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Volume 20, Number 3, March 2014
THE BOTTOM LINE291 A ‘‘Window of Opportunity’’ for Patients with Late-Onset Pulmonary
Dysfunction after Allogeneic Hematopoietic Cell TransplantationKenneth R. Cooke292 Antithymocyte Globulin in Reduced-Intensity Conditioning
Allografting: Is the Benefit Simply in the Eyes of the Transplanter?Mehdi HamadaniREVIEW
295 Optimizing Autologous Stem Cell Mobilization Strategies to Improve
Patient Outcomes: Consensus Guidelines and RecommendationsSergio Giralt, Luciano Costa, Jeffrey Schriber, John DiPersio, Richard Maziarz,John McCarty, Paul Shaughnessy, Edward Snyder, William Bensinger,Edward Copelan, Chitra Hosing, Robert Negrin, Finn Bo Petersen, Damiano Rondelli,Robert Soiffer, Helen Leather, Amy Pazzalia, Steven DevineBIOLOGY
309 FLT3L and Plerixafor Combination Increases Hematopoietic Stem
Cell Mobilization and Leads to Improved Transplantation OutcomeShun He, Jianhong Chu, Sumithira Vasu, Youcai Deng, Shunzong Yuan,Jianying Zhang, Zhijin Fan, Craig C. Hofmeister, Xiaoming He, Henry C. Marsh,Steven M. Devine, Jianhua YuCLINICAL RESEARCH
314 HLA-Haploidentical Donor Lymphocyte Infusions for Patients
with Relapsed Hematologic Malignancies after RelatedHLA-Haploidentical Bone Marrow TransplantationAmer M. Zeidan, Patrick M. Forde, Heather Symons, Allen Chen, B. Douglas Smith,Keith Pratz, Hetty Carraway, Douglas E. Gladstone, Ephraim J. Fuchs, Leo Luznik,Richard J. Jones, Javier Bola~nos-Meade319 Secondary Monoclonal Gammopathy of Undetermined Significance Is
Frequently Associated with High Response Rate and SuperiorSurvival in Patients with Plasma Cell DyscrasiasDehui Zou, Gang An, Guoqing Zhu, JinhongWang, Lihui Shi, Hengxing Meng, Yan Xu,Weiwei Sui, Shuhui Deng, Fenghuang Zhan, Lugui Qiu326 A Novel Reduced-Intensity Conditioning Regimen for Unrelated
Umbilical Cord Blood Transplantation in Children withNonmalignant DiseasesSuhag H. Parikh, Adam Mendizabal, Cara L. Benjamin, Krishna V. Komanduri,Jeyaraj Antony, Aleksandra Petrovic, Gregory Hale, Timothy A. Driscoll, Paul L. Martin,Kristin M. Page, Ketti Flickinger, Jerelyn Moffet, Donna Niedzwiecki,Joanne Kurtzberg, Paul SzabolcsContinued
Contents, continued
337 Pulmonary Symptoms Measured by the National Institutes of Health
Lung Score Predict Overall Survival, Nonrelapse Mortality, andPatient-Reported Outcomes In Chronic Graft-Versus-Host DiseaseJeanne Palmer, Kirsten Williams, Yoshihiro Inamoto, Xiaoyu Chai, Paul J. Martin,Linus Santo Tomas, Corey Cutler, Daniel Weisdorf, Brenda F. Kurland,Paul A. Carpenter, Joseph Pidala, Steven Z. Pavletic, William Wood, David Jacobsohn,Sally Arai, Mukta Arora, Madan Jagasia, Georgia B. Vogelsang, Stephanie J. Lee345 Fludarabine and Exposure-Targeted Busulfan Compares Favorably
