Embed Size (px)
Citation preview
31HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
The new i-Series food safety analyzers care for consumer protection and product safety:They support the need for fast, high-sensitiv -ity examinations for controlled componentssuch as mycotoxins and synthetic antimicro-bials con taminating the raw materials forfood products. The food safety analyzers arebased on the i-Series of integrated UHPLCsystems.
Efficient analysis of contaminants in food including sample preparation
www.shimadzu.eu / i-care
High-sensitivity detection of mycotoxins and synthetic antimicrobialsat maximum residue levels as regulated by EU standards
Rapid processing of large amounts of data using pre-set method, batch and report files
Results and reports available immediatelyas soon as each analysis is finished
care
Shimadzu_HPLC-Kongress_i-Series:Layout 1 10.05.17 15:19 Seite 1
Sun
day,
18
June
15:00
– 19
:10
Cong
ress
Hal
l
Open
ing
plen
ary
sess
ion
Chai
rs: M
icha
l Hol
čape
k, Fr
antiš
ek Fo
ret,
Pave
l Jan
dera
, Pet
er J.
Sch
oenm
aker
s, Gé
rard
Hop
fgar
tner
15:00
– 15
:20Ar
t per
form
ance
Sp
onso
red
by
15:20
– 15
:35W
elco
me
from
chai
rmen
15:35
– 16
:00Aw
ard
cere
mon
ies
Mart
in M
edal
, Silv
er Ju
bile
e Me
dal,
Uwe
Neue
Awa
rd, G
eorg
es G
uioc
hon
Facu
lty Fe
llows
hip,
Mem
ory
of J.
J. Ki
rkla
nd, J
.F.K.
Hub
er L
ectu
re A
ward
16:00
– 16
:40Ge
rt D
esm
et
Curr
ent s
tate
and
futu
re d
irect
ions
in li
quid
chro
mat
ogra
phy
16:40
– 17
:10Co
ffee
brea
k
17:10
– 17
:50Zo
ltán
Taká
tsAm
bien
t and
LC-M
S lip
idom
ic p
rofil
ing
of cl
inic
al sa
mpl
es –
new
era
in ca
ncer
dia
gnos
tics
17:50
– 18
:30Pa
t San
dra
The
LC to
olbo
x fo
r pro
tein
bio
phar
mac
eutic
al ch
arac
teriz
atio
n
18:30
– 19
:10Pe
ter A
. Will
isSe
arch
ing
for l
ife o
n oc
ean
world
s with
liqu
id p
hase
sepa
ratio
n sy
stem
s
19:10
– 21
:00W
elco
me
mix
er
Scie
ntifi
c Pr
ogra
m
32 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Mon
day,
19
June
8:30
– 10
:00
Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 1
FUN
1HY
P 1
APP
1Ch
arac
teriz
atio
n of
HPL
C st
atio
nary
pha
ses
– In
mem
ory
of Ja
ck K
irkla
ndCh
airs
: Bar
ry L
. Kar
ger,
Joe
DeSt
efan
o
Ion
mob
ility
in LC
/MS
Chai
rs: A
lexa
nder
Mak
arov
, Kar
el L
emr
Fore
nsic
s, do
ping
and
toxi
colo
gyCh
airs
: Ger
hard
Scr
iba,
Chr
istia
n Kl
ampfl
Keyn
ote
08:30
– 09
:00At
tila
Felin
ger
Mass
tran
sfer
pro
pert
ies o
f zwi
tterio
nic
chira
l sta
tiona
ry p
hase
sUn
ivers
ity of
Péc
sHu
ngar
y
Géra
rd H
opfg
artn
erDi
ffere
ntia
l mob
ility
spec
trom
etry
– m
ass
spec
trom
etry
as a
n or
thog
onal
sepa
ratio
n di
men
sion
for o
mic
sUn
ivers
ity of
Gen
eva
Switz
erla
nd
Mario
The
vis
Test
ing
non-
appr
oved
subs
tanc
es
usin
g al
tern
ativ
e m
atric
es a
nd li
quid
ch
rom
atog
raph
y / h
igh-
and
low-
reso
lutio
n ta
ndem
mas
s spe
ctro
met
ry in
dop
ing
cont
rols
Germ
an S
port
Unive
rsity
Colo
gne
Germ
any
Oral
109
:00 –
09:20
Barr
y Bo
yes
Impr
ovin
g bi
omol
ecul
e se
para
tions
with
su
perfi
cial
ly p
orou
s sili
ca p
artic
les
Adva
nced
Mat
erial
s Tec
hnol
ogy,
Inc.
USA
Oliv
er S
chm
itzLC
+LC-
and
GC+
GC-I
M-qT
OF-M
S as
a p
oten
tial t
ool i
n no
n-ta
rget
ana
lysi
sUn
ivers
ity of
Duis
burg
-Ess
enGe
rman
yIn
vite
d Or
al
Andr
eas T
hom
asDo
ping
cont
rol a
naly
sis o
f pro
hibi
ted
pept
ide
drug
s afte
r sop
hist
icat
ed
met
abol
ism
stud
ies b
y m
eans
of l
iqui
d ch
rom
atog
raph
y co
uple
d to
HR-
MS/M
SGe
rman
Spo
rt Un
ivers
ity Co
logn
eGe
rman
y
Oral
209
:20 –
09:40
Jose
ph G
lajc
hCh
arac
teriz
atio
n of
HPL
C st
atio
nary
pha
ses:
Ho
w th
is ca
n le
ad to
nov
el a
nd im
prov
ed
chro
mat
ogra
phy
Mom
enta
Pha
rmac
eutic
als
USA
Invi
ted
Oral
Alex
ey M
akar
ovUs
ing
IMS-
MS co
mbi
ned
with
size
-exc
lusi
on
chro
mat
ogra
phy
and
diffe
rent
ial h
ydro
gen–
deut
eriu
m e
xcha
nge
for s
emi-
auto
mat
ed
scre
en o
f glo
bal p
rote
in co
nfor
mat
iona
l ch
ange
s in
solu
tion
Merc
k Sha
rp &
Doh
me C
orp.
USA
Fede
rico
Ponz
etto
Expl
orin
g bl
ood
ster
oido
mic
s for
th
e im
prov
emen
t of t
he a
thle
te b
iolo
gica
l pa
sspo
rt st
eroi
dal m
odul
eCH
UV –
Unive
rsity
of La
usan
neSw
itzer
land
Oral
309
:40 –
10:00
Mart
in G
ilar
Expe
rimen
tal e
valu
atio
n of
mic
roflu
idic
LC
colu
mn
perf
orm
ance
: Str
aigh
t ver
sus
serp
entin
e ch
anne
lsWa
ters
Corp
orat
ionUS
AIn
vite
d Or
al
Qian
g Ma
Com
preh
ensi
ve se
para
tion
and
anal
ysis
of
non
ioni
c sur
fact
ants
by
ultr
a-hi
gh p
erfo
rman
ce su
perc
ritic
al fl
uid
chro
mat
ogra
phy
com
bine
d wi
th io
n m
obili
ty
spec
trom
etry
-mas
s spe
ctro
met
ryCh
ines
e Aca
dem
y of I
nspe
ction
and
Quar
antin
eCh
ina
Marie
ke D
e Bo
eck
Valid
atio
n of
a fa
st io
nic l
iqui
d-ba
sed
disp
ersi
ve li
quid
-liq
uid
mic
roex
trac
tion
proc
edur
e co
mbi
ned
with
LC-M
S/MS
ana
lysi
s for
the
quan
tifica
tion
of b
enzo
diaz
epin
es in
who
le b
lood
KU Le
uven
Belg
ium10
:00 –
10:30
Coffe
e br
eak,
Exh
ibiti
on, P
oste
rs
Meet
ing
Hall
VSe
ssion
1YO
U 1
2D-L
CCh
airs
: Pau
la D
ugo,
Bob
Piro
k
Tuto
rial
8:30 –
09:10
Mark
R. S
chur
eTw
o-di
men
sion
al ch
rom
atog
raph
y:
A tu
toria
lKr
oung
old
Analy
tical
, Inc.
USA
Shor
t ora
l 109
:10 –
09:22
Rena
ta G
erha
rdt
Chip
-bas
ed H
PLC
with
an
inte
grat
ed d
ropl
et
inte
rfac
e fo
r sur
face
enh
ance
d Ra
man
de
tect
ion
Unive
rsity
of Le
ipzig
Germ
any
Shor
t ora
l 209
:22 –
09:34
Elis
enda
Forn
ells
Mem
bran
e ev
apor
ativ
e in
terf
ace
for L
CxLC
Unive
rsity
of Ta
sman
iaAu
stra
lia
Shor
t ora
l 309
:34 –
09:46
Niko
line
Juul
Nie
lsen
Incr
easi
ng fl
exib
ility
in tw
o-di
men
sion
al
liqui
d ch
rom
atog
raph
y by
pul
sed
elut
ion
of th
e fir
st d
imen
sion
(Pul
sed-
elut
ion
2D-L
C)Un
ivers
ity of
Cop
enha
gen
Denm
ark
Shor
t ora
l 409
:46 –
09:58
Doug
las R
icha
rdso
nTw
o-di
men
tiona
l LC
for a
naly
sis
of m
onoc
lona
l ant
ibod
y du
ring
biop
roce
ss
deve
lopm
ent
MSD
USA
33HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Mon
day,
19
June
10:3
0 – 12
:00 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
2FU
N 2
HYP
2AP
P 2
Multi
-dim
ensi
onal
sepa
ratio
nsCh
airs
: Kel
ly Z
hang
, Dwi
ght S
toll
Ion
supp
ress
ion
and
mat
rix-e
ffect
s in
sepa
ratio
n –
MSCh
airs
: Mar
io T
hevi
s, Ol
iver
Sch
mitz
Prot
eom
ics
Chai
rs: S
ebas
tiaan
Eel
tink,
Yin
g Ge
Keyn
ote
10:30
– 11
:00Pe
ter J
. Sch
oenm
aker
sMu
lti-d
imen
sion
al li
quid
chro
mat
ogra
phy
– to
ward
s a m
illio
n pe
aks
Unive
rsity
of A
mst
erda
mTh
e Net
herla
nds
Jean
-Luc
Veu
they
Eval
uatio
n of
mat
rix e
ffect
s in
HILI
C, R
PLC
and
SFC-
MSUn
ivers
ity of
Gen
eva,
Unive
rsity
of La
usan
neSw
itzer
land
John
Yate
sPr
otei
n-pr
otei
n in
tera
ctio
n st
udie
s of
dis
ease
net
work
sTh
e Scr
ipps R
esea
rch
Inst
itute
USA
Oral
111
:00 –
11:20
Mark
R. S
chur
eSi
ze e
xclu
sion
chro
mat
ogra
phy
with
supe
rfici
ally
por
ous p
artic
les
Krou
ngol
d An
alytic
al, In
c.US
AIn
vite
d Or
al
Luci
e No
váko
váDe
velo
pmen
t of U
HPSF
C-MS
met
hod
for h
igh-
thro
ughp
ut a
naly
sis
of v
itam
in E
isom
ers a
nd e
valu
atio
n of
mat
rix e
ffect
s whe
n us
ing
diffe
rent
sa
mpl
e pr
epar
atio
n ap
proa
ches
Char
les U
nive
rsity
, Fac
ulty
of P
harm
acy
Czec
h Re
publ
ic
Chris
tian
G. H
uber
Prot
eom
e- a
nd p
hosp
hopr
oteo
me
anal
ysis
of
onk
ogen
ic si
gnal
ing
path
ways
Unive
rsity
of S
alzb
urg
Aust
riaIn
vite
d Or
al
Oral
211
:20 –
11:40
Bob
Piro
k Ex
tend
ed m
ulti-
dim
ensi
onal
liqu
id-
chro
mat
ogra
phy
syst
ems f
or co
mpr
ehen
sive
an
alys
is o
f com
plex
pol
ymer
ic
nano
part
icle
sUn
ivers
ity of
Am
ster
dam
The N
ethe
rland
s
Aim
in Ta
nHo
w m
uch
sepa
ratio
n fo
r LC–
MS/M
S qu
antit
ativ
e bi
oana
lysi
s?Nu
cro-
Tech
nics
Cana
da
Marc
el K
wia
tkow
ski
Bette
r acc
ess t
o pr
oteo
form
s by
cold
va
poriz
atio
n of
tiss
ues w
ith p
icos
econ
d-in
frar
ed-l
aser
(PIR
L) a
blat
ion
Unive
rsity
Med
ical C
ente
r Gro
ning
enTh
e Net
herla
nds
Oral
311
:40 –
12:00
Andr
e de
Vill
iers
Pare
to-o
ptim
isat
ion
of H
ILIC
×RP-
LC
sepa
ratio
ns: E
xper
imen
tal v
erifi
catio
n an
d ap
plic
atio
n to
phe
nolic
ana
lysi
sSt
elle
nbos
ch U
nive
rsity
Sout
h Af
rica
Germ
an G
omez
-Rio
sCa
n HP
LC-M
S be
repl
aced
by
dire
ct co
uplin
g of
SPM
E to
MS?
Inve
stig
atin
g ch
alle
ngin
g ca
ses
Unive
rsity
of W
ater
loo
Cana
da
Mort
eza
Khal
edi
Surf
acta
nt-f
ree
coac
erva
tion
of n
atur
al ce
ll m
embr
anes
for f
acile
, sel
ectiv
e ex
trac
tion,
an
d en
richm
ent o
f int
egra
l mem
bran
e pr
otei
ns in
pro
teom
ics
Unive
rsity
of Te
xas-
Arlin
gton
USA
12:00
– 14
:00Lu
nch,
Exh
ibiti
on, P
oste
rs, V
endo
r sem
inar
s
Meet
ing
Hall
VSe
ssion
2YO
U 2
Sepa
ratio
n m
echa
nism
sCh
airs
: Mar
tin G
ilar,
Tere
nce
Hetz
el
Tuto
rial
10:30
– 11
:10An
drew
Alp
ert
Effec
t of s
alts
on
rete
ntio
n of
neu
tral
so
lute
s in
HILI
CPo
lyLC,
Inc.
USA
Shor
t ora
l 111
:10 –
11:22
Sand
er D
erid
der
Num
eric
al st
udy
of th
e th
erm
al co
nduc
tivity
of
colu
mns
pac
ked
with
fully
por
ous
and
supe
rfici
ally
por
ous p
artic
les
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Shor
t ora
l 211
:22 –
11:34
Kata
rzyn
a Kr
zem
ińsk
aDu
al re
tent
ion
mec
hani
sm o
n st
atio
nary
ph
ases
with
em
bedd
ed p
olar
gro
upNi
cola
us Co
pern
icus U
nive
rsity
Pola
nd
Shor
t ora
l 311
:34 –
11:46
Khac
-Lon
g Ng
uyen
Tran
spor
t of m
olec
ules
of d
iffer
ent s
izes
thro
ugh
mon
olith
ic, c
ore-
shel
l and
por
ous
silic
a co
lum
ns. E
ffect
of p
orou
s sili
ca
arch
itect
ure
Inpa
ct gr
oup
Franc
eSh
ort o
ral 4
11:46
– 11
:58Sz
ymon
Boc
ian
Solv
atio
n pr
oces
ses i
n liq
uid
chro
mat
ogra
phy
– th
e im
port
ance
an
d m
easu
rem
ent
Nico
laus
Cope
rnicu
s Uni
vers
ity in
Toru
ńPo
land
34 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Mon
day,
19
June
14:0
0 – 15
:30 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
3FU
N 3
HYP
3AP
P 3
Mech
anis
ms o
f mas
s tra
nspo
rt p
heno
men
aCh
airs
: Pav
el Ja
nder
a, Fr
eder
ic Ly
nen
Sepa
ratio
n –
high
-res
olut
ion
MSCh
airs
: Mic
hal H
olča
pek,
Zoltá
n Ta
káts
Sam
ple
prep
arat
ion
and
auto
mat
ion
Chai
rs: E
mily
Hild
er, D
oo S
oo C
hung
Keyn
ote
14:00
– 14
:30Fa
bric
e Gr
itti
Com
bini
ng so
lven
t and
non
-uni
form
te
mpe
ratu
re g
radi
ents
to im
prov
e pe
ak
capa
city
in m
icro
fluid
ic se
para
tions
Wate
rs Co
rpor
ation
USA
Alex
ande
r Mak
arov
Orbi
trap
tech
nolo
gy in
LC/M
S an
d GC
/MS:
On
the
road
to h
igh-
reso
lutio
n in
eve
ry la
bTh
erm
o Fish
er S
cient
ific
Germ
any
Janu
sz P
awlis
zyn
Why
are
thin
coat
ed sa
mpl
ing/
extr
actio
n de
vice
s with
bio
com
patib
le so
rben
ts
well
suite
d fo
r cou
plin
g of
bio
logi
cal
syst
ems t
o liq
uid
chro
mat
ogra
phy/
mas
s sp
ectr
omet
ry?
Unive
rsity
of W
ater
loo
Cana
daOr
al 1
14:30
– 14
:50De
irdre
Cab
oote
rEx
perim
enta
l met
hodo
logi
es
for t
he a
sses
smen
t of i
ndiv
idua
l mas
s tr
ansf
er p
heno
men
a re
visi
ted
Unive
rsity
of Le
uven
Belg
iumIn
vite
d Or
al
Ying
Ge
Top–
down
pro
teom
ics o
f lar
ge p
rote
ins
up to
223
kda
ena
bled
by
seria
l size
ex
clus
ion
chro
mat
ogra
phy
stra
tegy
Unive
rsity
of W
iscon
sin-M
adiso
nUS
AIn
vite
d Or
al
Gong
ke L
iNo
vel o
nlin
e sa
mpl
e pr
epar
atio
n m
edia
fo
r com
plic
ated
sam
ples
ana
lysi
s co
uplin
g wi
th h
igh-
perf
orm
ance
liqu
id
chro
mat
ogra
phy
Sun Y
at-s
en U
nive
rsity
China
Invi
ted
Oral
Oral
214
:50 –
15:10
Szab
olcs
Feke
teSy
stem
ban
d br
oade
ning
and
its i
mpa
ct
in m
oder
n si
ze-e
xclu
sion
chro
mat
ogra
phy
of p
rote
ins
Unive
rsity
Of G
enev
aSw
itzer
land
Gove
rt S
omse
nHi
ghly
sele
ctiv
e ch
arac
teriz
atio
n of
inta
ct
prot
eofo
rms b
y HI
LIC-
MSVr
ije U
nive
rsite
it Am
ster
dam
The N
ethe
rland
s
Mass
imo
Morb
idel
liIs
ofor
m e
nric
hmen
t by
recy
clin
g ch
rom
atog
raph
yIn
stitu
te fo
r Che
mica
l and
Bioe
ngin
eerin
gSw
itzer
land
Invi
ted
Oral
Oral
315
:10 –
15:30
Julia
Ryb
kaSu
rfac
e di
ffusi
on o
f aro
mat
ic h
ydro
carb
on
anal
ytes
in re
vers
ed-p
hase
liqu
id
chro
mat
ogra
phy
Phili
pps-
Unive
rsitä
t Mar
burg
Germ
any
Chris
tian
Lans
hoef
tA
gene
ric h
ybrid
LBA
-LC-
HRMS
-bas
ed
work
flow
for m
ultip
lexe
d hI
gG1
quan
tifica
tion
in p
re-c
linic
al sp
ecie
s di
rect
ly a
t the
inta
ct p
rote
in le
vel
Nova
rtis P
harm
a AG
Switz
erla
nd
Astr
id G
jels
tad
Does
par
alle
l art
ifici
al li
quid
mem
bran
e ex
trac
tion
mat
ch th
e re
quire
men
ts fo
r an
app
licab
le a
nd h
igh-
thro
ughp
ut sa
mpl
e pr
epar
atio
n m
etho
d fr
om b
iolo
gica
l m
atric
es?
Unive
rsity
of O
sloNo
rway
15:30
– 16
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Meet
ing
Hall
VSe
ssion
3YO
U 3
Prot
eom
ics
Chai
rs: N
orm
an D
ovic
hi, P
aige
Mal
ec
Tuto
rial
14:00
– 14
:40Ba
rry
L. K
arge
rTh
e ro
le o
f sep
arat
ions
in p
rote
in a
nd
prot
eom
ic m
ass s
pect
rom
etric
ana
lysi
sNo
rthea
ster
n Un
ivers
ityUS
A
Shor
t ora
l 114
:40 –
14:52
Adam
Kec
skem
eti
Char
acte
rizat
ion
of a
pol
y(di
met
hyls
iloxa
ne)
mic
roflu
idic
chip
cont
aini
ng im
mob
ilize
d tr
ypsi
n fo
r rap
id p
rote
in d
iges
tion
Unive
rsity
of D
ebre
cen
Hung
ary
Shor
t ora
l 214
:52 –
15:04
Jana
Zem
enov
áNo
vel a
ppro
ach
to d
eter
min
e lip
idat
ed
anal
ogs o
f pro
lact
in-r
elea
sing
pep
tide
via
LC-M
S us
ing
mon
olith
ic co
lum
nCz
ech
Acad
emy o
f Scie
nces
Czec
h Re
publ
ic
Shor
t ora
l 315
:04 –
15:16
Peng
YuTr
inity
P1
mix
ed m
ode
chro
mat
ogra
phy
enab
les m
ass s
pect
rom
etry
com
patib
le
orth
ogon
al p
eptid
e se
para
tion
to re
vers
ed
phas
eTe
chni
sche
Uni
vers
ität M
ünch
enGe
rman
ySh
ort o
ral 4
15:16
– 15
:28El
izave
ta S
olov
yeva
Pred
ictiv
e ch
rom
atog
raph
y of
pep
tides
fo
r opt
imize
d fr
actio
natio
n in
bot
tom
-up
prot
eom
ics
Mosc
ow In
stitu
te of
Phy
sics a
nd Te
chno
logy
Russ
ian Fe
dera
tion
35HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Mon
day,
19
June
14:0
0 – 15
:30 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
3FU
N 3
HYP
3AP
P 3
Mech
anis
ms o
f mas
s tra
nspo
rt p
heno
men
aCh
airs
: Pav
el Ja
nder
a, Fr
eder
ic Ly
nen
Sepa
ratio
n –
high
-res
olut
ion
MSCh
airs
: Mic
hal H
olča
pek,
Zoltá
n Ta
káts
Sam
ple
prep
arat
ion
and
auto
mat
ion
Chai
rs: E
mily
Hild
er, D
oo S
oo C
hung
Keyn
ote
14:00
– 14
:30Fa
bric
e Gr
itti
Com
bini
ng so
lven
t and
non
-uni
form
te
mpe
ratu
re g
radi
ents
to im
prov
e pe
ak
capa
city
in m
icro
fluid
ic se
para
tions
Wate
rs Co
rpor
ation
USA
Alex
ande
r Mak
arov
Orbi
trap
tech
nolo
gy in
LC/M
S an
d GC
/MS:
On
the
road
to h
igh-
reso
lutio
n in
eve
ry la
bTh
erm
o Fish
er S
cient
ific
Germ
any
Janu
sz P
awlis
zyn
Why
are
thin
coat
ed sa
mpl
ing/
extr
actio
n de
vice
s with
bio
com
patib
le so
rben
ts
well
suite
d fo
r cou
plin
g of
bio
logi
cal
syst
ems t
o liq
uid
chro
mat
ogra
phy/
mas
s sp
ectr
omet
ry?
Unive
rsity
of W
ater
loo
Cana
daOr
al 1
14:30
– 14
:50De
irdre
Cab
oote
rEx
perim
enta
l met
hodo
logi
es
for t
he a
sses
smen
t of i
ndiv
idua
l mas
s tr
ansf
er p
heno
men
a re
visi
ted
Unive
rsity
of Le
uven
Belg
iumIn
vite
d Or
al
Ying
Ge
Top–
down
pro
teom
ics o
f lar
ge p
rote
ins
up to
223
kda
ena
bled
by
seria
l size
ex
clus
ion
chro
mat
ogra
phy
stra
tegy
Unive
rsity
of W
iscon
sin-M
adiso
nUS
AIn
vite
d Or
al
Gong
ke L
iNo
vel o
nlin
e sa
mpl
e pr
epar
atio
n m
edia
fo
r com
plic
ated
sam
ples
ana
lysi
s co
uplin
g wi
th h
igh-
perf
orm
ance
liqu
id
chro
mat
ogra
phy
Sun Y
at-s
en U
nive
rsity
China
Invi
ted
Oral
Oral
214
:50 –
15:10
Szab
olcs
Feke
teSy
stem
ban
d br
oade
ning
and
its i
mpa
ct
in m
oder
n si
ze-e
xclu
sion
chro
mat
ogra
phy
of p
rote
ins
Unive
rsity
Of G
enev
aSw
itzer
land
Gove
rt S
omse
nHi
ghly
sele
ctiv
e ch
arac
teriz
atio
n of
inta
ct
prot
eofo
rms b
y HI
LIC-
MSVr
ije U
nive
rsite
it Am
ster
dam
The N
ethe
rland
s
Mass
imo
Morb
idel
liIs
ofor
m e
nric
hmen
t by
recy
clin
g ch
rom
atog
raph
yIn
stitu
te fo
r Che
mica
l and
Bioe
ngin
eerin
gSw
itzer
land
Invi
ted
Oral
Oral
315
:10 –
15:30
Julia
Ryb
kaSu
rfac
e di
ffusi
on o
f aro
mat
ic h
ydro
carb
on
anal
ytes
in re
vers
ed-p
hase
liqu
id
chro
mat
ogra
phy
Phili
pps-
Unive
rsitä
t Mar
burg
Germ
any
Chris
tian
Lans
hoef
tA
gene
ric h
ybrid
LBA
-LC-
HRMS
-bas
ed
work
flow
for m
ultip
lexe
d hI
gG1
quan
tifica
tion
in p
re-c
linic
al sp
ecie
s di
rect
ly a
t the
inta
ct p
rote
in le
vel
Nova
rtis P
harm
a AG
Switz
erla
nd
Astr
id G
jels
tad
Does
par
alle
l art
ifici
al li
quid
mem
bran
e ex
trac
tion
mat
ch th
e re
quire
men
ts fo
r an
app
licab
le a
nd h
igh-
thro
ughp
ut sa
mpl
e pr
epar
atio
n m
etho
d fr
om b
iolo
gica
l m
atric
es?
Unive
rsity
of O
sloNo
rway
15:30
– 16
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Mon
day,
19
June
16:3
0 – 18
:00 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
4FU
N 4
HYP
4AP
P 4
Stat
iona
ry p
hase
s bas
ed o
n in
orga
nic
supp
orts
Chai
rs: A
ttila
Felin
ger,
Moni
ka D
ittm
an
Multi
dim
ensi
onal
chro
mat
ogra
phy
and
MS co
uplin
gCh
airs
: Pet
er S
choe
nmak
ers,
Mark
Sch
ure
Meta
bolo
mic
sCh
airs
: Koj
i Ots
uka,
Raw
i Ram
auta
r
Keyn
ote
16:30
– 17
:00Jo
e Pe
sek
Aque
ous n
orm
al p
hase
chro
mat
ogra
phy:
Th
e re
liabl
e an
d ru
gged
met
hod
for p
olar
co
mpo
und
anal
ysis
San
Jose
Sta
te U
nive
rstiy
USA
Will
iam
Cra
ig B
yrdw
ell
Com
preh
ensi
ve tw
o-di
men
sion
al li
quid
ch
rom
atog
raph
y wi
th q
uadr
uple
par
alle
l m
ass s
pect
rom
etry
, LC1
MS2
x LC
1MS2
=
LC2M
S4AR
S, Fo
od Co
mpo
sit &
Met
hods
Dev
Lab
USA
Guow
ang
XuMe
tabo
lom
ics:
From
diff
eren
tial m
etab
olite
di
scov
ery
to fu
nctio
nal e
luci
datio
nDa
lian
Inst
itute
of C
hem
ical P
hysic
sCh
ina
Oral
117
:00 –
17:20
Fred
eric
Lyne
nEn
hanc
ing
peak
capa
city
in te
mpe
ratu
re
resp
onsi
ve li
quid
chro
mat
ogra
phy
Ghen
t Uni
vers
ityBe
lgium
Invi
ted
Oral
Dwig
ht S
toll
Impr
ovin
g th
e re
solv
ing
powe
r and
de
tect
ion
sens
itivi
ty o
f two
-dim
ensi
onal
liq
uid
chro
mat
ogra
phy
sepa
ratio
ns
of p
rote
in d
iges
tsGu
stav
us A
dolp
hus C
olle
geUS
AIn
vite
d Or
al
Lian
g Li
Com
preh
ensi
ve a
nd Q
uant
itativ
e Pr
ofilin
g of
the
Hum
an B
lood
Met
abol
ome
from
One
Mi
crol
iter o
f Fin
ger B
lood
Unive
rsity
of A
lber
taCa
nada
Invi
ted
Oral
Oral
217
:20 –
17:40
Alla
Che
rnob
rovk
ina
Reve
alin
g th
e tr
ends
in se
lect
ivity
chan
ges
alte
ring
the
func
tiona
l lay
er o
f nov
el H
ILIC
st
atio
nary
pha
ses
Lom
onos
ov M
osco
w St
ate U
nive
rsity
Russ
ian Fe
dera
tion
Bert
Wou
ters
Impl
emen
tatio
n of
an
imm
obili
sed-
enzy
me
mic
roflu
idic
reac
tor i
n an
inte
grat
ed m
ulti-
dim
ensi
onal
liqu
id ch
rom
atog
raph
y sy
stem
Unive
rsity
of A
mst
erda
mTh
e Net
herla
nds
Daja
na V
ucko
vic
Impr
ovin
g m
etab
olite
cove
rage
in g
loba
l m
etab
olom
ics u
sing
sequ
entia
l ext
ract
ion
Conc
ordia
Uni
vers
ityCa
nada
Oral
317
:40 –
18:00
Estr
ella
San
z Rod
rigue
zPo
rous
silic
a la
yers
ope
n tu
bula
r mul
ti-ch
anne
l cap
illar
ies a
s mic
ro a
naly
tical
pl
atfo
rms f
or se
para
tion
and
extr
actio
nUn
ivers
ity of
Tasm
ania
Aust
ralia
C J V
enka
tram
ani
High
reso
lutio
n an
alys
is o
f lin
ker d
rugs
us
ed in
ant
ibod
y dr
ug co
njug
ates
(ADC
’s)
by 2
D-LC
-MS:
Tran
sitio
n of
2D-
LC-M
S fr
om
rese
arch
to m
ain
stre
am p
harm
aceu
tical
an
alys
isGe
nent
ech
Inc
USA
Paig
e Ma
lec
Deriv
atiza
tion
stra
tegi
es fo
r tar
gete
d m
etab
olom
ics
Unive
rsity
of M
ichiga
nUS
A
18:00
– 20
:00Cz
ech
Beer
Par
ty
Csa
ba H
orvá
th Yo
ung S
cient
ist Aw
ard
final
ists
Meet
ing
Hall
VSe
ssion
4YO
U 4
Sam
ple
prep
arat
ion
Chai
rs: J
anus
z Paw
liszy
n, G
ongk
e Li
Tuto
rial
16:30
– 17
:10Bo
gusl
aw B
usze
wsk
i Si
mila
rity,
sele
ctiv
ity, a
nd sp
ecifi
city
(3s)
–
thre
e di
men
sion
al fa
ctor
det
erm
inin
g HP
LC
reso
lutio
nNi
cola
us Co
pern
icus U
nive
rsity
Pola
nd
Shor
t ora
l 117
:10 –
17:22
Andr
ew Q
uigl
eyDe
term
inat
ion
of se
lect
ed fa
t sol
uble
vi
tam
ins f
rom
bov
ine
milk
usi
ng d
ispe
rsiv
e liq
uid-
liqui
d m
icro
extr
actio
n co
uple
d wi
th
HPLC
-UV
equi
pped
with
a co
re-s
hell
colu
mn
Wate
rford
Inst
itute
of Te
chno
logy
Irela
ndSh
ort o
ral 2
17:22
– 17
:34Sa
ra Te
ngat
tini
Deve
lopm
ent o
f an
HPLC
bio
reac
tor
base
d on
imm
obili
zed
ente
roki
nase
fo
r the
clea
vage
of f
usio
n pr
otei
nsUn
ivers
ity of
Pavia
Italy
Shor
t ora
l 317
:34 –
17:46
Mich
el R
aetz
Auto
mat
ed ro
botic
sam
ple
prep
arat
ion
for m
etab
olom
ics w
ith h
yphe
natio
n to
LC-S
WAT
H/MS
acq
uisi
tion
for p
lasm
a an
d liv
er sa
mpl
esUn
ivers
ity of
Gen
eva
Switz
erla
ndSh
ort o
ral 4
17:46
– 17
:58De
yber
Arl
ey V
arga
s Med
ina
Easy
and
chea
p ap
para
tus f
or th
e off
-lin
e au
tom
atiza
tion
of m
inia
turiz
ed sa
mpl
e pr
epar
atio
n te
chni
ques
Unive
rsida
de d
e São
Paul
oBr
azil
36 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Tues
day,
20
June
8:30
– 10
:00
Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 5
FUN
5HY
P 5
APP
5Su
perc
ritic
al fl
uid
chro
mat
ogra
phy
Chai
rs: D
avy
Guill
arm
e, L
ucie
Nov
ákov
áEl
ectr
odriv
en se
para
tions
– M
SCh
airs
: Mar
ja-L
iisa
Riek
kola
, An
dras
Gut
tman
Chira
l sep
arat
ions
Chai
rs: W
olfg
ang
Lind
ner,
Albe
rto
Cava
zzin
i
Keyn
ote
08:30
– 09
:00Ca
rolin
e W
est
Ions
and
SFC
: An
impr
obab
le m
atch
?Un
ivers
ité d
’Orlé
ans
Franc
e
Jona
than
Sw
eedl
erMe
asur
ing
endo
geno
us D
-am
ino
acid
s in
the
brai
n –
from
bra
in re
gion
s and
in
divi
dual
cells
to ce
llula
r rel
ease
– u
sing
CE
and
LCUn
ivers
ity of
Illin
ois at
Urb
ana-
Cham
paign
USA
Bezh
an C
hank
veta
dze
Rece
nt tr
ends
in a
pplic
atio
n of
pol
ysac
char
ide-
base
d ch
iral s
elec
tors
fo
r liq
uid
phas
e se
para
tion
of e
nant
iom
ers
Tbili
si St
ate U
nive
rsity
Geor
gia
Oral
109
:00 –
09:20
Didi
er T
hiéb
aut
Eval
uatio
n of
alte
rnat
ive
solv
ents
in n
orm
al
phas
e liq
uid
and
supe
rcrit
ical
flui
d ch
rom
atog
raph
y fo
r lip
id cl
asse
s ana
lysi
sES
PCI P
aris
– CNR
S –
PSL R
esea
rch
Unive
rsity
Franc
eIn
vite
d Or
al
Raw
i Ram
auta
rRe
solv
ing
volu
me-
rest
ricte
d m
etab
olom
ics
usin
g sh
eath
less
capi
llary
ele
ctro
phor
esis
-m
ass s
pect
rom
etry
Leide
n Un
ivers
ityTh
e Net
herla
nds
Gerh
ard
Scrib
aCa
pilla
ry e
lect
roph
ores
is
in th
e de
term
inat
ion
of th
e st
ereo
isom
eric
pu
rity
of d
rugs
Fried
rich
Schi
ller U
nive
rsity
Germ
any
Invi
ted
Oral
Oral
209
:20 –
09:40
Abhi
jit Ta
rafd
erMo
delin
g re
tent
ion
beha
vior
und
er so
lven
t gr
adie
nt co
nditi
on in
SFC
Wate
rs Co
rpor
ation
USA
Chris
tian
Neus
üßMa
ss sp
ectr
omet
ric ch
arac
teriz
atio
n of
impu
ritie
s of a
n an
tibod
y se
para
ted
by S
DS-c
apill
ary
siev
ing
elec
trop
hore
sis
usin
g CS
E-CZ
E-MS
Aale
n Un
ivers
ityGe
rman
y
Kenj
i Ham
ase
Thre
e-di
men
sion
al H
PLC
anal
ysis
of a
min
o ac
id e
nant
iom
ers i
n co
mpl
icat
ed re
al w
orld
sa
mpl
esKy
ushu
Uni
vers
ityJa
pan
Oral
309
:40 –
10:00
Char
lene
Mus
cat G
alea
Optim
izatio
n of
tem
pera
ture
and
bac
k-pr
essu
re in
dru
g-im
purit
y pr
ofilin
g by
SFC
: A
resp
onse
surf
ace
desi
gn a
ppro
ach
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Aran
Pau
lus
Capi
llary
ele
ctro
phor
esis
– m
ass
spec
trom
etry
for i
ntac
t mas
s ana
lysi
s of
ant
ibod
ies a
nd a
ntib
ody-
drug
-con
juga
tes
Ther
mo F
isher
Scie
ntifi
cUS
A
Tiva
dar F
arka
sFu
rthe
r stu
dies
on
the
HILI
C ch
arac
ter
of p
olys
acch
arid
e-ba
sed
chira
l sta
tiona
ry
phas
es in
pol
ar o
rgan
ic se
para
tion
mod
ePh
enom
enex
, Inc.
USA
10:00
– 10
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Coffe
e bre
ak sp
onso
red
by
Meet
ing
Hall
VSe
ssion
5YO
U 5
Meta
bolo
mic
s and
lipi
dom
ics
Chai
rs: T
hom
as H
anke
mei
er, M
icha
el W
ittin
g
Tuto
rial
8:30 –
09:10
Lian
g Li
High
-cov
erag
e qu
antit
ativ
e m
etab
olom
ics
usin
g ch
emic
al is
otop
e la
belin
g LC
-MS
Unive
rsity
of A
lber
taCa
nada
Shor
t ora
l 109
:10 –
09:22
Fran
cesc
a Ri
gano
Use
of a
nov
el li
near
rete
ntio
n in
dex
syst
em a
s ide
ntifi
catio
n to
ol in
liqu
id
chro
mat
ogra
phy:
App
licat
ions
in li
pido
mic
sCh
rom
aleo
nt S
.r.L.
Italy
Shor
t ora
l 209
:22 –
09:34
Evel
yn R
ampl
erSi
mul
tane
ous n
on-p
olar
and
pol
ar
lipid
ana
lysi
s by
com
plem
enta
ry o
nlin
e tw
o-di
men
sion
al li
quid
chro
mat
ogra
phy
and
high
reso
lutio
n m
ass s
pect
rom
etry
Unive
rsity
of V
ienna
Aust
riaSh
ort o
ral 3
09:34
– 09
:46Ha
nne
Robe
rg-L
arse
nOx
yste
rols
in ca
ncer
Unive
rsity
of O
sloNo
rway
Shor
t ora
l 409
:46 –
09:58
Tim
Cau
son
Incr
easi
ng p
eak
capa
city
and
sele
ctiv
ity
of LC
-MS
by in
corp
orat
ion
of lo
w-fie
ld
drift
-tub
e io
n m
obili
ty se
para
tion
Unive
rsity
of N
atur
al R
esou
rces
and
Life S
cienc
es
(BOK
U Vie
nna)
Aust
ria
37HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Tues
day,
20
June
8:30
– 10
:00
Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 5
FUN
5HY
P 5
APP
5Su
perc
ritic
al fl
uid
chro
mat
ogra
phy
Chai
rs: D
avy
Guill
arm
e, L
ucie
Nov
ákov
áEl
ectr
odriv
en se
para
tions
– M
SCh
airs
: Mar
ja-L
iisa
Riek
kola
, An
dras
Gut
tman
Chira
l sep
arat
ions
Chai
rs: W
olfg
ang
Lind
ner,
Albe
rto
Cava
zzin
i
Keyn
ote
08:30
– 09
:00Ca
rolin
e W
est
Ions
and
SFC
: An
impr
obab
le m
atch
?Un
ivers
ité d
’Orlé
ans
Franc
e
Jona
than
Sw
eedl
erMe
asur
ing
endo
geno
us D
-am
ino
acid
s in
the
brai
n –
from
bra
in re
gion
s and
in
divi
dual
cells
to ce
llula
r rel
ease
– u
sing
CE
and
LCUn
ivers
ity of
Illin
ois at
Urb
ana-
Cham
paign
USA
Bezh
an C
hank
veta
dze
Rece
nt tr
ends
in a
pplic
atio
n of
pol
ysac
char
ide-
base
d ch
iral s
elec
tors
fo
r liq
uid
phas
e se
para
tion
of e
nant
iom
ers
Tbili
si St
ate U
nive
rsity
Geor
gia
Oral
109
:00 –
09:20
Didi
er T
hiéb
aut
Eval
uatio
n of
alte
rnat
ive
solv
ents
in n
orm
al
phas
e liq
uid
and
supe
rcrit
ical
flui
d ch
rom
atog
raph
y fo
r lip
id cl
asse
s ana
lysi
sES
PCI P
aris
– CNR
S – P
SL R
esea
rch
Unive
rsity
Franc
eIn
vite
d Or
al
Raw
i Ram
auta
rRe
solv
ing
volu
me-
rest
ricte
d m
etab
olom
ics
usin
g sh
eath
less
capi
llary
ele
ctro
phor
esis
-m
ass s
pect
rom
etry
Leide
n Un
ivers
ityTh
e Net
herla
nds
Gerh
ard
Scrib
aCa
pilla
ry e
lect
roph
ores
is
in th
e de
term
inat
ion
of th
e st
ereo
isom
eric
pu
rity
of d
rugs
Fried
rich
Schi
ller U
nive
rsity
Germ
any
Invi
ted
Oral
Oral
209
:20 –
09:40
Abhi
jit Ta
rafd
erMo
delin
g re
tent
ion
beha
vior
und
er so
lven
t gr
adie
nt co
nditi
on in
SFC
Wate
rs Co
rpor
ation
USA
Chris
tian
Neus
üßMa
ss sp
ectr
omet
ric ch
arac
teriz
atio
n of
impu
ritie
s of a
n an
tibod
y se
para
ted
by S
DS-c
apill
ary
siev
ing
elec
trop
hore
sis
usin
g CS
E-CZ
E-MS
Aale
n Un
ivers
ityGe
rman
y
Kenj
i Ham
ase
Thre
e-di
men
sion
al H
PLC
anal
ysis
of a
min
o ac
id e
nant
iom
ers i
n co
mpl
icat
ed re
al w
orld
sa
mpl
esKy
ushu
Uni
vers
ityJa
pan
Oral
309
:40 –
10:00
Char
lene
Mus
cat G
alea
Optim
izatio
n of
tem
pera
ture
and
bac
k-pr
essu
re in
dru
g-im
purit
y pr
ofilin
g by
SFC
: A
resp
onse
surf
ace
desi
gn a
ppro
ach
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Aran
Pau
lus
Capi
llary
ele
ctro
phor
esis
– m
ass
spec
trom
etry
for i
ntac
t mas
s ana
lysi
s of
ant
ibod
ies a
nd a
ntib
ody-
drug
-con
juga
tes
Ther
mo F
isher
Scie
ntifi
cUS
A
Tiva
dar F
arka
sFu
rthe
r stu
dies
on
the
HILI
C ch
arac
ter
of p
olys
acch
arid
e-ba
sed
chira
l sta
tiona
ry
phas
es in
pol
ar o
rgan
ic se
para
tion
mod
ePh
enom
enex
, Inc.
USA
10:00
– 10
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Coffe
e bre
ak sp
onso
red
by
Tues
day,
20
June
10:3
0 – 12
:00 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
6FU
N 6
HYP
6AP
P 6
Nove
l hig
h-effi
cien
t sep
arat
ion
med
iaCh
airs
: And
rew
Alpe
rt, F
rank
Ste
iner
Nano
fluid
ic a
nd m
icro
fluid
ic se
para
tions
–
MSCh
airs
: Rob
ert T
. Ken
nedy
, Pet
er W
illis
Lipi
dom
ics
Chai
rs: G
erha
rd L
iebi
sch,
W
illia
m C
raig
Byr
dwel
lKe
ynot
e10
:30 –
11:00
Mary
Wirt
hPr
otei
n HP
LC w
ith p
olym
er b
onde
d ph
ases
on
silic
aPu
rdue
Uni
vers
ityUS
A
Robe
rt T.
Ken
nedy
HPLC
-MS
anal
ysis
of s
mal
l sam
ples
at h
igh
pres
sure
sUn
ivers
ity of
Mich
igan
USA
Mark
us R
. Wen
kNa
tura
l var
iatio
n of
blo
od p
lasm
a lip
ids
in h
ealth
y As
ian
indi
vidu
als
Natio
nal U
nive
rsity
of S
inga
pore
Singa
pore
Oral
111
:00 –
11:20
Jelle
De
Vos
Micr
oflui
dic c
hip
tech
nolo
gy to
adv
ance
m
ultid
imen
sion
al li
quid
chro
mat
ogra
phy
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Andr
ea G
arga
noOn
line
nano
2DL
C m
eets
Top-
Down
MS:
W
CX-H
ILIC
/a×m
/RPL
C UV
PD-H
RMS
anal
ysis
of
his
tone
pro
teof
orm
sCe
nter
for A
nalyt
ical C
hem
istry
Am
ster
dam
The N
ethe
rland
s
Huw
ei L
iuLi
pido
mic
ana
lysi
s of p
lasm
a in
pat
ient
s wi
th la
cuna
r inf
arct
ion
usin
g no
rmal
-ph
ase/
reve
rsed
-pha
se 2
D LC
-MS/
MSPe
king U
nive
rsity
China
Invi
ted
Oral
Oral
211
:20 –
11:40
Yi C
hen
Long
-ran
ge u
nifo
rm p
hoto
nic c
ryst
als
for h
igh
perf
orm
ance
sepa
ratio
nIn
stitu
te of
Chem
istry,
Chin
ese A
cade
my
of S
cienc
esCh
inaIn
vite
d Or
al
Wim
De
Mals
che
New
deve
lopm
ents
in p
illar
arr
ay co
lum
n te
chno
logy
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Miro
slav
Lís
aLi
pido
mic
ana
lysi
s of b
iolo
gica
l sam
ples
: Co
mpa
rison
of l
iqui
d ch
rom
atog
raph
y, su
perc
ritic
al fl
uid
chro
mat
ogra
phy
and
dire
ct in
fusi
on m
ass s
pect
rom
etry
met
hods
Unive
rsity
of Pa
rdub
iceCz
ech
Repu
blic
Oral
311
:40 –
12:00
Keni
chi N
agas
eTh
erm
ores
pons
ive-
ioni
c blo
ck co
poly
mer
br
ush
mod
ified
stat
iona
ry p
hase
for
ther
mal
ly-m
odul
ated
pro
tein
s sep
arat
ion
Toky
o Wom
en’s
Medic
al U
nive
rsity
Japa
n
Rico
War
ias
Chip
-bas
ed li
quid
chro
mat
ogra
phy
– m
ass
spec
trom
etry
: An
inte
grat
ed to
ol to
stud
y ca
taly
sis a
t the
mic
rosc
ale
Unive
rsity
of Le
ipzig
Germ
any
Mich
ael W
ittin
g Io
n m
obili
ty a
s add
ition
al se
para
tion
dim
ensi
on to
tack
le th
e co
mpl
exity
of
the
Caen
orha
bditi
s ele
gans
lipi
dom
eHe
lmho
ltz Ze
ntru
m M
ünch
enGe
rman
y
12:00
– 14
:00Lu
nch,
Exh
ibiti
on, P
oste
rs, V
endo
r sem
inar
sLu
nch
spon
sore
d by
Shi
mad
zu
Meet
ing
Hall
VSe
ssion
6YO
U 6
Chira
l and
ach
iral s
tatio
nary
pha
ses
Chai
rs: B
ezha
n Ch
ankv
etad
ze,
Alla
Che
rnob
rovk
ina
Tuto
rial
10:30
– 11
:10W
olfg
ang
Lind
ner
Prin
cipl
es o
f ena
ntio
sepa
ratio
ns in
LC:
Stat
e of
the
art,
quo
vadi
sUn
ivers
ity of
Vien
naAu
stria
Shor
t ora
l 111
:10 –
11:22
Ravi
ndra
Heg
ade
Stat
iona
ry p
hase
opt
imize
d se
lect
ivity
ch
iral l
iqui
d ch
rom
atog
raph
y (S
OS-C
LC)
as a
nov
el p
ersp
ectiv
e fo
r the
sepa
ratio
n of
ster
eois
omer
sGh
ent U
nive
rsity
Belg
iumSh
ort o
ral 2
11:22
– 11
:34Ju
dyta
Hej
niak
Flav
anon
es e
nant
iose
para
tion
by LC
-ESI
-MS/
MS a
nd it
s app
licat
ion
Siles
ian U
nive
rsity
of Te
chno
logy
, Fac
ulty
of
Chem
istry
Pola
ndSh
ort o
ral 3
11:34
– 11
:46Ma
gdal
ena
Skoc
zyla
sMu
lti-p
aram
etric
char
acte
rizat
ion
of a
min
o ac
ids-
and
pep
tide-
silic
a st
atio
nary
pha
ses
– a
colu
mn
sele
ctio
n fo
r sep
arat
ion
targ
ets
Nico
laus
Cope
rnicu
s Uni
vers
ityPo
land
Shor
t ora
l 411
:46 –
11:58
Rom
ana
Jaro
sova
Nitr
ogen
-inc
orpo
rate
d te
trah
edra
l am
orph
ous c
arbo
n th
in-fi
lms –
A n
ew
elec
trod
e fo
r the
HPL
C-EC
of b
iolo
gica
l an
d en
viro
nmen
tal a
naly
tes
Mich
igan
Stat
e Uni
vers
ityUS
A
38 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Tues
day,
20
June
14:0
0 – 15
:30 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
7FU
N 7
HYP
7AP
P 7
Elec
trom
igra
tion
tech
niqu
esCh
airs
: Edw
ard
S. Ye
ung,
Eva
Tesa
řová
LC/M
S in
lipi
dom
ics
Chai
rs: M
arku
s R. W
enk,
Huw
ei L
iuAffi
nity
sepa
ratio
nsCh
airs
: Mar
y Wirt
h, K
evin
A. S
chug
Keyn
ote
14:00
– 14
:30Ma
rja-L
iisa
Riek
kola
Capi
llary
ele
ctro
phor
esis
– a
ltern
ativ
e te
chni
que
for b
iose
nsor
s?Un
ivers
ity of
Hel
sinki
Finla
nd
Gerh
ard
Lieb
isch
Rele
vanc
e of
app
ropr
iate
inte
rnal
stan
dard
s fo
r acc
urat
e qu
antifi
catio
n of
lipi
d sp
ecie
s by
LC-M
S/MS
Unive
rsity
Hos
pital
Reg
ensb
urg
Germ
any
Koji
Otsu
kaTh
e us
e of
spec
ific i
nter
actio
ns w
ith
fulle
rene
s in
mic
rosc
ale
liqui
d ph
ase
sepa
ratio
nsKy
oto U
nive
rsity
Japa
n
Oral
114
:30 –
14:50
Václ
av K
ašič
kaAffi
nity
capi
llary
ele
ctro
phor
esis
em
ploy
ed fo
r qua
ntita
tive
char
acte
rizat
ion
of n
onco
vale
nt m
olec
ular
inte
ract
ions
Inst
itute
of O
rgan
ic Ch
emist
ry an
d Bi
oche
mist
ry
of th
e Cze
ch A
cade
my o
f Scie
nces
Czec
h Re
publ
icIn
vite
d Or
al
Mich
el G
uich
arda
ntCh
iral L
C-MS
/ MS
ana
lyse
s of f
ree
and
este
rified
oxy
gena
ted
met
abol
ites d
eriv
ing
from
ara
chid
onic
and
doc
osah
exae
noic
ac
ids i
n br
ains
of r
ats e
xang
uina
ted
or n
otIN
SA Ly
onFra
nce
Davi
d Ha
gePe
rson
alize
d m
edic
ine
base
d on
hig
h-pe
rfor
man
ce a
ffini
ty m
icro
colu
mns
: Dr
ug-p
rote
in b
indi
ng st
udie
s with
mod
ified
pr
otei
ns a
nd cl
inic
al sa
mpl
esUn
ivers
ity of
Neb
rask
aUS
A
Oral
214
:50 –
15:10
Mich
al R
oth
Supe
rcrit
ical
wat
er-t
reat
ed fu
sed
silic
a ca
pilla
ries:
curr
ently
acc
essi
ble
mor
phol
ogie
s and
app
licat
ions
in
ele
ctro
mig
ratio
n se
para
tions
Inst
itute
of A
nalyt
ical C
hem
istry
of
the C
zech
Aca
dem
y of S
cienc
esCz
ech
Repu
blic
Jose
f Cva
čka
Stru
ctur
al ch
arac
teriz
atio
n of
lipi
ds
asso
ciat
ed w
ith th
e fe
tal s
kin
deve
lopm
ent
Inst
itute
of O
rgan
ic Ch
emist
ry an
d Bi
oche
mist
ryCz
ech
Repu
blic
Herm
ann
Wät
zigAffi
nity
capi
llary
ele
ctro
phor
esis
for l
igan
d bi
ndin
g as
says
: Pla
ying
the
ACE
card
Unive
rsity
of B
raun
schw
eigGe
rman
y
Oral
315
:10 –
15:30
Pave
l Dub
ský
Com
pute
r-as
sist
ed m
odel
ling,
opt
imiza
tions
an
d da
ta e
valu
atio
ns in
ele
ctro
phor
esis
Facu
lty of
Scie
nce,
Char
les U
nive
rsity
Czec
h Re
publ
ic
Lina
Zho
u Th
at si
mul
tane
ous a
naly
sis o
f met
abol
ome
and
lipid
ome
base
d on
hea
rt-c
uttin
g tw
o-di
men
sion
al li
quid
chro
mat
ogra
phy-
mas
s sp
ectr
omet
ryDa
lian
Inst
itute
of C
hem
ical P
hysic
s, Ch
ines
e Ac
adem
y of S
cienc
esCh
ina
Andr
eas M
anz
"Lab
on
chip
" – b
iom
imet
ic ch
anne
l ne
twor
ksKI
ST Eu
rope
Germ
any
15:30
– 16
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Coffe
e bre
ak sp
onso
red
by S
him
adzu
Meet
ing
Hall
VSe
ssion
7YO
U 7
Ultr
ahig
h-re
solu
tion
mas
s spe
ctro
met
ryCh
airs
: Jan
Pre
isle
r, An
toní
n Be
dnař
ík
Tuto
rial
14:00
– 14
:40Al
exan
der M
akar
ovTh
eory
and
pra
ctic
e of
Orb
itrap
mas
s sp
ectr
omet
ry
Ther
mo F
isher
Scie
ntifi
cGe
rman
y
Shor
t ora
l 114
:40 –
14:52
Davi
d Pa
ulPh
arm
acok
inet
ics a
nd b
rain
upt
ake
stud
y of
nov
el A
MPA
rece
ptor
ant
agon
ist
pera
mpa
nel i
n Sp
ragu
e Da
wely
rats
usi
ng
a va
lidat
ed U
HPLC
-QTO
F-MS
met
hod
Natio
nal I
nstit
ute o
f Pha
rmac
eutic
al Ed
ucat
ion
and
Rese
arch
NIP
ER-H
yder
abad
India
Shor
t ora
l 214
:52 –
15:04
Piet
er V
ente
rAn
alys
is o
f che
stnu
t tan
nins
by
reve
rsed
ph
ase-
and
hyd
roph
ilic i
nter
actio
n ch
rom
atog
raph
y co
uple
d to
ion
mob
ility
an
d hi
gh re
solu
tion
mas
s spe
ctro
met
ryUn
ivers
ity of
Ste
llenb
osch
Sout
h Af
rica
Shor
t ora
l 315
:04 –
15:16
Nath
aly
Reye
s Gar
ces
Solid
pha
se m
icro
extr
actio
n an
d liq
uid
chro
mat
ogra
phy
coup
led
to h
igh
reso
lutio
n m
ass s
pect
rom
etry
: A p
ower
ful p
latfo
rm
for i
n vi
vo b
rain
met
abol
omic
s stu
dies
Unive
rsity
of W
ater
loo
Cana
daSh
ort o
ral 4
15:16
– 15
:28As
hley
Bog
gsMe
asur
ing
ster
oid
profi
les i
n wh
ale
blub
ber
by li
quid
chro
mat
ogra
phy
tand
em m
ass
spec
trom
etry
Natio
nal I
nstit
ute o
f Sta
ndar
ds an
d Tec
hnol
ogy
USA
39HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Tues
day,
20
June
16:3
0 – 18
:00 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
8FU
N 8
HYP
8AP
P 8
Sepa
ratio
n te
chni
ques
for i
onic
com
poun
dsCh
airs
: Kev
in D
. Wyn
dham
, Mi
chae
l Läm
mer
hofe
r
Supe
rcrit
ical
flui
d ch
rom
atog
raph
y –
MSCh
airs
: Car
olin
e W
est,
Miro
slav
Lís
aGl
ycom
ics a
nd g
lyco
prot
eom
ics –
Ce
lebr
atin
g Mi
loš N
ovot
ný 7
5th b
irthd
ayCh
airs
: Fra
ntiš
ek Fo
ret,
Jana
Kře
nkov
áKe
ynot
e16
:30 –
17:00
Paul
R. H
adda
dMe
thod
dev
elop
men
t in
HILI
C us
ing
quan
titat
ive
stru
ctur
e-re
tent
ion
rela
tions
hips
bas
ed o
n an
alyt
e m
olec
ular
st
ruct
ures
Aust
ralia
n Ce
ntre
for R
esea
rch
on S
epar
ation
Sc
ience
Aust
ralia
Davy
Gui
llarm
eSF
C-MS
: Cur
rent
stat
us a
nd fu
ture
di
rect
ions
Unive
rsity
of G
enev
aSw
itzer
land
Milo
š V. N
ovot
ný
LC a
nd LC
-MS
in se
rvic
e of
ana
lytic
al
glyc
osci
ence
India
na U
nive
rsity
USA
Oral
117
:00 –
17:20
Mire
k Ma
cka
Brea
dboa
rd-t
ype
mod
ular
mic
roflu
idic
sy
stem
as f
ront
-end
for m
icro
solid
pha
se
extr
actio
n on
-lin
e co
uple
d wi
th ca
pilla
ry
ion
chro
mat
ogra
phy
Unive
rsity
of Ta
sman
iaAu
stra
liaIn
vite
d Or
al
Laur
a Ak
bal
Enha
ncin
g io
niza
tion
in su
perc
ritic
al fl
uid
chro
mat
ogra
phy
– el
ectr
ospr
ay m
ass
spec
trom
etry
Unive
rsity
of G
enev
aSw
itzer
land
Andr
as G
uttm
anTe
mpe
ratu
re g
radi
ent c
apill
ary
elec
trop
hore
sis
Unive
rsity
of D
ebre
cen
Hung
ary
Invi
ted
Oral
Oral
217
:20 –
17:40
Sam
Wou
ters
Mini
atur
ized
ion
chro
mat
ogra
phic
pla
tform
in
tegr
atin
g se
para
tion,
supp
ress
ion,
an
d de
tect
ion
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Julie
n Cr
epie
r Hy
phen
atio
n of
supe
rcrit
ical
flui
d ch
rom
atog
raph
y an
d hi
gh re
solu
tion
mas
s sp
ectr
omet
ry fo
r the
char
acte
rizat
ion
of a
fast
pyr
olys
is o
ilIFP
ENFra
nce
Anah
ita E
ckar
dDe
velo
pmen
t of a
rapi
d an
d ro
bust
n-g
lyca
n an
alys
is w
orkfl
ow fo
r bot
h LC
and
CE
plat
form
sTh
erm
oFish
erSc
ientifi
cUS
A
Oral
317
:40 –
18:00
Chris
toph
er P
ohl
New
anio
n ex
chan
ge m
ater
ials
bas
ed
on e
lect
rost
atic
ally
atta
ched
hyp
erbr
anch
ed
cond
ensa
tion
poly
mer
sTh
erm
o Fish
er S
cient
ific
USA
Volo
dym
yr P
auk
Valid
atio
n an
d co
mpa
rison
of u
ltra-
high
per
form
ance
supe
rcrit
ical
flui
d ch
rom
atog
raph
y an
d liq
uid
chro
mat
ogra
phy
met
hods
for a
naly
sis o
f new
des
igne
r dru
gs
in h
uman
urin
ePa
lack
ý Uni
vers
ity O
lom
ouc
Czec
h Re
publ
ic
Jana
Kře
nkov
áHi
gh se
nsiti
ve C
E-MS
ana
lysi
s of p
ositi
vely
ch
arge
d ol
igos
acch
arid
esCz
ech
Acad
emy o
f Scie
nces
Cz
ech
Repu
blic
20:00
– 21
:00Or
gan
Conc
ert i
n th
e Ba
silic
a of
St.
