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Pathology of the Skeletal Pathology of the Skeletal SystemSystem
BursitisBursitis(ber-SIGH-tis)(ber-SIGH-tis)
ChondromaChondroma(kon-DROH-(kon-DROH-
mah)mah)
Inflammation of Inflammation of bursa caused by bursa caused by repetitive repetitive movementsmovements
Chondr=cartilageChondr=cartilage Oma=tumorOma=tumor Slow-growing benign Slow-growing benign
tumor that develops tumor that develops in cartilagein cartilage
Hallux valgusHallux valgus(HAL-ucks VAL-guss)(HAL-ucks VAL-guss)
LuxationLuxation(luck-SAY-shun)(luck-SAY-shun)
SubluxationSubluxation
Common name- bunionCommon name- bunion Abnormal enlargement Abnormal enlargement
of the joint at the base of the joint at the base of the big toe. Shift in of the big toe. Shift in the joint creates the joint creates pressure on other toespressure on other toes
AKA dislocationAKA dislocation Dislocation or Dislocation or
displacement of a bone displacement of a bone from its joint.from its joint.
Partial displacement of Partial displacement of a bone from its jointa bone from its joint
ArthritisArthritis
Gouty ArthritisGouty Arthritis
An inflammatory An inflammatory condition of one or condition of one or more jointsmore joints
AKA GoutAKA Gout Arthritis associated Arthritis associated
with the formation with the formation of uric acid crystals of uric acid crystals in the joint as a in the joint as a result of excess uric result of excess uric acid in the bloodacid in the blood
OsteoarthritisOsteoarthritis Aka wear and tear Aka wear and tear arthritisarthritis
A degenerative A degenerative joint disease that is joint disease that is commonly commonly associated with associated with agingaging
Rheumatoid Rheumatoid ArthritisArthritis
An autoimmune An autoimmune disorderdisorder
Synovial membranes Synovial membranes are inflamed and are inflamed and thickened. Other thickened. Other membranes are also membranes are also attacked.attacked.
Joints become Joints become swollen, painful and swollen, painful and immobileimmobile
Herniated diskHerniated disk
(HER-nee-ayt-(HER-nee-ayt-ed)ed)
LumbagoLumbago
(lum-BAY-go)(lum-BAY-go)
AKA ruptured diskAKA ruptured disk Rupture of the Rupture of the
intervertebral disk intervertebral disk that results in that results in pressure on the pressure on the spinal nerve roots.spinal nerve roots.
Low back pain in the Low back pain in the lumbar regionlumbar region
Spinal ColumnSpinal Column
SpondylitisSpondylitis
(spon-dih-LYE-(spon-dih-LYE-tis)tis)
SpondylosisSpondylosis
(spon-dih-LOH-(spon-dih-LOH-sis)sis)
Inflammation of the Inflammation of the vertebraevertebrae
Spondyl=vertebraeSpondyl=vertebrae
Any degenerative Any degenerative condition of the condition of the vertebraevertebrae
Spina bifidaSpina bifida
(SPY-nah BIF-ih-(SPY-nah BIF-ih-dah)dah)
Congenital defect Congenital defect that occurs during that occurs during early pregnancyearly pregnancy
Spinal canal does Spinal canal does not close around not close around the spinal cordthe spinal cord
Often caused by Often caused by lack of folic acid lack of folic acid during 1during 1stst 3 months 3 months of pregnancy. of pregnancy.
Curvatures of the spineCurvatures of the spine
KyphosisKyphosis
(kye-FOH-sis)(kye-FOH-sis)
LordosisLordosis
(lor-DOH-sis)(lor-DOH-sis)
Abnormal increase Abnormal increase in outward curve of in outward curve of thoracic spine.thoracic spine.
AKA Humpback or AKA Humpback or dowager’s humpdowager’s hump
Kyph=humpKyph=hump Abnormal increase Abnormal increase
in forward curve of in forward curve of lower lumbar spinelower lumbar spine
AKA swaybackAKA swayback Lord=bent Lord=bent
backwardbackward
ScoliosisScoliosis
(skoh-lee-OH-sis)(skoh-lee-OH-sis)
Abnormal lateral Abnormal lateral (sideways) curve (sideways) curve of spineof spine
Scoli=curvedScoli=curved
Bone conditionsBone conditions OsteitisOsteitis
(oss-tee-EYE-tis)(oss-tee-EYE-tis)
OsteomyelitisOsteomyelitis
(oss-tee-oh-my-LYE-(oss-tee-oh-my-LYE-tis)tis)
Inflamation of Inflamation of bonebone
Inflammation of Inflammation of the bone and the bone and bone marrowbone marrow
Paget’s Paget’s DiseaseDisease
(PAJ-its)(PAJ-its)
AKA oseitis AKA oseitis deformansdeformans
Cause unknownCause unknown Disease Disease
characterized by characterized by extensive bone extensive bone destruction followed destruction followed by abnormal bone by abnormal bone repair.repair.
