Salman R. Khetani, PhD - irp-cdn.multiscreensite.com · Curriculum Vitae – S.R. Khetani (Updated: January 2020) 2 Jul 2001 – Feb 2006 Graduate Research Assistant Microscale Tissue

Salman R. Khetani, PhD University of Illinois at Chicago

851 S Morgan St, SEO 218 Chicago, IL 60607

Telephone: (312) 413-9424 Email: [email protected]

Lab website: http://mtm.uic.edu

EDUCATION Sept 2002 - Mar 2006 Ph.D., Bioengineering University of California at San Diego, La Jolla, California

Sept 2000 - Aug 2002 M.S., Bioengineering University of California at San Diego, La Jolla, California

Sept 1995 - Aug 2000 B.S., Electrical Engineering Marquette University, Milwaukee, Wisconsin

Sept 1995 - Jun 2000 B.S., Biomedical Engineering (Summa cum laude) Marquette University, Milwaukee, Wisconsin

POSITIONS Aug 2015 - Present Associate Professor (with tenure effective Aug 2018)

Department of Bioengineering University of Illinois at Chicago Chicago, Illinois

Oct 2011 - Aug 2015 Assistant Professor Department of Mechanical Engineering School of Biomedical Engineering

Colorado State University Fort Collins, Colorado

Oct 2011 – Nov 2016 Member, Scientific Advisory Board Hepregen Corporation

Medford, Massachusetts

Sept 2008 - Sept 2011 Co-founder and Director of Research Hepregen Corporation Medford, Massachusetts

Mar 2006 - Aug 2008 Postdoctoral Associate Lab for Multiscale Regenerative Tech. (PI: Sangeeta Bhatia) Harvard-M.I.T. Division of Health Sciences and Technology Cambridge, Massachusetts

Curriculum Vitae – S.R. Khetani (Updated: January 2020)

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Jul 2001 – Feb 2006 Graduate Research Assistant Microscale Tissue Engineering Lab (PI: Sangeeta Bhatia) University of California at San Diego La Jolla, California

Jun 1997 – Jun 2000 Co-op Intern (2 summers, 2 semesters) at GE Medical Milwaukee, Wisconsin

AWARDS AND HONORS

• NSF CAREER award, 2014-2019 • College of Engineering Advising Award, UIC, 2018 • Departmental Rising Star Award, UIC College of Medicine, 2018 • Honoring Our Professors' Excellence (HOPE) Award, UIC, 2018 • College of Engineering Teaching Award, UIC, 2017 • School of Biomedical Engineering Teaching Excellence Award, CSU, 2015 • Nominee, Best Professor of the Year Award, CSU Engineering College Council, 2015 • Nominee, George T. Abell Outstanding Early-Career Faculty Award, CSU, 2014 • Nominee, Honors Professor Award, CSU, 2014 • Poster Presentation (2nd place), Meeting of Int’l Society for the Study of Xenobiotics, 2010 • Poster Presentation (2nd place), California Tissue Engineering Meeting, 2003 • Awardee, NSF Graduate Research Fellowship, 2001-2004 • Honorable Mention, NSF Graduate Research Fellowship, 2000 • Poster Presentation (2nd place), Telemicroscopy Meeting, 2000 • Jacobs Fellowship, University of California at San Diego, 2000-2001 • Top Scholar in Biomedical Engineering Award, Marquette University, 2000 • Ignatius Scholarship, Marquette University, 1995-1999

MAJOR RESEARCH DIRECTIONS

The Microfabricated Tissue Models Lab (mtm.uic.edu) focuses on engineering the microenvironmental cues around human cells towards stabilizing their long-term phenotype in vitro for key applications in drug development (e.g. drug metabolism/toxicity screening and disease modeling for novel drug discovery) and regenerative medicine (i.e. cell-based therapies). We develop and utilize microfabrication tools, such as protein micropatterning, high-throughput extracellular matrix (ECM) microarrays, and microfluidic platforms to precisely control the microenvironment of both primary and iPSC-derived human cells in 2D and 3D culture formats depending on the hypotheses being posed. We utilize our model systems to mimic key aspects of diseases in vitro and elucidate underlying molecular mechanisms of disease progression as a function of cell-cell, cell-ECM, and cell-soluble factor interactions. Our organ of interest has been primarily the liver (e.g. drug-induced liver injury, non-alcoholic fatty liver disease and hepatitis B virus infection) and we have several publications in that space that are actively being cited in the field. More recently, we have expanded our repertoire to cardiomyocytes to study the underlying genetic determinants of atrial fibrillation in close collaboration with leading cardiologists and are also pursuing an intestinal