Pete
r and
St.
Paul
Csa
ba H
orvá
th Yo
ung S
cient
ist Aw
ard
final
ists
Meet
ing
Hall
VSe
ssion
8YO
U 8
Elec
trom
igra
tion
tech
niqu
esCh
airs
: Vác
lav
Kaši
čka,
Duš
an B
erek
Tuto
rial
16:30
– 17
:10Ed
war
d S.
Yeun
gCa
pilla
ry e
lect
roph
ores
isIow
a Sta
te U
nive
rsity
USA
Shor
t ora
l 117
:10 –
17:22
Elen
a Fa
rcas
Optim
isat
ion
of a
n el
ectr
opho
retic
app
roac
h fo
r the
scre
enin
g an
d th
e de
velo
pmen
t of
new
ant
ithro
mbo
tic d
rugs
Unive
rsity
of Li
ège
Belg
iumSh
ort o
ral 2
17:22
– 17
:34Ke
vin
Jooß
Two-
dim
ensi
onal
capi
llary
zone
el
ectr
opho
resi
s cou
pled
to m
ass
spec
trom
etry
for t
he ch
arac
teriz
atio
n of
mon
oclo
nal a
ntib
ody
char
ge v
aria
nts
on th
e in
tact
leve
lAa
len
Unive
rsity
of A
pplie
d Sc
ience
sGe
rman
ySh
ort o
ral 3
17:34
– 17
:46Er
zséb
et V
arga
Sing
le-i
som
er cy
clod
extr
in d
eriv
ativ
es
in ch
iral c
apill
ary
elec
trop
hore
sis:
The
pas
t, th
e pr
esen
t and
the
futu
reCy
clola
b KF
T.Hu
ngar
ySh
ort o
ral 4
17:46
– 17
:58Mi
chal
Gre
gus
Capi
llary
ele
ctro
phor
esis
-mas
s sp
ectr
omet
ry a
s a n
ovel
tech
niqu
e in
ana
lysi
s of c
hole
ster
ol a
nd it
s m
etab
olite
sMa
sary
k Uni
vers
ityCz
ech
Repu
blic
40 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Wed
nesd
ay, 2
1 Ju
ne8:
30 –
10:0
0Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
9FU
N 9
HYP
9AP
P 9
Sepa
ratio
n m
echa
nism
s and
stru
ctur
al
effec
tsCh
airs
: Tor
gny
Forn
sted
t, Mi
loš V
. Nov
otný
Biom
arke
r dis
cove
ry in
met
abol
omic
sCh
airs
: Lia
ng L
i, Uw
e Ka
rst
Rece
nt a
dvan
ces i
n (b
io)p
harm
aceu
tical
s I.
Chai
rs: I
an D
. Wils
on, L
ois A
nn B
eave
r
Keyn
ote
08:30
– 09
:00Da
vid
McCa
lley
A st
udy
of th
e an
alys
is o
f aci
dic c
ompo
unds
by
hyd
roph
ilic i
nter
actio
n ch
rom
atog
raph
yUn
ivers
ity of
the W
est o
f Eng
land
Unite
d King
dom
Mich
ael L
ämm
erho
fer
Lipi
dom
ics b
y da
ta-i
ndep
ende
nt a
cqui
sitio
n fo
r clin
ical
ana
lysi
sUn
ivers
ity of
Tueb
inge
nGe
rman
y
Koen
San
dra
Two
dim
ensi
onal
liqu
id ch
rom
atog
raph
y:
From
clon
e se
lect
ion
to d
etai
led
char
acte
rizat
ion
of m
onoc
lona
l ant
ibod
ies
and
antib
ody-
drug
conj
ugat
esRe
sear
ch In
stitu
te fo
r Chr
omat
ogra
phy
Belg
ium
Oral
109
:00 –
09:20
Bret
t Pau
llAn
othe
r 12
mon
ths c
lose
r to
3D p
rinte
d HP
LC co
lum
ns!
Unive
rsity
of Ta
sman
iaAu
stra
lia
Thom
as H
anke
mei
erMe
tabo
lom
ics e
nabl
ing
pers
onal
ized
med
icin
eLe
iden
Unive
rsity
The N
ethe
rland
sIn
vite
d Or
al
Jona
than
Bon
esMa
nufa
ctur
abili
ty a
sses
smen
t of
mon
oclo
nal a
ntib
odie
s usi
ng a
dvan
ced
LC-M
SNa
tiona
l Ins
titut
e for
Biop
roce
ssin
g Res
earc
h an
d Tra
inin
gIre
land
Oral
209
:20 –
09:40
Rob
Hase
lber
gHo
w th
e he
ck to
get
your
idea
l SEC
in
the
mas
s spe
c?! A
stud
y in
to
the
the
elut
ion
and
ioni
zatio
n be
havi
or
of b
iom
acro
mol
ecul
es in
aqu
eous
SEC
-MS
Vrije
Uni
vers
iteit
Amst
erda
mTh
e Net
herla
nds
Geor
gios
The
odor
idis
LC-M
S/MS
bas
ed ta
rget
ed m
etab
olom
ics.
Appl
icat
ion
in b
iom
arke
r dis
cove
ry a
nd
the
char
acte
risat
ion
of b
iolo
gica
l and
oth
er
type
s of s
ampl
esAr
istot
le U
nive
rsity
Thes
salo
niki
Gree
ce
Vale
ntin
a D'A
tri
HILI
C-MS
: A p
ower
ful a
naly
tical
tool
fo
r the
pro
filin
g of
gly
cosy
latio
n pa
ttern
s of b
ioph
arm
aceu
tical
pro
tein
s at
the
mid
dle-
up le
vel
Unive
rsity
of G
enev
aSw
itzer
land
Oral
309
:40 –
10:00
Duša
n Be
rek
Rete
ntio
n m
echa
nism
s in
liqui
d ch
rom
atog
raph
y of
unc
harg
ed sy
nthe
tic
poly
mer
sSl
ovak
Aca
dem
y of S
cienc
esSl
ovak
iaIn
vite
d Or
al
Soph
ie B
ravo
-Vey
rat
High
-thr
ough
put d
iffer
entia
l mob
ility
sp
ectr
omet
ry-m
ass s
pect
rom
etry
fo
r mon
itorin
g ox
idat
ive
stre
ss m
arke
rs
in h
uman
who
le b
lood
Life S
cienc
esSw
itzer
land
Tao
Chen
De-c
onju
gatio
n co
uple
d wi
th LC
-MS
for i
nves
tigat
ing
the
stab
ility
of s
mal
l m
olec
ule
drug
s in
antib
ody-
drug
co
njug
ates
Gene
ntec
h, In
cUS
A
10:00
– 10
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Meet
ing
Hall
VSe
ssion
9YO
U 9
Mono
lithi
c col
umns
Chai
rs: M
ilton
L. L
ee, J
iří U
rban
Tuto
rial
8:30 –
09:10
Fran
tišek
Šve
c Mo
nolit
hic c
olum
ns: W
hy, h
ow,
and
for w
hat?
Beijin
g Uni
vers
ity of
Che
mica
l Tec
hnol
ogy
China
Shor
t ora
l 109
:10 –
09:22
Beat
riz Fr
esco
Macr
osco
pic t
hree
dim
ensi
onal
carb
on
nano
horn
s mon
olith
for (
mic
ro)s
olid
-pha
se
extr
actio
n of
vola
tile
orga
nic c
ompo
unds
Unive
rsity
of C
órdo
baSp
ain
Shor
t ora
l 209
:22 –
09:34
Alex
andr
a Za
tirak
haPr
epar
atio
n an
d an
alyt
ical
app
licat
ion
of n
ovel
ani
on-e
xcha
nger
s for
ion
chro
mat
ogra
phy
with
impr
oved
sele
ctiv
ity
towa
rd o
rgan
ic a
cids
Lom
onos
ov M
osco
w St
ate U
nive
rsity
Russ
ian Fe
dera
tion
Shor
t ora
l 309
:34 –
09:46
Benj
amin
Pet
ers
Varia
tion
of p
aram
eter
s infl
uenc
ing
the
imm
obili
zatio
n of
liga
nds o
nto
epox
y-m
odifi
ed si
lica
mon
olith
sMe
rck
Germ
any
Shor
t ora
l 409
:46 –
09:58
Mart
ina
Kom
endo
váDe
velo
pmen
t of m
onol
ithic
capi
llary
colu
mn
with
an
inte
grat
ed e
lect
roch
emic
al d
etec
tor
for t
he d
eter
min
atio
n of
dop
amin
e in
urin
eUn
ivers
ity of
Pard
ubice
Czec
h Re
publ
ic
41HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Wed
nesd
ay, 2
1 Ju
ne10
:30 –
12:0
0 Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 10
FUN
10HY
P 10
APP
10Or
gani
c pol
ymer
mon
olith
ic a
nd p
artic
ular
m
ater
ials
Chai
rs: F
rant
išek
Šve
c, Sa
m W
oute
rs
MS b
ased
om
ics
Chai
rs: K
arol
y Vek
ey, A
leš S
vato
šRe
cent
adv
ance
s in
(bio
)pha
rmac
eutic
als I
I.Ch
airs
: Guo
wang
Xu,
Miro
slav
Flie
ger
Keyn
ote
10:30
– 11
:00Mi
lton
L. L
eeCa
pilla
ry co
lum
n te
chno
logi
es
for n
ano-
flow
liqui
d ch
rom
atog
raph
yBr
igham
Youn
g Uni
vers
ityUS
A
Marc
os E
berl
in“C
hrom
atog
raph
y-fr
ee” c
hara
cter
izatio
n of
com
plex
mix
ture
s by
mas
s spe
ctro
met
ryUn
ivers
ity of
Cam
pinas
Braz
il
Kelly
Zha
ngMu
ltipl
exed
mLC
-nLC
for c
ompr
ehen
sive
im
purit
y pr
ofilin
g: A
met
hod
deve
lopm
ent
“fre
e” p
latfo
rmGe
nent
ech
USA
Oral
111
:00 –
11:20
Jiří
Urba
nPo
lym
er m
onol
iths i
n th
e an
alys
is
of d
opam
ine
Masa
ryk U
nive
rsity
Czec
h Re
publ
ic
Gund
a Ko
elle
nspe
rger
Sele
ctiv
ity, m
etab
olite
cove
rage
and
an
alyt
ical
thro
ughp
ut –
how
to a
ddre
ss
thes
e co
nflic
ting
goal
s in
LC-M
S ba
sed
met
abol
omic
wor
kflow
s?Un
ivers
ity of
Vien
naAu
stria
Yun
Huan
gLe
vera
ging
chro
mat
ogra
phic
spee
d an
d effi
cien
cy: I
nteg
ratio
n of
ana
lytic
al S
FC
into
pha
rmac
eutic
al a
naly
sis
Pfize
r Wor
ldwi
de R
esea
rch
& De
velo
pmen
tUS
A
Oral
211
:20 –
11:40
José
Man
uel H
erre
ro-M
artín
ezIn
fluen
ce o
f an
osci
llatin
g m
agne
tic fi
eld
on th
e se
para
tion
perf
orm
ance
of h
ybrid
m
onol
ithic
stat
iona
ry p
hase
s for
HPL
CUn
ivers
itat d
e Val
encia
Spain
Stev
en R
ay W
ilson
On-l
ine
appr
oach
es fo
r enh
anci
ng
auto
mat
ion,
robu
stne
ss a
nd se
lect
ivity
in
nan
o liq
uid
chro
mat
ogra
phy-
mas
s sp
ectr
omet
ryUn
ivers
ity of
Oslo
Norw
ay
Ther
ese
Woh
lsch
lage
r Na
tive
mas
s spe
ctro
met
ry fo
r the
reve
latio
n of
hig
hly
com
plex
gly
cosy
latio
n in
bio
phar
mac
eutic
als
Unive
rsity
of S
alzb
urg
Aust
ria
Oral
311
:40 –
12:00
Fréd
eric
k Ma
theu
sePo
ssib
ilitie
s of a
dvan
ced
3D p
rintin
g to
pro
duce
chro
mat
ogra
phic
supp
orts
with
1-
mic
ron
reso
lutio
nVr
ije U
nive
rsite
it Br
usse
lBe
lgium
Gior
gia
La B
arbe
raUH
PLC-
QTOF
/MS
unta
rget
ed m
etab
olic
pr
ofilin
g fo
r the
iden
tifica
tion
of b
lood
and
ur
inar
y bi
omar
kers
afte
r the
cons
umpt
ion
of m
eat a
nd d
airy
pro
duct
sUn
ivers
ity of
Rom
e La S
apien
zaIta
ly
Bala
sz B
obal
yIm
prov
ed ch
rom
atog
raph
ic co
nditi
ons
for t
he ch
arac
teriz
atio
n of
ant
ibod
y-dr
ug
conj
ugat
esUn
ivers
ity of
Gen
eva,
Unive
rsity
of La
usan
neSw
itzer
land
12:00
– 14
:00Lu
nch,
Exh
ibiti
on, P
oste
rs, V
endo
r sem
inar
s
Meet
ing
Hall
VSe
ssion
10YO
U 10
SFC
and
SFC/
MSCh
airs
: Did
ier T
hiéb
aut,
Julie
n Cr
epie
r
Tuto
rial
10:30
– 11
:10Is
abel
le Fr
anco
isSu
perc
ritic
al fl
uid
chro
mat
ogra
phy
(SFC
)Wa
ters
Belg
ium
Shor
t ora
l 111
:10 –
11:22
Mario
sim
one
Zocc
ali
Onlin
e su
perc
ritic
al fl
uid
extr
actio
n-su
perc
ritic
al fl
uid
chro
mat
ogra
phy-
mas
s sp
ectr
omet
ry fo
r car
oten
oids
det
erm
inat
ion
in re
d ha
bane
ro p
eppe
rsCh
rom
aleo
nt sr
lIta
lySh
ort o
ral 2
11:22
– 11
:34Ka
nji N
agai
Deve
lopm
ent o
f nov
el p
oly(
viny
lpyr
idin
e)-
base
d SF
C co
lum
ns a
nd th
eir a
pplic
atio
nsDA
ICEL
Corp
orat
ionJa
pan
Shor
t ora
l 311
:34 –
11:46
Vinc
ent D
esfo
ntai
neIn
fluen
ce o
f sam
ple
inje
ctio
n so
lven
t on
pea
k sh
ape
for t
he a
naly
sis
of p
harm
aceu
tical
com
poun
ds in
SFC
Unive
rsity
of G
enev
aSw
itzer
land
Shor
t ora
l 411
:46 –
11:58
Maria
Kha
likov
aUH
PSFC
/ESI
-MS
lipid
omic
ana
lysi
s of t
issu
es
and
plas
ma
from
kid
ney
canc
er p
atie
nts
Unive
rsity
of Pa
rdub
iceCz
ech
Repu
blic
42 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Wed
nesd
ay, 2
1 Ju
ne14
:00 –
15:3
0 Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 11
FUN
11HY
P 11
APP
11Th
erm
odyn
amic
s and
sepa
ratio
n m
echa
nism
s in
LCCh
airs
: Fab
rice
Gritt
i, Da
vid
McCa
lley
MALD
I in
LC co
uplin
g an
d MS
imag
ing
Chai
rs: G
érar
d Ho
pfga
rtne
r, Ro
bert
Jirá
sko
Food
ana
lysi
sCh
airs
: Ter
ry B
erge
r, Ma
ssim
o Mo
rbid
elli
Keyn
ote
14:00
– 14
:30Pa
vel J
ande
raMa
jor r
ole
of w
ater
in H
PLC
of p
olar
an
alyt
esUn
ivers
ity of
Pard
ubice
Czec
h Re
publ
ic
Ron
M.A.
Hee
ren
Brea
king
bou
ndar
ies i
n m
olec
ular
imag
ing
Maas
trich
t Uni
vers
ityTh
e Net
herla
nds
Paol
a Du
goMu
ltidi
men
sion
al te
chni
ques
fo
r the
ana
lysi
s of f
ood
prod
ucts
Unive
rsity
of M
essin
aIta
ly
Oral
114
:30 –
14:50
Torg
ny Fo
rnst
edt
A de
eper
look
at h
ow p
ress
ure
affec
ts
the
rete
ntio
n m
echa
nism
in re
vers
ed-p
hase
liq
uid
chro
mat
ogra
phy
Karls
tad
Unive
rsity
Swed
enIn
vite
d Or
al
Jan
Prei
sler
Coup
ling
of se
para
tion
tech
niqu
es
and
deso
rptio
n m
ass s
pect
rom
etry
Masa
ryk U
nive
rsity
Czec
h Re
publ
icIn
vite
d Or
al
Petr
Bed
nář
Stud
y of
seed
coat
com
posi
tion
in re
latio
n to
dor
man
cy a
nd d
omes
ticat
ion
– ut
iliza
tion
of li
quid
chro
mat
ogra
phy
and
mas
s sp
ectr
omet
ryPa
lack
ý Uni
vers
ity O
lom
ouc
Czec
h Re
publ
ic
Oral
214
:50 –
15:10
Oleg
Kro
khin
Pept
ide
rete
ntio
n tim
e pr
edic
tion
in R
PLC
and
HILI
C: P
rote
omic
tech
niqu
es h
elp
to d
isco
ver h
idde
n se
cond
ary
stru
ctur
e eff
ects
Unive
rsity
of M
anito
baCa
nada
Aleš
Sva
toš
Mass
-spe
ctro
met
ric-i
mag
ing
of li
ving
cells
: Ch
alle
nges
, sol
utio
ns, a
nd p
ersp
ectiv
eMa
x Pla
nck I
nstit
ute o
f Mol
ecul
ar P
hysio
logy
Germ
any
Invi
ted
Oral
Nico
la M
arch
etti
Insi
ghts
into
stru
ctur
e-bi
oacc
essi
bilit
y re
latio
nshi
ps o
f pol
yphe
nols
in re
d ch
icor
y by
HPL
C-MS
/MS
Unive
rsity
of Fe
rrara
Italy
Oral
315
:10 –
15:30
Davi
d Be
llIn
vest
igat
ions
of e
quili
brat
ion
dyna
mic
s in
hyd
roph
ilic i
nter
actio
n liq
uid
chro
mat
ogra
phy
(HIL
IC):
Towa
rd a
bet
ter
unde
rsta
ndin
g of
rete
ntio
n m
echa
nism
sMi
llipo
reSig
ma/
Supe
lcoUS
A
Bram
Hei
jsMu
ltim
odal
mas
s spe
ctro
met
ry im
agin
g an
alys
is o
f N-l
inke
d gl
ycan
s and
pro
tein
s fr
om a
sing
le ti
ssue
sect
ion
Leide
n Un
ivers
ity M
edica
l Cen
ter
The N
ethe
rland
s
Ricc
ardo
Zen
ezin
i Chi
ozzi
Disc
over
y of
bio
activ
e pe
ptid
es fr
om
caul
iflow
er (B
rass
ica
oler
acea
) was
te
prot
ein
usin
g a
scal
ed u
p ch
rom
atog
raph
ic
appr
oach
Unive
rsity
of R
ome L
a Sap
ienza
Italy
15:30
– 16
:30Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Meet
ing
Hall
VSe
ssion
11YO
U 11
Phar
mac
eutic
al a
naly
sis
Chai
rs: K
oen
Sand
ra, T
here
se W
ohls
chla
ger
Tuto
rial
14:00
– 14
:40Lo
is A
nn B
eave
rBi
osim
ilars
evo
lutio
n an
d de
man
ds
on a
naly
tical
scie
ntis
tsLA
B En
terp
rises
USA
Shor
t ora
l 114
:40 –
14:52
Lai-
Sheu
ng C
hoi
Meta
bolic
stud
y of
met
hyls
tenb
olon
e in
hor
ses
The H
ong K
ong J
ocke
y Clu
bHo
ng K
ong
Shor
t ora
l 214
:52 –
15:04
Anita
Ayr
eAn
alyt
ical
qua
lity
by d
esig
n-a
met
hodi
cal
appr
oach
for t
he q
uant
itativ
e es
timat
ion
of te
riflun
omid
e fr
om h
uman
pla
sma
Dr. L
. H. H
irana
ndan
i Col
lege
of P
harm
acy
India
Shor
t ora
l 315
:04 –
15:16
Elis
e Le
mas
son
Expl
orin
g m
ixed
-mod
e HP
LC
as a
n al
tern
ativ
e to
reve
rsed
pha
se H
PLC
for i
mpu
rity
profi
ling
of d
rug
cand
idat
esIC
OAFra
nce
Shor
t ora
l 415
:16 –
15:28
Nile
sh J
oshi
A no
rmal
pha
se ch
iral H
PLC
met
hod
for t
he se
para
tion
of e
ight
isom
ers o
f cor
e +
ome
Syng
ene A
mge
n Re
sear
ch Ce
nter
India
43HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Wed
nesd
ay, 2
1 Ju
ne16
:30 –
18:0
0 Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 12
FUN
12HY
P 12
APP
12Ad
vanc
es in
stat
iona
ry p
hase
sCh
airs
: Joe
Pes
ek, Y
i Che
nQu
antit
atio
n in
LC/M
SCh
airs
: Chr
istia
n G.
Hub
er, J
ean-
Luc V
euth
eyNa
tura
l pro
duct
sCh
airs
: And
re d
e Vi
llier
s, Jo
hn Ya
tes
Keyn
ote
16:30
– 17
:00Fr
ance
sco
Gasp
arrin
iOn
the
use
of th
e su
b-2µ
m ch
iral s
tatio
nary
ph
ases
in e
nant
iose
lect
ive
ultr
a-hi
gh
perf
orm
ance
chro
mat
ogra
phy
(UHP
LC/
UHPS
FC)
Unive
rsity
of R
ome L
a Sap
ienza
Italy
Karo
ly V
ekey
Quan
titat
ion
in LC
-MS:
From
acc
urat
e to
app
roxi
mat
eHu
ngar
ian A
cade
my o
f Scie
nces
Hung
ary
Terr
y Be
rger
Supe
rcrit
ical
flui
d ch
rom
atog
raph
y (S
FC)
profi
ling
of h
ops b
itter
ing
acid
s and
de
rivat
ives
usi
ng ch
iral c
olum
nsSF
C Sol
ution
s Inc
.US
A
Oral
117
:00 –
17:20
Tere
nce
Hetz
el
Char
acte
rizat
ion
of p
eak
capa
city
of
mic
robo
re li
quid
chro
mat
ogra
phy
colu
mns
usi
ng g
radi
ent k
inet
ic p
lots
Inst
itute
of En
ergy
and
Envir
onm
enta
l Tec
hnol
ogy
Germ
any
Kevi
n A.
Sch
ugFu
rthe
r dev
elop
men
t of l
iqui
d ch
rom
atog
raph
y –
trip
le q
uadr
upol
e –
mas
s sp
ectr
omet
ry fo
r top
-dow
n in
tact
pro
tein
se
para
tion
and
quan
titat
ion
The U
nive
rsity
of Te
xas a
t Arli
ngto
nUS
AIn
vite
d Or
al
Erw
in R
osen
berg
Char
acte
rizat
ion
of sa
ffron
mar
ker-
an
d ar
oma
com
poun
ds
by o
ne- a
nd co
mpr
ehen
sive
tw
o-di
men
sion
al H
PLC-
IT-TO
F-MS
ana
lysi
sVie
nna U
nive
rsity
of Te
chno
logy
Aust
ria
Oral
217
:20 –
17:40
Suha
s Naw
ada
3D p
rinte
d ce
llula
r aut
omat
a as
opt
imize
d st
atio
nary
pha
se g
eom
etrie
sUn
ivers
ity of
Cant
erbu
ryNe
w Ze
alan
d
Eva
Tyte
ca
UHPL
C-ES
I-MS
/MS
quan
titat
ion
of n
atur
al
estr
ogen
s in
aque
ous m
atric
es a
s pyr
idin
e-3-
sulfo
nyl d
eriv
ativ
esUn
ivers
ité d
e Lièg
eBe
lgium
Karin
e Fa
ure
Com
preh
ensi
ve tw
o-di
men
sion
al
cent
rifug
al p
artit
ion
chro
mat
ogra
phy-
liq
uid
chro
mat
ogra
phy
(CPC
x LC
): Pr
ovid
ing
prep
arat
ive
sepa
ratio
n fo
r com
plex
pla
nt
extr
acts
CNRS
Uni
vers
ité Ly
on 1
Franc
eOr
al 3
17:40
– 18
:00Ta
-Che
n W
eiSy
nthe
sis o
f sup
erfic
ially
por
ous m
onol
iths
with
ord
ered
, elo
ngat
ed m
esop
orou
s ch
anne
ls n
orm
al to
the
surf
ace
Agile
nt Te
chno
logie
sUS
A
Alex
ande
r Sch
riew
erAn
alys
is o
f coe
nzym
e A
deriv
ates
in b
reas
t ca
ncer
cells
by
mea
ns o
f onl
ine
SPE-
HILI
C-ES
I-MS
/MS
Unive
rsity
of M
ünst
erGe
rman
y
Mary
se V
ande
rpla
nck
Chro
mat
ogra
phic
ana
lysi
s of a
lkal
oids
in
Aco
nitu
m p
olle
n: To
ward
s new
insi
ghts
in
pla
nt p
rote
ctio
n m
echa
nism
sUn
ivers
ity of
Lièg
e – G
embl
oux A
gro-
Bio-
Tech
Belg
ium
19:00
– 23
:00Ga
la d
inne
r, Žo
fín P
alac
e
Csa
ba H
orvá
th Yo
ung S
cient
ist Aw
ard
final
ists
Meet
ing
Hall
VSe
ssion
12YO
U 12
Scie
ntifi
c writ
ing
& pu
blis
hing
Chai
rs: P
aul H
adda
d, E
mily
Hild
er,
Fran
tišek
Šve
cPa
ul R
. Had
dad
Aust
ralia
n Ce
ntre
for R
esea
rch
on S
epar
atio
n Sc
ienc
eAu
stra
lia
Emily
Hild
erUn
iver
sity
of S
outh
Aus
tral
iaAu
stra
lia
Fran
tišek
Šve
cBe
ijing
Uni
vers
ity o
f Che
mic
al Te
chno
logy
Chin
a
This
sess
ion w
ill p
rovid
e an
over
view
of th
e pro
cess
es an
d pit
falls
th
at oc
cur i
n th
e diss
emin
ation
of sc
ientifi
c res
earc
h, pa
rticu
larly
pu
blish
ing o
f scie
ntifi
c res
earc
h in
high
qua
lity j
ourn
als,
but
will
also
inclu
de ad
vice o
f the
pre
para
tion
and
pres
enta
tion
of p
oste
rs at
scien
tific m
eetin
gs. T
hese
majo
r com
pone
nts w
ill
be d
iscus
sed:
a det
ailed
analy
sis of
the p
roce
ss fo
r pre
parin
g a m
anus
cript
, sel
ectin
g a jo
urna
l and
subm
ittin
g the
man
uscr
ipt
for r
eview
, res
pond
ing t
o rev
iewer
s’ co
mm
ents
, pre
parin
g a re
vised
m
anus
cript
.
0 – 10
min
Intr
oduc
tion
to th
e pr
esen
ters
and
aim
s of
the
sess
ion
10 –
35 m
inPr
epar
atio
n an
d su
bmis
sion
of a
scie
ntifi
c m
anus
crip
t35
– 50
min
The
revi
ew p
roce
ss a
nd h
ow to
resp
ond
to re
view
ers
50 –
60 m
inPr
epar
atio
n an
d pr
esen
tatio
n of
pos
ters
at
scie
ntifi
c mee
tings
60 –
90 m
inQu
estio
ns a
nd p
anel
dis
cuss
ion
44 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Thur
sday
, 22
June
9:00
– 10
:30
Cong
ress
Hal
lFo
rum
Hal
lMe
etin
g Ha
ll IV
Sess
ion 13
FUN
13HY
P 13
APP
13Da
ta a
naly
sis,
valid
atio
n an
d ch
emom
etric
sCh
airs
: Gab
riel V
ivo-
Truy
ols,
Is
abel
le Fr
anco
is
MS a
pplic
atio
ns fr
om in
orga
nics
to
pha
rmac
eutic
als
Chai
rs: P
aul H
adda
d, R
on M
.A. H
eere
n
Clin
ical
ana
lysi
sCh
airs
: Jos
ef C
vačk
a, M
arco
s Ebe
rlin
Keyn
ote
09:00
– 09
:30Yv
an V
ande
r Hey
den
Chro
mat
ogra
phic
fing
erpr
ints
, exp
erim
enta
l de
sign
s and
mul
tivar
iate
calib
ratio
n to
stud
y in
tere
stin
g co
mpo
unds
in p
lant
s. Ca
se st
udy
indo
le a
lkal
oids
from
psy
chot
ria
nem
oros
aVr
ije U
nive
rsite
it Br
usse
lBe
lgium
Uwe
Kars
tTr
acin
g m
etal
loph
arm
aceu
tical
s in
the
hum
an b
ody
in sp
ace
and
time:
Th
e co
mpl
emen
tary
pow
er o
f sep
arat
ions
an
d im
agin
g te
chni
ques
Unive
rsity
of M
ünst
erGe
rman
y
Ian
D. W
ilson
Digg
ing
deep
er in
to th
e m
etab
olom
e:
Addi
ng io
n m
obili
ty sp
ectr
omet
ry a
s a 3
rd
dim
ensi
on to
bio
mar
ker d
isco
very
and
an
alys
is v
ia U
PLC-
IMS-
MSIm
peria
l Col
lege
Lond
onUn
ited K
ingdo
m
Oral
109
:30 –
09:50
Jan
Urba
nNo
ise
char
acte
rizat
ion
and
peak
de
conv
olut
ion
in li
quid
chro
mat
ogra
phy
– m
ass s
pect
rom
etry
bas
ed o
n pr
obab
ility
th
eory
Unive
rsity
of S
outh
Boh
emia
Czec
h Re
publ
ic
Anto
nín
Bedn
ařík
Th
in-l
ayer
chro
mat
ogra
phy
coup
led
to d
iode
la
ser t
herm
al v
apor
izatio
n IC
P MS
Masa
ryk U
nive
rsity
Czec
h Re
publ
ic
Tom
asz B
acze
kAs
sess
men
t of b
ioge
nic a
min
es a
long
wi
th th
eir p
recu
rsor
s and
met
abol
ites
supp
orte
d by
new
sam
ple
pret
reat
men
t and
se
para
tion
solu
tions
Medic
al U
nive
rsity
of G
dans
kPo
land
Oral
209
:50 –
10:10
Maria
Cel
ia G
arci
a-Al
vare
z-Co
que
Meas
urem
ent o
f res
olut
ion
in co
mpl
ex
chro
mat
ogra
ms a
imed
to o
ptim
ise
the
sepa
ratio
nUn
ivers
ity of
Vale
ncia
Spain
Lisa
Fren
sem
eier
Elec
troc
hem
ical
act
ivat
ion
of p
latin
um
base
d cy
tost
atic
s inv
estig
ated
by
mea
ns
of li
quid
chro
mat
ogra
phy
and
mas
s sp
ectr
omet
ryUn
ivers
ity of
Mün
ster
Germ
any
Mako
to Ts
unod
aOn
e-m
inut
e se
para
tion
of fi
ve
biot
hiol
s usi
ng a
mid
e-m
odifi
ed li
quid
ch
rom
atog
raph
y ch
ipUn
ivers
ity of
Toky
oJa
pan
Oral
310
:10 –
10:30
Ludi
vine
Fere
yQu
ality
-by-
desi
gn, a
pow
erfu
l too
l fo
r ana
lytic
al m
etho
d de
velo
pmen
t in
pha
rmac
eutic
al a
naly
sis:
Ca
se o
f mul
tipro
duct
sepa
ratio
nCh
emBi
oPha
rm te
amFra
nce
Stef
anie
Wer
nisc
hIs
omer
sepa
ratio
ns o
f pla
sma
met
abol
ites
by d
iffer
entia
l mob
ility
coup
led
to ta
ndem
m
ass s
pect
rom
etry
Unive
rsity
of M
ichiga
nUS
A
Davi
d Fr
iede
cký
Unta
rget
ed m
etab
olom
ics i
n di
agno
sing
in
herit
ed m
etab
olic
dis
ease
sPa
lack
ý Uni
vers
ity O
lom
ouc
Czec
h Re
publ
ic
10:30
– 11
:00Co
ffee
brea
k, E
xhib
ition
, Pos
ters
Meet
ing
Hall
VSe
ssion
13YO
U 13
Ultr
ahig
h-pe
rfor
man
ce li
quid
ch
rom
atog
raph
yCh
airs
: Fra
nces
co G
aspa
rrin
i, Li
na Z
hou
Tuto
rial
9:00 –
09:40
Fran
k St
eine
rUn
ders
tand
ing
inst
rum
enta
l par
amet
ers
that
affe
ct m
etho
d tr
ansf
er in
UHP
LC
sepa
ratio
ns (s
ome
are
easi
ly o
verlo
oked
)Th
erm
o Fish
er S
cient
ific
Germ
any
Shor
t ora
l 109
:40 –
09:52
Just
ine
Fere
yEx
plor
atio
n by
UHP
LC-H
RMS
of th
e en
zym
atic
pho
spho
ryla
tion
of p
yrim
idin
e nu
cleo
side
sIC
OAFra
nce
Shor
t ora
l 209
:52 –
10:04
Yabi
n W
enRe
tent
ion
pred
ictio
n in
reve
rsed
pha
se
HPLC
usi
ng q
uant
itativ
e st
ruct
ure-
rete
ntio
n re
latio
nshi
ps a
pplie
d to
the
hydr
opho
bic
subt
ract
ion
mod
elAu
stra
lian
Cent
re fo
r Res
earc
h on
Sep
arat
ion
Scien
ce (A
CROS
S) U
TAS
Aust
ralia
Shor
t ora
l 310
:04 –
10:16
Nazl
i Mer
t Ozu
pek
Artifi
cial
neu
ral n
etwo
rk in
the
pred
ictio
n of
gra
dien
t ret
entio
n tim
es fo
r reb
audi
osid
e A
in li
quid
chro
mat
ogra
phy
Doku
z Eylü
l Uni
vers
ity, G
radu
ate S
choo
l of
Nat
ural
and
Appl
ied S
cienc
esTu
rkey
Shor
t ora
l 410
:16 –
10:28
Kahi
na S
liman
iDe
velo
pmen
t and
val
idat
ion
of a
n an
alyt
ical
resi
dues
met
hod
of th
e Am
inop
ropy
ldod
ecyl
prop
aned
iam
ine
bioc
ide
disi
nfec
tant
in d
airy
pro
duct
s by
LC-M
S/MS
Anse
sFra
nce
45HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Thur
sday
, 22
June
11:0
0 – 12
:30 Co
ngre
ss H
all
Foru
m H
all
Meet
ing
Hall
IVSe
ssion
14FU
N 14
HYP
14AP
P 14
Ultr
a-hi
gh re
solu
tion
sepa
ratio
nsCh
airs
: Dei
rdre
Cab
oote
r, Go
vert
Som
sen
High
-thr
ough
put,
data
pro
cess
ing
and
bioi
nfor
mat
ics
Chai
rs: Y
van
Vand
er H
eyde
n, Ja
n Ur
ban
Envi
ronm
enta
l ana
lysi
sCh
airs
: Mire
k Ma
cka,
Ivan
Mik
šík
Keyn
ote
11:00
– 11
:30Se
bast
iaan
Eel
tink
Adva
ncin
g na
tive
prot
ein
sepa
ratio
ns b
y si
ze
excl
usio
n an
d hy
drop
hobi
c int
erac
tion
chro
mat
ogra
phy
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Gabr
iel V
ivo-
Truy
ols
Baye
sian
met
hods
for d
ata
anal
ysis
in H
PLC:
A
para
digm
shift
Unive
rsity
of A
mst
erda
mTh
e Net
herla
nds
Chris
tian
Klam
pflIn
vest
igat
ions
on
the
met
abol
izatio
n of
non
-ste
roid
al a
nti-
infla
mm
ator
y dr
ugs i
n cr
ess (
Lepi
dium
sativ
um) g
rown
hy
drop
onic
ally
in d
rug
cont
amin
ated
wat
erJo
hann
es K
eple
r-Uni
vers
ityAu
stria
Oral
111
:30 –
11:50
Ken
Broe
ckho
ven
Eluc
idat
ing
the
cont
ribut
ion
of in
ject
ion
and
dete
ctio
n to
dis
pers
ion
in li
quid
ch
rom
atog
raph
y us
ing
light
-ind
uced
flu
ores
cenc
e m
easu
rem
ents
Vrije
Uni
vers
iteit
Brus
sel
Belg
ium
Paw
eł W
iczl
ing
How
to q
uick
ly fi
nd a
des
ired
sepa
ratio
n?
Inte
grat
ion
of in
form
atio
n an
d de
cisi
on-
mak
ing
in ch
rom
atog
raph
yMe
dical
Uni
vers
ity of
Gda
ńsk
Pola
nd
Jose
phin
e Lü
beck
Char
acte
rizat
ion
of fa
st p
yrol
ysis
oils
usi
ng
supe
rcrit
ical
flui
d ch
rom
atog
raph
y –
mas
s sp
ectr
omet
ry a
nd ch
emom
etric
dat
a an
alys
isUn
ivers
ity of
Cope
nhag
enDe
nmar
k
Oral
211
:50 –
12:10
Stef
an L
amot
teHi
gh re
solu
tion
in li
quid
chro
mat
ogra
phy-
th
at’s
what
dre
ams a
re m
ade
ofBA
SF S
EGe
rman
y
Osca
r Nuñ
ezLi
quid
chro
mat
ogra
phy,
mas
s spe
ctro
met
ry
and
chem
omet
rics f
or th
e id
entifi
catio
n of
frau
ds in
ext
ra-v
irgin
oliv
e oi
l au
then
ticat
ion
Unive
rsity
of B
arce
lona
Spain
Jean
-Chr
isto
phe
Garr
igue
sMi
crop
orou
s org
anog
el m
ater
ials
for
sam
ple
prep
arat
ion
and
gree
n SF
C an
d U-
HPLC
sepa
ratio
nsCN
RSFra
nce
Oral
312
:10 –
12:30
Taku
ya K
ubo
New
plat
form
for s
impl
e an
d ra
pid
prot
ein-
base
d affi
nity
reac
tions
Kyot
o Uni
vers
ityJa
pan
Kers
tin Z
awat
zky
Push
ing
the
spee
d lim
it fo
r hig
h th
roug
hput
LC-M
S an
alys
is in
supp
ort
of p
harm
aceu
tical
dev
elop
men
t res
earc
hMe
rck &
Co.,
Inc.
