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Investor Luncheon May 2, 2007

Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

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Page 1: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1

Investor Luncheon

May 2, 2007

Page 2: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

2 2

TODAY’S PRESENTATION CONTAINS FORWARD LOOKING STATEMENTS WHICH EXPRESS THE CURRENT BELIEFS AND EXPECTATIONS OF MANAGEMENT. SUCH STATEMENTS ARE BASED ON CURRENT EXPECTATIONS AND INVOLVE A NUMBER OF KNOWN AND UNKNOWN RISKS AND UNCERTAINTIES THAT COULD CAUSE TEVA’S FUTURE RESULTS, PERFORMANCE OR ACHIEVEMENTS TO DIFFER SIGNIFICANTLY FROM THE RESULTS, PERFORMANCE OR ACHIEVEMENTS EXPRESSED OR IMPLIED BY SUCH FORWARD-LOOKING STATEMENTS. IMPORTANT FACTORS THAT COULD CAUSE OR CONTRIBUTE TO SUCH DIFFERENCES INCLUDE TEVA’S ABILITY TO SUCCESSFULLY DEVELOP AND COMMERCIALIZE ADDITIONAL PHARMACEUTICAL PRODUCTS, THE INTRODUCTION OF COMPETITIVE GENERIC PRODUCTS, THE IMPACT OF COMPETITION FROM BRAND-NAME COMPANIES THAT SELL THEIR OWN GENERIC PRODUCTS OR SUCCESSFULLY EXTEND THE EXLUSIVITY PERIOD OF THEIR BRANDED PRODUCT, TEVA’S ABILITY TO RAPIDLY INTEGRATE THE OPERATIONS OF ACQUIRED BUSINESSES, THE AVAILABILITY OF PRODUCT LIABILITY COVEREGE IN THE CURRENT INSURANCE MARKET, THE IMPACT OF PHARMACEUTICAL INDUSTRY REGULATION AND PENDING LEGISLATION THAT COULD AFFECT THE PHARMACEUTICAL INDUSTRY, THE DIFFICULTY OF PREDICTING U.S. FOOD AND DRUGS ADMINISTRATION (“FDA”) AND OTHER REGULATORY AUTHORITY APPROVALS, THE REGULATORY ENVIRONMENT AND CHANGES IN THE HEALTH POLICIES AND STRUCTURE OF VARIOUS COUNTRIES, ACCEPTANCE AND DEMAND FOR NEW PHARMACEUTICAL PRODUCTS AND NEW THERAPIES, UNCERTAINTIES REGARDING MARKET ACCEPTANCE OF INNOVATIVE PRODUCTS NEWLY LAUNCHED, CURRENTLY BEING SOLD OR IN DEVELOPMENT, THE IMPACT OF RESTRUCTURING OF CLIENTS, RELIANCE ON STRATEGIC ALLIANCES, EXPOSURE TO PRODUCT LIABILITY CLAIMS, DEPENDENCE ON PATENT AND OTHER PROTECTIONS FOR INNOVATIVE PRODUCTS, FLUCTUATIONS IN CURRENCY, EXCHANGE AND INTEREST RATES, OPERATING RESULTS, OTHER FACTORS THAT ARE DISCUSSED IN TEVA’S ANNUAL REPORT ON FORM 20-F AND ITS OTHER FILINGS WITH THE U.S. SECURITIES AND EXCHANGE COMMISSION (“SEC”). FORWARD LOOKING STATEMENTS SPEAK ONLY AS OF THE DATE ON WHICH THEY ARE MADE, AND THE COMPANY UNDERTAKES NO OBLIGATION TO UPDATE PUBLICLY OR REVISE ANY FORWARD LOOKING STATEMENTS, WHETHER AS A RESULT OF NEW INFORMATION, FUTURE DEVELOPMENTS OR OTHERWISE.

Forward-Looking Statements

Page 3: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

3 3

Strong Q1 2007 Performance

Q1/2007Q1/2007 Q1/2006Q1/2006 %Change%Change

Sales ($ Millions)

Net Income ($ Millions)

Earnings per Share (diluted $)

Cash Flow from Operations

P/E Ratio 2007 (F.C. Consensus $2.12)

Market Capitalization (as of May 1, 2007: $38.95) $32B

18

24%

20%

14%

2,080

342

0.42

$499M

1,673

286

0.37

$288M

Page 4: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

4 4

Q1/2007 – Sales By Region

ROW, 2%

Israel, 5%

CEE, 4%,

Latin America,7%

TSP, 5%

Q1/07: $2,080 Million

International

18%Europe*27%

* Western Europe and Hungary

North America

55%

Page 5: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

5 5

Exchange Rates* (Quarterly Average)Exchange Rates* (Quarterly Average)

*Q106= 100%*Q106= 100%

USD:GBPUSD:GBP

USD:HUFUSD:HUF

USD:EUROUSD:EURO

USD:NISUSD:NIS

USD:CADUSD:CAD

Q1/07Q1/07

90%90%(0.51)(0.51)

91%91%(192.29)(192.29)

92%92%(0.76)(0.76)

90%90%(4.21)(4.21)

102%102%(1.17)(1.17)

Q1/06Q1/06100%100%(4.67)(4.67)

100%100%(0.83)(0.83)

100% 100% (0.57)(0.57)

100%100%(211.64)(211.64)

100%100%(1.15)(1.15)

99%99%(1.14)(1.14)

Q4/06Q4/0691%91%

(4.26)(4.26)

92%92%(0.76)(0.76)

95%95%(201.37)(201.37)

91%91%(0.52)(0.52)

Page 6: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

6 6

1,071

881

730

594

427

Q1/03 Q1/04 Q1/05 Q1/06 Q1/07

Q1/2007 – North America Pharmaceutical Sales

($ Millions)

CAGR = 26%

Up 21%

Page 7: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

7

163

231

326

381

521

Q1/03 Q1/04 Q1/05 Q1/06 Q1/07

Q1/2007 – Europe* Pharmaceutical Sales

($ Millions)

CAGR: 34%

* Western Europe and Hungary

Up 37%

Page 8: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

8

80108

131

261

341

Q1/03 Q1/04 Q1/05 Q1/06 Q1/07

Q1/2007 – International (ROW) Pharmaceutical Sales($ Millions)

CAGR = 31%

Up 30%

Page 9: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

9

188

371

501

524

587

283439

543

740

220

148149

2003 2004 2005 2006 Q1/06 Q1/07

API - Internal / Third Party Sales

internalinternalthird partythird party

654

940

369

($ Millions)($ Millions)

1,067

Down 1%

Down 14%

Up 36%Down 9%336

1,327

Up 12%

Up 24%

Page 10: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1010

Q1/2007 – Consolidated Statements of Income

($ Millions)

% ChangeQ1/06(*)

% of SalesQ1/06*Q1/07 Q1/07

* Before non-recurring items, after tax : Q1/2006- $1.29B

Sales

Gross profit

R&D – net

SG&A expenses

Operating income

Financial (expense)

Income before taxes

Net income

Earning per share (diluted)

Tax rate

2,080

1,037

135

456

446

(28)

418

342

0.42

18%

1,673

787

103

316

368

(14)

354

286

0.37

19%

24.3%

31.8%

31.1%

44.3%

21.2%

100%

18.1%

19.6%

13.5%

100%

49.9%

6.5%

21.9%

21.4%

1.3%

20.1%

16.4%

100%

47.0%

6.2%

18.9%

22.0%

0.8%

21.2%

17.1%

Page 11: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

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* Actually distributed ** Net cash provided by operating activities less purchase of property, plant and equipment (net), and dividends paid

Dividends*

Purchase of fixed assets (net of proceeds from sale)

Cash flow from operating activities

Acquisition of companies

Yr 2005

Free cash flow**

Yr 2006

546

2,058

3,587

390

229

1,463

Q1/06Q2/06

(1,009)

288

3,556

71

55

162

1,072

1,370

11

307

162

901

Net Income (loss)

Q3/06

488

212

24

90

57

65

Q1/2007 – Cash Flow Highlights($ Millions)

Q4/06

460

765

5

130

60

575

606

793

2

75

59

659

Q1/07

342

499

-

149

72

278

Page 12: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

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Q1/2007 – Consolidated Balance Sheet

($ Millions)

%%ChangeChange

Mar, 31Mar, 3120072007

Mar, 31Mar, 3120062006

Dec 31,Dec 31,20062006

Current Assets 8,021 7,640 5% 5,862

of which: Inventory 2,084 1,879 11% 1,689

Investments And Other Assets 686 613 12% 633

Property, Plant & Eqmt-net 2,288 2,193 4% 2,063Intangible Assets 1,958 1,987 -1% 2,056Goodwill 8,074 8,038 0% 7,749

Total Assets 21,027 20,471 3% 18,363Current Liabilities 4,641 4,071 14% 3,681

of which: Short Term Debt 1,521 742 105% 1,062

Long Term Liabilities 3,079 2,765 11% 2,853

Minority Interests 36 35 3% 21

Convertible Senior Debentures 1,883 2,458 -23% 2,590

Shareholders’ Equity 11,388 11,142 2% 9,218

Total Liabilities & Equity 21,027 20,471 3% 18,363

Page 13: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

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Q1/2007 – Financial Strength