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culture platform to interface it with the liver for addressing key disease questions where both organs interact in the body. We are well funded, mostly through the National Institutes of Health (NIH) and National Science Foundation (NSF), to pursue the research directions above. Our long-term goals are to a) disseminate our engineered platforms to the wider academic and pharmaceutical communities for use in drug screening and mechanistic investigations, b) make fundamental discoveries into how underlying genetics and cell-microenvironment interactions dictate worsening of non-alcoholic fatty liver disease, hepatitis B virus infection, and atrial fibrillation outcomes in different patient populations to varying degrees, c) discover new molecular targets for the aforementioned diseases against which new drugs can be developed, and d) apply our cell culture expertise in vitro to implantable human tissues (i.e. biomanufacturing) for patients suffering from end-stage diseases and organ failure.

PEER-REVIEWED JOURNAL ARTICLES Total Citations: 4119 h-Index: 30 i10-index: 40 Source: Google Scholar (Updated January 2020) Under Review (preprint available on BioRxiv) 1. Kukla, D.A., Crampton, A.L., Wood, D.K.*, and Khetani, S.R.* Microscale Collagen and

Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models. Under peer review (2019) – BioRxiv preprint 10.1101/857789. *Co-corresponding authors

Published 2. Davidson, M.D., and Khetani, S.R.* Intermittent Starvation Extends the Functional Lifetime of

Primary Human Hepatocyte Cultures. Toxicological Sciences (in press) – BioRxiv preprint 10.1101/818203v1. *Corresponding author

3. Underhill, G.H.*, and Khetani, S.R.* Emerging Trends in Modeling Liver Disease In Vitro. APL Bioengineering 3(4):040902 (2019). *Co-corresponding authors

4. Ware, B.R., Brown, G.E., Soldatow, V.Y., LeCluyse, E.L., and Khetani, S.R.* Long-term Engineered Cultures of Primary Mouse Hepatocytes for Strain and Species Comparison Studies During Drug Development. Gene Expression – The Journal of Liver Research 19(3):199-214 (2019). *Corresponding author

5. Underhill, G.H.*, and Khetani, S.R.* Advances in Engineered Human Liver Platforms for Drug Metabolism Studies. Drug Metabolism and Disposition 46(11):1626-1637 (2018). *Co-corresponding authors

6. Brown, G., and Khetani, S.R.* Microfabrication of liver and heart tissues for drug development. Philos Trans R Soc Lond B Biol Sci. 373(1750), pii: 20170225 (2018). *Corresponding author


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7. Underhill, G.H.*, and Khetani, S.R.* Bioengineered liver models for drug testing and cell differentiation studies. Cellular and Molecular Gastroenterology and Hepatology 5(3):426-439.e1 (2017). *Co-corresponding authors

8. Meseguer-Ripolles, J., Khetani, S.R., Blanco, J.G., Iredale, M., Hay, D.C. Pluripotent Stem Cell Derived Human Tissue: Platforms to Evaluate Drug Metabolism and Safety. The AAPS journal 20(1):20 (2017) [Erratum in: AAPS J. 2018 Feb 12;20(2):30]

9. Ware, B.R., Durham, M.J., Monckton, C.P., and Khetani, S.R.* A cell culture platform to maintain long-term phenotype of primary human hepatocytes and endothelial cells. Cellular and Molecular Gastroenterology and Hepatology 5(3):187-207 (2017). *Corresponding author

10. Lin, C., Romero, R., Sorokina, L.V., Ballinger, K.R., Place, L.W., Kipper, M.J., and Khetani, S.R.* A polyelectrolyte multilayer platform for investigating growth factor delivery modes in human liver cultures. Journal of Biomedical Materials Research – Part A 106(4):971-984 (2017). *Corresponding author

11. Mosedale, M., Eaddy, J.S., Trask, O.J., Holman, N., Wolf, K.K., LeCluyse, E., Ware, B., Khetani, S.R., Lu, J., Brock, W.J., Roth, S.E., and Watkins, P.B. miR-122 release in exosomes precedes overt tolvaptan-induced necrosis in a primary human hepatocyte micropatterned coculture model. Toxicological Sciences 161(1):149-158 (2017)

