SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY, VISHNUPURI ... B.Pharmacy Semester I... · SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY, VISHNUPURI, NANDED ... Syrups: Simple Syrup IP

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SWAMI RAMANAND TEERTH MARATHWADA UNIVERSITY,

VISHNUPURI, NANDED

School of Pharmacy

SYLLABUS

B. PHARM w.e.f.– 2011-2012

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Swami Ramanand Teerth Marathwada University, Nanded

School of Pharmacy B Pharm Course structure (Teaching Scheme)

Wef 2011-12

Semester I Code Title Credits BPY111 Dispensing of Medication (DM) 3 BPY112 Pharmaceutical Inorganic Chemistry (PIC) 3 BPY113 Pharmaceutical Organic Chemistry – I (POC - I) 4 BPY114 Anatomy Physiology & Health Education - I (APHE – I) 4 BPY115 Dispensing of Medication (DM) Lab 3 BPY116 Pharmaceutical Inorganic Chemistry (PIC) Lab 3 BPY117 Pharmaceutical Organic Chemistry – I (POC - I) Lab 3 BPY118 Anatomy Physiology & Health Education -I (APHE –I) Lab 3 BPY119 Remedial Biology (RB) 2 BPY 1110 Remedial Mathematics (RM) 2 Semester II BPY121 Hospital & Community Pharmacy (HCP) 3 BPY122 Pharmaceutical Organic Chemistry – II (POC - II) 4 BPY123 Anatomy Physiology & Health Education – II (APHE– II) 3 BPY124 Pharmacognosy – I (PGY-I) 3 BPY125 Communication Skills (CS) 2 BPY126 Hospital & Community Pharmacy (HCP) Lab 3 BPY127 Pharmaceutical Organic Chemistry – II (POC - II) Lab 3 BPY128 Anatomy Physiology & Health Education – II (APHE– II) Lab 3 BPY129 Pharmacognosy – I (PGY-I) Lab 3 Semester III BPY231 Pharmaceutics I (PH-I) 4 BPY232 Pharmaceutical Organic Chemistry – III (POC - III) 3 BPY233 Pathophysiology of Common Diseases (PCD) 3 BPY234 Pharmacology-I (PCY-I) 3 BPY235 Computer Applications & Biostatistics (CA & B) 1 BPY236 Environmental Studies 2 BPY237 Pharmaceutics I (PH-I) Lab 3 BPY238 Pharmaceutical Organic Chemistry – III (POC - III) Lab 3 BPY239 Pharmacology-I (PCY-I) Lab 3 BPY2310 Computer Applications & Biostatistics (CA & B) Lab 3 Semester IV BPY241 Physical Pharmacy – I (PP–I) 3

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BPY242 Unit Operations in Pharmaceutical Technology (UOPT) 3 BPY243 Biochemistry (Biochem) 4 BPY244 Pharmaceutical analysis-I (PA-I) 3 BPY246 Pharmacology–II (PCY-II) 2 BPY247 Physical Pharmacy– I (PP–I) Lab 3 BPY248 Unit Operations in Pharmaceutical Technology (UOPT) Lab 3 BPY249 Biochemistry (Biochem) Lab 3 BPY2410 Pharmaceutical analysis-I (PA-I) Lab 3 Semester V BPY351 Microbiology & Fermentation Technology (M&FT) 3 BPY352 Physical Pharmacy – II (PP-II) 3 BPY353 Pharmaceutical Analysis – II (PA-II) 3 BPY354 Pharmacognosy – II (PGY-II) 3 BPY355 Immunology & Biotechnology (I&BT) 3 BPY356 Microbiology & Fermentation Technology (M&FT) Lab 3 BPY357 Physical Pharmacy – II (PP-II) Lab 3 BPY358 Pharmaceutical Analysis – II (PA-II) Lab 3 BPY359 Pharmacognosy – II (PGY-II) Lab 3 Semester VI BPY361 Pharmaceutical Technology – I (PT-I) 4 BPY362 Medicinal Chemistry – I (MC-I) 3 BPY363 Pharmacology –III (PCY-III) 3 BPY364 Pharmacognosy – III (PGY-III) 3 BPY365 Pharmaceutical Management (PM) 2 BPY366 Pharmaceutical Technology – I (PT-I) Lab 3 BPY367 Medicinal Chemistry – I (MC-I) Lab 3 BPY368 Pharmacology –III (PCY-III) Lab 3 BPY369 Pharmacognosy – III (PGY-III) Lab 3 Semester VII BPY471 Pharmaceutical Technology – II (PT-II) 4 BPY472 Medicinal Chemistry – II (MC-II) 3 BPY473 Pharmaceutical Analysis –III (PA-III) 3 BPY474 Pharmacology –IV (PCY-IV) 3 BPY476 Pharmaceutical Jurisprudence 3 BPY477 Pharmaceutical Technology – II (PT-II) Lab 3 BPY478 Medicinal Chemistry – II (MC-II) Lab 3 BPY479 Pharmaceutical Analysis –III (PA-III) Lab 3 BPY4710 Pharmacology –IV (PCY-IV)Lab 3 Semester VIII BPY481 Biopharmaceutics & Pharmacokinetics (BP&PK) 4 BPY482 Cosmetic Technology (CT) 2 BPY483 Medicinal Chemistry – III (MC-III) 3

