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A multicentre assessment of NSAIDs as risk factors for post-operative adverse events Student Audit and Research in Surgery

STARSurgUK @ National Research Collaborative Meeting 2013

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Page 1: STARSurgUK @ National Research Collaborative Meeting 2013

A multicentre assessment of NSAIDs as risk factors for

post-operative adverse events

Student Audit and Research in Surgery

Page 2: STARSurgUK @ National Research Collaborative Meeting 2013

Why?

Page 3: STARSurgUK @ National Research Collaborative Meeting 2013

Steering Committee• Mr Chetan Khatri

• Mr Michael Kelly

• Mr Stephen Chapman

• Mr James Glasbey

• Dr Dmitri Nepogodiev

• Mr Edward Fitzgerald

• Mr Aneel Bhangu

Page 4: STARSurgUK @ National Research Collaborative Meeting 2013

Collaborator Locations

Page 5: STARSurgUK @ National Research Collaborative Meeting 2013

NSAIDS

• Used regularly as post-operative analgesics as part of ERAS, WHO pain ladder.

• Increasing evidence1,2 emerging that NSAIDs may have a detrimental effect on post-operative adverse events

1Gotissen, BJS, 2012, 2Klein, BMJ, 2012

Page 6: STARSurgUK @ National Research Collaborative Meeting 2013

Aims

• To audit the safety profile of post-operative NSAIDs in current British surgical practice

• To form a student network with the capacity of undertaking clinical audit and research

Page 7: STARSurgUK @ National Research Collaborative Meeting 2013

Methods

• Identification of consecutive patients undergoing bowel resection over 14 day period

• Possible data collection from Tuesday 24th September - Monday 21st October 2013

• +30 day follow-up period

Page 8: STARSurgUK @ National Research Collaborative Meeting 2013

Audit vs. Research

Page 9: STARSurgUK @ National Research Collaborative Meeting 2013

Audit vs. Research

• HRA Tool

• NRES Committee

• NREC Chair Approval

Page 10: STARSurgUK @ National Research Collaborative Meeting 2013

DATA QUALITY

Page 11: STARSurgUK @ National Research Collaborative Meeting 2013

Data Quality

• Online e-module designed to teach Clavein-Dindo Classification

• 279 completed the quiz

Page 12: STARSurgUK @ National Research Collaborative Meeting 2013

Data Quality

Doctor compulsory member of every mini-team (one per team of three)

Page 13: STARSurgUK @ National Research Collaborative Meeting 2013

Results

• 72 centres returned data

• n=956

• Awaiting final data sets before analysis

Page 14: STARSurgUK @ National Research Collaborative Meeting 2013

Thank you