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Sleep-Wake Disorderspage 390-422 starts w/ Circadian Rhythm Sleep-Wake Disorder
❖ All info is either from DSM-5 (diagnostic/assessment) or our Text (treatments)
❖ -for the unspecified/specified
❖ I consulted the stated disorder (ie insomnia for “Other Specified Insomnia Disorder”) However I did not research this section, so it would be good to take a look at the assessment and treatment of the stated disorder, and compare
❖ It seems like those are quite up in the air depending on symptoms presented
Sleep Wake DisordersBreathing Related Sleep Disorders
Disorder Codes Subtypes Assessment Treatment
Circadian Rhythm Sleep-WakeDisordersCode: 307.45(DSM-5 pp. 391-8)
❖ Delayed sleep phase type G47.21
❖ Advanced sleep phase type G47.22
❖ Irregular Sleep-Waketype G47.23
❖ Non-24-hour sleep-wake type G47.24
❖ Shift Work type G47.26❖ Unspecified type G47.20
❖ Sleep Diary❖ Actigraphy (wrist-
sleep/wake detector)❖ Diagnosis Unclear-
Biomarkers (Salivary dim light melatonin onset)
❖ Sequential Measurement of phase markers (melatonin) (primarily for Non-24 hour sleep-wake type)
❖ Sleep log associated with chronobiology (resetting daily life schedule)
❖ Behavior modification Techniques
❖ Interventions: psychoeducation, light therapy (increasing melatonin), restrictions on alcohol/caffeine, sleep hygiene rules
(Kress & Paylo, 2015, p. 504)
Sleep Wake DisordersParasomnias
Disorder Codes Assessment Treatment
Non-Rapid Eye Movement Sleep Arousal Disorders
❖ Sleepwalking type 307.46 (F51.3)
❖ Sleep Terror type 307.6 (F51.4)
❖ Polysomnography and audiovisual monitoring to document episodes
❖ Children-family therapy, increased emotionalconnection
❖ Adults Interventions: reduce deep sleep through medication, behavior changes, counseling to consider options
Nightmare Disorder ❖ 307.47 (F51.5) ❖ Polysomnography ❖ Cognitive Behavioral TherapyInterventionsImage Rehearsal Therapy, Lucid dreaming therapy, Exposure, Relaxation and RescriptingTherapy (EERT)
Rapid Eye Movement Sleep Behavior Disorder
❖ 327.42 (G47.52) ❖ Medical evaluationPolysomnography
❖ Medications (melatonin, clonazepam)
Restless Legs Syndrome
❖ 333.94 (G25.81) ❖ Self-Report, History of episodes, Immobilization Test, serum ferritin level test (iron in body), Polysomnography
❖ For mild case: Self-directed activities during onset of sensation (read, stretch, massage)
❖ For Severe case: medication (low-dose dopamine agonists)
Last resort: Anticonvulsants, Opiods
(Kress & Paylo, 2015, pp. 505-6)
Sleep Wake DisordersParasomnias (continued)
Disorder Assessment Treatment
Substance/Medication-Induced Sleep Disorder
❖ Medical evaluation/ consultation, Electroencephalographic sleep profile,All night Polysomnography, Multiple Sleep Latency Test, 2 Week Sleep Diary, Actigraphy, Drug Screening
❖ Consult with medical doctor, psychiatrist
❖ Cognitive Behavioral Therapy, Behavioral therapy
❖ Psychoeducation, sleep hygiene rules, relaxation techniques, sleep restrictions, cognitive techniques
Other Specified Insomnia Disorder
❖ Polysomnography, Quantitative electroencephalographic analysis
❖ Cognitive Behavioral Therapy, Behavioral therapy
❖ Psychoeducation, sleep hygiene rules, relaxation techniques, sleep restrictions, cognitive techniques
Unspecified InsomniaDisorder
❖ Polysomnography, Quantitative electroencephalographic analysis
❖ Cognitive Behavioral Therapy, Behavioral therapy
❖ Psychoeducation, sleep hygiene rules, relaxation techniques, sleep restrictions, cognitive techniques
Other Specified Hypersomnolence Disorder