12. Davidson, M.D., Kukla, D., and Khetani, S.R.* Microengineered cultures containing human hepatic stellate cells and hepatocytes for drug development. Integrative Biology 9(8):662-677 (2017). *Corresponding author (Featured on the journal cover)

13. Ware, B.R., Sunada, W., McVay, M., and Khetani, S.R.* Exploring chronic drug effects in microengineered human liver cultures using global gene expression profiling. Toxicological Sciences 157(2):387-398 (2017). *Corresponding author (Recommended by F1000Prime https://f1000.com/prime/727472597)

14. Lin, C., and Khetani, S.R.* Micropatterned co-cultures of human hepatocytes and stromal cells for the assessment of drug clearance and drug-drug interactions. Current Protocols in Toxicology 72:14.17.1-14.17.23 (2017). *Corresponding author

15. Ware, B.R and Khetani, S.R.* Engineered liver platforms for different phases of drug development. Trends in Biotechnology 35(2):172-183 (2016). *Corresponding author

16. Lin, C. and Khetani, S.R.* Advances in engineered liver models for investigating drug-induced liver injury. BioMed Research International 2016:1829148 (2016). *Corresponding author

17. Wang, W., Lockwood, K., Boyd, L., Davidson, M., Movafaghi, S., Vahabi, H., Khetani, S.R., and Kota, A.K. Superhydrophobic coatings with edible materials. ACS Applied Materials and Interfaces (29):18664-19668 (2016)

18. Neufeld, M.J., Ware, B.R., Lutzke, A., Khetani, S.R., and Reynolds, M.M. Water-stable metal-organic framework polymer composites compatible with human hepatocytes. ACS Applied Materials and Interfaces 8(30):19343-19352 (2016)

19. Davidson, M.D., Ballinger, K.R., and Khetani, S.R.* Long-term exposure to abnormal glucose levels alters drug metabolism pathways and insulin sensitivity in primary human hepatocytes. Scientific Reports 6:28178 (2016). *Corresponding author


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20. Lin, C., Shi, J., Moore, A., and Khetani, S.R.* Prediction of drug clearance and drug-drug interactions in microscale cultures of human hepatocytes. Drug Metabolism and Disposition 44(1):127-136 (2016). *Corresponding author

21. March, S., Trehan, K., Ramanan, V., Ng, S., Galstian, A., Scull, M.A., Shlomai, A., Mota, M., Fleming, H.E., Khetani, S.R., Rice, C.M., and Bhatia, S.N. Micropatterned co-cultures of primary human hepatocytes for the study of hepatotropic pathogens. Nature Protocols 10(12): 2027-2053 (2015)

22. Davidson, M.D.#, Ware, B.R.# and Khetani, S.R.* Stem cell-derived liver cells for drug testing and disease modeling. Discovery Medicine 19(106):349-358 (2015). #These authors contributed equally *Corresponding author

23. Lin, C#., Ballinger, K#., and Khetani, S.R.* The application of engineered liver tissues for novel drug discovery. Expert Opinion on Drug Discovery 10(5):519-540 (2015). #These authors contributed equally *Corresponding author

24. Nguyen, T., Ukairo, O., Khetani, S.R., McVay, M., Kanchagar, C., Seghezzi, W., Ayanoglu, G., Irrechukwu, O., and Evers, R. Establishment of a hepatocyte-Kupffer cell co-culture model for assessment of proinflammatory cytokine effects on metabolizing enzymes and drug transporters. Drug Metabolism and Disposition 43(5):774-785 (2015)

25. Ware, B., Berger, D., and Khetani, S.R.* Prediction of drug-induced liver injury in micropatterned co-cultures containing iPSC-derived human hepatocytes. Toxicological Sciences 145(2):252-262 (2015). *Corresponding author (Featured on the journal cover. Top 10% of most downloaded articles in the journal from 2015-2017)

26. Mitchell, A.M., Stone, A.E.L., Cheng, L., Ballinger, K., Edwards, M., Stoddard, M., Li, H., Golden-Mason, L., Shaw, G.M., Khetani, S.R, and Rosen, H.R. Transmitted/founder hepatitis C viruses induce cell type- and genotype-specific differences in innate signaling within the liver. mBio 6(2):e02510 (2015)

27. Khetani, S.R.*, Ballinger, K.R., Berger, D.R., Davidson, M.D., Lin, C., and Ware, B. Micro-engineered liver tissues for drug testing. Journal of Laboratory Automation 20(3):216-250 (2015). *Corresponding author