with Busulfan/Cyclophosphamide-Based Regimens in PediatricHematopoietic Cell Transplantation: Maintaining Efficacy withLess ToxicityI.H. Bartelink, E.M.L. van Reij, C.E. Gerhardt, E.M. van Maarseveen, A. de Wildt,B. Versluys, C.A. Lindemans, M.B. Bierings, Jaap Jan Boelens354 A Phase II Study of a Nonmyeloablative Allogeneic Stem Cell
Transplant with Peritransplant Rituximab in Patients with B CellLymphoid Malignancies: Favorably Durable Event-Free Survival inChemosensitive PatientsCraig S. Sauter, Juliet N. Barker, Lauren Lechner, Junting Zheng, Sean M. Devlin,Esperanza B. Papadopoulos, Miguel-Angel Perales, Ann A. Jakubowski,Jenna D. Goldberg, Guenther Koehne, Izaskun Ceberio, Sergio Giralt,Andrew D. Zelenetz, Craig H. Moskowitz, Hugo Castro-Malaspina361 Cytokine and Chemokine Patterns Across 100 Days after
Hematopoietic Stem Cell Transplantation in ChildrenJoseph DiCarlo, Rajni Agarwal-Hashmi, Ami Shah, Paul Kim, Laila Craveiro,Renna Killen, Yael Rosenberg-Hasson, Holden Maecker370 Antithymocyte Globulin in Reduced-Intensity Conditioning Regimen
Allows a High Disease-Free Survival Exempt of Long-Term ChronicGraft-versus-Host DiseaseRaynier Devillier, Sabine F€urst, Jean El-Cheikh, Luca Castagna, Samia Harbi,Angela Granata, Roberto Crocchiolo, Claire Oudin, Bilal Mohty, Reda Bouabdallah,Christian Chabannon, Anne-Marie Stoppa, Aude Charbonnier,Florence Broussais-Guillaumot, Boris Calmels, Claude Lemarie, J�erome Rey,Norbert Vey, Didier Blaise375 Treatment of Graft versus Host Disease with Mesenchymal Stromal
Cells: A Phase I Study on 40 Adult and Pediatric PatientsMartino Introna, Giovanna Lucchini, Erica Dander, Stefania Galimberti, Attilio Rovelli,Adriana Balduzzi, Daniela Longoni, Fabio Pavan, Francesca Masciocchi,Alessandra Algarotti, Caterina Mic�o, Anna Grassi, Sara Deola, Irene Cavattoni,Giuseppe Gaipa, Daniela Belotti, Paolo Perseghin, Matteo Parma, Enrico Pogliani,Josee Golay, Olga Pedrini, Chiara Capelli, Sergio Cortelazzo, Giovanna D’Amico,Andrea Biondi, Alessandro Rambaldi, Ettore BiagiContinued
Contents, continued
382 CD341-Selected Stem Cell Boost without Further Conditioning for
Poor Graft Function after Allogeneic Stem Cell Transplantation inPatients with Hematological MalignanciesEvgeny Klyuchnikov, Jean El-Cheikh, Andreas Sputtek, Michael Lioznov,Boris Calmels, Sabine Furst, Christian Chabannon, Roberto Crocchiolo,Claude Lemari�e, Catherine Faucher, Ulrike Bacher, Haefaa Alchalby,Thomas St€ubig, Christine Wolschke, Francis Ayuk, Marie-Luise Reckhaus,Didier Blaise, Nicolaus Kr€oger387 Symptom Distress Predicts Long-Term Health and Well-Being in
Allogeneic Stem Cell Transplantation SurvivorsMargaret F. Bevans, Sandra A. Mitchell, John A. Barrett, Michael R. Bishop,Richard Childs, Daniel Fowler, Michael Krumlauf, Patricia Prince,Nonniekaye Shelburne, Leslie Wehrlen, Li Yang396 Single-Unit Cord Blood Transplantation after Granulocyte