Bones become Bones become deformed and deformed and weakened/may bend weakened/may bend or break easilyor break easily
PeriostitisPeriostitis(pehr-ee-oss-TYE-(pehr-ee-oss-TYE-
tis)tis)
RicketsRickets(RICK-ets)(RICK-ets)
Inflammation of Inflammation of periosteumperiosteum
Peri-surroundingPeri-surrounding Ost-boneOst-bone Caused by calcium Caused by calcium
and vitamin D and vitamin D deficiency in early deficiency in early childhoodchildhood
Results in Results in demineralized demineralized bones and related bones and related deformitiesdeformities
TalipesTalipes
(TAL-ih-peez)(TAL-ih-peez)
Aka clubfootAka clubfoot Congenital Congenital
deformity in which deformity in which the foot may be the foot may be turned outward or turned outward or inwardinward
Tumors of BonesTumors of Bones
MyelomaMyeloma
(my-eh-LOH-mah)(my-eh-LOH-mah)
Malignant tumor Malignant tumor made of cells made of cells from the blood-from the blood-forming tissue of forming tissue of the bone marrowthe bone marrow
Usually Usually progressive and progressive and often fataloften fatal
OsteoporosisOsteoporosis
OsteoporosisOsteoporosis
(oss-tee-oh-poh-(oss-tee-oh-poh-ROH-sis)ROH-sis)
Loss of bone density Loss of bone density and an increase in and an increase in bone porositybone porosity
Usually associated Usually associated with agingwith aging
-porosis = porous -porosis = porous conditioncondition
FracturesFractures
FractureFracture
Greenstick Greenstick fracturefracture
Abbreviated FxAbbreviated Fx A broken boneA broken bone Aka incomplete Aka incomplete
fracturefracture Bone is partially Bone is partially
bent and only bent and only partially brokenpartially broken
Occurs mostly in Occurs mostly in childrenchildren
Closed fractureClosed fracture
Open fractureOpen fracture
Aka simple or complete Aka simple or complete fracturefracture
Bone is broken but Bone is broken but there is no open wound there is no open wound in the skinin the skin
Aka compound fractureAka compound fracture A fracture where the A fracture where the
bone is broken and bone is broken and there is an open wound there is an open wound in the skinin the skin
Comminuted Comminuted fracturefracture
Compression Compression fracturefracture
Spiral fractureSpiral fracture
Bone is splintered or Bone is splintered or crushed into small crushed into small piecespieces
Occurs when the Occurs when the bone is pressed bone is pressed together on itselftogether on itself
Fracture in which the Fracture in which the bone has been bone has been twisted aparttwisted apart
Occurs as a result of Occurs as a result of a sever twisting a sever twisting motion or sports motion or sports injuryinjury
Stress Stress fracturefracture
Small crack in bones Small crack in bones that develops from that develops from chronic, excessive chronic, excessive impactimpact
Usually due to Usually due to sports injurysports injury
Diagnostic proceduresDiagnostic procedures ArthroscopyArthroscopy(ar-THROS-koh-pee)(ar-THROS-koh-pee)
Bone density Bone density testingtesting
Visual exam of the Visual exam of the internal structure of a internal structure of a joint using an joint using an arthroscopearthroscope
Aka bone mass Aka bone mass measurementmeasurement
Use of several types of Use of several types of radiation tests to radiation tests to determine bone density.determine bone density.
Tests are for conditions Tests are for conditions like osteoporosis, like osteoporosis, osteomalacia, and osteomalacia, and Paget’s diseasePaget’s disease
Bone marrow Bone marrow biopsybiopsy
Performed by Performed by inserting a needle into inserting a needle into the hipbone or the hipbone or sternum and removing sternum and removing bone marrow cells bone marrow cells
Tells why blood cells Tells why blood cells are abnormal or to are abnormal or to find a bone marrow find a bone marrow donor match.donor match.