❖ Medical evaluation/ consultation, Multiple sleep latency test, Nocturnal polysomnography
❖ Cognitive Behavioral Therapy, Behavior therapy, psychopharmacotherapy
Sleep Wake DisordersParasomnias (continued)
Disorder Assessment Treatment
Unspecified Hypersomnolence Disorder
❖ Medical evaluation/ consultation, Multiple sleep latency test, Nocturnal polysomnography
❖ Cognitive Behavioral Therapy, Behavior therapy,
psychopharmacotherapy
Other Specified Sleep-Wake Disorder
❖ Medical evaluation/ consultation, Biological validators, Polysomography
Treatment Depends on presenting symptoms❖ Cognitive Behavioral Therapy,
Behavioral therapy, medications, oral applications, ventilators
❖ Psychoeducation, sleep hygiene rules, relaxation techniques, sleep restrictions, cognitive techniques
Unspecified Sleep-Wake Disorder
❖ Medical evaluation/ consultation, Biological validators, Polysomography
Treatment Depends on presenting symptoms❖ Cognitive Behavioral Therapy,
Behavioral therapy, medications, oral applications, ventilators
❖ Psychoeducation, sleep hygiene rules, relaxation techniques, sleep restrictions, cognitive techniques
(Kress & Paylo, 2015, pp. 361-73)
Sleep-Wake Disorders: Diagnostic Criteria: Circadian Rhythm Sleep-Wake Disorders
Circadian
Rhythm Sleep-
Wake Disorders (DSM-5 pp.391-8)
1. Delayed Sleep
Phase Type
Code: 307.45 (G47.21)
2. Advanced Sleep
Phase Type
Code: 307.45 (G47.22)
3. Irregular Sleep-
Wake Type
Code: 307.45 (G47.23)
4. Non-24 Hour
Sleep-Wake Type
Code: 307.45 (G47.24)
5. Shift Work
Type
Code: 307.45
(G47.26)
❖ Recurrent Pattern
of Sleep disruption
❖ Excessive
sleepiness,
insomnia, or both
❖ Causes distress or
impairment in
social
occupational, &
other functioning
+ History of delay in timing of
major sleep pd.(usually 2+ hrs.)
compared to desired sleep/wake
+ Lasts 3+ months
time
+Difficulty waking in the
morning (morning confusion)
+Excessive early day sleepiness
Common features
+history of mental
disorder/concurrent mental
disorder
+Psychophysiological insomnia
Differential Diagnosis:
Normative variations in Sleep
Other Sleep Disorders
+Sleep-wake times several hours
earlier than desired
+History of advance in timing of
major sleep pd. (usually 2+ hrs.)
compared to desired sleep/wake
time
+Early morning insomnia
+Excessive daytime sleepiness
+”morning types” biomarkers
occur 2-4 hr. earlier than normal
+use of drugs to combat sleep-
wake time may lead to substance
abuse
+Onset late adulthood
+Familial
+Symptom severity increases
with age
+varies according to lifestyle and
lifespan
Differential Diagnosis:
Other Sleep Disorders
Depressive and Bipolar
Disorders
+history of insomnia at night
+excessive sleepiness/napping
in the day
+No major sleep pd.
+Fragmented sleep into at
least 3 pds. in 24 hrs.
+Commonly linked to
neurodegenerative disorders
(major neurocognitive
disorder, neurodevelopmental
disorders)
+Linked to limited
environmental light exposure
Differential Diagnosis:
Normative variations in sleep
Other medical conditions and
mental disorders
+Pattern of sleep-wake cycles
not synchronized to 24 hr.
environment
+Consistent daily drift of
sleep-wake times.
+pds of insomnia, excessive
sleepiness or both altering
with asymptomatic pds.
+Common among the visually
impaired (50% prevalence)
+In sighted individuals often
due to lack of light and
structured activity
+Associated with traumatic
brain injury
Differential Diagnosis:
Circadian Rhythm Sleep-Wake
Disorders
Depressive Disorders
+based on history of
individual working out
of 8AM-6PM daylight
schedule on a regular
basis
+Insomnia during major
sleep pd.
and/ or
+Excessive sleepiness
during major awake pd.