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BPY484 Pharmacotherapy 2 BPY485 Pharmacognosy - IV (PGY-IV) 3 BPY486 Biopharmaceutics & Pharmacokinetics (BP&PK) Lab 3 BPY487 Cosmetic Technology (CT) Lab 3 BPY488 Medicinal Chemistry – III (MC-III) Lab 3 BPY489 Project 1

1 credit = 1 clock hour per week for 12 week

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Scheme of Examination: Semester I Theory Examination Sub code

Subject No. of Papers

Mid term examination Term End Examination Total Marks for subject

Minimum marks for Passing

Duration

(Hr)

Max. Marks Duration (Hr)

Max. Marks

BPY 111

Dispensing of Medication (DM) 1 1 10 02 40 50 20

BPY 112

Pharmaceutical Inorganic Chemistry (PIC)

1 1 10 02 40 50 20

BPY 113

Pharmaceutical Organic Chemistry – I (POC - I)

1 1 10 02 40 50 20

BPY 114

Anatomy Physiology & Health Education - I (APHE – I)

1 1 10 02 40 50 20

BPY119

*Remedial Biology (RB) 1 -- -- 02 50 20 20

BPY 1110

*Remedial Mathematics (RM) 1 -- -- 02 50 20 20

* Home Examination

Note: Candidate must obtain 16 marks at term end examination of each subject in order to declare Pass

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Scheme of Examination: Semester I Lab Course Examination Sub code

Subject No. of Papers

Day to day Evaluation Term End Examination Total Marks for subject

Minimum marks for Passing

Duration

(Hr)

Max. Marks Duration (Hr)

Max. Marks

BPY115

Dispensing of Medication (DM) Lab

1 -- 10 04 40 50 20

BPY116

Pharmaceutical Inorganic Chemistry (PIC) Lab

1 -- 10 04 40 50 20

BPY117

Pharmaceutical Organic Chemistry – I (POC - I) Lab

1 -- 10 04 40 50 20

BPY118

Anatomy Physiology & Health Education -I (APHE –I) Lab

1 -- 10 04 40 50 20

Note: Candidate must obtain 16 marks at term end examination of each subject in order to declare Pass

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F. Y. B. PHARM. Semester I BPY 111

DISPENSING OF MEDICATIONS THEORY

Credits: 03 (03 hr / wk)

1.Evolution of Pharmacy Profession: (07)

Historical background and development of profession of Pharmacy and Pharmaceutical Industry in

India, Definition of Pharmacy, Pharmaceutics. Areas of Pharmaceutics: Physical pharmacy,

Biopharmaceutics, Pharmaceutical Technology, Microbiology, Dispensing and Pharmacy Practices.

Introduction to Pharmacopoeias and other Compendia’s: Indian Pharmacopoeia, British

Pharmacopoeia, United States Pharmacopoeia, International Pharmacopoeia etc., Code of

Pharmaceutical ethics

2. Introduction to Dosage forms: (04)

Classification based on routes of administration and nature, (with definitions), concept of new drug

delivery system- sustained release & targeted drug delivery system with example.