28. Davidson, M.D., Lehrer, M., and Khetani, S.R.* Hormone and drug-mediated modulation of glucose metabolism in a microscale model of the human liver. Tissue Engineering, Part C Methods 21(7):716-725 (2015). *Corresponding author

29. Berger, D.R, Ware, B.R, Davidson, M.D, Allsup, S.R., and Khetani, S.R.* Enhancing the functional maturity of iPSC-derived human hepatocytes via controlled presentation of cell-cell interactions in vitro. Hepatology 61(4):1370-1381 (2015). *Corresponding author

30. Giugliano, S., Golden-Mason, L., Dobrinskikh, E., Stone, A., Kriss, M., Soto-Guiterrez, A., Mitchell, A., Khetani, S.R., Shaw, G.M., Stolz, D., Yamane, D., Lemon, S.M., Gale, M., Shah, V., and Rosen, H.R. Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cell and release of exosomes, which inhibits viral replication. Gastroenterology 148(2):392-402.e13 (2015)

31. Schwartz, R.E., Fleming, H.E., Khetani, S.R., and Bhatia, S.N. Pluripotent stem cell-derived hepatocyte-like cells. Biotechnology Advances 32(2):504-513 (2014)


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32. Chan, T.S., Yu, H., Moore, A., Khetani, S.R. and Tweedie, D. Meeting the challenge of predicting hepatic clearance of compounds slowly metabolized by cytochrome P450 using a novel hepatocyte model, HepatoPac. Drug Metabolism and Disposition 41(12):2024-1032 (2013)

33. Ukairo, O., McVay, M., Krzyzewski, S., Aoyama, S., Rose, K., Andersen, M.E., Khetani, S.R.*, and LeCluyse, E.L. Bioactivation and toxicity of acetaminophen in a rat hepatocyte micropatterned co-culture system. Journal of Biochemical and Molecular Toxicology 27(10):471-480 (2013). *Corresponding author

34. Ukairo, O., Kanchagar, C., Moore, A., Shi, J., Gaffney, J., Aoyama, S., Rose, K., Krzyzewski, S., McGeehan, J., Andersen, M.E., Khetani, S.R.*, and LeCluyse, E.L. Long-term stability of primary rat hepatocytes in micropatterned co-cultures. Journal of Biochemical and Molecular Toxicology 27(3):204-212 (2013). *Corresponding author

35. Khetani, S.R., Kanchagar, C., Krzyzewski, S., Aleo, M., and Will, Y. Use of micropatterned co-cultures to detect compounds that cause drug induced liver injury in humans. Toxicological Sciences 132(1):107-117 (2013)

36. Wang, W.W., Khetani, S.R., Krzyzewski, S., Duignan, D.B., and Obach, R.S. Assessment of a micropatterned hepatocyte coculture system to generate major human excretory and circulating drug metabolites. Drug Metabolism and Disposition 38(10):1900-1905 (2010)

37. Ploss, A.*, Khetani, S.R.*, Jones, C.T., Syder, A. J., Trehan, K., Gaysinskaya, V.A., Mu, K., Ritola, K. D., Rice, C.M., and Bhatia, S.N. Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures. Proceedings of the National Academy of Sciences 107(7):3141-3145 (2010). *These authors contributed equally to this work

38. Jones, C.T., Catanes, M.T., Law, L.M., Khetani, S.R., Syder A.J., Ploss, A., Oh, T.S., Schoggins, J.W., MacDonald, M.R., Bhatia S.N., Rice, C.M. Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system. Nature Biotechnology 28(2):167-171 (2010)

39. March, S., Hui, E.E., Underhill G.H., Khetani, S., and Bhatia, S.N. Microenvironmental regulation of the sinusoidal endothelial cell phenotype in vitro. Hepatology 50(3): 920-928 (2009)

40. Chen, A.A.*, Khetani, S.R.*, Bhatia, S.N., and Van Vliet, K. J. Modulation of hepatocyte phenotype in vitro via chemomechanical tuning of polyelectrolyte multilayers. Biomaterials 30(6):1113-1120 (2009). *These authors contributed equally to this work

41. Khetani, S.R., Chen, A.A., Ranscht, B., and Bhatia, S.N. T-Cadherin Modulates Hepatocyte Functions In Vitro. FASEB Journal 22(11):3768-75 (2008)