associated with a shift
work schedule
+May effect travelers
frequently flying across
time zones
+May effect those with
rotating shifts
+Common in 50+
Differential Diagnosis:
Normative Variations in
Sleep with Shift Work
R/O:
Other Sleep Disorders
Sleep-Wake Disorders: Diagnostic Criteria: Parasomnias
Parasomnias
(DSM-5 pp. 399-
422)
Non-Rapid Eye
Movement (NREM)
Sleep Arousal
Disorders
Sleepwalking type Code:
307.46(F51.3)
Sleep terror type
Code: 307.46 (F51.4)
Non-Rapid Eye
Movement (NREM)
Sleep Arousal
Disorders
(Continued)
Non-Rapid Eye
Movement
(NREM)
Sleep Arousal
Disorders
(Continued)
Nightmare
Disorder
Code: 307.47
(F51.5)
Rapid Eye
Movement (REM)
Sleep Behavior
Disorder
Code: 327.42
(G47.52)
Restless Leg
Syndrome
Code: 333.94
(G25.81)
❖ Abnormal
behavioral,
experiential or
physiological
events
occurring w/
sleep/specific
sleep
stages/sleep-
wake
transitions
❖ Most common
NREM Sleep
Behavior Disorder
REM Sleep
Behavior Disorder
+Repeated occurrence of
incomplete arousals can be brief
up to 10 mins. or up to 1 hr. in
first 3rd of sleeping episode
+eyes are typically open
Sleepwalking
+repeated episodes of complex
motor behavior initiated during
sleep
+Episodes begin during NREM
+reduced alertness
+blank stare
+unresponsive to
communication
+limited recall afterward
+initial confusion immediately
following
+return to full cognitive
function afterwards
Sleep Terrors
+Repeated occurrence of sudden
awakening from sleep
+Often begins w/ scream/cry
+Automatic arousal
+Intense fear, compulsion to
escape
+Automatic arousal (rapid
breathing, sweating, etc.)
+Unresponsiveness to others
efforts to comfort
+No or little dream imagery
(single scene)
+Amnesia for episode
+Significant stress and
impairment of functioning
+Not due to drug use/
Medication
+Mental and Medical disorders
do not explain episodes
Sleep Related Eating Disorder
+eating w/ amnesia ranging
from no-full awareness
Sleep Related sexual behavior
(sexsomnia)
+Arising from sleep and
participating in sexual activity
w/ no conscious awareness
Common in children
+link w/ major depressive
episodes and obsessive-
compulsive disorder
Differential Diagnosis:
Nightmare Disorder
Breathing-Related Sleep
Disorders
REM Sleep Behavior
Disorder
Parasomnia Overlap
Syndrome
Sleep-Related Seizures
Alcohol-Induced
Blackouts
Dissociative Amnesia, w/
Dissociative Fugue
Malingering or other
voluntary behavior
occuring during
wakefulness
Medication-Induced
Complex Behaviors
Night Eating Syndrome
+Repeated occurrences of
dream imagery involving
extreme negative emotions
+well remembered
+Alert after dream episode
+Significant distress or
impairment in functioning
Replicative Nightmares
-occur after a traumatic
experience
Differential Diagnosis:
Sleep Terror Disorder
REM Sleep behavior
Disorder
Bereavement
Narcolepsy
Nocturnal Seizures
Breathing-Related Sleep
Disorders
Panic Disorder
Sleep-Related Dissociative
Disorders
Medication or Substance
Abuse
+Repeated episodes of
arousal during sleep
+Vocal and/or complex
motor behaviors in
response to threats “dream
enacting behaviors”
+Motor behaviors can be
violent
+Happen in REM sleep
(90 mins into sleep onset)
+Awaken alert and NOT
confused/disoriented
+Causes significant
distress and/or impairment
of functioning
+Present in 30% of
narcoleptics
Differential Diagnosis:
Other Parasomnias
