Reactions 1444 - 23 Mar 2013

SSunitinib

Digestive tract haemorrhage in an elderly patient:case report

An 80-year-old woman experienced digestive tracthaemorrhage while receiving sunitinib for recurrentgastrointestinal stromal tumour. The woman started receivingsunitinib 37.5 mg/day [route not stated] in July 2011. Sheexperienced vomiting, nausea, lack of appetite, somnolenceand fatigue [time to onset not stated] and in August 2011 shewas hospitalised after developing haematemesis. She laterpresented with digestive tract haemorrhage, melena andbloody stools. Her haemoglobin level dropped to 76 g/L on6 September 2011. Conservative medical management wasapplied and the haemorrhage stopped; the patient rejectedsuggestions to continue sunitinib.

Author comment: "A digestive tract haemorrhageoccurred as a complication of sunitinib treatment."Liu Y, et al. Digestive tract hemorrhage due to complications with gastrointestinalstromal tumor treated with sunitinib: A case report. Oncology Letters 5: 699-701,No. 2, Feb 2013. Available from: URL: http://dx.doi.org/10.3892/ol.2012.1050 -China 803084844

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Reactions 23 Mar 2013 No. 14440114-9954/10/1444-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved