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SCIENCE & TECHNOLOGY
University of Wisconsin-Madison, Wisconsin Institutes for DiscoveryDesign Architect: Ballinger
Photo: © Jeff Goldberg / Esto
By identifying and validating the newest techniques,
technologies, and processes emerging in the market,
AEI’s Science & Technology practice can anticipate our clients’ goals to optimize
and extend their capital investments.
King Abdullah University of Science and TechnologyArchitect of Record: Hellmuth, Obata + Kassabaum, Inc.
Photo: © 2009 J.B. Picoulet - S. Lourié
U.S. Department of Energy / National Renewable Energy Laboratory, Energy System Integration FacilityDesign Architect: SmithGroupJJR
Photo: Dennis Schroeder / NREL
University of Washington School of Medicine, South Lake Union Campus Phase 3.1Architect of Record: Perkins+Will
Photo: © 2013 Benjamin Benschneider All Rights Reserved
PRECISION LAB ENVIRONMENTS
Research applications for lasers, optics, and other critical precision lab environments require stringent, stable conditions, often comparable to biotech and pharma cleanroom for temperature, humidity, and particulate levels. Extremely narrow parameters present a high degree of engineering difficulty, met with precision temperature/humidity sensing devices and individual lab-dedicated air handling units with fast-acting controls.
Projects shown (from left to right):
The University of Arizona, Health Sciences Education BuildingDesign Architect: CO Architects
Photo: Bill Timmerman
University of North Carolina at Chapel Hill, Genome Sciences BuildingArchitect of Record: Skidmore, Owings & Merrill LLP
Photo: Tom Rossiter
Northwestern University, Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center Architect of Record: Perkins+Will
Rendering courtesy of Perkins+Will
University of Wisconsin-Madison, Wisconsin Institutes for Medical ResearchDesign Architect: Hellmuth, Obata + Kassabaum, Inc.; Architect of Record: Zimmerman Architectural Studios, Inc.
Photo: C&N Photography, Inc.
University of Southern California, The Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell ResearchArchitect of Record: Zimmer Gunsul Frasca Architects LLP
Photo: Nick Merrick © Hedrich Blessing 2010
Houston Methodist Hospital Research InstituteArchitect of Record: WHR Architects, Inc., Design Architect: Kohn Pedersen Fox Associates PC
Photo: ©Aker/Zvonkovic Photography, Houston, Texas
U.S. Department of Energy / National Renewable Energy Laboratory, Energy Systems Integration FacilityDesign Architect: SmithGroup JJR
Photo: Dennis Schroeder / NREL
University of Washington Life Sciences BuildingDesign Architect: Perkins+Will
Rendering courtesy of Perkins+Will
Stony Brook University, Advanced Energy Research and Technology CenterArchitect of Record: Flad Architects
Photo: Steve Hall © Hedrich Blessing
AEI’s additional “Lab of the Year” honors, Awarded by R&D Magazine
BAUSCH & LOMB, INC.Optics Center Laboratory
BAYER CORPORATIONBuilding 36 Research Facility
FRED HUTCHINSON CANCER RESEARCH CENTERWeintraub Basic Sciences and Hutchinson Human Biology Buildings (Phase I)
GENENTECH, INC.Process Science Center - Phase I and II
INDIANA UNIVERSITYSimon Hall
NOVARTIS (FORMERLY CHIRON CORPORATION)Building 4 Campus Development Plan - Phase One Research Lab
PFIZER INC.Building Q, Life Science Research Building
U.S. DEPARTMENT OF AGRICULTUREDairy Forage Research Center
UNIVERSITY OF CALIFORNIA, RIVERSIDE School of Medicine Research Building
UNIVERSITY OF SOUTHERN CALIFORNIAThe Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research
LANDMARK BUILDINGS FOR LANDMARK RESEARCH
QUANTIFYING FLEXIBILITY
The rate of change in research and research funding compels owners to require and designers to provide flexible facilities. By applying meaningful metrics to levels of flexibility and adaptability, we can begin to quantify a return on investment, establishing a basis for decision-making and ensuring value. A body of benchmark data supports a cost-benefit methodology similar to that used to test and verify high performance design strategies.