Nocturnal Seizures
Obstructive Sleep Apnea
Other Specified
Dissociative Disorder
Malingering
+desire to move the legs or
arms due to uncomfortable
feelings
+Urge to move
-worsens during rest
-is relieved by
movement
-worse in evening
+3x/week
+At least 3 months
+Causes significant
distress and/or impairment
of functioning
Differential Diagnosis:
Substance Intoxication or
withdrawal
Delirium
Other Sleep Disorders
Sleep Disorder due to
another medical condition
Sleep-Wake Disorders: Diagnostic Criteria: Parasomnias
Substance/
Medication-
Induced Sleep
Disorder
(DSM-5 pp 417-8)Code: 780.52 (G47.00)
1.Alcohol
(291.82)
2.Caffeine
(292.85)
3.Cannabis
(292.85)
4. Opiods
(292.85)
5. Sedative,
hypnotic, or
anxiolytic
(292.85)
6.Amphetamine
(or other
stimulant)
(292.85)
7. Tobacco
(292.85)
8. Other (or
unknown)
Substance
(292.5)
Prominent/severe
disturbance in sleep
-develop during/after
intoxication or
-after withdrawal
and
-Substance is capable of
sleep disturbance
+Sleep disorders are ruled
out
+does not occur during
delirium
+Symptoms cause
significant distress
or
Impairment of functioning
Differential Diagnosis:
Substance intoxication or
withdrawal
Delirium
Other Sleep Disorders
Sleep Disorder due to
another medical condition
+often occurs
with insomnia
type
+Extremely
disrupted sleep
First half of night
+Immediate/
short lived
sedative effect
+increased
intensity of REM
sleep (vivid
dreams- alcohol
withdrawal
delirium)
Second half of
night
+Restlessness
+can aggravate
breathing-related
sleep disorder
+fragmented
sleep can last for
weeks/years in
chronic alcohol
users
+produces
insomnia
+signs of
withdrawal =
daytime
sleepiness
+may shorten
sleep latency
+enhances slow
wave sleep /sleep
inducing
+Chronic users
develop
tolerance to sleep
effects
+ Withdrawal
signs sleep
difficulties and
unpleasant
dreams
-may last for
weeks
-Increase in
sleepiness and
sleep depth
-W/ chronic use
tolerance
develops and
insomnia
-Respiratory
depressant effects
worsen sleep
apnea
+Similar to
Opiods
+Increases
sleepiness
+Decreases
wakefulness
+W/ chronic use
tolerance develops
and insomnia
+Daytime
sleepiness
+Insomnia during
intoxication
+Excessive
Sleepiness during
withdrawal
+MDMA
-restlessness and
disturbed sleep
within 48
hrs.
-frequent use is
connected with
anxiety, depression,
steep disturbances
even during pds. of
non use
+Insomnia
+Decreased slow-
wave sleep
+Reduction of
sleep efficiency
+Increased
daytime
sleepiness
+Withdrawal
-impaired sleep
+Heavy smokers
may awake at
night due to
cravings
+Medications
affecting
central. and/or
automatic
nervous
systems may
cause sleep
disturbances
Sleep-Wake Disorders: Diagnostic Criteria: Parasomnias
Other Specified
Insomnia Disorder
Code: 780.52(G47.09)
Unspecified
Insomnia Disorder
Code: 780.52 (G47.00)
Other Specified
Hypersomnolence
Disorder
Code: 780.54 (G47.19)
Unspecified
Hypersomnolence
Disorder
Code: 780.54 (G47.10)
Other Specified
Sleep-Wake
Disorder
Code: 780.59 (G47.8)
Unspecified Sleep-
Wake Disorder
Code: 780.59 (G47.9)
+Does not meet full
diagnostic criteria for
Insomnia/sleep-wake
disorders
+Used when clinician
CHOOSES TO SPECIFY
reason why criteria is not
met for insomnia/sleep-wake
disorders
+insomnia disorder
symptoms cause significant
distress
or
Impair areas of functioning
+Brief Insomnia Disorder
-pd. less than 3 mos.