3. Pharmaceutical preparations: (12)

Dispensing procedures for: (Introduction with two examples) Liquids for internal use, Liquids for

external use, Liquids applied to the skin Emulsions, Suspensions, Semisolids, Suppositories, Powders,

tablets, capsules.

4. Alternative systems of medicine: (02)

Introduction to Ayurveda, Homoeopathy, Unani and Siddha.

5. Prescription: (03)

Parts of prescription with functions and importance, possible errors and corrective measures during

prescription handling, prescription pricing & documentation.

6. Pharmaceutical calculations: (04)

Systems of calculation, Alligations, percentage calculations, Isotonic solutions, proof spirit, dilution of

dosage forms.

7. Posology (04)

Meaning, Calculation of dose, factors affecting dose and action of drug, doses of different drugs and

their routes of administration.

Reference Books: 1. Ansel’s Introduction to Pharmaceutical dosage forms & Drug Delivery Systems

2. Cooper & Gunn - Dispensing for Pharmacy students - - 12th edition

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3. Pharmaceutics the Science of dosage form design by M. E. Aulton 2nd Ed. Churchill Livingstone

4. Merk Index

5. Remingtons Pharmaceutical Sciences

6. Harkishin Singh, Pharmacopoeias and Formularies, Vallabh Prakashan, New Delhi

7. M.L Shroff of General Pharmacy Series

8. A Text Book of Pharmaceutical Formulations by B. M. Mithal, 6th Ed., Vallabh

Prakashan, Delhi

9. The Theory & Practice of Industrial Pharmacy by L. Lachman & H. A. Liebermann,

3rd Ed., Varghese Publishing House, New Delhi

10. Modern Dispensing Pharmacy by A. P. Pawar. & R .S. Gaud, 2nd Ed, Career

Publication

11. Indian Pharmacopoeia 2010

12. British Pharmacopoeia 2004

13. British Pharmaceutical Codex

14. United State Pharmacopoeia

15. National Formulary 23 2005

16. Sprowls - Prescription Pharmacy

17. Martindale -The Extra Pharmacopoeia

18. Bradley -- Pharmaceutical calculations

19. Stocklos - Pharmaceutical Calculations

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Dispensing of Medication Lab Course Credits: 03 (03 hr / wk)

Note:

1. Wherever possible Pharmacopoeial products should be prepared. 2. Latest text books and pharmacopoeias should be referred. 3. For all preparations tests will include organoleptic tests and simple tests such as density (wt/ml),

specific gravity, angle of repose, bulk density etc: student are not expected to perform assays and other long time evaluation parameters.

4. Special attention to be paid to the cleanliness and precise working (including documentation) of the candidate in the laboratory.

5. Minimum 12 exercise should be conducted

1. Weighing technique for dispensing: balance sensitivity, Weight box calibration and accuracy, Precision of weighing and error evaluation.

Measuring techniques: Precision and accuracy of measuring and error evaluation Devices for accurate dosage measurement

General Dispensing procedure: Different containers for dispensing, labeling of dispensed medicines

2. Compounding and dispensing with precision of the following preparations:

i. Powders: Oral Rehydration Powder, Dry Syrup Formulation for Reconstitution, Talcum Powder, Tooth Powder, Dusting Powder, Inhalation powder, Effervescent Granules.

ii. Solution : Aqueous Iodine Solution (Lugol) IP, Tincture of Iodine IP, Ferrous sulphate solution, Solution of Cresol With Soap IP , Surgical Chlorinated Soda Solution B.P.C , Paracetamol Pediatric Drops , Magnesium Citrate Solution NF12

iii. Aromatic Waters: Concentrated Dill Water BP, Dill Water, Conc. Anise Water BPC, Chloroform Water, Gripe Water-Modified Aromatic Water,

iv. Liniments: Liniment of Turpentine IP, Liniment of Camphor B.P.C , Soap Liniment

v. Syrups: Simple Syrup IP , Artificial Syrup , Cough Syrup , Dry syrup

vi. Elixirs: Piperazine Citrate Elixir B.P.C, Chloral Hydrate elixir

vii. Linctus: Simple Linctus , Medicated linctus.

