Embed Size (px)
Citation preview
. . . 40(2) 472-485 (2555) KKU Sci. J. 40(2) 472-485 (2012)
Synthesis of Magnetic Polymer Composite Particles
ABSTRACTMagnetic polymer composite particle has received considerable attention due to their
extensive applications in the fields of biomedicine, bioengineering and environment. This articlesummarizes recent works on various techniques used to prepare magnetic polymer compositeparticles. Possible shape of such materials particle is also briefly classified. The discussionfocuses on three famous techniques which are coating method, interface deposition andmonomer polymerization. Special notice is paid to fabrication mechanism and process ofmagnetic polymer composite particle with controlled shape, size and functional properties. Thepotential applications of magnetic polymer composite particles are briefly discussed as well.
:Keywords: Composite particle, Polymer, Magnetic substance
1 . 12110E-mail: [email protected]
473
(polymer composite)(hybrid polymer)
(biomedicine) (bio-engineering) (cell isolation
(protein purification)(enzyme immobilization
(drug delivery)(Fe, Co, Ni
alloy) (ferrite: CoFe2O4, (Mn-Zn)Fe2O4 ) (CrO2)
(Fe4N) (Fe2O3
Fe3O4)
(Bo et al.,2007)
(shell)
(1)(core) (2)
(reverse core-shell) (3)
(4)
1
(coating method)(interface deposition)
(monomer polymerization)
KKU Science Journal Volume 40 Number 2474 Review
1 4 (a) (core-shell) (b)(reverse core-shell) (c) - (interlayered) (d)
(random dispersion) (Zhang et al., 2009)
(Coating method)
(
(Van der Waals forces) /(hydrogen bonding) (morphology)
(
2(Denkbas et al., 2002)
(nonionic emulsifier: Tween 80)(liquid petroleum)(petroleum ether)
(
(crosslinking agent: glutaraldehyde)
(100-250
(polyvinylalcohol; PVA) ( 1-10 )(Xue et al., 2001) (polymethyl methacrylate; PMMA) (300 ) (Denizle et al., 2000)
(polyelectrolyte) (Shchukin et al.,2003)
(a) (b) (c) (d)
475
(Interfacedeposition)
(
- (polystyrene-cobolt ferrite; PS-CoFe2O4) (Li et al., 2009)
heterocoaggulation
3 (b)
3 (a)PS-CoFe2O4 4
(Nakamura et al., 2010)
(layer-by-layer)(melamine-formaldehyde: MF)
-(poly(sodium-p-styrene sulfonate); PSS)
(poly(allylaminehydrochloride); PAH)
(Pd)
MF5
6
PS/FeO4/Au (Bizdoaca andSpasova, 2003) [Fe3O4/PAH]/PS (Caruso et al.,1999) magnetite-coated PS (Spasova etal., 2005)
(Monomerpolymerization)
KKU Science Journal Volume 40 Number 2476 Review
1. (suspension polymerization)
(emulsifier)
(
-(epoxy) (Liu et al., 2003)(Chen et al., 2008)
7
2(a) (b) (Elaissari et al., 2003)
477
3 heterocoaggulation (a)(b) (Li et al., 2009)
4 PS-CoFe2O4 heterocoaggulation(a) (b)
(Li et al., 2009)
5 (Nakamura et al., 2010)
KKU Science Journal Volume 40 Number 2478 Review
6 (a)MF (b) (scale bar 1 µm)
(c) MF (Nakamura et al.,2010)
7 (a) (b)(Chen et al., 2008)
2. (dispersion polymerization)
(continuous phase)
()
() / ( poly(styrene-
glucidylmethacrylate)/Fe3O4 composite microspheres) (Zhang et al., 2009)
(vinyltri-ethoxysilane)(silane coupling agent)
(oleic acid)
479
/
8
(polymaleic anhydride-co-metha-crylicacid) (Fan et al., 2009(Ma et al., 2005)
8 ( )/(Zhang et al., 2009)
3. (emulsion polymerization)
(micellar nucleation)(homogeneous nucleation) ( , 2554)
(criticalmicelle concentration; CMC)
(critical chain length; Jcrit)(
(
KKU Science Journal Volume 40 Number 2480 Review
(Zhang et al.,2009)
(1, 1- (1,1-
diphenylethene; DPE))
( )(
)
DPE
9
10
(divinylbenzene; DVB) (Boguslavsky and Margel, 2008)
- (N-isopropylacrylamide; NIPAM) (Deng et al., 2003)
(Menshikova etal., 2007)
(Wang et al.)
(Xiet al., 2007)
()
9controlled/living radical polymerization (DPE)(Zhang et al., 2009)
481
10 (a) (b)(c)
(Zhang et al., 2009)
11(emulsifier-free miniemulsion polymerization) (Lu et al.,
2007)
4. (miniemulsion polymerization)
(hydrophobe)
(ultrasonication)(Lu et al.,
2007)
(Liu et al., 2004)
KKU Science Journal Volume 40 Number 2482 Review
(40%) (Ramirez and Landfester, 2003)
(DNA)(RNA)
(Bo et al., 2007, Elaissari et
al., 2004)
(biomolecules) (Elaissari et al., 2004)12
(biological sample)
(sorbent)
(Denizle et al., 2000)(Fang et al., 2005)
12 (Elaissari et al., 2004)
483
(
2554).
30(2):
Bizdoaca E.L. and Spasova M.F. (2003). Self-assembly and magnetism in core-shell microspheres. J Vac Sci Technol.21(4): 1515-1518.
