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©Eastman Kodak Company, 20058/12/2005
Advances in Film / Advances in Film / Screen RadiographyScreen Radiography
Robert E. Dickerson
Senior Research AssociateHealth Imaging
Eastman Kodak Company
©Eastman Kodak Company, 20058/12/2005
AgX Photodetector
� Inorganic, digital photoconductor
� 1-4 µm pixel size
©Eastman Kodak Company, 20058/12/2005
AgX Photodetectors
� Light photons produced by intensifying screens are captured by each AgX crystal to produce stable latent image
� 4-30 photons needed for stable latent image
©Eastman Kodak Company, 20058/12/2005
AgX Photodetector
� Latent image formed by exposure is chemically amplified by development to yield viewable silver image
� Amplification factor >109
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©Eastman Kodak Company, 20058/12/2005
Tabular vs Conventional, 3-D crystals
©Eastman Kodak Company, 20058/12/2005
Cubic Grain Microcrystals
©Eastman Kodak Company, 20058/12/2005
Non Commercialized Micro crystals
©Eastman Kodak Company, 20058/12/2005
X-Wing Fighter
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©Eastman Kodak Company, 20058/12/2005
PACMAN
©Eastman Kodak Company, 20058/12/2005
Opportunities for Improved Film Design
� Higher contrast by control of grain size distribution and sensitivity
� Higher resolution film/screen systems� Improved quantum sensitivities of silver
halide microcrystals� Novel coating structures to improve film
processing rates� New display properties
©Eastman Kodak Company, 20058/12/2005
KODAK MIN-R EV FilmNew asymmetric coating structure, in conjunction with novel emulsions, optimizes image quality from toe to shoulder of the response and improves physical properties.
Screen
Primary Emulsio
n
Second
ary Emulsi
on
Support (Blue)
Antihala
tion Laye
r
Orienta
tion La
yer
Total
©Eastman Kodak Company, 20058/12/2005
� Novel silver halide microcrystals in the parenchymal emulsion contain shallow electron trapping dopants. In conjunction with the improved monodispersity of the grains, this allows it to achieve high contrast with a sharp toe.
� High contrast makes breast anatomy, including abnormalities, more visible
� Sharp toe might enable new optimization of imaging chain and better visualization of microcalcifications
Parenchymal Emulsion
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©Eastman Kodak Company, 20058/12/2005
Min-R EV 150 system vs. Min-R 2000 system
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Log E
Den
sity
Sharp toe is due to novel emulsion technology
Higher contrast is due to monodisperse cubic grains
High D-max and shoulder contrast is due to high opacity grains and backside emulsion
Results in greater overexposure latitude, which is due to higher upper scale contrast
Better visualization of breast parenchyma
X-ray Sensitometry
KODAK MIN-R EV 150 Screen vsKODAK MIN-R 2000 Screen
KODAK MIN-R 2000/2000 Screens
KODAK MIN-R EV & EV 150Screens
Results in whiter whites, more “sparkle,” improved visibility of microcalcifications
©Eastman Kodak Company, 20058/12/2005
©Eastman Kodak Company, 20058/12/2005
� Images were exposed to a density of ~1.9 in the center of the image
� Images made with a GE DMR mammographic unit
� Two imaging systems: MIN-R 2000 and MIN-R EV
� Eight kVps: 25-32
� Two anode/filter combinations: Mo/Mo and Rh/Rh
� Two duplicate sets
� Total of 64 images
� All processed in KODAK X-OMAT EX II Developer and Replenisher
©Eastman Kodak Company, 20058/12/2005
� CDMAM Phantom, Type 3.4, used in the study
� Gold disks range in diameter from 60 µm to2 mm, and in thickness from 30 nm to 2 µm
� Each square contains two identical disks, one in the center and one in a randomly chosen corner
� The task is to pick the corner containing the disk
©Eastman Kodak Company, 20048/12/2005
©Eastman Kodak Company, 20058/12/2005
� Score sheet from one observer for MIN-R 2000 Film/Screen, 26 kVp, Mo/Mo
� Blue indicates that the correct corner was identified
� Red indicates that the wrong corner was identified or that the observer said they could no longer detect the disks
©Eastman Kodak Company, 20048/12/2005
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©Eastman Kodak Company, 20058/12/2005
Phantom: CDMAM Phantom, Type 3.4
Results
System kVp Filtration CDMAM Exposure RelativeDetectability* Time (sec) Mid-line
Dose
MIN-R 2000 28 Mo/Mo 0 1.92 1.0MIN-R 2000 30 Rh/Rh −−−−2 0.60 0.4
MIN-R EV 28 Mo/Mo +2 1.68 0.9MIN-R EV 30 Rh/Rh 0 0.55 0.4
* Average relative column number
©Eastman Kodak Company, 20058/12/2005
� Because of the improved film properties (toe contrast, mid-scale contrast, speed) and improved screen properties (improved MTF, speed)
� MIN-R EV Systems demonstrate simultaneously high sharpness and low, high-frequency noise
� At 28 kVp, Mo/Mo, the MIN-R EV System will reduce the mid-line dose by 10%, yet provide better detection of the disks in the CDMAM Phantom than the MIN-R 2000 System
� At 30 kVp, Rh/Rh, the MIN-R EV System will provide similar detection of the disks in the CDMAM Phantom as a MIN-R 2000 System but at 40% the mid-line dose
SummarySummary
©Eastman Kodak Company, 20058/12/2005
Features oxidatively enhanced, high quantum efficiency AgX microcrystal that provides improved sensitivity
Support
Low Exposure RegionImaging Layer
(Provides improved resolution and visually adaptive contrast)
High Exposure Imaging Layer+ Gradient Crossover Control
KODAK Hyper Speed G Medical Film
©Eastman Kodak Company, 20058/12/2005
KODAK Hyper Speed G Medical Film
Hyper Speed G 0.30 logE faster
T-MAT G/RA
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©Eastman Kodak Company, 20058/12/2005
Radiographic Speed – Historical Timeline
� 1896: Paper used for media-based radiography. Calcium tungstate intensifying screens discovered. Relative speeds unknown (VERY low).