viii. Ear And Nose Preparation: Ear Drop Containing Antibiotics (Ex. Gentamycin /Chloramphenicol), Hydrogen peroxide ear drop, Ephedrine Hydrochloride Nasal Drop

ix. Glycerites : Glycerin of Boric Acid I.P , Tannic Acid Glycerin I.P

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x. Suspensions: Milk of magnesia, Paediatric kaolin mixture, Magnesium Trisilicate mixture, Paediatric chalk mixture, Inhalation containing menthol and eucalyptus

xi. Emulsions: Liquid paraffin emulsion, Castor oil emulsion, Arachis oil emulsion

xii. Ointment: Sulphur ointment, Whitfields ointment, Methyl salicylate ointment, Lubricating jelly

xiii. Suppositories: Use of displacement value, Suppository with fatty base, Suppository with PEG base

Reference Books: 1. Ansel’s Introduction to Pharmaceutical dosage forms & Drug Delivery Systems

2. Cooper & Gunn - Dispensing for Pharmacy students - - 12th edition

3. Pharmaceutics the Science of dosage form design by M. E. Aulton 2nd Ed. Churchill Livingstone

4. Merk Index

5. Harkishin Singh, Pharmacopoeias and Formularies, Vallabh Prakashan, New Delhi

6. A Text Book of Pharmaceutical Formulations by B. M. Mithal, 6th Ed., Vallabh Prakashan, Delhi

7. Modern Dispensing Pharmacy by A. P. Pawar. & R .S. Gaud, 2nd Ed, Career Publication

8. Indian Pharmacopoeia 1996

9. British Pharmacopoeia 2004

10. British Pharmaceutical Codex

11. United State Pharmacopoeia

12. National Formulary 23 2005

13. Bradley -- Pharmaceutical calculations

14. Stocklos - Pharmaceutical Calculations

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PHARMACEUTICAL INORGANIC CHEMISTRY THEORY


Objective:

Inorganic chemicals have been used in Pharmacy and Medicine for many reasons ranging from therapeutic to nutritional supplements to Pharmaceutical necessities. The course is designed to study the principles of Inorganic Chemistry to Pharmaceuticals and to study those Inorganic agents used as pharmaceutical aids and necessities or as therapeutic and diagnostic agents.

Introduction to Pharmaceutical Inorganic Chemistry, the significance of the subject (01) Atomic structure: Bohr's model, Wave nature of electrons, Schrodinger's Wave equation, Quantum number, Geometry of Orbitals. (03) Nature of Chemical Bond: (02) Ionic, Covalent, hydrogen, Co-ordinate, valence bond & Molecular orbital theory. Pharmacopoeia : Various Pharmacopoeias, Monograph, I P monograph of Sodium bicarbonate / Boric acid (02) Impurities in pharmaceuticals: (04)

Impurity, types of impurity, sources of impurity & their control, limit test, various limit tests, limit test for chloride, sulphate, lead, Iron, arsenic.

Nuclear Chemistry and Radio pharmaceuticals: (04)

Nuclear Composition, stability of isotope, methods of nuclear radiation, measurement, nuclear reaction, dosimetry, fission and fusion, measurement of radioactivity, modes of dacay, half life period, artificial radioactivity. Radio pharmaceuticals, application of Radiopharmaceuticals in medicines & Pharmacy, Iodine-31, Phosphurus-32,Iron-59. Radiopaque contrast media, Barium sulphate, Quality control of radiopharmaceuticals.

Outline the methods of preparation, Chemistry, chemical properties, mode of action, & uses of the following.

a) Water: (02)

Properties of water, types of water, purification of water, water as the universal pharmaceutical vehicle.

b) Major intra and extra cellular electrolytes ions: (05)

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Extra and intracellular electrolytes & ions such as chloride, bicarbonate, sodium, potassium, calcium, their physiological role, and uses, electrolytes used for replacement therapy, physiological acid base balance, electrolytes used in acid base therapy, electrolyte combination therapy, sodium chloride, potassium chloride.

c) Essential and trace elements: (03)

Essential & non essential elements, iron, copper, Zinc, sulphur and Iodine, their biochemical role, deficiency symptoms and use. Ferrous sulphate, ferrous gluconate, potassium iodide.

d) Gastrointestinal agents: (03)

