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JOJO-MA2546-01484
16 November 1872
Dr. A. J. Goudie Johnson & Jolmson Research Center 601 George Street New Brunswick. New Jersey 08901
Dear Dr. Goudie:
Here is our modified thlnklDg on the ba)Jy powder samples lOST and 109T. After looklug at several fresh samples on the light microscope we have not been able to substantiate the tremollte levels we originally reported.
Yours alDcerely.
Ian M. stewart Manager. Electron Optics
Group
ajw Ref: MA 2548 Enclosures
JOJO-MA2546-01485
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JOJO-MA2546-01486
Dr. A . J . Goudie Johnson and Johns on
Research Center 501 George Street
New Brunswick, New Jersey 08901
EXAMINATION
OF
JOHNOON AND JOHNOON'S BABY POWDER
Date: 27 October 1972
MA Number: 2546
Copy of 4
walter c. me crone associates, inc. 2820 SOUTH MICHIGAN A VENUE • CHICAGO, ILLINOIS 60616
JOJO-MA2546-01487
-.
EXAMINATION OF JOHNSON AND JOHNSON'S BABY POWDER
Summary
Two samples of Johnson and Johnson 's Baby Powder, batch number
108T and 109T, which correspond to the samples exam ined by Professor Seymour
Z . Lewin of New York University on behalf of the FDA have been examined by
x-ray diffrac tion, light microscopy , transmission electron microscopy and elec
tron diffraction to determine whether they contain any asbestiform minerals.
Both samples contained an insignificant amount oftremolite -
a few isolated crystals. Neither sample contained chrysotile.
Introduction
On behalf of the FDA, Professor Seymour Z. Lewin of New York
Univer sity is examining a number of commercial talcum powders for the presence
of asbestiform miner al s. Two of the samples which he has examined are samples
of Johnson and J ohnson's Baby Powder, batch number 108T and batch number 109T.
Johnson and Johnson therefore requested Walter C. McCrone Associates to ex
amine samples from the same batches to determine whether they contained any
asbestiform minerals.
Materials and Method of Conducting Tests
Two samples were submitted, identified as Johnson and Johnson's
Baby Powder, batch numbers 108T and 109T.
For x- ray diffrac tion examination, the samples were examined on
a Phillips-Nor elco verticle diffractometer using CuKa radiation and a scanning
speed of 1 o per minute. The dispersion staining teclmique was used for the light
microscopical examination and the el ectron microscopy- electron diffraction ex
amination was carried out us ing procedures previously described (MA report
2330-1 ; dated 10 August 1971).
walter c. me crone associates, inc.
JOJO-MA2546-01488
Results
X-ray Diffraction
The diffractograms were carefully examined in the vicinity of the
major peaks of chrysotile and iTemolite. Neither mineral was present. The
presence of peaks in the vicinity of 12. 0-12-5° 28 , the region in which one of the
principal lines of chrysotile may be found, was correlateq with peaks in the vi
cinity of 6° 28 and are thus attributable to chlorites . No significant peaks were
observed in the 24° region which would be required were chrysotile present.
L ight Microscopy
Using the disper s ion staining technique and a liquid of r efractive
index 1.550, the samples were examined for chrysotile particles and fibers, but
none could be found. Using a similar technique with a liquid of refractive index
1. 605, the samples were similarly examined for the presence of tremolite and a
few individual crystal s were found, some rod shaped.
El ectron Microscopy and Electron Diffraction
Several el ectron microscope gr ids from both samples were ex
amined in their entirety and although some fibers were observed these were shown
by electron diffraction to be shards of talc or rolled talc. No chrysotile fibers
were found.
Conclusion
A detailed examination of two samples of Johnson and Johnson's
Baby Powder, batch numbers 108T and 109T has shown this material to be sub
stantially free of asbestiform minerals. A few tremolite rods were observed in
both samples. No chrysotile has been detected .
Respectfully submitted,
Ian M. Stewart Manager, E lectron Optics Group
walter c . me crone associates, inc.