SMARTER LABS
In the larger context of aggressive facility performance goals now reflected in new codes, rating systems, and owner priority, “smarter” lab strategies achieve a more energy- and water-efficient lab environment while maintaining or enhancing safety levels. Smarter control logic, integrating HVAC systems and digital controls with space-by-space real time air quality and occupancy sensor feedback loops can help cut facility energy use by as much as 50%. Intentional selection of efficient equipment can similarly cut process loads by 50%.
Nick Merrick © Hedrich Blessing 2015
Temperature, °C
35.0000034.0625033.1250032.1875031.2500030.3125029.3750028.4375027.5000026.5625025.6250024.6875023.7500022.8125021.8750020.9375020.00000
Velocity, m/s
0.5000000.4687500.437500.04062500.3750000.3437500.3125000.2812500.2500000.2187500.1875000.1562500.1250000.0937500.0625000.0312500.000000
Supporting the collaboration of theorists and experimentalists developing products in the fields of material sciences, medicine, chemistry, biology, synthesis, and other emerging areas of research, the engineered systems of the Eckhardt Research Center balance whole-building performance requirements and leverage space-specific efficiency opportunities to provide precision research environments, building-wide flexibility, and ideal office and collaborative spaces.
Two levels below grade, six labs house lasers and high performance optics used in experimental research related to spintronics, quantum information, and nanoscale sensing. Precision temperature/humidity sensing devices and individual dedicated air handling units with fast-acting controls and magnetic actuated valves maintain environmental requirements of 72°F ±0.5° and 37.5% RH ±2%. Two high-performance Class 10,000 optics labs meet requirements of 70°F ±0.5° and 37.5% RH ±2%. Designed without identified users, upper level labs can accommodate computational, wet (chemistry, biology), dry (physics/astronomy), or damp configuration without alteration to primary engineering infrastructure, using corridor access for maintenance and modification. The building also includes a sub-grade 10,000 gsf nano-fabrication clean room.
The facility is engineered to LEED Silver standards, with efficiencies specific to precision lab, flex lab, public, and collaboration spaces including variable air volume, total energy wheel technology, low flow fume hoods, reduced (unoccupied) air change rates, variable speed exhaust, run-around heat recovery, modular heat pump chillers, radiant floor heating, and active chilled beams. The Eckhardt Research Center improves energy use over ASHRAE 90.1-2007 by 26%, an annual energy savings valued at $240,000.
COMPLETION DATE
LOCATION
GROSS SQ. FT.
DESIGN ARCHITECT
2015
CHICAGO, ILLINOIS
277,000
HOK
The University of Chicago
William Eckhardt Research Center
© Tom Rossiter
PRECISION RESEARCH ENVIRONMENTS
BUILDING-WIDE FLEXIBILITY
SPACE-SPECIFIC EFFICIENCY
AEI utilized CFD modeling to plan, design, and verify air delivery strategies to provide the desired temperature and air velocity profiles at the optical table. Images below show projected temperature and air velocity performance.
The Allen Institute for Brain Science sought optimal integration of experiments, modeling, and theory by consolidating operations in a single facility that could also accommodate a high-capacity data center capable of handling petabytes of research content. Wet and dry labs in the Allen Institute building alternate with workspaces, grouped around a six-story center atrium. Collaboratively delivered, the facility also includes an electron microscopy area and education center. The LEED® Gold Allen Institute building additionally houses the Allen Institute for Cell Science and the Paul G. Allen Frontiers Group.
Early modeling and analysis led to incorporation of a radiant-heated and -cooled ceiling system, chilled beams, heat pump-enhanced heat recovery, flywheel-technology uninterruptible power supply, and a centralized daylight-harvesting control system. AEI developed system concepts for the 6,000 gsf, hot-aisle/cold-aisle data center, establishing criteria defining reliability and redundancy for appropriate resiliency, and creating an air handling configuration that employs heat generated by the data center to preheat the 100% outside air supplied to the entire building, contributing to a 26% reduction in annual energy costs, from baseline.