Bo Z., Jianmin X. and Huizhou L. (2007).Preparation and application ofmagnetic microsphere carriers. FrontChem Eng China. 1(1): 96-101.
Boguslavsky Y. and Margel S. (2008). Synthesisand characterization of poly(divinyl-benzene)-coated magnetic iron oxidenanoparticles as precursor for theformation of air-stable carbon-coatediron crystalline nanoparticles. JColloid Interf Sci. 317: 101-114.
Caruso F., Susha A.S., Giersig M. and MöhwaldH. (1999). Magnetic core-shell parti-cles: preparation of magnetitemultilayers on polymer latex micro-spheres. Adv Mater. 11(11): 950-953.
Chen Y.-H., Liu Y.-Y., Lin R.-H. and Yen F.-S.(2008). Characterization of magneticpoly(methyl methacrylate) micro-spheres prepared by the modifiedsuspension polymerization. J ApplPolym Sci. 108: 583-590.
Deng Y., Yang W., Wang C. and Fu S. (2003). Anovel approach for preparation ofthermoresponsive polymer magneticmicrospheres with core-shell struc-ture. Adv Mater. 15(20): 1729-1732.
Denizle A., Ozkan G. and Arica M.Y. (2000).Preparation and characterization ofmagnetic polymethylmethacrylatemicrobeads carrying ethylene diaminefor removal of Cu(II), Cd(II), Pb(II) andHg(II) from aqueous solutions. J ApplPolym Sci. 78: 81-89.
Denkbas E.B., Kilicay E., Birlikseven C. andOzturk E. (2002). Magnetic chitosanmicrospheres: preparation and charac
KKU Science Journal Volume 40 Number 2484 Review
terization. React Funct Polym. 50:225-232.
Elaissari A., Sauzedde F., Montagne F. andPichot C. (2003) Preparation ofmagnetic latices. In: Elaissari A, editor.Colloidal polymers synthesis andcharacterization. New York: MarcelDekker
Elaissari A., Veyret R., Mandrand B. andChatterjee J. (2004). Biomedic.alapplication for magnetic latexes. In:Elaissari A, editor. Colloidal biomole-cules, biomaterials, and biomedicalapplications. New York: MarcelDekker.
Fang B., Wang G.F. and Zhang W.Z. (2005).Fabrication of Fe3O4 nanoparticlesmodified electrode and its application for voltammetric sensing ofdopamine. Electroanal. 17(9): 744-748.
Li Y., Yin D., Wang Z., Li B. and Xue G. (2009).Controlling the heterocoagulationprocess for fabricating PS-CoFe2O4nanocomposite particles. ColloidSurface A. 339: 100-105.
Liu X.Q., Guan Y.P., Xing J.M., Ma Z.Y. and LiuH.Z. (2003). Synthesis and propertiesof micron-size magnetic polymerspheres with epoxy groups. Chinese JChem Eng. 11(6):731–735.
Liu X.Q., Guan Y.P., Ma Z.Y. and Liu H.Z.(2004). Surface modification and
characterization of magnetic polymernanospheres prepared by miniemulsion polymerization. Langmuir.20(23): 10278-10282.
Lu S., Ramos J. and Forcada J. (2007). Self-stabilized magnetic polymeric com-posite nanoparticles by emulsifier-free miniemulsion polymerization.Langmuir. 23: 12893-12900.
Menshikova A.Y., Shabsel’s B.M., Skurkis Y.O.,Inkin K.S., Chekina N.A. and IvanchevS.S. (2007). Magnetic polymerparticles: synthesis and properties.Russ J Gen Chem. 77(3): 354-362.
Nakamura M., Katagiri K. and Koumoto K.(2010). Preparation of hybrid hollowcapsules formed with Fe3O4 andpolyelectrolytes via the layer-by-layerassembly and the aqueous solutionprocess. J Colloid Interf Sci. 341: 64-68.
Shchukin D.G., Radtchenko I.L. andSukhorukov G.B. (2003). Micron-scalehollow polyelectrolyte capsules withnanosized magnetic Fe3O4 inside.Mater Lett. 57: 1743- 1747.
Spasova M., Salgueirino-Maceira V.n.,Schlachter A., Hilgendorff M., MichaelGiersig, Liz-Marzan L.M., et al. (2005).Magnetic and optical tunablemicrospheres with a magnetite/goldnanoparticle shell. J Mater Chem.15:2095-2098.
485
Wang C., Yan J., Cui X., Cong D. and Wang H.Preparation and characterization ofmagnetic hollow PMMA nanospheresvia in situ emulsion polymerization.Colloid Surface A. in press.
Xi A., Hu J., Wang C. and Jiang D. (2007).Synthesis of magnetic microsphereswith controllable structure viapolymerization-triggered self-positioning of nanocrystals. Small.3(10): 1811-1817.
Xue B., Tong X.D. and Sun Y. (2001).Characterization of PVA-basedmagnetic affinity supported for
protein adsorption. Sep Sci Technol.36: 2449-2461.
Zhang H., Zhang Q., Zhang B. and Guo F.(2009). Preparation of magneticcomposite microspheres by surfactantfree controlled radical poly-merization: Preparation and charac-teristics. J Magn Magn Mater. 321:3921-3925.
Zhang J., Yu D., Chen W., Xie Y., Wan W., LiangH., et al. (2009). Preparation ofpoly(styrene–glucidylmethacrylate)/Fe3O4 composite microspheres withhigh magnetite contents. J MagnMagn Mater. 321: 572-577.
