SeminárioSeminárioCombustíveis Alternativos

A i ãCombustíveis Alternativos

A i ãpara a Aviaçãopara a Aviação

29 e 30 de novembro de 2011 

Realização Apoio

AmyrisyThe Renewable Carbon

Company™p y

[ 1 ]

OverviewOverview

► Amyris is an integrated renewable products company producing advanced renewable fuels and chemicals:

– Proprietary technology already delivered first commercial-scale success– Use existing sugar/ethanol mills for large volume productionUse existing sugar/ethanol mills for large volume production– Commercial scale renewable products in April 2011

► Founded in 2003 on principle of social responsibility: use our know-how to address p p p ybiggest health and environmental challenges

► World’s leading investors: Kleiner Perkins, Khosla Ventures, TPG

[ 2 ]

Our vision: to enable a bio-based economy

Traditional oil sourceWid f d t

Jet fuel 2020 est: 124 billion gallons + = Petroleum products

Wide range of products

Bio-derived productsOil Diesel2020 est: 450 billion gallons

Refinery

roce

ssin

g

Fermentation using Amyris’ engineered yeastChemicals: e.g. polymers, lubes and

Hyd

ro-p

r

+ Hydrocarbon

Bio-Oils Anti-malaria drug non-profit: treat over 200 million

=surfactants

Amyris genetically engineered yeast

non profit: treat over 200 million people annually

Biomass Sugars

[ 3 ]

Enabling TechnologyFrom sugars to hydrocarbons!

A t i i i A idArtemisinic Acid

H

HHO Anti-Malarial DrugAnti-Malarial Drug

SUGAR SOURCE

YEAST CELL

O

HO

p450

Anti-Malarial DrugAnti-Malarial DrugSugar SyrupSugar Syrup

Isoprenoid PathwayIsoprenoid Pathway

YEAST CELLCPR

ADSDiesel & Chemical Diesel & Chemical PrecursorPrecursorFarnesene Synthase

Farnesene

GPPS

PSISX PSIS

[ 4 ]

Jet / Gasoline PrecursorsJet / Gasoline PrecursorsIsopreneIsopreneEthanolEthanol

Amyris breakthrough technology

Amyris engineered microbes can convert sugar to Bio-OilsAmyris engineered microbes can convert sugar to Bio-Oils

Phase-contrast micrographPhase contrast micrograph of Amyris engineered microbes producing precursor to Amyris R bl Di lRenewable Diesel

Mi b ( t)

Bio-oil

Microbe (yeast)

[ 5 ]

Amyris No CompromiseTM fuels

C d i di f d t kC d i di f d t kCan produce using diverse sugar feedstocks

Hydrocarbons, not alcohols or esters

– Can be used in existing engines with no

Can produce using diverse sugar feedstocks

Hydrocarbons, not alcohols or esters

– Can be used in existing engines with noCan be used in existing engines with no performance trade-offs

– Can be blended up to 50%

Can be delivered using existing distribution

Can be used in existing engines with no performance trade-offs

– Can be blended up to 50%

Can be delivered using existing distribution– Can be delivered using existing distribution infrastructure

Price competitive with petroleum

– Can be delivered using existing distribution infrastructure

Price competitive with petroleum

Superior properties– 80%+ lower greenhouse gas emissions than

petroleumNo sulfur

Superior properties– 80%+ lower greenhouse gas emissions than

petroleumNo sulfur– No sulfur

– Lower particulates and NOx– Excellent cold flow characteristics and energy

density

– No sulfur– Lower particulates and NOx– Excellent cold flow characteristics and energy

densityAmyris diesel fuel (clear) in front; petroleum diesel (yellow) in the back

[ 6 ]

Leverage existing mills for quick scale

DehydrationNot required since FinishingNot required since hydrocarbons separate easily from water

FinishingChemical step required to convert intermediate to final product requires hydrogen as raw material

Fermentation Recovery Distillation DehydrationCane

Processing/Electricity Generation

Hydro-processing

PurificationEnergy intensive distillation process not required. Recovered energy may be utilized in the plant

Simple production process using current mill infrastructure

[ 7 ]

