2003 Enantioselective syntheses

Enantioselective synthesesO 0031 SYNPHOS®, a New Chiral Diphosphine Ligand: Synthesis, Molecular Modeling

and Application in Asymmetric Hydrogenation. — Both enantiomers of the new diphosphine ligand (I) are synthesized and used in ruthenium-mediated hydrogenations of carbonyl substrates. Compared to other diphosphines, (I) affords higher enantiose-lectivities. — (DUPRAT DE PAULE, S.; JEULIN, S.; RATOVELOMANANA-VIDAL, V.; GENET*, J.-P.; CHAMPION, N.; DELLIS, P.; Tetrahedron Lett. 44 (2003) 4, 823-826; Lab. Synth. Sel. Org. Prod. Nat., CNRS, Ec. Natl. Super. Chim., F-75231 Paris, Fr.; Eng.) — Roy

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