Definition, Classification, Antacids, Acidifying agents, protective and adsorbents, saline cathartics. Magnesium sulphate, Sodium bicarbonate, Aluminium hydroxide, Bismuth subcarbonate, Kaolin, Hydrochloric acid.

e) Topical agents: (04)

Protective, Antimicrobials & astringents. Talc, Zinc oxide, Hydrogen peroxide, potassium permanganate, Iodine, Sulphur, boric acid, Alum.

f) Dental products : (01)

Anti carries agents, dentifrices, sodium fluride, stannous fluride, pumice, zinc chloride, calcium carbonate.

g) Expectorants, Emetics & Antitussives,: (01)

Ammonium chloride, Potassium iodide.

h) Antidotes: (01)

cyanide poisoning Sodium nitrite, Sodium thiosulphate.

Reference Books:

1. J.H.block, E.B. Roche, T.O. .Soine, C.O. Wilson, Inorganic Medicinal and Pharmaceutical Chemistry, Lea and Febiger, Philadelphia.

2. Bently and Drivers, Text Book of Pharmaceutical Chemistry.

3. Remington's Pharmaceutical Sciences,

4. Pharmacopoeia of India

5. A.H. Beckett & J.B. Stanlake, Practical Pharmaceutical Chemistry, Part I & II

6. J.D. Lee, Concise Inorganic Chemistry, ELBS Publication

7. Alexive V.N., Qualitative Chemical Semimicro Analysis, CBS Publication

8. J.S. Qadry, A Text Book of Inorganic Pharmaceutical and Medicinal Chemistry, B.S. Shah Prakashan.

9. Vogel's Qualitative Inorganic Analysis, Orient Longman

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PHARMACEUTICAL INORGANIC CHEMISTRY LAB COURSE

Credits: 03 (03Hr / wk)

Introduction to Chemistry laboratory (01)

(Study requirement of Inorganic Chemistry Practical, Cleaning and Drying of glassware, various grades of chemicals, care in handling the hazardous chemicals, safety measures, use and care of Balance

Preparation of Inorganic Compounds: (02)

Copper Sulphate, Ferrous Sulphate, Boric acid

Qualitative Analysis of cations and anions (04) Qualitative Analysis of acidic radical and basic radical in a given Inorganic mixture. Semi Quantitative Analysis (03)

Limit test for chloride, sulphate, iron, arsenic on the given sample.

Indian Pharmacopoeia Monographs (02)

Recommended Books: 1) J.H.block, E.B. Roche, T.O. Soine, C.O. Wilson, Inorganic Medicinal and Pharmaceutical

Chemistry, Lea and Febiger, Philadelphia.

2) Bently and Drivers, Text Book of Pharmaceutical Chemistry.

3) Indian Pharmacopoeia.

4) A.H. Beckett & J.B. Stanlake, Practical P’ceutical Chemistry, Part I & II

5) Alexive V.N., Qualitative Chemical Semimicro Analysis, CBS Publication

6) J.S. Qadry, A Text Book of Inorganic Pharmaceutical and Medicinal Chemistry, B.S. Shah Prakashan.

7) Vogel's Qualitative Inorganic Analysis, Orient Longman

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F. Y. B. PHARM.

Semester I BPY 113

PHARMACEUTICAL ORGANIC CHEMISTRY-I Theory


1. Chemical bonding, molecular structure and physical properties. (10)

a. Concepts of structural theory, chemical bond, atomic orbitals, electronic configuration, molecular orbital theory, covalent bond, hybrid orbitals, unshared pairs of electrons, intermolecular forces, bond dissociation energy, polarity of bonds, polarity of molecules, melting point, boiling point, solubility, non-ionic solutes and ionic solutes, protic and aprotic solvents, ion pairs.

b. Acids and bases: Lowry - Bronsted and Lewis theories.

c. Isomerism.

2. Nomenclature of organic compounds belonging to the following classes. (08)

Alkanes, Alkenes, Dienes, Alkynes, Alcohols, Aldehydes, Ketones, Amides, Phenols, Alkyl halides, Carboxylic acids, Esters, Acid chlorides and Cycloalkanes.