42. Khetani, S.R., and Bhatia, S.N. Microscale human liver tissue for drug development. Nature Biotechnology 26(1):120-126 (2007)

43. Allen, J.W., Khetani, S.R., Johnson, R.S., and Bhatia, S.N. In vitro liver tissue model established from transgenic mice: role of HIF-1alpha on hypoxic gene expression. Tissue Engineering 12(11):3135-3147 (2006)

44. Khetani, S.R., and Bhatia, S.N. Engineering tissues for in vitro applications. Current Opinion in Biotechnology 17(5): 524-531 (2006)

45. Chen, A.A*., Derfus, A.M*., Khetani, S.R., and Bhatia, S.N. Quantum dots to monitor siRNA delivery and improve gene silencing. Nucleic Acids Research 33(22):190 (2005). *These authors contributed equally


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46. Khetani, S.R., Szulgit, G., Del Rio, J.A., Barlow, C., and Bhatia, S.N. Exploring interactions between rat hepatocytes and nonparenchymal cells using gene expression profiling. Hepatology 40(3):545-554 (2004)

47. Allen, J.W., Khetani, S.R., and Bhatia, S.N. In vitro zonation and toxicity in a hepatocyte bioreactor. Toxicological Sciences 84:110-119 (2004)

BOOK CHAPTERS 1. Monckton, C.P. and Khetani, S.R.* “Engineered Human Liver Co-cultures for Investigating

Drug-Induced Liver Injury”, Chapter 11 in Drug Induced Liver Toxicity, First Edition, doi: 10.1007/978-1-4939-7677-5. M. Chen and Y. Will (editors), Springer (2018) *Corresponding author

2. Ware, B.R. and Khetani, S.R.* “Micropatterned Co-Cultures of Induced Pluripotent Stem Cell-Derived Hepatocytes and Stromal Cells for Prediction of Drug-Induced Liver Injury”, Chapter 16 in Stem Cell-Derived Models in Toxicology, First Edition, doi: 10.1007/978-1-4939-6661-5. M. Clements and L. Roquemore (editors), Springer, p. 311-334 (2016) *Corresponding author

3. Hui, E.E, Khetani, S.R., and Bhatia, S.N. “Micromechanical control of cell-cell interactions”, Chapter 3 in Microdevices in Biology and Medicine, First Edition, ISBN-10: 1596934042. Y. Nahmias and S. N. Bhatia (editors), Artech House, p. 43-63 (2009)

4. Underhill, G.H., Khetani, S.R., Chen, A.A., and Bhatia, S.N. “Liver”, Chapter 48 in Principles of Tissue Engineering, Third Edition, ISBN-10: 0123706157. R. Lanza, R. Langer, and J.P. Vacanti (editors), Elsevier, p. 707-732 (2007)

5. Underhill, G.H., Felix, J., Allen, J.W., Tsang, V.L., Khetani, S.R., and Bhatia, S.N. “Tissue engineering of the liver”, Chapter 15 in Culture of Cells for Tissue Engineering. First Edition, ISBN-10: 0471629359. G. Vunjak-Novakovic and R.I. Freshney (editors), John Wiley and Sons, p. 417-473 (2006)

PUBLISHED ABSTRACTS IN CONFERENCE PROCEEDINGS 1. Lin, C., Heyward, S., Brown, C.A., and Khetani, S.R. Engineering Highly Functional Cocultures

of Cryopreserved Primary Human Hepatocytes and Kupffer Macrophages. Drug Metabolism Reviews 47 (Supplement 1): 168-169 (2015)

2. Khetani, S.R., Berger, D., Ware, B.R., and Davidson, M.D. Long-term Engineered Cultures of iPSC-derived Human Hepatocytes for Disease Modeling and Drug Screening. Hepatology 60 (Supplement S1): 179A (2014)

3. Ukairo, O., McVay, M., Krzyzewski, S., Rose, K., Anderson, M., Khetani, S., and LeCluyse, E. Bioactivation and Toxicity of Acetaminophen in Rat Primary Hepatocytes Cultured in Micropatterned Co-cultures. Drug Metabolism Reviews 45 (Supplement 1): 150 (2014)

4. McVay, M., Kanchagar, C., Khetani, S.R., and Ukairo, O. In Vitro Modeling of Cytokine-Drug Interactions Using Micropatterned Co-cultures of Primary Hepatocytes and Kupffer Macrophages. Toxicology Letters 221 (Supplement): S150 (2013)


