Sociedad Hondurea de Epilepsia Captulo de la ILAE Dra. Claudia
Amador Dr Marco Tulio Medina Dra. Sofia Dubon The Flag of Honduras
Slide 2 Honduran Epilepsy Society 1. Dr. Claudia Amador * President
2. Dr. Heike Hesse Vice President 3. Prof. Marco T. Medina Past
President 4. Dr. Reyna Duron Secretariat 5. Dr. Lazaro Molina
Treasurer Slide 3 HONDURAS Is a Central America Country with a
Population of 8 millions Slide 4 Health Care Three Health Systems
in Honduras: 1.Ministry of Health 2.Social Security for state
workers and others 3.Private Hospitals Slide 5 Neurological Care
There was one neurologist per 325,000 inhabitants in 1998
Neurological diseases account for approx. 20% of the medical
consultations in hospitals Slide 6 Formacin de Neurlogos y
Epileptlogos WFN Slide 7 Epidemiologa (Medina et al Epilepsia 2003,
2005) Slide 8 TREATMENT Slide 9 Status Epilepticus Slide 10
Proyecto Demostrativo en Honduras: Brecha de Tratamiento Slide 11
Community Intervention (Medina et al 2010, submitted) Slide 12
Significant reduction of Epilepsy due to NCC (36% versus 13.9%)
Slide 13 Neuroepidemiology Studies Slide 14 Slide 15 Slide 16 The
Salama Epilepsy Study ETIOLOGY OF EPILEPSY (n=90)
Neurocysticercosis 37% Cryptogenic (occult) 30% Idiopathic 8%
Perinatal brain damage 8 % Head trauma 3% CNS malformations 2%
Vascular 2% Other neuroinfections 2% Other causes* 8% Other causes:
inespecific calcified lesions, alcohol toxicity, inespectific
intraventricular cyst, multifactorial. Slide 17 Government
involvement Slide 18 Slide 19 Epilepsy Surgery Program in Honduras
Slide 20 DiseaseJMECAE Phenotype Myoclonic, grand mal epilepsy, 1/3
with absences Pyknoleptic (2-200/day) absences of childhood
PathologyMicrodysgenesis-Displaced and dystopic cells Normal
GeneMyoclonin/ EFHC1 GABRB3 Transgenic mice KO mice replicate
pathology and susceptibility KO mice replicate epilepsy Epilepsy
Genes Epilepsy genes found in Honduras Slide 21 Suzuki et al.Nature
Genetics, 2004 Slide 22 Tanaka M, Olsen RW, Medina MT, et al Am J
Hum Genet. 2008 Jun;82(6):1249-61. Slide 23 Medina MT et al.
Neurology 2008 Slide 24 Group of Patients Epilepsy (FUNDACION
HONDURENA DE EPILEPSIA) Slide 25 Publicaciones (Books and Journals
Slide 26 Latin American Epilepsy Academy (Academia Latino Americana
de Epilepsia ALADE) Founded in Sao Paulo Feb. 27th, 2007