Allen Institute for Brain Science
Allen Institute Building
TEAM SCIENCE
BIG SCIENCE
OPEN SCIENCE
Based on the NIH concept that advances in patient care occur most effectively in a translational manner of bench to bedside, the Altman Clinical and Translational Research Institute building supports a collaborative continuum of laboratory research, clinical research, clinical trials, and community- and population-based investigations. The institute includes researchers in every phase of discovery within this highly sustainable interdisciplinary facility. AEI collected metered energy use data from similar laboratories to refine system sizes, performed comprehensive net zero energy life-cycle cost analysis in the design concept phase, and evaluated designs to minimize HVAC loads and maximize daylighting, to target a 20% improvement in performance over the California energy code.
Active chilled beams with individual space controls, heat recovery chillers, variable air volume ventilation, low-temperature hot water heating, occupancy sensors, variable velocity discharge exhaust, and right-sized electrical equipment all contribute to optimal overall building energy performance. Exploiting the site’s 50-foot downward slope to conceal a 1.5 million-gallon thermal energy storage tank, the facility employs a strategy more typically seen in central utility applications, accessing off-peak chiller capacity to cool the building the following day. The building is projected to use 22% less energy than the ASHRAE 90.1-2007 baseline standard, for an estimated annual cost savings of $318,000.
University of California, San Diego
Altman Clinical and Translational Research Institute
BENCH TO BEDSIDE
BIOMEDICAL INFORMATICS
A BIG THERMAL ENERGY STORAGE TANK
Rendering courtesy of ZGF Architects LLP
COMPLETION DATE
LOCATION
GROSS SQ. FT.
DESIGN ARCHITECT
2015
SEATTLE, WASHINGTON
270,000
PERKINS+WILL
COMPLETION DATE
LOCATION
GROSS SQ. FT.
DESIGN ARCHITECT
2016
SAN DIEGO, CALIFORNIA
360,000
ZGF ARCHITECTS LLP
Illustration © Affiliated Engineers, Inc.
Nick Merrick © Hedrich Blessing 2015
Collocating two research institutes – one public, one private – the Wisconsin Institutes for Discovery building was conceived as a readily integrative, highly sustainable research facility. Where those priorities overlap in providing rapid accommodation of new research needs and anticipating the longest possible building lifespan, flexibility insights pervade the now six-year old structure.
Research spaces are supported with reconfigurable overhead utility drops and “plug-and-play” accommodations for hoods and chilled beams. Balancing first costs with desire to support building changeability into the future, mechanical and electrical systems were sized to maximum capacity +10% to 20%. To date, roughly 12% of additional hood capacity has been engaged while a chilled beam per year has been added to meet additional cooling loads. Built-in capacity allows additional piped utilities, electrical outlets, air changes per hour, energy recovery for air systems, and other measures, and supports conversion from dry to wet lab, low hood to high hood demand, and office to lab space. Savings realized through IPD efficiencies in the project’s delivery were reinvested in space fit out, sustainability initiatives, and technology enhancements.
University of Wisconsin and Wisconsin Alumni Research FOUNDATION
Wisconsin Institutes for Discovery
INTEGRATIVE SUSTAINABLE
FLEXIBLE
Having seen greater flexibility made possible with a highly efficient open lab concept, Arizona State University is improving on that model with a higher lab space net-to-gross ratio, improving indirect cost recovery. The 193,000 sq. ft. Bio C building will function as a “workhorse” lab facility, accommodating interdisciplinary chemistry, engineering, and life sciences research in a transparent environment. It also includes highly sensitive spaces supporting a new cutting-edge compact linear accelerator and associated laser spaces
ASU experienced 100% turnover of lab spaces in the past ten years; research building renovation costs since 2005 totaled $38M. With flexible design measures in place, renovation-scale reconfiguration of Bio C will take 52% less time and cost 60% less than a comparable walled lab facility. Bio C will realize this degree of flexibility while achieving performance at a minimum of LEED Gold standards. In addition to reduced air change rates, demand-controlled ventilation, and decoupled zone cooling, Bio C will use an enhanced run-around loop to allow the flexibility of combined exhaust while providing efficiency superior to an energy recovery wheel. The project delivery model for Bio C is CMAR.