3. Introduction to Stereochemistry (12)

Stereoisomerism, Geometric isomerism, Saw-Horse, Fischer’s and Newmann’s projections of molecules, Optical activity, Specific rotation, Enantiomers, Diastereomers, Racemic modifications, Conformational isomerism, Meso-compounds, elements of symmetry, chirality, chiral centres, Nomenclature in stereoisomerism(configurations: R & S, Z & E, D & L), Sequence Rules.

4. Introduction to chemical reaction (10)

Definition, types of organic reactions, substrate, reagent, types of reagent, bond fission, and reaction intermediates, mechanism of organic reactions, factors influencing organic reactions.

5. Free radical chain reactions of alkanes (06)

Mechanism, relative reactivity and their stability.

6. Alicyclic compounds (04)

Preparations of cycloalkanes, Bayer’s strain theory and orbital picture of angle strain.

Reference Books: 1. T.R. Morrison and R. Boyd, Organic chemistry, Prentice Hall of India Pvt. Ltd., New Delhi

2. S.K.Ghosh, Advanced general organic chemistry, New Central Book Agency, Kolkata

3. A. Bahal and B.S. Bahl, A Text Book of organic chemistry, S.Chand & Company Ltd., New Delhi

4. I.L. Finar Organic Chemistry, the fundamentals of chemistry

5. T.W. Graham Solomon’s Fundamentals of Organic Chemistry, John Wiley and Sons Inc. U.S.A.

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6. J.M .Cram and D.J. Cram Organic Chemistry

7. Brown, Organic Chemistry

8. Advanced Organic Chemistry, Jerry and March, Wiley Eastern Limited. New Delhi

9. Organic Chemistry- Crem and Hammered, Pine Hendrickson

10. Organic chemistry – Alinger, Cava, Dejongh

11. Organic Chemistry – Neckers and Doyle

12. Problems and exercises in Organic Chemistry – Agronnonov et al.

13. Organic Chemistry – Streit Weise and Health Cock.

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F. Y. B. PHARM. Semester I

BPY117 PHARMACEUTICAL ORGANIC CHEMISTRY - I

Lab Course Credits: 03 (03 hr / wk)

I. Introduction to organic chemistry laboratory and various laboratory techniques through demonstrations

A. On precautionary measures to be taken while working in organic chemistry laboratory.

B. Involving introduction to various laboratory glasswares, assemblies and equipments.

C. On determination of melting point and boiling point.

D. Involving synthesis of the following compounds (atleast 08 compounds to be synthesized)

1. Acetanilide / Aspirin (Acetylation)

2. Benzanilide / Phenyl benzoate (Benzoylation)

3. Para bromo acetanilide / 2,4,6, - Tribromo aniline (Bromination)

4. Dibenzylidene acetone (Condensation)

5. 1 – Phenyl Azo – 2 – naphthol

6. Benzoic acid / Salicylic acid (Hydrolysis of ester)

7. Meta dinitro benzene (Nitration)

8. 9, 10 – Anthraquinone (Oxidation of anthracene) / Preparation of benzoic acid from toluene or Benzaldehyde.

9. Meta Phenylene Diamine (Reduction of m – dinitro benzene) / aniline from nitro benzene

10. Benzophenone oxime (Oxime formation)

11. Nitration of Salicylic acid

12. Preparation of Picric acid

13. Preparation of o – Chloro benzoic acid from o – chloro toluene

14. Preparation of Cyclohexanone from cyclohexanol

II Introduction to the use of following stereo models.

Methane, Ethane, Ethylene, Acetylene, Cis – alkene, Trans – alkene,

Reference Books:

1. Elementary Practical Organic Chemistry – A.I. Vogel. ELBS and Longman Group Ltd., London

2. Practical Organic Chemistry – Mann and Sounders, ELBS and Longman Group Ltd., London

3. Introduction to Organic Laboratory Techniques – D.L. Pavia., G. Lampman and G.D. Kriz

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F. Y. B. PHARM.

Semester I BPY114

ANATOMY PHYSIOLOGY AND HEALTH EDUCATION-I (APHE – I) THEORY

Credits: 04 (4 HOURS/WEEK)

Objective: The objective of course is to cope with fundamental principles and knowledge of the structure and function of human body. This will helps a student in design and fabrication of drug and delivery system for manipulation in otherwise physiological function of the body.