+Restricted to nonrestorative
sleep
+Does not meet full
diagnostic criteria for
Insomnia/sleep-wake
disorders
+Used when a clinician
CHOOSES NOT TO
SPECIFY a reason criteria
are not met for
insomnia/sleep-wake
disorders
+insomnia disorder
symptoms cause significant
distress
or
Impair areas of functioning
+Insufficient information to
make a more specific
diagnosis
+Does not meet full
diagnostic criteria for
Hypersomnolence/sleep-
wake disorders
+Used when clinician
CHOOSES TO SPECIFY
reason why criteria is not
met for hypersomnolence/
sleep-wake disorders
+Hypersomnolence disorder
symptoms cause significant
distress
or
Impairment of functioning
(e.g., brief-duration
hypersomnolence)
+Does not meet full
diagnostic criteria for
Hypersomnolence/sleep-
wake disorders
+Used when a clinician
CHOOSES NOT TO
SPECIFY a reason criteria
are not met for
hypersomnolence/sleep-
wake disorders
+Hypersomnolence disorder
symptoms cause significant
distress
or
Impairment of functioning
+Insufficient information to
make a more specific
diagnosis
+Does not meet full
diagnostic criteria for sleep-
wake/other specified
insomnia/ other specified
hypersomnolence disorders
+Used when clinician
CHOOSES TO SPECIFY
reason why criteria is not
met for sleep-wake/other
specified insomnia/ other
specified hypersomnolence
disorders
+Sleep-Wake Disorder
symptoms cause significant
distress
or
Impairment of functioning
+Does not meet full
diagnostic criteria for sleep-
wake/other specified
insomnia/ other specified
hypersomnolence disorders
+Used when a clinician
CHOOSES NOT TO
SPECIFY a reason criteria
are not met for sleep-
wake/other specified
insomnia/ other specified
hypersomnolence disorders
+Sleep-Wake Disorder
symptoms cause significant
distress
or
Impairment of functioning
+Insufficient information to
make a more specific
diagnosis
Diagnosis Assessment Treatment
Diagnostic Criteria
• A predominant compliant of dissatisfaction with sleep
quantity/quality, along with at least one of the following:
1. Difficulty initiating sleep (In children, may be without caregiver
intervention)
2. Difficulty maintaining sleep due to frequent awakenings or
problems returning to sleep after reawakenings (In children, may
be difficulty returning to sleep without caregiver intervention)
3. Early-morning reawakening with inability to return to sleep
• Causes clinically significant distress or impairment in functioning
• The sleep difficulty occurs at least 3 nights per week
• Is present for at least 3 months
• Occurs despite adequate opportunity for sleep
• Specify if:
With non-sleep disorder mental comorbidity, including
substance use disorders
With other medical comorbidity
With other sleep disorder
• Specify if:
Episodic: Symptoms last at least a month but less than 3
months
Persistent: Symptoms last 3 months or longer
Recurrent: Two (or more) episodes within the space of a year
Differential Diagnosis
• Normal sleep variations
• Situational/acute insomnia
• Delayed sleep phase and shift work types of circadian rhythm
sleep-wake disorder
• Restless legs syndrome
• Breathing-related sleep disorders
• Narcolepsy
• Parasomnias
• Substance/medication-induced sleep disorder, insomnia type
• Traditional clinical
interview (Kress &
Paylo, 2015)
• Referral to a sleep
disorder center or to a
sleep disorder specialist
for use of laboratory
examinations (Kress &
Paylo, 2015)
• CBT
• Behavior Therapy
(BT)
Psychopharmacotherapy
• Sedative-hypnotics
• Benozodiazepines
Sleep-Wake Disorders
•Insomnia Disorder (DSM Pages 362-368)
Diagnosis Assessment Treatment
Diagnostic Criteria
• Self-reported excessive sleepiness despite a main sleep period
lasting at least 7 hours, with at least one of the following:
1. Recurrent periods of sleep or lapses into sleep within the same day
2. A prolonged main sleep episode of more than 9 hours per day that
is nonrestorative
3. Difficulty being fully awake after abrupt awakening
• Occurs at least 3 times per week for at least 3 months
• Accompanied by significant distress or impairment in functioning
• Specify if:
With non-sleep disorder mental comorbidity, including
substance use disorders
With medical condition
With other sleep disorder
• Specify if:
Acute: Duration of less than 1 month
Subacute: Duration of 1-3 months
Persistent: Duration of more than 3 months
• Specify current severity:
Mild: Difficulty maintaining daytime alertness 1-2days/week
Moderate: Difficulty maintaining daytime alertness 3-4
days/week
Severe: Difficulty maintaining daytime alertness 5-7 days/week
Differential Diagnosis
• Normative variation in sleep
• Poor sleep quality and fatigue