Manufacturing timeline for first product

20092009 20102010 20112011 2012 - 20132012 - 2013

Convert Brazil ethanol mills to produce Amyris

First large scale production of Amyris

First commercial production by third

Brazil R&D center inaugurated in mills to produce Amyris

renewable products• Basic engineering of

commercial plant has been finalized and EPCM

production of Amyris renewable products

Continue mill conversion and

production by third party mills

inaugurated in Campinas

Brazil and US Pilot plant operational

CH2MHill has been engaged

Commercialize first product out of demo

expansionBrazil Demo Facility opened

Secure production in product out of demo facility

Secure production in Brazil

• Owned/controlled• Third parties

[ 8 ]

Opportunities from technology platform

Our microbial platform allows us to access over 50,000 isoprenoid molecules biologically. By adding chemistry post bio-production, we can produce multiple products per molecule.

Sugar

By adding chemistry post bio production, we can produce multiple products per molecule.

Amyrisbiological pathway

• Unlike chemical processing, a complex series of reactions can occur in a single cell

biology

chemistry

C-5 l l

C-10 l l

C-15 l l

occur in a single cell

• Initial focus on the following products- C-15: farnesene,

molecules molecules molecules

isoprene Farnesene/BiofeneTMC10 molecules

renewable diesel- C-5: isoprene- C-10: jet fuel

renewable diesel

“C30 molecules” (multiple app’s)

poly-farnesene (polymer)

poly-isoprene (polymer)

jet fuel

[ 9 ]

Amyris Jet Fuel

Leading Candidate Fuels

Density (kg/m3)FormulaStructureComponent Product Grades

AMJ-A C10H20 801AMJ-310

Branched cycloparaffin

AMJ-B C10H14 820~16% AMJ-3B

Branched aromatic

AMJ-700• 60% AMJ 310

AMJ-C C15H32 774Branched alkane

• 60% AMJ-310• 40% AMJ-3C

[ 10 ]CONFIDENTIAL & PROPRIETARY

Amyris Jet Fuel

Distillation

290

270

290

Jet A (Obs/Corr)

100% AMJ-310 (2 components)

230

250

190

210

Tem

pera

ture

170

190

Lab: Intertek Caleb Brett (Benecia, CA)

1500 10 20 30 40 50 60 70 80 90 100

Percent

[ 11 ]

( )

CONFIDENTIAL & PROPRIETARY

Amyris Jet Fuel

Distillation

290

270

290Jet A (Obs/Corr)

100% AMJ-310 (2 components)

50% AMJ-310 (2 components)

230

250

190

210

Tem

pera

ture

170

190

Lab: Intertek Caleb Brett (Benecia, CA)

1500 10 20 30 40 50 60 70 80 90 100

Percent

[ 12 ]

( )

CONFIDENTIAL & PROPRIETARY

Amyris Jet Fuel

Distillation

290

270

290Jet A (Obs/Corr)100% AMJ-310 (2 components)50% AMJ-310 (2 components)50% AMJ-700 (3 components)

230

250

190

210

Tem

pera

ture

170

190

Lab: Intertek Caleb Brett (Benecia, CA)

1500 10 20 30 40 50 60 70 80 90 100

Percent

[ 13 ]

( )

CONFIDENTIAL & PROPRIETARY

Amyris Jet Fuel

Fuel Production

Biomass Sugars Fermentation Bio Oil Hydro-processing AMJ

Superior Jet Fuel PropertiesSuperior Jet Fuel Properties

[ 14 ]

Jet fuel overviewEmbraer, GE, Azul and Amyris collaboration project

2009 2010 20122011

Demo flightcolaborationproject

Components rig testing

Performance andprojectannouncement to evaluate Amyrisrenewable jet fuel

Sustainability evaluation

emissions

Sustainability evaluation

Production process development

[ 15 ]

Thank youy

Luciana Di Cierodiciero@amyris.com

[ 16 ]

Specification Test Results – 1/2

[ 17 ]

Specification Test Results – 2/2

[ 18 ]

Combustor Rig – Light Off (Cold Start)

[ 19 ]

Combustor Rig – Lean Blow Out

[ 20 ]