USA
Wol
fgan
g Bu
chbe
rger
Resi
due
anal
ysis
of p
harm
aceu
tical
s in
pla
nts
Joha
nnes
-Kep
ler-U
nive
rsity
Linz
Aust
ria
12:30
– 13
:30Lu
nch
Meet
ing
Hall
VSe
ssion
14YO
U 14
Clin
ical
ana
lysi
sCh
airs
: Pat
San
dra,
Eva
Tyte
ca
Tuto
rial
11:00
– 11
:40Em
ily H
ilder
Sam
ple
prep
arat
ion
for c
hrom
atog
raph
ic
anal
ysis
Unive
rsity
of S
outh
Aus
tralia
Aust
ralia
Shor
t ora
l 111
:40 –
11:52
Joac
him
Nag
ler
Syst
ems f
or d
etec
tion
of m
onoa
min
es
in ti
ssue
s bey
ond
brai
nHe
lmho
ltz Ce
nter
Mun
ichGe
rman
y
Shor
t ora
l 211
:52 –
12:04
Zden
ěk S
páči
lDi
scov
ery
and
quan
tifica
tion
of m
etab
olic
m
arke
rs a
ttrib
uted
to th
e ac
tivity
of
inte
stin
al m
icro
biot
aMa
sary
k Uni
vers
ityCz
ech
Repu
blic
Shor
t ora
l 312
:04 –
11:16
Liga
Prie
cina
Bioa
ctiv
e co
mpo
unds
of s
team
-bla
nche
d an
d di
ffere
ntly
drie
d on
ions
Latv
ia Un
ivers
ity of
Agr
icultu
reLa
tvia
Shor
t ora
l 411
:16 –
11:28
Wan
-Lin
g Li
uDe
term
inat
ion
of p
heno
lic a
cids
usi
ng
activ
ated
carb
on-p
olym
er e
xtra
ctio
n co
lum
nCh
ung Y
uan
Chris
tian
Unive
rsity
Taiw
an
46 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Thur
sday
, 22
June
13:3
0 – 15
:45 Co
ngre
ss H
all
Clos
ing
plen
ary
sess
ion
Chai
rs: M
icha
l Hol
čape
k, Fr
antiš
ek Fo
ret,
Pave
l Jan
dera
13:30
– 13
:40Me
dal c
erem
ony
Meda
ls of
Uni
vers
ity of
Pard
ubice
13:40
– 14
:10Al
bert
o Ca
vazz
ini
Ultr
afas
t chi
ral s
epar
atio
ns o
n m
oder
n ch
iral s
tatio
nary
pha
ses:
Con
side
ratio
ns o
n th
e im
pact
of t
he p
artic
le g
eom
etry
on
the
kine
tic p
erfo
rman
ce o
f the
colu
mn
14:10
– 14
:40No
rman
Dov
ichi
Capi
llary
ele
ctro
phor
esis
as a
tool
for b
otto
m-u
p pr
oteo
mic
s
14:40
– 15
:10Do
o So
o Ch
ung
Sam
ple
prec
once
ntra
tion
tech
niqu
es in
-lin
e co
uple
d wi
th ca
pilla
ry e
lect
roph
ores
is-m
ass s
pect
rom
etry
15:10
– 15
:25In
vita
tions
from
3 fu
ture
chai
rmen
HPLC
2019
Mila
n, HP
LC 20
18 W
ashi
ngto
n, HP
LC 20
17 Je
ju
15:25
– 15
:45Cl
osin
g ce
rem
ony
Chai
rs: A
tilla
Felin
ger,
Gera
rd R
ozin
g, Ji
ří Ur
ban
Csab
a Hor
váth
Youn
g Scie
ntist
Awar
d &
Best
Pos
ter A
ward
15:45
– 16
:45Fa
rewe
ll dr
ink
Csa
ba H
orvá
th Yo
ung S
cient
ist Aw
ard
final
ists
49HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
List of Oral Presentations
Opening Plenary SessionPL1-Su - Current state and future directions in liquid chromatographyG. DesmetVrije Universiteit Brussel, Brussel, Belgium
PL2-Su - Ambient and LC-MS lipidomic profiling of clinical samples - new era in cancer diagnosticsZ. TakatsImerial College London, London, United Kingdom
PL3-Su - The LC toolbox for protein biopharmaceutical characterizationP. SandraResearch Institute for Chromatography, Kortrijk, Belgium
PL4-Su - Searching for life on ocean worlds with liquid phase separation systemsP.A. Willis1, M.F. Mora1, J.S. Creamer1, F. Kehl1, E. Tavares da Costa1, A.J. Ricco2, R.C. Quinn2, N. Bramall31 California Institute of Technology, NASA Jet Propulsion Laboratory, Pasadena, USA; 2 NASA Ames Research Center, Moffett Field, USA; 3 Leiden Measurement Technology, Santa Clara, USA
Closing Plenary SessionPL1-Th - Ultrafast chiral separations on modern chiral stationary phases: Considerations on the impact of the particle geometry on the kinetic performance of the columnA. Cavazzini1, F. Gasparrini2, M. Catani1, O. Ismail21 University of Ferrara, Department of Chemistry and Pharmaceutical Sciences, Ferrara, Italy; 2 La Sapienza University of Rome, Department of Drug Chemistry and Technology, Rome, Italy
PL2-Th - Capillary electrophoresis as a tool for bottom-up proteomicsN. Dovichi1, Z. Zhang2, L. Sun3, O. Krokhin4
1 University of Notre Dame, Notre Dame, USA; 2 University of Notre Dame, Chemistry, Notre Dame, USA; 3 Michigan State University, Chemistry, East Lansing, USA; 4 University of Manitoba, Winnipeg, Canada
PL3-Th - Sample preconcentration techniques in-line coupled with capillary electrophoresis-mass spectrometryD.S. ChungSeoul National University, Department of Chemistry, Seoul, Republic of Korea
Program track Fundamentals (FUN) FUN 1 Characterization of HPLC stationary phases - In memory of Jack KirklandFUN1-KN-Mo - Mass transfer properties of zwitterionic chiral stationary phases A. Felinger1, M. Catani2, A. Cavazzini2, W. Lindner3
1 Department of Analytical and Environmental Chemistry, University of Pécs, Pécs, Hungary; 2 Department of Chemistry and Pharmaceutical Sciences, University of Ferrara, Ferrara, Italy; 3 Department of Analytical Chemistry, University of Vienna, Vienna, Austria
Legend: FUN1-O1-Mo (Scientific session - Presentation number - Presentation day - Su – Sunday, Mo – Monday, Tu – Tuesday, We – Wednesday, Th – Thursday) PL – Plenary Lecture, O – Oral or Invited Oral Presentation, KN – Keynote Lecture, TU – Tutorial Lecture, SO – Short Oral Presentation, P – Poster, SC – Short Course
50 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN1-O1-Mo - Improving biomolecule separations with superficially porous silica particlesB. Boyes, T. Langlois, B. Wagner, S. Schuster, J. DeStefanoAdvanced Materials Technology- Inc., Wilmington, USA
FUN1-O2-Mo - Characterization of HPLC stationary phases: How this can lead to novel and improved chromatographyJ. GlajchMomenta Pharmaceuticals, Analytical Development, MA, USA
FUN1-O3-Mo - Experimental evaluation of microfluidic LC column performance: Straight versus serpentine channelsM. Gilar1, T. McDonald2, F. Gritti21 Waters Corporation, Milford, USA; 2 Waters, R&D, Milford, USA
FUN 2 Multi-dimensional separationsFUN2-KN-Mo - Multi-dimensional liquid chromatography – towards a million peaksP. SchoenmakersUniversity of Amsterdam, Amsterdam, The Netherlands
FUN2-O1-Mo - Size exclusion chromatography with superficially porous particlesM. Schure1, R. Moran2, S. Stephanie2, B. Wagner2, C. Luo2
1 Kroungold Analytical- Inc, Theoretical Separation Science Laboratory, Blue Bell, USA; 2 Advanced Materials Technology, R&D, Wilmington, USA
FUN2-O2-Mo - Extended multi-dimensional liquid-chromatography systems for comprehensive analysis of complex polymeric nanoparticlesB. Pirok1,2, R. Peters1,3, P. Schoenmakers1
1 University of Amsterdam, Analytical Chemistry, Amsterdam, The Netherlands; 2 TI-COAST, Amsterdam, The Netherlands;
3 DSM Coating Resins, Waalwijk, The Netherlands
FUN2-O3-Mo - Pareto-optimisation of HILIC×RP-LC separations: Experimental verification and application to phenolic analysisA. de Villiers, M. Muller, A. TredouxStellenbosch University, Chemistry and Polymer Science, Stellenbosch, South Africa
FUN 3 Mechanisms of mass transport phenomenaFUN3-KN-Mo - Combining solvent and non-uniform temperature gradients to improve peak capacity in microfluidic separationsF. Gritti, M. Fogwill, M. Gilar, J. Michienzi, D. SatputeWaters Corporation, Milford, USA
FUN3-O1-Mo - Experimental methodologies for the assessment of individual mass transfer phenomena revisitedD. Cabooter1, H. Song1, D. Sadriaj1, K. Broeckhoven2, G. Desmet2
1 University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium; 2 Free University of Brussels, Department of Chemical Engineering, Brussels, Belgium
FUN3-O2-Mo - System band broadening and its impact in modern size-exclusion chromatography of proteinsS. Fekete, A. Goyon, J.L. Veuthey, D. GuillarmeUniversity of Geneva, Geneva, Switzerland
FUN3-O3-Mo - Surface diffusion of aromatic hydrocarbon analytes in reversed-phase liquid chromatographyJ. Rybka1, A. Höltzel1, A. Seidel-Morgenstern2, U. Tallarek1
1 Philipps-Universität Marburg, Chemistry, Marburg, Germany; 2 Max-Planck-Institut für Dynamik komplexer technischer Systeme, Magdeburg, Germany
51HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN 4 Stationary phases based on inorganic supportsFUN4-KN-Mo - Aqueous normal phase chromatography: The reliable and rugged method for polar compound analysisJ. Pesek, M. MatyskaSan Jose State University, Chemistry, San Jose, USA
FUN4-O1-Mo - Enhancing peak capacity in temperature responsive liquid chromatographyF. Lynen, M. BaertGhent University, Organic and Macromolecular Chemistry, Ghent, Belgium
FUN4-O2-Mo - Revealing the trends in selectivity changes altering the functional layer of novel HILIC stationary phasesA. Chernobrovkina, A. Zatirakha, Y. Sedov, Y. Yandukin, I. Kovalenko, A. Smolenkov, O. ShpigunLomonosov Moscow State University, Chemistry Department, Moscow, Russian Federation
FUN4-O3-Mo - Porous silica layers open tubular multi-channel capillaries as micro analytical platforms for separation and extractionE. Sanz Rodriguez1,2, S.C. Lam1,2, P. Smejkal1, P.R. Haddad1,2, B. Paull1,2
1 University of Tasmania, Australian Centre for Research on Separation Science, Sandy Bay- Hobart, Australia; 2 ARC Training Centre for Portable Analytical Separation Technologies ASTech, School of Physical Sciences- University of Tasmania, Hobart, Australia
FUN 5 Supercritical fluid chromatographyFUN5-KN-Tu - Ions and SFC: An improbable match?C. West, A. Raimbault, E. LemassonUniversité d'Orléans, Orléans, France
FUN5-O1-Tu - Evaluation of alternative solvents in normal phase liquid and supercritical fluid chromatography for lipid classes analysisD. Thiébaut1, N. Prache2, S. Abreu2, P. Chaminade2, J. Vial31 ESPCI Paris - CNRS - PSL Research University, LSABM, PARIS, France; 2 Faculty of Pharmacy, LipSys², Chatenay Malabry, France;
3 ESPCI Paris - PSL Research University, LSABM, PARIS, France
FUN5-O2-Tu - Modeling retention behavior under solvent gradient condition in SFCA. Tarafder, J. HillWaters Corporation, Core Research, Milford, USA
FUN5-O3-Tu - Optimization of temperature and back-pressure in drug-impurity profiling by SFC: A response surface design approachC. Muscat Galea1, D. Didion2, D. Clicq2, D. Mangelings1, Y. Vander Heyden1
1 Vrije Universiteit Brussel, Department of Analytical Chemistry and Pharmaceutical Technology, Brussels, Belgium; 2 UCB Pharma, Department of Analytical Development, Braine l'Alleud, Belgium
FUN 6 Novel high-efficient separation mediaFUN6-KN-Tu - Protein HPLC with polymer bonded phases on silicaM. Wirth, J. Yasosky, J. Biechele-Speziale, R. JacobsonPurdue University, West Lafayette, USA
FUN6-O1-Tu - Microfluidic chip technology to advance multidimensional liquid chromatographyJ. De Vos, G. Desmet, S. EeltinkVrije Universiteit Brussel, Chemical Engineering, Brussels, Belgium
FUN6-O2-Tu - Long-range uniform photonic crystals for high performance separationY. ChenInstitute of Chemistry- Chinese Academy of Sciences, CAS Key Lab Anal Chem for Living Biosystems, Beijing, China
52 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN6-O3-Tu - Thermoresponsive-ionic block copolymer brush modified stationary phase for thermally-modulated proteins separationK. Nagase1, J. Kobayashi1, A. Kikuchi2, Y. Akiyama1, H. Kanazawa3, T. Okano1
1 Tokyo Women's Medical University, Institute of Advanced Biomedical Engineering and Science, Tokyo, Japan; 2 Tokyo University of Science, Department of Materials Science and Technology, Tokyo, Japan; 3 Keio University, Faculty of Pharmacy, Tokyo, Japan
FUN 7 Electromigration techniquesFUN7-KN-Tu - Capillary electrophoresis - alternative technique for biosensors?M.L. Riekkola1, E. Multia1, J. Witos1, K. Lipponen1, J. Samuelsson2, T. Fornstedt2, P. Forssén2, K. Öörni3, M. Jauhiainen4
1 University of Helsinki, Department of Chemistry, Helsinki, Finland; 2 Karlstad University, Department of Engineering and Chemical Sciences, Karlstad, Sweden; 3 Wihuri Research Institute, Helsinki, Finland; 4 National Institute for Health and Welfare, Genomics and Biomarkers Unit, Helsinki, Finland
FUN7-O1-Tu - Affinity capillary electrophoresis employed for quantitative characterization of noncovalent molecular interactionsV. Kašička, M. Ruzicka, D. Koval, J. Vavra, P. Reyes-Gutierrez, F. TeplyInstitute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Praha 6, Czech Republic
FUN7-O2-Tu - Supercritical water-treated fused silica capillaries: Currently accessible morphologies and applications in electromigration separationsP. Karásek, M. Horká, K. Šlais, J. Planeta, M. RothInstitute of Analytical Chemistry of the Czech Academy of Sciences, Department of Fluid Phase Separations, Brno, Czech Republic
FUN7-O3-Tu - Computer-assisted modelling, optimizations and data evaluations in electrophoresisP. DubskýFaculty of Science - Charles University, The group of Electrophoretic and Chromatographic separation Methods - Department of Physical and Macromolecular Chemistry, Prague, Czech Republic
FUN 8 Separation techniques for ionic compoundsFUN8-KN-Tu - Method development in HILIC using quantitative structure-retention relationships based on analyte molecular structuresP.R. Haddad1, M. Taraji1, R. Amos1, M. Talebi1, R. Szucs2, C. Pohl3, J. Dolan4
1 University of Tasmania, Australian Centre for Research on Separation Science, Sandy Bay, Australia; 2 Pfizer Global Research and Development, Analytical R&D, Kent, United Kingdom; 3 Thermo Fisher Scientific, Sunnyvale, USA; 4 LC Resources, McMinnville, USA
FUN8-O1-Tu - Breadboard-type modular microfluidic system as front-end for micro solid phase extraction on-line coupled with capillary ion chromatographyC. Malasuk1,2,3, Y. Li1, P.N. Nesterenko1, K. Uraisin2,3, M. Macka1
1 University of Tasmania ACROSS & School of Chemistry, Hobart, Australia; 2 Mahidol University, Department of Chemistry and Center of Excellence for Innovation in Chemistry, Bangkok, Thailand; 3 Flow Innovation-Research for Science and Technology Laboratories Firstlabs, Bangkok, Thailand
FUN8-O2-Tu - Miniaturized ion chromatographic platform integrating separation, suppression, and detectionS. Wouters1, J.L. Tison2, S. Eeltink1
1 Vrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium; 2 Université Libre de Bruxelles, Laboratoire de Glaciologie, Brussels, Belgium
FUN8-O3-Tu - New anion exchange materials based on electrostatically attached hyperbranched condensation polymersC. PohlThermo Fisher Scientific, R&D, Sunnyvale, USA
53HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN 9 Separation mechanisms and structural effectsFUN9-KN-We - A study of the analysis of acidic compounds by hydrophilic interaction chromatographyD. McCalleyUniversity of the West of England, United Kingdom
FUN9-O1-We - Another 12 months closer to 3D printed HPLC columns!V. Gupta, N. Macdonald, S. Currivan, P. Nesterenko, B. PaullUniversity of Tasmania, ACROSS- School of Physical Sciences, Hobart, Australia
FUN9-O2-We - How the heck to get your ideal SEC in the mass spec?! A study into the the elution and ionization behavior of biomacromolecules in aqueous SEC-MSR. Haselberg1, I. Ventouri1, D. Malheiro1, J. Jordens2, S. Kok2, M. Honing2, G. Somsen1
1 Vrije Universiteit Amsterdam, Division of BioAnalytical Chemistry, Amsterdam, The Netherlands; 2 DSM Resolve, Geleen, The Netherlands
FUN9-O3-We - Retention mechanisms in liquid chromatography of uncharged synthetic polymersD. BerekPolymer Institute, Slovak Academy of Sciences, Slovakia
FUN 10 Organic polymer monolithic and particular materialsFUN10-KN-We - Capillary column technologies for nano-flow liquid chromatographyM.L. Lee, X. Xie, L. Tolley, P. Farnsworth, H.D. TolleyBrigham Young University, Provo, USA
FUN10-O1-We - Polymer monoliths in the analysis of dopamineJ. Urban1,2, S. Janků2, M. Komendová2, R. Metelka2
1 Masaryk University, Department of Chemistry, Brno, Czech Republic; 2 University of Pardubice, Department of Analytical Chemistry- Faculty of Chemical Technology, Pardubice, Czech Republic
FUN10-O2-We - Influence of an oscillating magnetic field on the separation performance of hybrid monolithic stationary phases for HPLCE.J. Carrasco-Correa, V. Dalgo-Flores, G. Ramis-Ramos, E.F. Simó-Alfonso, J.M. Herrero-MartínezUniversitat de Valencia, Analytical Chemistry, Burjassot, Spain
FUN10-O3-We - Possibilities of advanced 3D printing to produce chromatographic supports with 1-micron resolutionF. Matheuse1, Y. Vanderheyden1, K. Vanmol2, J. Van Erps2, W. De Malsche1, H. Ottevaere2, G. Desmet1
1 Vrije Universiteit Brussel, Chemical Engineering, Brussels, Belgium; 2 Vrije Universiteit Brussel, Applied Physics and Photonics, Brussels, Belgium
FUN 11 Thermodynamics and separation mechanisms in LCFUN11-KN-We - Major role of water in HPLC of polar analytesP. Jandera, T. Hájek, P. Janás, J. UrbanUniversity of Pardubice, Pardubice, Czech Republic
FUN11-O1-We - A deeper look at how pressure affects the retention mechanism in reversed-phase liquid chromatographyT. Fornstedt1, D. Åsberg2, S. Jörgen3, M. Leśko4, M. Chutkowski4, K. Krzysztof4
1 Karlstad University, Karlstad, Sweden; 2 Department of Engineering and Chemical Sciences- Karlstad University, Uppsala, Sweden; 3 Department of Engineering and Chemical Sciences- Karlstad University, Karlstad, Sweden; 4 Department of Chemical and Process Engineering- Rzeszów University of Technology, Rzeszów, Poland
FUN11-O2-We - Peptide retention time prediction in RPLC and HILIC: proteomic techniques help to discover hidden secondary structure effectsO. Krokhin, V. SpicerUniversity of Manitoba, Internal Medicine, Winnipeg, Canada
54 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN11-O3-We - Investigations of equilibration dynamics in hydrophilic interaction liquid chromatography (HILIC): Toward a better understanding of retention mechanismsD. Bell, D. ShollenbergerMilliporeSigma/Supelco, Research and Development, Bellefonte, USA
FUN 12 Advances in stationary phasesFUN12-KN-We - On the use of the sub-2µm chiral stationary phases in enantioselective ultra-high performance chromatography (UHPLC/UHPSFC)F. GasparriniUniversity of Rome la Sapienza, Dip. di Chimica e Tecnologie del Farmaco, Roma, Italy
FUN12-O1-We - Characterization of peak capacity of microbore liquid chromatography columns using gradient kinetic plotsT. Hetzel1,2, C. Blaesing1, M. Jaeger3, T. Teutenberg1, T.C. Schmidt2
1 Institute of Energy and Environmental Technology, Research analysis, Duisburg, Germany; 2 University of Duisburg-Essen, Instrumental Analytical Chemistry, Essen, Germany; 3 Niederrhein University of Applied Science, Krefeld, Germany
FUN12-O2-We - 3D printed cellular automata as optimized stationary phase geometriesS. Nawada1, S. Dimartino2, F. Conan1, P. Schoenmakers3
1 University of Canterbury, Chemical and Process Engineering, Christchurch, New Zealand; 2 The University of Edinburgh, Institute for Bioengineering- School of Engineering, Edinburgh U.K., United Kingdom; 3 Universiteit van Amsterdam, HIMS- Faculteit der Natuurwetenschappen, Amsterdam, The Netherlands
FUN12-O3-We - Synthesis of superficially porous monoliths with ordered, elongated mesoporous channels normal to the surfaceT.C. Wei, K. JiangAgilent Technologies, Wilmington, USA
FUN 13 Data analysis, validation and chemometricsFUN13-KN-Th - Chromatographic fingerprints, experimental designs and multivariate calibration to study interesting compounds in plants. Case study indole alkaloids from psychotria nemorosaY. Vander Heyden1, L.C. Klein-Junior1, J. Viaene1, A.T. Henriques2
1 Vrije Universiteit Brussel, Brussels, Belgium; 2 UFRGS Porto Alegre, Porto Alegre- Rio Grande do Sul, Brazil
FUN13-O1-Th - Noise characterization and peak deconvolution in Liquid chromatography – Mass spectrometry based on probability theoryJ. Urban, P. Soucek, D. StysUniversity of South Bohemia, Institute of Complex Systems FFPW, Nove Hrady, Czech Republic
FUN13-O2-Th - Measurement of resolution in complex chromatograms aimed to optimise the separationM.C. Garcia-Alvarez-Coque, J.A. Navarro-Huerta, T. Alvarez-Segura, J.R. Torres-LapasioUniversity of Valencia, Analytical Chemistry, Burjassot Valencia, Spain
FUN13-O3-Th - Quality-by-design, a powerful tool for analytical method development in pharmaceutical analysis: Case of multiproduct separationL. Ferey1, A. Raimbault1, I. Rivals2, K. Gaudin1
1 ChemBioPharm team, ARNA Laboratory, Bordeaux University, Bordeaux, France; 2 Equipe de Statistique Appliquée, ESPCI Paris- PSL Research University, Paris, France
FUN 14 Ultra-high resolution separationsFUN14-KN-Th - Advancing native protein separations by size exclusion and hydrophobic interaction chromatographyS. EeltinkVrije Universiteit Brussel, Brussels, Belgium
FUN14-O1-Th - Elucidating the contribution of injection and detection to dispersion in liquid chromatography using light-induced fluorescence measurementsK. Broeckhoven, K. Vanderlinden, S. Deridder, G. DesmetVrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium
55HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN14-O2-Th - High resolution in liquid chromatography- that’s what dreams are made ofS. LamotteBASF SE, Competence Center Analytics, Ludwigshafen, Germany
FUN14-O3-Th - New platform for simple and rapid protein-based affinity reactionsT. Kubo1, K. Kubota1,2, N. Nishimura1, T. Tanigawa1,3, T. Naito1, K. Otsuka1
1 Kyoto University, Graduate School of Engineering, Kyoto, Japan; 2 Daiichi Sankyo Co.- Ltd., Hiratsuka, Japan; 3 Chemco Scientific Co., Takatsuki, Japan
Program track Hyphenations (HYP)HYP 1 Ion mobility in LC/MSHYP1-KN-Mo - Differential mobility spectrometry - mass spectrometry as an orthogonal separation dimension for omicsG. HopfgartnerUniversity of Geneva, Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, Genève, Switzerland
HYP1-O1-Mo - LC+LC- and GC+GC-IM-qTOF-MS as a potential tool in non-target analysisO. Schmitz, J. Klein, L. Gan, C. LipokUniversity of Duisburg-Essen, Applied Analytical Chemistry, Essen, Germany
HYP1-O2-Mo - Using IMS-MS combined with size-exclusion chromatography and differential hydrogen–deuterium exchange for semi-automated screen of global protein conformational changes in solutionA. Makarov, N. Pierson, C. Strulson, Y. Mao, B. MaoMerck Sharp & Dohme Corp., Process Research & Development, Rahway, USA
HYP1-O3-Mo - Comprehensive separation and analysis of nonionic surfactants by ultra-high performance supercritical fluid chromatography combined with ion mobility spectrometry-mass spectrometryQ. Ma1, Y. Zhang2, H. Bai1, Z. Du2
Chinese Academy of Inspection and Quarantine, Beijing, China; 2 Beijing University of Chemical Technology, Beijing, China
HYP 2 Ion suppression and matrix-effects in separation – MSHYP2-KN-Mo - Evaluation of matrix effects in HILIC, RPLC and SFC-MSJ.L. Veuthey, J. Schappler, D. GuillarmeUniversity of Geneva- University of Lausanne, School of Pharmaceutical Sciences, Geneva 4, Switzerland
HYP2-O1-Mo - Development of UHPSFC-MS method for high-throughput analysis of vitamin E isomers and evaluation of matrix effects when using different sample preparation approachesL. Nováková, V. Pilařová, K. PlachkáCharles University- Faculty of Pharmacy, Department of Analytical chemistry, Hradec Králové, Czech Republic
HYP2-O2-Mo - How much separation for LC–MS/MS quantitative bioanalysis?A. Tan, J. FanarasNucro-Technics, Scarborough, Canada
HYP2-O3-Mo - Can HPLC-MS be replaced by direct coupling of SPME to MS? Investigating challenging casesG. Gomez-Rios1, N. Reyes-Garces1, M. Tascon1, J. Poole1, E. Boyaci1, E. Gionfriddo1, T. Vasiljevic1, S. Lendor1, C. Liu2, T. Covey2, J. Pawliszyn1
1 University of Waterloo, Chemistry, Waterloo, Canada; 2 SCIEX, Concord, Canada
HYP 3 Separation – high-resolution MSHYP3-KN-Mo - Orbitrap technology in LC/MS and GC/MS: On the road to high-resolution in every lab A. MakarovThermo Fisher Scientific, Bremen, Germany
56 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP3-O1-Mo - Top–down proteomics of large proteins up to 223 kDa enabled by serial size exclusion chromatography strategyY. GeUniversity of Wisconsin-Madison, Department of Cell and Regenerative Biology and Department of Chemistry, Madison, USA
HYP3-O2-Mo - Highly selective characterization of intact proteoforms by HILIC-MSG. Somsen1, R. Haselberg1, S. Tengattini2, E. Dominguez-Vega1
1 Vrije Universiteit Amsterdam, Division of Bioanalytical Chemistry, Amsterdam, The Netherlands; 2 University of Pavia, Department of Drug Sciences, Pavia, Italy
HYP3-O3-Mo - A generic hybrid LBA-LC-HRMS-based workflow for multiplexed hIgG1 quantification in pre-clinical species directly at the intact protein levelC. Lanshoeft1,2, S. Cianférani2, O. Heudi11 Novartis Pharma AG, DMPK, Basel, Switzerland; 2 University of Strasbourg, IPHC-LSMBO, Strasbourg, France
HYP 4 Multidimensional chromatography and MS couplingHYP4-KN-Mo - Comprehensive two-dimensional liquid chromatography with quadruple parallel mass spectrometry, LC1MS2 x LC1MS2 = LC2MS4W.C. ByrdwellUSDA- ARS- Beltsville Human Nutrition Research Center, Food Composition & Methods Development Lab, Beltsville, USA
HYP4-O1-Mo - Improving the resolving power and detection sensitivity of two-dimensional liquid chromatography separations of protein digestsD. Stoll1, D. Harmes2, H. Lhotka2, G. Staples3
1 Gustavus Adolphus College, St.Peter, USA; 2 Gustavus Adolphus College, Chemistry, St. Peter, USA; 3 Agilent Technologies, Santa Clara, USA
HYP4-O2-Mo - Implementation of an immobilised-enzyme microfluidic reactor in an integrated multi-dimensional liquid chromatography systemB. Wouters1, I. Dapic2, B. Pirok2, M. Blom3, R. Peters4, G.L. Corthals2, P.J. Schoenmakers2
1 Unversiteit van Amsterdam, Analytical-Chemistry Group, Amsterdam, The Netherlands; 2 Unversiteit van Amsterdam, Van 't Hoff Institute for Molecular Sciences HIMS, Amsterdam, The Netherlands; 3 Micronit Microfluidics, Enschede, The Netherlands; 4 DSM Coating Resins, Waalwijk, The Netherlands
HYP4-O3-Mo - High resolution analysis of linker drugs used in antibody drug conjugates (ADC's) by 2D-LC-MS: Transition of 2D-LC-MS from research to main stream pharmaceutical analysis C.J. Venkatramani1, S.R. Huang2, A.S. Mohammad1, I. Patel1, J. Kay1, L. Wigman1
1 Genentech Inc, SMACQC, South San Francisco, USA; 2 University of Washington, Chemistry, Seattle, USA
HYP 5 Electrodriven separations – MSHYP5-KN-Tu - Measuring endogenous D-amino acids in the brain - from brain regions and individual cells to cellular release -- using CE and LCJ. Sweedler1, A. Patel1, H.C. Tai2, J.W. Checco1, S.S. Rubakhin1
1 University of Illinois at Urbana-Champaign, Department of Chemistry, Urbana, USA; 2 University of Illinois at Urbana-Champaign, Department of Molecular and Integrative Physiology, Urbana, USA
HYP5-O1-Tu - Resolving volume-restricted metabolomics using sheathless capillary electrophoresis-mass spectrometryR. RamautarLeiden University, Leiden Academic Center for Drug Research, Leiden, The Netherlands
HYP5-O2-Tu - Mass spectrometric characterization of impurities of an antibody separated by SDS-capillary sieving electrophoresis using CSE-CZE-MSC. Neusüß, M. CristinaAalen University, Chemistry, Aalen, Germany
HYP5-O3-Tu - Capillary electrophoresis - mass spectrometry for intact mass analysis of antibodies and antibody-drug-conjugatesA. Paulus, C.H. Chen, A. Krupke, S. Houel, M. Wenz, D. Lopez-FerrerThermo Fisher Scientific, LSMS, San Jose, USA
57HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP 6 Nanofluidic and microfluidic separations – MSHYP6-KN-Tu - HPLC-MS analysis of small samples at high pressuresR.T. KennedyUniversity of Michigan, Ann Arbor, USA
HYP6-O1-Tu - Online nano 2DLC meets top-down MS: WCX-HILIC/a×m/RPLC UVPD-HRMS analysis of histone proteoformsA. Gargano1, J. Shaw2, N. Tolič2, P. Schoenmakers3, L. Paša-Tolič2
1 Center for Analytical Chemistry Amsterdam, Analytical Chemistry, Amsterdam, The Netherlands; 2 Pacific Northwest National Laboratory, Earth and Biological Sciences Directorate, Richland, USA; 3 University of Amsterdam, Analytical Chemistry, Amsterdam, The Netherlands
HYP6-O2-Tu - New developments in pillar array column technologyW. De Malsche1, J. Op De Beeck2, K. Van Mol2, B. Claerebout2, N. Van Landuyt2, G. Desmet1
1 Vrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium; 2 PharmaFluidics, Zwijnaarde, Belgium
HYP6-O3-Tu - Chip-based liquid chromatography - mass spectrometry: An integrated tool to study catalysis at the microscaleR. Warias1, J. Heiland1, C. Lotter1, A. Zaghi2, A. Massi2, D. Belder1
1 University of Leipzig, Institute of Analytical Chemistry, Leipzig, Germany; 2 University of Ferrara, Dep. of Chemistry and Pharmaceutical Sciences, Ferrara, Italy
HYP 7 LC/MS in lipidomicsHYP7-KN-Tu - Relevance of appropriate internal standards for accurate quantification of lipid species by LC-MS/MSG. Liebisch, S. KrautbauerUniversity Hospital Regensburg, Regensburg, Germany
HYP7-O1-Tu - Chiral LC-MS / MS analyses of free and esterified oxygenated metabolites deriving from arachidonic and docosahexaenoic acids in brains of rats exanguinated or notM. Guichardant, C. Jouvène, B. Fourmaux, N. Bernoud-Hubac, M. LagardeLaboratoire CarMeN- Univ Lyon- Inserm UMR 1060- Inra UMR 1397- INSA-Lyon- IMBL, Biochemistry, Villeurbanne, France
HYP7-O2-Tu - Structural characterization of lipids associated with the fetal skin developmentJ. Cvačka1,2, V. Vrkoslav1, R. Hanus1, E. Harazim1,2, M. Hoskovec1, A. Kalužíková1,2, R. Míková1,2, J. Rejšek1,2, L. Šubčíková2, T. Čmelíková3, A. Doležal4, R. Plavka4
1 Institute of Organic Chemistry and Biochemistry, Mass Spectrometry, Prague, Czech Republic; 2 Faculty of Science- Charles University in Prague, Department of Analytical Chemistry, Prague, Czech Republic; 3 Joachim Barrande Grammar School, Beroun, Czech Republic; 4 General Faculty Hospital and 1st Faculty of Medicine, Department of Obstetrics and Gynaecology, Prague, Czech Republic
HYP7-O3-Tu - That Simultaneous analysis of metabolome and lipidome based on heart-cutting two-dimensional liquid chromatography-mass spectrometryS. Wang, L. Zhou, X. Shi, G. XuDalian Institute of Chemical Physics- Chinese Academy of Sciences, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian, China
HYP 8 Supercritical fluid chromatography – MSHYP8-KN-Tu - SFC-MS: Current status and future directionsD. Guillarme, V. Desfontaine, J.L. VeutheyUniversity of Geneva, Geneva, Switzerland
HYP8-O1-Tu - Enhancing ionization in supercritical fluid chromatography - electrospray mass spectrometryL. Akbal, G. HopfgartnerUniversity of Geneva, Life Sciences Mass Spectrometry- Department of Inorganic and Analytical Chemistry, Geneva, Switzerland
58 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP8-O2-Tu - Hyphenation of supercritical fluid chromatography and high resolution mass spectrometry for the characterization of a fast pyrolysis oilJ. Crepier1, A. Le Masle1, N. Charon1, F. Albrieux1, S. Heinisch2
1 IFPEN, Physic and analysis, Solaize, France; 2 Institut des Sciences Analytiques, Villeurbanne, France
HYP8-O3-Tu - Validation and comparison of ultra-high performance supercritical fluid chromatography and liquid chromatography methods for analysis of new designer drugs in human urineV. Pauk, L. Borovcová, K. LemrPalacky University in Olomouc, RCPTM Department of Analytical Chemistry, Olomouc, Czech Republic
HYP 9 Biomarker discovery in metabolomicsHYP9-KN-We - Lipidomics by data-independent acquisition for clinical analysisM. Lämmerhofer1, J. Schlotterbeck2, B. Drotleff2
1 University of Tuebingen, Tuebingen, Germany; 2 University of Tuebingen, Institute of Pharmaceutical Sciences, Tuebingen, Germany
HYP9-O1-We - Metabolomics enabling personalized medicineT. HankemeierLeiden University, Leiden, The Netherlands
HYP9-O2-We - LC-MS/MS based targeted metabolomics. Application in biomarker discovery and the characterisation of biological and other types of samplesG. Theodoridis1, H. Gika2
1 Aristotle University Thessaloniki, Chemistry, Thessaloniki, Greece; 2 Aristotle University Thessaloniki, Medicine, Thessaloniki, Greece
HYP9-O3-We - High-throughput differential mobility spectrometry-mass spectrometry for monitoring oxidative stress markers in human whole bloodS. Bravo-Veyrat, H. GérardUniversity of Geneva, Life Sciences Mass Spectrometry- Department of Inorganic and Analytical Chemistry, Genève, Switzerland
HYP 10 MS based omicsHYP10-KN-We - “Chromatography-free” characterization of complex mixtures by mass spectrometryM. EberlinUniversity of Campinas, Campinas, Brazil
HYP10-O1-We - Selectivity, metabolite coverage and analytical throughput - how to address these conflicting goals in LC-MS based metabolomic workflows?G. KoellenspergerUniversity of Vienna, Department of Analytical Chemistry, Vienna, Austria
HYP10-O2-We - On-line approaches for enhancing automation, robustness and selectivity in nano liquid chromatography-mass spectrometryS.R. Wilson, O.K. Brandtzæg, H. Røberg-Larsen, T. Vehus, E. LundanesUniversity of Oslo, Department of Chemistry, Oslo, Norway
HYP10-O3-We - UHPLC-QTOF/MS untargeted metabolic profiling for the identification of blood and urinary biomarkers after the consumption of meat and dairy productsG. La Barbera1, G. Gürdeniz2, M.B.S. Andersen3, L.O. Dragsted2
1 University of Rome La Sapienza, Department of Chemistry, Rome, Italy; 2 University of Copenhagen, Department of Nutrition- Exercise and Sports- Faculty of Science, Copenhagen, Denmark; 3 University of Copenhagen, Department of Food Science- Faculty of Science, Copenhagen, Denmark
HYP 11 MALDI in LC coupling and MS imagingHYP11-KN-We - Breaking boundaries in molecular imagingR.M.A. HeerenMaastricht University, Maastricht, The Netherlands
59HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP11-O1-We - Coupling of separation techniques and desorption mass spectrometryJ. PreislerMasaryk University, Brno, Czech Republic
HYP11-O2-We - Mass-spectrometric-imaging of living cells: Challenges, solutions, and perspective A. SvatošMax Planck Instutue of Molecular Physiology, Dortmund, Germany
HYP11-O3-We - Multimodal mass spectrometry imaging analysis of N-linked glycans and proteins from a single tissue sectionB. Heijs1, S. Holst1, I. Briaire-de Bruijn2, A. de Ru1, P. van Veelen1, R. Drake3, A. Mehta3, W. Mesker4, R. Tollenaar4, J. Bovée2, M. Wuhrer1, L. McDonnell51 Leiden University Medical Center, Center for Proteomics & Metabolomics, Leiden, The Netherlands; 2 Leiden University Medical Center, Department of Pathology, Leiden, The Netherlands; 3 Medical University of South Carolina, Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Charleston, USA; 4 Leiden University Medical Center, Department of Surgery, Leiden, The Netherlands; 5 Fondazione Pisana per la Scienza ONLUS, Pisa, Italy
HYP 12 Quantitation in LC/MSHYP12-KN-We - Quantitation in LC-MS: From accurate to approximate K. VekeyHungarian Academy of Sciences, Budapest, Hungary
HYP12-O1-We - Further development of liquid chromatography - triple quadrupole - mass spectrometry for top-down intact protein separation and quantitationK.A. Schug1, E. Wang1, D. Appulage1, Y. Baghdady1, P. Combe2, J. Smith2, F. Carroll3, T. Kahler3, P. Donato4, P. Dugo4, L. Mondello4
1 U.T. Arlington, Arlington TX, USA; 2 Shimadzu Scientific Instruments Inc., Columbia MD, USA; 3 Restek Corporation, Bellefonte PA, USA; 4 University of Messina, Messina, Italy
HYP12-O2-We - UHPLC-ESI-MS/MS quantitation of natural estrogens in aqueous matrices as pyridine-3-sulfonyl derivativesA. Glineur1, K. Nott2, S. Ronkart2, G. Lognay1, E. Tyteca1, P. Carbonnelle2
1 Université de Liège, Gembloux Agro-Bio Tech, Gembloux, Belgium; 2 Société wallone des eaux, Verviers, Belgium
HYP12-O3-We - Analysis of coenzyme A derivates in breast cancer cells by means of online SPE-HILIC-ESI-MS/MSA. Schriewer, H. HayenUniversity of Münster, Institute of Inorganic and Analytical Chemistry, Münster, Germany
HYP 13 MS applications from inorganics to pharmaceuticalsHYP13-KN-Th - Tracing metallopharmaceuticals in the human body in space and time: The complementary power of separations and imaging techniquesU. KarstUniversity of Muenster, Münster, Germany
HYP13-O1-Th - Thin-layer chromatography coupled to diode laser thermal vaporization ICP MSA. Bednařík1, P. Foltýnová1, V. Kanický1,2, J. Preisler1,2
1 Masaryk University, Department of Chemistry, Brno, Czech Republic; 2 Central European Institute of Technology CEITEC, Brno, Czech Republic
HYP13-O2-Th - Electrochemical activation of platinum based cytostatics investigated by means of liquid chromatography and mass spectrometryL. Frensemeier1, G. Köllensperger2, C.R. Kowol3, B.K. Keppler3, U. Karst1
1 University of Münster, Institute of Inorganic and Analytical Chemistry, Münster, Germany; 2 University of Vienna, Institute of Analytical Chemistry, Vienna, Austria; 3 University of Vienna, Institute of Inorganic Chemistry, Vienna, Austria
60 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP13-O3-Th - Isomer separations of plasma metabolites by differential mobility coupled to tandem mass spectrometryS. Wernisch1, T. Rajendiran2,3, S. Pennathur1,3
1 University of Michigan, Internal Medicine, Ann Arbor, USA; 2 University of Michigan, Pathology, Ann Arbor, USA; 3 University of Michigan, Michigan Regional Comprehensive Metabolomics Resource Core, Ann Arbor, USA
HYP 14 High-throughput, data processing and bioinformaticsHYP14-KN-Th - Bayesian methods for data analysis in HPLC: A paradigm shiftG. Vivo-TruyolsUniversity of Amsterdam, Amsterdam, The Netherlands
HYP14-O1-Th - How to quickly find a desired separation? Integration of information and decision-making in chromatographyP. WiczlingMedical University of Gdańsk, Department of Biopharmaceutics and Pharmacodynamics, Gdańsk, Poland
HYP14-O2-Th - Liquid chromatography, mass spectrometry and chemometrics for the identification of frauds in extra-virgin olive oil authenticationO. Nuñez1,2,3, M. Said1, N. Carranco1, D. Filatova1, M. Farrés-Cebrián1, J. Saurina1,3, E. Morano1
1 University of Barcelona, Chemical Engineering and Analytical Chemistry, Barcelona, Spain; 2 Serra Hunter Program - Generalitat de Catalunya, Barcelona, Spain; 3 Research Institute of Food Nutrition and Food Safety- University of Barcelona, Santa Coloma de Gramenet, Spain
HYP14-O3-Th - Pushing the speed limit for high throughput LC-MS analysis in support of pharmaceutical development researchK. Zawatzky, C.J. WelchMerck & Co.- Inc., Process and Analytical Chemistry, Rahway, USA
Program track Applications (APP)APP 1 Forensics, doping and toxicologyAPP1-KN-Mo - Testing non-approved substances using alternative matrices and liquid chromatography / high- and low-resolution tandem mass spectrometry in doping controlsM. ThevisGerman Sport University Cologne, Köln, Germany
APP1-O1-Mo - Doping control analysis of prohibited peptide drugs after sophisticated metabolism studies by means of liquid chromatography coupled to HR-MS/MSA. Thomas, W. Schänzer, M. ThevisGerman Sport University, Institute of Biochemistry, Cologne, Germany
APP1-O2-Mo - Exploring blood steroidomics for the improvement of the athlete biological passport steroidal moduleF. Ponzetto1, J. Boccard2,3, G.M. Randazzo2,3, R. Nicoli1, T. Kuuranne1, M. Saugy4, S. Rudaz2,3
1 Swiss Laboratory for Doping Analyses, University Center of Legal Medicine Geneva and Lausanne- Centre Hospitalier Universitaire Vaudois and University of Lausanne, Epalinges, Switzerland; 2 School of Pharmaceutical Sciences- University of Geneva- University of Lausanne, Geneve, Switzerland; 3 Swiss Center of Applied Human Toxicology SCAHT- University of Basel, Geneve, Switzerland; 4 Center of Research & Expertise in anti-doping Sciences- University of Lausanne, Institute of Sports Sciences of the Lausanne University, Lausanne, Switzerland
APP1-O3-Mo - Validation of a fast ionic liquid-based dispersive liquid-liquid microextraction procedure combined with LC-MS/MS analysis for the quantification of benzodiazepines in whole bloodM. De Boeck1, S. Missotten1, W. Dehaen2, J. Tytgat1, E. Cuypers1
1 KU Leuven, Department of Pharmaceutical and Pharmacological Sciences - Toxicology and Pharmacology, Leuven, Belgium;
2 KU Leuven, Department of Chemistry - Molecular Design and Synthesis, Leuven, Belgium
61HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP 2 ProteomicsAPP2-KN-Mo - Protein-protein interaction studies of disease networksJ. Yates1, B.D. Stein2, D. Calzolari2, M. Lavallée-Adam3
1 The Scripps Research Institute, La Jolla, USA; 2 The Scripps Research Institute, Chemical Physiology and Molecular and Cellular Neurobiology, La Jolla, USA; 3 University of Ottawa, Biochemistry- Microbiology- Immunology, Ottawa, Canada
APP2-O1-Mo - Proteome- and phosphoproteome analysis of onkogenic signaling pathwaysC.G. Huber1, T. Scheidt1, H. Jorge2, W. Gruber1, M. Dell'Aica2, R. Zahedi2, F. Aberger1
1 University of Salzburg, Department of Molecular Biology, Salzburg, Austria; 2 Leibnitz Institute of Analytical Sciences ISAS, Dortmund, Germany
APP2-O2-Mo - Better access to proteoforms by cold vaporization of tissues with picosecond-infrared-laser (PIRL) ablationM. Kwiatkowski1, M. Wurlitzer2, S. Uschold3, R.J.D. Miller3, H. Schlüter2
1 University Medical Center Groningen, Department of Pulmonary Diseases and Tuberculosis, Groningen, The Netherlands;
2 University Medical Center Hamburg-Eppendorf, Institute of Clinical Chemistry and Central Laboratories, Hamburg, Germany;
3 Max Planck Institute for the Structure and Dynamics of Matter, Hamburg, Hamburg, Germany
APP2-O3-Mo - Surfactant-free coacervation of natural cell membranes for facile, selective extraction, and enrichment of integral membrane proteins in proteomicsM. Khaledi1, A. Koolivand1, N. Weisner2, X. Qiao1, M. Azizi11 University of Texas-Arlington, Chemistry and Biochemistry, Arlington- TX, USA; 2 North Carolina State University, Chemsitry, Raleigh, USA
APP 3 Sample preparation and automationAPP3-KN-Mo - Why are thin coated sampling/extraction devices with biocompatible sorbents well suited for coupling of biological systems to liquid chromatography/mass spectrometry?J. PawliszynUniversity of Waterloo, Waterloo, Canada
APP3-O1-Mo - Novel online sample preparation media for complicated samples analysis coupling with high-performance liquid chromatographyG. Li, G. Li, X. Luo, Q. Zhang, X. Yang, Y. Hu, X. XiaoSchool of Chemistry- Sun Yat-sen University, Guangzhou, China
APP3-O2-Mo - Isoform enrichment by recycling chromatographyM. Morbidelli, N. UlmerETH Zurich, Zurich, Switzerland
APP3-O3-Mo - Does parallel artificial liquid membrane extraction match the requirements for an applicable and high-throughput sample preparation method from biological matrices?A. Gjelstad1, G. Wong1, P.O. Grafinski1, K.S. Ask1, L. Vårdal1, E.L. Øiestad2, S. Pedersen-Bjergaard1
1 School of Pharmacy, Department of Pharmaceutical Chemistry - University of Oslo, Oslo, Norway; 2 Norwegian Institute of Public Health, Forensic science, Oslo, Norway
APP 4 MetabolomicsAPP4-KN-Mo - Metabolomics: From differential metabolite discovery to functional elucidationG. Xu, Y. Zhou, Z. Wang, P. Yin, H. Piao, X. LuDalian Institute of Chemical Physics- Chinese Academy of Sciences, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian, China
APP4-O1-Mo - Comprehensive and quantitative profiling of the human blood metabolome from one microliter of finger blood L. Li, H. WeiDepartment of Chemistry, University of Alberta, Edmonton, Alberta T6G2G2, Canada
62 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP4-O2-Mo - Improving metabolite coverage in global metabolomics using sequential extractionD. Sitnikov, C. Monnin, D. VuckovicConcordia University, Chemistry and Biochemistry, Montreal, Canada
APP4-O3-Mo - Derivatization strategies for targeted metabolomicsP. Malec, R. KennedyUniversity of Michigan, Chemistry, Ann Arbor, USA
APP 5 Chiral separationsAPP5-KN-Tu - Recent trends in application of polysaccharide-based chiral selectors for liquid phase separation of enantiomersB. ChankvetadzeTbilisi State University, Tbilisi, Georgia
APP5-O1-Tu - Capillary electrophoresis in the determination of the stereoisomeric purity of drugsG. Scriba, S. Niedermeier, H. Harnisch, S. KraitFriedrich Schiller University, Jena, Germany
APP5-O2-Tu - Three-dimensional HPLC analysis of amino acid enantiomers in complicated real world samplesK. Hamase1, R. Koga1, Y. Miyoshi1,2, M. Mita2, W. Lindner3
1 Kyushu University, Graduate School of Pharmaceutical Sciences, Fukuoka, Japan; 2 Shiseido Co. Ltd., Tokyo, Japan; 3 University of Vienna, Institute of Analytical Chemistry, Vienna, Austria
APP5-O3-Tu - Further studies on the HILIC character of polysaccharide-based chiral stationary phases in polar organic separation modeB. Chankvetadze1, A. Felinger2, T. Farkas3
1 Tbilisi State University, Institute of Physical and Analytical Chemistry- School of Exact and Natural Sciences, Tbilisi, Georgia;
2 University of Pécs, Department of Analytical and Environmental Chemistry, Pécs, Hungary; 3 Phenomenex Inc., Research and Development, Torrance, USA
APP 6 LipidomicsAPP6-KN-Tu - Natural variation of blood plasma lipids in healthy Asian individualsM.R. WenkNational University of Singapore, Singapore, Singapore
APP6-O1-Tu - Lipidomic analysis of plasma in patients with lacunar infarction using normal-phase / reversed-phase 2D LC-MS/MSH. Liu1, L. Yang1, P. Lv2, Y. Bai1, Y. Huang2
1 Peking University, College of Chemistry and Molecular Engineering, Beijing, China; 2 Peking University First Hospital, Department of Neurology, Beijing, China
APP6-O2-Tu - Lipidomic analysis of biological samples: comparison of liquid chromatography, supercritical fluid chromatography and direct infusion mass spectrometry methodsM. Lísa, E. Cífková, M. Khalikova, M. Ovčačíková, M. HolčapekUniversity of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic
APP6-O3-Tu - Ion mobility as additional separation dimension to tackle the complexity of the Caenorhabditis elegans lipidomeA. Laurençon1, J. Thiemann2, V. Gnau2, J. Uhl3, H. Aguilaniu1, M. Witting3
1 ENS de Lyon, Institut de Génomique Fonctionnelle de Lyon, Lyon, France; 2 Agilent Technologies, Waldbronn, Germany;
3 Helmholtz Zentrum München, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany
APP 7 Affinity separationsAPP7-KN-Tu - The use of specific interactions with fullerenes in microscale liquid phase separationsK. Otsuka, T. Kubo, E. Kanao, S. Tokuda, T. NaitoKyoto University, Graduate School of Engineering, Kyoto, Japan
63HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP7-O1-Tu - Personalized medicine based on high-performance affinity microcolumns: Drug-protein binding studies with modified proteins and clinical samplesD. Hage, C. Bi, S. Beeram, Z. Chenhua, R. Matsuda, X. ZhengUniversity of Nebraska, Chemistry Department, Lincoln- Nebraska, USA
APP7-O2-Tu - Affinity capillary electrophoresis for ligand binding assays: Playing the ACE cardH. Wätzig1, I. Oltmann-Norden1, M. Mozafari1, H. AlHazmi2, M. Nachbar1, D. Abd El-Hady3, S. El Deeb1
1 University of Braunschweig, Braunschweig, Germany; 2 Jazan University, Jazan, Saudi Arabia; 3 University of Jeddah, Jeddah, Saudi Arabia
APP7-O3-Tu - “Lab on chip” – biomimetic channel networksA. ManzKIST Europe, Saarbrücken, Germany
APP 8 Glycomics and glycoproteomics - Celebrating Miloš Novotný 75th birthdayAPP8-KN-Tu - LC and LC-MS in service of analytical glycoscienceM.V. NovotnýIndiana University, Bloomington, USA
APP8-O1-Tu - Temperature gradient capillary electrophoresisA. Guttman, M. SzigetiUniversity of Debrecen, HLBS, Debrecen, Hungary
APP8-O2-Tu - Development of a rapid and robust n-glycan analysis workflow for both LC and CE platformsA. Eckard, B. Kunnummal, P.A. BellThermoFisherScientific, Bio Production- Pharma Analytics, South San Francisco, USA
APP8-O3-Tu High sensitive CE-MS analysis of positively charged oligosaccharidesJ. Krenkova, J. Partyka, F. ForetInstitute of Analytical Chemistry of the CAS v. v. i., Bioanalytical Instrumentation, Brno, Czech Republic
APP 9 Recent advances in (bio)pharmaceuticals I.APP9-KN-We - Two dimensional liquid chromatography: From clone selection to detailed characterization of monoclonal antibodies and antibody-drug conjugatesK. Sandra, I. Vandenheede, M. Steenbeke, G. Vanhoenacker, P. SandraResearch Institute for Chromatography, Kortrijk, Belgium
APP9-O1-We - Manufacturability assessment of monoclonal antibodies using advanced LC-MSJ. Bones, A. Trappe, F. Fuessl, S. Millan-Martin, S. Mittermayr, A. FarrellNational Institute for Bioprocessing Research and Training, Characterisation and Comparability, Dublin, Ireland
APP9-O2-We - HILIC-MS: A powerful analytical tool for the profiling of glycosylation patterns of biopharmaceutical proteins at the middle-up levelV. D'Atri1, S. Fekete1, A. Beck2, J.L. Veuthey1, D. Guillarme1
1 University of Geneva, School of Pharmaceutical Sciences, Geneva, Switzerland; 2 Center of Immunology Pierre Fabre, Saint-Julien-en-Genevois, France
APP9-O3-We - De-conjugation coupled with LC-MS for investigating the stability of small molecule drugs in antibody-drug conjugatesT. Chen1, D. Su2, J. Gruenhagen1, Y. Li1, P. Yehl1, N. Chetwyn1, C. Medley1
1 Genentech Inc, Small Molecule Pharmaceutical Sciences, South San Francisco, USA; 2 Genentech Inc, Assay Development & Technology, South San Francisco, USA
APP 10 Recent advances in (bio)pharmaceuticals II.APP10-KN-We - Multiplexed mLC-nLC for comprehensive impurity profiling: A method development "free" platformK. Zhang, S. Yang, J. Lin, M. TsangGenentech, South San Francisco, USA
64 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP10-O1-We - Leveraging chromatographic speed and efficiency: Integration of analytical SFC into pharmaceutical analysisY. Huang, M. CoutantPfizer Worldwide Research & Development, Analytical R&D, Groton, USA
APP10-O2-We - Native mass spectrometry for the revelation of highly complex glycosylation in biopharmaceuticalsT. Wohlschlager1,2, K. Scheffler2,3, I.C. Forstenlehner2,4, S. Senn1,2, E. Damoc5, S. Ruzek2,4, J. Holzmann2,4, C.G. Huber1,2
