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Setting the Stage – PAH Therapy Trials. Current PAH Pharmacotherapies. History of LHF Therapy. Disease Modification in LHF. HFrEF Lessons Learned – Moving Forward in PAH. RV Structure and Function in PH – The Downward Spiral. Growth and Immune Response Dysregulation in PAH. - PowerPoint PPT Presentation
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Setting the Stage – PAH Therapy Trials
Current PAH Pharmacotherapies
History of LHF Therapy
Disease Modification in LHF
HFrEF Lessons Learned – Moving Forward in PAH
RV Structure and Function in PH – The Downward Spiral
Growth and Immune Response Dysregulation in PAH
RV Function in PAH
Lessons From HFpEFRV-PA and RV-LV Interactions
Right Heart and Survival in PAH – REVEAL Registry Data
RV-PA and RV-LV Interactions
Evolution of End Point-Driven Trials in PAH
Current and Future Challenges in End Point Design
Right Heart vs Left Heart Therapies
Designing PAH Trials – The Next Steps
Combination Therapy in PAH
Combination Therapy in PAH (cont)
Conclusion
Abbreviations
Abbreviations (cont)
References
References (cont)
References (cont)
References (cont)