• Breathing-related sleep disorders
• Circadian rhythm sleep-wake disorders
• Parasomnias
• Other mental disorders
• Traditional clinical
interview (Kress &
Paylo, 2015)
• Referral to a sleep
disorder center or to a
sleep disorder specialist
for use of laboratory
examinations (Kress &
Paylo, 2015)
• Medical evaluation and
consultation (Kress &
Paylo, 2015)
• BT
Psychopharmacotherapy
• Stimulants
(Amphetamines)
(Mazindol, Modafinil)
• Antidepressants
•Hypersomnolence Disorder (DSM Pages 368-372)
Diagnosis Assessment Treatment
Diagnostic Criteria
• Recurrent periods of an irrepressible need to sleep, lapsing into sleep, or napping occurring with the same day; occurring at least 3 times per week over the past 3 months
• Presence of at least one of the following:
1. Episodes of cataplexy, defined as either (a) or (b), occurring at least a few times per month:
a. In individuals with long-standing disease, brief (seconds to minutes) episodes of sudden bilateral loss of muscle tone with maintained consciousness that are
precipitated by laughter or joking
b. In children or in individuals within 6 months of onset, spontaneous grimaces or jaw-opening episodes with tongue thrusting or a global hypotonia, without any
obvious emotional triggers
1. Hypocretin deficiency, as measured using cerebrospinal fluid (CSF) hypocretin-1 immunoreactivity values (less than or equal to one-third of values obtained in healthy subjects tested
using the same assay, or les than or equal to 110 pg/mL) not observed in the context of acute brain injury, inflammation, or infection
2. Nocturnal sleep polysomnography showing rapid eye movement (REM) sleep latency less than or equal to 15 minutes, or a multiple sleep latency test showing a mean sleep latency less
than or equal to 8 minutes and tow or more sleep-onset REM periods
• Specify whether:
347.00 Narcolepsy without cataplexy but with hypocretin deficiency: Criterion B requirements of low CSF hypocretin-1 levels and positive polysomnography/multiple sleep latency
test are met, but no cataplexy is present (Criterion B1 not met)
347.01 Narcolepsy with cataplexy but without hypocretin deficiency: In this rare subtype (less than 5 % of narcolepsy cases), Criterion B requirements of cataplexy and positive
polysomnography/multiple sleep latency test are met, but CSF hypocretin-1 levels are normal (Criterion B2 not met)
347.00 Autosomal dominant cerebellar ataxia, deafness, and narcolepsy: This subtype is caused by exon 21 DNA (cystosine-5)-methyltransferase-1 mutations and is characterized by
late-onset (age30-40 years) narcolepsy (with low or intermediate CSF hypocretin-1 levels), deafness, cerebellar ataxia, and eventually dementia
347.00 Autosomal dominant narcolepsy, obesity, and type 2 diabetes: Narcolepsy, obesity, and type 2 diabetes and low CSF hypcretin-1 levels have been described in rare cases and
are associated with a mutation in the myelin oligodendrocyte glycoprotein gene
347.10 Narcolepsy secondary to another medical condition: This subtype is for narcolepsy that develops secondary to medical conditions that cause infectious (e.g., Whipple’s
disease, sarcoidosis), traumatic, or tumoral destruction of hypocretin nuerons
• Specify current severity:
Mild: Infrequent cataplexy (less than once per week), need for naps only once or twice per day, and less disturbed nocturnal sleep
Moderate: Cataplexy at least once daily or every few days, disturbed nocturnal sleep, and need for multiple naps daily
Severe: Drug-resistant cataplexy with multiple attacks daily, nearly constant sleepiness, and disturbed nocturnal sleep
Differential Diagnosis
• Other hypersomnias
• Sleep deprivation and insufficient nocturnal sleep
• Sleep apnea syndromes
• Major depressive disorder
• Conversion disorder
• ADHD or other behavioral problems
• Seizures
• Chorea and movement disorders
• Schizophrenia
• Traditional clinical interview (Kress & Paylo, 2015)
• Referral to a sleep disorder center or to a sleep disorder
specialist for use of laboratory examinations (Kress & Paylo,
2015)
• Medical evaluation and consultation (Kress & Paylo, 2015)
• BT
Psychopharmacotherapy
• Stimulants (Amphetamines)
(Mazindol, Modafinil)
• Antidepressants
Narcolepsy (DSM Pages 372-378)
Diagnosis Assessment Treatment
Diagnostic Criteria
• Either (1) or (2):
1. Evidence of polysomnography of at least 5 obstructive apneas or
hypopneas per hour of sleep and either of the following sleep
symptoms:
a. Nocturnal breathing disturbances: snoring, snortin/gasping, or
breathing pauses during sleep
b. Daytime sleepiness, fatigue, or unrefreshing sleep despite