1 University of Salzburg, Department of Molecular Biology- Division of Chemistry and Bioanalytics, Salzburg, Austria; 2 Christian Doppler Laboratory for Innovative Tools for Biosimilar Characterization, Salzburg, Austria; 3 Thermo Fisher Scientific GmbH, Dreieich, Germany; 4 Sandoz, Novartis Technical Operations Biologics Technical Development & Manufacturing, Kundl, Austria;
5 Thermo Fisher Scientific GmbH, Bremen, Germany
APP10-O3-We - Improved chromatographic conditions for the characterization of antibody-drug conjugatesB. Bobaly, G.M. Randazzo, S. Rudaz, J.L. Veuthey, D. Guillarme, S. FeketeUniversity of Geneva- University of Lausanne, School of Pharmaceutical Sciences, Geneva, Switzerland
APP 11 Food analysisAPP11-KN-We - Multidimensional techniques for the analysis of food productsP. Dugo1, F. Cacciola2, P. Donato2, L. Mondello1
1 University of Messina, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy; 2 University of Messina, Dipartimento di Scienze Biomediche- Odontoiatriche e delle Immagini Morfologiche e Funzionali, Messina, Italy
APP11-O1-We - Study of seed coat composition in relation to dormancy and domestication - utilization of liquid chromatography and mass spectrometryP. Bednář1, M. Cechová1, M. Válková1, L. Kučera1, I. Hradilová2, P. Smýkal2, A. Janská3, A. Soukup3
1 Regional Centre of Advanced Technologies and Materials- Department of Analytical Chemistry- Faculty of Science- Palacký University, Olomouc, Czech Republic; 2 Department of Botany- Faculty of Science- Palacký University, Olomouc, Czech Republic;
3 Department of Experimental Plant Biology- Faculty of Science- Charles University, Praha, Czech Republic
APP11-O2-We - Insights into structure-bioaccessibility relationships of polyphenols in red chicory by HPLC-MS/MSN. Marchetti, A. Cavazzini, L. Pasti, A. Maietti, C. BergantinUniversity of Ferrara, Chemistry and Pharmaceutical Sciences, Ferrara, Italy
APP11-O3-We - Discovery of bioactive peptides from Cauliflower (Brassica oleracea) waste protein using a scaled up chromatographic approachR. Zenezini Chiozzi, A.L. Capriotti, C. Cavaliere, C.M. Montone, A. LaganàUniversity of Rome la Sapienza, Chemistry, Rome, Italy ¨
APP 12 Natural productsAPP12-KN-We - Supercritical fluid chromatography (SFC) profiling of hops bittering acids and derivatives using chiral columnsT. Berger1, B. Berger2, E. Wilson3
1 SFC Solutions Inc., Separation Science, Englewood, USA; 2 Leiden University, Institute of Biology Leiden, Leiden, The Netherlands; 3 Leiden University, Natural Products Laboratory, Leiden, The Netherlands
APP12-O1-We - Characterization of saffron marker- and aroma compounds by one- and comprehensive two-dimensional HPLC-IT-TOF-MS analysisP. Hashemi, E. RosenbergVienna University of Technology, Institute of Chemical Technologies and Analytics, Vienna, Austria
APP12-O2-We - Comprehensive two-dimensional centrifugal partition chromatography- liquid chromatography (CPC x LC): Providing preparative separation for complex plant extractsK. Faure, L. Marlot, M. BatteauCNRS Université Lyon 1, Institut des Sciences Analytiques, Villeurbanne, France
65HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP12-O3-We - Chromatographic analysis of alkaloids in Aconitum pollen: towards new insights in plant protection mechanismsM. Vanderplanck1, G. Glauser2, E. Tyteca1, D. Michez3, C. Praz4
1 University of Liège - Gembloux Agro-Bio-Tech, Analytical Chemistry- AgroBioChem Department, Gembloux, Belgium;
2 University of Neuchatel, Neuchâtel Platform of Analytical Chemistry, Neuchâtel, Switzerland; 3 University of Mons, Laboratory of Zoology- Research Institute for Biosciences, Mons, Belgium; 4 University of Neuchatel, Laboratory of Evolutionary Entomology- Institute of Biology, Neuchâtel, Switzerland
APP 13 Clinical analysisAPP13-KN-Th - Digging deeper into the metabolome: Adding ion mobility spectrometry as a 3rd dimension to biomarker discovery and analysis via UPLC-IMS-MSI.D. WilsonImperial College, London, United Kingdom
APP13-O1-Th - Assessment of biogenic amines along with their precursors and metabolites supported by new sample pretreatment and separation solutionsT. BaczekMedical University of Gdansk, Department of Pharmaceutical Chemistry, Gdansk, Poland
APP13-O2-Th - One-minute separation of five biothiols using amide-modified liquid chromatography chipM. Tsunoda1, M. Isokawa1, K. Nakanishi2, T. Funatsu1, S. Shoji21 University of Tokyo, Graduate School of Pharmaceutical Sciences, Tokyo, Japan; 2 Waseda University, Tokyo, Japan
APP13-O3-Th - Untargeted metabolomics in diagnosing inherited metabolic diseasesD. Friedecký1, L. Najdekr1, A. Gardlo1, L. Kluijtmans2, R. Wevers2, T. Adam1
1 Palacký University and University Hospital Olomouc, Laboratory of Metabolomics and Laboratory for Inherited Metabolic Disorders, Olomouc, Czech Republic; 2 Radboud University Medical Centre, Department Laboratory Medicine, Nijmegen, The Netherlands
APP 14 Environmental analysisAPP14-KN-Th - Investigations on the metabolization of non-steroidal anti-inflammatory drugs in cress (Lepidium sativum) grown hydroponically in drug contaminated waterC. Klampfl, L. Emhofer, M. Himmelsbach, W. BuchbergerJohannes-Kepler-University, Analytical Chemistry, Linz, Austria
APP14-O1-Th - Characterization of fast pyrolysis oils using supercritical fluid chromatography – mass spectrometry and chemometric data analysisJ.S. Lübeck1, K. G. Poulsen1, G. Tomasi1, S. Verdier2, A. B. Hansen2, D. C. Dayton3, O. D. Mante3, J.H. Christensen1
1 University of Copenhagen, Plant and Environmental Sciences, Frederiksberg, Denmark; 2 Haldor Topsoe A/S, Kgs. Lyngby, Denmark; 3 RTI International, Energy Technology Division, Durham- North Carolina, USA
APP14-O2-Th - Microporous organogel materials for sample preparation and green sfc and u-hplc separationsJ.C. Garrigues1, S. Franceschi2, E. Perez3
1 CNRS, IMRCP Laboratory, Toulouse, France; 2 Université Paul Sabatier, Toulouse, France; 3 CNRS, Toulouse, France
APP14-O3-Th - Residue analysis of pharmaceuticals in plantsW. Buchberger, L. Emhofer, B. Reichl, C. Klampfl, M. HimmelsbachJohannes-Kepler-University Linz, Analytical Chemistry, Linz, Austria
Program track Young and Tutorials (YOU)YOU 1 2D-LCYOU1-TU-Mo - Two-dimensional chromatography: A tutorialM. SchureKroungold Analytical- Inc, Theoretical Separation Science Laboratory, Blue Bell, USA
66 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU1-SO1-Mo - Chip-based HPLC with an integrated droplet interface for surface enhanced raman detectionR. Gerhardt, A.J. Peretzki, D. BelderUniversity of Leipzig, Institute of Analytical Chemistry, Leipzig, Germany
YOU1-SO2-Mo - Membrane evaporative interface for LCxLCE. Fornells1, B. Barnett2, M. Bailey3, R.A. Shellie3, E.F. Hilder4, M.C. Breadmore5
1 University of Tasmania, ARC Training Centre for Portable Analytical Separation Technologies - ASTech, Hobart, Australia;
2 Trajan Scientific and Medical, Melbourne, Australia; 3 Trajan Scientific and Medical, ARC Training Centre for Portable Analytical Separation Technologies - ASTech, Melbourne, Australia; 4 University of South Australia Future Industries Institute, ARC Training Centre for Portable Analytical Separation Technologies - ASTech, Adelaide, Australia; 5 University of Tasmania, Australian Centre for Research on Separation Science, Hobart, Australia
YOU1-SO3-Mo - Increasing flexibility in two-dimensional liquid chromatography by pulsed elution of the first dimension (Pulsed-elution 2D-LC)N.J. Nielsen1, S.S. Jakobsen1,2, S. Verdier2, A.B. Hansen2, J.H. Christensen1
1 University of Copenhagen, Plant and Environmental Science, Frederiksberg, Denmark; 2 Haldor Topsoe A/S, Kgs. Lyngby, Denmark
YOU1-SO4-Mo - Two-dimentional LC for analysis of monoclonal antibody during bioprocess developmentJ.H. Heo, D. Richardson, S. YuMSD, Bioprocess Development, Kenilworth- NJ, USA
YOU 2 Separation mechanismsYOU2-TU-Mo - Effect of salts on retention of neutral solutes in HILICA. AlpertPolyLC Inc., Colombia, USA
YOU2-SO1-Mo - Numerical study of the thermal conductivity of columns packed with fully porous and superficially porous particlesS. Deridder, K. Broeckhoven, G. DesmetVrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium
YOU2-SO2-Mo - Dual retention mechanism on stationary phases with embedded polar groupK. Krzemińska, S. Bocian, B. BuszewskiNicolaus Copernicus University, Chair of Environmental Chemistry & Bioanalitics, Torun, Poland
YOU2-SO3-Mo - Transport of molecules of different sizes through monolithic, core-shell and porous silica columns. Effect of porous silica architectureK.L. Nguyen1,2, V. Wernert1, R. Denoyel1, A. Galarneau3, Y. Didi31 MADIREL, Aix-Marseille University, Marseille, France; 2 Hanoi University of Mining and Geology, Hanoi, Viet Nam; 3 Institut Charles Gerhardt Montpellier, Montpellier, France
YOU2-SO4-Mo - Solvation processes in liquid chromatography - the importance and measurementS. Bocian, M. Skoczylas, K. Krzemińska, B. BuszewskiNicolaus Copernicus University, Toruń, Poland
YOU 3 ProteomicsYOU3-TU-Mo - The role of separations in protein and proteomic mass spectrometric analysisB.L. KargerNortheastern University, Boston, USA
YOU3-SO1-Mo - Characterization of a poly(dimethylsiloxane) microfluidic chip containing immobilized trypsin for rapid protein digestionA. Kecskemeti, C.N. Nagy, A. GasparUniversity of Debrecen, Department of Inorganic and Analytical Chemistry, Debrecen, Hungary
67HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU3-SO2-Mo - Novel approach to determine lipidated analogs of prolactin-releasing peptide via LC-MS using monolithic columnJ. Zemenová1,2, D. Sýkora2, L. Maletínská1
1 Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences, Group of Lenka Maletínská, Prague, Czech Republic; 2 University of Chemisty and Technology Prague, Department of Analytical Chemistry, Prague, Czech Republic
YOU3-SO3-Mo- Trinity P1 mixed mode chromatography enables mass spectrometry compatible orthogonal peptide separation to reversed phaseP. Yu1, M. Wilhelm1, D. Zolg1, X. Sun2, X. Liu2, A. Huhmer3, B. Kuster1
1 Technische Universität München, Freising, Germany; 2 Thermo Fisher Scientific, Sunnyvale, USA; 3 Thermo Fisher Scientific, San Jose, USA
YOU3-SO4-Mo - Predictive chromatography of peptides for optimized fractionation in bottom-up proteomicsE. Solovyeva1, A. Lobas2, A. Kopylov3, L. Levitsky2, I. Ilyina3, S. Moshkovskii3, M. Gorshkov2
1 Moscow Institute of Physics and Technology, Department of Molecular and Chemical Physics, Dolgoprudny, Russian Federation; 2 Institute for Energy Problems of Chemical Physics, Moscow, Russian Federation; 3 Institute of Biomedical Chemistry, Moscow, Russian Federation
YOU 4 Sample preparationYOU4-TU-Mo - Similarity, selectivity, and specificity (3s) - three dimensional factor determining HPLC resolutionB. Buszewski, M. Skoczyla, S. BocianNicolaus Copernicus University, Torun, Poland
YOU4-SO1-Mo - Determination of selected fat soluble vitamins from bovine milk using dispersive liquid-liquid microextraction coupled with HPLC-UV equipped with a core-shell columnA. Quigley, S. Walsh, D. Connolly, W. CumminsWaterford Institute of Technology, Department of Science, Waterford, Ireland
YOU4-SO2-Mo - Development of an HPLC bioreactor based on immobilized enterokinase for the cleavage of fusion proteinsS. Tengattini1, F. Rinaldi1, C. Temporini1, E. Calleri1, L. Piubelli2, T. Bavaro1, G. Massolini11 University of Pavia, Department of Drug Sciences, Pavia, Italy; 2 University of Insubria, Department of Biotechnology and Life Sciences, Varese, Italy
YOU4-SO3-Mo - Automated robotic sample preparation for metabolomics with hyphenation to LC-SWATH/MS acquisition for plasma and liver samplesM. Raetz1, R. Picenoni2, G. Boehm2, G. Hopfgartner1
1 University of Geneva, CHIAM, Geneve 4, Switzerland; 2 CTC Analytics, Zwingen, Switzerland
YOU4-SO4-Mo - Easy and cheap apparatus for the off-line automatization of miniaturized sample preparation techniquesD.A. Vargas Medina, L. Schwerz, D. Menini, A.J. Santos NetoUniversidade de São Paulo, Instituto de Química de São Carlos, São Carlos, Brazil
YOU 5 Metabolomics and lipidomicsYOU5-TU-Tu - High-coverage quantitative metabolomics using chemical isotope labeling LC-MSL. LiUniversity of Alberta, Edmonton, Canada
YOU5-SO1-Tu - Use of a novel linear retention index system as identification tool in liquid chromatography: Applications in lipidomicsF. Rigano1, P. Dugo1,2, L. Mondello1,2
1 Chromaleont S.r.L., Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy; 2 University of Messina, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy
YOU5-SO2-Tu - Simultaneous non-polar and polar lipid analysis by complementary online two-dimensional liquid chromatography and high resolution mass spectrometryE. Rampler, B. Mitic, M. Schwaiger, G. KoellenspergerUniversity of Vienna, Analytical Chemistry, Vienna, Austria
68 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU5-SO3-Tu - Oxysterols in cancerH. Roberg-Larsen1, F. Sved Skottvol1, K. Bjørseth1, S. Solheim1, E. Lundanes1, J. Thorne2, S. Ray Wilson1
1 University of Oslo, Chemistry, Oslo, Norway; 2 University of Leeds, School of Food Science, Leeds, United Kingdom
YOU5-SO4-Tu - Increasing peak capacity and selectivity of LC-MS by incorporation of low-field drift-tube ion mobility separationT. Causon, S. HannUniversity of Natural Resources and Life Sciences BOKU Vienna, Department of Chemistry, Vienna, Austria
YOU 6 Chiral and achiral stationary phasesYOU6-TU-Tu - Principles of enantioseparations in LC: State of the art, quo vadisW. Lindner1, M. Kohout2, M. Laemmerhofer3
1 University of Vienna, Departmant of Analytical Chemistry- Faculty of Chemistry, Vienna, Austria; 2 UCT Prague, Organic Chemistry, Prague, Czech Republic; 3 University of Tuebingen, Pharmaceutical Analysis and Bioanalysis, Tuebingen, Germany
YOU6-SO1-Tu - Stationary phase optimized selectivity chiral liquid chromatography (SOS-CLC) as a novel perspective for the separation of stereoisomersR. Hegade, F. LynenGhent University- Belgium, Separation Science Group- Department of Organic & Macromolecular chemistry- Faculty of Sciences- Ghent University, Ghent, Belgium
YOU6-SO2-Tu - Flavanones enantioseparation by LC-ESI-MS/MS and its applicationI. Baranowska, J. Hejniak, S. BajkaczSilesian University of Technology- Faculty of Chemistry, Department of Inorganic- Analytical Chemistry and Electrochemistry, Gliwice, Poland
YOU6-SO3-Tu - Multi-parametric characterization of amino acids- and peptide-silica stationary phases - a column selection for separation targetsM. Skoczylas, S. Bocian, B. BuszewskiNicolaus Copernicus University, Toruń, Poland
YOU6-SO4-Tu - Nitrogen-incorporated tetrahedral amorphous carbon thin-films - a new electrode for the HPLC-EC of biological and environmental analytesR. Jarosova1,2, A. Castiaux1, J. Qiu3, G. Swain1
1 Michigan State University, Chemistry, East Lansing, USA; 2 Charles University in Prague, University Research Centre UNCE "Supramolecular Chemistry"- Department of Analytical Chemistry- UNESCO Laboratory of Environmental Electrochemistry-, Prague, Czech Republic; 3 Illinois Mathematics and Science Academy, Illinois, USA
YOU 7 Ultrahigh-resolution mass spectrometryYOU7-TU-Tu - Theory and practice of orbitrap mass spectrometry A. MakarovThermo Fisher Scientific, Bremen, Germany
YOU7-SO1-Tu - Pharmacokinetics and brain uptake study of novel AMPA receptor antagonist perampanel in Sprague Dawely rats using a validated UHPLC-QTOF-MS methodD. Paul, L. Allakonda, A. Sahu, S. Surendran, P. Johnsi Rani, R.P. Sayali, S. Nanjappan1 National Institute of Pharmaceutical Education and Research NIPER-Hyderabad, Pharmaceutical Analysis, Hyderabad, India
YOU7-SO2-Tu - Analysis of chestnut tannins by reversed phase- and hydrophilic interaction chromatography coupled to ion mobility and high resolution mass spectrometryP. Venter, A. de Villiers, H. PaschUniversity of Stellenbosch, Department of chemistry and polymer science, Stellenbosch, South Africa
YOU7-SO3-Tu - Solid phase microextraction and liquid chromatography coupled to high resolution mass spectrometry: A powerful platform for in vivo brain metabolomics studiesN. Reyes Garces1, E. BoyacI1, G.A. Gomez Rios1, B. Bojko1, D. Vuckovic2, C. Hamani3, J. Pawliszyn1
1 University of Waterloo, Chemistry, Waterloo, Canada; 2 Concordia University, Montréal, Canada; 3 University of Toronto, Neurosurgery, Toronto, Canada
69HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU7-SO4-Tu - Measuring steroid profiles in whale blubber by liquid chromatography tandem mass spectrometryA. Boggs1, T. Schock1, L. Schwacke2, T. Galligan3, J. Morey4, W. McFee4, J. Kucklick1
1 National Institute of Standards and Technology, Charleston, USA; 2 National Marine Mammal Foundation, Chalreston, USA;
3 Medical University of South Carolina, Charleston, USA; 4 National Oceanic and Atmospheric Administration, Charleston, USA
YOU 8 Electromigration techniquesYOU8-TU-Tu - Capillary electrophoresisE.S. YeungIowa State University, Ames, USA
YOU8-SO1-Tu - Optimisation of an electrophoretic approach for the screening and the development of new antithrombotic drugsE. Farcaş1, C. Bouckaert2, A.C. Servais1, J. Crommen1, L. Pochet2, M. Fillet1
1 University of Liège, Department of Pharmacy- Laboratory for the Analysis of Medicines- CIRM, Liège, Belgium; 2 University of Namur, Namur Medicine & Drug Innovation Center NaMEDIC- Narilis, Namur, Belgium
YOU8-SO2-Tu - Two-dimensional capillary zone electrophoresis coupled to mass spectrometry for the characterization of monoclonal antibody charge variants on the intact levelK. Jooß1,2, J. Hühner1,3, C. Neusüß1
1 Aalen University of Applied Sciences, Faculty of Chemistry, Aalen, Germany; 2 Helmholtz Zentrum München, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany; 3 University of Tübingen, Institute of Pharmaceutical Science, Tübingen, Germany
YOU8-SO3-Tu - Single-isomer cyclodextrin derivatives in chiral capillary electrophoresis: The past, the present and the futureE. Varga, T. Sohajda, L. SzenteCyclolab Cyclodextrin R&D Ltd., Budapest, Hungary
YOU8-SO4-Tu - Capillary electrophoresis-mass spectrometry as a novel technique in analysis of cholesterol and its metabolitesM. GregusDepartment of Chemistry, Masaryk University, Brno, Czech Republic
YOU 9 Monolithic columnsYOU9-TU-We - Monolithic columns: Why, how, and for what?F. ŠvecBeijing University of Chemical Technology, Beijing, China
YOU9-SO1-We - Macroscopic three dimensional carbon nanohorns monolith for (micro)solid-phase extraction of volatile organic compoundsB. Fresco, S. CárdenasUniversity of Córdoba, Analytical Chemistry, Córdoba, Spain
YOU9-SO2-We - Preparation and analytical application of novel anion-exchangers for ion chromatography with improved selectivity toward organic acidsA. Zatirakha, O. Shchukina, A. Uzhel, A. Gorbovskaya, R. Ogorodnikov, A. Smolenkov, O. ShpigunLomonosov Moscow State University, Chemistry department, Moscow, Russian Federation
YOU9-SO3-We - Variation of parameters influencing the immobilization of ligands onto epoxy-modified silica monolithsB. Peters1, T. Kupfer1, E. Machtejevas2, G. Jung1, P. Knoell11 Merck, Analytical R&D, Darmstadt, Germany; 2 Merck, Advanced Analytical, Darmstadt, Germany
YOU9-SO4-We - Development of monolithic capillary column with an integrated electrochemical detector for the determination of dopamine in urineM. Komendová1, R. Metelka1, J. Urban2
1 University of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic; 2 Masaryk University, Department of Chemistry, Brno, Czech Republic
70 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU 10 SFC and SFC/MSYOU10-TU-We - Supercritical fluid chromatography (SFC)I. FrancoisWaters, Guyancourt, France
YOU10-SO1-We - Online supercritical fluid extraction-supercritical fluid chromatography-mass spectrometry for carotenoids determination in red habanero peppersM. Zoccali1, D. Giuffrida2, P. Dugo1,3,4, L. Mondello1,3,4
1 Chromaleont srl, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy; 2 University of Messina, Dipartimento di Scienze Biomediche- Odontoiatriche e delle Immagini Morfologiche e Funzionali, Messina, Italy;
3 University Campus Bio-Medico of Rome, Unit of Food Science and Nutrition- Department of Medicine, Rome, Italy; 4 University of Messina, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy
YOU10-SO2-We - Development of novel poly(vinylpyridine)-based SFC columns and their applicationsK. Nagai1, S. Shinkura1, T. Shibata1, Y. Yoshimoto2, A. Ohnishi21 DAICEL Corporation, CPI company, Himeji, Japan; 2 DAICEL Corporation, CPI company, Myoko, Japan
YOU10-SO3-We - Influence of sample injection solvent on peak shape for the analysis of pharmaceutical compounds in SFCV. Desfontaine1, A. Tarafder2, J. Fairchild2, J. Hill2, J.L. Veuthey1, D. Guillarme1
1 University of Geneva, Analytical Sciences, Genève, Switzerland; 2 Waters Corporation, Research, Milford, USA
YOU10-SO4-We - UHPSFC/ESI-MS lipidomic analysis of tissues and plasma from kidney cancer patientsM. Khalikova1, M. Lísa1, E. Cífková1, D. Vrána2, B. Melichar2, V. Študent3, M. Holčapek1
1 University of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic; 2 Palacký University, Medical School and Teaching Hospital- Department of Oncology, Olomouc, Czech Republic; 3 Palacký University, Faculty of Medicine and Dentistry- Department of Urology, Olomouc, Czech Republic
YOU 11 Pharmaceutical analysisYOU11-TU-We - Biosimilars evolution and demands on analytical scientistsL.A. BeaverLAB Enterprises, USA
YOU11-SO1-We - Metabolic study of methylstenbolone in horsesL.S. Choi1, J.K.Y. Wong1, W.H. Kwok1, P. Curl2, T.S.M. Wan1
1 The Hong Kong Jockey Club, Racing Laboratory, Hong Kong, Hong Kong; 2 The Hong Kong Jockey Club, Department of Veterinary Regulation and Biosecurity Policy, Hong Kong, Hong Kong
YOU11-SO2-We - Analytical quality by design - a methodical approach for the quantitative estimation of teriflunomide from human plasmaA. Ayre, M. Bhavsar, P. ChaudhariDr. L. H. Hiranandani College of Pharmacy, Quality Assurance, Ulhasnagar- Thane, India
YOU11-SO3-We - Exploring mixed-mode HPLC as an alternative to reversed phase HPLC for impurity profiling of drug candidatesE. Lemasson1, Y. Richer1, S. Bertin2, P. Hennig2, E. Lesellier1, C. West1
1 ICOA, Analytical Chemistry, Orléans, France; 2 Institut de Recherches Servier, Suresnes, France
YOU11-SO4-We - A normal phase chiral HPLC method for the separation of eight isomers of core + omeN. Joshi1, D. Balaji1, A. Athimoolam2, J. Paulose1, J. Tan2, L. Blue2, J. Tedrow3, F. Bob3
1 Syngene Amgen Research Center- Syngene International Limited, Bangalore, India; 2 Amgen, Attribute Science, Thousands Oak- CA, USA; 3 Amgen, Drug Substance Technologies, Thousands Oak- CA, USA
YOU 12 Scientific writing & publishingYOU12-TU1-We - Scientific writing & publishingP. HaddadAustralian Centre for Research on Separation, Hobart, Australia
71HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU12-TU2-We - Scientific writing & publishingE. HilderUniversity of South Australia, Australia
YOU12-TU3-We - Scientific writing & publishingF. ŠvecBeijing University of Chemical Technology, Beijing, China
YOU 13 Ultrahigh-performance liquid chromatographyYOU13-TU-Th - Understanding instrumental parameters that affect method transfer in UHPLC separations (some are easily overlooked)F. SteinerThermo Fisher Scientific, Germering, Germany
YOU13-SO1-Th - Exploration by UHPLC-HRMS of the enzymatic phosphorylation of pyrimidine nucleosidesJ. Ferey, D. Da Silva, C. Colas, P. Lafite, V. Roy, L. Agrofoglio, R. Daniellou, B. MaunitICOA, Orléans, France
YOU13-SO2-Th - Retention prediction in reversed phase HPLC using quantitative structure-retention relationships applied to the hydrophobic subtraction modelY. Wen1, P.R. Haddad1, M. Talebi1, R.I.J. Amos1, R. Szucs2, J.W. Dolan3, C.A. Pohl41 Australian Centre for Research on Separation Science, School of Physical Sciences-Chemistry, Hobart, Australia; 2 Pfizer Global Research and Development, Sandwich, United Kingdom; 3 LC Resources, McMinnville OR, USA; 4 Thermo Fisher Scientific, Sunnyvale CA, USA
YOU13-SO3-Th - Artificial neural network in the prediction of gradient retention times for rebaudioside A in liquid chromatographyN. Mert Ozupek1, L. Cavas2
1 Dokuz Eylül University- Graduate School of Natural and Applied Sciences, Department of Biotechnology, IZMIR, Turkey;
2 Dokuz Eylül University, Department of Chemistry, IZMIR, Turkey
YOU13-SO4-Th - Development and validation of an analytical residues method of the Aminopropyldodecylpropanediamine biocide disinfectant in dairy products by LC-MS/MSK. Slimani, Y. Pirotais, J.P. Abjean, P. Maris, D. Hurtaud-pesselAnses, Fougères, France
YOU 14 Clinical analysisYOU14-TU-Th - Sample preparation for chromatographic analysisE. HilderFuture Industries Institute, University of South Australia, Adelaide, Australia
YOU14-SO1-Th - Systems for detection of monoamines in tissues beyond brainJ. Nagler1, K.W. Schramm1, P. Pfluger2, S. Sonja2
1 Helmholtz Center Munich, MEX, Oberschleißheim, Germany; 2 Helmholtz Center Munich, IDO, Garching, Germany
YOU14-SO2-Th - Discovery and quantification of metabolic markers attributed to the activity of intestinal microbiotaT. Pavlová1, V. Vidová2, J. Bienertová-Vašků1, J. Klánová2, Z. Spáčil21 Masaryk University, Department of Pathological Physiology, Brno, Czech Republic; 2 Masaryk University, Research Centre for Toxic Compounds in the Environment RECETOX, Brno, Czech Republic
YOU14-SO3-Th - Bioactive compounds of steam-blanched and differently dried onionsL. Priecina1, D. Karklina1, I. Cinkmanis2
1 Latvia University of Agriculture, Department of Food Technology, Jelgava, Latvia; 2 Latvia University of Agriculture, Department of Chemistry, Jelgava, Latvia
YOU14-SO4-Th - Determination of phenolic acids using activated carbon-polymer extraction columnW.L. Liu, Y.C. Kuo, H.Y. HuangChung Yuan Christian University, Chemistry, Taoyuan City, Taiwan- Province of China
72 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
Program track Fundamentals (FUN)FUN 1 Characterization of HPLC stationary phases - in memory of Jack KirklandFUN1-P01-Mo - Modeling UHPLC separationsI. MolnárChromatography, Board of Management, Berlin, Germany
FUN1-P02-Mo - Sub-2-µm superficially porous particles: Is smaller better?A. Mack1, W. Long1, S. Luke2, J. Link1
1 Agilent Technologies, Wilmington, USA; 2 Agilent Technologies LDA UK Limited, Church Stretton, USA
FUN1-P03-Mo - Chromatographic behavior of biomolecules when using controlled surface charge (U)HPLC sorbentsA.C. Sanchez, I. Rustamov, M. Chitty, T. FarkasPhenomenex, Research and Development, Torrance, USA
FUN1-P04-Mo - Investigating new particle assemblies, packing and detection platforms for improved chromatographic efficiencies and speedN.M. Cantwell, V.K. Langsi, J.D. GlennonInnovative Chromatography Group, Irish Separation Science Cluster (ISSC), Department of Chemistry and the Analytical, Biological and Chemistry Research Facility (ABCRF), University College Cork, Ireland
FUN1-P05-Mo - Stationary phase selection for achiral separation of diastereomeric mixturesH. Kazoka1, A. Kreicberga1, G. Veinberg2, M. Vorona2
1 Latvian Institute of Organic Synthesys, Laboratory of Chromatography, Riga, Latvia; 2 Latvian Institute of Organic Synthesys, Laboratory of Organometallic Chemistry, Riga, Latvia
FUN1-P06-Mo - Affecting selectivity and HILIC retention on a fluorophenyl stationary phaseT. Kahler, S. Lupo, S.H. Liang, F. CarrollRestek Corporation, LC Solutions, Bellefonte, USA
FUN1-P07-Mo - Determination of the influence of temperature on the efficiency of miniaturized HPLC-columnsD. Loeker1, T. Hetzel1, T. Teutenberg1, T.C. Schmidt2
1 Institut für Energie und Umwelttechnik e.V., Forschungsanalytik, Duisburg, Germany; 2 University of Duisburg-Essen, Instrumental Analytical Chemistry, Essen, Germany
FUN1-P08-Mo - Analysis of the mass-transfer properties in chromatographic columns using the total pore blocking methodN. Lambert, A. FelingerUniversity of Pécs, Department of Environmental and Analytical Chemistry, Pécs, Hungary
FUN1-P09-Mo - Inverse gas chromatography based surface characterization of air plasma treated polydimethylsiloxane samplesB. Mészáros1, G. Járvás1,2, M. Szigeti1,2, L. Hajba2, A. Dallos3, A. Guttman1,2
1 University of Debrecen, Horvath Csaba Memorial Institute of Bioanalytical Research, Debrecen, Hungary; 2 University of Pannonia, MTA-PE Translational Glycomics Research Group, Veszprém, Hungary; 3 University of Pannonia, Department of Physical Chemistry, Veszprém, Hungary
List of Poster Presentations
Legend: FUN1-O1-Mo (Scientific session - Presentation number - Presentation day - Su – Sunday, Mo – Monday, Tu – Tuesday, We – Wednesday, Th – Thursday) PL – Plenary Lecture, O – Oral or Invited Oral Presentation, KN – Keynote Lecture, TU – Tutorial Lecture, SO – Short Oral Presentation, P – Poster, SC – Short Course
73HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN1-P10-Mo - Pyridinium-based amphiphilic side chains-branched polymer organic phases for high selective HPLCM. Shahruzzaman1, M. Takafuji2, H. Ihara2,3
1 University of Dhaka, Applied Chemistry and Chemical Engineering, Dhaka, Bangladesh; 2 Kumamoto University, Applied Chemistry and Biochemistry, Kumamoto, Japan; 3 Kumamoto Institute of Photo-Electro Organics PHOENICS, Kumamoto, Japan
FUN1-P11-Mo - Evaluation of optimized C30 phase for separation of structurally related isomersE. Shearer1, N. Nagae2, T. Tsukamoto2
1 BioNik Inc., Sales, Fuji, Japan; 2 ChromaNik Technologies Inc., r&d, Osaka, Japan
FUN1-P12-Mo - A practical, selectivity based hydrophilic interaction liquid chromatography (HILIC) method development protocolA. McKeownAdvanced Chromatography Technologies Ltd, Research and Development, Aberdeen, United Kingdom
FUN1-P13-Mo - Development of a new, highly inert ODS column with high separation performance and strong retentivityJ. Hashimoto1, K. Okusa2, Y. Yui2, M. Ohira2, Y. Otsuka1, A. Sato2, N. Gribov3, G. Alkema3
1 Fukushima R&D, R&D, Fukushima, Japan; 2 Saitama R&D, saitama R&D, Iruma, Japan; 3 GLsciences, AS Eindhoven, The Netherlands
FUN1-P14-Mo - Mushroom- or brush-type polymers on silica? Development and characterization of HILIC stationary phases modified with polyacrylamideT. Ikegami, S. TamuraKyoto Institute of technology, Faculty of Molecular Chemistry and Engineering, Kyoto, Japan
FUN1-P15-Mo - Comprehensive characterization of columns for suppressed anion chromatographyN.P. Dinh1, B. Shkodra2, T. Jonsson1
1 DIDUCO AB, Research and development, Umea, Sweden; 2 Umeå Univerisity, Chemistry, Umeå, Sweden
FUN1-P16-Mo - LC column comparison: Fully porous and core-shellC. Schultz, R. Ludwig, P. Jochems, G. Schad, T. SchüßelerShimadzu Europa GmbH, Duisburg, Germany
FUN1-P17-Mo - Solid-core particles for chromatographic separations under high pH conditionsN. Lawrence, B. Muriithi, K. Wyndham, J. Sargent, K. Glose, J. Fairchild, C. Boissel, M. DeLoffi, S. ShinerWaters Corporation, Consumables Group, Milford, USA
FUN1-P18-Mo - Tanaka-parameter based approach for chromatographic column selection: How to locate “k” columns with the most dissimilar selectivity from a selection of “n” columns in a databaseK. Kassam1, D. Tsarev1, M. Euerby2
1 Advanced Chemistry Development ACD/Labs, Toronto- Ontario, Canada; 2 University of Strathclyde, Strathclyde Institute of Pharmacy and Biomedical Sciences, Glasgow, United Kingdom
FUN1-P19-Mo - Effects of stationary phase and mobile phase modifiers on reversed-phase polypeptide selectivityE. Jones1, C. Muraco2, X. Lu2, H. Brandes2, D. Bell21 Merck, HPLC Research & Development, Bellefonte, USA; 2 Merck, Workflow Development, Bellefonte, USA
FUN1-P20-Mo - Development of a packing procedure for miniaturized HPLC columnsD. Loeker1, T. Hetzel1, T. Teutenberg1, T.C. Schmidt2
1 Institut für Energie und Umwelttechnik e.V., Forschungsanalytik, Duisburg, Germany; 2 Universität Duisburg-Essen, Instrumental Analytical Chemistry, Essen, Germany
FUN1-P21-Mo - Separation of 1,4-dihydropyridine derivative and its oxidized form under reversed-phase modeT. Upmanis, A. Kreicberga, H. KazokaLatvian Institute of Organic Synthesis, Laboratory of Chromatography, Riga, Latvia
74 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN 2 Multi-dimensional separationsFUN2-P01-Mo - Active matrix modulation for enhanced separation compatibility in two-dimensional liquid chromatographyS. Buckenmaier1, K. Shoykhet1, P. Petersson2, D. Stoll31 Agilent Technologies, Research and Development, Waldbronn, Germany; 2 Novo Nordisk A/S, Global Research, Måløv, Denmark; 3 Gustavus Adolphus College, Department of Chemistry, Saint Peter, USA
FUN2-P02-Mo - Comprehensive two-dimensional liquid chromatography for detailed characterization of nonionic surfactantsG. Vanhoenacker, M. Steenbeke, K. Sandra, P. SandraResearch Institute for Chromatography, LC, Kortrijk, Belgium
FUN2-P03-Mo - Sensitivity enhancement in two-dimensional liquid chromatography for target analysis in oligomers and pesticidesM. Pursch1, A. Wegener1, S. Buckenmaier2
1 Dow Deutschland Anlagen GmbH, Analytical Sciences, Stade, Germany; 2 Agilent Technologies, Waldbronn, Germany
FUN2-P04-Mo - A novel method and system for analytical recycle HPLCM. Minarik1,2, M. Franc1, I. Prochazkova1, M. Minarik1
1 Watrex Praha s.r.o., HPLC laboratory, Prague, Czech Republic; 2 Faculty of Science Charles University, Institute of Analytical Chemistry, Prague, Czech Republic
FUN2-P05-Mo - 2D-LC with multiple heart-cutting - Three cases where 2D-LC was the technique needed to solve impurity related problems in drug productsN.W. Jacobsen, L.D. Nielsen, J. JacobsenLEO Pharma, Analytical Support, Ballerup, Denmark
FUN2-P06-Mo - Improving peak refocusing in comprehensive two-dimensional liquid chromatography via the combination of aqueous temperature responsive with reversed phase LCM. Baert1, G. Desmet2, D.V. André3, F. Lynen1
1 Ghent University, Organic and Macromolecular Chemistry, Ghent, Belgium; 2 Vrije Universiteit Brussel, Chemical Engineering, Brussel, Belgium; 3 Stellenbosch University, Chemistry and Polymer Science, Stellenbosch, South Africa
FUN2-P07-Mo - Core-shell and fully porous quinine-derived chiral stationary phases for UHPLC, comprehensive LC x LC and LC-MS/MSU. Woiwode1, S. Neubauer1, M. Kaupert1, W. Lindner2, M. Lämmerhofer1
1 University of Tuebingen, Institute of Pharmaceutical Sciences-Pharmaceutical Bio-Analysis, Tuebingen, Germany; 2 University of Vienna, Department of Analytical Chemistry, Austria, Austria
FUN2-P08-Mo - Comparison of orthogonality of commercially available hydrophilic interaction liquid chromatography stationary phases and ion-pair reversed-phase liquid chromatographyS. Bäurer, S. Neubauer, M. LämmerhoferUniversity of Tübingen, Institute of Pharmaceutical Sciences- Pharmaceutical Bio-Analysis, Tübingen, Germany
FUN2-P09-Mo - 3D-printed microfluidic devices for spatial two-dimensional separations: Design through computational fluid dynamicsT. Adamopoulou1, S. Nawada1, S. Deridder2, B. Wouters1, P.J. Aarnoutse1, G. Desmet2, P.J. Schoenmakers1
1 University of Amsterdam, Faculty of Science, Amsterdam, The Netherlands; 2 Vrije Universiteit Brussel, Department of Chemical Engineering, Elsene, Belgium
FUN2-P10-Mo - Automated dual comprehensive HILIC×RP+RP×RP liquid chromatography for separation phenolic compoundsT. Hájek, P. Jandera, M. StaňkováUniversity of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic
FUN2-P11-Mo - Development of a two-dimensional liquid chromatography system for the separation of phosphorylated peptides in human tissueL. Roca1, A. Gargano2, G. Somsen3, P. Schoenmakers1, M. Camenzuli11 University of Amsterdam, Analytical Chemistry- HIMS, Amsterdam, The Netherlands; 2 Centre for Analytical Sciences Amsterdam, Analytical Chemistry, Amsterdam, The Netherlands; 3 Vrije Universiteit Amsterdam, Analytical Chemistry, Amsterdam, The Netherlands
75HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN2-P12-Mo - Detection of cocaine and its major metabolites in rodent bones by 2D-LC technologyC. Mallet1, M. Mella2, B. Nolan2, S. Botch-jones2, T. Moore2
1 Waters Corporation, Separation Technologies, Milford, USA; 2 Boston University School of Medicine, Boston, USA
FUN2-P13-Mo - Effective determination of pharmaceutical impurities by two-dimensional liquid chromatography (2DLC)Z. Li, P. Hong, P. McConvilleWaters, Separation technologies, Milford, USA
FUN2-P15-Mo - Fast development of LC×LC methods for the characterization of polyether polyolsG. Groeneveld1, M. Dunkle2, E. Mes2, P. Schoenmakers1
1 University of Amsterdam, Analytical Sciences, Amsterdam, The Netherlands; 2 Dow Benelux, Analytical Sciences, Terneuzen, The Netherlands
FUN2-P16-Mo - Numerical simulation of liquid chromatography – Development of a toolkit to enable deeper understanding of nonstandard conditions and advance the state of the artE. Larson1, C. Damman1, T. Brau1, H. Lhotka1, R. Sajulga1, L. Jeong2, S. Rutan2, P. Carr3, D. Stoll11 Gustavus Adolphus, Chemistry, St. Peter, USA; 2 Virginia Commonwealth University, Chemistry, Richmond, USA; 3 University of Minnesota, Chemistry, Minneapolis, USA
FUN2-P17-Mo - Preparative 2D-LC of pharmaceutical compounds with multiple chiral centersA. Dow, G. Pirrone, R. Marques, M. BibaMSD, Process Research and Development, Rahway, USA
FUN2-P18-Mo - Improving online comprehensive hydrophilic interaction chromatography × reversed phase-ultra high pressure liquid chromatography coupling by sequential-focusing modulationE.M. Sommella1, O.H. Ismail2, F. Pagano1, G. Pepe1, G. Mazzoccanti2, C. Ostacolo3, M. Russo1, E. Novellino3, F. Gasparrini2, P. Campiglia4
1 University of Reggio Calabria, Laboratory of Food Chemistry- Dipartimento di Agraria, Reggio Calabria, Italy; 2 University of Rome La Sapienza, Dipartimento di Chimica e Tecnologie del Farmaco, Rome, Italy; 3 University of Naples, Pharmacy, Naples, Italy; 4 University of Salerno, Department Difarma, Fisciano, Italy
FUN2-P19-Mo - Making analytically incompatible approaches compatibleF. van Beek1,2, B. Pirok1,2, B. Wouters1,2, R. Peters1,3, W. Genuit4, T. O'Sullivan5, M. Blom6, P. Schoenmakers1
1 University of Amsterdam, HIMS - Analytical Chemistry, Amsterdam, The Netherlands; 2 TI-COAST, Amsterdam, The Netherlands; 3 DSM Coating Resins, Waalwijk, The Netherlands; 4 Shell Global Solutions International B.V., Amsterdam, The Netherlands; 5 Heineken, Zoeterwoude, The Netherlands; 6 Micronit Microfluidics, Enschede, The Netherlands
FUN2-P20-Mo - Accumulation of D-amino acid residues in various proteins during storageC. Ishii1, T. Miyamoto2, S. Ishigo3, M. Mita3, H. Homma2, T. Ueda1, K. Hamase1
1 Kyushu University, Graduate School of Pharmaceutical Sciences, Fukuoka, Japan; 2 Kitasato University, Graduate School of Pharmaceutical Life Sciences, Tokyo, Japan; 3 Shiseido Co. Ltd., Frontier Science Business Department, Tokyo, Japan
FUN2-P21-Mo - Development of high resolution Pirkle-type chiral stationary phases and application to D-amino acid analysis in biological matricesK. Ueki1, T. Akita1, Y. Kadota2, Y. Nishio2, Y. Miyoshi3, M. Mita3, A. Ojida1, K. Hamase1
1 Kyushu University, Graduate School of Pharmaceutical Sciences, Fukuoka, Japan; 2 Shiseido Irika Technology Inc., Production Department, Kyoto, Japan; 3 Shiseido Co. Ltd, Fronteer Science Business Department, Tokyo, Japan
FUN2-P22-Mo - Development of two-dimensional liquid chromatography methods for characterization of humic substances isolated from various sourcesR. Gora, E. Beno, M. HuttaFaculty of Natural Sciences- Comenius University in Bratislava, Department of Analytical Chemistry, Bratislava, Slovakia
FUN2-P23-Mo - Microbore size-exclusion chromatography of lignin samples isolated by Klason methodsE. Beňo, R. Góra, M. HuttaComenius University in Bratislava, Department of Analytical chemistry, Bratislava, Slovakia
76 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN2-P24-Mo - Selecting orthogonal stationary phases and optimizing gradients in comprehensive 2D reversed phase LC by use of the hydrophobic subtraction- and the linear solvent strength modelN.J. Nielsen, R. Græsbøll, J.H. ChristensenUniversity of Copenhagen, Plant and Environmental Sciences, Frederiksberg, Denmark
FUN2-P25-Mo - Assessment of a new MVP stationary phase for the 2D-RPLC separation of anthraquinone derivatives using descriptors stemmed from Delaunay triangulationW. Nowik1, M. Mignot2, M. Schmitt2, A. Tchapla3, P. Cardinael2, V. Peulon-Agasse2
1 Laboratoire de Recherche des Monuments Historiques, Laboratoire de Recherche des Monuments Historiques, Champs-sur-Marne, France; 2 Normandie Université / Université de Rouen, Laboratoire SMS EA 3233, Mont Saint Aignan, France;
3 Univ-Paris Saclay IUT Orsay/Univ Paris-Sud, LETIAM/LipSys² EA 7357, Orsay, France
FUN2-P26-Mo - Optimization of maniac-assisted nanoparticle analysisN. Abdulhussain1,2, B. Pirok1,2, P. Ron1,3, P. Schoenmakers1
1 University of Amsterdam, Van 't Hoff Institute for Molecular Sciences- Analytical-Chemistry Group, Amsterdam, The Netherlands; 2 TI-COAST, Analytical Chemistry, Amsterdam, The Netherlands; 3 DSM, Coating Resins, Waalwijk, The Netherlands
FUN2-P27-Mo - Ultra-high resolution HPLC by zero dead volume recycling using park and recycle (P+R) approachM. Minarik1, M. Franc1, M. Minarik1,2
1 Watrex Praha s.r.o., HPLC laboratory, Prague, Czech Republic; 2 Faculty of Science Charles University, Department of Analytical Chemistry, Prague, Czech Republic
FUN2-P28-Mo - Design and development of a microfluidic modulator chip for comprehensive two-dimensional liquid chromatographyJ. De Vos, A. Cortijo-Martín, G. Desmet, S. EeltinkVrije Universiteit Brussel, Chemical Engineering, Brussels, Belgium
FUN2-P29-Mo - Matching 1st and 2nd dimension in the 2D-LC. Active solvent modulation vs. continuous dilutionK. Shoykhet, K. Witt, S. BuckenmaierAgilent Technologies, Research & Development, Waldbronn, Germany
FUN2-P30-Mo - Investigations of modifiers on the gas phase separation selectivity in differential mobility spectrometry-mass spectrometryD. Ruskic1, G. Hopfgartner2
1 University of Geneva, Geneve, Switzerland; 2 University of Geneva, Department of Inorganic and Mineral Chemistry, Geneve, Switzerland
FUN 3 Mechanisms of mass transport phenomenaFUN3-P01-Mo - Experimental and theoretical study of kinetic performance of modern fully porous and superficially porous C18 columnsS. Felletti1, M. Catani1, A. Cavazzini1, O.H. Ismail2, F. Gasparrini2, M. Morbidelli3, D.S. Bell41 University of Ferrara, Department of Chemical and Pharmaceutical Sciences, Ferrara, Italy; 2"Sapienza" University of Rome, Drug Chemistry and Technology, Rome, Italy; 3 Institute of Chemical and Bioengineering, Chemistry and Applied Bioscences, Zürich, Switzerland; 4 Applied Research and Development- Millipore Sigma, Bellefonte- PA, USA
FUN3-P02-Mo - Study of mass transfer phenomena in core-shell and sub-2µm fully porous chiral stationary phases for ultrafast high-performance enantioseparationsM. Catani1, O.H. Ismail2, S. Felletti1, M. Morbidelli3, F. Gasparrini2, A. Cavazzini11 University of Ferrara, Department of Chemical and Pharmaceutical Sciences, Ferrara, Italy; 2 “Sapienza” University of Rome, Department of Drug Chemistry and Technology, Rome, Italy; 3 Institute of Chemical and Bioengineering - ETH Zurich, Department of Chemistry and Applied Bioscences, Zurich, Switzerland
FUN3-P03-Mo - The effect of system band broadening in modern size exclusion chromatographyA. Goyon, J.L. Veuthey, D. Guillarme, S. FeketeUniversity of Geneva, Sciences, Geneva, Switzerland
77HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN3-P04-Mo - Mobility of analytes in binary solvents at nonpolar modified silica surfaces from molecular dynamics simulationsJ. Rybka1, A. Höltzel1, A. Seidel-Morgenstern2, U. Tallarek1
1 Philipps-Universität Marburg, Chemistry, Marburg, Germany; 2 Max-Planck-Institut für Dynamik komplexer technischer Systeme Magdeburg, Physical and Chemical Foundation of Process Engineering, Magdeburg, Germany
FUN 4 Stationary phases based on inorganic supportsFUN4-P01-Mo - Wide pore monolithic silica of various functionalization: Protein A, C18, C8 and C4, in high performance liquid chromatography for large molecule separationsE. Machtejevas1, B. Peters2, T. Kupfer2
1 Merck KGaA, Advanced Analytical, Darmstadt, Germany; 2 Merck KGaA, Analytical R&D, Darmstadt, Germany
FUN4-P02-Mo - Temperature-responsive molecular recognition chromatography using amino acid derived polymer modified silica beadsT. Nishimoto, H. KanazawaKeio University, Faculty of Pharmacy, Tokyo, Japan
FUN4-P03-Mo - Characterization of silica-based monolithic columns modified to mixed-mode stationary phase by phosphonium ionic liquidD. Moravcová1, J. Planeta1, A.W.T. King2, S.K. Wiedmer2
1 Institute of Analytical Chemistry of the CAS, Department of fluid phase separations, Brno, Czech Republic; 2 University of Helsinki, Department of Chemistry, Helsinki, Finland
FUN4-P04-Mo - Preparation and evaluation of silica capillary monolithic columns for HILIC separationsJ. Planeta, D. Moravcová, M. Roth, P. KarásekInstitute of Analytical Chemistry of the CAS v. v. i., Department of fluid phase separations, Brno, Czech Republic
FUN4-P05-Mo - Analysis of small pharmaceuticals and peptide mixtures using chemically stable merged inorganic/organic silica material in reversed phase chromatographyF. Limé1, E. Lundin2, C. Mazza2
1 AkzoNobel/Kromasil, RD&I, Bohus, Sweden; 2 AkzoNobel/Kromasil, Separation Products, Bohus, Sweden
FUN4-P06-Mo - Influence of zwitterion nature on chromatographic performance of HILIC stationary phasesA. Chernobrovkina, Y. Sedov, I. Kovalenko, A. Zatirakha, A. Smolenkov, O. ShpigunMoscow State University, Department of Chemistry, Moscow, Russian Federation
FUN 5 Supercritical fluid chromatographyFUN5-P01-Tu - Development and validation of a fast SFC method for the analysis of flavonoids in plant extractsY. Huang1,2, Z. Jiang1, M. Fillet2, J. Crommen2
1 Institute of Pharmaceutical Analysis, College of Pharmacy- Jinan University, Guangzhou, China; 2 Laboratory for the Analysis of Medicine, Department of Pharmaceutical Sciences- CIRM- University of Liege, Liege, Belgium
FUN5-P02-Tu - Analytical challenges associated with the separation and quantification of bioactive compounds from palm oil by ultra-high performance supercritical fluid chromatographyC. Santana1, L. Guedes2, I. Jardim3, M. Breitkreitz3, D. Rutledge4, J.L. Segundo Neto5, M. Beppu2, L. Melo3
1 UNIT, Process Engineering, Aracaju, Brazil; 2 UNICAMP, School of Chemical Engineering, Campinas, Brazil; 3 UNICAMP, Institute of Chemistry, Campinas, Brazil; 4 AGROPARISTECH, Laboratoire de Chimie Analytique, Paris, France; 5 UFPB, Chemistry, João Pessoa, Brazil
FUN5-P03-Tu - SFC-QqQ technology to understand metabolism of an achiral Drug to chiral metabolites in biological matricesR. Prabhakar Koiram1, T. Rajendra Prasad1, S. Joseph2, P. Kole1, M. Subramanian1, S. Rajagopalan2, M. Sinz1, S. Mandlekar1, M. Metzlaff3
1 Pharmaceutical Candidate Optimization- Biocon Bristol-Myers Squibb Research Center- Syngene International Limited, Bangalore, India; 2 Life Science Center- Agilent Technologies Inc, Bangalore, India; 3 Agilent Technologies, Germany
78 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN5-P04-Tu - Supercritical fluid chromatography with flexible injection volumes and highest precision on the Agilent 1260 Infinity II Analytical SFC SystemP. Hörth, E. Nägele, T. OrtmannAgilent Technologies, R&D and Marketing GmbH, Waldbronn, Germany
FUN5-P05-Tu - Pushing the efficiency of chiral super critical fluid chromatography to unexplored limits with sub 2-micron Whelk-O1 fully porous chiral particlesO.H. Ismail1, G.L. Losacco1, G. Mazzoccanti1, A. Ciogli1, C. Villani1, A. Cavazzini2, M. Catani2, S. Anderson3, F. Gasparrini11 University of Rome La Sapienza, Dipartimento Chimica e tecnologia del farmaco, Roma, Italy; 2 Università di Ferrara, Ferrara, Italy; 3 Regis Technologies, Morton Grove, USA
FUN5-P06-Tu - The power of selectivity and the strength to choose - chiral screening using an SFC / LC switching systemG. SchadShimadzu Europa GmbH, Analytical Business Unit, Duisburg, Germany
FUN5-P07-Tu - Development of new polymer-based column for supercritical fluid chromatographyY. Fujito, Y. HayakawaShimadzu Corporation, Global Application Development Center, Kyoto, Japan
FUN5-P08-Tu - Advantages of SFC-MS compared to LC-MS in the analysis of small moleculesR. Ludwig, S. BaumgartenShimadzu Europe GmbH, Customer Care Innovation & Product Support, Duisburg, Germany
FUN5-P09-Tu - Understanding the injection parameters of a new SFC autosamplerX. Wang, E. Naegele, T. OrtmannAgilent Technologies, Liquid Phase Separation Division, Waldbronn, Germany
FUN5-P10-Tu - Stretching ultra high performance supercritical fluid chromatography (UHPSFC) to the limit: Simultaneous analysis of vitamins with different physical-chemical propertiesM. Breitkreitz, F.H.P. Bruhn, L.V. de Melo, I.C.S.F. JardimChemistry Institute- University of Campinas UNICAMP, Analytical Chemistry, Campinas, Brazil
FUN5-P11-Tu - The limits of resolution in preparative SFC chiral separationsJ. Sadownik, C. van TilburgMercachem B.V., Analytical, Nijmegen, The Netherlands