1. Introduction: Scope of Anatomy and Physiology, basic terminologies used in this subject (Description of the body using planes and terminologies) , Principle systems and their functions, Internal environment and Homeostasis, Communication and reproduction.

03

2. The cell and tissue: Structure and function of cell, cell membrane and cell organelles, Transport of material across cell membrane, Cell cycle. Type of tissue and their subtypes, occurrence and characteristics of tissue and their subtypes, functions.

05

3. Haemopoietic System: Composition and functions of blood and Blood components, Haemopoiesis, Blood groups, Haemostasis-Clotting factors and mechanism.

06

4. Lymph a) Lymph and lymphatic system composition, Formation, and circulation b) Spleen : Physiology and Function

02

5. Cardio vascular system: Anatomy of heart, Blood vessels and circulation, Pulmonary, coronary & systemic circulation, Conduction and ECG, Cardiac cycle and Heart Sounds, Blood Pressure , maintenance and regulation

08

6. Respiratory System: Anatomy of respiratory organs and functions, mechanism and regulation of respiration, Physiology of respiration: Transport of respiratory gases, Respiratory volumes and vital capacity, Neural and chemical regulation of respiration O2 and CO2 carriage and hypoxia, Definitions of Hypoxia, Asphyxia , Dysbarism, Oxygen Therapy and resuscitation

06

7. Nervous System: Neuron, Histology and Physiology, Neuronal Circuits, Definition and classification of nervous system, Functional areas and , functions of cerebrum, Cerebellum, Pons and medulla, Thalamus and Hypothalamus, Basal ganglion, Spinal cord: Structure and functions- reflexes- Mono-Poly-Plantar, Cranial Nerves- Names and functions, CSF –formation and functions, Blood Brain Barrier. ANS-Anatomy and functions of sympathetic and parasympathetic N.S.

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8. Health Education: Definition of Health (Physical & Mental) and Health 06

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Education, Objectives of Health Education, Family Planning, Principles underlying various family planning methods, Nutrition: Definition of nutrition, nutrient, Food – classification – origin, Chemical composition, function and nutritive value, Balanced Diet.

Recommended books:

1) Ross and Wilson. Anatomy and Physiology in health and illness. Churchill Livingstone 2001. 9th edition.

2) Guyton & Hall. Textbook of medical physiology. Elsevier. New Delhi 2000. 10th edition.

3) Vander, Sherman, Luciano. Human Physiology. Mc-Graw Hill Publication New Delhi 1998. 7th edition.

4) Tortora G .J. Principles of anatomy & physiology. Harper Collins College Publishers, New York 1996. 8th edition.

5) Chatterjee C. C. Human Physiology. Medical allied agency. Kolkata 2003. 11th Edition.

6) AB Mc Naught and Callander R. Illustrated Physiology. B.I. Churchill Living

Stone. New Delhi 1987. 1st edition.

7) Chaudhry Sujit K. Consise Medical Physiology. New Cenrtal Book Agency. Calcutta 1993. 2nd edition

8) Douglas E., Kelly, Richard Wood and Allen C. Enders. Bailey`s TextBook of

Microscopic Anatomy. Williams and Wilkins publishers. London 1984. 18th Edition

9) Elaine N. Marieb. Human Anatomy and Physiology. Addison Wesley. New York 1997. 4th edition.

10) Inderbir Singh. Text Book of Human Histology with Colour Atlas. Jaypee

Brothers. New Delhi 2002. 4th edition.

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ANATOMY PHYSIOLOGY AND HEALTH EDUCATION-I Lab Course Credits: 03 (03 hr / wk)

Hematology

1. To study collection of blood sample by pricking and capillary method.

2. Determination of bleeding time

3. Determination of clotting time

4. Determination of blood groups

5. Determination of pulse rate and blood pressure

Study of Microscope

Study of histology using permanent slides

Different histological slides based on chapters covered in theory to be studied

Study of Models

Different models covering, Heart, Respiratory system, Lymphatic system, Nervous System

Study of family planning devices

Like condoms, copper ‘T’, foam tablets, contraceptive pills, etc.

Recommended Books:

1) Kale S. K., R.R. Kale. Practical anatomy physiology and health education. pragati

Prakashan. Pune 1990.