Ultrasonic bone Ultrasonic bone density testingdensity testing
Bone sonometer.Bone sonometer. Uses sound waves Uses sound waves
to take to take measurements of measurements of the heel bonethe heel bone
Screening test for Screening test for osteoporosis or osteoporosis or other bone mass other bone mass loss conditionsloss conditions
MedicationsMedications
Nonsteroidal anti-Nonsteroidal anti-inflammatory inflammatory drugsdrugs
NSAIDsNSAIDs Used to control pain Used to control pain
and reduce and reduce inflammation and inflammation and swellingswelling
Meds in this group Meds in this group may also thin blood may also thin blood and attack stomach and attack stomach lininglining
Ex: aspirin Ex: aspirin
Acetaminophen Acetaminophen
COX-2 COX-2 inhibitorsinhibitors
Controls pain but Controls pain but without side effects without side effects of NSAIDsof NSAIDs
Does not reduce Does not reduce inflammationinflammation
Newer class of medsNewer class of meds Control pain and Control pain and
inflammation of inflammation of arthritisarthritis
Reduce side effects Reduce side effects of NSAIDsof NSAIDs
Bone marrow transplantsBone marrow transplants
AKA stem cell AKA stem cell transplanttransplant
Used to treat some Used to treat some types of cancers like types of cancers like leukemia and leukemia and lymphomalymphoma
Cancer is destroyed Cancer is destroyed with radiationwith radiation
Healthy bone marrow Healthy bone marrow cells are transfused cells are transfused into recipient’s blood into recipient’s blood and migrate to spongy and migrate to spongy bone where they growbone where they grow
Autologous Autologous transplantstransplants
Allogenic Allogenic transplanttransplant
Most frequent typeMost frequent type Uses some of patient’s Uses some of patient’s
own bone marrow that own bone marrow that was harvested before was harvested before treatment startedtreatment started
Used if patient’s own Used if patient’s own bone marrow can’t be bone marrow can’t be usedused
Uses bone marrow donorUses bone marrow donor Needs to be perfect Needs to be perfect
match or recipient’s body match or recipient’s body will reject the transplantwill reject the transplant
JointsJoints
Chondroplasty Chondroplasty
(KON-droh-plas-(KON-droh-plas-tee)tee)
SynovectomySynovectomy (sin-oh-VECK-(sin-oh-VECK-
toh-mee)toh-mee)
Surgical repair of Surgical repair of cartilagecartilage
Surgical removal of Surgical removal of a synovial a synovial membrane from a membrane from a jointjoint
Repairs joints Repairs joints damaged by damaged by rheumatoid arthritisrheumatoid arthritis
Arthrodesis Arthrodesis (ar-throh-DEE-sis)(ar-throh-DEE-sis)
Joint ReplacementJoint Replacement
Revision surgeryRevision surgery
Fusion or surgical Fusion or surgical ankylosisankylosis
Surgical procedure to Surgical procedure to stiffen a joint or join stiffen a joint or join spinal vertebraespinal vertebrae
Replacement part is Replacement part is prosthesis or implantprosthesis or implant
Substitute for a disease Substitute for a disease of missing part of the of missing part of the bodybody
Replacement of a worn Replacement of a worn or failed implantor failed implant
BonesBones
Craniotomy Craniotomy Aka bone flapAka bone flap Surgical incision Surgical incision
or opening into or opening into the skull the skull performed to performed to gain access to gain access to part of the brainpart of the brain
OsteotomyOsteotomy Surgical incision or Surgical incision or sectioning of a sectioning of a bonebone
May be performed May be performed to realign a joint to realign a joint damaged by damaged by arthritisarthritis
Treatment of fracturesTreatment of fractures
Manipulation Manipulation AKA closed reductionAKA closed reduction Attempted Attempted
realignment of bone realignment of bone involved in a fracture involved in a fracture or dislocationor dislocation
Bone is returned to Bone is returned to normal alignment by normal alignment by manually applied manually applied forces and is then forces and is then put in a castput in a cast
External External FixationFixation
Procedure where Procedure where pins are placed pins are placed through the soft through the soft tissues and bone so tissues and bone so an external an external appliance can be appliance can be used to hold the used to hold the bones in place bones in place during healingduring healing
Removed after bone Removed after bone healsheals
Internal Internal FixationFixation
Aka open reduction Aka open reduction internal fixationinternal fixation
Procedure where Procedure where pins or a plate are pins or a plate are placed directly into placed directly into the bone to hold the the bone to hold the broken pieces in broken pieces in place.place.
Not removed after Not removed after fracture healsfracture heals