April 2014 Volume 30, Number 4

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Viewpoint

377 Are the ACC/AHA Guidelines on theTreatment of Blood Cholesterol aGame Changer? A Perspective Fromthe Canadian Cardiovascular SocietyDyslipidemia Panel

Todd J. Anderson, MD, Jean Gr�egoire, MD, Robert A.Hegele, MD, Patrick Couture, MD, PhD, G.B. JohnMancini, MD, Ruth McPherson, MD, PhD, Gordon A.Francis, MD, Paul Poirier, MD, PhD, David C. Lau, MD,PhD, Steven Grover, MD, Jacques Genest, Jr., MD, Andr�e C.Carpentier, MD, Robert Dufour, MD, Milan Gupta, MD,Richard Ward, MD, Lawrence A. Leiter, MD, Eva Lonn,MD, Dominic S. Ng, MD, PhD, Glen J. Pearson, PharmD,Gillian M. Yates, MN, NP, James A. Stone, MD, PhD, andEhud Ur, MB

381 Recent Advances in Antidotes forDirect Oral Anticoagulants: TheirArrival Is Imminent

Mandy N. Lauw, MD, Michiel Coppens, MD, and John W.Eikelboom, MBBS

ublication Mail Agreement 41536048eturn undeliverable Canadian addresses to:rans continental Printing, 737 Moray St,innipeg, MB R3J 3S9 Printed in Canada

On the Cover: Intraoperative photograph during pericardial patchrepair of atrioesophageal fistula, a rare and potentially lethalcomplication of atrial fibrillation ablation. From Figure 3 of Nairet al., pages 388-395 of this issue.

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Editorial

385 Comparing the ‘New’ R2CHADS2With the ‘Old’ CHA2DS2-VAScScores for PredictingThromboembolism in PatientsUndergoing Atrial FibrillationAblation: New Does Not MeanBetter

Jelena Kornej, MD, and Gregory Y.H. Lip, MD

Review

388 Atrioesophageal Fistula in the Eraof Atrial Fibrillation Ablation: AReview

Girish M. Nair, MBBS, MSc, FRCPC, Pablo B. Nery, MD,Calum J. Redpath, MBBS, PhD, MRCP, Buu-Khanh Lam,MD, CM, MPH, FRCSC, and David H. Birnie, MB, ChB,MD, MRCP

396 Next-Generation Airbags and thePossibility of Negative Outcomes Dueto Thoracic Injury

Rami N. Khouzam, MD, FACC, FACP, FASNC, FASE,FSCAI, Saleem Al-Mawed, MD, Victor Farah, MD, and AdamMizeracki, MD

Continued

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Table of Contents

Clinical Research -Electrophysiology

405 R2CHADS2 Score and

Thromboembolic Events AfterCatheter Ablation of AtrialFibrillation in ComparisonWith the CHA2DS2-VASc Score

Tze-Fan Chao, MD, Yenn-Jiang Lin, MD, Shih-LinChang, MD, Li-Wei Lo, MD, Yu-Feng Hu, MD,Ta-Chuan Tuan, MD, Jo-Nan Liao, MD, Fa-PoChung, MD, Ming-Hsiung Hsieh, MD, andShih-Ann Chen, MD

413 Left Ventricular Lead Position andOutcomes in the Resynchronization-Defibrillation for Ambulatory HeartFailure Trial (RAFT)

Stephen B. Wilton, MD, MSc, Derek V. Exner, MD, MPH,Jeffrey S. Healey, MD, MSc, David Birnie, MD, MalcolmO. Arnold, MD, John L. Sapp, MD, Bernard Thibault,MD, Christopher S. Simpson, MD, Stanley Tung, MD,Eugene Crystal, MD, Soori Sivakumaran, MD, YaarivKhaykin, MD, Elizabeth Yetisir, MSc, George Wells, PhD,and Anthony S.L. Tang, MD, FHRS; for the RAFTInvestigators

Clinical Research -Imaging

420 Optical Coherence Tomography-Guided

Primary Percutaneous CoronaryIntervention in ST-Segment ElevationMyocardial Infarction Patients: A PilotStudy

Pavel �Cervinka, MD, Radim �Spa�cek, MD, Marian Bystro�n,MD, Martin Kva�s�nák, MD, Andrej Kupec, MD, Michaela�Cervinková, MD, and Petr Kala, MD

A4 ONL

428 Lower Blood Vitamin D Levels AreAssociatedWith an Increased Incidenceof Contrast-Induced Nephropathy inPatients Undergoing CoronaryAngiography

Irfan Sahin, MD, Baris Gungor, MD, Mehmet Mustafa Can,MD, Ilhan Ilker Avci, MD, Gamze Babur Guler, MD, ErtugrulOkuyan, MD, Halil Biter, MD, Suleyman Sezai Yildiz, MD,Burak Ayca, MD, Seckin Satilmis, MD, and Mustafa HakanDinckal, MD

Clinical Research - Prevention

434 Intensive Lifestyle InterventionImproves Cardiometabolic andExercise Parameters in MetabolicallyHealthy Obese and MetabolicallyUnhealthy Obese Individuals

Claudie Dalzill, BSc, Anil Nigam, MD, Martin Juneau, MD,Val�erie Guilbeault, Bsc, Elise Latour, Bsc, Pascale Mauriège,PhD, and Mathieu Gayda, PhD