JOJO-MA2546-01489
Dr. A. J. Goudie Johnson and Johnson
Research Center 501 George Street
New Brunswick, New Jersey 08901
EXAMINATION
OF
JOHNSON AND JOHNSON'S BABY POWDE~
27 October 1972
2546
·4
JOJO-MA2546-01490
EXAMINATION OF JOHNSON AND JOHNSON'S BABY POWDER
Summary
Two samples of Johnson and Johnson's Baby Powder, batch number
lOST and 109T, which correspond to the samples examined by Professor Seymour
Z. Lewin of New York University on behalf of the FDA have been examined by
x-ray diffraction, light microscopy, transmission electron microscopy and elec
tron diffraction to determine whether they contain any asbestifnrm minerals.
Both samples contained an insignificant amount oftremolite ~
a few isolated crystals. Neither sample contained chrysotile ..
Introduction
On behalf of the FDA, Professor Seymour Z. Lewin of New York
University is examining a number of commercial talcum powders for the presence
of asbestiform minerals. Two of the samples which he has examined are samples
of Johnson and Johnson's Baby Powder, batch number lOST and batch number 109T.
Johnson and Johnson therefore requested Walter C. McCrone Associates to ex
amine samples from the same batches to determine whether they contained any
asbestiform minerals.
Materials and Method of Conducting Tests
Two samples were submitted, identified as Johnson and Johnson's
Baby Powder, batch numbers lOST and 109T.
For x-ray diffraction examination, the samples were examined on
a Phlllips-Norelco verticle diffractometer using CuKa radiation and a scanning
speed of 1 o per minute. The dispersion staining technique was used for the light
microscopical examination and the electron microscopy-electron diffraction ex
amination was carried out using procedures previously described (MA report
2330-1; dated 10 August.1971).
JOJO-MA2546-01491
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JOJO-MA2546-01492
Results
.X-ray Diffraction
The diffractograms were carefully examined in the vicinity of the
major peaks of chrysotile and tremolite. Neither ·mineral was present. The
presence of peaks in the vicinity of 12.0-12-5° 28, the region in which one of the
principal lines of chrysotUe may be found, was correlated with peaks in the vi
cinity of 6° 28 and are thus attributable to chlorites. No significant peaks were
observed in the 24 o region which would be required were chrysotUe present.
Light Microscopy
Using the dispersion staining technique and a liquid of refractive
index 1.550, the samples were examined for chrysotile partiqles and fibers, but I
none could be found. Using a similar technique with a liquid of refractive index
1. 605, the samples were similarl¥ examined for the presence of tremolite and a
few individual crystals were fonnd, some rod shaped.
Electron Microscopy and Electron Dif:fr.oaction I
Several electron microscope grids from both samples were ex~
amined in their entirety and although some fibers were observed these were shown
by electron diffraction to be shards of talc or rolled talc. No chrysotile fibers
were found.
Conclusion
A detailed examination of two samples of Johnson and Johnson's
Baby Powder, batch numbers lOST and 109T has shown this material to be sub
stantially free of asbestiform minerals. A few tremolite rods were observed in
both samples. No chrysotile has been detected.
Respectfully submitted,
Ian M. Stewart Manager, Electron Optics Group
JOJO-MA2546-01493
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JOJO-MA2546-01494
JOJO-MA2546-01495
27 October 19'12
Dr. A. J. Goudie Jolmsoa and Jolmson Research Center 601 George Street New Bnmswtck, New Jersey 08901
Dear Dr. Goudie:
Here ls our report on the baby powder samples. I hOpe to bave the Shower to Shower report out to you soon, but so~etblag always seems to break loose whea I sit doWD to wrlte lt.
Yours slllcerely,
laD M. Stewart MaD8pr, Electron Optlcs
Group
aJw Bef: MA 2546 EcDlsoure
JOJO-MA2546-01496
sJbuo~ .• '(, .A · .. ".tG ao~adot hac no~odot
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97-J!Oiilfi:J :'!