FUN5-P12-Tu - Supercritical fluid chromatography with quadrupole-time-of-flight mass spectrometry for analysis of lignin-derived compoundsM. Sun, J. Prothmann, P. Spegél, M. Sandahl, C. TurnerLund University, Department of Chemistry, Lund, Sweden
FUN5-P13-Tu - Study of achiral selectivity of chiral columns in SFC: Application for impurity profiling of drugs candidatesE. Lemasson1, A. Raimbault1, S. Bertin2, F. Mauge2, P. Hennig2, E. Lesellier1, C. West1
1 ICOA, Chemistry, Orléans, France; 2 Institut de Recherches Servier, Chemistry, Suresnes, France
FUN5-P14-Tu - Development of photografted methacrylate-based chiral monolithic columns with a coating of cellulose tris(3,5-dimethyl phenyl carbamate) for capillary electrochromatographyR.N. Echevarría1, E.J. Carrasco-Correa2, J.M. Herrero-Martínez2
1 Universidad Nacional de La Plata, Facultad de Ciencias Exactas, La Plata, Argentina; 2 Universitat de Valencia, Analytical Chemistry, Burjassot, Spain
FUN5-P15-Tu - Comparison of ultra high performance supercritical fluid chromatography and ultra high performance liquid chromatography for pesticide multiresidue analysis in lettuce samplesM. Breitkreitz, K.P. de Lima, I.C.S.F. JardimChemistry Institute- University of Campinas UNICAMP, Analytical Chemistry, Campinas, Brazil
79HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN 6 Novel high-efficient separation mediaFUN6-P01-Tu - The superficially porous particles that were recently developed for separation of small molecules and large biomolecules are reviewedW. Chen1, A. Mack2
1 Agilent Technologies, Columns R&D, Wilmington, USA; 2 Agilent Technologies, Wilmington, USA
FUN6-P02-Tu - The important properties for an ideal stationary phaseO. Nakajima, I. SallayOSAKA SODA CO.- LTD., Osaka, Japan
FUN6-P03-Tu - Phosphopeptide enrichment via immobilized metal affinity chromatography using phosphonic acid functionalized capillary monolith as a stationary phase in a microfluidic systemD.D. Usta1,2, C. Kip3, K. Salimi3, O. Celikbicak4, A. Pinar5, B. Salih4, A. Tuncel3,6
1 Gazi University, Department Of Medical Biology And Genetics, Ankara, Turkey; 2 Istanbul Medeniyet University, Department Of Medical Biology, Istanbul, Turkey; 3 Hacettepe University, Chemical Engineering Department, Ankara, Turkey; 4 Hacettepe University, Chemistry Department, Ankara, Turkey; 5 Hacettepe University, Department Of Medical Biochemistry, Ankara, Turkey;
6 Hacettepe University, Division Of Nanotechnology And Nanomedicine, Ankara, Turkey
FUN6-P04-Tu - Hybrid stationary phases with retention independent separation performance in nano-hydrophilic interaction chromatographyC. Kip1, C. Demir1, A. Tuncel1,2
1 Hacettepe University, Chemical Engineering Department, Ankara, Turkey; 2 Hacettepe University, Division Of Nanotechnology And Nanomedicine, Ankara, Turkey
FUN6-P05-Tu - Method transfer considerations when transferring methods to sub 2 µm GFC columns for bioanalysisJ. Anspach, S. Rao, B. Rivera, L. Loo, I. Rustamov, T. FarkasPhenomenex, Research and Development, Torrance, USA
FUN6-P06-Tu - Peptide and oligonucleotide purification via IEX doped reverse phase chromatographyJ. Machielse, W. AndreaZeochem AG, Uetikon am See, Switzerland
FUN6-P07-Tu - Evaluating the advantage of higher heat conductivity of a recent core-shell diamond stationary phase particle in UHPLCM. Leśko1, D. Åsberg2, J. Samuelsson2, K. Kaczmarski1, T. Fornstedt2
1 Rzeszow University of Technology, Department of Chemical and Process Engineering, Rzeszow, Poland; 2 Karlstad University, Department of Engineering and Chemical Sciences, Karlstad, Sweden
FUN6-P08-Tu - Development of charged hybrid materials and their application in peptide separationY. Li1, O. Potter2, S.B. C.V.3, B. Richter1, H. Yin2, K. Killeen2
1 Agilent Technologies, ACG R&D, Wilmington, USA; 2 Agilent Technologies, ACG R&D, Santa Clara, USA; 3 Agilent Technologies India Pvt. Ltd., PLBC-Marketing, Bangalore, India
FUN6-P09-Tu - Alkanethiol functionalized organosilicon monoliths via one-pot thiol-methacrylate polymerization for nano-reversed phase chromatographyC. Demir1, C. Kip1, A. Kuban1, A. Tuncel1,2
1 Hacettepe University, Chemical Engineering, Ankara, Turkey; 2 Hacettepe University, Division of Nanotechnology And Nanomedicine, Ankara, Turkey
FUN6-P10-Tu - Investigation of column performance of monolithic silica capillary columns with very narrow column diameterT. Hara1, S. Futagami2, T. Bamba1, Y. Izumi1, W. de Malsche2, G. V. Baron2, G. Desmet2
1 Kyushu University, Medical Institute of Bioregulation, Fukuoka, Japan; 2 Vrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium
FUN6-P11-Tu - Novel pyridinium-based zwitter ionic polymer-grafted porous silica for HILIC stationary phaseM. Takafuji1, S. Sumon2, K. Sasahara1, M. Rahman2, H. Ihara1
1 Kumamoto University, Department of Applied Chemistry and Biochemistry, Kumamoto, Japan; 2 Dhaka University, Dhaka, Bangladesh
80 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN6-P12-Tu - A comprehensive study to the effects of mobile-phase composition on protein retention in hydrophobic interaction chromatographyE. Tyteca1, M. Tassi2, J. De Vos2, K. Cook3, X. Liu4, S. Eeltink2
1 University of Liège, Gembloux Agro-BioTech- Department of Agronomy- Bio-engineering and Chemistry- Analytical Chemistry, Gembloux, Belgium; 2 Vrije Universiteit Brussel, Chemical Engineering, Brussels, Belgium; 3 Thermo Fisher Scientific, Hemel Hempstead, United Kingdom; 4 Thermo Fisher Scientific, Sunnyvale, USA
FUN6-P13-Tu - Analytical selectivity enhancements that deliver improved resolution to enable identification of critical quality attributesL. Lloyd1, S.B. C.V.21 Agilent Technologies LDA UK Ltd, Marketing, Church Stretton, United Kingdom; 2 Agilent Technologies India Pvt. Ltd., Marekting, Bangalore, India
FUN6-P14-Tu - Improved size separation of peptides and small biomoleculesI. Salomonson, T. GranérGE Healthcare, Protein Purification and Analysis, Uppsala, Sweden
FUN6-P15-Tu - Novel through-porous particles applied to HPLC columnN. Ishizuka1, R. Takahashi2, R. Wada2, M. Taniguchi2, T. Yukiyama2, M. Miyashita2, K. Tsutsui2, N. Kuroda2, H. Kanezaki2, N. Shoji2, N. Kuriyama2
1 Emaus Kyoto Inc., R&D, Kyoto, Japan; 2 YMC Co.- Ltd., R&D Department, Kyoto, Japan
FUN6-P16-Tu - Improving the analysis of polar analytes with a novel HILIC phase on superficially porous particle LC columnsA. Mack, B. Long, A. Bivens, J. LinkAgilent Technologies Inc, Chemistries and Supplies Division, Wilmington Delaware, USA
FUN6-P17-Tu - Exploring effect of mesopore size on column performance of silica-based porous layered open tube capillary columnsT. Hara1, S. Futagami2, T. Bamba1, Y. Izumi1, W. De Malsche2, G. V. Baron2, G. Desmet2
1 Kyushu university, Medical Institute of Bioregulation, Fukuoka, Japan; 2 Vrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium
FUN 7 Electromigration techniquesFUN7-P01-Tu - Characterization of nanoparticles by means of capillary electrophoresisJ. Petr, D. Baron, A. ŠebestováPalacky University in Olomouc, Department of Analytical Chemistry, Olomouc, Czech Republic
FUN7-P02-Tu - Separation and sensitive detection of lanthanides by capillary electrophoresis and contactless conductivity detectionN. Öztekin, H.E. YelkenciTechnical University of Istanbul, Chemistry, Istanbul, Turkey
FUN7-P03-Tu - CE-LIF method development and validation for the determination of selected pterins in urine samplesM. Buszewska-Forajta1, S. Macioszek1, W. Grochocki1, J. Jacyna1, M. Markuszewski2, M. Matuszewski4, M.J. Markuszewski11 Medical University of Gdańsk, Department of Biopharamceutics and Pharmacodynamics, Gdańsk, Poland; 2 Medical University of Gdansk, Chair and Clinic of Urology, Gdańsk, Poland
FUN7-P04-Tu - New insights into head-column field amplified stacking of weak bases across a short water plugJ. Šesták1, W. Thormann2
1 Institute of Analytical Chemistry of the Czech Academy of Sciences v. v. i., Department of Fluid Phase Separations, Brno, Czech Republic; 2 University of Bern, Institute for Infectious Diseases - Clinical Pharmacology Laboratory, Bern, Switzerland
FUN7-P05-Tu - Electrolyte systems for analysis of very weak acids by anionic isotachophoresis with electrospray-ionization mass-spectrometric detectionZ. Malá, P. GebauerInstitute of Analytical Chemistry of the Czech Academy of Sciences- v.v.i., Electromigration Methods, Brno, Czech Republic
81HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN7-P06-Tu - Molecular sieving separation of biomolecules with PEG-hydrogel packed capillaries in capillary gel electrophoresisN. Nishimura, T. Naito, T. Kubo, K. OtsukaKyoto University, Material Chemistry, Kyoto, Japan
FUN7-P07-Tu - Development of highly sensitive methods for detection of damaged nucleotides by using CE enrichment coupled with on-line complexation followed by ESI-MS measurementY. Esaka1, K. Hisato1, T. Fujii1, B. Uno1, M. Torimura2, Y. Ishihama3, H. Murakami4, T. Hirokawa5
1 Gifu Pharmaceutical University, School of Medicine, Gifu, Japan; 2 Institute of Advanced Industrial Science and Technology, Tsukuba, Japan; 3 Graduate School of Pharmaceutical Science- Kyoto University, Kyoto, Japan; 4 Aichi Institute of Technology, Toyota, Japan; 5 Graduate School of Industry- Hiroshima University, Higashi-hiroshima, Japan
FUN7-P08-Tu - Designing of microfluidic-based capillary electrophoresis with on-line surface enhanced Raman spectroscopy detectionA. Tycova, R. Gerhardt, D. BelderUniversity of Leipzig, Institute of Analytical Chemistry, Leipzig, Germany
FUN7-P09-Tu - The next generation of capillary electrophoresis: CE-SDS instrument evaluation for protein analysisJ. Kahle, K.J. Maul, H. WätzigTU Braunschweig, Institute of Medicinal and Pharmaceutical Chemistry, Braunschweig, Germany
FUN7-P10-Tu - Estimation of effective charges and ionic mobilities of strongly basic antimicrobial peptides using capillary electromigration methodsT. Tůmová1,2, L. Monincová3, O. Nešuta2,4, V. Čeřovský4, V. Kašička1
1 Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Electromigration methods, Prague 6, Czech Republic; 2 University of Chemistry and Technology Prague, Faculty of Food and Biochemical Technology, Prague 6, Czech Republic; 3 Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Medicinal chemistry, Prague 6, Czech Republic; 4 Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Antimicrobial peptides, Prague 6, Czech Republic
FUN7-P11-Tu - Development of a separation technology for O6-benzylguanine and 8-oxo-O6-benzylguanine to study aldehyde oxidase by the use of capillary electrophoresis with UV detectionS. Huang, E. Adams, A. Van SchepdaelKU Leuven, Pharmaceutical analysis, Leuven, Belgium
FUN7-P12-Tu - Enantioseparation and assessment of racemization barriers of selected helquats and their derivatives by capillary electrophoresis using sulfated cyclodextrins as chiral selectorsP. Sazelova1, D. Koval1, L. Severa2, P.E. Reyes-Gutiérrez2, F. Teply2, V. Kasicka1
1 Institute of Organic Chemisty and Biochemistry of the CAS, Electromigration methods, Prague, Czech Republic; 2 Institute of Organic Chemisty and Biochemistry of the CAS, Helquat Chemistry and Biology, Prague, Czech Republic
FUN7-P13-Tu - The use of different types of reaction boundaries and their application in electrophoresisL. Janštová, E. Glovinová, J. PospichalMendel University- Brno, Chemistry and Biochemistry, Brno, Czech Republic
FUN7-P14-Tu - Separation of oligopeptides, nucleobases, nucleosides and nucleotides using capillary electrophoresis/electrochromatography with sol-gel modified inner capillary wallJ. Svobodova1, O. Kofroňová2, O. Benada2, V. Král3, I. Mikšík1
1 Institute of Physiology, Dpt. Analysis of Biol.Important Compounds, Praha 4, Czech Republic; 2 Institute of Microbiology, Laboratory of Molecular Structure Characterization, Praha 4, Czech Republic; 3 Institute of Chemical Technology, Department of Analytical Chemistry, Praha 6, Czech Republic
FUN7-P15-Tu - Development of a micellar electrokinetic capillary chromatography method for the determination of impurities in indomethacinP. Riasová, D. Mitlenerová, L. Pincová, P. Jáč, M. PolášekUniverzita Karlova- Farmaceutická fakulta Hradec Králové, Department of Analytical Chemistry, Hradec Králové, Czech Republic
82 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN7-P16-Tu - Comparison of GENTRANS and COMSOL Multiphysics for high-resolution dynamic computer simulation of electrophoresisS. Mikkonen1, H. Ekström2,3, W. Thormann1
1 University of Bern, Clinical Pharmacology Laboratory, Bern, Switzerland; 2 KTH Royal Institute of Technology, Chemical Engineering and Technology, Stockholm, Sweden; 3 COMSOL AB, Product Development- Electrochemistry, Stockholm, Sweden
FUN7-P17-Tu - Affinity capillary electrophoresis and quantum mechanical calculations applied to investigation of [Gly6]-antamanide binding with small cationsS. Pangavhane1, S. Böhm2, E. Makrlík3, P. Ruzza4, V. Kašička1
1 The Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, Electromigration Methods, Praha, Czech Republic; 2 University of Chemistry and Technology, Faculty of Food and Biochemical Technology, Prague, Czech Republic;
3 Czech University of Life Sciences, Faculty of Environmental Sciences, Prague, Czech Republic; 4 Institute of Biomolecular Chemistry of CNR, Department of Chemical Sciences, Padua, Italy
FUN7-P18-Tu - Determination of acidity constants and ionic mobilities of carborane-based carbonic anhydrase inhibitors by capillary electrophoresisV. Solinova1, V. Kasicka1, J. Brynda2, P. Rezacova2, V. Sicha3, J. Holub3, B. Gruner3
1 Institute of Organic Chemistry and Biochemistry of the CAS, Electromigration Methods, Prague, Czech Republic; 2 Institute of Organic Chemistry and Biochemistry of the CAS, Structural Biology, Prague, Czech Republic; 3 Institute of Inorganic Chemistry of the CAS, Deparment of Syntheses, Rez, Czech Republic
FUN7-P19-Tu - Two-cylinder capillary manufactured by etching with sub-/supercritical water as a tool for electrophoretic separationsP. Karásek, M. Horká, M. Roth, J. PlanetaInstitute of Analytical Chemistry of the CAS v. v. i., Department of fluid phase separations, Brno, Czech Republic
FUN7-P20-Tu - Hadamard transform capillary zone electrophoresis (HT-CZE): Benefits and limitations of a multiplexing technique on an unmodified standard CE systemS. Pallmann, A. Siegle, J. Steflova, O. TrappLudwig-Maximilians-University München, Faculty Chemistry and Pharmacy, München, Germany
FUN7-P21-Tu - Partial filling method and flow induced dispersion analysis - alternative methods for determination of stability constants to affinity capillary electrophoresisM. Ansorge, K. Ušelová, P. Dubský, M. RiesováCharles University, Department of Physical and Macromolecular Chemistry, Prague, Czech Republic
FUN7-P22-Tu - From HVLR to HVL function: Development of injection zones in capillary zone electrophoresisM. Ördögová, M. Dvořák, P. DubskýCharles University, Department of Physical and Macromolecular Chemistry, Prague, Czech Republic
FUN7-P23-Tu - Optimization of selected Cu free click reactions and their applicability in on-line labeling in CZEJ. Steflova1,2, G. Storch3, S. Wiesner4, O. Trapp2
1 Faculty of Science- Charles University in Prague, Department of Physical and Macromolecular Chemistry, Prague, Czech Republic; 2 Ludwig-Maximilians-Universität München, Department of Chemistry, Munich, Germany; 3 Yale University, Department of Chemistry, New Haven, USA; 4 Heidelberg University, Institute of Organic Chemistry, Heidelberg, Germany
FUN7-P24-Tu - Separation of FLEC diastereomers by CE vs. LC approaches in the context of neurometabolomicsR.C. Moldovan1,2, E. Bodoki2, A.C. Servais1, J. Crommen1, R. Oprean2, M. Fillet1
1 University of Liege, Laboratory for the Analysis of Medicines, Liege, Belgium; 2 "Iuliu Hatieganu" University of Medicine and Pharmacy Cluj-Napoca, Department of Analytical Chemistry, Cluj-Napoca, Romania
FUN7-P25-Tu - On-line monitoring of physiological processes by capillary electrophoresisP. TůmaCharles University, Third Faculty of Medicine, Department of Biochemistry, Prague 10, Czech Republic
FUN7-P26-Tu - Rapid method for diagnosis of methanol and ethylene glycol poisoning from blood samples by capillary electrophoresisP. Ďurč1,2, F. Foret1,3, P. Kubáň1,2,3
1 CEITEC Masaryk University, Department of Bioanalytical Instrumentation, Brno, Czech Republic; 2 Masaryk University, Department of Chemistry, Brno, Czech Republic; 3 Institute of Analytical Chemistry- Czech Academy of Sciences- v.v.i., Department of Bioanalytical Instrumentation, Brno, Czech Republic
83HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN7-P27-Tu - Capillary electrophoresis chiral separations: Mathematical approach to determine optimum chiral selector concentrationC. Lancioni, S. Keunchkarian, L.G. GagliardiUniversidad Nacional de La Plata y CONICET, Laboratorio de Investigación y Desarrollo de Métodos Analíticos- LIDMA., La Plata, Argentina
FUN7-P28-Tu - Microchip electrophoresis instrumentation for detection of biosignatures on future in situ planetary investigationsM. Mora1, N. Bramall2, F. Kehl1, P. Willis1
1 NASA Jet Propulsion Laboratory, Microdevices Laboratory, Pasadena, USA; 2 Leiden Measurement Technology LLC, Chief Executive Office, Sunnyvale, USA
FUN7-P29-Tu - Determination of underivatized amino acids by capillary zone electrophoresis with contactless conductivity detectionN. Öztekin, Ü. TüreyenTechnical University of Istanbul, Chemistry, Istanbul, Turkey
FUN 8 Separation techniques for ionic compoundsFUN8-P01-Tu - The serial RPLC-HILIC system for direct injection of high water content solutions to a HILIC column for the separation of polar and very polar compoundsS. Grosse, S. Veloutsou, T. LetzelTechnical University of Munich, Chair of Urban Water Systems Engineering, Garching, Germany
FUN8-P03-Tu - An investigation into the applicability of hydrophilic interaction chromatography for the co-analysis of some antibiotic and antiretroviral compoundsJ. Heaton1, N. Smith2, D. McCalley1
1 University of the West of England, Centre for Research in Biosciences, Bristol, United Kingdom; 2 King's College London, Analytical and Environmental Science Division, London, United Kingdom
FUN8-P04-Tu - Humic substances - analysis and characterization of operationally defined substances by HPLC with tandem multidetectionM. Hutta, R. Góra, E. Beňo, I. MordovinFaculty of Natural Sciences- Comenius University in Bratislava, Department of Analytical Chemistry, Bratislava, Slovakia
FUN8-P05-Tu - Development of a microfluidic ion chromatographic analyzer and application to trace analysis in Arctic ice coresS. Wouters1, J.L. Dores-Sousa1, J.L. Tison2, S. Eeltink1
1 Vrije Universiteit Brussel, Chemical Engineering, Brussel, Belgium; 2 Université Libre de Bruxelles, Faculty of Sciences- Laboratory of Glaciology, Brussels, Belgium
FUN8-P06-Tu - Chromatographic determination of pKa value of capecitabine with RPLC methodY.D. Daldal, İ.D. Nane, G. Alsancak, E. Çubuk DemiralaySuleyman Demirel University, Analytical Chemistry, Isparta, Turkey
FUN8-P07-Tu - Influence of external functional layer of anion-exchangers on their selectivity toward weakly retained organic acidsA. Zatirakha, A. Uzhel, A. Smolenkov, O. ShpigunLomonosov Moscow State University, Chemistry department, Moscow, Russian Federation
FUN 9 Separation mechanisms and structural effectsFUN9-P01-We - A comparison of the selectivity of solid-core CORTECS columns and fully porous columnsJ. Nguyen, T. SwannWaters Corporation, Technology Advancement, Milford- MA, USA
FUN9-P02-We - (U)HPLC basics and beyond: An evaluation of (U)HPLC operating parameters and their effect on chromatographic performanceK. Watanabe1, G. Schad2, M. Euerby3, T. Yamaguchi1, M. Tomita1
1 Shimadzu Corporation, LC Business Unit, Kyoto, Japan; 2 Shimadzu Europa GmbH, Duisburg, Germany; 3 Shimadzu UK Limited, Milton Keynes, United Kingdom
84 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN9-P05-We - Retention behavior of selected test substances in a diamond-based core-shell Flare HILIC column - preliminary investigationsJ. Kamińska1, M. Chutkowski1, L. Zapała2, W. Zapała1
1 Rzeszow University of Technology, Department of Chemical and Process Engineering, Rzeszow, Poland; 2 Rzeszow University of Technology, Department of Inorganic and Analytical Chemistry, Rzeszow, Poland
FUN9-P07-We - Stoichiometry and stability constants determination of β-cyclodextrin-drug complexesN. Maljurić, A. Protić, B. Otašević, J. Golubović, M. Zečević, J. KrmarUniversity of Belgrade- Faculty of Pharmacy, Department of Drug Analysis, Belgrade, Serbia
FUN9-P08-We - Simulation based investigation of the electroosmotic flow in capillary electrophoresis columns in the presence of forced convectionG. Jarvas1, M. Szigeti1, I. Molnár2, A. Guttman1
1 MTA-PE Translational Glycomics Research Group, MUKKI, Veszprem, Hungary; 2 Molnar-Institute for Applied Chromatography, Berlin, Germany
FUN9-P10-We - HILIC or ERLIC; could we distinguish them?J. Fiala1, M. Bittová1, J. Havliš1,2
1 Masaryk University, Chemistry, Brno, Czech Republic; 2 Masaryk University, National Centre for Biomolecules Research, Brno, Czech Republic
FUN9-P11-We - Quantitative structure – retention relationships for quinoline derivatives under conditions of reversed-phase liquid chromatographyN.A. Nekrasova, A.S. Savchenkova, S.V. KurbatovaSamara National Research University, Department of physical chemistry and chromatography- Samara Center for Theoretical Materials Science, Samara, Russian Federation
FUN9-P12-We - Analysis of packing microstructure and wall effects in a narrow-bore UHPLC columnA.E. Reising1, S. Schlabach2, V. Baranau1, D. Stoeckel1, U. Tallarek1
1 Philipps-Universität Marburg, Department of Chemistry, Marburg, Germany; 2 Karlsruhe Institute of Technology- 76344 Eggenstein-Leopoldshafen- Germany, Institute for Applied Materials IAM and Karlsruhe Nano Mikro Facility KNMF, Eggenstein-Leopoldshafen, Germany
FUN9-P13-We - Morphology based optimization of the packing protocol leading to ultra-efficient capillary columnsU. Tallarek1, A.E. Reising1, J.M. Godinho2, J.W. Jorgenson2
1 Philipps-Universität Marburg, Department of Chemistry, Marburg, Germany; 2 The University of North Carolina at Chapel Hill, Department of Chemistry, Chapel Hill, USA
FUN9-P14-We - Mixed mode stationary phases: Effect of mobile phase type and its ionic strength on separationL. Chrenková1, S. Schoebe2, M. Douša3, L. Nováková1
1 Charles University- Faculty of pharmacy, Department of analytical chemistry, Hradec Králové, Czech Republic; 2 Faculty of Chemistry and Earth Sciences- Friedrich Schiller University, Jena, Germany; 3 Zentiva- k.s. Praha, Praha, Czech Republic
FUN9-P15-We - New achiral strong cation-exchange type (SCX) and zwitterion-exchange type (ZWIX) stationary phases for the separation of basic analytes in different chromatographic modesD. Wolrab1, P. Fruehauf1, M. Kohout2, C. Gerner1
1 University of Vienna, Department of Analytical Chemistry, Vienna, Austria; 2 University of Chemical Technology Prague, Department of Organic Chemistry, Prague, Czech Republic
FUN9-P17-We - Probing the retention mechanism in hydrophilic interaction chromatography using saturation transfer difference nuclear magnetic resonance spectroscopyA. Xiamuxiding, K. IrgumUmeå University, Department of Chemistry, Umeå, Sweden
FUN9-P18-We - Experimental pKa's of Benzimidazole Anthelmintics by RPLCK. Poturcu, G. Alsancak, E. Cubuk DemiralayAnalytical Chemistry, Isparta, Turkey
85HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN9-P19-We - The influence of experimental conditions on chiral separation of anionic boron cluster compounds by liquid chromatographyR. Kučera1, M. Janetková1, B. Grüner2, R. Vespalec3
1 Charles University, Faculty of Pharmacy, Hradec Kralove, Czech Republic; 2 Academy of Science of the Czech Republic- v.v.i., Institute of Inorganic Chemistry, Řež near Prague, Czech Republic; 3 Academy of Science of the Czech Republic- v.v.i., Institute of Biophysics, Brno, Czech Republic
FUN9-P20-We - Assessment of retention behavior of heterogeneous group of antihistamines on two diol columnsJ. Terzić1, A. Stajić2, B. Jančić-Stojanović2
1 Medicines and Medical Devices Agency of Serbia, Pharmaceutical department, Belgrade, Serbia; 2 University of Belgrade- Faculty of Pharmacy, Department of Drug Analysis, Belgrade, Serbia
FUN9-P21-We - Determination of dissociation constant for R- and S-isomers of cefpodoxime by using RPLC MethodS. Budak, C. Çakır, K. Poturcu, G. Alsancak, E. Cubuk DemiralayAnalytical Chemistry, Isparta, Turkey
FUN9-P22-We - Instrumental parameters that affect method transfer in UHPLC separationsF. Steiner, M. Gruebner, S. Fabel, A. Manka, S. Patzelt, M. MartinThermo Fisher Scientific, Chromatography and Mass Spectrometry Division, Germering, Germany
FUN9-P23-We - Peptide retention time prediction in HILIC: Comparison of separation selectivity between bare silica and bonded stationary phases using ~40,000 peptide datasetsO. Krokhin1, V. Spicer2
1 University of Manitoba, Internal Medicine, Winnipeg, Canada; 2 University of Manitoba, Manitoba Centre for Proteomics and Systems Biology, Winnipeg, Canada
FUN 10 Organic polymer monolithic and particular materialsFUN10-P01-We - A novel PMOXA/PAA mixed brush with switchable properties toward on-line concentration of protein in capillary electrophoresisY. Wang, X. Liu, C. PanUniversity of Science and Technology of China, Department of Polymer Science and Engineering, Hefei, China
FUN10-P02-We - Strategies for the preparation of metal-organic framework/polymer hybrid beads and monoliths and their applications as sorbents for sample preparationF. Maya Alejandro, G. Turnes palomino, V. CerdàUniversitat de les Illes Balears, Department of Chemistry, Palma de Mallorca, Spain
FUN10-P03-We - Preparation and evaluation of a novel choline phos-phate functionalized polymeric monolith for hydro-philic interaction chromatographyQ. Wang, K. Peng, H. Jin, J. Crommen, Z. JiangJinan University, college of pharmacy, Guangzhou, China
FUN10-P04-We - Covalently-bonded hyperbranched anion-exchangers for ion chromatographyA. Uzhel, A. Gorbovskaja, A. Borodina, A. Zatirakha, A. Smolenkov, O. ShpigunMoscow State University, chemistry department, Moscow, Russian Federation
FUN10-P05-We - Incorporation of single-walled carbon nanohorns in methacrylate monoliths for nano liquid chromatographyB. Fresco Cala1, E.J. Carrasco Correa2, S. Cárdenas Aranzana1, J.M. Herrero Martínez2
1 University of Córdoba, Analytical Chemistry, Córdoba, Spain; 2 University of Valencia, Analytical Chemistry, Valencia, Spain
FUN10-P06-We - Enhancing the capabilities of electrochemical detection in HPLC-ED with capillary monolithic columnsR. Metelka1, M. Komendová1, J. Urban2
1 University of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic; 2 Masaryk University, Department of Chemistry, Brno, Czech Republic
86 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN10-P07-We - Photografting of fluoropolymer tubes for the preparation of organic monolithic columnsG. Ramis-Ramos1, M. Catalá-Icardo2, S. Torres-Cartas2, S. Meseguer-Lloret2, C. Gómez-Benito2, E.F. Simó-Alfonso1, J.M. Herrero-Martínez1
1 University of Valencia, Analytical Chemistry, Burjassot, Spain; 2 Universitat Politècnica de Valencia, Research Institute for Integrated Management of Coastal Areas, Grao de Gandía- Valencia, Spain
FUN10-P08-We - Studying the effect of monolith porosity on the analysis of nucleic acids using ion pair reversed phase and non-retentive HPLCA.W. Kung1, P. Clarke2, P.M. Kilby3, D.E. Portwood2, M.J. Dickman1
1 University of Sheffield, Chemical & Biological Engineering, Sheffield, United Kingdom; 2 Syngenta, Product Characterisation, Bracknell, United Kingdom; 3 Syngenta, Chemistry, Bracknell, United Kingdom
FUN10-P09-We - Zeolitic imidazolate framework-8-coated solid-phase microextraction arrow in the extraction of aminesH. Lan, T. Rönkkö, E. Parshintse, K. Hartonen, M.L. RiekkolaUniversity of Helsinki, Department of Chemistry, Helsinki, Finland
FUN10-P10-We - Surface modification of hybrid organo-silica monolithic capillary columns: Photografting vs. “one-pot”Z. Zajickova1, T. Sabol1, Z. Rodriguez1, T. Silva Campos1, L. Narciso Meirelles1, D. Britsch1, F. Svec2
1 Barry University, Physical Sciences, Miami Shores, USA; 2 Beijing University of Chemical Technology, College of Life Science and Technology, Beijing, China
FUN10-P12-We - Preparation of phenylboronic acid functionalized-polyhedral oligomeric siloxane monolithic column via one-pot approach for nano liquid chromatography of small moleculesC. Kip1, C. Demir1, G. Nedjip1, A. Tuncel1,2
1 Hacettepe University, Chemical Engineering Department, Ankara, Turkey; 2 Hacettepe University, Division of Nanotechnology and Nanomedicine, Ankara, Turkey
FUN 11 Thermodynamics and separation mechanisms in LCFUN11-P01-We - Estimation of axial variation of eluent properties using isenthalpic plotsE. Farsang, M. Surguta, K. HorváthUniversity of Pannonia, Analytical Chemistry, Veszprém, Hungary
FUN 12 Advances in stationary phasesFUN12-P01-We - Enantioseparation of 4C substituted pyrrolidine-2-ones on polysaccharide type coated chiral stationary phasesT. Upmanis1, N. Orlova2, M. Vorona2, H. Kazoka1
1 Latvian Institute of Organic Synthesis, Laboratory of Chromatography, Riga, Latvia; 2 Latvian Institute of Organic Synthesis, Laboratory of Organometallic Chemistry, Riga, Latvia
FUN12-P02-We - Induction of chiral recognition with lipid nano-domains produced by polymerization for high performance chiral separationY. Okamoto, K. Yusuke, S. Keishi, U. HiroshiOsaka University, Div. of Chemical Engineering Grad.Sch. of Engineering Science, Toyonaka-Osaka, Japan
FUN12-P03-We - Importance of hydrogen bonding on deuterium isotope effects in liquid chromatographic separationE. Kanao, T. Naito, T. Kubo, K. OtsukaKyoto University, Material Chemistry, Kyoto, Japan
FUN12-P04-We - Immobilization of chondroitin sulfate a into monolithic epoxy column for chiral separationRatih, M. Asmari, S. Öner, S. El DeebTechnical University Braunschweig, Institute of Medicinal and Pharmaceutical Chemistry, Braunschweig, Germany
87HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN12-P05-We - From sub 2-micron fully porous teicoplanin-based zwitterionic chiral stationary phases to 2-micron superficially porous ones: What can we expect in terms of efficiency gain?M. De Martino1, O.H. Ismail1, M. Antonelli1, A. Ciogli1, M. Catani2, D. Bell3, A. Cavazzini2, C. Villani1, F. Gasparrini11 Sapienza- University of Rome, Dipartimento Chimica e Tecnologia del farmaco, Roma, Italy; 2 Università di Ferrara, Dipartimento di Scienze Chimiche e Farmaceutiche, Ferrara, Italy; 3 Milliporesigma, Sigma-Aldrich/Supelco, Bellefonte, USA
FUN12-P06-We - Unique chemically modified carbohydrate based chiral stationary phases to improve chiral separationsM. Przybyciel, D. KohlerES Industries, HPLC Columns, West Berlin, USA
FUN12-P07-We - Development and characterization of HILIC stationary phases modified with polymers possessing chiral group based on cysteine derivativesA. Taniguchi, T. IkegamiKyoto Institute of Technology, Faculty of Molecular Chemistry and Engineering, Kyoto, Japan
FUN12-P08-We - Enantioselective HPLC separation of amino acids. Comparison of different types of chiral stationary phases and chromatographic separation modesK. Hroboňová, A. LomenovaFaculty of Chemical and Food Technology- Slovak University of Technology in Bratislava, Institute of Analytical Chemistry, Bratislava, Slovakia
FUN 13 Data analysis, validation and chemometricsFUN13-P01-Mo - A highly sensitive microwave flow detector for gradient elution liquid chromatographyD. Ye1, W. Wang2, F. Chen2, P. Wang1
1 Clemson University, Electrical and Computer Engineering, Clemson, USA; 2 Clemson University, Food- Nutrition and Packaging Sciences, Clemson, USA
FUN13-P02-Mo - Determination of phenantrene metabolites in milk using second and third order multivariate HPLC- fluorimetric signalsE. Martin Tornero, I. Duran Martin-meras, A. Munoz De La Pena Castrillo, A. Espinosa MansillaUniversity of Extremadura, Analytical Chemistry and Research Institute on Water- Climate Change and Sustainability IACYS, Badajoz, Spain
FUN13-P03-Mo - About the use of prediction and content tolerance intervals in modern HPLC/UHPLC assay methods validationJ.M. Roussel1, M. Righezza2
1 Analytical Methods Development and Validation, Consultant, MACON, France; 2 Aix-Marseille Université, MARSEILLE, France
FUN13-P04-Mo - Quantitative structure–retention relationships modelling of aripiprazole and its impurities in micellar liquid chromatography using artificial neural networkJ. Krmar, B. Otašević, A. Protić, J. Golubović, N. Maljuric, M. ZecevicFaculty of Pharmacy- University of Belgrade, Department for Drug Analysis, Belgrade, Serbia
FUN13-P05-Mo - Gradient design for chromatography using multi-scale optimizationJ.R. Torres-Lapasió1, S. López-Ureña2, R. Donat2, M.C. García-Alvarez-Coque1
1 University of Valencia, Analytical Chemistry, Burjassot Valencia, Spain; 2 University of Valencia, Department of Mathematics, Burjassot, Spain
FUN13-P06-Mo - Assisted baseline subtraction in complex chromatograms using the BEADS algorithmJ.A. Navarro-Huerta1, S. Lopez-Ureña2, J.R. Torres-Lapasio1, M.C. Garcia-Alvarez-Coque1
1 University of Valencia, Analytical Chemistry, Burjassot Valencia, Spain; 2 University of Valencia, Department of Mathematics, Burjassot, Spain
88 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN13-P07-Mo - SIFT-MS spectra as an alternative for GC-MS chromatograms to classify healthy, asthmatic and cystic- fibrosis breath samples of childrenK. Segers1, A. Slosse1, J. Viaene1, M. Bannier2, K. Van de Kant2, E. Dompeling2, J. Vercammen3, Y. Vander Heyden1
1 Vrije Universiteit Brussel, Department of Analytical Chemistry and Pharmaceutical Technology- Department of Pharmaceutical Chemistry and Drug Analysis, Jette, Belgium; 2 Maastricht Universitair Medisch Centrum +, Dept of Pediatric Pulmonology, Maastricht, The Netherlands; 3 Interscience, Louvain-la-Neuve, Belgium
FUN13-P08-Mo - Compatibility visualization of aqueous pH with binary organic composition by statistical grid modeling of retention kinetics: A method for optimized reversed phase UHPLC separationT. Sasaki1, T. Toshimasa2
1 Analytical and Quality Evaluation Research Laboratories, Pharmaceutical Technolgoy Unit, Hiratsuka- Kanagawa, Japan;
2 Laboratory of Analytical and Bio-Analytical Chemistry, School of Pharmaceutical Sciences- University of Shizuoka, Shizuoka City- Suruga-Ku- Shizuoka, Japan
FUN13-P09-Mo - Application of quality by design to optimize LC analysis of drugs and their synthetic impurities: Case study for ticagrelorN. Wingert, J. Ellwanger, L. Bueno, C. Garcia, M. Steppe, E.E. SchapovalFederal University of Rio Grande do Sul, Laboratory of Pharmaceutical Quality Control, Porto Alegre, Brazil
FUN13-P10-Mo - The potential of under 250 nm deep UV-LEDs in chemical analysis: 235 nm UV-LED photometric detection in capillary liquid chromatographyY. Li1, P. Nesterenko1, B. Paull1, R. Stanley2, M. Macka1
1 University of Tasmania, School of Physical Sciences and Australian Centre for Research on Separation Science ACROSS, Hobart, Australia; 2 University of Tasmania, Centre for Food Innovation, Launceston, Australia
FUN13-P12-Mo - Experimental design and measurement error in drug-protein binding studiesM.O. Stein1, H. Wätzig1, M. Mozafari Torshizi1, F. Steinicke1, R. Haselberg2
1 University of Brunswick – Institute of Technology, Institute of Medicinal and Pharmaceutical Chemistry, Braunschweig, Germany; 2 Vrije Universiteit Amsterdam, Division of BioAnalytical Chemistry, Amsterdam, The Netherlands
FUN13-P13-Mo - Retention time prediction by LSS parameters and mapping of effective gradient: Synthesis of calibration standards and errors or predictionC.E. Jensen, N.J. Nielsen, J.H. ChristensenUniversity of Copenhagen, plant and environmental science, Copenhagen, Denmark
FUN13-P14-Mo - PARAFAC2 curve resolution in LC-MS-based study of the metabolomic response of Brassica napus L to glyphosateA. Andersen, M.B. Kristiansen, G. Tomasi, N.J. Nielsen, J.H. ChristensenUniversity of Copenhagen, Department of Plant and Environmental Sciences, Frederiksberg C, Denmark
FUN13-P15-Mo - Peak deconvolution analysis with photodiode array detectorD. Fujimura1, T. Yanagisawa2, T. Yamaguchi2, K. Watanabe1, K. Horie3, T. Kato4, S. Arase4
1 Shimadzu Corporation, LC Business Unit- Life Science Business Departiment- Analytical & Measuring Instruments Division, Kyoto, Japan; 2 Shimadzu Corporation, Life Science Business Departiment- Analytical & Measuring Instruments Division, Kyoto, Japan; 3 Eisai Co.- Ltd., Translational Medicine Department, Ibaraki, Japan; 4 Eisai Co.- Ltd., Formulation Research- PST CFU- Medicine Development Center, Gifu, Japan
FUN13-P16-Mo - Automated targeted screening of leachables in pharmaceutical QC labs using an Agilent Single Quadrupole LC/MS system and controlled by OpenLAB CDSS. Lateef, M. MetzlaffAgilent Technologies, Marketing, Bangalore, India
FUN13-P17-Mo - Analyzing chromatographic data using multilevel (hierarchical) modelsP. WiczlingMedical University of Gdańsk, Department of Biopharmaceutics and Pharmacodynamics, Gdańsk, Poland
FUN13-P18-Mo - Quality by design approach in the development of a stability indicating method for determination of apixaban and its related impuritiesJ. Ellwanger, N. Wingert, E. Shapoval, M. SteppeFederal University of Rio Grande do Sul, Laboratory of Pharmaceutical Quality Control, Porto Alegre, Brazil
89HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN13-P19-Mo - IntelliXtract 2.0: Simplified intelligent component extraction and detectionE. Kolovanov, R. Lee, V. Lashin, A. Paramonov, A.M. Smith, T. SalbertAdvanced Chemistry Development- Inc., Software Development, Toronto, Canada
FUN13-P20-Mo - Quality by design throughout the lifecycle of an analytical procedure demonstrated by an example for a purity method of a drug productA. SchmidtChromicent GmbH, Quality Unit, Berlin, Germany
FUN 14 Ultra-high resolution separationsFUN14-P01-Mo - Identification and monitoring leachables from single-use bags (SUBs) for mammalian cells culture by dispersive liquid-Liquid microextraction (DLLME) followed by UHPLC-QToF-MSN. Dorival-Garcia, J. BonesNIBRT, Characterisation and Comparability Laboratory, Dublin, Ireland
FUN14-P02-Mo - Some hint on how to make a standard UHPLC column with + 300 000 theoretical plates/meterN. Nagae1, T. Tsukamoto1, H. Svennberg2
1 ChromaNik Technologies Inc, R&D, Osaka, Japan; 2 Biotech AB, Innovation, Onsala, Sweden
FUN14-P03-Mo - The analysis of polar ionic pesticides by ion-exchange chromatography tandem mass spectrometry: The possible solution to a longstanding problematic analysis?J. Madden1, R. Fussell2, S. Adams3, J. Guest3, J. Beck4, F. Schoutsen5, S. Guazzotti11 Thermo Fisher Scientific, Sunnyvale, USA; 2 Thermo Fisher Scientific, Hemel Hempstead, United Kingdom; 3 Fera Science Ltd., York, United Kingdom; 4 Thermo Fisher Scientific, San Jose, USA; 5 Thermo Fisher Scientific, Breda, The Netherlands
FUN14-P04-Mo - Gel permeation chromatography with reduced column dimensions for industrial applicationsH. Eghbali1, A. Schweizer-Theobaldt1, R. Salome1, M. Pursch2, D. Meunier3
1 The Dow Chemical Company, Analytical Sciences, Hoek, The Netherlands; 2 The Dow Chemical Company, Analytical Sciences, Stade, Germany; 3 The Dow Chemical Company, Analytical Sciences, Midland, USA
FUN14-P05-Mo - Study of retention behavior of bioactive macromolecules in ultrahigh pressure liquid chromatographyE. Farsang, S. Horváth, K. HorváthUniversity of Pannonia, Veszprém, Hungary
FUN14-P06-Mo - Method optimization and validation for determination of cetirizine with reversed phase liquid chromatographic methodİ.D. Nane1, E. Çubuk DemiralaySuleyman Demirel University, Analytical Chemistry, Isparta, Turkey
FUN14-P08-Mo - Automating mobile phase pH for peptide mapping for LC-UV-MS methodsA. Dlugasch, P. McConville, J. SimeoneWaters Corporation, Systems Effectiveness Lab, Milford, USA
FUN14-P09-Mo - A SE-UHPLC method for routine characterization of a variety of different MAb formats was developed and implemented in GMP release analytics and stability testingM. Leiss, R. Ruppert1 Roche Diagnostics GmbH, Pharma Development Analytics, Penzberg, Germany
FUN14-P10-Mo - Comparison of HPLC and UHPLC analysis of polymer additives with photo diode array and mass detectionI. Francois1, H. Boiteux1, J.M. Plankeele1, J. Gough2, M. Twohig2, M. Jones3
1 Waters Corporation, Chemical Materials, En Yvelines Cedex, France; 2 Waters Corporation, Chemical Materials, Milford, USA;
3 Waters Corporation, Chemical Materials, Wilmslow, United Kingdom
90 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
FUN14-P11-Mo - Application of UPLC/MS/MS to the analysis of bio active compounds in apples and cherriesA. Horna1, K. Vynuchalova2, B. Hrvolova2, V. Vorisek3
1 RADANAL & Tomas Bata University in Zlin, Institute of Nutrition and Diagnostics, Pardubice, Czech Republic; 2 RADANAL, Institute of Nutrition and Diagnostics, Pardubice, Czech Republic; 3 RADANAL & Faculty Hospital Hradec Kralove Charles Unversity Prague, Institute of Nutrition and Diagnostics, Pardubice, Czech Republic
FUN14-P12-Mo - The chromatographic behavior of the PFP fused-core phases in the separation of ten anthocyaninsE.Y. Zhao1,2, K. Xue1, X. Jin1, H. Yue2, Y. Li11 Welch Materials Zhejiang- Inc., Research and Development, Jinhua, China; 2 Zhejiang Normal University, Institute of Physical Chemistry, jinhua, China
FUN14-P13-Mo - Fast calibration and bracketing of GPC/SEC separations as a means to improve data confidenceB. OkandejiWaters Corporation, Consumables Product Management, Milford, USA
FUN14-P14-Mo - Considerations for maximizing the efficiency benefits of sub-2-µm solid core particlesM. DeLoffiWaters Corporation, Consumables R&D, Milford, USA
FUN14-P15-Mo - A high-throughput method for the determination of 5-nitroimidazoles in fish roe samples combining salting-out assisted liquid/liquid extraction and UHPLC-MS/MSA.M. Garcia-Campaña, M. Hernández-Mesa, C. Cruces-BlancoFacultad De Ciencias, Química Analítica, Granada, Spain
FUN14-P16-Mo - Graphene/Fe3O4 nanocomposite based dispersive magnetic solid phase extraction coupled with UHPLC-PDA for simultaneous determination of NSAIDs in human plasma and urineV. Ferrone1, N. De Luca1, M. Carlucci2, A. Fontana1, V. Ettorre1, G. Carlucci11 University "G.d'Annunzio", Pharmacy, Chieti, Italy; 2 University "G.d'Annunzio", Department of Oral- Medical and Biotechnological sciences, Chieti, Italy
FUN14-P17-Mo - Synthesis and application of graphene/Fe3O4 magnetic nanocomposite as efficient sorbent for the UHPLC-PDA determination of mytomicin C and 5-fluorouracil in human plasmaG. Carlucci1, E. Milanetti2, S. Guadagni3, P. Palumbo4, A. Fontana1, V. Ettorre1, S. Miceli1, L. Di Marco1, V. Ferrone1, M. Carlucci51 University "G.d'Annunzio", Pharmacy, Chieti, Italy; 2 University "La sapienza", Physic, Roma, Italy; 3 University of L'Aquila, Applied Clinical Sciences and Biotechnology, L'Aquila, Italy; 4 University of L'Aquila, Live- Healt and Environmental Sciences, L'Aquila, Italy; 5 University "G.d'Annunzio", Oral- Medical and Biotechnological Sciences, Chieti, Italy
Program track Hyphenations (HYP)HYP 1 Ion mobility in LC/MSHYP1-P01-Mo - Unified pH of LC mobile phasesA. Heering1, L. Jalukse2, J. Liigand1, A. Kruve1, D. Himmel3, I. Krossing3, M. Rosés4, I. Leito1
1 University of Tartu, Institute of Chemistry, Tartu, Estonia; 2 TBD-Biodiscovery, Tartu, Estonia; 3 Albert-Ludwigs-Universität Freiburg, Institute for Inorganic and Analytical Chemistry and Freiburger Materialforschungszentrum, Freiburg, Germany;
4 Universitat de Barcelona, Departament de Química Analítica, Barcelona, Spain
HYP1-P02-Mo - Ion mobility spectrometry (IMS) combined with UPLC/MS for metabolic phenotyping: Effects of column length, gradient duration and IMS on metabolite detectionP. Rainville1, I. Wilson2, R. Plumb2
1 Waters Corporation, Scientific Operations, Milford, USA; 2 Imperial College London, London, United Kingdom
91HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP1-P03-Mo - Analysis of a Chinese herb formulation with HPLC and high resolution IM-qTOF-MJ. Klein, P. Shrestha, L. Morguet, O. SchmitzUniversity Duisburg-Essen, Applied Analytical Chemistry, Essen, Germany
HYP1-P04-Mo - High resolution trapped ion mobility mass spectrometry analysis of isomeric compoundsS. Meyer1, D. Vláčil21 Bruker Daltonik GmbH, Applications development, Bremen, Germany; 2 Bruker s. r. o., Sales And Application, Brno, Czech Republic
HYP 2 Ion suppression and matrix-effects in separation – MSHYP2-P01-Mo - Overcoming matrix effect challenges in multi class, multi residue LC/MS/MS analysis via biocompatible solid phase micro extraction (BioSPME)S. Smith, E. Barrey, D. Bell, C. AurandMilliporeSigma, Bellefonte, USA
HYP2-P02-Mo - Selectivity evaluation using the co-feature ratio in LC/MS metabolomics: Comparison of HILIC columns performance for the analysis of plasma, urine and cell extractsA. Elmsjö1, M. Engskog1, J. Haglöf1, I. Erngren1, M. Nestor2, T. Arvidsson3, C. Pettersson1
1 Uppsala University, Medicinal Chemistry, Uppsala, Sweden; 2 Uppsala University, Department of Immunology- Genetics and Pathology, Uppsala, Sweden; 3 Medical Products Agency, Uppsala, Sweden
HYP2-P03-Mo - The differences in matrix effects between supercritical fluid chromatography and reversed phase liquid chromatography coupled to ESI/MS analyzing blood plasmaA. Svan1, M. Hedeland1,2, T. Arvidsson1,3, C. Pettersson1
1 Division of Analytical Pharmaceutical Chemistry, Medicinal Chemistry, Uppsala, Sweden; 2 National Veterinary Institute SVA, Chemistry- Environment and Feed Hygiene, Uppsala, Sweden; 3 Medical product Agency- Sweden, Uppsala, Sweden
HYP2-P04-Mo - An investigation into the degree of ion suppression caused by column bleed using modern LC-MS compatible columnsT. Edge, L. BevanAgilent Technologies, Research and Development, Shrewsbury, United Kingdom
HYP 3 Separation – high-resolution MSHYP3-P01-Mo - High resolution LC/MS separation and characterization of chemoenzymatic site-specific engineered antibody-drug-conjugates (ADCS)S. Lin1, T. Zhang2, B. Agnew3, J. Josephs2, X. Liu1
1 Thermo Fisher Scientific, R&D, Sunnyvale- CA, USA; 2 Thermo Fisher Scientific, LSMS, San Jose- CA, USA; 3 Thermo Fisher Scientific, Life Science Group, Eugene-OR, USA
HYP3-P02-Mo - Novel ways to directly introduce salt based chromatography techniques of SEC and IEX of biopharmaceutical proteins into high resolution mass spectrometryK. Cook1, J. Bones2
1 EU Biopharma Support Specialist, Thermo Fisher Scientific, Hemel Hempstead, United Kingdom; 2 National Institute for Bioprocessing Research and Training (NIBRT), Blackrock, Ireland
HYP3-P03-Mo - HPLC-QTOF-MS analysis of the esterification and amidization of complex ammonium branched chain carboxylate salt mixturesL.J. Bostelaar1, W.F. Dong2, S. Ma2, L.B. Xin3
1 Vishay BCcomponents B.V., Aluminum Sub-Division, Zwolle, The Netherlands; 2 HEC, R&D Center Aluminum Products Division, Dongguan, China; 3 HEC, R&D Center Generics Division, Dongguan, China
HYP3-P04-Mo - Impurity profiling of commercial Poly (ethylene glycol) methyl ether methacrylate macro monomer using LC-ELSD/LC-MSR. Salome, M. Bashir, M. Van Engelen, H. EghbaliDow Benelux, Analytical Sciences, Terneuzen, The Netherlands
92 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP3-P05-Mo - Comparison of ultra-high performance liquid chromatography and supercritical fluid chromatography methods for analysis of photoinitiators as potential food contaminantsL. Borovcova1, V. Pauk1, J. Thacker2, L. Bai2, K.A. Schug1, K. Lemr1
1 Faculty of Science Palacký University, Analytical Chemistry-RCPTM, Olomouc, Czech Republic; 2 Department of Chemistry & Biochemistry- The University of Texas at Arlington, Arlington, USA
HYP3-P06-Mo - Quantification of steroid hormones in plasma using a surrogate calibrant approach and HPLC-HR-MS/MS with SWATH-AcquisitionB. Drotleff1, M. Hallschmid2, M. Lämmerhofer1
1 University of Tuebingen, Pharmaceutical Bio-Analysis, Tuebingen, Germany; 2 University of Tuebingen, Institute for Medical Psychology and Behavioural Neurobiology, Tuebingen, Germany
HYP3-P07-Mo - Trattinnickia rhoifolia extract profile and biomarkers determined by HRGC-MS/MS and UPLC-MS/MS for leishmaniasis treatmentA.A. de Souza1, M.B. Almeida1, T.B. Madeira1, L.S. Watanabe1, J.L.R. de Paula1, E.C. Meurer2, S.A. Nilton3, A.M. Monteiro1, L.A. Marques4, C. Emanuel4, S.L. Nixdorf1
1 Universidade Estadual de Londrina, Chemistry, Londrina, Brazil; 2 Universidade Federal do Paraná Jandaia do Sul, Chemistry, Jandaia do Sul, Brazil; 3 Universidade Estadual de Londrina, Pharmaceutical Sciences, Londrina, Brazil; 4 Instituto de Química de São Carlos - Universidade de São Paulo, Chemistry, São Carlos, Brazil
HYP3-P08-Mo - Development a novel LC-MS/MS method for simultaneous quantification of sofosbuvir and daclatasvir combined dosage form in human plasma: Application to pharmacokinetic studyA. Abdel-Megied1, O. Abdalla2, A. Gouda3
1 Faculty of Pharmacy- Kafrelsheikh University, Pharmaceutical Analytical Chemistry, Kafrelsheikh city, Egypt; 2 Faculty of Pharmacy- Badr University in Cairo BUC- Badr City- Cairo- Egypt, Pharmaceutical Chemistry Department-, Egypt; 3 Zi-diligence Research Center- Al-Mokattam- Cairo- Egypt