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5. Ukairo, O., McVay, M., Kanchagar, C. and Khetani, S.R. A Micropatterned Culture with Human Hepatocytes and Kupffer Macrophages For Studying Inflammation-Drug Interactions. Drug Metabolism Reviews 44 (Supplement 1): 108 (2012)

6. Khetani, S.R. Microscale Engineered Models of the Liver For Drug Development. Drug Metabolism Reviews 43 (Supplement 2): 7 (2011)

7. Chan. T.S., Khetani, S.R., Moore, A., and Yu, H.B. Accurate Prediction of Hepatic Clearance For Low-Clearance Compounds Using Micropatterned Hepatocyte-Stromal Cell Co-Cultures. Drug Metabolism Reviews 43 (Supplement 2): 48 (2011)

8. Quinn, K., Nakamura, D., Zhang, H. Gauby, S., Lorentzen, C., Goldbach, E., Moore, A., Khetani, S.R., Liang, E., and Sauer, J.M. Be Careful What you Ask For: Challenges of Predicting Human Clearance For A Low Metabolic Turnover Compound, ELND006. Drug Metabolism Reviews 43 (Supplement 2): 49 (2011)

9. McVay, M., and Khetani, S.R. Global Gene Expression Changes Induced in Primary Human Hepatocytes by Thiazolidinediones Upon Repeat Dosing of HepatoPac Cultures. Drug Metabolism Reviews 43 (Supplement 2): 115-116 (2011)

10. Aoyama, S., Lambirth, S., and Khetani, S.R. A Long Term Culture Model For Primary Hepatocytes From Cynomolgus Monkeys. Drug Metabolism Reviews 43 (Supplement 2): 124 (2011)

11. Khetani, S.R., Krzyzewski, S.A., Moore, A., Wang, W.W., Duignan, D., and Obach, R.S. Investigation of Hepatotoxicity and Drug Metabolism In a Microsacle Model of the Human Liver. Hepatology 52 (Supplement): 366A (2010)

12. Khetani, S.R., Krzyzewski, S., Moore, A., Gaffney, J., McGeehan, J., Wang, W.W., Duignan, D., and Obach, R.S. Microscale Engineered Human Liver Model for Investigative Toxicology, Drug Metabolism and Efficacy Assessment. Drug Metabolism Reviews 42 (Supplement 1): 36-37 (2010)

13. Khetani, S.R., and Bhatia, S.N. Development and Characterization of Microscale Models of Rat and Human Livers. Hepatology 46 (Supplement): 773A (2007)

14. Martone, M.E., Peltier, S., Lamont, S., Gupta, A., Ludaescher, B., Khetani, S., Molina, T., and Ellisman, M.H. Increasing access to tomographic resources: web-based telemicroscopy and database. Microsc. Micronanal. 7 (Suppl 2: Proceedings Microscopy Society of America): 92–93 (2001)

PATENTS AND PATENT APPLICATIONS Granted Patents 1. US Patent No. 10266806B2. Stem Cell-Derived Hepatocytes in Co-Culture and Uses Thereof.

Khetani, S.R., Berger, D., and Ware, B (2019)

2. US Patent No. US9441202B2. Molecules with Effects on Cellular Development and Function. Bhatia, S.N. and Khetani, S.R. (2016) – continuation patent to US Patent No. 8617815

3. European Patent No. EP1904625B1. Microscale micropatterned engineered in vitro tissue. Bhatia, S.N. and Khetani, S.R. (2015)

4. Australian Patent No. AU2012216645B2. Microscale micropatterned engineered in vitro tissue. Bhatia, S.N. and Khetani, S.R. (2015)


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5. US Patent No. US8617815B2. Molecules with Effects on Cellular Development and Function. Bhatia, S.N. and Khetani, S.R. (2013)

Pending Patent Applications 6. US Patent Application US 2019/0071638 A1. Intermittent Starvation Techniques to Prolong

Functional Lifetime of Liver Cells In Culture. Davidson, M.D. and Khetani, S.R. (2018)

7. International PCT Application PCT/US16/61638. Compositions and Methods For Increasing Hepatocyte Functional Lifetime In Vitro. Davidson, M.D. and Khetani, S.R. (2016)

8. International PCT Application PCT/US16/45719. Engineered Platforms to Stabilize Both Hepatocytes and Endothelial Cells In Vitro. Ware, B., Durham, M. and Khetani, S.R. (2016)