sufficient opportunities to sleep that is not better explained by
another mental disorder and is not attributable to another medical
condition
1. Evidence by polysomnography of 15 or more obstructive apneas
and/or hypopneas per hour of sleep regardless of accompanying
symptoms
• Specify current severity:
Mild: Apnea hypopnea index is less than 15
Moderate: Apnea hypopnea index is 15-30
Severe: Apnea hypopnea index is greater than 30
Differential Diagnosis
• Primary snoring and other sleep disorders
• Insomnia disorder
• Panic attacks
• ADHD
• Substance/medication-induced insomnia or hypersomnia
• Traditional clinical
interview (Kress &
Paylo, 2015)
• Referral to a sleep
disorder center or to a
sleep disorder specialist
for use of laboratory
examinations (Kress &
Paylo, 2015)
• Behavioral
interventions
• Reducing alcohol
consumption and
smoking
• Weight loss and
dieting
• Utilizing oral
applications and
continuous positive
airway pressure
(CPAP)
• Oral surgery
procedures
• Maxillomandibular
Advancement
(MMA)
Breathing-Related Sleep Disorders
•Obstructive Sleep Apnea Hypopnea (DSM Pages 378-383)
Diagnosis Assessment Treatment
Diagnostic Criteria
• Evidence by polysomnography of five or more central
apneas per hour of sleep
• Specify whether:
327.21 Idiopathic central sleep apnea: Repeated episodes
of apneas and hypopneas during sleep caused by
variability in respiratory effort but without evidence of
airway obstruction
786.04 Cheyne-Stokes breathing: A pattern of periodic
crescendo-decrescendo variation in tidal volume that
results in central apneas and hypopneas at a frequency of
a least five events per hour, accompanied by frequent
arousal
780.57 Central sleep apnea comorbid with opiod use:
Attributed to the effects of opiods on the respiratory
rhythm generators in the medulla as well as the
differential effects on hypoxic versus hypercapnic
respiratory drive
• Specify current severity:
Severity of central sleep apnea is graded according to the
frequency of the breathing disturbances as well as the
extent of associated oxygen desturation and sleep
fragmentation that occur as a consequence of repetitive
respiratory disturbances
Differential Diagnosis
• Other breathing-related sleep disorders and sleep
disorders
• Traditional clinical
interview (Kress &
Paylo, 2015)
• Referral to a sleep
disorder center or to a
sleep disorder specialist
for use of laboratory
examinations (Kress &
Paylo, 2015)
• CPAP
Psychopharmacotherapy
• Respiratory stimulants
(theophylline,
acetazolamide)
• Nonbenzodiazepine
hypnotics
Central Sleep Apnea (DSM Pages 383-386)
Diagnosis Assessment Treatment
Diagnostic Criteria
• Polysomnography demonstrates episodes of decreased
respiration associated with eleveated CO2 levels
• Specify whether:
327.24: Idiopathic hypoventilation: Not attributable to any
readily identified condition
327.25 Congential central alveolar hypoventilation: Rare
congenital disorder in which the individual typically
presents in the perinatal period with shallow breathing, or
cyanosis and apnea during sleep
327.26 Comorbid sleep-related hypoventilation: Occurs as a
consequence of a medical condition, such as pulmonary
disorder or a neuromuscular or chest wall disorder, or
medications; also occurs with obesity, where it reflects a
combination of increased work of breathing due to reduced
chest wall compliance and ventilation-perfusion mismatch
and variably reduced ventilator drive; usually characterized
by body mass index of greater than 30 and hypercapnia
during wakefulness, without other evidence of
hypoventilation
• Specify current severity:
Severity is graded according to the degree of hypoxemia and
hyper carbia present during sleep and evidence of end organ
impairment due to these abnormalities; presence of blood
gas abnormalities during wakefulness is an indicator of
greater severity
Differential Diagnosis
• Other medical conditions affecting ventilation
• Other breathing-related sleep disorders
• Traditional clinical
interview (Kress & Paylo,
2015)
• Referral to a sleep
disorder center or to a
sleep disorder specialist
for use of laboratory
examinations (Kress &
Paylo, 2015)
• Thorough substance
assessment
• Noninvasive
ventilation
• Positive pressure
ventilation
Sleep-Related Hypoventilation (DSM Pages 387-390)
References
American Psychiatric Association. (2013). Diagnostic and
statistical manual of mental disorders (5th ed.). Washington, DC:
Author.
Kress, V. E., & Paylo, M. J. (2015). Treating those with mental
disorders: A comprehensive approach to case conceptualization
and treatment. Upper Saddle Ridge, New Jersey: Pearson
Education, Inc.