JOJO-MA2546-01497
Dr. A. J. Goudie Johnson and Jo1mson
Research Center 501 George St-reet
New Brunswick, New Jersey 08901
EXAMINATION
OF
JOHNSON AND JOHNSON'S BABY POWDER
Date: 27 October 1972
MA Number: 2546
Copy of 4
walter c. me crone associates, inc. 2820 SOUTH MICHIGAN AVENUE • CHICAGO, ILLINOIS 60616
JOJO-MA2546-01498
EXAMINA TTON OF JOHNSON AND JOHNSON'S BABY POWDER
Summary
Two samples of Johnson and Johnson 's Bnby Powder , batch number
l OST and 109T, which correspond to the samples examined by Professor Seymour ! Z. Lewin of New York Univer s ity on behalf of the FDA have been examined by I x -ray diffraction, light microscop~ , transmiss ion electron microscopy and el ec- I ~
tron diffraction to determine whether they contain any asbestiform minerals. ct.n Both samples contained an ins ignificant amount oftr emol ite (~).
1:f;'I:J.
Neither sample contained chrysotile . r
Introduc tion
On behalf of the FDA, Professor Seymour Z. Lewin of New York I University is examining a number of commercial talcum powders for the presence ·
I of asbestiform minerals. Two of the samples which he has examined are samples I of Johnson and Johnson's Baby Powder, batch number lOST and batch number 109T
J ohnson and Johnson therefore r equested Walter C. McCrone Associates to ex- I amine samples from the same batches to determine whether they contained any
asbestiform miner als .
Materials and Method of Conducting Tests
Two samples were submitted, identified as Johnson and Johnson's
Baby Powder, batch numbers lOST and 109'!' .
For x- r ay diffrac tion examination, the samples were examined on
a Phillips - Norclco vert~cle diffractometer us ing CuKa radiation and a scanning
speed of 1° per minute. The dispersion sta ining teclmique was used for the light
microscopical exam ina tion and the electron microscopy- electron diffraction ex
amination wns carried out us ing procedures previously described (MA report
2330-1; dated 10 August 1971).
walter c. me crone associates, inc.
JOJO-MA2546-01499
Resul ts
X-ray Diffroe tion
The diffractogrnm s were carefully examined in the vicinity of the
major peaks of chrys otile and lTcrnolitc. Ne ither m ineral was present. The
presence of peaks in the vicinity of 12. 0-12-G o 28, the r egion in which one of the
principal lines of chrysotile may be found, was correlated with peaks in the vi
cinity of G0 28 and arc thus attributable to chlorites . No sign ificant peaks were
obser ved in the 24° region which would be required were chrysotile present .
Light Micr oscopy
Using the d ispersion sta ining technique and a liquid of refractive
index 1. 550 , the samples were exam ined for chrysotile particles and f ibers, but
none c'ould be found. Using a sim ilar technique with a liquid of refractive index
1. 605, the samples were s imilarly examined for the presence of tremolite and a
few ind iv idual crystal s were found, some r od shaped . ...:che tetal h emolite ceRteHt
,~ the f:o:w samples 'Nel:lld be appr ox ima tcly 0 . 5% for 1M 'f ani1 about o. ~-6 . s %-
f.oP 199T.
Electr on Microscopy and Electron Diffraction
Several el ectron microscope gTids from both samples were ex
a mined in the ir entirety and although some fib er s were observed these were shown I by el ectron diffraction to be shards of talc or rolled talc. No chrysotile fibers
wer e found .
Conclusion
A detailed examination of two samples of J ohnson and Johnson's
Baby Powder, batch numbers 108T and 109T has shown this material to be sub
stantially fr ee of asbestiform mineral s . A few tTcmolite r ods were observed in
both samples. at a levgJ less the:R Q. ~ ){, . No chrysotilc has been detected .
Respectfully subm iitcd,
I (L o"o / / . _:.:'/ • • • C< .. - : •
Ian 1\1. Sl·cwar t l\Tanagcr, ElcctTon Optic s Group
-2- wa lter c. me crone associatGs, inc.
