6
March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street Utica, NY 13501 1-315-507-4378 [email protected] Re: Testing Data Analysis- 3979 Silicone Element Celliant, 3981 Pennant Celliant, 3976 Clad Celliant, 3977 Gamut Celliant Dear Petra and Steve, At Hologenix, LLC we have dedicated significant resources to develop, test and substantiate our science. Accordingly, Celliant materials submitted for certification undergo extensive and methodical analysis. This is performed in addition to independent clinical trials and physical testing. We have also established a Research and Development Laboratory, which has been approved to collect data and generate original research for the peer-review process and publication of our own results. The Science Advisory Board leads the design and implantation of methods used by the Laboratory. In our lab, we utilize the same machine and protocol used in the clinical studies, a Perimed Periflux System 5000. This machine is widely recognized as the industry standard in the medical field when testing for TCPO2. This system of measuring was initially developed to test for hypoxia, or low tissue oxygen levels, in subjects suffering from diabetes and other circulatory disorders. It is also used to measure the effectiveness of diabetic medication. The lead sensor is heated to 45°C to eliminate any increase in oxygen due to localized warming of the skin tissue. The test lasts three hours and consists of a 90-minute period using a placebo garment followed by a 90-minute period with a Celliant garment. This allows each subject to serve as his/her own control. The subject is seated comfortably with vital signs such as blood pressure, heart rate, and body temperature taken at arrival, after 90-minutes, and then again at the conclusion of the test. At Hologenix, we have the capacity to test 3-4 people per day, and to date we have tested over 1,000 subjects. These subjects are chosen at random using Craigslist.com. All healthy people age 18-70 are welcome. The only requirement is that they be a non-smoker and abstain from alcohol and caffeine the day of testing. We do not screen our subjects based on perceived health. We test every product containing Celliant from fabric to prototypes including: shoes, socks, shirts, pants, jackets, mattress pads, and more before it can enter production. On average, there is an increase in TCPO2 of approximately 7%. This significant increase is the catalyst for the benefits cited by Hologenix. To help generate further awareness and gain valuable feedback, we provide a pair of socks to each subject. In conclusion, Hologenix, LLC rigorously tests each Celliant product to ensure it meets our standards and will perform as expected. Thank you for your interest in our technology Best regards, Testing Department Testing and Product Standards Hologenix, LLC

Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

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Page 1: Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street Utica, NY 13501 1-315-507-4378 [email protected] Re: Testing Data Analysis- 3979 Silicone Element Celliant, 3981 Pennant Celliant, 3976 Clad Celliant, 3977 Gamut Celliant Dear Petra and Steve,

At Hologenix, LLC we have dedicated significant resources to develop, test and substantiate our science. Accordingly, Celliant materials submitted for certification undergo extensive and methodical analysis. This is performed in addition to independent clinical trials and physical testing. We have also established a Research and Development Laboratory, which has been approved to collect data and generate original research for the peer-review process and publication of our own results. The Science Advisory Board leads the design and implantation of methods used by the Laboratory.

In our lab, we utilize the same machine and protocol used in the clinical studies, a Perimed Periflux System 5000. This machine is widely recognized as the industry standard in the medical field when testing for TCPO2. This system of measuring was initially developed to test for hypoxia, or low tissue oxygen levels, in subjects suffering from diabetes and other circulatory disorders. It is also used to measure the effectiveness of diabetic medication.

The lead sensor is heated to 45°C to eliminate any increase in oxygen due to localized warming of the skin tissue. The test lasts three hours and consists of a 90-minute period using a placebo garment followed by a 90-minute period with a Celliant garment. This allows each subject to serve as his/her own control. The subject is seated comfortably with vital signs such as blood pressure, heart rate, and body temperature taken at arrival, after 90-minutes, and then again at the conclusion of the test.

At Hologenix, we have the capacity to test 3-4 people per day, and to date we have tested over 1,000 subjects. These subjects are chosen at random using Craigslist.com. All healthy people age 18-70 are welcome. The only requirement is that they be a non-smoker and abstain from alcohol and caffeine the day of testing. We do not screen our subjects based on perceived health. We test every product containing Celliant from fabric to prototypes including: shoes, socks, shirts, pants, jackets, mattress pads, and more before it can enter production. On average, there is an increase in TCPO2 of approximately 7%. This significant increase is the catalyst for the benefits cited by Hologenix. To help generate further awareness and gain valuable feedback, we provide a pair of socks to each subject. In conclusion, Hologenix, LLC rigorously tests each Celliant product to ensure it meets our standards and will perform as expected. Thank you for your interest in our technology Bestregards,TestingDepartment Testing and Product Standards Hologenix, LLC

Page 2: Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street Utica, NY 13501 1-315-507-4378 [email protected] Re: Testing Data Analysis- 3979 Silicone Element Celliant, 3981 Pennant Celliant, 3976 Clad Celliant, 3977 Gamut Celliant Dear Petra and Steve, After conducting TCPO2 tests on the fabrics sent, (Style: 3979 Silicone Element Celliant, 3981 Pennant Celliant, 3976 Clad Celliant, 3977 Gamut Celliant) against the placebos provided, we found that the samples performed well; having an average increase in TCPO2 of between 7.9%-10.3% during quality control tests. Each fabric was tested twice to ensure repeatability and confirm the results. In conclusion, the Celliant samples (Style: 3979 Silicone Element Celliant, 3981 Pennant Celliant, 3976 Clad Celliant, 3977 Gamut Celliant) passed our certification process allowing your company to proceed accordingly. Thank you for your interest in our technology Best regards, Testing Department Testing and Product Standards Hologenix, LLC