COMPLETION DATE
LOCATION
GROSS SQ. FT.
DESIGN ARCHITECT
Arizona State University
Biodesign Institute Building C
GREATER FLEXIBILITYBETTER FINANCIALS
HIGHER PERFORMANCE
FLEXIBLE LAB
Rendering courtesy of ZGF Architects LLP
PLANNING FOR FUME HOOD FLEXIBILITY | AEI collaborated with project lab planners and EH&S to specify VAV high performance hoods, offering flexibility of hood counts and future installation throughout the building.
Illustration © Affiliated Engineers, Inc.
COMPLETION DATE
LOCATION
GROSS SQ. FT.
ARCHITECT
2010
MADISON, WISCONSIN
300,000
BALLINGER, UIHLEIN WILSON ARCHITECTS
2018
TEMPE, ARIZONA
193,000
ZGF ARCHITECTS LLP
Alternative project delivery (APD) models offer potential immediate benefits to budget and schedule, but long-term quality and building performance are also imperative to the mission of the facility – to deliver landmark research. At a time of increased project complexity, higher regulatory standards, and advanced technology, project programs and their delivery have become ever more exacting. Details vary from Design Build, DB Competition, and DB/Bridging Document to Developer Led and Public-Private Partnership, but expertise in high performance facility design and the flexibility to plan for and deliver research program in every combination across the spectrum of APD models is essential for successful outcomes.
Scheduled for completion in 2018, the University of Kansas Integrated Sciences Building (ISB) will be the academic heart of the P3 Central District Development Project that also includes a new student union and new central utility plant. The result of a sciences master plan evaluation, the 260,000 sf ISB will provide teaching and research lab space, and collaborative spaces for students and faculty.
Design Architect: Perkins+Will; Rendering courtesy of Perkins+Will
University of Washington School of Medicine, South Lake Union Campus Phase 3.1Architect of Record: Perkins+Will; Photo: © 2013 Benjamin Benschneider All Rights Reserved
2014 INNOVATION PROJECT AWARD
The Vaccine and Gene Therapy Institute of FloridaArchitect of Record: Hellmuth, Obata + Kassabaum, Inc.; Photo: Moris Moreno
Design-Build Project/ Team AwardsAwarded by Design-Building Institute of America
Bayer Crop Science R&D FacilityArchitect of Record: Perkins+Will
The University of Arizona Cancer Center at Dignity Health St. Joseph’s Hospital and Medical CenterArchitect of Record: Zimmer Gunsul Frasca Architects LLP; Photo: Nick Merrick © Hedrich Blessing 2015
2016 NATIONAL AWARD OF EXCELLENCE: HEALTHCARE
2016 DISTINCTION AWARD, WESTERN PACIFIC REGION
UF Health, Springhill Medical Office BuildingArchitect of Record: Flad Architects
2013 BEST PROJECT, FLORIDA REGION2013 BEST PROJECT, FLORIDA REGION
© Jeff Goldberg / Esto
Alternative Delivery
THE University Of Kansas
P3 Central District Development
2016 DISTINCTION AWARD, WESTERN PACIFIC REGION
University of Arizona, Old Main RenovationDesign Architect: NTD Architecture; Architect of Record: Poster Frost Mirto
Air Force Technical Applications CenterDesign Architect: Hellmuth, Obata + Kassabaum, Inc.; Architect of Record: BRPH Companies Inc.; Photo: BRPH Architects-Engineers, Inc.