* Includes both converts of $1.4 bn and straight debt of $1.5 mn issued on Q1/06 ** [DEBT/(Debt+Equity)]

Total Equity 11.39B 11.14B

Total Debt 5.53B 5.33B

of which:

short-term 1.52B 0.74B

long-term 4.01B* 4.59B*

Leverage** 0.33 0.32

Dec 31,2006

Mar 31,2007

($ Billions)

Page 14: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1414

NASDAQ Top 20 CompaniesApril 27, 2007

*

* Share Price: $39.01

1 MSFT Microsoft Corporation 294,944,497,680$ 2 CSCO Cisco Systems, Inc. 163,262,119,020$ 3 INTC Intel Corporation 126,445,363,470$ 4 GOOG Google Inc. 110,218,763,970$ 5 ORCL Oracle Corporation 98,190,483,300$ 6 AAPL Apple Inc. 86,118,550,000$ 7 QCOM QUALCOMM Incorporated 73,930,398,340$ 8 AMGN Amgen Inc. 73,843,239,510$ 9 DELL Dell Inc. 57,312,821,220$ 10 ERIC LM Ericsson Telephone Company 57,055,567,861$ 11 CMCSA Comcast Corporation 55,694,660,110$ 12 EBAY eBay Inc. 46,777,841,580$ 13 YHOO Yahoo! Inc. 38,448,413,220$ 14 GILD Gilead Sciences, Inc. 38,079,552,940$ 15 TEVA Teva Pharmaceutical Industries Limited 30,924,246,877$ 16 INFY Infosys Technologies Limited 29,811,461,640$ 17 SHLD Sears Holdings Corporation 29,520,753,300$ 18 AMAT Applied Materials, Inc. 26,956,174,900$ 19 AMZN Amazon.com, Inc. 25,959,320,079$ 20 ADBE Adobe Systems Incorporated 25,219,405,780$

Page 15: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1515

Source: IMS Health March 2007 NPA

Top U.S. Companies(ranked by # of retail prescriptions)*

Total Rx’s(000’s)

1 Teva USA 430,019

2 Pfizer 290,147

3 Novartis 278,406

4 Mylan 261,507

5 Watson 214,257

6 Barr 135,701

7 Merck 124,783

8 AstraZeneca 118,029

9 GlaxoSmithKline 115,618

10 Mallinkrodt 108,337

(000’s) Total Rx’s

1 Teva USA 422,872

2 Mylan 259,420

3 Watson 214,254

4 Sandoz 198,076

5 Barr 135,590

6 Mallinckrodt 108,337

7 Actavis 88,755

8 Qualitest 75,357

9 Par 71,674

10 Greenstone 64,858

Top U.S. Generic Companies(ranked by # of retail prescriptions)*

Page 16: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1616

Teva… The Leader in Generic Growth…

Teva’s volume change for the quarter represents

25.5% of the generic TRx growth

13.0%48,613422,872TEVA12.3%246,4012,242,971GENERIC MARKET

TRXMAT/3

/07% Chg

TRx Vol Chg MAT 1Q06

vs MAT 1Q07

TRXMAT/3

/07(000s)

3.6%3,837110,0552.6%15,045591,891

TRXQtr/3/

07% Chg

TRx Vol Chg 4Q06 vs

1Q07

TRXQtr/3/

07(000s)

Page 17: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1717

Competitive Generic TRX share*

2.7%Other

2.4%Zydus

4.3%Mallinckrodt

5.8%Aurobindo

8.3%Ranbaxy

24.4%Dr. Reddy – AG

52.1%Teva

Simvastatin # of ANDA’s: 8

0.1%Other

0.1%Ranbaxy

0.3%Cobolt

0.3%Actavis

1.4%Aurobindo

2.1%Lupin

4.7%Apotex

39.5%Teva

51.5%Greenstone – AG

Sertraline # of ANDA’s: 18

0.3%Other

1.0%Par

4.5%Sandoz

9.0%Dr Reddy

13.7%Watson – AG

24.9%Apotex

46.7%Teva

Pravastatin 10/20/40 # of ANDA’s: 9

13%Other

5%Dr Reddy

6%Sandoz

6%Caraco

10%Prasco - AG

10%Watson

15%Mylan

35%Teva

Zolpidem # of ANDA’s: 13

*Week of April 13, 2007

Page 18: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1818

U.S. Generic Industry’s Largest Pipeline

151 ANDAs – over $90 billion in total sales

78 Paragraph IV Filings

42 First-to-File – over $35 billion in total sales

151 ANDAs – over $90 billion in total sales

78 Paragraph IV Filings

42 First-to-File – over $35 billion in total sales

* Including products under the agreement with Andrx and Impax

(As of April 23, 2007)

Page 19: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

1919

Oxycodone

Transition Period

Impax announces plans to exit June

14, 2007

Dec 31, 2007 Endo exits

* The conditions that will determine the timing for Teva’s exit from the market have not yet occurred.