Colony-Stimulating Factor–Combined Myeloablative Conditioningfor Myeloid Malignancies Not in RemissionTakaaki Konuma, Seiko Kato, Jun Ooi, Maki Oiwa-Monna, Yasuhiro Ebihara,Shinji Mochizuki, Koichiro Yuji, Nobuhiro Ohno, Toyotaka Kawamata, Norihide Jo,Kazuaki Yokoyama, Kaoru Uchimaru, Shigetaka Asano, Arinobu Tojo,Satoshi Takahashi402 Hematopoietic Cell Transplant Comorbidity Index Is Predictive of
Survival after Autologous Hematopoietic Cell Transplantation inMultiple MyelomaAyman Saad, Anuj Mahindra, Mei-Jie Zhang, Xiaobo Zhong, Luciano J. Costa,Angela Dispenzieri, William R. Drobyski, Cesar O. Freytes, Robert Peter Gale,Cristina J. Gasparetto, Leona A. Holmberg, Rammurti T. Kamble, Amrita Y. Krishnan,Robert A. Kyle, David Marks, Taiga Nishihori, Marcelo C. Pasquini,Muthalagu Ramanathan, Sagar Lonial, Bipin N. Savani, Wael Saber, Manish Sharma,Mohamed L. Sorror, Baldeep M. Wirk, Parameswaran N. Hari409 NOD2/CARD15 Single Nucleotide Polymorphism 13 (3020insC) is
Associated with Risk of Sepsis and Single Nucleotide Polymorphism8 (2104C.T) with Herpes Viruses Reactivation in Patients afterAllogeneic Hematopoietic Stem Cell TransplantationEmilia Jaskula, Andrzej Lange, Slawomira Kyrcz-Krzemien, Miroslaw Markiewicz,Monika Dzierzak-Mietla, Wieslaw Wiktor Jedrzejczak, Przemyslaw Czajka,Monika Mordak-Domagala, Janusz Lange, Anna Gronkowska, Jacek Nowak,Krzysztof Warzocha, Andrzej Hellmann, Jerzy Kowalczyk, Katarzyna Drabko,Jolanta Gozdzik, Sylwia Mizia, on behalf of the Polish Donor-RecipientMatching Group415 Predictors and Impact of Thirty-Day Readmission on Patient
Outcomes and Health Care Costs after Reduced-ToxicityConditioning Allogeneic Hematopoietic Cell TransplantationSherri Rauenzahn, Quoc Truong, Aaron Cumpston, Londia Goff, Sonia Leadmon,Kim Evans, Jianjun Zhang, Sijin Wen, Michael Craig, Mehdi Hamadani,Abraham S. KanateContinued
Contents, continued
BRIEF ARTICLES
421 Does Total Body Irradiation Conditioning Improve Outcomes of
Myeloablative Human Leukocyte Antigen–Identical SiblingTransplantations for Chronic Lymphocytic Leukemia?Mitchell Sabloff, Ronald M. Sobecks, Kwang Woo Ahn, Xiaochun Zhu,Marcos de Lima, Jennifer R. Brown, Yoshihiro Inamoto, H. Kent Holland,Mahmoud D. Aljurf, Mary J. Laughlin, Rammurti T. Kamble, Jack W. Hsu,Baldeep M. Wirk, Matthew Seftel, Ian D. Lewis, Mukta Arora, Edwin P. Alyea,Matt E. Kalaycio, Jorge Cortes, Richard T. Maziarz, Robert Peter Gale, Wael Saber425 Hematopoietic Stem Cell Transplantation in Children and Young
Adults with Secondary Myelodysplastic Syndrome and AcuteMyelogenous Leukemia after Aplastic AnemiaAyami Yoshimi, Brigitte Strahm, Irith Baumann, Ingrid Furlan, Stephan Schwarz,Andrea Teigler-Schlegel, Joachim-Ulrich Walther, Brigitte Schlegelberger,Gudrun G€ohring, Peter N€ollke, Monika F€uhrer, Charlotte M. Niemeyer430 Serial Profile of Vitamins and Trace Elements during the Acute Phase
of Allogeneic Stem Cell TransplantationYasuhito Nannya, Akihito Shinohara, Motoshi Ichikawa, Mineo Kurokawa