2016 BEST PROJECT, FLORIDA REGION
Diagram courtesy of ZGF Architects LLP
CONTACT:Steve Frei, PE, LEED AP Principal / National Market Leader, Science & Technologywork: 608.236.1238mobile: [email protected]
Blythe Vogt, PE, LEED AP Director of Business Developmentmobile: [email protected]
Paul Erickson, LEED AP BD+C Principal / Building Performance Practice Leaderwork: 608.236.1112mobile: 303.859.7523 [email protected]
SCIENCE andTECHNOLOGY
US DEPARTMENT OF ENERGYEnergy Systems Integration Facility
Architect: SmithGroupJJR
Photo by Dennis Schroeder / NREL
Further Science & Technology project experience.
aeieng.com
Allergan, Inc.
Amgen Inc.
Argonne National Laboratory
Arizona State University
Bayer Corporation
Baylor College of Medicine
Baxter Healthcare
Boehringer Ingelheim Pharmaceuticals
Boehringer Ingelheim Vetmedica
Bradley University
Brookhaven National Laboratory
Case Western Reserve University
Central Washington University
Chicago State University
College of DuPage
College of Lake County
College of William and Mary
Colorado State University
CUNY
Duke University
East Carolina University
Emory University
Eli Lilly and Company
Elizabeth City State University
Emory University
Florida Atlantic University
Florida Gulf Coast University
Florida International University
Florida State University
Fred Hutchinson Cancer Research Center
Genentech, Inc.
George Washington University
Houston Methodist Hospital
Illinois Institute of Technology
Illinois State University
Indiana University
Iowa State University
Johns Hopkins University
Johnson & Johnson
Kansas State University
Lawrence Berkeley National Laboratory
Lawrence Livermore National Laboratory
Loyola University Chicago
Marquette University
Memorial Sloan-Kettering
Michigan State University
Montana State University
NASA Johnson Space Center
NASA Kennedy Space Center
National Institutes of Health
National Institute of Standards and Technology
National Renewable Energy Laboratory
North Carolina State University
Northern Arizona University
Northern Illinois University
Northwestern University
Novartis
Oak Ridge National Laboratory
Oklahoma State University
Oregon Health & Science University
Oregon State University
Pacific Northwest National Laboratory
Purdue University
Roche
Rose-Hulman Institute of Technology
Southern Illinois University
Stanford University
State University of New York
Texas A&M University
The Ohio State University
The University of Chicago
The University of Chicago Medicine
The University of Texas at Austin
The University of Texas at Dallas
The University of Texas MD Anderson Cancer Center
The University of Texas Medical Branch
The University of Texas Southwestern Medical Center
University of Alabama
University of Alaska
University of Arizona
University of Arkansas
University of California, Berkeley
University of California, Davis
University of California, Irvine
University of California, Los Angeles
University of California, Riverside
University of California, San Diego
University of California, San Francisco
U.S. Department of Homeland Security (NBACC)
U.S. Department of Homeland Security (NBAF)
University of Central Florida
University of Cincinnati
University of Colorado at Boulder
University of Florida
University of Hawaii
University of Houston
University of Idaho
University of Illinois at Chicago
University of Illinois at Urbana-Champaign
University of Iowa
University of Kansas
University of Michigan
University of Minnesota Duluth
University of Minnesota Twin Cities
University of Missouri-Columbia
University of Nevada Las Vegas
University of New Mexico
University of North Carolina
University of Oklahoma
University of Pittsburgh Medical Center
University of Rochester
University of South Florida
University of Southern California
University of the Pacific
University of Utah
University of Virginia
University of Washington
University of Wisconsin- Eau Claire
University of Wisconsin- Green Bay
University of Wisconsin-Madison
University of Wisconsin-Milwaukee
University of Wisconsin-Platteville
University of Wisconsin- River Falls
University of Wyoming
Utah State University
Virginia Polytechnic Institute & State University
Wake Forest University
Western Carolina University
Western Illinois University
Western Michigan University
Western Washington University
Washington State University
AEI has been our essential partner in designing the sophisticated MEP systems required to support the complex research functions in the ACTRI building.
Michael Downs, Principal ArchitectUC San Diego