9. International PCT Application PCT/US2016/039068. An Engineered Model of Fibrotic Diseases. Davidson, M.D. and Khetani, S.R. (2016)

10. International PCT Application PCT/US2015/011363. Stem Cell-Derived Hepatocytes in Co-Culture and Uses Thereof. Khetani, S.R., Berger, D., and Ware, B (2015)

11. International PCT Application PCT/US2014/045463. Hepatocytes In Co-Culture And Uses Thereof. Khetani, S.R. and Lehrer, M (2014)

12. International PCT Application PCT/US2013/030542. Systems and Methods for Studying Inflammation-Drug Interactions. McVay M., Kanchagar, C., Ukairo, O., and Khetani, S.R. (2013)

13. International PCT Application PCT/US2009/049849. Micropatterned Co-culture Systems as Infectious Disease Analysis Platforms. Bhatia, S.N., and Khetani, S.R. (2009)

14. International PCT Application PCT/US2006/020019. Microscale Micropatterned Engineered In Vitro Tissue. Bhatia, S.N. and Khetani, S.R. (2006)

RESEARCH GRANTS

Total funding (direct + indirect costs) attributed to S.R. Khetani: $6,370,594

Pending 1R01HL148444-01A1(PI: D. Darbar, Co-I: S. Khetani) NIH 04/01/20 - 03/31/25 $116,324 (Total: $3,580,260) – pending (13th percentile; 16th percentile payline)

Active 1R01HL150586-01(Multi-PI: D. Darbar, S. Khetani) NIH 1/17/20 - 12/31/23 $976,148 (Total: $2,502,943)

1R21ES028580-01A1 (Multi-PI: S. Khetani, G. Underhill) NIH 09/23/19 – 07/31/21 $409,024


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CBET-1933540 (PI: S. Khetani, Co-PI: M. Kipper) NSF 10/01/19 – 09/30/22 $300,000 (Total: $600,000)

1R21AI147137-01 (PI: S. Khetani) NIH 06/11/19 - 05/31/21 $426,992

Y6-003-CADMIM (PI: S. Khetani, Co-PI: D. Eddington) NSF 03/01/19 - 02/28/20 $36,133 (Total: $63,158)

1R01DK115747-01A1 (Multi-PI: S. Khetani, G. Underhill) NIH 02/08/18 - 01/31/22 $719,549 (Total: $1,380,334)

CBET-1706393 (PI: S. Khetani, Co-PI: D. Wood) NSF 09/01/17 - 08/31/20 $300,000 (Total: $600,000)

1R21ES027622-01 (PI: S. Khetani) NIH 04/01/17 - 03/31/20 $426,595 (NIEHS)

CAREER (CBET-1351909) (PI: S. Khetani) NSF 04/01/14 - 03/30/20 $405,886 Completed Y5-007-CADMIM (PI: S. Khetani, Co-PI: E. Hui) NSF 03/01/18 - 02/28/19 $31,146 (Total: $56,700)

W81XWH-14-C-0054 (PI: J. Papin, Co-PI: S. Khetani) DOD 02/01/14 - 01/31/17 $39,887 (Total: $1,250,000)

1R03AI115171-01 (PI: S. Khetani) NIH 12/01/14 - 11/30/16 $150,000 (NIAID)

1R03EB019184-01 (PI: S. Khetani) NIH 09/22/14 - 06/30/16 $158,865 (NIBIB)

Bioscience Discovery Evaluation Grant (PI: S. Khetani) Colorado 09/01/14 - 12/31/15 $71,000

Infectious Disease Supercluster (PI: S. Khetani) Colorado 07/01/13 - 06/30/14 $30,000

2R44FD003503-02 (PI: S. Khetani) FDA 9/17/10 - 09/16/11 $113,044

IIP-0956888 (PI: S. Khetani) NSF 01/15/10 - 12/31/11 $500,001

1RC1AA019624-01/02 (PI: S. Khetani) NIH 09/30/09 - 08/31/11 $910,000

1R43 FD003503-01 (PI: S. Khetani) FDA 09/20/08 - 04/30/09 $100,000

IIP-0810551 (PI: S. Khetani) NSF 07/01/08 - 06/30/09 $150,000


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INVITED TALKS 1. Khetani, S.R. “Liver Spheroids and Micropatterned Cultures for Drug Development” FutureTox

V: New technologies to evaluate organ-specific effects of drugs and chemicals, Chapel Hill, NC (Scheduled for November 2020)