Jan 2008 Teva exits*

Impax right to re-enter?Impax right to re-enter?

Feb 28, 2007 Watson exits

Maximization of opportunity will require additional DEA quota

Plan calls for sales of product at least until the end of 2007

Page 20: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

2020

ProAir HFA Timeline

Validate new HFA Line

April 2006

Purchase of Ivax

Jan. 2006

Announce intent to exit CFC Market

Feb. 2006

Launch of ProAir

July 14, 2006

HFA Production Ramp-up Oct. 2006

Exit CFC Market

July 1, 2006

Schering announces

discontinuation of CFC in early

2007

Page 21: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

2121IMS NPA 4/20/07

SABA Market Weekly TRx (Share)

0%

20%

40%

60%

80%

100%

1-Sep

15

-Sep

29

-Sep

13-Oct

27-Oct

10

-Nov

24

-Nov

8-D

ec

22

-Dec

5-Jan

19-Jan

2-Feb

16

-Feb

2-M

ar

16

-Mar

30

-Mar

13

-Apr

Week

HFAs

CFCs

Page 22: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

2222IMS NPA 4/20/07

SAVA-HFA TRx Market (Share)

0%

10%

20%

30%

40%

50%

60%

70%

80%

1-Sep

15

-Sep

29

-Sep

13-Oct

27-Oct

10

-Nov

24

-Nov

8-D

ec

22

-Dec

5-Jan

19-Jan

2-Feb

16

-Feb

2-M

ar

16

-Mar

30

-Mar

13

-Apr

Week

ProAir HFA

Proventil HFA

Ventolin HFA

Xopenex HFA

Page 23: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

23

495

625

782 916

498394

225

311

2003 2004 2005 2006

Q1/2007 – Copaxone® In-Market Global Sales

($ Millions)

1,176

720

Up 20%

17%

Up 22%936

1,414

26%

USNon US

Q1/06 Q1/07

31%

18%

221260

108

141329

401

Page 24: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

2424

Next Milestone: Submission To FDA - 2008

Next Milestone: Submission To FDA - 2008

Copaxone® 40 mg

• Copaxone®, at a 40 mg/day dose, has the potential to provide better efficacy compared to all approved first-line treatments

• Results of 9-month Phase II study, which compared to Copaxone® 20 mg/day, recently published in Neurology

– Patients taking the higher dose showed a 38% greater reduction in inflammatory disease activity as measured by MRI

– Reduced mean on-trial relapse rate of 77% vs. 62%

• Phase III study (“FORTE”) initiated in July 2006; Recruitment ofapproximately 1,000 patients is expected to be completed in May 2007

Page 25: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

2525

Laquinimod

• A novel, oral product for relapsing MS

• Licensed from Sweden’s Active Biotech

• Results of Phase IIb study presented at this week’s Annual Meeting of the American Academy of Neurology (AAN)

– Demonstrated that an oral 0.6 mg dose of laquinimod given daily significantly reduced MRI disease activity by 38 percent in RRMSpatients

– Favorable trend towards reducing annual relapse rates, the number of relapse-free patients and time to first relapse compared with placebo.

– Confirmed favorable safety profile

• Phase III studies planned to start in the second half of 2007

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Azilect® for Parkinson’s

• First once-daily medication for PD; Only MAO-B inhibitor with an indication for both monotherapy and adjunct therapy

• Launched in 26 countries since initial launch in Israel in early 2005

• AZILECT TRx in March grew significantly faster than the PD market

• Patients are responding positively to the convenient once daily dosing and the good tolerability

• Continue to study AZILECT as a symptomatic therapy (LEGATO) and as a possible disease modifying therapy (ADAGIO) study

Page 27: Teva Q1-2007 Investor Luncheon Presentation FINAL.ppt ...s24.q4cdn.com/720828402/files/doc_downloads/doc_events/Lunche… · other factors that are discussed in teva’s annual report

27

Investor Luncheon

May 2, 2007