HYP3-P09-Mo - Simultaneous identification of trace organic impurities in purified terephthalic acid by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometryY. Guo, Y. Zhang, C. Wang, Z. PengShanghai Research Institute of Petrochemical Technology- SINOPEC, Characterization and Standardization Department, Shanghai, China
HYP3-P10-Mo - After gulf war oil spill, what are left in the contaminated soil from oil lake? - molecular level investigation with preparative HPLC and ultrahigh resolution mass spectrometryE. Cho1, G. Kang2, S. Kim1
1 Kyungpook National University, Chemistry, Deagu, Republic of Korea; 2 Hankuk University of Foreign Studies, Environmental Sciences, Yongin-si- Kyunggi-do, Republic of Korea
HYP3-P11-Mo - Native ion exchange chromatography coupled directly to Orbitrap mass spectrometry allows surface charge discrimination and online detection of intact proteinsA. Bailey1, G. Han2, W. Sandoval2, J. Josephs1
1 Thermo Fisher Scientific, Life Sciences BU- Chromatography and Mass Spectrometry Division, San Jose, USA; 2 Genentech, Department of Microchemistry- Proteomics and Lipidomics, South San Francisco, USA
HYP 4 Multidimensional chromatography and MS couplingHYP4-P01-Mo - Enhancing analytical confidence and detection limits for IC and LC applications by coupling them to single quadrupole mass spectrometryA. Semyonov, S. Guazzotti, N. SantiagoThermo Fisher Scientific, Analytical Instrumentation Group, Austin, USA
HYP4-P02-Mo - Development of 2-dimensional liquid chromatography-ion trap mass spectrometry for online microextraction, separation and analysis of ionophore coccidiostat residues in chicken eggsC. Cheng1, K.C. Chang2
1 Chung Yuan Christian University, Department of Chemistry, Taoyuan, Taiwan- Province of China; 2 Agricultural Technology Research Institute, Department of Animal Science and Technology, Miaoli County, Taiwan- Province of China
93HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP4-P03-Mo - Development of LCxLC-UV/MS platform as analytical strategy for the analysis of pharmaceutical compoundsM. Iguiniz1, E. Corbel2, N. Roques2, F. Rouviere1, S. Heinisch1
1 Insitut des Sciences Analytiques, Villeurbanne, France; 2 Oril Industrie, Bolbec, France
HYP4-P04-Mo - Liquid chromatography with apci and saldi mass spectrometry detection using silver nanoparticles in cholesteryl esters analysisV. Roblova1, M. Lísa2, J. Preisler1,3
1 Masaryk University, Department of Chemistry, Brno, Czech Republic; 2 University of Pardubice, Faculty of Chemical Technology, Pardubice, Czech Republic; 3 CEITEC Masaryk University, Brno, Czech Republic
HYP4-P06-Mo - Improving robustness and efficiency in bioanalysis using “Trap & Back Elute” two dimensional LC-MS/MSM. WrightLGC, Drug Development Services, Fordham, United Kingdom
HYP 5 electrodriven separations – MSHYP5-P01-Tu - CESI–MS detection and quantitation of neuropeptidesS. LockSciex, Application Development, PUDSEY, United Kingdom
HYP5-P02-Tu - Capillary electrophoresis of selenium species with substrate-assisted laser desorption ICP MS detectionJ. Bělehrad1, A. Pruška1, I. Benešová1, V. Kanický1,2, J. Preisler1,2
1 Masaryk University, Department of Chemistry, Brno, Czech Republic; 2 CEITEC - Central European Institute of Technology, Brno, Czech Republic
HYP5-P03-Tu - Capillary electrophoresis-mass spectrometry as a novel technique in analysis of cholesterol and its metabolitesM. Gregus1, J. Krenkova2, H. Røberg-Larsen3, E. Lundanes3, S.R. Wilson3, F. Foret2, P. Kuban2
1 Masaryk University, Department of Chemistry, Brno, Czech Republic; 2 Institute of Analytical Chemistry of the CAS v. v. i., Brno, Czech Republic; 3 University of Oslo, Department of Chemistry, Oslo, Norway
HYP5-P04-Tu - Improving identification and quantification of polar herbicides by CE-MSS. Lock1, B. Fonslow2, J. Thorn3, W. Hall41 Sciex, Application Development, Pudsey, United Kingdom; 2 Sciex, Marketing, Brea, USA; 3 Sciex, Marketing, Warrington, United Kingdom; 4 Safe Food Alliance, Analytical / Environmental Chemistry, Fresno, USA
HYP5-P05-Tu - Comparison of suitability of two highly sensitive CE-MS interfaces for determination of stability constants of potassium crown ether complexes by affinity CE with MS detectionR. Konášová, D. Koval, V. KašičkaInstitute of Organic Chemistry and Biochemistry of the CAS, Electromigration methods, Prague, Czech Republic
HYP5-P06-Tu - The study of intact casein as a model system for the separation of intact phosphorylated proteins by Capillary Electrospray Ionization (CESI)J. Thorn1, S. Lock1, L. Christopher2
1 ciex, Separations, Warrington, United Kingdom; 2 ciex, Separations, Darmstadt, Germany
HYP5-P07-Tu - Comparison of three CE-ESI-MS interfaces applied to organic acids in negative mode and to digested and reduced proteins in positive modeC. Neusüß, O. Höcker, M. CristinaAalen University, Chemistry, Aalen, Germany
HYP 6 Nanofluidic and microfluidic separations – MSHYP6-P01-Tu - Effect of acidic additives on peak capacity and detectivity in peptide mapping using nano-flow LC/MS with low-density C18 monolithic silica capillary columnsH. Kobayashi, M. Sukegawa, H. WadaShinwa Chemical Industries Ltd., R&D group, Kyoto, Japan
94 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP6-P02-Tu - On-chip coupling of HPLC and droplet microfluidics for further downstream processesA. Peretzki, R. Gerhardt, D. BelderUniversity of Leipzig, Institute of analytical chemistry, Leipzig, Germany
HYP6-P03-Tu - The use of micro-API source in HPLC analysis of lipidsV. Vrkoslav1, T. Strmeň1,2, B. Rumlová1,2, P. Nekvasilová1,2, M. Šulc3, M. Haapala4, R. Kostiainen4, J. Cvačka1,2
1 Institute of Organic Chemistry and Biochemistry of the CAS, Mass Spectrometry, Prague, Czech Republic; 2 Faculty of Science - Charles University in Prague, Department of Analytical Chemistry, Prague, Czech Republic; 3 Czech University of Life Sciences - Faculty of Agrobiology Natural and Food Resources, Department of Chemistry, Prague, Czech Republic; 4 Faculty of Pharmacy - University of Helsinki, Division of Pharmaceutical Chemistry and Technology, Helsinki, Finland
HYP6-P04-Tu - The ultimate limitations in micro-liquid chromatography in terms of speed, efficiency and sensitivityT. Hetzel1, C. Blaesing1, M. Jaeger2, T. Teutenberg1, T.C. Schmidt3
1 Institute of Energy and Environmental Technology, Research analysis, Duisburg, Germany; 2 Niederrhein University of Applied Science, Instrumental Analysis, Krefeld, Germany; 3 University of Duisburg-Essen, Instrumental Analytical Chemistry, Essen, Germany
HYP6-P05-Tu - Microflow LC-MS/MS workflow allows high sensitivity for targeted metabolomicsG. Fischer, B. Ubhi, K. MotamedchabokiSciex, Redwood city, USA
HYP6-P06-Tu - Preparation of phenylboronic acid functionalized hybrid monolithic column for boronate affinity chromatography of diol compounds in a microfluidic systemC. Kip1, G. Nedjip1, C. Demir1, A. Tuncel1,2
1 Hacettepe University, Chemical Engineering Department, Ankara, Turkey; 2 Hacettepe University, Division of Nanotechnology and Nanomedicine, Ankara, Turkey
HYP6-P07-Tu - Evaluation of a microfluidic electrophoresis device coupled to an Orbitrap mass spectrometer for the characterization of biotherapeutics proteinsS. Houel1, E. Redman2, S. Mellors2, A. Bailey1, T. Basarsky2, A. Paulus1, K. Zhou1, J. Josephs1
1 Thermo Fisher Scientific, Life Sciences BU- Chromatography and Mass Spectrometry Division, San Jose, USA; 2 908 Devices- Inc., Research and Development, Boston, USA
HYP 7 LC/MS in lipidomicsHYP7-P01-Tu - HILIC-HPLC/ESI-MS analysis of gangliosides in biological samplesR. Hajek, R. Jirasko, M. Lísa, E. Cífková, M. HolčapekUniversity of Pardubice, Analytical Chemistry, Pardubice, Czech Republic
HYP7-P02-Tu - Quantification of steroid hormones in human serum by liquid chromatography-high resolution tandem mass spectrometryS. Matysik, G. LiebischUniversity Hospital Regensburg, Regensburg, Germany
HYP7-P03-Tu - Profiling of constitutional isomeric phospholipids by hydrophilic interaction LC-ESI-MS/MSC. Vosse, H. HayenUniversity of Muenster, Institute of Inorganic and Analytical Chemistry, Muenster, Germany
HYP7-P04-Tu - Challenges in the analysis of wheat flour phospholipids in dough by LCMSL. Lauridsen, B. Høj HornshøjDuPont Nutrition Biosciences ApS, Advanced Analysis, Brabrand, Denmark
HYP7-P05-Tu - Development of a sensitive nano LC-MS approach for the in-vivo analysis of antibodies on peptide levelA. Doell1,2, M. Hollmann1, O. Schmitz2
1 AbbVie Germany, Drug Product Development, Ludwigshafen am Rhein, Germany; 2 University of Duisburg-Essen, Faculty of Chemistry- Applied Analytical Chemistry, Essen, Germany
HYP7-P06-Tu - LC-MS analysis of endogenous lipid mediators with anti-diabetic propertiesK. Syslová, M. MikoškaUniversity of Chemistry and Technology, Department of Organic Technology, Prague 6, Czech Republic
95HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP 8 Supercritical fluid chromatography – MSHYP8-P01-Tu - Supercritical fluid chromatography on chiral separation of enantiomeric drugs in human plasma with MS/MS detectionY. Watabe, T. Hattori, T. Iida, Y. Fujito, S. Kawano, Y. HayakawaShimadzu Corporation, Global Applicatio Development Center, Kyorto, Japan
HYP8-P02-Tu - Analysis of amino acids by direct coupling of supercritical fluid chromatography with tandem mass spectrometryD. Wolrab, P. Frühauf, L. Niederstaetter, C. GernerUniversity of Vienna, Department of Analytical Chemistry, Vienna, Austria
HYP8-P03-Tu - Development and comparison of quantitative methods using orthogonal chromatographic techniques for the analysis of potential mutagenic impuritiesJ. Simeone, P. HongWaters Corporation, Separation Technologies, Milford, USA
HYP8-P04-Tu - Hyphenated techniques in lipidomics: comparison of UPLC vs UPC2 separations coupled to QTOF technologyM. Maheux, C.P. LafranceTransBIOTech, Analytical Chemistry & Biochemistry, Lévis, Canada
HYP8-P06-Tu - Online SFE-SFC-MS for direct extraction and analysis of designer drugs in urine samplesK.A. Schug1, P. Wicker1, V. Pauk2, A. Berghorn1, C. Qiu1, V. Havlicek2, K. Lemr2
1 The University of Texas at Arlington, Chemistry and Biochemistry, Arlington, USA; 2 Palacky University, Analytical Chemistry, Olomouc, Czech Republic
HYP 9 Biomarker discovery in metabolomicsHYP9-P01-We - Solid phase microextraction for brain tumor metabolite analysisP.Z. Goryńska1, K. Goryński1, K. Chmara1, K. Jaroch1, D. Paczkowski2, M. Harat2, B. Bojko1
1 Faculty of Pharmacy- Collegium Medicum Nicolaus Copernicus University in Bydgoszcz, Pharmacodynamics and Molecular Pharmacology, Bydgoszcz, Poland; 2 10th Military Research Hospital and Polyclinic Independent Public Healthcare Center in Bydgoszcz, Neurosurgery Clinic, Bydgoszcz, Poland
HYP9-P02-We - Analysis of eicosanoids in biological samples using the coupling of separation techniques and mass spectrometryM. Chocholoušková, E. Cífková, M. HolčapekUniversity Pardubice, Faculty of Chemical Technology, Pardubice, Czech Republic
HYP9-P04-We - LC-MS analysis columns for intact amino acids and neurotransmitters without derivatizationI. Yazawa, H. TachikawaImtakt Corporation, Technical Center, Kyoto, Japan
HYP9-P05-We - Distribution of exogenous and endogenous CYP3A markers and related factors in healthy males and femalesA.H. Kim, J. Lee, S. Yi, S. Lee, S.H. Yoon, K.S. Yu, I.J. Jang, J.Y. ChoSeoul National University College of Medicine and Hospital, Clinical Pharmacology and Therapeutics, Seoul, Republic of Korea
HYP 10 MS based OMICSHYP10-P01-We - Direct analysis and discrimination of thiophenic and sulfidic compounds in crude oilsY. Han, Y. Zhang, Z. FanState Key Laboratory of Heavy Oil Processing, College of Chemical Engineering- China University of Petroleum, Beijing, China
HYP10-P03-We - Evaluation of a novel atmospheric pressure ionization source (UniSprayTM) for natural compounds analysisO. Ciclet1, D. Barron2, J.L. Veuthey1, D. Guillarme1, A. Grand-Guillaume-Perrenoud2
1 School of pharmaceutical Sciences- University of Geneva, Analytical sciences, Genève 4, Switzerland; 2 Nestlé Institute of Health Sciences, Natural Bioactives and Screening, Lausanne, Switzerland
96 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP10-P04-We - Direct analysis in real time combined with modified quick polar pesticides extraction method to determine highly polar pesticides in lettuce and celeryF.J. Lara1, D. Chan2, M. Dickinson2, A.S. Lloyd2, S.J. Adams2, A.M. García-Campaña1
1 University of Granada, Analytical Chemistry, Granada, Spain; 2 Fera Science Ltd., York, United Kingdom
HYP10-P05-We - Metabolomics-driven integrative network analysis of chemical-induced biotic stimulation in photosynthetic microalga, Chlamydomonas reinhardtiiJ.E. Lee, D.Y. LeeKookmin University, Bio and Fermentation Convergence Technology, Seoul, Republic of Korea
HYP 11 Maldi in LC coupling and MS imagingHYP11-P01-We - Identification of possible biomarkers for breast tumor mice from phospholipids profiling determined by using MALDI Imaging and UPLC/MSG. Bang1, S. Kim2, Y.H. Kim1
1 Korea Basic Science Institute, Biomedical Omics Group, Cheongju, Republic of Korea; 2 Kyungpook National University, Department of Chemistry, Daegu, Republic of Korea
HYP11-P02-We - Comparison of MALDI-MSI and LC-MS for pharmacokinetic study of metforminŠ. Strnad1, D. Sýkora2, J. Cvačka1, L. Maletínská3, Z. Pirník4, Z. Majerčíková3, J. Kuneš3,5, V. Vrkoslav1
1 Institute of Organic Chemistry and Biochemistry AS CR, Mass spectrometry, Prague 6, Czech Republic; 2 University of Chemistry and Technology, Analytical chemistry, Prague 6, Czech Republic; 3 Institute of Organic Chemistry and Biochemistry AS CR, Biochemistry and Molecular Biology, Prague 6, Czech Republic; 4 University of Veterinary Medicine and Pharmacy, Pharmacology and toxicology, Košice, Slovakia; 5 Institute of Physiology AS CR, Experimental Hypertension, Prague 4, Czech Republic
HYP11-P03-We - β-secretase enzyme assay by MALDI TOF MSM. Machálková1, J. Schejbal2, Z. Glatz2, J. Preisler1
1 Masaryk University- Faculty of Science, Department of Chemistry, Brno, Czech Republic; 2 Masaryk University- Faculty of Science, Department of Biochemistry, Brno, Czech Republic
HYP 12 Quantitation in LC/MSHYP12-P01-We - Sensitive UPLC method with tandem mass detection for analysis of genotoxic impurities of imatinib mesylate drugM. Maziarz, M. WronaWaters Corporation, Scientific Operations, Milford, USA
HYP12-P02-We - Qualitative and quantitative analysis of polyglycerol esters mixtures used in cosmetic formulationsS. Cassel1, J.C. Garrigues1, M. Blanzat1, N. Ritter2, J.D. Rodier2
1 Université Paul Sabatier Toulouse III, Chemistry- IMRCP- UMR 5623, Toulouse, France; 2 Gattefossé, SAINT-PRIEST Cedex, France
HYP12-P04-We - Simultaneous,fast and simple quantification of oxidative damage biomarker and cotinine in human urine by on-line SPE LC-MS/MS: Correlation with tobacco exposure biomarkers NNALH.L. Lee1, C.Y. Chen1, Y.W. Lin2
1 Fu Jen Catholic University, Chemistry, New Taipei City, Taiwan- Province of China; 2 Fu Jen Catholic University, Public Health, New Taipei City, Taiwan- Province of China
HYP12-P05-We - Trace level analysis of eleven genotoxic impurities in a penultimate pharmaceutical intermediate using the emerging lc-ms technology, the Acquity® QDa® Mass DetectorP. Yogendrarajah, W. Peys, E. Verhoeven, M. HellingsJanssen Pharmaceuticals of Johnson & Johnson, Analytical Development- Pharmaceutical Development and Manufacturing Sciences, Beerse, Belgium
97HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP12-P06-We - Development and validation of HPLC-APCI-MS/MS method for quantitative determination of tocotrienols in human breast adipose tissueE. Bartosińska1, J. Jacyna1, A. Borsuk1, M. Kaliszan2, W.J. Kruszewski3,4, Z. Jankowski2, D. Siluk1
1 Department of Biopharmaceutics and Pharmacodynamics- Medical University of Gdańsk, Gdańsk, Poland; 2 Department of Forensic Medicine- Medical University of Gdańsk, Gdańsk, Poland; 3 Division of Propedeutics of Oncology- Medical University of Gdańsk, Gdynia, Poland; 4 Department of Oncological Surgery- Gdynia Centre of Oncology- Maritime Hospital in Gdynia, Gdynia, Poland
HYP12-P07-We - Transferring and improving a legacy HPLC-UV cleaning validation method by employing UHPLC and mass detectionC. Henry1, H. Boiteux2, M. Wrona3, J. Kirk4
1 Waters Corporation, Scientific Operations, Cheshire, United Kingdom; 2 Waters Corporation, Separations Business Development Manager, Cedex, France; 3 Waters Corporation, Scientific Operations, Milford, USA; 4 Waters Corporation, Scientific Operations, Wilmslow, United Kingdom
HYP12-P08-We - Detection and quantification of fumonisins and hydrolysed fumonisins in biological matrices with LC-MS/MSG. Bichl1, T. Czabany1, H.E. Schwartz-Zimmermann2, D. Schatzmayr1, I. Dohnal11 BIOMIN Research Center, Tulln, Austria; 2 Christian Doppler Laboratory for Mycotoxin Metabolism and Center for Analytical Chemistry, Department for Agrobiotechnology IFA-Tulln of the University of Natural Resources and Life Sciences Vienna, Tulln, Austria
HYP12-P09-We - Development and optimization of UHPLC-MS/MS method for analysis of selected antiviral compoundsJ. Pavlík1, O. Martinec2, L. Nováková1, L. Červený2
1 Charles University- Faculty of Pharmacy, Department of Analytical Chemistry, Hradec Králové, Czech Republic; 2 Charles University- Faculty of Pharmacy, Department of Pharmacology and Toxicology, Hradec Králové, Czech Republic
HYP12-P10-We - HPLC-ESI-QTOF-MS/MS based quantitative amino acid analysis and simultaneous metabolic profiling of stressed human corneal epithelial cells with data-independent SWATH acquisitionC. Sanwald1, S.K. Wiedmer2, M. Lämmerhofer1
1 University of Tuebingen, Institute of Pharmaceutical Sciences- Pharmaceutical Bio-Analysis, Tuebingen, Germany; 2 University of Helsinki, Department of Chemistry, Helsinki, Finland
HYP12-P11-We - Experimental design approach used for optimisation of forced degradation study of atorvastatin by LC/MS characterisation of the degradation productsM. Hadzieva Gigovska1, A. Petkovska1, I. Brasnarska1, J. Acevska2, S. Ugarkovic1, A. Dimitrovska2
1 Alkaloid AD Skopje, Research & development, Skopje, Macedonia; 2 Faculty of Pharmacy- University “Ss Cyril and Methodius”, Skopje, Macedonia
HYP12-P12-We - Easy and robust method for identification and quantification of nucleotide pool in bacterial cellsE. Zbornikova1,2, D. Rejman1, L. Krasny3, V. Vavrik4
1 Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Prague 6, Czech Republic; 2 Charles University, Department of Analytical Chemistry, Prague 2, Czech Republic; 3 Czech Academy of Sciences, Institute of Microbiology, Prague 4, Czech Republic; 4 Umeå University, Umea, Sweden
HYP12-P13-We - Fully automated derivatization -quantification of glyphosate and AMPA in beer using a standard UHPLC-MS/MS systemA. Grüning, J. Sander, R. Ludwig, P. JochemsShimadzu Europa GmbH, CIPS, Duisburg, Germany
HYP12-P14-We - Identification of prohibited skin lightening agents in cosmetic products using UHPLC with PDA and mass detectionM. Twohig1, P. Hong2, H. Boiteux3
1 Waters Corporation, Scientific Operations, Milford, USA; 2 Waters Corporation, Separations Marketing, Milford, USA; 3 Waters S.A.S, Separations Business Development, Saint-Quentin, France
98 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP12-P15-We - Development of HILIC–ESI/MS–MS method for the quantification of olopatadine in human tearsJ. Maksic1, A. Stajić2, M. Knežević3, B. Dačić3, B. Jančić-Stojanović2, M. Medenica4
1 Medical Military Academy, Department of drug control and examination, Belgrade, Serbia; 2 University of Belgrade-Faculty of Pharmacy-, Department of Drug Analysis, Belgrade, Serbia; 3 Clinical Center of Serbia, University Eye Clinic, Belgrade, Serbia;
4 University of Belgrade-Faculty of Pharmacy, Department of Physical Chemistry and Instrumental Methods, Belgrade, Serbia
HYP12-P16-We - Validation of an analytical method for the quantification of fatty acid amides in cerebrospinal fluid matrix by LC-MS/MSC. Fernandes-Lopes1, A. I. Loureiro1, P. Moser1, P. Soares-da-Silva1,2
1 Bial - Portela & Cª- S.A., Department of Research and Development, Coronado S. Romão e S. Mamede, Portugal; 2 Faculty of Medicine, Department of Pharmacology and Therapeutic, Porto, Portugal
HYP12-P17-We - Evaluation of compact mass detector: A new dimension for chromatographyP. Karmuse1, A. Singh1, S. Sanikommu1, A. Clarke2
1 Novartis Healthcare Pvt. Ltd., Analytical Research and Development, Hyderabad, India; 2 Novartis Pharma AG, Chemical and Analytical Development, Basel, Switzerland
HYP12-P18-We - LC-MS/MS analysis of peptides in brain with fluorous derivatizationE. Kiyokawa, T. Hayama, R. Koga, H. Yoshida, M. Yamaguchi, H. NohtaFukuoka University, Faculty of Pharmaceutical Sciences, Fukuoka, Japan
HYP12-P19-We - The step by step guide to developing a robust assay for a new compound in bioanalysis using LC-MS/MSN. CordenLGC, Bioanalysis, Fordham, United Kingdom
HYP12-P20-We - Higenamine determination in nutritional supplements by UPLC/MS/MS methodA. Stajić1, M. Anđelković2, N. Dikić2, J. Rašić3, D. Ivanović1, B. Jančić-Stojanović1
1 Faculty of Pharmacy- University of Belgrade, Department of Drug Analysis, Belgrade, Serbia; 2 Antidoping Agency of Serbia, Antidoping Agency of Serbia, Belgrade, Serbia; 3 Beo-lab, Belgrade, Serbia
HYP12-P21-We - A faster and sensitive LC-MS/MS method for pharmacokinetic assessment of anti-epileptic drugsS. Joseph1, S. Salman Lateef1, P. Kole2, P. Hörth3
1 Agilent Technologies, Segment Marketing Market Development, Bangalore, India; 2 Biocon Bristol-Myers Squibb Research & Development Center, Pharmaceutical Candidate Optimization, Bangalore, India; 3 Agilent Technologies, Waldbronn, Germany
HYP12-P22-We - Mass spectrometry for every chromatographer – A new single quadrupole mass spectrometer to overcome common detection challengesS. Meding, K. Lovejoy, M. RuehlThermo Fisher Scientific, Chromatography & Mass Spectrometry, Germering, Germany
HYP12-P23-We - LC-MS determination of non-ionic surfactant residues on pharmaceutical manufacturing equipment surfaces after cleaning procedureR. Klinkenberg1, D. Monseur1, B. Mertens1, A. Brouwers1, J. Harzimont1, J.C. Van Heugen1, L. Belhassan2, B. Streel11 Galephar M/F, Quality Control, Marche-en-Famenne, Belgium; 2 Laboratoires SMB, Research & Development, Brussels, Belgium
HYP12-P24-We - Improved sensitivity for LC-MS quantitation of biologics in plasma using trap-and-elute microflow LC-MSE. Lin, K. Motamedchaboki, R. van SoestSciex, Separations, Redwood City, USA
HYP12-P25-We - High throughput microflow LC-MS/MS for high sensitivity peptide quantitation in targeted assaysE. Lin1, R. van Soest1, C. Hunter2, M. Razavi31 Sciex, Separations, Redwood City, USA; 2 Sciex, Technical Marketing, Redwood City, USA; 3 SISCAPA Assay Technologies, Lab Operations, Victoria, Canada
99HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
HYP 13 MS applications from inorganics to pharmaceuticalsHYP13-P01-Tu - Investigation of an extraction and separation method for the analysis of mercury species in sedimentsC. Kowalczyk, O. SchmitzUniversity Duisburg-Essen, Essen, Germany
HYP13-P02-Tu - Quantitative analysis of arsenic species in rice using LC-ICP-MSU. Oppermann1, J. Knoop2, J. Schram3
1 Shimadzu Europa GmbH, Marketing Analytical BU, Duisburg, Germany; 2 Shimadzu Europa GmbH, CIPs, Duisburg, Germany;
3 University of Applied Sciences, FB Chemie, Krefeld, Germany
HYP 14 High-throughput, data processing and bioinformaticsHYP14-P01-Tu - Broad screening of 100 regulated ingredients in cosmetics using UHPLC-Q-Orbitrap mass spectrometry combined with accurate mass database and spectral library search strategyX. Meng, Q. Ma, H. BaiChinese Academy of Inspection and Quarantine, Institute of Industrial and Consumer Product Safety, Beijing, China
HYP14-P02-Tu - High-throughput data processing of accurate mass LC-MS data for the characterization of low molecular weight polymersM. Dunkle1, M. van Engelen1, G. Groeneveld2, E. Mes1, P. Schoenmakers2
1 Dow Benelux, Analytical Sciences, Hoek, The Netherlands; 2 University of Amsterdam, Van 't Hoff Institute for Molecular Sciences, Amsterdam, The Netherlands
HYP14-P03-Tu - Modular implementation of hadamard encoding in LC and facile transfer to various separation and detection modesA. Siegle, O. TrappLudwig-Maximilians-University Munich, Faculty for Chemistry and Pharmacy, München, Germany
HYP14-P04-Tu - LC-MS/MS based searchable short peptide spectrum library platformW. Kim, J.S. LeeGyeonggido Business&Science Accelerator, Biocenter- Analysis Support Team, Gyeonggi-do, Republic of Korea
Program track Applications (APP)APP 1 Forensics, doping and toxicologyAPP1-P01-Mo - Chemical profiling of cannabis seizures by GC/MS: Determination of the inter- and intra-seizure variabilityA. Slosse1, F. Van Durme2, N. Samyn2, Y. Vander Heyden1
1 Vrije Universiteit Brussel VUB, Departement of Analytical Chemistry and Pharmaceutical Technology FABI, Brussels, Belgium;
2 National Institute for Criminalistics and Criminology, Department Drugs And Toxicology, Brussels, Belgium
APP1-P02-Mo - UPLC-QqQ-MS analysis of gamma-HB and its isomers, alpha-HB and beta-HB, in serum: Novel perspectives in the forensic GHB determinationR. Gottardo, R. Lockwood, V. Paterlini, F. Tagliaro, F. BortolottiUniversity of Verona, Dept. of Diagnostics and Public Health, Verona, Italy
APP1-P03-Mo - Using UHPLC-HR-MS to investigate the equine metabolites of the selective androgen receptor modulator LGD-4033 for doping control purposesA. Hansson1, H. Knych2, S. Stanley2, M. Thevis3, U. Bondesson4, M. Hedeland4
1 Uppsala University, Medicinal Chemistry, Uppsala, Sweden; 2 School of Veterinary Medicine- University of California, K. L. Maddy Equine Analytical Chemistry Laboratory, Davis, USA; 3 German Sport University, Institute of Biochemistry and Center for Preventive Doping Research, Cologne, Germany; 4 National Veterinary Institute SVA, Department of Chemistry- Environment and Feed Hygiene, Uppsala, Sweden
APP1-P04-Mo - Development and validation of an liquid chromatography tandem-mass spectrometry method for the simultaneous determination of hair growth compounds in dietary supplementsJ.H. Lee, H.N. Park, G.H. Kang, N.S. Kim, J.H. Kim, T.I. Hwang, S.S. Park, S.K. Park, S.Y. BaekMinistry of Food and Drug Safety, Advanced Analysis Team, Cheongju-si, Republic of Korea
100 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP1-P05-Mo - Handheld portable device based on differential mobility spectrometry for forensic applicationsM. Pavlačka1, R. Mázl2, M. Zástěra2, K. Kortánková2, J. Bláha2, K. Ventura1, P. Bajerová1
1 University of Pardubice, Analytical chemistry, Pardubice, Czech Republic; 2 RS Dynamics s.r.o., Prague, Czech Republic
APP1-P06-Mo - HPLC determination of transferrin glycoforms with fluorescent terbium adducts: the tool to detect CDT in post-mortem bloodD. Sorio, F. Bortolotti, E.F. De Palo, A. Bertaso, F. TagliaroUniversity of Verona, Dept. of Diagnostics and Public Health, Verona, Italy
APP1-P07-Mo - A UHPLC-MS/MS method for the detection of drugs and pharmaceuticals in human bonesA. Orfanidis1, O. Mastrogianni2, H. Gika1, G. Theodoridis3, E. Zaggelidou2, N. Raikos1
1 Laboratory of Forensic Medicine & Toxicology- Medical School, Aristotle University, Thessaloniki, Greece; 2 Laboratory of Forensic Service, Ministry of Justice of Thessaloniki, Thessaloniki, Greece; 3 Laboratory of Analytical Chemistry- School of Chemistry, School of Chemistry, Thessaloniki, Greece
APP1-P08-Mo - Differentiation and identification of explosives formulations by means of HPLC-MST. Schachel, U. KarstWestfälische Wilhelms-Universität Münster, Institute of Inorganic and Analytical Chemistry, Münster, Germany
APP1-P09-Mo - Introduction of a screening method for 273 drugs of abuse, new psychoactive substances and their metabolites in biological matrices on UHPLC-MS/MSA. Dobos, K. Kemenes, J. Csáky, Á. Kerner, B. Tajti, H. Schmehl-Révész, G.P. SomogyiHungarian Institute for Forensic Sciences, Department of Forensic Toxicology, Budapest, Hungary
APP1-P10-Mo - Development and validation of a novel method for the analysis of bisphenol biomarkers in human by on-line SPE/LC/MS/MSM. Lacroix1, F. Grandin1, A. Berrebi2, C. Viguie1, V. Gayrard1, N. Picard-hagen1, L. Debrauwer3
1 INRA/ENVT, UMR 1331 TOXALIM, Toulouse, France; 2 CHU Paule de Viguier, Services de Gynécologie-Obstétrique, Toulouse, France; 3 INRA/Metatoul, UMR 1331 Toxalim, Toulouse, France
APP1-P11-Mo - Microextraction by packed sorbent for post mortem whole blood sample preparation in forensic analyses of benzodiazepinesL. Rezende Togni1,2, J.L. da Costa3, M. Franco Maggi Tavares2,4
1 Albert Einstein Hospital, Clinical Laboratory, Sao Paulo, Brazil; 2 University of Sao Paulo, Faculty of Pharmaceutical Sciences, Sao Paulo, Brazil; 3 University of Campinas, Faculty of Pharmaceutical Sciences, Campinas, Brazil; 4 University of Sao Paulo, Institute of Chemistry, Sao Paulo, Brazil
APP1-P12-Mo - Optimization of nitrate ester explosives with UHPLC-ESI-MS by using design of experimentsD.B.A. Malheiro, A.K. Ohlsson, J.P.B. HaraldstedUniversity of Copenhagen, Department of Plant and Environmental Sciences, Frederiksberg C, Denmark
APP1-P13-Mo - The forensic study of the possible tetrahydrocannabinol (THC) intake from cosmetic products containing Cannabis sativaK. Hajkova1,2, A. Nemeskalova1,2, S. Bicanova1,2, D. Sykora2, J. Rak1, M. Kuchar1
1 UCT Prague, Forensic Laboratory of Biologically Active Substances, Prague, Czech Republic; 2 UCT Prague, Department of Analytical Chemistry, Prague, Czech Republic
APP1-P14-Mo - Surface influence on desorption nanoelectrospray ionizationK. Lemr1, L. Borovcová1, P. Barták1, L. Hartmanová1, T. Matušů1, I. Lorencová1, V. Havlíček2
1 Palacky University, Department of Analytical Chemistry- Regional Centre of Advanced Technologies and Materials, Olomouc, Czech Republic; 2 Institute of Microbiology v.v.i.-The Czech Academy of Sciences, Laboratory of Molecular Structure Characterization, Prague, Czech Republic
101HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP 2 ProteomicsAPP2-P02-Mo - Development of an all-recombinant intact protein standard for LC MS application development and system suitability testingR. van Ling1, R. Viner2, K. Opperman3, H. Cardasis2, V. Vitkovske4, S. Bechler5, S. Lin5, L. Taujenis4, V. Gohil4, J. Rogers3, E. Capkauske4, K. Bargaila4
1 Thermo Fisher Scientific, European Support, Breda, The Netherlands; 2 Thermo Fisher Scientific, Research & Development, San Jose, CA, USA; 3 Thermo Fisher Scientific, Research & Development, Rockford, IL, USA; 4 Thermo Fisher Scientific, Research & Development, Vilnius, Lithuania; 5 Thermo Fisher Scientific, Research & Development, Sunnyvale, CA, USA
APP2-P03-Mo - Proteomic and pigment analysis of Siamese crocodile (Crocodylus siamensis) eggshellI. Mikšík1, S. Pataridis1, A. Eckhardt1, D. Sedmera2
1 Institute of Physiology CAS, Analysis of Biologically Important Compounds, Praha 4, Czech Republic; 2 First Faculty of Medicine, Charles University, Institute of Anatomy, Praha 2, Czech Republic
APP2-P04-Mo - High pH RP-HPLC as an orthogonal fractionation method in LC-MS/MS analysis of human follicular fluid protein and peptide compositionA. Lewandowska1, K. Macur1, M. Thiel1, P. Czaplewska1, J. Liss2, K. Łukaszuk2,3, S. Ołdziej11 University of Gdańsk, Intercollegiate Faculty of Biotechnology UG&MUG, Gdańsk, Poland; 2 INVICTA, Fertility and Reproductive Centre, Gdańsk, Poland; 3 Medical University of Gdańsk, Department of Obstetrics and Gynecological Nursing, Gdańsk, Poland
APP2-P05-Mo - Interaction between peptides and pyrophosphate molecules investigated by the use of HPLC, MS and LC/MS techniquesM. Thiel, A. Lewandowska, S. OłdziejUniversity of Gdańsk, Intercollegiate Faculty of Biotechnology of UG i MUG, Gdańsk, Poland
APP2-P06-Mo - Single-cell analysis of caspase-3/7 activation in developing murine cellsV. Ledvina, K. KlepárníkInstitue of Analytical Chemistry of the CAS v. v. i., Department of Bioanalytical Instrumentation, Brno, Czech Republic
APP2-P07-Mo - High performance monolithic silica columns for capillary HPLCK. Kanno1, M. Motokawa1, A. Sato1, K. Morisato1, Y. Konno1, M. Jiao1, N. Gribov2, G. Alkema2, H. Minakuchi3, A. Sato1
1 GL Sciences Inc., Research and development, Iruma, Japan; 2 GL Sciences B.V., Research and development, Eindhoven, The Netherlands; 3 Kyoto Monotech Co.- Ltd, Research and development, Kyoto, Japan
APP2-P08-Mo - Association between adipophilin levels and lipid content in human breast milk investigated using ultra-high performance liquid chromatography and mass spectrometryT. Pavlová1,2, V. Vidova1, E. Cechova1, Z. Hodicka3, J. Bienertova-Vasku1,2, Z. Spacil11 Masaryk University- Faculty of Science, Research Centre for Toxic Compounds in the Environment, Brno, Czech Republic;
2 Masaryk University- Faculty of Medicine, Department of Pathological Physiology, Brno, Czech Republic; 3 University Hospital Brno, Department of Obstetrics and Gynaecology, Brno, Czech Republic
APP2-P09-Mo - Considerations for selecting the optimal stationary phases for proteomic trap-elute nanochromatographyM.C. JungWaters Corporation, CG R&D, Milford, USA
APP2-P10-Mo - Phosphoproteomic study of radiosensitization mechanisms of autophagy inhibitor Lys05 on non-small cell lung cancer cellsM. Ondrej1, L. Cechakova1, I. Fabrik2, B. Salovska3, A. Tichy1
1 University of Defence in Brno- Faculty of Military Health Sciences, Department of Radiobiology, Hradec Králové, Czech Republic; 2 University of Defence in Brno- Faculty of Military Health Sciences, Department of Molecular Pathology and Biology, Hradec Králové, Czech Republic; 3 Institute of Molecular Genetics of the ASCR, Laboratory of Genome Integrity, Prague, Czech Republic
APP2-P11-Mo - An improved detection of multiphosphorylated peptides using novel magnetic TiO2 based nanomaterialR. Kupcik1, P. Rehulka2, J.M. Macak3, I. Fabrik2, J. Klimentova2, H. Rehulkova2, P. Krulisova1, J. Stulik2, Z. Bilkova1
1 University of Pardubice- Faculty of Chemical Technology, Department of Biological and Biochemical Sciences, Pardubice, Czech Republic; 2 University of Defence- Faculty of Military Health Sciences, Department of Molecular Pathology and Biology, Hradec Kralove, Czech Republic; 3 University of Pardubice- Faculty of Chemical Technology, Center of Materials and Nanotechnologies, Pardubice, Czech Republic
102 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP2-P12-Mo - Robust and sensitive workflow for qualitative and quantitative analysis of intact monoclonal antibodies using a MicroLC and TripleTOF Mass SpectrometryG. Fischer, K. Motamedchaboki, R. Van Soest, D. Warren, J. Albanese, E. LinSciex, Redwood City, USA
APP2-P13-Mo - Characterization of a poly(dimethylsiloxane) microfluidic chip containing adsorbed trypsin for rapid protein digestionA. Kecskemeti, C.N. Nagy, A. GasparUniversity of Debrecen, Department of Inorganic and Analytical Chemistry, Debrecen, Hungary
APP2-P14-Mo - Deep and reproducible human proteome profiling with novel nano flow LC technology and HRAM mass-spectrometryR. Bauder1, A. Boychenko2, M. Baynham3, R. Swart2, M. Ruehl21 Thermo Fisher Scientific, Product Marketing, Chelmsford, USA; 2 Thermo Fisher Scientific, Chromatography and Mass Spectrometry Division, Germering, Germany; 3 Thermo Fisher Scientific, Chromatography and Mass Spectrometry Division, Runcorn- Cheshire, United Kingdom
APP2-P15-Mo - Improved sensitivity and robustness with capillary flow LC-MS targeted protein quantificationA. Boychenko, S. Meding, M. Ruehl, R. SwartThermo Fisher Scientific, Chromatography & Mass Spectrometry, Germering, Germany
APP 3 Sample preparation and automationAPP3-P01-Mo - The efficiency of different microextraction approaches in the quantification of bioactive metabolites in food. The case study of coffeeJ.A.M. Pereira1, P. Porto-Figueira1, A. Chmiel1,2, M. Kotowicz1,2, W. Mamala1,2, J. Pataca1, J.A.O. Figueira1, J.S. Câmara1,3
1 CQM - Centro de Química da Madeira- Universidade da Madeira, ACE lab - Analytical Chemistry and Enology lab, Funchal, Portugal; 2 University of Wroclaw- Biotechnology- plac Uniwersytecki 1- 50-137 Wrocław- Poland, Biotechnology, Wrocław, Poland; 3 Faculdade de Ciências Exatas e da Engenharia- Universidade da Madeira, Funchal, Portugal
APP3-P02-Mo - Deep eutectic solvents as multipurpose media for bioactive natural productsK.M. Jeong, D.E. Yoo, S.Y. Han, Y. Jin, J. LeeSungkyunkwan University, Pharmacy, Suwon, Republic of Korea
APP3-P03-Mo - Development of a high throughput SPME-HPLC-MS/MS in-vitro assay for monitoring time course changes in kinetics and dynamics of cell line systemsE. Boyaci, B. Bojko, N. Reyes-Garcés, G.A. Gómez-Ríos, J.J. Poole, J. PawliszynUniversity of Waterloo, Chemistry, Waterloo, Canada
APP3-P04-Mo - Automated LC/MS purification of compound librariesF. Rieck, R. Guilliet, S. UllrichAgilent Technologies, Liquid Phase Separations Division, Waldbronn, Germany
APP3-P05-Mo - Sample preconcentration using vision-controlled droplet evaporation for high-throughput LC-MS-based metabolomicsP. Miggiels1, P. Vulto2, A. Mashaghi1, I. Kohler1, T. Hankemeier1
1 Leiden Academic Centre for Drug Research- Leiden University, Analytical Biosciences, Leiden, The Netherlands; 2 MIMETAS BV, Leiden, The Netherlands
APP3-P06-Mo - UHPLC-PDA determination of five antibiotics in human plasma using air assisted dispersive liquid-liquid microextraction with solidification of the floating organic dropletsV. Ferrone1, M. Carlucci2, R. Cotellese2, L. Di Marco1, G. Carlucci1, F. Epifano1, S. Fiorito1, S. Genovese1, V.A. Taddeo1
1 University "G.d'Annunzio", Pharmacy, Chieti, Italy; 2 University "G.d'Annunzio", Department of Medical- Oral and Biotechnological Sciences, Chieti, Italy
APP3-P07-Mo - Modern trends in sample preparation techniques in clinical researchL. Kujovska Krcmova1,2, L. Javorska1,2, K. Kucerova1,2, S. Klabackova1,2, J. Jenco1,2, P. Solich1
1 Charles University- Faculty of Pharmacy, Department of Analytical Chemistry, Hradec Kralove, Czech Republic; 2 University Hospital, 3rd Internal Gerontometabolic Clinic, Hradec Kralove, Czech Republic
103HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP3-P08-Mo - A new vortex-assisted supramolecular solvent liquid-liquid microextraction followed by high performance liquid chromatography for trace analysis of phenols in water samplesK. Seebunrueng, S. SrijaranaiKhon Kaen University, Materials Chemistry Research Center- Department of Chemistry, Khon Kaen, Thailand
APP3-P09-Mo - Application of miniaturized extraction techniques for analysis of tocopherols in clinical practice - first resultsS. Klabačková1,2, L. Kujovská Krčmová1,2, B. Červinková1,2
1 Charles University- Faculty of Pharmacy, Department of Analytical Chemistry, Hradec Králové, Czech Republic; 2 University Hospital, 3rd Internal Gerontometabolic Clinic, Hradec Králové, Czech Republic
APP3-P10-Mo - Polyamide nanofibers as the sorbents for on-line SPE-HPLC determination of Bisphenol A in river water samplesM. Parmová1, L. Chocholoušová Havlíková1, D. Šatínský1, J. Chvojka2
1 Charles University- Faculty of Pharmacy in Hradec Králové, Department of Analytical Chemistry, Hradec Králové, Czech Republic; 2 Technical University of Liberec, The Institute for Nanomaterials- Advanced Technology and Innovation, Liberec 1, Czech Republic
APP3-P11-Mo - Conventional and modern extraction approaches to the determination of quercetin ant its metabolites in rat plasmaV. Pilařová1, K. Plachká1, L. Chrenková1, O. Novák2, L. Nováková1
1 Faculty of Pharmacy in Hradec Králové- Charles University, Department of Analytical Chemistry, Hradec Králové, Czech Republic; 2 Laboratory of Growth Regulators- Centre of the Region Haná for Biotechnological and Agricultural Research- Institute of Experimental Botany CAS & Faculty of Science of Palacký University, Olomouc, Czech Republic
APP3-P12-Mo - Micro-SPE in pipette tips as the tool for analysis of drugs in serumH. Vlčková1, V. Pilařová1, O. Novák2, P. Solich1, L. Nováková1
1 Charles University- Faculty of Pharmacy in Hradec Králové, Department of analytical chemistry, Hradec Králové, Czech Republic; 2 Laboratory of Growth Regulators- Centre of the Region Haná for Biotechnological and Agricultural Research- Institute of Experimental Botany CAS & Faculty of Science of Palacký University, Olomouc, Czech Republic
APP3-P13-Mo - Simulteaneous determination of 19 synthetic water-soluble dyes in products intended for children by matrix solid-phase dispersion and liquid chromatography-tandem mass spectrometryE. Guerra, M. Llompart, C. Garcia-JaresUniversity of Santiago de Compostela, Analytical Chemistry- Nutrition and Food Science, Santiago de Compostela, Spain
APP3-P14-Mo - Determination of lovastatin using UHPLC-MS/MS method and automated SPE procedure with laboratory-made molecularly imprinted polymer sorbentK. Plachká, L. Zelená, P. Svoboda, H. Sklenářová, L. NovákováCharles University- Faculty of Pharmacy, Department of Analytical Chemistry, Hradec Králové, Czech Republic
APP3-P15-Mo - GPC cleanup of olive oil samplesM. Schulze, K. MonksKNAUER Wissenschaftliche Geräte GmbH, Applications & Academy, Berlin, Germany
APP3-P16-Mo - On-line molecularly imprinted solid phase extraction coupled to chromatographic separation for determination of mycoxotin zearalenone in beer samplesI. Lhotská, M. Parmová, B. Gajdošová, D. ŠatínskýFaculty of Pharmacy in Hradec Králové- Charles University, Department of Analytical Chemistry, Hradec Králové, Czech Republic
APP3-P17-Mo - Magnetic solid-phase extraction based amino-modified metal-organic frameworks coupled with LC–MS/MS for the determination of chlorophenols from environmental water samplesM. Cai1, Q. Wang1, M. Jin2, C. Du1, C. Dong1
1 Zhejiang Gongshang University, School of Environmental Science and Engineering, Hangzhou, China; 2 Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China
104 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP3-P18-Mo - FPSE-HPLC-PDA method for the determination of twelve azole antimicrobial drug residues in human plasma and urineM. Locatelli1, A. Kabir2, S. Carradori1, E. De Luca1, D. Innosa1, T. Lopatriello1, K.G. Furton2
1 University "G. D'Annunzio" of Chieti-Pescara, Dept. Of Pharmacy, Chieti, Italy; 2 International Forensic Research Institute- Florida International University, Department of Chemistry and Biochemistry, Miami, USA
APP3-P19-Mo - Selective extraction of coumarins by using molecularly imprinted polymers. Preparation, characterization and application of sorbentsK. Hroboňová, A. MachyňákováFaculty of Chemical and Food Technology- Slovak University of Technology in Bratislava, Institute of Analytical Chemistry, Bratislava, Slovakia
APP3-P20-Mo - Influence of glass vial type upon trace level recovery rates of basic analytes by LC/MS/MSM. Kamuf1, A.G. Harder2
1 Agilent Technologies, Agilent CrossLab Group R&D, Waldbronn, Germany; 2 Agilent Technologies, Agilent CrossLab Group R&D, Englewood, USA
APP3-P21-Mo - Development of a carboxyl group derivatization LC method for monitoring the deamidation of proteinY. Sakaguchi, T. Kinumi, A. TakatsuNational Institute of Advanced Industrial Science and Technology AIST, National Metrology Institute of Japan NMIJ, Tsukuba, Japan
APP3-P22-Mo - On-line coupling of in-syringe automated dispersive liquid-liquid extraction/back-extraction to ICP-AES for elemental analysisK. Fikarová1, B. Horstkotte1, Cocovi-Solberg D.J.2, H. Sklenářová1, M. Miró2, P. Solich1
1 Univerzita Karlova- Farmaceutická fakulta Hradec Králové, Analytical chemistry, Hradec Králové, Czech Republic; 2 University of Balearic Island, Chemistry, Palma de Mallorca, Spain
APP3-P23-Mo - The selectivity of solid phase extraction (SPE) with molecularly imprinted polymers (MIPs)G. Horvai1,2, Z. Dorko1, B. Toth1
1 Budapest University of Technology and Economics, Inorganic and Analytical Chemistry, Budapest, Hungary; 2 MTA-BME, Research group of Technical Analytical Chemistry, Budapest, Hungary
APP3-P24-Mo - Comparison of novel and commercially available solid-phase extraction materials for the isolation of acidic crude oil metabolitesD. Schemeth, N. Juul Nielsen, J.H. ChristensenUniversity of Copenhagen, Department of Plant and Environmental Sciences, Frederiksberg C, Denmark
APP3-P25-Mo - Automated bundled hollow fiber-array-mediated liquid-phase microextraction of perfluorinated compoundsS. Goh1,2, H.K. Lee1,2
1 National University of Singapore, Chemistry, Singapore, Singapore; 2 National University of Singapore, Environmental Research Institute, Singapore, Singapore
APP3-P26-Mo - New improvements in bar adsorptive microextraction devices for the analysis of emerging compounds in real matricesA.H. Ide, J.M.F. NogueiraUniversidade de Lisboa, Centro de Química e Bioquímica, Lisboa, Portugal
APP3-P27-Mo - Pneumatic valves for micro-milled microfluidic devicesJ. Novotný1,2, F. Foret2
1 University of Pardubice - Faculty of Chemical Technology, Department of Biological and Biochemical Sciences, Pardubice, Czech Republic; 2 Institute of Analytical Chemistry of the CAS. v. v. i., Department of Bioanalytical Instrumentation, Brno, Czech Republic
APP3-P28-Mo - Micro-extraction by packed sorbent coupled on-line to column-switching chromatography system - a case study on determination of three beta-blockers in human urineD. Šatínský, V. SobekCharles University- Faculty of Pharmacy, Analytical Chemistry, Hradec Kralove, Czech Republic
105HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP3-P29-Mo - Flow analysis methods for sample pre-treatment and separationP. Chocholouš, D. Šatínský, P. SolichCharles University- Faculty of Pharmacy, Department of analytical chemistry, Hradec Kralove, Czech Republic
APP3-P30-Mo - Concentration of nucleic acids by coupled column capillary isotachophoresis application to circulating cell-free dna extraction from liquid biopsy samplesV. Datinska1, I. Voracova1, U. Schlecht2, J. Berka2, F. Foret1
1 Institute of Analytical Chemistry of the CAS v. v. i., Department of Bioanalytical Instrumentation, Brno, Czech Republic;
2 Roche Sequencing Solutions, Roche Sequencing Solutions, Pleasanton, USA
APP3-P31-Mo - Automated and objective analytical scale group-type separation of saturates, aromatics and resins from crude oilH.K. Bensen, S.S. Jakobsen, N.J. Nielsen, J.H. ChristensenUniversity of Copenhagen, PLEN, Frederiksberg C, Denmark
APP3-P32-Mo - Quantification and characterization of mineral oils in consumer products using comprehensive normal-phase liquid chromatography-gas chromatographyA.R. García Cicourel1, H.G. Janssen2
1 University of Amsterdam, Analytical Chemistry- Faculty of Science, Amsterdam, The Netherlands; 2 Unilever Research and Development, Central Analytical Science, Vlaardingen, The Netherlands
APP3-P33-Mo - A unified open access workflow from analysis to purification (A-->P) for medicinal chemistsL. Taylor1, S. D’Antonio2, S. Khera1, S. Hayes2, P. Zimba3, I.S. Shong3
1 Agilent, Marketing, Santa Clara, USA; 2 Agilent, Applications, Santa Clara, USA; 3 Texas A&M University, Coastal Studies, Corpus Christi, USA
APP3-P34-Mo - Simplified and reliable up-scaling for automated high-throughput purification workflowsV. Hruska, M. Renz, N. Lagouvardos, J. Steflova, V. Hruskova, F. WolfAgilent Technologies Deutschland GmbH & Co. KG, Liquid Phase Separations Division, Waldbronn, Germany
APP3-P35-Mo - Automated liquid-phase microextraction using a labmade Arduino-based cartesian robotD.A. Vargas Medina, L.F. Rodríguez Cabal, V. Missaglia, A.J. Santos NetoUniversidade de São Paulo, Instituto de Química de São Carlos, São Carlos, Brazil
APP3-P36-Mo - Microwave assisted derivatization and quantification of glyphosate, glufosinate, and aminomethylphosphonic acid by GC-MSB.B. Sliz, F. Menestrina, N.R. Ronco, C.B. Castells, L.G. GagliardiFacultad de Ciencias Exactas - UNLP-CONICET, Laboratorio de Investigación y Desarrollo de Métodos Analíticos- LIDMA., La Plata, Argentina
APP 4 MetabolomicsAPP4-P01-Mo - Practical application of solvatic sorption model for method development of phenylisothiocyanate derivatives of amino acids in human biological materialsS. Vorslova1, J. Golushko2, A. Viksna1, S. Galushko2
1 University of Latvia, Department of Analytical Chemistry, Riga, Latvia; 2 Institute of Chromatography, Riga, Latvia
APP4-P02-Mo - SPME-LC-MS: The new potential for in situ and in vivo brain tumor studiesP. Goryńska1, K. Goryński1, K. Chmara1, K. Jaroch1, D. Paczkowski2, M. Harat2, B. Bojko1
1 Faculty of Pharmacy- Nicolaus Copernicus University in Torun- Poland, Department of Pharmacodynamics and Molecular Pharmacology, Bydgoszcz, Poland; 2 The 10th Military Research Hospital and Polyclinic, Neurosurgery Unit, Bydgoszcz, Poland
APP4-P03-Mo - The use of HPLC-MS in the metabonomic analysis of chicken eggs over timeA. Johnson, D. ThompsonKeele University, School of Chemical and Physical Sciences, Newcastle-under-Lyme, United Kingdom
106 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP4-P04-Mo - The effect of freezing duration and number of freeze-thaw cycles on the metabolic profile of meatK. Sidwick, D. ThompsonKeele University, School of Chemical and Physical Sciences, Keele, United Kingdom