Page 3: Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

70

75

80

85

90

0 10 20 30 40 50 60 70 80 90

tcPO

2 (m

mHg

)

Time (min)0 10 20 30 40 50 60 70 80 90

Placebo 77 78 78 77 78 80 78 79 79 80Celliant 81 83 83 84 85 84 86 86 87 87

03/22/18

DesigntexStyle: 3979 Silicone Element Celliant

Comp: 85% Celliant, 15% Virgin PETFabric Weight: 119 gsmCelliant Content: 101 gramsFace Fabric Weight: 870 gsm

Hologenix, LLC1112 Montana Ave #13

Santa Monica, CA 90403

THE EVOLUTION OF PERFORMANCE TECHNOLOGY

Control Vitals

Skin Temp oC: 32.1Blood Pressure: 122/66

Heart Rate: 74

Celliant Vitals

Skin Temp oC: 32.3

Blood Pressure: 125/72

Heart Rate: 70

Maximum Increase

10.2%

Average Increase

7.9%

Time (Min) Celliant

30 9.0%

60 10.2%

90 8.7%

Celliant Effect:

FTR#-2025Graph #1 of 4

Test Subject

S. Cherry

Age: 48

Sex: Male

Weight: 177 lbs.

Room Temp: 23.3

Page 4: Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

70

80

90

100

0 10 20 30 40 50 60 70 80 90

tcPO

2 (m

mHg

)

Time (min)0 10 20 30 40 50 60 70 80 90

Placebo 82 81 83 82 82 83 83 84 84 83Celliant 86 85 87 89 91 91 91 92 94 94

03/22/18

DesigntexStyle: 3981 Pennant Celliant

Comp: 85% Celliant, 15% Virgin PETFabric Weight: 119 gsmCelliant Content: 101 gramsFace Fabric Weight: 523 gsm

Hologenix, LLC1112 Montana Ave #13

Santa Monica, CA 90403

THE EVOLUTION OF PERFORMANCE TECHNOLOGY

Control Vitals

Skin Temp oC: 33.1Blood Pressure: 125/70

Heart Rate: 68

Celliant Vitals

Skin Temp oC: 32.9

Blood Pressure: 126/72

Heart Rate: 69

Maximum Increase

13.2%

Average Increase

8.8%

Time (Min) Celliant

30 8.5%

60 9.6%

90 13.2%

Celliant Effect:

FTR#-2026Graph #2 of 4

Test Subject

S. Cherry

Age: 48

Sex: Male

Weight: 177 lbs.

Room Temp: 23.3

Page 5: Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

65

70

75

80

0 10 20 30 40 50 60 70 80 90

tcPO

2 (m

mHg

)

Time (min)0 10 20 30 40 50 60 70 80 90

Placebo 69 70 69 69 71 70 70 70 69 69

Celliant 75 75 76 75 77 76 76 76 76 75

03/22/18

DesigntexStyle: 3976 Clad Celliant

Comp: 85% Celliant, 15% Virgin PETFabric Weight: 119 gsmCelliant Content: 101 gramsFace Fabric Weight: 228 gsm

Hologenix, LLC

1112 Montana Ave #13

Santa Monica, CA 90403

THE EVOLUTION OF PERFORMANCE TECHNOLOGY

Control Vitals

Skin Temp oC: 30.9

Blood Pressure: 112/86

Heart Rate: 72

Celliant Vitals

Skin Temp oC: 31.8

Blood Pressure: 114/87

Heart Rate: 70

Maximum Increase

10.1%

Average Increase

8.7%

Time (Min) Celliant

30 8.7%

60 8.5%

90 8.7%

Celliant Effect:

FTR#-2027Graph #3 of 4

Test Subject

S. Lopez

Age: 25

Sex: Female

Weight: 143 lbs.

Room Temp: 23.3

Page 6: Testing and Product Standards Hologenix, LLC - Designtex Celliant · 2020. 3. 3. · March 22nd, 2018 Designtex Enviromental Composites, Inc Steve Copperwheat 2200 Bleecket Street

50

60

70

80

0 10 20 30 40 50 60 70 80 90

tcPO

2 (m

mHg

)

Time (min)0 10 20 30 40 50 60 70 80 90

Placebo 63 64 66 65 65 66 65 65 65 66Celliant 71 71 70 71 72 72 71 72 73 74

03/22/18

DesigntexStyle: 3977 Gamut Celliant

Comp: 85% Celliant, 15% Virgin PETFabric Weight: 119 gsmCelliant Content: 101 gramsFace Fabric Weight: 288 gsm

Hologenix, LLC1112 Montana Ave #13

Santa Monica, CA 90403

THE EVOLUTION OF PERFORMANCE TECHNOLOGY

Control Vitals

Skin Temp oC: 32.9Blood Pressure: 121/68

Heart Rate: 63

Celliant Vitals

Skin Temp oC: 32.4

Blood Pressure: 127/72

Heart Rate: 67

Maximum Increase

12.7%

Average Increase

10.3%

Time (Min) Celliant

30 9.2%

60 9.2%

90 12.1%

Celliant Effect:

FTR#-2028Graph #4 of 4

Test Subject

A. Lyons

Age: 27

Sex: Female

Weight: 133 lbs.

Room Temp: 23.3