� 1912: Glass plate radiography. VERY low speed.
� 1918-1970s: Double-emulsion films, calcium tungstate screens improved, relative system speeds 25-200.
� 1970s – present: Rare earth screens and appropriate films commercialized, relative system speeds 100-400 (A few small niche markets use faster systems).
� 2004: Hyper-speed systems, relative system speeds 400-1600 (with greatly improved high-frequency NEQ and DQE).
©Eastman Kodak Company, 20058/12/2005
Modulation Transfer Function (image blur)
MTF (cycles/mm)Screen / Film Speed 2 4 8
LANEX Regular / T-MAT G 400 100% 100% 100%
X-SIGHT / Hyper Speed G 800 175% 250% 270%LANEX Fast / Hyper Speed G 1300 90% 95% 100%
©Eastman Kodak Company, 20058/12/2005
Modulation Transfer Function (image blur) MTF (cycles/mm)
Screen / Film Speed 2 4 8
LANEX Regular / T-MAT G 400 100% 100% 100%
INSIGHT Skeletal Medium / Hyper Speed G 400 250% 500% 750%LANEX Fine / Hyper Speed G 200 300% 600% 900%
GE Digital Radiography 200-400 150% 60% NAComputed Radiography 200-400 90% 60% NA
©Eastman Kodak Company, 20058/12/2005
How Hyper Speed Works, cont.
MTF benefit can be utilized in two MTF benefit can be utilized in two basicbasic waysways::
1.1. Provide improved image quality (better visibility Provide improved image quality (better visibility of fine detail) at current system speeds.of fine detail) at current system speeds.
OROR2.2. Provide clinically acceptable, high image quality Provide clinically acceptable, high image quality
at 2X current system speeds, exchanging potential at 2X current system speeds, exchanging potential
image quality for radiation dose reduction.image quality for radiation dose reduction.
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©Eastman Kodak Company, 20058/12/2005
What does this mean?
�� MammographicMammographic – MTF at 200200--300300 speed
�� XX--SIGHTSIGHT – MTF at 800800 speed
�� LANEX Regular/TLANEX Regular/T--MATMAT – MTF at 13001300 speed
©Eastman Kodak Company, 20058/12/2005
Benefits of High-Speed Systems
�� Higher image quality from stopping motionHigher image quality from stopping motion
�� grids, body motiongrids, body motion
�� Opportunity to reduce KvOpportunity to reduce Kv
�� Smaller focal spotSmaller focal spot
�� MagnificationMagnification
�� Increased tube lifeIncreased tube life
�� Reduced radiation dose to radiology staffReduced radiation dose to radiology staff
©Eastman Kodak Company, 20058/12/2005
Visually Adaptive ContrastVisually Adaptive Contrast
� The human visual system loses it’s ability to distinguish differences in density as an image gets darker.
� This means that lesion detection is less likely if the lesion appears in a darker area of the radiograph.
Lesion Detection vs Density
Film Density
Les
ion
De
tect
abili
ty
DarkLight
More
Less
©Eastman Kodak Company, 20058/12/2005
Visually Adaptive Contrast
Visually Adaptive Contrast
Film Density
Les
ion
Det
ecta
bili
ty
DarkLight
More
Less
Visually adaptive contrast puts the contrast where the eyes need it.
Film
Con
tras
t
Higher
Lower
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©Eastman Kodak Company, 20058/12/2005
KODAK X-SIGHT L/RA Film
X-RAY SENSITOMETRYSPEED MATCHED AT D = 1.20
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log10 Relative Exposure
Gam
ma
T-MAT L/RA &LANEX RegularX-SIGHT L/RA &X-SIGHTXLA+ & TRIMATICRegular
Visually Adaptive ContrastLocal contrast comparison with other of Kodak’s latitude systems
©Eastman Kodak Company, 20058/12/2005
Summary
� New film/screen system allows for significantly reduced X-ray dose at improved MTF (image blur).
� Significant improvements in system MTF are possible at equivalent X-ray doses
� New film/screen system provide opportunities for dose reduction as result of higher system speed while maintaining high image quality
©Eastman Kodak Company, 20058/12/2005
� Improved film/screen systems continue to be developed.
� Opportunities for improved image quality and processability still exist.
� New systems provide possibilities for lower-dose radiology at high image quality.
Conclusion
©Eastman Kodak Company, 20058/12/2005