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By: Maryam Nabihah binti Hajah
MustafaAzila Ariffin
Parkinson’s Disease
second most common neurodegenerative disorder
progressive loss of muscle controltrembling of the limbs and head while at
rest stiffness, slowness, and impaired balance. may become difficult to walk, talk, and
complete simple tasks.
What is Parkinson’s Disease?
• degenerative disorder of the CNS
• Substantia Nigra (SN) controls movement
• Cells die in SN (pars compacta) stops producing Dopamine
• Loss in muscle control
• Thalamus and Globus Palidus Interna became overly active
What causes PD?
Tremor at restBradykinesiaImpaired balance and coordinationMuscle rigidityStooped postureExpressionless faceDecreased sense of smell
Primary Symptoms
Autonomic Impairment• Constipation
• Urinary problems• Orthostatic
hypotension• Dysphagia• Excessive
salivation• Pains
Motor complications
• Dyskinesia• No
response• Dystonia
Problems with advancing Parkinson’s Disease
1. Idiopathic 2. Acquired3. Hereditary parkinsonism4. Parkinson plus syndrome
Classifications
Drug treatment (levodopa, dopamine agonists, MAO-B inhibitors)
Therapy (occupational, speech and language, physiotherapy)
Surgery- Deep brain stimulation
Treatment
Lewy Body Dementia
Progressive Supranuclear Palsy
Normal Pressure Hydrocephalus
Shy-Drager Syndrome
Other Related Diseases
Lloyd Tan Parkinson’s Trust FundMalaysian’s Parkinson’s Disease AssociationWorld Parkinson’s Disease day
BackgroundGenderAge
Parkinson In Malaysia
http://www.ncbi.nlm.nih.gov/pubmed/21448542
http://emedicine.medscape.com/article/1831191-overview
http://en.wikipedia.org/wiki/Parkinson's_disease#cite_note-Jankovic2008-0
http://www.pdmdcenter.com/articles/HopkinsWeb/index.html
http://www.lloydtan-trust.com/http://
www.nlm.nih.gov/medlineplus/parkinsonsdisease.html#cat57
http://parkinsons-disease.emedtv.com/parkinson's-disease/natural-cure-for-parkinson's-disease.html
Sources