to cellular functioning: membrane dynamics, cytoskeletal assembly and the kinetics of enzymatic turnover.

Jianghong Rao (Junior Hire) joins as an Asst Prof in UCLA’s Dept of Mol. and Med. Pharm. after completing a Damon Runyon-Walter Winchell Fellowship in Whitesides’ group at Harvard. Jiang will develop molecular probes for monitoring biological processes in vivo. For example, he is building probes that will enable the direct monitoring of neuronal communication in real time.

Jing Huang (Junior Hire) joined CNSI in UCLA’s Department of Mol. & Med. Pharm. after completing a Howard Hughes Postdoc Fellowship in Shreiber’s lab at Harvard. Her research interests involve the use of whole-genome expression profiling, chemical genetics, and biochemistry to study Tor signal transduction networks and the molecular basis of human diseases/conditions involving this pathway, including cancer, diabetes, neurobiological disorders, and autoimmunity.

The Institute’s ability to interface with the private sector to create licensing and royalty agreements in a manner suited to the pace of discovery and business adaptation is essential to the Institute’s success.

The CNSI will work within UC Intellectual Property (IP) policies .The Institute may retain outside counsel regarding IP matters. Proceeding on this basis will, under Regental policy, require the concurrence of the University’s General Counsel. We anticipate that this concurrence will be obtained promptly and non-controversially if the Institute selects highly credentialed counsel known to the General Counsel. The UCLA Chancellor will seek a delegation of responsibility to give the Director and Co-Director authority to sign final patent applications and agreements after all necessary UC approvals have been received.

Intellectual PropertyIntellectual Property

Ensuring timeliness in UC’s IP negotiation, approval, etc. procedures is a component of the CalISI mandate.

Establishing streamlined prototype procedures is our mutual goal. Accordingly, the UCLA Chancellor will request the UC General Counsel and the UC Senior Vice President-Business and Finance to designate a single individual to serve as the sole liaison for coordination of CNSI Intellectual Property issues and work to establish concrete procedures, including specific timing, deadlines, and responsibilities to expedite the legal and business aspects of intellectual property.

Our objective is to complete contracts within a 60-day period by establishing a timeline that incorporates a 30-day review period with an additional 30-day period, to be used only as necessary, to resolve issues that may arise. In the course of this, the UCLA Chancellor will personally intervene to ensure that the shared objectives of the CNSI, UCLA, UCSB, and UC are achieved.

Expediting Intellectual PropertyExpediting Intellectual Property

Intellectual PropertyIntellectual Property

Four Companies have been started out of the CNSI in the past year

NanoSys (Heath is a founder)LA Tech Center (Phelps is a founder)NanoPhotonics (Yablonovitch is a founder)Santa Barbara Materials, Inc. (Stucky & Chmelka are founders)

+ QDOT (Shimon Weiss); Agensys (Owen Witte); Carbon Nanotechnologies Inc. (Gimzewski)

The HP/CNSI ConnectionThe HP/CNSI Connection>$16M DARPA grants since 1999 (>$8M to HP)6 joint Patents filed over past 3 years:6 joint Patents filed over past 3 years:• 1 patent filed in January, 2002 (reduced to practice at UCLA & UCSB)• 1 Patent Cited as one of Five that will • transform Business & Technology (MIT Tech. Rev., 2001)• 1 Patent that generated world-wide press coverage (Jan. 2002)

6 joint papers over past few years:6 joint papers over past few years: One represented the fundamental architectural paper of modern nanoelectronics (Teramac in Science 1998)

One received worldwide press coverage incl. front page NY Times & represented the birth of modern molecular electronics(Molecular logic, Science 1999)

The HP/CNSI ConnectionThe HP/CNSI Connection>$16M DARPA grants since 1999 (>$8M to HP)6 joint Patents filed over past 3 years:6 joint Patents filed over past 3 years:• 1 patent filed in January, 2002• 1 Patent Cited as one of Five that will • transform Business & Technology (MIT Tech. Rev., 2001)• 1 Patent that generated world-wide press coverage (Jan. 2002)

6 joint papers over past few years:6 joint papers over past few years: One represented the fundamental architectural paper of modern nanoelectronics (Teramac in Science 1998)

One received worldwide press coverage incl. front page NY Times & represented the birth of modern molecular electronics(Molecular logic, Science 1999)

0.5 micrometers0.5 micrometers

State-of-the-Art (Jan 2002)

Now at 2 Now at 2 10 101111 bits/cmbits/cm2 2 !!!!

The HP/CNSI ConnectionThe HP/CNSI Connection

0.5 micrometers0.5 micrometers

State-of-the-Art (Jan 2002)

Now at 2 Now at 2 10 101111 bits/cmbits/cm2 2 !!!!

This work on how to prepare such ultra-high device This work on how to prepare such ultra-high device densitiesdensities

• started with an idea & an experiment from HP

•A refinement of that idea at UCLA

•A demonstration of that new concept by a joint UCSB/UCLA effort

Science, December 21, 2001

FromFrom 5 Patents that will Transform Business and Technology -- MIT Tech Review, 2001MIT Tech Review, 2001

Looks Unconventional, but operates conventionally

•Very low energy consumption•Almost all fabrication carried out at room temperature

Currently working with Steve Edwards (HP Boise) to explore commercialization possibilities

NanoTech is where Biotech was in 1981-85Michael Darby & Lynne Zucker (UCLA Anderson School) preparing nanotech patents & articles CNSI data base at CNSI.

The CNSI as an information resource for the The CNSI as an information resource for the business of nanotechbusiness of nanotech