2) Ranade V.G., Pradhan S, Joshi P.N. Text Book of Practical Physiology. Vidyapith

Griha Prakashan. Pune 1997.

3) Mukherjee K. L. Medical Laboratory Technology. Tata McGraw Hill. New Delhi 1999.

4th edition (Vol.I,II,III)

4) Bharihoke V. Text book of Histology .A.I.T.B.S Publication. 2005. 2nd edition

5) Joshi V. D. Practical physiology. Vora publication. Bombay 1998.

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REMEDIAL BIOLOGY THEORY


Course Objective:

The objective of the course is to provide eligibility for the students who did not Biology at 10+2 level.

1. Cell Division: (01)

Introduction- The Cell Cycle - Mitosis - Meiosis - Comparison of Mitosis and Meiosis.

2. Classification: (04)

Introduction- Concept of Species - Various Taxa and Categories - Hierarchial Levels of

Classification - Binomial Nomenclature - Principles of Classification.

3. Conquest of Land: (04)

Introduction - General Account of Pteridophyta (Fems): Nephrolepis-General Account of

Gymnosperms: Cycas - Angiosperms - Dicotyledon, Chinarose - Angiosperms - Monocotyledons -

Jowar / Bajra - Vascularization - Development of seed Habit - Development of Flower and Fruit.

4. Plant Physiology: Photosynthesis: (04)

Introduction- Chloroplasts - Ultra structure and Functions- Overall Equation of Photosynthesis- Primary

Processes of Photosynthesis (Photochemical Phase) - Secondary Processes of Photosynthesis

(Biochemical Phase)- Diversity in - Photosynthetic Pathway - Significance of Photosynthesis.

5. Plant Physiology : Respiration : (03)

Introduction, Ultra structure & functions of mitochondrion - An overvies of cellular Respiration -

Glycolyisis- The TCA Cycle - Electron Transport chain (ETC) - Fermentation - Significance of

Respiration.

6. Sexual Reproduction in Angiosperms: (03)

Introduction - pollination - Structure of male Gametophyte - Structure of Female Gametophyte

- Fertilisation - Formation of Embryo, Endosperm, Seed and Fruit.

7. Domestication of plants: (02)

Introduction – Principles of plant breeding technique of Hybridization –tissue culture.

8. Evolution of Life: (02)

Introduction - Basic Facts and Deductions of the Darwin's Theory - Common Ancestry of All Living

Beings - Differential Reproduction - Speciation - Reproductive Isolation.

9. Human Evolution: (01)

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Introduction and Brief Account of Human Ancestry- Paleontological evidences - Brief Account of

Evolutionary Stages.

10. Sex Determination and Sex Linkage: (02)

Introduction- Sex Determination in Human Being- Sex linkage - Sex linkage in Man with Respect to

Colour-blindness.

REFERENCE BOOK: 1. P.G. Pataskar , Y.B. Mutkekar Biology , Phadke Prakashan, Kolhapur.

2. S.D. Bhagwat , H.D. Sane, A.B. Dandekar, A.D. Marathe & Mrs. C.P. Soman, A text book

of Biology , Narendra Prakashan, Pune.

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Remedial Mathematics THEORY


Course Objective: The objective of the course is to provide eligibility for the students who did not

Mathematics at 10+2 level.

Algebra: Logarithms, Logarithms with particular bases, Arithmetic and geometric progressions,

Permutations and Combinations (04)

Co-ordinate Geometry: Distance Formula, Locus, Equations of straight line in different forms. (04)

Trigonometry: Measurement of angles, Simple relations connecting the complementary and

supplementary angles, standard trigonometric identities. (06)

Calculus:

(a)Differentiation:

Relations and functions (as a pre-requisite), Limit and Continuity, differentiation and its rules,

Differentiation of implicit, trigonometric, composite and parametric functions.

(b)Integration:

Definition, Indefinite integration of some standard functions, definite integrals (11)

Reference Books:

(1) “Calculus and Analytic Geometry”, Thomas and Finney, Pearson Education Limited.

(2) “A Textbook of Mathematics for XI and XII”, NCERT.

(3) “Advanced Engineering Mathematics”, E. Kreyszig, Wiley Eastern Publications

Documents

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