APP4-P05-Mo - Retention time indexing in RP-LC-MS based metabolomics for enhancing metabolite identification. A cross-lab trialM. Witting1, N. Sillner1, D. Spaggiari2, S. Rudaz2, J. Lintelmann3, J.P. Schnitzler4, O. Begou5, T. Georgios5, H. Gika5, P. Schmitt-Kopplin1, M. Quilliam6
1 Helmholtz Zentrum München, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany; 2 University of Geneva, School of Pharmaceutical Sciences-, Geneva, Switzerland; 3 Helmholtz Zentrum München, Comprehensive Molecular Analytics, Neuherberg, Germany; 4 Helmholtz Zentrum München, Research Unit Environmental Simulation, Neuherberg, Germany;
5 Aristotle University of Thessaloniki, Laboratory of Analytical Chemistry- Department of Chemistry, Thessaloniki, Greece;
6 National Research Council Canada, Measurement Science and Standards, Halifax, Canada
APP4-P06-Mo - The use of solid phase microextraction (SPME) for metabolomic analysis of cell culture after administration of combretastatin A4 phosphateK. Jaroch1, E. Boyaci2, K. Goryński1, P. Goryńska1, J. Pawliszyn2, B. Bojko1
1 Nicolaus Copernicus in Torun- Collegium Medicum in Bydgoszcz, Department of Pharmacodynamics and Molecular Pharmacology-, Bydgoszcz, Poland; 2 Department of Chemistry- University of Waterloo, Waterloo, Canada
APP4-P07-Mo - Assessing emotional states: Metabonomic profiling and quantification of a salivary biomarkerG. Romoaldo1, S. Hambye1, V. Tagliatti2, J.M. Colet2, B. Blankert1
1 UMONS - Faculty of Medecine and Pharmacy, Pharmaceutical analyses, Mons, Belgium; 2 UMONS - Faculty of Medecine and Pharmacy, Human biology and toxicology, Mons, Belgium
APP4-P08-Mo - D-2 hydroxyglutarate dehydrogenase assay reveals regulation of D-2-hydroxyglutarate degradationR. Berger, P. Oefner, K. DettmerUniversity of Regensburg, Institute of functional genomics, Regensburg, Germany
APP4-P09-Mo - Retention time indexing as an approach to standardize reporting of retention data in metabolomicsR. Stoffel1, M. Quilliam2, D. Bell3, A. Fridstrom4, M. Witting1
1 Helmholtz Zentrum München, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany; 2 National Research Council Canada, Measurement Science and Standards, Halifax- Nova Scotia, Canada; 3 Sigma-Aldrich, Supelco, Bellefonte, USA;
4 Sigma-Aldrich, Advanced Analytical Europe, St. Gallen, Switzerland
APP4-P10-Mo - Analysis of amino acids in human plasma of patients with schizophrenia by means of CE-LIF methodA. Celá1, A. Mádr1, J. Juřica2, Z. Glatz1
1 Masaryk University- Faculty of Science, Department of Biochemistry, Brno, Czech Republic; 2 Masaryk University- Faculty of Medicine, Department of Pharmacology, Brno, Czech Republic
APP4-P11-Mo - Development of an analytical workflow for the characterization of the microbiota metabolome, using a combination of NMR and MS, through targeted and untargeted approachesA. Bunescu, K. Hennig, X. Meniche, A. Ouattara, J. Abi Ghanem, E. Biliaut, F. BequetBIOASTER, Metabolomics & Proteomics unit, Lyon, France
APP4-P12-Mo - Enabling high-confidence human endogenous metabolite identification via high-resolution MS/MS retention-time libraryV. Tellström1, M. Boháč2
1 Bruker Daltonik GmbH, Applications Development, Bremen, Germany; 2 Bruker s.r.o., Sales and application, Brno, Czech Republic
APP4-P13-Mo - Targeted and untargeted metabolomic analysis in healthy subjects upon ursodeoxycholic acid exposureD.J. Kim, K. Cho, H. Chung, S.C. Ji, K.S. Yu, I.J. Jang, J.Y. ChoDepartment of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, Seoul, Republic of Korea
107HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP4-P14-Mo - ω- and ω-1 hydroxylation of medium chain fatty acid by CYP3A : Characterization of a potential novel urinary biomarker of CYP3A activityB. Kim1, B. Kim2, J. Lee2, K.S. Yu2, I.J. Jang2, J.Y. Cho2
1 Seoul national university, Clinical pharmacology and therapeutics, Seoul, Republic of Korea; 2 Seoul National University College of Medicine and Hospital, Department of Clinical Pharmacology and Therapeutics, Seoul, Republic of Korea
APP4-P15-Mo - Separation of antioxidants from biological matrices by molecularly imprinted polymer for HPLC-MS analysisJ. Vondroušová, F. Pavlíček, M. Mikoška, K. Syslová1
University of Chemistry and Technology Prague, Department of Organic Technology, Prague 6, Czech Republic
APP4-P16-Mo - Analysis of amino acids profile by capillary electrophoresis with mass spectrometryM. Skrutková Langmajerová1,2, P. Vedrová1, A. Pleskačová2,3, Z. Glatz1,2, J. Tomandl1,2,3, K. Kaňková2
1 Masaryk University, Faculty of Science - Department of Biochemistry, Brno, Czech Republic; 2 Masaryk University, Faculty of Medicine - Department of Pathological Physiology, Brno, Czech Republic; 3 Masaryk University, Faculty of Medicine - Department of Biochemistry, Brno, Czech Republic
APP4-P17-Mo - Metabolic regulation in response to activated Wnt/beta-catenin signaling pathwayS.J. Park, J.H. Kim, S. Oh, D.Y. LeeKookmin university, Bio and Fermentation Convergence Technology, Seoul, Republic of Korea
APP4-P18-Mo - Metabolic approach of autoimmune disease such as graves’ disease for plasma biofluid biomarker by using GC-MS and LC-MS/MS systemD.Y. Ji1, S.J. Park1, D. Kim2, E.J. Lee2, D.Y. Lee1
1 Kookmin University, Systemsbiology lab, Seoul, Republic of Korea; 2 Yonsei University College of Medicine, Department of Internal Medicine- Open NBI Convergence Technology Research Laboratory, seoul, Republic of Korea
APP4-P19-Mo - A simple and robust UPLC-Q-TOF-based untargeted protocol for metabolic fingerprinting of polar metabolites in perilymph using hydrophilic interaction liquid chromatographyK. Pirttilä1, J. Haglöf1, M. Engskog1, P. Videhult Pierre2, G. Laurell2, T. Arvidsson1, C. Pettersson1
1 Uppsala University, Medicinal Chemistry, Uppsala, Sweden; 2 Uppsala University, Department of Surgical Sciences, Uppsala, Sweden
APP4-P20-Mo - The perilymph metabolome, determined by UHPLC-HRMSJ. Haglöf1, M. Engskog1, K. Pirtillä1, P. Videhult-Pierre2, G. Laurell2, T. Arvidsson1, C. Pettersson1
1 Uppsala University, Medicinal Chemistry, Uppsala, Sweden; 2 Uppsala University, Surgical Sciences, Uppsala, Sweden
APP4-P21-Mo - Are your metabolomics methods producing data of high analytical quality?M. Engskog, J. Haglöf, A. Elmsjö, T. Arvidsson, C. PetterssonUppsala University, Medicinal Chemistry, Uppsala, Sweden
APP4-P22-Mo - Non-target chemical analysis of industrial processes - A way to understand and monitor end-product quality in an enzyme recovery processS.B. Knudsen1, J. Qvist2, K.B. Andersen2, N.J. Nielsen3, J.H. Christensen3
1 Novozymes/University of Copenhagen, Product and Process Development/Plant and Environmental Sciences, Bagsvaerd, Denmark; 2 Novozymes A/S, Liquid Products Development, Bagsvaerd, Denmark; 3 University of Copenhagen, Plant and Environmental Sciences, Frederiksberg C, Denmark
APP4-P23-Mo - Orbital ion-trap mass spectrometry-based analysis of microbial metabolites in amniotic fluidE. Cechova1, T. Pavlová1,2, J. Bienertová-Vašků2, I. Musilová3, M. Kacerovský3,4, J. Klánová1, Z. Spáčil11 Masaryk University, RECETOX- Faculty of Science, Brno, Czech Republic; 2 Masaryk University, Department of Pathological Physiology- Faculty of Medicine, Brno, Czech Republic; 3 University Hospital Hradec Kralove, Department of Obstetrics and Gynecology- Charles University Faculty of Medicine in Hradec Kralove, Hradec Králové, Czech Republic; 4 University Hospital Hradec Kralove, Biomedical Research Center, Hradec Králové, Czech Republic
APP4-P24-Mo - Applicability of SFC-MS to metabolomics: Which kind of analytes can be successfully analyzed?V. Desfontaine, J.L. Veuthey, D. GuillarmeUniversity of Geneva, Analytical Sciences, Genève, Switzerland
108 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP4-P25-Mo - Mass-spectrometric-imaging of living cells: Challenges, solutions, and perspectiveA. SvatosMax Planck Institute for Chemical Ecology, Mass spectrometry/Proteomics, Jena, Germany
APP 5 Chiral separationsAPP5-P01-Tu - The use of orthogonal methods to monitor the major degradation products of cannabidiol (CBD)C. Layton, J. Runco, A. AubinWaters Corp, Separations, Milford, USA
APP5-P02-Tu - Chiral separation of aryloxyphenoxy-propionate herbicides in a permethyl-β-cyclodextrin based column. Influence of temperature and mobile phase composition on selectivityJ. Padro1, E. Lubomirsky1, H. Di Loreto2, C. Castells1
1 Laboratorio de Investigación y Desarrollo de Métodos Analíticos and División Química Analítica- Facultad de Ciencias Exactas- UNLP, Chemistry, La Plata, Argentina; 2 Agrofina S. A.- Laboratorio de Desarrollo Analítico, Ciudad Autónoma de Buenos Aires, Argentina
APP5-P03-Tu - SFC in chiral separations: Evaluation of equivalency of polysaccharide enantioselective stationary phasesP. Jakubec1, M. Douša2, L. Nováková1
1 Faculty of pharmacy in Hradec Kralove- Charles University, Department of analytical chemistry, Hradec Kralove, Czech Republic; 2 Zentiva k.s., Prague, Czech Republic
APP5-P04-Tu - Enantioseparation of liquid-crystalline materials by chiral HPLC: Development of the method for various types of functional materialsT. Vojtylová1,4, M. Zurowska2, Z. Galewski3, I. Korbecka3, V. Hamplová1, D. Sykora4
1 Institute of Physics, The Czech Academy of Sciences, Chemistry, Prague, Czech Republic; 2 Military University of Technology, Faculty of Advanced Technologies and Chemistry, Warsaw 46, Poland; 3 University of Wroclaw, Faculty of Chemistry, Wrocław, Poland; 4 University of Chemistry and Technology, Department of Analytical Chemistry, Prague 6 – Dejvice, Czech Republic
APP5-P05-Tu - Natural cannabinoids analysis by a chemo-enantioselective separation method in eUHPSFC-MS using the new UHPC-Whelk-O1 sub 2 µm CSPG. Mazzoccanti1, O.H. Ismail1, A. Ciogli1, C. Villani1, C. Manzo2, S. Anderson3, F. Gasparrini11 University of Roma La Sapienza, Dipartimento di chimica e tecnologia del farmaco, Roma, Italy; 2 Avantech Group S.r.l., Angri, Italy; 3 Regis Technologies, Morton Grove, USA
APP5-P06-Tu - Chiral stationary phase optimized selectivity supercritical fluid chromatography (SOS-SFC): A novel approach for optimizing the separation of enantiomersF. Lynen, R. Szucs, R. HegadeGhent University, Faculty of Sciences, Ghent, Belgium
APP5-P07-Tu - Open access chiral chromatography: Isomers-a-la-carteM.L. de la Puente, A.S. MarínEli Lilly and Company, Analytical Technologies _Discovery Chemistry Research and Technologies, Alcobendas Madrid, Spain
APP5-P08-Tu - Chiral separation of amphetamine using UPLC-MS/MS in a clinical laboratoryP. HardenkloNU-sjukvarden, Laboratoriemedicin, Trollhättan, Sweden
APP5-P09-Tu - Development and usage of a comprehensive parallel chiral HPLC stationary phase screen in polar organic solvents for drug discovery chemistryA. Knaggs1, T. Underwood1, R. Stimpson2, Y. Iwata3
1 GlaxoSmithKline R&D, Discovery Analytical, Stevenage, United Kingdom; 2 Shimadzu UK Limited, Technology Support, Milton Keynes, United Kingdom; 3 Shimadzu Corporation Japan, LC Business Unit, Seika-cho- Soraku-gun, Japan
109HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP5-P10-Tu - HPLC enantioseparation of carbocyclic β-amino acids possessing limonene skeleton on macrocyclic glycopeptide-based chiral stationary phasesI. Ilisz1, A. Bajtai1, Z. Szakonyi2, F. Fülöp2, D. Armstrong3, A. Péter1
1 University of Szeged, Inorganic and Analytical Chemistry, Szeged, Hungary; 2 University of Szeged, Institute of Pharmaceutical Chemistry, Szeged, Hungary; 3 University of Texas at Arlington, Department of Chemistry and Biochemistry, Arlington, USA
APP5-P11-Tu - Application of Cinchona alkaloid-based chiral stationary phases for the enantioseparation of limonene-based β-amino acidsA. Péter1, N. Grecsó1, G. Lajkó2, Z. Szakonyi2, F. Fülöp2, W. Lindner3, I. Ilisz1
1 University of Szeged, Department of Inorganic and Analytical Chemistry, Szeged, Hungary; 2 University of Szeged, Institute of Pharmaceutical Chemistry, Szeged, Hungary; 3 University of Vienna, Department of Analytical Chemistry, Vienna, Austria
APP5-P12-Tu - Effects of N-substitution on the elution order of cyclic ß3-amino acid enantiomers on Cinchona alkaloid-based zwitterionic and anion exchanger-type chiral stationary phasesT. Orosz1, A. Péter1, F. Fülöp2, W. Lindner3, I. Ilisz1
1 University of Szeged, Department of Inorganic and Analytical Chemistry, Szeged, Hungary; 2 University of Szeged, Institute of Pharmaceutical Chemistry, Szeged, Hungary; 3 University of Vienna, Department of Analytical Chemistry, Vienna, Austria
APP5-P13-Tu - An overloading study on zwitterionic chiral stationary phasesI. Bacskay1, B. Varga2, W. Lindner3, A. Felinger1,2
1 MTA-PTE, Molecular Interactions in Separation Science Research Group, Pécs, Hungary; 2 University of Pécs, Department of Analytical and Environmental Chemistry and Szentágothai Research Center, Pécs, Hungary; 3 University of Vienna, Institute of Analytical Chemistry, Vienna, Austria
APP5-P14-Tu - Evaluation of chiral stationary phases for the separation of the pesticide fipronil and its main metabolites by HPLC-UVD.B. Carrão, I.C.D.R. Gomes, A.R.M. de OliveiraUniversidade de São Paulo, Chemistry Department, Ribeirão Preto, Brazil
APP5-P15-Tu - HPLC analysis of folate appended cyclodextrinsJ. Szemán1, K. Csabai1, E. Varga1, M. Malanga1, K. Ludányi2, L. Szente1
1 CycloLab Ltd., Research & Development Laboratory, Budapest, Hungary; 2 Semmelweis University, Department of Pharmaceutics- Faculty of Pharmacy, Budapest, Hungary
APP5-P16-Tu - Quantitative determination of chiral amino acid species in therapeutic peptidesG. Trausinger, F. Sinner, C. MagnesJoanneum Research Forschungsgesellschaft mbH, Health - Institute for Biomedicine and Health Sciences, Graz, Austria
APP5-P17-Tu - Enantioseparation of cathinones and their metabolites on chiral zwitterion ion-exchange stationary phase using gradient SFC-MSM. Kohout1, N. Kolderová2, B. Jurásek2, W. Lindner3
1 University of Chemistry and Technology Prague, Department of Organic Chemistry, Prague, Czech Republic; 2 University of Chemistry and Technology Prague, Forensic laboratory of biologically active substances, Prague, Czech Republic; 3 University of Vienna, Institute of Analytical Chemistry, Vienna, Austria
APP5-P18-Tu - Enantiomeric separations of chiral amino acids with carboxylated crown ethers by CE-MSS. Lee1,2, J.H. Lee1,2, S.J. Kim2,3, Y.C. Na1,2
1 Ewha Womans University, Chemistry and Nano Science, Seoul, Republic of Korea; 2 Korea Basic Science Institute, Western Seoul Center, Seoul, Republic of Korea; 3 Ewha Womans University, Food Science and Engineering, Seoul, Republic of Korea
APP5-P19-Tu - Enantiorecognition properties of helical dicationsD. Koval, H. Talele, L. Severa, P.E. Reyes-Gutiérrez, J. Vávra, F. Teplý, V. KašičkaUOCHB AVČR v.v.i., x, Praha 6 - Dejvice, Czech Republic
APP5-P20-Tu - Screening chiral compounds using superficially porous based chiral columns and the agilent method development solutionW. Long, A. Mack, A. Bivens, J. LinkAgilent Technologies, CSD, Wilmington, USA
110 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP5-P21-Tu - Evaluation of chiral stationary phases for the resolution of the fungicide tebuconazole and its main metabolite tebuconazole-1-hydroxy by HPLC-DADM.D. Habenschus, N.C. Perez de Albuquerque, A.R. Moraes de OliveiraUniversidade de São Paulo, Chemistry, Ribeirão Preto, Brazil
APP5-P22-Tu - Chiral stationary-phase optimized selectivity liquid chromatography: A novel approach for the separation of mixtures of enantiomersR. Hegade1, M. De Beer2, F. Lynen1
1 Ghent University- Belgium, Separation Science Group- Department of Organic & Macromolecular chemistry- Faculty of Sciences- Ghent University, Ghent, Belgium; 2 AmatsiSEPS, Research and development, Ghent, Belgium
APP5-P23-Tu - Validation of an enantioselective LC-MS/MS method in polar organic mode for the analysis of the pesticide myclobutanil in human liver microsomesF.S. Fonseca1, D. Carrão1, R.M. da Silva2, A.R.M. de Oliveira1
1 Universidade de São Paulo, Chemistry Department, Ribeirão Preto, Brazil; 2 Núcleo de Pesquisas em Produtos Naturais e Sintéticos, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Ribeirão Preto, Brazil
APP5-P24-Tu - In vitro enantioselective inhibition of human cytochrome P450 enzymes by the pesticide fenamiphosN.C. Perez de Albuquerque1, C. Masetto de Gaitani2, B. Alves Rocha3, F. Barbosa Júnior3, A.R. Moraes de Oliveira1
1 Universidade de São Paulo, Chemistry, Ribeirão Preto, Brazil; 2 Universidade de São Paulo, Pharmaceutical Sciences, Ribeirão Preto, Brazil; 3 Universidade de São Paulo, Clinical Analysis- Toxicology and Food Science, Ribeirão Preto, Brazil
APP 6 LipidomicsAPP6-P01-Tu - Plasma lipidomics reveals perturbed lipid metabolism and identifies potential lipid biomarkers of human colorectal cancerS. Sensen1, Y. Li1, L. Linnan1, C. Chun2, B. Yu1, L. Huwei11 Peking University, College of Chemistry and Molecular Engineering, Beijing, China; 2 Guangdong Medical University- Zhanjiang, Analytical Center, Zhanjiang, China
APP6-P02-Tu - Localization of lipids’ double bond position by means of post column Paternὸ Büchi derivatization and tandem mass spectrometryV. Jeck, H. HayenUniversity of Münster, Institute of Inorganic and Analytical Chemistry, Münster, Germany
APP6-P03-Tu - Targeted lipidomics profiling of acute arsenic exposure in mice serum by on-line solid-phase extraction stable-isotope dilution liquid chromatography-tandem mass spectrometryC.Y. Chen1, P. Lin2, M.H. Tsai2, H.L. Lee1
1 Fu Jen Catholic University, Department of Chemistry, New Taipei City, Taiwan- Province of China; 2 National Health Research Institutes, National Institute of Environmental Health Sciences, Miaoli County, Taiwan- Province of China
APP6-P04-Tu - Comparison of one-phase vs two-phase extractions for untargeted lipidomicsA. Gil1, W. Zhang2, K. Wolters2, H. Permentier3, T. Boer4, R. Heiner-Fokkema4, D.J. Reijngoud2, R. Bischoff1
1 University of Groningen, Analytical Biochemistry, Groningen, The Netherlands; 2 University Medical Center Groningen, Department of Pediatrics, Groningen, The Netherlands; 3 University of Groningen, Interfaculty Mass Spectrometry Center, Groningen, The Netherlands; 4 University Medical Center Groningen, Department of Laboratory Medicine- Laboratory of Metabolic Disease, Groningen, The Netherlands
APP6-P05-Tu - MALDI Orbitrap mass spectrometry profiling of dysregulated sulfatides in kidney tissue and plasma samples of patients with renal cell carcinomaR. Jirásko1, M. Holčapek1, M. Khalikova1, D. Vrána2, V. Študent3, B. Melichar2
1 University of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic; 2 Palacký University- Faculty of Medicine and Dentistry, Department of Oncology, Olomouc, Czech Republic; 3 Palacký University- Faculty of Medicine and Dentistry, Department of Urology, Olomouc, Czech Republic
APP6-P06-Tu - Fingerprinting of plasma lipids by two "alternative" methods, SFC-HRMS and UHPLC-HRMSV. Kosek1, M. Hajsl2, M. Maly2, J. Hajslova1
1 UCT Prague, Department of food analysis and nutrition, Prague, Czech Republic; 2 Military University Hospital Prague, Department of Cardiology, Prague, Czech Republic
111HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP6-P07-Tu - Do commercial bumblebees represent a threat for local subspecies?E. Kofroňová1, A. Votavová2, O. Komzáková2, P. Jedlička3, I. Valterová1
1 IOCB AS CR, Infochemicals, Prague, Czech Republic; 2 Agricultural Research- Ltd., Department of genetic sources, Troubsko, Czech Republic; 3 IOCB AS CR, Chemistry of social insects, Prague, Czech Republic
APP6-P08-Tu - Relative quantification of lipids by using metabolic heavy water labelingT.Y. Kim1,2, J. Kim2
1 Gwangju Institute of Science and Technology, School of Earth Sciences and Environmental Engineering, Gwangju, Republic of Korea; 2 Gwangju Institute of Science and Technology, Department of Chemistry, Gwangju, Republic of Korea
APP6-P09-Tu - Lipidomic investigation of Fenclozic acid and Sitaxentan treated PXB-mice using a new scanning quadrupole UPLC-QTof MS acquisition modeI.D. Wilson1, A. King1, M. Baginski2, Y. Morikawa2, R. Plumb1
1 Imperial College, Surgery and Cancer, London, United Kingdom; 2 PhoenixBio USA Corp., n/a, New York, USA
APP 7 Affinity separationsAPP7-P01-Tu - Monodisperse-porous titania microspheres with biomodal pore-size distribution as a new stationary phase for DNA microextractionM. Durmaz1,2, D.D. Usta3,4, K. Salimi1, A. Kuban1, A. Tuncel11 Hacettepe University, Chemical Engineering Department, Ankara, Turkey; 2 Cankiri Karatekin University, Chemical Engineering Department, Cankiri, Turkey; 3 Gazi University, Department of Medical Biology and Genetics, Ankara, Turkey; 4 Istanbul Medeniyet University, Department of Medical Biology, Istanbul, Turkey
APP7-P02-Tu - Fabrication of biomolecule containing multi-channel photonic crystal fibres, and their application to bio-affinity and bio-catalytic reactionsS. Currivan1, N. Upadhyay1, B. Paull1,2
1 Australian Centre for Research on Separation Science, School of Physical Sciences, Hobart-, Australia; 2 ARC Centre of Excellence for Electromaterials Science, School of Physical Sciences, Hobart-, Australia
APP7-P03-Tu - Development of purification method for proteins utilizing temperature-responsive affinity chromatographyK. Ikeda, M. Akimaru, Y. Hiruta, K. Nagase, H. KanazawaKeio University, Faculty of Pharmacy, Tokyo, Japan
APP7-P04-Tu - The influence of several drugs on displacement of l tryptophan and lidocaine from binding sites on albuminH. Nevídalová, L. Michalcová, Z. GlatzMasaryk University, Biochemistry, Brno, Czech Republic
APP7-P05-Tu - Affinity capillary electrophoresis as fast screening method for the identification of potentially active compounds for DM1 treatmentI. Neaga1, S. Hambye1, E. Bodoki2, C. Palmieri1, E. Ansseau3, B. Blankert1, R. Oprean2
1 University of Mons, Laboratory of Pharmaceutical Analysis, Mons, Belgium; 2 Iuliu Hatieganu University of Medicine and Pharmacy, Analytical Chemistry Department, Cluj-Napoca, Romania; 3 University of Mons, Laboratory of Molecular biology, Mons, Belgium
APP7-P06-Tu - Insight into drug-protein interactions with using different techniquesL. Michalcová, H. Nevidalová, Z. GlatzFaculty of Science- Masaryk University, Department of Biochemistry, Brno, Czech Republic
APP7-P07-Tu - Aptamer selection by capillary electrophoresis and next generation sequencing for therapeutic target protein vitronectinC. Colyer1, W. Gmeiner2, K. Riley3, C. Stuart4
1 Wake Forest University, Chemistry, Winston-Salem, USA; 2 Wake Forest University, Cancer Biology, Winston-Salem, USA;
3 Swarthmore College, Chemistry & Biochemistry, Swarthmore, USA; 4 RayBiotech- Inc., Scientist & Project Manager, Norcross, USA
APP 8 Glycomics and glycoproteomics – celebrating Miloš Novotný 75th birthdayAPP8-P01-Tu - Glycoprotein monosaccharide analysis using HPAE-PAD for biopharmaceutical quality controlS. Patil, A. Semyonov, S. Guazzotti, J. RohrerThermo Fisher Scientific, Sunnyvale, CA, USA 94085
112 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP8-P02-Tu - Cysteine-functionalized metal-organic framework: Facile synthesis and high efficient enrichment of N-linked glycopeptides in cell lysate biosampleM. Wen, X. Linnan, L. Xianjiang, L. Huwei, B. YuPeking University, College of chemistry and engineering, Beijing, China
APP8-P05-Tu - Cationic charge labeling for CE-MS analysis of oligosaccharidesJ. Krenkova, J. Partyka, R. Cmelik, F. ForetInstitute of Analytical Chemistry of the CAS v.v.i., Bioanalytical Instrumentation, Brno, Czech Republic
APP8-P06-Tu - N-Glycan analysis by orthogonal methods: UHPLC and multi-capillary CEB. Kunnummal, A. EckardThermo Fisher Scientific, Pharma Analytics, South San Francisco, USA
APP8-P07-Tu - Sensitive detection of sialylated n-glycans using optimized HILIC LC-MS separationsQ. Wang, M. LauberWaters Corporation, Consumables Group, Milford, USA
APP8-P08-Tu - Fluorescent and MS-Active labeling reagent for the analysis of n-glycansD. Brousmiche1, M. Lauber1, Q. Wang1, S. Koza2, Y.Q. Yu2
1 Waters Corporation, Consumables Group, Milford, USA; 2 Waters Corporation, Scientific Operations, Milford, USA
APP8-P09-Tu - Analysis of cetuximab glycosylation using multiple fractionation methods and CE-MS profilingC. Váradi, S. Mittermayr, J. BonesNational Institute for Bioprocessing Research and Training, Characterisation and Comparability Laboratory, Dublin, Ireland
APP8-P10-Tu - A simple method to achieve rapid and complete deglycosylation of glycoproteins with complex glycansA. Eckard, D.R. Dupont, B. Kunnummal, J. Young, P.A. BellThermo Fisher Scientific, South San Francisco, USA
APP 9 Recent advances in (bio)pharmaceuticals I.APP9-P01-We - Novel application of standard chromatographic tests of stationary phase characterization in industrial scale HPLC processesI. SallayChromatography, Osaka, Japan
APP9-P02-We - Development and validation of platform chromatography methods for biologicsA. MalekGenentech, Analytical Development and Quality Control, South Sanfrancisco, USA
APP9-P03-We - Development of QC-friendly 2D-LC methods in pharmaceutical laboratoriesK. Chen, P. Yogendrarajah, W. Peijs, J.P. Boon, M. HellingsJanssen- Pharmaceutical Companies of Johnson & Johnson, PDMS-AD-SMMD, Beerse, Belgium
APP9-P04-We - Tracking and reporting synthetic peptide impurities with a cost-effective single quadrupole mass detector for improved confidence in analysisB. Koshel, R. Birdsall, Z. Ximo, W. Alley, J. Fang, A. Chakraborty, Y. Ying QingWaters Corporation, Milford, USA
APP9-P05-We - Investigation of influencing factors for trace level of methyl p-toluenesulfonate control in pharmaceutical with gas chromatography coupled with mass chromatography detectionD.Y. Chen, H. Hai-yunShanghai Institute of Materia Medica- CAS, Pharmaceutical Analysis, Shanghai, China
APP9-P06-We - An informatics based approach to developing a stability indicating methodD. McLean, A. Anderson, T. SalbertAdvanced Chemistry Development ACD/Labs, Toronto, Canada
113HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP9-P07-We - Recent advances on the oxidative biotransformation of several beta-blockersR. Chira1, E. Bodoki1, V. Sándor2, M. Fillet3, F. Kilár2, B. Blankert4, R. Oprean1
1 “Iuliu Hatieganu” University of Medicine and Pharmacy, Analytical Chemistry Department, Cluj-Napoca, Romania; 2 University of Pécs, Institute of Bioanalysis, Pécs, Hungary; 3 University of Liège- CIRM, Laboratory for the Analysis of Medicines LAM- Department of Pharmacy, Liège, Belgium; 4 University of Mons- Research Institute for Health Sciences and Technology, Laboratory of Pharmaceutical Analysis - Faculty of Medicine and Pharmacy, Mons, Belgium
APP9-P08-We - High throughput LC/MS purification of pharmaceutical impuritiesF. Rieck, R. Guilliet, S. UllrichAgilent Technologies, Waldbronn, Germany
APP9-P09-We - Efficient method for the obtaining of recombinant human apoptosis signal-regulating kinase 1 (ASK1) in Escherichia coliO. Gorbatiuk1, G. Volynets1, U. Mariya2, S. Yarmoluk1
1 Institute of Molecular Biology and Genetics of NASU, Kyiv, Ukraine; 2 The State Institute of Genetic and Regenerative Medicine- NAMS of Ukraine, Kyiv, Ukraine
APP9-P10-We - Development of a supercritical fluid chromatographic system to predict the skin permeability of pharmaceutical compoundsY. Grooten, D. Mangelings, Y. Vander HeydenVrije Universiteit Brussel VUB, Department of Analytical Chemistry and Pharmaceutical Technology, Jette, Belgium
APP9-P11-We - Enantioselective separation and analysis of six ketamine metabolites using capillary electrophoresis with sulfated β-cyclodextrin and highly sulfated γ-cyclodextrinF. Sandbaumhüter1, R. Theurillat2, W. Thormann2
1 University of Bern, Clinical Pharmacology Laboratory, Bern, Switzerland; 2 University of Bern, Bern, Switzerland
APP9-P13-We - Analysis of morphine in mouse plasma by microchip electrophoresis-electrochemical detectionE. Ollikainen1, M. Koburg1, T. Aitta-aho2, R. Kostiainen1, T. Sikanen1
1 Faculty of Pharmacy- University of Helsinki, Division of Pharmaceutical Chemistry and Technology, Helsinki, Finland; 2 Faculty of Medicine- University of Helsinki, Pharmacology, Helsinki, Finland
APP9-P14-We - Separation of impurities from a fully phosphothioated and 2’-O-methylated RNA using ion-pair reversed-phase chromatographyJ. Baek1, J. Thayer1, S. Lin1, X. Liu1, R. van Ling2
1 Thermo Fisher Scientific, R&D, Sunnyvale, USA; 2 Thermo Fisher Scientific, Breda, The Netherlands
APP9-P15-We - Separation and characterization of NIST monoclonal antibody standard using a suite of chromatographic methodsI. Birznieks1, S. Bechler2, J. Baek2, X. Liu2, S. Lin2
1 Thermo Fisher Scientific, Product Management, Sunnyvale, USA; 2 Thermo Fisher Scientific, Research and Development, Sunnyvale, USA
APP9-P16-We - Advanced topics in peptide mapping: Developing reproducible high resolution separationsP. Jayaraman, S. Koza, C. Reed, H. Yang, E. ChambersWaters Corporation, Consumables Group, Milford, USA
APP9-P17-We - Successfully developing and using ultra-high performance size-exclusion chromatography (UHP-SEC) methods for the analysis of biotherapeutic proteinsS. Koza1, P. Jayaraman2, E. Chambers1
1 Waters Corp., Scientific Operations, Milford, USA; 2 Waters Corp., Consumables Group, Milford, USA
APP9-P18-We - Fraction collection for isolating impurities in forced degradation studiesP. Hong, P. McConvilleWaters Corporation, Separations Marketing Laboratory, Milford, USA
APP9-P19-We - Quantitative impurity analysis of pharmaceutical compounds by heart-cutting two-dimensional liquid chromatographyQ. Wang, L. He, J. Shackman, B. KleintopBristol-Myers Squibb, Chemical and Synthetic Development, New Brunswick- NJ, USA
114 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP9-P20-We - LC-MS/MS method for simultaneous determination of fingolimod (FTY720) and fingolimod phosphate (FTY720-P) in human bloodD. Iaroshenko, A. Piven, A. Grigoriev, A. SidorovaBioanalytical Laboratory CSU "Analytical Spectrometry", Peter the Great St. Petersburg Polytechnic University, Saint-Petersburg, Russian Federation
APP9-P21-We - The methods for determination of drug combinations in human plasma by LC-MS/MSA. Nikitina, A. Grigoriev, A. SidorovaBioanalytical Laboratory CSU "Analytical Spectrometry", Peter the Great St. Petersburg Polytechnic University, Saint-Petersburg, Russian Federation
APP9-P22-We - High-performance liquid chromatography (HPLC) of pharmaceutical oligonucleotides in non-clinical toxicology researchS. Zhao, A. Aissaoui, Y. Danilova, D. Guérette, A. Kotbi, D. Roman, D. YaalaouiCharles River Laboratories, Laboratory Sciences, Senneville, Canada
APP9-P23-We - High-resolution sampling 2D-LC for pharmaceutical impurity analysis - detection of impurities hidden under the API peak at relevant levelsS. Jung, S. Stephan, S. KriegerAgilent Technologies, LPSD, Waldbronn, Germany
APP9-P24-We - Quality control of insulin formulations: API, protamine and aggregates follow-upA. Demelenne, A. Napp, C. Lamalle, A.C. Servais, M. FilletLaboratory for the Analysis of Medicines, Department of Pharmacy - CIRM - University of Liège, Liège, Belgium
APP9-P25-We - Application of CE-C4D for beta-secretase activity assayA. Mádr, A. Celá, Z. GlatzMasaryk University - Faculty of Science, Department of Biochemistry, Brno, Czech Republic
APP9-P26-We - Quantitation of APIs and impurities in multi-component drugs by ternary gradient reversed phase chromatography with charged aerosol detectionM. De Pra, K. Lovejoy, F. SteinerThermo Fisher Scientific, Chromatography & Mass Spectrometry, Germering, Germany
APP9-P27-We - In vitro inhibition of cytochrome P450 isoforms by yangambin and its isomer, epi-yangambin, a natural product with anti-leishmanial activityJ. Martins1, F. Marquele-Oliveira2, A.A. Berretta2, A.R.M. de Oliveira3
1 School of Pharmaceutical Sciences of Ribeirao Preto, Pharmaceutical Sciences, Ribeirão Preto, Brazil; 2 Apis Flora Industrial e Comercial Ltda, Research, Ribeirão Preto, Brazil; 3 Faculdade de Filosofia Ciências e Letras de Ribeirão Preto, Química, Ribeirão Preto, Brazil
APP9-P28-We - Characterization of mercury-binding proteins in human neuroblastoma SK-N-SH cells with immobilized metal ion affinity chromatographyB. He, Y. Li, L. Hu, G. JiangState Key Laboratory of Environmental Chemistry and Ecotoxicology- Research Center for Eco-Environmental Sciences- Chinese Academy of Sciences, Beijing, China
APP 10 Recent advances in (bio)pharmaceuticals II.APP10-P01-We - In-silico development of a chromatographic method for the analysis of stability samples of a highly potent oncology candidateC. Brunelli, R. Szűcs, D. HendersonPfizer inc., Analytical Research and Development, Sandwich, United Kingdom
APP10-P02-We - High precision, automated peptide mapping of proteins by LC-MS and LC-UVM. OliverThermo Fisher Scientific, CCS, Runcorn, United Kingdom
115HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP10-P03-We - Separation and quantitative assessment of immunologically active hemagglutinin content in trivalent and quadrivalent influenza vaccinesB. Lorbetskie1, M. Lemieux1, N. Fortin1, L. Durno1, A. Farnsworth1, M. Gilbert2, C. Li3, X. Li1, M. Girard1, S. Sauve1
1 Health Canada, Centre for Biologics Evaluation, Ottawa, Canada; 2 National Research Council Canada, Human Health Therapeutics, Ottawa, Canada; 3 National Institutes for Food and Drug Control of China, Institute for Biological Product Control, Beijing, China
APP10-P04-We - Capillary electrophoresis-integrated immobilized enzyme reactor for screening of β-secretase inhibitors - potential anti-Alzheimer’s disease drugsJ. Schejbal, Š. Šefraná, Z. GlatzMasaryk University- Faculty of Science, Department of Biochemistry, Brno, Czech Republic
APP10-P05-We - Development of thiol-ene-based enzymatic microreactor array for drug metabolism studyJ. Prikryl1,2, J.P. Lafleur2, F. Foret1, P. Ertl21 Institute of Analytical Chemistry of the CAS- v. v. i., Dept. of Bioanalytical Instrumentation, Brno, Czech Republic; 2 Institute of Applied Synthetic Chemistry- Faculty of Technical Chemistry- Vienna University of Technology, Cell Chip Group, Vienna, Austria
APP10-P06-We - Unique coupling of size exclusion chromatography to mass spectrometry for the analysis of proteins and antibodies using a novel mobile phase compositionC. Muraco1, D. Bell1, A. Fridstrom2
1 MilliporeSigma, Workflow R&D, Bellefonte, USA; 2 MilliporeSigma, Technical Marketing, St. Gallen, Switzerland
APP10-P07-We - Bioanalytical evaluation of new analogues of cardioprotective drug – dexrazoxaneH. Piskáčková1, J. Bureš1, P. Reimerová1, G. Karabanovich2, J. Roh2, E. Jirkovský3, M. Štěrba3, P. Kovaříková1
1 Faculty of Pharmacy- Charles University, Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Hradec Králové, Czech Republic; 2 Faculty of Pharmacy- Charles University, Department of Organic and Bioorganic Chemistry, Hradec Králové, Czech Republic; 3 Faculty of Medicine in Hradec Kralove- Charles University, Department of Pharmacology, Hradec Králové, Czech Republic
APP10-P08-We - Application of liquid chromatography to the post-marketing quality surveillance of medicines and health products dispensed by belgian pharmacistsJ. Verrax, A.M. Gruyters, J. Corthout, S. SarreSCM-DGO, Belgian Pharmaceutical Association, Brussels, Belgium
APP10-P09-We - LC-MS/MS methods for the screening of antibiotic residues in meat: A collaborative study using spiked muscle materialsB. Roudaut, E. DubreilANSES, Laboratoire de Fougeres, FOUGERES, France
APP10-P10-We - Application of capillary electrophoresis for β-secretase inhibitor screening - development and comparison of two on-line methodsR. Řemínek, L. Slezáčková, J. Schejbal, Z. GlatzMasaryk University, Department of Biochemistry- Faculty of Science, Brno, Czech Republic
APP10-P11-We - In vitro bioactivation study of a pro-drug sobuzoxane in plasma and cardiac cellsP. Reimerová1, A. Jirkovská2, H. Piskáčková1, G. Karabanovich3, J. Roh3, P. Kovaříková1
1 Faculty of Pharmacy- Charles University, Department of Pharmaceutical Chemistry and Pharmaceutical Analysis, Hradec Králové, Czech Republic; 2 Faculty of Pharmacy- Charles University, Department of Biochemical Sciences, Hradec Králové, Czech Republic; 3 Faculty of Pharmacy- Charles University, Department of Organic and Bioorganic Chemistry, Hradec Králové, Czech Republic
APP10-P12-We - HPLC-MS characterization of transition metal complexes as potential antiproliferative drugsJ. Svoboda, L. Vaneková, K. SyslováUCT Prague, Department of Organic Technology, Prague, Czech Republic
116 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP10-P13-We - Application of LC-MS/MS to in vitro profiling of microbial-derived metabolites of chlorogenic, caffeic and ferulic acidsM. Gwiazdon1, J. Gasik1, D. Korsak2, M. Biesaga1
1 University of Warsaw, Department of Chemistry, Warsaw, Poland; 2 University of Warsaw, Department of Biology, Warsaw, Poland
APP10-P14-We - HILIC separation of mAb glycopeptides with UV, fluorescence and MS detectionM. De Pra, A. Ley, M. SamonigThermo Fisher Scientific, Chromatography & Mass Spectrometry, Germering, Germany
APP10-P15-We - Separation of bispecific mAbs using hydrophobic interaction chromatography (HIC)A. Schwahn1, J. Baek2, S. Lin2, X. Liu2
1 Thermo Fisher Scientific, CMD, Reinach, Switzerland; 2 Thermo Fisher Scientific, CMD Life Science, Sunnyvale CA, USA
APP10-P16-We - Method development and validation study for quantitative determination of captopril in pharmaceuticals by UHPLCL. Logoyda1, D. Korobko1, S. Kovalenko2, N. Zarivna1, O. Polyauk1
1 I. Horbachevsky Ternopil State Medical University, Pharmaceutical Chemistry, Ternopil, Ukraine; 2 Zaporozhye State Medical University, Organic and Bioorganic Chemistry, Zaporozhye, Ukraine
APP10-P17-We - Improvement in resolution and throughput on SEC analysis of monoclonal antibodies by using the new YMC-Pack Diol UHPLC columnF. Becker, A. Bergmann, D. EsserYMC Europe, Sales and Marketing, Dinslaken, Germany
APP10-P18-We - An interactive spreadsheet-based approach to simplify method transfer between different vendor UHPLC / HPLC instrumentsA. McKeownAdvanced Chromatography Technologies Ltd, R&D, Aberdeen, United Kingdom
APP10-P19-We - Development of fast stability indicating HPLC method for the determination of febuxostat and its impuritiesL. Belhassan1, S. Tandel1, R. Klinkenberg2, B. Streel2, F. Vanderbist1
1 Laboratoires SMB S.A., Research & Development, Brussels, Belgium; 2 Galephar M/F, Research & Development, Marche-en-Famenne, Belgium
APP10-P20-We - Automated amino acid analysis for biopharma applications using advancebio AAA superficially porous high pH stable reversed-phase columnsS. Palaniswamy1, L. Lloyd2
1 Agilent Technologies Inc, CSD PLBC, Bangalore, India; 2 Agilent Technologies Inc- Church Stretton- UK, Csd, Church Stretton, United Kingdom
APP10-P21-We - Charge heterogeneity analysis of intact monoclonal antibodies using CESI-MSJ. Thorn1, E. Candish2, C. Loessner3, S. Lock1, B. Fonslow2
1 Sciex, Separations, Warrington, United Kingdom; 2 Sciex, Separations, Brea, USA; 3 Sciex, Separations, Darmstadt, Germany
APP10-P22-We - Acitivity of skin fibroblast elestase was online monitored by capillary electrophoresisM. Skrutková Langmajerová1, L. Mijouin2, C. Pichon2, Z. Glatz1, P. Morin3, R. Nehmé3
1 Masaryk University, Department of Biochemistry, Brno, Czech Republic; 2 University of Orleans and the French National Center for Scientific Research, Center for Molecular Biophysics, Orleans, France; 3 University of Orleans and the French National Center for Scientific Research, Institute of Organic and Analytical Chemistry, Orleans, France
APP10-P23-We - A new method for analyzing MSe/All ions fragmentation in xenobiotic metabolism studiesG. Cimpan1, R. Lee2, V. Lashin3, A. Sakarov3, A. Paramonov3
1 ACD/LABS, Sales, Bracknell, United Kingdom; 2 ACD/LABS, Solution development, Toronto, Canada; 3 ACD/LABS, Software development, Toronto, Canada
117HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP10-P24-We - Lifetime stability of size exclusion chromatography columns for protein aggregate analysisR. Moore1, A. Farrell2, A. Ley3, M. De Pra3, F. Steiner3, J. Bones2
1 Thermo Fisher Scientific, Chromatography and Mass Spectrometry, Hemel Hempstead, United Kingdom; 2 National Institute for Bioprocessing Research and Training, Characterisation and Comparability Laboratory, Blackrock, Ireland; 3 Thermo Fisher Scientific, Chromatography and Mass Spectrometry, Germering, Germany
APP10-P25-We - An improved design to capture magnetic microparticles with immobilized flavin monooxygenase enzyme for in-line CE in a liquid based capillary coolant systemP. Ramana1, J. Schejbal2, E. Adams1, A. Van Schepdael1, P. Augustijns1, Z. Glatz2
1 KU Leuven - University of Leuven, Department of Pharmaceutical and Pharmacological Sciences, Leuven, Belgium; 2 Masaryk University Faculty of Science, Biochemistry, Brno, Czech Republic
APP 11 Food analysisAPP11-P01-We - Optimization of a solid phase extraction procedure of capsaicinoids from paprika by hplc with fluorimetric detectionO. Monago Maraña1, M. Guzmán Becerra2, A. Muñoz de la Peña1, T. Galeano Díaz1
1 University of Extremadura, Department of Analytical Chemistry and Research Institute on Water- Climate Change and Sustainability IACYS, Badajoz, Spain; 2 University of Extremadura, Department of Analytical Chemistry, Badajoz, Spain
APP11-P02-We - Study of the glycosidic bond homolytic cleavage under a HPLC-ESI-MSD system, as a tool for the identification of new acylated flavonol glucosides in grapes and winesG. Favre1, G. González-Neves1, D. Piccardo1, S. Gómez-Alonso2, I. Hermosín-Gutiérrez2
1 Facultad de Agronomía Universidad de la República UDELAR Uruguay, Tecnología de los Alimentos - Enología, Montevideo, Uruguay; 2 Instituto Regional de Investigación Científica Aplicada. Universidad de Castilla - La Mancha, Grupo de Investigación en Enología y Productos Naturales, Ciudad Real, Spain
APP11-P03-We - Determination of amino acid and carnosine/anserine contents of functional egg chalaza hydrolysate and its hepatoprotection against liver fibrosisY.C. Chen1, C.F. Lu1, Y.L. Lin1, J.K. Tseng2,3, C.L. Hsu4, D.J. Yang5, J.T. Lin6, C.H. Chou7,8
1 National Taiwan University, Animal Science and Technology, Taipei, Taiwan- Province of China; 2 Asia University, Optometry, Taichung, Taiwan- Province of China; 3 China Medical University Hospital, Medical Research, Taichung, Taiwan- Province of China; 4 Chung-Shan Medical University, Nutrition, Taichung, Taiwan- Province of China; 5 China Medical University, Taichung, Taiwan- Province of China; 6 Chung-Shan Medical University, Medical Applied Chemistry, Taichung, Taiwan- Province of China;
7 National Taiwan University, School of Veterinary Medicine, Taipei, Taiwan- Province of China; 8 National Taiwan University, Zoonoses Research Center, Taipei, Taiwan- Province of China
APP11-P04-We - Determination of phenolic composition of muntingia calabura linn. Fruit and its anti-inflammatory effectD.J. Yang1, J.T. Lin2, Y.Y. Chang3, Y.C. Chen4, J.K. Tseng5, H.W. Lin5
1 China Medical University, Department of Nutrition, Taichung, Taiwan- Province of China; 2 Chung Shan Medical University, Department of Medical Applied Chemistry, Taichung, Taiwan- Province of China; 3 Chung Shan Medical University, School of Medicine, Taichung, Taiwan- Province of China; 4 National Taiwan University, Department of Animal Science and Technology, Taipei, Taiwan- Province of China; 5 Asia University, Department of Optometry, Taichung, Taiwan- Province of China
APP11-P05-We - Lychee flower extract prevents selenite-induced cataract formationJ.K. Tseng1,2, Y.S. Lin3, C.C. Chen1, H.W. Lin1,2, D.J. Yang4, C.T. Lin5, Y.C. Chen6
1 Asia University, Optometry, Taichung, Taiwan- Province of China; 2 China Medical University Hospital, Medical Research, Taichung, Taiwan- Province of China; 3 Asia University Hospital, Eye Center, Taichung, Taiwan- Province of China; 4 China Medical University, Nutrition, Taichung, Taiwan- Province of China; 5 Chung Shan Medical University, Medical Applied Chemistry, Taichung, Taiwan- Province of China; 6 National Taiwan University, Animal Science and Technology, Taipei, Taiwan- Province of China
APP11-P06-We - An useful strategy based on MEPS/UHPLC combined with quality-by-design approach for foodomics applications. The case study of furanic derivatives in sugarcane honeyP. Silva1, C. L. Silva1, R. Perestrelo1, F. M. Nunes2, J. S. Câmara1
1 Madeira University, Madeira Chemistry Research Centre CQM, Funchal, Portugal; 2 Trás-os-Montes e Alto Douro University, Vila Real Chemistry Research Centre VR-CQ, Vila Real, Portugal
118 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP11-P07-We - Determination of vitamin B12 using preparative immune-affinity chromatography and UHPLCA. Schmidt, L. Call, H.K. MayerBOKU - University of Natural Resources and Life Sciences Vienna, Department of Food Science and Technology- Food Chemistry Laboratory, Vienna, Austria
APP11-P08-We - Rapid UHPLC determination of anthocyanins in acai berry and dry blueberry extractsJ. Fibigr, I. Lhotská, D. ŠatínskýCharles University- Faculty Of Pharmacy, Analytical chemistry, Hradec Králové, Czech Republic
APP11-P09-We - Nontargeted screening method for illegal additives based on ultrahigh-performance liquid chromatography–high-resolution mass spectrometryY. Fu1,2, C. Zhao1,2, Z. Zhou1,2, X. Lu1,2, G. Xu1,2
1 Dalian Institute of Chemical Physics- Chinese Academy of Sciences, Key Laboratory of Separation Science for Analytical Chemistry, Dalian, China; 2 University of Chinese Academy of Sciences, Beijing, China
APP11-P10-We - Quantitative determination of stilbenoids and proanthocyanidins on a C18-Core shell column in series with DAD and fluorescence detection and LC-MS/MS identificationD. von Baer1, V. Sáez1, S. Riquelme2, C. Gasyoso1, C. Vergara1, C. Mardones1
1 Universidad de Concepción, Departamento de Análisis Instrumental, Concepcion, Chile; 2 Universidad de Concepcion, Unidad de Desarrollo Tecnológico UDT, Coronel, Chile
APP11-P11-We - Centrifugal partition chromatographic and semi-prep isolation of oligostilbenoids from grape cane extracts and characterization by LC-MS/MS, LC-Q-TOF and NMRD. von Baer1, V. Sáez1, I. Hermosin-Gutiérrez2, C. Mardones1, C. Vergara1, L. Bustamante1, E. Pastene3, S. Gómez-Alonso2, M.V. Gómez2
1 Universidad de Concepción, Análisis Instrumental- Facultad de Farmacia, Concepción, Chile; 2 Universidad Castilla-La Mancha, Instituto Regional de Investigación Científica Aplicada, Ciudad Real, Spain; 3 Universidad de Concepción, Farmacognosia, Concepción, Chile
APP11-P12-We - UHPLC-PDA analysis of oxyprenylated phenylpropanoids in olive, soy, peanuts, corn and sunflower oil using deep eutectic solvent dispersive liquid-liquid micro-extraction techniqueG. Carlucci1, S. Genovese1, F. Epifano1, S. Fiorito1, M. Tiecco2, R. Germani2, M. Carlucci3, V.A. Taddeo1, V. Ferrone1
1 University "G.d'Annunzio", Pharmacy, Chieti, Italy; 2 University of Perugia, Department of Chemistry- Biology and Biotechnology, Perugia, Italy; 3 University "G.d'Annunzio", Department of Medical- Oral and Biotechnological sciences, Chieti, Italy
APP11-P13-We - Routine analysis of ingredients in wineH. Schlicke, K. MonksKNAUER Wissenschaftliche Geräte GmbH, Applications & Academy, Berlin, Germany
APP11-P14-We - Comprehensive profiling of amino acid degradation products by LC-HR-MS/MSS. Neubauer, M. LämmerhoferEberhard Karls Universität Tübingen, Pharmazeutisches Institut, Tübingen, Germany
APP11-P15-We - HPLC separation of derivatized amino acids in meadJ. Klikarová, J. Šebková, L. Česlová, J. FischerUniversity of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic
APP11-P16-We - A novel, highly robust LC-IRMS solution for high-throughput determination of honey adulterationC. Schmidt, F. Volders, M. de Reus, L. Lange, H.P. SieperElementar Analysensysteme GmbH, Product Marketing, Langenselbold, Germany
119HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP11-P17-We - Beer fingerprinting and identification by principal component analysis (PCA) of HPLC data for mono- and oligo- saccharide profilesM. Franc1, I. Prochazkova1, M. Vorsilak2, D. Svozil2, P. Dostalek3, J. Oslovska4, M. Minarik1, M. Minarik1,5
1 Watrex Praha s.r.o., HPLC laboratory, Prague, Czech Republic; 2 University of Chemistry and Technology, Laboratory of Informatics and Chemistry, Prague, Czech Republic; 3 University of Chemistry and Technology, Department of Biotechnology, Prague, Czech Republic; 4 Research Institute of Brewing and Malting- PLC, Prague, Czech Republic; 5 Charles University, Department of Analytical Chemistry- Faculty of Science, Prague, Czech Republic
APP11-P18-We - Molecularly imprinted polymer solid phase extraction coupled with HILIC UHPLC-MS/MS as a new strategy for monitoring aminoglycoside residues in milk samples and functional foodsA.M. Garcia-Campaña1, A. Mohammed Hamed1,2, D. Moreno-González1, L. Gámiz-Gracia1
1 University of Granada, Analytical Chemistry - Faculty of Sciences, Granada, Spain; 2 Cairo University, Dairy Science - Faculty of Agriculture, Giza, Egypt
APP11-P19-We - Analysis of heterocyclic amines in meat by the QuEChERS coupled with liquid chromatography-diode array-tandem mass spectrometryH.Y. Hsiao, B.H. Chen, T.H. KaoFu Jen Catholic University, Food Science, New Taipei City, Taiwan- Province of China