Clinical Research -Cardiomyopathy

441 Comparison of the Prevalence, ClinicalFeatures, and Long-term Outcomes of

Midventricular Hypertrophy vs ApicalPhenotype in Patients WithHypertrophic Cardiomyopathy

Chi Cai, PhD, Fu-jian Duan, PhD, Yin-jian Yang, PhD,Xi-ying Guo, PhD, Yan-ling Liu, PhD, Yu-qing Liu, PhD,Li-rong Yan, PhD, Zhi-min Xu, PhD, Shi-hua Zhao, PhD,Wei Hua, PhD, Yi-shi Li, PhD, and Chao-mei Fan, PhD

Systematic Review/Meta-analysis

448 Caffeine Intake and Atrial FibrillationIncidence: Dose Response Meta-analysis of Prospective Cohort Studies

Min Cheng, MD, PhD, Zunsong Hu, PhD, Xiangfeng Lu, PhD,Jianfeng Huang, MD, and Dongfeng Gu, MD, PhD

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Table of Contents

455 A Systematic Review of the DiagnosticAccuracy of Cardiovascular MagneticResonance for PulmonaryHypertension

Ning Wang, MD, Xiaolan Hu, MPH, Chenjing Liu, MD, BihiAli, MD, Xiaojuan Guo, MD, Min Liu, MD, PhD, XiaoxiaPeng, MD, PhD, and YuanHua Yang, MD, PhD

Case Report

464 Spontaneous Coronary ArteryDissection Associated With b-HCGInjections andFibromuscularDysplasia

Mathieu Lempereur, MD, Jasmine Grewal, MD, and JacquelineSaw, MD

464 Pedunculated Aortic Mural ThrombusAttached at Unusual Site of NormalAorta Presenting With AcuteMyocardial Infarction

Jin-Sun Park, MD, Byoung-Joo Choi, MD, Joon-Han Shin,MD, You-Sun Hong, MD, So-Yeon Choi, MD, PhD,Myeong-Ho Yoon, MD, PhD, Gyo-Seung Hwang, MD, PhD,and Seung-Jea Tahk, MD, PhD

464 Pure Right Ventricular InfarctionResulting from Coronary Ectasia:Importance of Diagnostic Imaging

Julia A. Palfy, MD, Marta Tomás, MD, Jerónimo Farr�e, MD,PhD, FESC, Miguel A. Navas, MD, Felipe Navarro, MD, PhD,Miguel Orejas, MD, and Angeles Franco, MD, PhD

Images in Cardiology

464 Optical Coherence TomographyImaging of Takayasu CoronaryArteritis

Myriam Amsallem, MD, Patrick Henry, MD, PhD, andSt�ephane Manzo Silberman, MD

A6 ONL

464 Plaque Rupture Within a 16-Year-Old,Bare-Metal Coronary Stent

Paul D. Williams, BM, BCh, MD, MA, Peter Barlis, MBBS,PhD, FRACP, Sonny Palmer, MBBS, FRACP, and RobertWhitbourn, MBBS, FRACP

465 Left Atrial Myxoma: A Rare Cause ofDyspnea

Ali Pourdjabbar, MD, Benjamin Hibbert, MD, Ronnen Maze,MD, Chi Lai, MD, and Michel R. Le May, MD

465 Surgical Rescue of EmbolizedAmplatzer Septal Occluder

Tomás Francisco Cianciulli, MD, FACC, H�ector JorgeRedruello, MD, Miguel Angel Rubio, MD, Ricardo Luis PovedaCamargo, MD, Miguel Angel Granja, MD, Carlos ManuelBarrero, MD, FACC, and Víctor Miguel Mauro, MD

465 Thrombus Formation in the Left AtrialAppendage During Catheter Ablationfor Atrial Fibrillation Under SufficientHeparinization

Takehiro Kimura, MD, PhD, Seiji Takatsuki, MD, PhD,Kojiro Tanimoto, MD, PhD, Yoshinori Katsumata, MD, PhD,Takahiko Nishiyama, MD, PhD, Kohei Inagawa, MD, PhD,Nobuhiro Nishiyama, MD, PhD, Yoko Tanimoto, MD, PhD,Yoshiyasu Aizawa, MD, PhD, and Keiichi Fukuda, MD, PhD

IN

Letters to the Editor

465 It Is Urgent to Investigate Predictors ofthe Response of Blood Pressure toRenal Denervation

Yutang Wang, PhD

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Table of Contents

465 Are Drastic Caloric Restrictions andModerate-Intensity Physical ActivityStill Relevant Lifestyle Interventions forObese Patients With Type 2Diabetes?

S�ebastien Lacroix, MSc, Anil Nigam, MD, Martin Juneau, MD,and Mathieu Gayda, PhD

465 Erysipelas and Myocarditis

Julie Lynn Friedman, MD, Caitlin Toomey, MD, Ignacio A.Echenique, MD, and Egon Ozer, MD, PhD

A8 ONL

465 Chelation in Suspected ProstheticHip-Associated Cobalt Toxicity

Andrea Giampreti, MD, Davide Lonati, MD, and CarloAlessandro Locatelli, MD

Departments

A10 Information for Readers

A14 Announcement: Focus Issue on TheObesity Epidemic: Implications andApproaches

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