APP11-P20-We - Characterization of phenolic compounds in juices, pulps, peels and seeds of seven Italian pomegranate cultivars by means of RP-HPLC/PDA/MSM. Russo1, G. Tripodo1, C. Vitali1, P. Dugo1,2,3, R. Muleo4, M. Zecchini4, L. Mondello1,2,3, C. Fanali1, L. De Gara1
1 University Campus Bio-Medico of Rome, Unit of Food Science and Nutrition- Department of Medicine, Rome, Italy; 2 University of Messina - Polo Annunziata, Dipartimento di “Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali”, Messina, Italy;
3 Chromaleont, S.r.L., Messina, Italy; 4 University of Tuscia, Dipartimento di “Scienze Agrarie e Forestali”, Viterbo, Italy
APP11-P21-We - Following the fermentation process of beer by HPLCW. Long, A. Mack, J. Link, R. Cook, A. BivensAgilent Technologies, Columns and Supplies, Wilmington, USA
APP11-P22-We - Effect of heat treatment and storage conditions on mead compositionD. Kahoun1, S. Řezková2, J. Královský2
1 University of South Bohemia in Ceske Budejovice, Institute of Chemistry and Biochemistry - Faculty of Science, Ceske Budejovice, Czech Republic; 2 University of Pardubice, Department of Analytical Chemistry - Faculty of Chemical Technology, Pardubice, Czech Republic
APP11-P23-We - Non-invasive profiling of volatiles using headspace-SPME/GC-MS technique and its application for discriminating the geographical origin of white riceD.K. Lee1, D.K. Lim2, C. Mo3, N.P. Long2, J. Lim3, S.W. Kwon1,2
1 Seoul National University, Plant Genomics and Breeding Institute, Seoul, Republic of Korea; 2 Seoul National University, College of Pharmacy, Seoul, Republic of Korea; 3 Rural Development Administration, National Institute of Agricultural Sciences, Jeonju, Republic of Korea
APP11-P24-We - Targeted lipidomics using direct infusion-tandem mass spectrometry reveals distinct lysoglycerophospholipids level of rice (Oryza sativa L.) from different originH.M. Kim1, D.K. Lim1, C. Mo2, P.L. Nguyen1, G. Kim2, S.W. Kwon1
1 Seoul National University, College of Pharmacy, Seoul, Republic of Korea; 2 Rural Development Administration, National Institute of Agricultural Sciences, Jeonju, Republic of Korea
APP11-P25-We - Evaluation of an enzymatic treatment for the selective fractionation of goat milk carbohydrates prior to high performance liquid chromatographic analysisA. Martín1, R. Jimenez1, A.I. Ruiz1, M. Francisco Javier2, M.L. Sanz1
1 Instituto de Química Orgánica General - CSIC, AIQA, Madrid, Spain; 2 Instituto de Investigación en Ciencias de la Alimentación - CSIC, quimica y funcionalidad de carbohidratos, Madrid, Spain
APP11-P26-We - Validation of multi class pesticide multi-residue methods in agricultural commodities by liquid chromatograph coupled with tandem mass spectrometerH.S. Lee, E.H. Choi, H.Z. Lee, H.W. Chung, G.S. RheeMinistry of Food and Drug Safety, Food Safety Evaluation Department- Pesticide and Veterinary Drug Residue Division, Chungcheongbuk-do Cheongju, Republic of Korea
120 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP11-P27-We - Analysis of mycotoxins in cereal and corn without derivatization via LC-MS/MS with time-managed MRMsK. BaudinPerkinElmer, Chromatography, Villebon sur Yvette, France
APP11-P28-We - Hazelnut kernel phenolic compounds extraction optimization and characterization by RP-HPLC/PDA/ESI-MSC. Fanali, G. Tripodo, M. Russo, L. De GaraCampus Bio-Medico University of Rome, Departmental Faculty of Medicine and Surgery, Rome, Italy
APP11-P29-We - Investigation of mycotoxins in beverages such as beer with the Mycotoxin Screening System using several cleanup techniquesC. Schultz1, R. Ludwig1, P. Jochems1, G. Schad2
1 Shimadzu Europa GmbH, Customer Care, Innovation & Product Support, Duisburg, Germany; 2 Shimadzu Europa GmbH, Marketing Europe/ Analytical Business Unit, Duisburg, Germany
APP11-P30-We - Determination of phenolic compounds in cereals using HPLC/MSL. Ceslova, P. Hofmeister, P. ŠilarováUniversity of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic
APP11-P31-We - Charged aerosol detection for LC analysis of triglycerides in extra-virgin olive oilP. Lucci, I.F. Conte, J. PippittDepartment of Agri-Food- Animal and Environmental Sciences University of Udine, Department of Agri-Food- Animal and Environmental Sciences University of Udine, Via Sondrio 2/a- 33100 Udine, Italy
APP11-P32-We - Screening and discrimination of volatile compounds in fermented coffees using head space - solid-phase microextraction-gas chromatography/mass spectrometry (HS-SPME-GC/MS)S.J. Kim1,2, S. Na3, S. Lee2,4, J.H. Lee2,4, J.K. Rhee1, Y.C. Na2,4
1 Ewha Womans University, Food Science and Engineering, Seoul, Republic of Korea; 2 Korea Basic Science Institute, Western Seoul Center, Seoul, Republic of Korea; 3 Sejong Science High School, Science Lab, Seoul, Republic of Korea; 4 Ewha Womans University, Chemistry and Nano Science, Seoul, Republic of Korea
APP11-P33-We - HPLC-MS characterization of bioactive compounds in mentha sp. extracts obtained by microwave assisted extractionM.J. García, D. Mansukhani, A.I. Ruiz-Matute, M.L. Sanz, A.C. SoriaInstituto de Química Orgánica General - CSIC, AIQA, Madrid, Spain
APP11-P34-We - Determination of quaternary ammonium salts and veterinary drugs in foodH. Riering1, N. Helle2, F. Chmelka2, M. Matkovskaia2, J. Bauer2
1 Macherey-Nagel, Innovation Center, Dueren, Germany; 2 TeLA GmbH, Food Analysis, Geestland, Germany
APP11-P35-We - Application of QDa detector for food additives determinationA. Krmela, V. Schulzova, J. Pulkrabova, J. HajslovaUCT Prague, Food analysis and nutriton, Praha - Dejvice, Czech Republic
APP11-P36-We - LC-MS/MS analysis of novel Fusarium mycotoxins in cerealsM. Vaclavikova1, E. Varga1, G. Wiesenberger2, C. Hametner3, K. Twaruschek2, A. Malachova1, G. Adam2, F. Berthiller1
1 University of Natural Resources and Life Sciences - Vienna BOKU, Department of Agrobiotechnology IFA-Tulln, Tulln, Austria;
2 University of Natural Resources and Life Sciences - Vienna BOKU, Department of Applied Genetics and Cell Biology, Tulln, Austria; 3 University of Technology- Vienna, Institute of Applied Synthetic Chemistry, Vienna, Austria
APP11-P37-We - Fast analysis of natural and artificial vanilla flavorings computer assisted development of a robust, fast and sensitive UHPLC methodP. Jochems1, G.J. Schad2
1 Shimadzu Europa GmbH, CIPS, Duisburg, Germany; 2 Shimadzu Europa GmbH, Analytical Business Unit, Duisburg, Germany
121HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP11-P38-We - Simultaneous determination of pantothenic acid and riboflavin in milk by UHPLCA. Schmidt, K. Reiter, H.K. MayerBOKU - University of Natural Resources and Life Sciences Vienna, Department of Food Science and Technology- Food Chemsitry Laboratory, Vienna, Austria
APP11-P39-We - New method based on salting-out assisted liquid-liquid extraction and capillary liquid chromatography to determine benzimidazoles in milk samplesF.J. Lara, C. Tejada-Casado, M. del Olmo-Iruela, A.M. García-Campaña, V. Joyanes Cardenas, M.D. Escolano Gálvez, P. Reche RamírezUniversity of Granada, Analytical Chemistry, Granada, Spain
APP11-P40-We - Mass spectrometry detection and quantification of allergenic proteins in Chilean winesJ. Pavón Pérez1, K. Henriquez-Aedo1, M. Herrero Calleja2, M. Aranda Bustos1
1 Concepcion University, Laboratory of Advanced Research on Foods and Drugs- Department of Food Science and Technology- Faculty of Pharmacy, Concepcion, Chile; 2 Instituto de Investigación de Ciencias de la Alimentación CIAL, Laboratory of Foodomics, Madrid, Spain
APP11-P41-We - Application of experimental design for the optimization of a QuEChERS methodology for the extraction of polyphenols in beerO. Galarce-Bustos1, D. Arráez-Román2, M. Aranda1
1 University of Concepcion, Department of Food Science and Technology, Concepcion, Chile; 2 University of Granada, Department of Analytical Chemistry, Granada, Spain
APP11-P42-We - Robust LC-MS analysis of pesticides with 1.0 mm ID columns using state of the art UHPLC instrumentationR. Bauder1, A. Boychenko2, G. Greco2, M. Martin2, R. Swart2
1 Thermo Fisher Scientific, Product Marketing, Chelmsford, USA; 2 Thermo Fisher Scientific, Chromatography and Mass Spectrometry Division, Germering, Germany
APP11-P43-We - Varietal flavonol profiles of tannat, marselan and syrah vitis vinifera grape skins, wines and marc, determined by an HPLC-MSn systemG. Favre1, G. González-Neves1, D. Piccardo1, S. Gómez-Alonso2, I. Hermosín-Gutiérrez2
1 Facultad de Agronomía Universidad de la República UDELAR Uruguay, Tecnología de los Alimentos - Enología, Montevideo, Uruguay; 2 Universidad de Castilla-La Mancha, Instituto Regional de Investigación Científica Aplicada, Ciudad Real, Spain
APP11-P44-We - DNA extraction from olive oil fruit and its use in the identification of cultivarG. Ramis-Ramos, N. Puertes-Espadas, Ò. Mompó-Rosselló, A. Maurí-Aucejo, E.F. Simó-AlfonsoUniversity of Valencia, Analytical Chemistry, Burjassot, Spain
APP11-P45-We - Development and validation of a large multiresidue LC-MS/MS method using on-line dilution and other useful featuresK. Mastovska1, J. Zulkoski1, E. Deal2, L. Vaclavik3, U. Koesukwiwat4
1 Covance Laboratories, Food Solutions, Madison, USA; 2 Covance Laboratories, Food Solutions, Greenfield, USA; 3 Covance Laboratories, Food Solutions, Harrogate, United Kingdom; 4 Covance Laboratories, Food Solutions, Singapore, Singapore
APP11-P46-We - Sensitive and high throughput determination of deoxynivalenol and its metabolites in human urine by UPLC-MS/MS following µElution SPE cleanupS. Zhou, X. Zhao, Y. Zhao, Y. WuChina National Center for Food Safety Risk Assessment, Chemistry Department, Beijing, China
APP11-P47-We - Characterization and classification of spanish paprika with product designation of origin by HPLC-UV and HPLC-amperometric fringerprintingO. Nuñez1,2, M. Aragó1, A. Gámez1, N. Serrano1, J.M. Díaz1, C. Ariño1, M. Esteban1
1 University of Barcelona, Department of Chemical Engineering and Analytical Chemistry, Barcelona, Spain; 2 University of Barcelona, Research Institute in Nutrition and Food Safety, Santa Coloma de Gramenet, Spain
APP 12 Natural productsAPP12-P01-We - HPLC as a tool to valorize freshwater green macroalgae from PolandJ. Fabrowska, B. ŁęskaAdam Mickiewicz University in Poznań, Faculty of Chemistry, Poznań, Poland
122 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP12-P02-We - Isolation and identification of major antioxidant compounds of Jamaica cherry by HPLC and LC-MassC.T. Lin1, D.J. Yang2, Y.Z. Chang3, Y.C. Chen4, T.Y. Chen1
1 Chung Shan Medical University, Department of Medical Applied Chemistry, Taichung, Taiwan- Province of China; 2 China Medical University, Department of Nutrition, Taichung, Taiwan- Province of China; 3 Chung Shan Medical University, Institute of Medicine, Taichung, Taiwan- Province of China; 4 National Taiwan University, Department of Animal Science and Technology, Taipei, Taiwan- Province of China
APP12-P03-We - HPLC-PDA method for the comparison of the extraction methods efficiency of selected prenylated and unprenylated coumarins and cinnamic acids in dill, anise and wild celeryV.A. Taddeo1, F. Epifano1, S. Fiorito1, V. Ferrone1, M. Carlucci2, G. Carlucci1, S. Genovese1
1 University “G. d’Annunzio” of Chieti-Pescara, Department of Pharmacy, Chieti, Italy; 2 University “G. d’Annunzio” of Chieti-Pescara, Department of Medical- Oral and Biotechnological Sciences, Chieti, Italy
APP12-P04-We - Identification and quantification of lignans in Pinus radiata industry forest waste and its comparison through three extractive techniquesC. Vergara, J.P. Inostroza, J. TroncosoUniversidad de Concepción, Análisis Instrumental- Facultad de Farmacia, Concepción, Chile
APP12-P05-We - On line characterization of flavonoid glycosides in three anti-dengue active Brazilian Faramea species leaves (Rubiaceae) by HPLC-DAD-ESI-CID-MS/MST. Wolff1, L.A. Berrueta2, L.M.M. Valente1, M. Gomes3, R.S. Barboza1, A.C. Nascimento1, I. Assunção-Miranda4, B. Gallo2
1 Universidade Federal do Rio de Janeiro, Instituto de Química, Rio de Janeiro, Brazil; 2 Universidad del Pais Vasco/Euskal Herriko Unibertsitatea, Facultad de Ciencia y Tecnología, Leioa, Spain; 3 Instituto de Pesquisas Jardim Botânico do Rio de Janeiro, Rio de Janeiro, Brazil; 4 Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Rio de Janeiro, Brazil
APP12-P07-We - RP-HPLC analysis of salicylic acid and related metabolic intermediates in willow bark and dietary supplementsE. Kožuszniková, M. Bittová, P. KubáňMasaryk University, Department of Analytical Chemistry, Brno, Czech Republic
APP12-P08-We - An efficient relative quantification method for ginsenosides in ginseng products by evaporative light scattering detectorG.J. Lee, S.W. Kwon, J.H. ParkCollege of Pharmacy, Seoul National University, Seoul, Republic of Korea
APP12-P09-We - Development of RP-HPLC for the separation and determination of D-mandelonitrile-β-D genciobiozid epimers in food supplementsI. Boháčová, R. HalkoFaculty of Natural Sciences- Comenius University in Bratislava, Department of Analytical Chemistry, Bratislava, Slovakia
APP12-P10-We - A new challenge - development of a purification method for industrially extracted Mimosa tanninA. Oberle, G. Tondi, T. Schnabel, A. PetutschniggSalzburg University of Applied Sciences, Forest Products Technology & Timber Construction Department, Kuchl, Austria
APP12-P11-We - Analytical approache for the identification of new ligands of peroxisome proliferator-activated receptors (PPARs) from plant extractG. Massolini, G. Brusotti, E. Calleri, C. TemporiniUniversity of Pavia, Drug Sciences, Pavia, Italy
APP12-P12-We - A validated HPLC method for separation and simultaneous determination of thirteen flavonoids and other polyphenolsD. Pecher1,2, S. Dokupilová1,2, P. Mikuš1,2
1 Faculty of Pharmacy- Comenius University in Bratislava, Department of Pharmaceutical Analysis and Nuclear Pharmacy, Bratislava, Slovakia; 2 Faculty of Pharmacy- Comenius University in Bratislava, Toxicological and Antidoping center, Bratislava, Slovakia
123HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP12-P13-We - Determination of testosterone and corticosterone in feathers of barn swallows (Hirudo Rustica)Z. Bílková1, M. Kotasová Adámková2,3, O. Tomášek3,4, T. Albrecht3,4, Z. Šimek1
1 Research Centre for Toxic Compounds in the Environment, Masaryk University, Brno, Czech Republic; 2 Department of Botany and Zoology, Masaryk University, Brno, Czech Republic; 3 Institute of Vertebrate Biology, Academy of Sciences, Studenec, Czech Republic; 4 Department of Zoology, Charles University, Prague, Czech Republic
APP12-P14-We - Secrets of dyeing fabrics: Blue dyeM. Ganeczko1, K. Rogala1, B. Witkowski1, M. Biesaga1, M. Grzybowski2, M. Woźniak3, T. Gierczak1
1 University of Warsaw, Faculty of Chemistry, Warsaw, Poland; 2 University of Warsaw, Faculty of Biology, Warsaw, Poland;
3 Polish Academy of Sciences, Institute of Mediterranean and Oriental Cultures, Warsaw, Poland
APP12-P15-We - Optimization of the chromatographic analysis of dietary polyphenols obtained by µSPEed extraction of different food matricesP. Porto-Figueira1, J. Figueira1, J. Pereira1, J. Câmara1,2
1 CQM - Centro de Química da Madeira- Universidade da Madeira, ACE lab - Analytical Chemistry and Enology lab, Funchal, Portugal; 2 Universidade da Madeira, Faculdade de Ciências Exatas e da Engenharia, Funchal, Portugal
APP 13 Clinical analysisAPP13-P02-We - Monitoring of cefepime in human serum and plasma by micellar electrokinetic capillary chromatography and liquid chromatography coupled to mass spectrometryN. Šestáková, R. Theurillat, P. Sendi, W. ThormannUniversity of Bern, Bern, Switzerland
APP13-P03-We - New LC-MS/MS method for determination of plasma bisphenols, parabens and estrogens revealed three times higher levels of bisphenol F than bisphenol A in healthy menL. Kolatorova1, T. Chlupacova1, J. Vitku1, J. Heracek2, M. Vlk3, L. Starka1, R. Hampl11 Institute of Endocrinology, Department of Steroids and Proteofactors, Prague, Czech Republic; 2 Charles University in Prague - First Faculty of Medicine, Department of Urology, Prague, Czech Republic; 3 Institute of Experimental Botany ASCR, Isotope Laboratory, Prague, Czech Republic
APP13-P04-We - Newly developed LC-MS/MS method for determination of 7β-hydroxy-epiandrosterone revealed its higher concentrations in infertile menJ. Vitku1, L. Kolatorova1, T. Chlupacova1, J. Heracek2, R. Hampl1, L. Starka1
1 Institute of Endocrinology, Department of Steroids and Proteofactors, Prague, Czech Republic; 2 Charles University in Prague - First faculty of Medicine, Department of Urology, Prague, Czech Republic
APP13-P05-We - Chromatographic analysis of thiamine and its derivatives for routine diagnostics in whole bloodJ. Jenčo1,2, L. Kujovská Krčmová1,2, L. Javorská1,2, K. Čentíková1, D. Solichová1,2, P. Solich1
1 Charles University- Faculty of Pharmacy in Hradec Králové, Department of Analytical Chemistry, Hradec Králové, Czech Republic; 2 University Hospital, 3rd Internal Gerontometabolic Clinic, Hradec Králové, Czech Republic
APP13-P06-We - Analysis of genetic variants of transferrin in human serum after desialylation by capillary zone electrophoresis and capillary isoelectric focusingJ. Caslavska1, C. Lanz1, P. Burda2, M. Tobler2, W. Thormann1
1 University of Bern, Clinical Pharmacology Laboratory- Institute for Infectious Diseases, Bern, Switzerland; 2 University Children's Hospital Zürich, Division of Metabolism, Zürich, Switzerland
APP13-P07-We - New UHPLC-MS/MS method for determination of urinary retinol in patients with various diseasesK. Kučerová1,2, L. Kujovská Krčmová1,2, Z. Mikanová1, L. Matysová1
1 Charles University- Faculty of Pharmacy in Hradec Králové, Department of Analytical Chemistry, Hradec Králové, Czech Republic; 2 University Hospital in Hradec Králové, 3rd Internal Gerontometabolic Clinic, Hradec Králové, Czech Republic
APP13-P08-We - Development and application of an enzyme activity assay for β-hydroxybutyrate dehydrogenase using LC-MS and stable isotope labelingE.M. Prugger1, A. Eberl1, M.M. Schober2, D.A. Merle2, P. Kotzbeck2, C. Magnes1, F. Sinner1
1 Joanneum Research, HEALTH-Institute for Biomedicine and Health Sciences, Graz, Austria; 2 Medical University of Graz, Department of Internal Medicine, Graz, Austria
124 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP13-P09-We - A new tool for the automated sample preparation of whole blood samples by LC-MS using a commercial autosamplerG. Boehm1, C. Berchtold2, R. Bolliger1, R. Falsia1, T. Preiswerk1, G. Schlotterbeck2
1 CTC Analytics AG, Applications, Zwingen, Switzerland; 2 Fachhochschule Nordwestschweiz, Hochschule für Life Sciences, Muttenz, Switzerland
APP13-P10-We - Comparative quantification of inflammation proteins in dried blood samples and serum using selected reaction monitoring mass spectrometry and immunonephelometryV. Vidova1, M. Klugova1,2, V. Thon1,2, J. Klanova1, Z. Spacil11 Masaryk University- Faculty of Science, Research Center for Toxic Compounds in the Environment RECETOX, Brno, Czech Republic; 2 St. Anne’s University Hospital Brno, Department of Immunology, Brno, Czech Republic
APP13-P11-We - The optimal separation of very polar small molecules using UHPLC–MS/MS: Comparison of various stationary phases and its possible application for clinical researchL. Javorska1,2, L. Kujovska Krcmova1,2, N. Hazukova1, J. Jenco1,2, L. Sobotka2, P. Solich1
1 Charles University, Faculty of Pharmacy in Hradec Králové, Hradec Králové, Czech Republic; 2 University Hospital Hradec Králové, 3rd Internal Gerontometabolic Clinic, Hradec Králové, Czech Republic
APP13-P12-We - Metabolic signatures of adrenal steroids from saliva and serum using LC-MS/MS with the polarity switchingN. Lee, M.H. ChoiKIST, Molecular Recognition Research Center, Seoul, Republic of Korea
APP13-P13-We - Simultaneous determination of gemcitabine hydrochloride and irinotecan hydrochloride in rat plasma by high performance liquid chromatography-diode array detectorD. Cosco1, M. Locatelli2, C. Celia2, D. Paolino3, L. Di Marzio2
1 University of Catanzaro “Magna Græcia”-, Inter-Regional Research Center for Food Safety & Health, Catanzaro, Italy;
2 University "G. D'Annunzio" of Chieti-Pescara, Dept. Of Pharmacy, Chieti, Italy; 3 University of Catanzaro ‘‘Magna Graecia’’, Department of Clinical and Experimental Medicine, Catanzaro, Italy
APP13-P14-We - The analysis of C3-epimers of 25-hydroxyvitamin D in serum by LC/MS/MST. Kahler, S.H. Liang, S. Lupo, F. CarrollRestek Corporation, LC Solutions, Bellefonte, USA
APP13-P15-We - Individual variations in urinary caffeine levels and coffee response among middle age womenM. YangSookmyung Women's University, Reasearch Center for Cell Fate Control- College of Pharmacy, Seoul, Republic of Korea
APP13-P16-We - Identifying vitamins D2/D3 and their 25-OH metabolites and C3 epimers in a single LC-MS runK. Tseng1, T. Ono2, T. Hirose3, D. Keck4
1 Nacalai USA- Inc., Product Manager, San Diego, USA; 2 Nacalai USA- Inc., Vice President, San Diego, USA; 3 Nacalai Tesque- Inc., Research and Development, Kyoto, Japan; 4 Nacalai Tesque- Inc., International Business Development, Kyoto, Japan
APP13-P17-We - Development of a simplified HPLC method for multiresidual determination of carbamate and organophosphorus in blood and liver of companion animalsB.H. de Souza1, L.S. Watanabe2, T.B. Madeira2, V.A.D.S. Weigert1, M.B. Almeida2, E. Carrilho3, A.L. Chryssafidis1, S.L. Nixdorf2
1 Laboratório de Toxicologia Veterinária- Universidade Estadual de Londrina, ToxiVet- CCA-DMVP, Londrina, Brazil; 2 Laboratório de Desenvolvimento de Instrumentação e Automação Analítica – DIA- Universidade Estadual de Londrina, Chemistry, Londrina, Brazil; 3 Instituto de Química de São Carlos – BioMics- Universidade de São Paulo, Chemistry, Sao Carlos, Brazil
125HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP 14 ENVIRONMENTAL ANALYSISAPP14-P01-We - Rapid screening of parabens in human urine samples by ultrasound-assisted liquid-liquid microextraction and isotope dilution UHPLC-QTOF-MSW.H. Ding, J.L. WangNational Central University, Department of Chemistry, Taoyuan, Taiwan- Province of China
APP14-P02-We - Determination of perfluoroalkyl acid isomers in soils, plants and earthworms collected from biosolids-amended fields using UPLC-MS/MSB. Wen, H. Zhang, Y. Wu, S. ZhangState Key Laboratory of Environmental Chemistry and Ecotoxicology- Research Center for Eco-Environmental Sciences- Chinese Academy of Sciences, Beijing, China
APP14-P04-We - Degradation products of sulfamethoxazole after treatment with chlorine dioxideK. Eckey1, S. Willach2, H.V. Lutze2, T.C. Schmidt2, U. Karst1
1 University of Muenster, Institute of Inorganic and Analytical Chemistry, Muenster, Germany; 2 University Duisburg-Essen, Faculty of Chemistry- Instrumental Analytical Chemistry, Essen, Germany
APP14-P06-We - Sensitive online SPE determination of bisphenol A in water samplesJ. Böttcher, K. Monks, J. RohloffKNAUER Wissenschaftliche Geräte GmbH, Applications & Academy, Berlin, Germany
APP14-P07-We - On-line miniaturized solid phase extraction (mSPE) for organic pollutant determination at seawater samplesD. Vega-Moreno1, B. Abaroa-Pérez1, J.J. Hernández-Brito2
1 Universidad de Las Palmas GC ULPGC, Chemistry, Las Palmas de G.C., Spain; 2 Plataforma Oceánica de Canarias PLOCAN, Telde, Spain
APP14-P09-We - Ionic liquid modified metal-organic framework composite as dSPE material and LC-MS/MS for determination of glyphosate, bialaphos and thier metabolins in environmental waterM. JinNingbo Municipal Center for Disease Control and Prevention- Ningbo- Zhejiang- 31, Zhejiang Provincial Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals, Ningbo, China
APP14-P10-We - Determination of the degree of substitution of hydrophobized hyaluronan by gas chromatographyJ. Kulhanek, M. Hermannova, R. Sulakova, G. Huerta-Angeles, D. Smejkalova, V. VelebnyContipro a.s., Dolni Dobrouc, Czech Republic
APP14-P11-We - The study of 17β-estradiol and 17α-ethynylestradiol sorption behavior in water-sediment system using QuEChERSJ. Sadílek1, M. Hvězdová1, B. Maršálek2, Z. Šimek1
1 Masaryk university, RECETOX, Brno, Czech Republic; 2 Institute of Botany AS CR, Department of experimental phycology and ecotoxicology, Brno, Czech Republic
APP14-P12-We - Optimization and validation of a UPLC -MS/MS using Unispray for the quantification of pesticide metabolites in surface, ground and drinking watersK. Van Den Steen, P. JoosWater-link, Laboratory, Antwerp, Belgium
APP14-P13-We - Screening methodology for the determination of unknowns in drinking, surface and waste watersP. Joos, E. Van Meenen, K. Van Den SteenWater-link, Laboratory, Antwerp, Belgium
APP14-P14-We - Comparison of different interfaces in LC-MS/MS in the determination of glyphosate and AMPAJ. Daems, K. Van Den Steen, P. JoosWater-link, Laboratory, Antwerp, Belgium
126 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP14-P15-We - Development and validation of a hydrophilic interaction LC-MS/MS method for the quantification of the antidiabetic drug metformin and six others pharmaceuticals in wastewaterR. Oertel1, J. Baldauf2, J. Rossmann2
1 GWT TU Dresden, Institute of Clinical Paharmacology, Dresden, Germany; 2 TU Dresden, Institute of Clinical Pharmacology, Dresden, Germany
APP14-P16-We - Screening of soil and fish contamination with dechlorane-related flame retardants in Guiyu: The largest E-waste recycling city in ChinaW. Tao1, L. Shen2, L. Xu1, Z. Zhou1, H.Q. Xie1, B. Zhao1
1 State key laboratory of environmental chemistry and ecotoxicology- Research Center for Eco-Environmental Sciences- Chinese Academy of Sciences, Beijing, China; 2 Ontario Ministry of the Environment and Climate Change, Toronto- Ontario, Canada
APP14-P17-We - UHPLC optimization for food and beverage additive analysisA. Lamb1, K. Meadows1, B. King1, M. DePra2, S. Fabel2, J. Bardsley1
1 Thermo Fisher Scientific, Chromatography and Mass Spectrometry, Runcorn, United Kingdom; 2 Thermo Fisher Scientific, Chromatography and Mass Spectrometry, Germering, Germany
APP14-P18-We - Determination of amino acids in ensiled grass press juice using LC-MS/MSP. Fojtíková1, D. Kahoun1, D. Schwarz2
1 Faculty of Science- University of South Bohemia, Department of Chemistry and Biochemistry, České Budějovice, Czech Republic; 2 Technical University of Munich, Chair of Chemistry of Biogenic Resources, Straubing, Germany
APP14-P19-We - Quantitation of pharmaceutical and personal care products in water using a laminar flow tandem mass spectrometerA. Bisi1, S. Reddy2, K. Baudin3, J. Foss2
1 PerkinElmer Italia SpA, Sales, Milan, Italy; 2 PerkinElmer Inc., Research and developement, Shelton, USA; 3 PerkinElmer Inc., Europe team, Villebon sur Yvette, France
APP14-P20-We - Optimization of sample preparation techniques for isolation of cyanopeptides (anabaenopeptin, microginins) from cyanobacterial biomass sampled in the Czech RepublicL. Jaša1, P. Urajová2, P. Hrouzek2, K. Hilscherová1, L. Švihálková Šindlerová3, P. Babica1
1 Masaryk university, Recetox, Brno, Czech Republic; 2 Institute of Microbiology of the Czech Academy of Sciences, Centre Algatech, Třeboň, Czech Republic; 3 Institute of Biophysics of the Czech Academy of Sciences, Department of Free Radical Pathophysiology, Brno, Czech Republic
APP14-P21-We - Capillary gel electrophoretic analysis for the degradation study of nanodispersed zein as pesticide delivery systemT. Kacsó1, I.O. Neaga1, A. Erincz1, C.E. Astete2, C.M. Sabliov2, R. Oprean1, E. Bodoki11 Iuliu Hatieganu University of Medicine and Pharmacy, Analytical Chemistry and Instrumental Analysis, Cluj-Napoca, Romania;
2 Louisiana State University, Biological & Agricultural Engineering, Baton Rouge, USA
APP14-P23-We - Multiresidues pesticides search and determination in Sassandra RiverN.C. Amin1,2, N.C. Ablé3, K.S. Dibi4, G.S. Degny1, K.A. Malan2,5, L. Kouadio5,6
1 Institut National D'hygiene Publique, Laboratoire des Eaux Et Aliments, Abidjan, Côte D'ivoire; 2 Université Félix Houphouët-Boigny, Chimie Analytique- Bromatologie- Chimie Générale- Chimie Minérale, Abidjan, Côte D'ivoire; 3 Laboratoire National de la Sante Publique, Chimie, Abidjan, Côte D'ivoire; 4 Laboratoire National de la Sante Publique, Toxicologie, Abidjan, Côte D'ivoire; 5 Laboratoire National de la Sante Publique, Direction, Abidjan, Côte D'ivoire; 6 Université Félix Houphouët-Boigny, Santé Publique, Abidjan, Côte D'ivoire
APP14-P24-We - Determination of red clover-derived isoflavones in the rumen fluid by HPLC-DAD/FLDM. Zapletalová, A. Smejkalová, J. Kašparovská, T. KašparovkýMasaryk University, Department of Biochemistry, Brno, Czech Republic
APP14-P25-We - Method development for the analysis of basic pharmaceuticals in wastewaters using SPE and HILIC-MS/MSP. Landová1, M. Kočnar2, M. Vávrová1
1 Brno University of Technology- Faculty of Chemistry, Institute of Environmental Chemistry, Brno, Czech Republic; 2 Brno University of Technology- Faculty of Chemistry, Institute of Physical and Applied Chemistry, Brno, Czech Republic
127HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
APP14-P26-We - Analysis of PAH adsorpted over marine microplastics surface by HPLC with fluorescence detectionD. Vega-Moreno1, B. Abaroa-Pérez1, N. Beltrán-Escuriola2, J.J. Hernández-Brito2
1 Universidad de Las Palmas GC ULPGC, Chemistry, Las Palmas de G.C., Spain; 2 Plataforma Oceánica de Canarias PLOCAN, Telde, Spain
APP14-P27-We - Removal of pharmaceuticals by advanced oxidation processesT. Švestková1,2, P. Landová1,2, T. Macsek2, M. Úterský2, M. Vávrová1, P. Hlavínek2
1 Brno University of Technology, Faculty of chemistry- Institute of Environmental Chemistry, Brno, Czech Republic; 2 Brno University of Technology, Faculty of Civil Engineering- AdMaS centre, Brno, Czech Republic
Program track Young and Tutorials (YOU)YOU 1 2D-LCYOU1-P01-Mo - Chip-based HPLC with an integrated droplet interface for surface enhanced raman detectionR. Gerhardt, A.J. Peretzki, D. BelderUniversity of Leipzig, Institute of Analytical Chemistry, Leipzig, Germany
YOU1-P02-Mo - Membrane evaporative interface for LCxLCE. Fornells1, B. Barnett2, M. Bailey3, R.A. Shellie3, E.F. Hilder4, M.C. Breadmore5
1 University of Tasmania, ARC Training Centre for Portable Analytical Separation Technologies - ASTech, Hobart, Australia;
2 Trajan Scientific and Medical, Melbourne, Australia; 3 Trajan Scientific and Medical, ARC Training Centre for Portable Analytical Separation Technologies - ASTech, Melbourne, Australia; 4 University of South Australia Future Industries Institute, ARC Training Centre for Portable Analytical Separation Technologies - ASTech, Adelaide, Australia; 5 University of Tasmania, Australian Centre for Research on Separation Science, Hobart, Australia
YOU1-P03-Mo - Increasing flexibility in two-dimensional liquid chromatography by pulsed elution of the first dimension (Pulsed-elution 2D-LC)N.J. Nielsen1, S.S. Jakobsen1,2, S. Verdier2, A.B. Hansen2, J.H. Christensen1
1 University of Copenhagen, Plant and Environmental Science, Frederiksberg, Denmark; 2 Haldor Topsoe A/S, Kgs. Lyngby, Denmark
YOU1-P04-Mo - Two-dimentional LC for analysis of monoclonal antibody during bioprocess developmentJ.H. Heo, D. Richardson, S. YuMSD, Bioprocess Development, Kenilworth- NJ, USA
YOU 2 Separation mechanismsYOU2-P01-Mo - Numerical study of the thermal conductivity of columns packed with fully porous and superficially porous particlesS. Deridder, K. Broeckhoven, G. DesmetVrije Universiteit Brussel, Department of Chemical Engineering, Brussels, Belgium
YOU2-P02-Mo - Dual retention mechanism on stationary phases with embedded polar groupK. Krzemińska, S. Bocian, B. BuszewskiNicolaus Copernicus University, Chair of Environmental Chemistry & Bioanalitics, Torun, Poland
YOU2-P03-Mo - Transport of molecules of different sizes through monolithic, core-shell and porous silica columns. Effect of porous silica architectureK.L. Nguyen1,2, V. Wernert1, R. Denoyel1, A. Galarneau3, Y. Didi31 MADIREL, Aix-Marseille University, Marseille, France; 2 Hanoi University of Mining and Geology, Hanoi, Viet Nam; 3 Institut Charles Gerhardt Montpellier, Montpellier, France
YOU2-P04-Mo - Solvation processes in liquid chromatography - the importance and measurementS. Bocian, M. Skoczylas, K. Krzemińska, B. BuszewskiNicolaus Copernicus University in Toruń, Chair of Environmental Chemistry and Bioanalytics, Toruń, Poland
128 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU 3 ProteomicsYOU3-P01-Mo - Characterization of a poly(dimethylsiloxane) microfluidic chip containing immobilized trypsin for rapid protein digestionA. Kecskemeti, C.N. Nagy, A. GasparUniversity of Debrecen, Department of Inorganic and Analytical Chemistry, Debrecen, Hungary
YOU3-P02-Mo - Novel approach to determine lipidated analogs of prolactin-releasing peptide via LC-MS using monolithic columnJ. Zemenová1,2, D. Sýkora2, L. Maletínská1
1 Institute of Organic Chemistry and Biochemistry Czech Academy of Sciences, Group of Lenka Maletínská, Prague, Czech Republic; 2 University of Chemisty and Technology Prague, Department of Analytical Chemistry, Prague, Czech Republic
YOU3-P03-Mo- Trinity P1 mixed mode chromatography enables mass spectrometry compatible orthogonal peptide separation to reversed phaseP. Yu1, M. Wilhelm1, D. Zolg1, X. Sun2, X. Liu2, A. Huhmer3, B. Kuster1
1 Technische Universität München, Freising, Germany; 2 Thermo Fisher Scientific, Sunnyvale, USA; 3 Thermo Fisher Scientific, San Jose, USA
YOU3-P04-Mo - Predictive chromatography of peptides for optimized fractionation in bottom-up proteomicsE. Solovyeva1, A. Lobas2, A. Kopylov3, L. Levitsky2, I. Ilyina3, S. Moshkovskii3, M. Gorshkov2
1 Moscow Institute of Physics and Technology, Department of Molecular and Chemical Physics, Dolgoprudny, Russian Federation; 2 Institute for Energy Problems of Chemical Physics, Moscow, Russian Federation; 3 Institute of Biomedical Chemistry, Moscow, Russian Federation
YOU 4 Sample preparationYOU4-P01-Mo - Determination of selected fat soluble vitamins from bovine milk using dispersive liquid-liquid microextraction coupled with HPLC-UV equipped with a core-shell columnA. Quigley, S. Walsh, D. Connolly, W. CumminsWaterford Institute of Technology, Department of Science, Waterford, Ireland
YOU4-P02-Mo - Development of an HPLC bioreactor based on immobilized enterokinase for the cleavage of fusion proteinsS. Tengattini1, F. Rinaldi1, C. Temporini1, E. Calleri1, L. Piubelli2, T. Bavaro1, G. Massolini11 University of Pavia, Department of Drug Sciences, Pavia, Italy; 2 University of Insubria, Department of Biotechnology and Life Sciences, Varese, Italy
YOU4-P03-Mo - Automated robotic sample preparation for metabolomics with hyphenation to LC-SWATH/MS acquisition for plasma and liver samplesM. Raetz1, R. Picenoni2, G. Boehm2, G. Hopfgartner1
1 University of Geneva, CHIAM, Geneve 4, Switzerland; 2 CTC Analytics, Zwingen, Switzerland
YOU4-P04-Mo - Easy and cheap apparatus for the off-line automatization of miniaturized sample preparation techniquesD.A. Vargas Medina, L. Schwerz, D. Menini, A.J. Santos NetoUniversidade de São Paulo, Instituto de Química de São carlos, São Carlos, Brazil
YOU 5 Metabolomics and lipidomicsYOU5-P01-Mo - Use of a novel linear retention index system as identification tool in liquid chromatography: Applications in lipidomicsF. Rigano1, P. Dugo1,2, L. Mondello1,2
1 Chromaleont S.r.L., c/o Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy; 2 University of Messina, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy
YOU5-P02-Mo - Simultaneous non-polar and polar lipid analysis by complementary online two-dimensional liquid chromatography and high resolution mass spectrometryE. Rampler, B. Mitic, M. Schwaiger, G. KoellenspergerUniversity of Vienna, Analytical Chemistry, Vienna, Austria
129HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU5-P03-Mo - Oxysterols in cancerH. Roberg-Larsen, F. Sved Skottvol, K. Bjørseth, S. Solheim, E. Lundanes, J. Thorne2, S. Ray WilsonUniversity of Oslo, Chemistry, Oslo, Norway; 2 University of Leeds, School of Food Science, Leeds, United Kingdom
YOU5-P04-Mo - Increasing peak capacity and selectivity of LC-MS by incorporation of low-field drift-tube ion mobility separationT. Causon, S. HannUniversity of Natural Resources and Life Sciences BOKU Vienna, Department of Chemistry, Vienna, Austria
YOU 6 Chiral and achiral stationary phasesYOU6-P01-Mo - Stationary phase optimized selectivity chiral liquid chromatography (SOS-CLC) as a novel perspective for the separation of stereoisomersR. Hegade, F. LynenGhent University- Belgium, Separation Science Group- Department of Organic & Macromolecular chemistry- Faculty of Sciences- Ghent University, Ghent, Belgium
YOU6-P02-Mo - Flavanones enantioseparation by LC-ESI-MS/MS and its applicationI. Baranowska, J. Hejniak, S. BajkaczSilesian University of Technology- Faculty of Chemistry, Department of Inorganic- Analytical Chemistry and Electrochemistry, Gliwice, Poland
YOU6-P03-Mo - Multi-parametric characterization of amino acids- and peptide-silica stationary phases – a column selection for separation targetsM. Skoczylas, S. Bocian, B. BuszewskiNicolaus Copernicus University, Toruń, Poland
YOU6-P04-Mo - Nitrogen-incorporated tetrahedral amorphous carbon thin-films - a new electrode for the HPLC-EC of biological and environmental analytesR. Jarosova1,2, A. Castiaux1, J. Qiu3, G. Swain1
1 Michigan State University, Chemistry, East Lansing, USA; 2 Charles University in Prague, University Research Centre UNCE "Supramolecular Chemistry"- Department of Analytical Chemistry- UNESCO Laboratory of Environmental Electrochemistry-, Prague, Czech Republic; 3 Illinois Mathematics and Science Academy, Illinois, USA
YOU 7 Ultrahigh-resolution mass spectrometryYOU7-P01-Mo - Pharmacokinetics and brain uptake study of novel AMPA receptor antagonist perampanel in Sprague Dawely rats using a validated UHPLC-QTOF-MS methodD. Paul, L. Allakonda, A. Sahu, S. Surendran, P. Johnsi Rani, R.P. Sayali, S. NanjappanNational Institute of Pharmaceutical Education and Research NIPER-Hyderabad, Pharmaceutical Analysis, Hyderabad, India
YOU7-P02-Mo - Analysis of chestnut tannins by reversed phase- and hydrophilic interaction chromatography coupled to ion mobility and high resolution mass spectrometryP. Venter, A. de Villiers, H. PaschUniversity of Stellenbosch, Department of chemistry and polymer science, Stellenbosch, South Africa
YOU7-P03-Mo - Solid phase microextraction and liquid chromatography coupled to high resolution mass spectrometry: A powerful platform for in vivo brain metabolomics studiesN. Reyes Garces1, E. BoyacI1, G.A. Gomez Rios1, B. Bojko1, D. Vuckovic2, C. Hamani3, J. Pawliszyn1
1 University of Waterloo, Chemistry, Waterloo, Canada; 2 Concordia University, Montréal, Canada; 3 University of Toronto, Neurosurgery, Toronto, Canada
YOU7-P04-Mo - Measuring steroid profiles in whale blubber by liquid chromatography tandem mass spectrometryA. Boggs1, T. Schock1, L. Schwacke2, T. Galligan3, J. Morey4, W. McFee4, J. Kucklick1
1 National Institute of Standards and Technology, Charleston, USA; 2 National Marine Mammal Foundation, Chalreston, USA;
3 Medical University of South Carolina, Charleston, USA; 4 National Oceanic and Atmospheric Administration, Charleston, USA
130 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU 8 Electromigration techniquesYOU8-P01-Mo - Optimisation of an electrophoretic approach for the screening and the development of new antithrombotic drugsE. Farcaş1, C. Bouckaert2, A.C. Servais1, J. Crommen1, L. Pochet2, M. Fillet1
1 University of Liège, Department of Pharmacy- Laboratory for the Analysis of Medicines- CIRM, Liège, Belgium; 2 University of Namur, Namur Medicine & Drug Innovation Center NaMEDIC- Narilis, Namur, Belgium
YOU8-P02-Mo - Two-dimensional capillary zone electrophoresis coupled to mass spectrometry for the characterization of monoclonal antibody charge variants on the intact levelK. Jooß1,2, J. Hühner1,3, C. Neusüß1
1 Aalen University of Applied Sciences, Faculty of Chemistry, Aalen, Germany; 2 Helmholtz Zentrum München, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany; 3 University of Tübingen, Institute of Pharmaceutical Science, Tübingen, Germany
YOU8-P03-Mo - Single-isomer cyclodextrin derivatives in chiral capillary electrophoresis: The past, the present and the futureE. Varga, T. Sohajda, L. SzenteCyclolab- Cyclodextrin R&D Ltd., Budapest, Hungary
YOU8-P04-Mo - Capillary electrophoresis-mass spectrometry as a novel technique in analysis of cholesterol and its metabolitesM. GregusDepartment of Chemistry, Masaryk University, Brno, Czech Republic
YOU 9 Monolithic columnsYOU9-P01-Tu - Macroscopic three dimensional carbon nanohorns monolith for (micro)solid-phase extraction of volatile organic compoundsB. Fresco, S. CárdenasUniversity of Córdoba, Analytical Chemistry, Córdoba, Spain
YOU9-P02-Tu - Preparation and analytical application of novel anion-exchangers for ion chromatography with improved selectivity toward organic acidsA. Zatirakha, O. Shchukina, A. Uzhel, A. Gorbovskaya, R. Ogorodnikov, A. Smolenkov, O. ShpigunLomonosov Moscow State University, Chemistry department, Moscow, Russian Federation
YOU9-P03-Tu - Variation of parameters influencing the immobilization of ligands onto epoxy-modified silica monolithsB. Peters1, T. Kupfer1, E. Machtejevas2, G. Jung1, P. Knoell11 Merck, Analytical R&D, Darmstadt, Germany; 2 Merck, Advanced Analytical, Darmstadt, Germany
YOU9-P04-Tu - Development of monolithic capillary column with an integrated electrochemical detector for the determination of dopamine in urineM. Komendová1, R. Metelka1, J. Urban2
1 University of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic; 2 Masaryk University, Department of Chemistry, Brno, Czech Republic
YOU 10 SFC and SFC/MSYOU10-P01-Tu - Online supercritical fluid extraction-supercritical fluid chromatography-mass spectrometry for carotenoids determination in red habanero peppersM. Zoccali1, D. Giuffrida2, P. Dugo1,3,4, L. Mondello1,3,4
1 Chromaleont srl, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy; 2 University of Messina, Dipartimento di Scienze Biomediche- Odontoiatriche e delle Immagini Morfologiche e Funzionali, Messina, Italy;
3 University Campus Bio-Medico of Rome, Unit of Food Science and Nutrition- Department of Medicine, Rome, Italy; 4 University of Messina, Dipartimento di Scienze Chimiche- Biologiche- Farmaceutiche ed Ambientali, Messina, Italy
YOU10-P02-Tu - Development of novel poly(vinylpyridine)-based SFC columns and their applicationsK. Nagai1, S. Shinkura1, T. Shibata1, Y. Yoshimoto2, A. Ohnishi21 DAICEL Corporation, CPI company, Himeji, Japan; 2 DAICEL Corporation, CPI company, Myoko, Japan
131HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU10-P03-Tu - Influence of sample injection solvent on peak shape for the analysis of pharmaceutical compounds in SFCV. Desfontaine1, A. Tarafder2, J. Fairchild2, J. Hill2, J.L. Veuthey1, D. Guillarme1
1 University of Geneva, Analytical Sciences, Genève, Switzerland; 2 Waters Corporation, Research, Milford, USA
YOU10-P04-Tu - UHPSFC/ESI-MS lipidomic analysis of tissues and plasma from kidney cancer patientsM. Khalikova1, M. Lísa1, E. Cífková1, D. Vrána2, B. Melichar2, V. Študent3, M. Holčapek1
1 University of Pardubice, Department of Analytical Chemistry, Pardubice, Czech Republic; 2 Palacký University, Medical School and Teaching Hospital- Department of Oncology, Olomouc, Czech Republic; 3 Palacký University, Faculty of Medicine and Dentistry- Department of Urology, Olomouc, Czech Republic
YOU 11 Pharmaceutical analysisYOU11-P01-Tu - Metabolic study of methylstenbolone in horsesL.S. Choi1, J.K.Y. Wong1, W.H. Kwok1, P. Curl2, T.S.M. Wan1
1 The Hong Kong Jockey Club, Racing Laboratory, Hong Kong, Hong Kong; 2 The Hong Kong Jockey Club, Department of Veterinary Regulation and Biosecurity Policy, Hong Kong, Hong Kong
YOU11-P02-Tu - Analytical quality by design - a methodical approach for the quantitative estimation of teriflunomide from human plasmaA. Ayre, M. Bhavsar, P. ChaudhariDr. L. H. Hiranandani College of Pharmacy, Quality Assurance, Ulhasnagar- Thane, India
YOU11-P03-Tu - Exploring mixed-mode HPLC as an alternative to reversed phase HPLC for impurity profiling of drug candidatesE. Lemasson1, Y. Richer1, S. Bertin2, P. Hennig2, E. Lesellier1, C. West1
1 ICOA, Analytical Chemistry, Orléans, France; 2 Institut de Recherches Servier, Suresnes, France
YOU11-P04-Tu - A normal phase chiral HPLC method for the separation of eight isomers of core + omeN. Joshi1, D. Balaji1, A. Athimoolam2, J. Paulose2, J. Tan3, L. Blue3, J. Tedrow4, F. Bob4
1 Syngene Amgen Research Center- Syngene International Limited, Process Development-Attribute Science, Bangalore, India;
2 Syngene Amgen Research Center- Syngene International Limited, Process Development-Drug Substance, Bangalore, India;
3 Amgen, Attribute Science, Thousands Oak- CA, USA; 4 Amgen, Drug Substance Technologies, Thousands Oak- CA, USA
YOU 13 Ultrahigh-performance liquid chromatographyYOU13-P01-Tu - Exploration by UHPLC-HRMS of the enzymatic phosphorylation of pyrimidine nucleosidesJ. Ferey, D. Da Silva, C. Colas, P. Lafite, V. Roy, L. Agrofoglio, R. Daniellou, B. MaunitICOA, Orléans, France
YOU13-P02-Tu - Retention prediction in reversed phase HPLC using quantitative structure-retention relationships applied to the hydrophobic subtraction modelY. Wen1, P.R. Haddad1, M. Talebi1, R.I.J. Amos1, R. Szucs2, J.W. Dolan3, C.A. Pohl41 Australian Centre for Research on Separation Science, School of Physical Sciences-Chemistry, Hobart, Australia; 2 Pfizer Global Research and Development, Sandwich, United Kingdom; 3 LC Resources, McMinnville OR, USA; 4 Thermo Fisher Scientific, Sunnyvale CA, USA
YOU13-P03-Tu - Artificial neural network in the prediction of gradient retention times for rebaudioside A in liquid chromatographyN. Mert Ozupek1, L. Cavas2
1 Dokuz Eylül University- Graduate School of Natural and Applied Sciences, Department of Biotechnology, IZMIR, Turkey;
2 Dokuz Eylül University, Department of Chemistry, IZMIR, Turkey
YOU13-P04-Tu - Development and validation of an analytical residues method of the Aminopropyldodecylpropanediamine biocide disinfectant in dairy products by LC-MS/MSK. Slimani1, Y. Pirotais1, J.P. Abjean1, P. Maris2, D. Hurtaud-pessel11 Anses, Residues and Contaminants Analysis Unit, Fougères, France; 2 Anses, Fougères, France
132 HPLC 2017 PRAGUE, 18 – 22 JUNE 2017, CZECH REPUBLIC
YOU 14 Clinical analysisYOU14-P01-Tu - Systems for detection of monoamines in tissues beyond brainJ. Nagler1, K.W. Schramm1, P. Pfluger2, S. Sonja2
1 Helmholtz Center Munich, MEX, Oberschleißheim, Germany; 2 Helmholtz Center Munich, IDO, Garching, Germany
YOU14-P02-Tu - Discovery and quantification of metabolic markers attributed to the activity of intestinal microbiotaT. Pavlová1, V. Vidová2, J. Bienertová-Vašků1, J. Klánová2, Z. Spáčil21 Masaryk University, Department of Pathological Physiology, Brno, Czech Republic; 2 Masaryk University, Research Centre for Toxic Compounds in the Environment RECETOX, Brno, Czech Republic
YOU14-P03-Tu - Bioactive compounds of steam-blanched and differently dried onionsL. Priecina1, D. Karklina1, I. Cinkmanis2
1 Latvia University of Agriculture, Department of Food Technology, Jelgava, Latvia; 2 Latvia University of Agriculture, Department of Chemistry, Jelgava, Latvia
YOU14-P04-Tu - Determination of phenolic acids using activated carbon-polymer extraction columnW.L. Liu, Y.C. Kuo, H.Y. HuangChung Yuan Christian University, Chemistry, Taoyuan City, Taiwan- Province of China
pubs.acs.org
PUBLISH YOUR RESEARCHWITH CONFIDENCEACS AUTHOR BENEFITS: Global Exposure • Rapid Publication • Highest Editorial Standards Diverse Open Access Options • No Publication Charges
Submit Your Research to ACS Measurement
Science Journals
Saturday 17 June
Sunday 18 June
Monday 19 June
Tuesday 20 June
Wednesday 21 June
Thursday 22 June
08:30 – 09:00Sessions #1FUN HYP APP YOU
Sessions #5FUN HYP APP YOU
Sessions #9FUN HYP APP YOU
09:00 – 09:30
Short Courses 5 – 8
Clubs A, B, D, E
Sessions #13FUN HYP APP YOU
09:30 – 10:00
10:00 – 10:30 Co� ee Break / Exhibition / Posters
Co� ee Break / Exhibition / Posters
Co� ee Break / Exhibition / Posters
10:30 – 11:00Sessions #2FUN HYP APP YOU
Sessions #6FUN HYP APP YOU
Sessions #10FUN HYP APP YOU
Co� ee Break / Exhibition / Posters
11:00 – 11:30Sessions #14FUN HYP APP YOU
11:30 – 12:00
12:00 – 12:30
Lunch / Exhibition / Posters
Vendor Seminars
Lunch / Exhibition / Posters
Vendor Seminars
Lunch / Exhibition / Posters
Vendor Seminars
12:30 – 13:00
Lunch Break13:00 – 13:30
13:30 – 14:00
Closing Plenary Session
14:00 – 14:30
Short Courses 1 – 4
Clubs A, B, D, E
Sessions #3FUN HYP APP YOU
Sessions #7FUN HYP APP YOU
Sessions #11FUN HYP APP YOU
14:30 – 15:00
15:00 – 15:30Opening
Ceremony15:30 – 16:00Co� ee Break /
Exhibition / PostersCo� ee Break /
Exhibition / PostersCo� ee Break /
Exhibition / Posters16:00 – 16:30
Opening Plenary Session
Farewell Drink16:30 – 17:00
Sessions #4FUN HYP APP YOU
Sessions #8FUN HYP APP YOU
Sessions #12FUN HYP APP YOU
17:00 – 17:30
17:30 – 18:00
18:00 – 18:30
Czech Beer Party18:30 – 19:00
19:00 – 19:30
Welcome MixerSymposium Gala
DinnerŽofín Palace
19:30 – 20:00
20:00 – 20:30Organ Concert in Cathedral20:30 – 21:00
PROGRAM AT A GLANCE
HPL
C 2
017
PRA
GU
E –
FIN
AL
PRO
GR
AM