2. Khetani, S.R. “Microengineered Human Liver Platforms for Drug Metabolism Studies” 23rd Microsomes and Drug Oxidations Meeting, Prague, Czech Republic (Scheduled for September 2020)

3. Khetani, S.R. “Microfabricated Liver Platforms for Drug Development” American Gastroenterological Association (Aga) Institute Council’s James W. Freston Single Topic Conference: GI Organoids and Engineered Organ Systems, Chicago, IL (Scheduled for August 2020)

4. Khetani, S.R. “Latest Advances in Microfabricated Human Liver Models for Studying Drug Disposition” 15th European ISSX (International Society for the Study of Xenobiotics) and EACPT (European Association for Clinical Pharmacology and Therapeutics) Joint Meeting, Geneva, Switzerland (Scheduled for June 2020)

5. Khetani, S.R. “Microfabricated Human Liver Tissues for Drug Development” Labroots’ 3rd Annual Drug Discovery & Development Virtual Conference (Scheduled for Feb 2020)

6. Khetani, S.R. “Engineering Human Liver Platforms for Drug Development and Disease Modeling” University of Wisconsin Department of Biomedical Engineering Seminar Series, Madison, WI (November 2019).

7. Khetani, S.R. “Functionally Stable Human Liver Co-cultures for Drug Development” BioIVT HepatoPac Users Group Meeting, San Diego, CA (October 2019).

8. Khetani, S.R., “Engineering phenotypically stable hepatocyte culture platforms for drug development” Hepatocyte Research Association Symposium at the 12th International Meeting of the International Society for the Study of Xenobiotics, Portland, OR (July 2019).

9. Khetani, S.R. “Functionally Stable Human Liver Co-cultures for Drug Development” BioIVT HepatoPac Users Group Meeting, San Francisco, CA (Jun 2019).

10. Khetani, S.R. “Microfabricated Liver Models for Disease Modeling and Drug Development” University of Kansas Medical Center Visiting Scientist Seminar Series, Kansas City, KS (Jun 2019).

11. Khetani, S.R. “Liver Cell Cocultures: Do These Discriminate Between Toxic and Non-Toxic Drugs?” AASLD/FDA Drug-Induced Liver Injury Conference, Hyattsville, MD (May 2019).

12. Khetani, S.R. “Engineering Human Liver Platforms for Drug Development and Regenerative Medicine” Center for Wound Healing and Tissue Regeneration’s Regenerative Sciences Seminar Series, University of Illinois, Chicago, IL (Apr 2019).

13. Khetani, S.R. “Engineering Microliver Platforms for Disease Modeling” Pulmonary Research Conference Series, University of Illinois, Chicago, IL (Mar 2019).

14. Khetani, S.R. “Scalable Miniature Human Tissues for Drug Development and Regenerative Medicine” Department of Bioengineering Seminar Series, University of California at San Diego, CA (Oct 2018).


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15. Khetani, S.R. “Investigation of Drug-Induced Liver Injury with Microfabricated Liver Platforms” Digestive Disease Week Annual Meeting, Washington, DC (June 2018).

16. Khetani, S.R., “Engineering Culture Platforms to Mimic Liver Diseases” Webinar organized by Lonza, Chicago, IL (May 2018).

17. Khetani, S.R. “Engineering Liver Tissues for Drug Development and Regenerative Medicine” Institute of Biomaterials, Tribocorrosion, and Nanomedicine 6th Annual Symposium, Chicago, IL (April 2018).

18. Khetani, S.R. “Engineered Human Liver Models for Disease Modeling” Brown University School of Medicine Seminar Series, Providence, RI (November 2017).

19. Khetani, S.R., and Ware, B.W. “Long-Term Microfluidic Human Liver Co-Cultures for Drug Development” Annual Meeting of the Biomedical Engineering Society (BMES), Phoenix, AZ (October 2017).

20. Khetani, S.R., “Engineering Miniature Livers for Drug Development and Regenerative Medicine” UIC College of Pharmacy Colloquium, Rockford, IL (September 2017).

21. Khetani, S.R., “Microengineered Liver Platforms for Multiple Applications in the Drug Development Pipeline” 14th European Meeting of the International Society for the Study of Xenobiotics, Cologne, Germany (June 2017).

22. Khetani, S.R., “The Utility of Hepatocyte Models for Predicting Drug Clearance and Drug-Transporter Interactions” 14th European Meeting of the International Society for the Study of Xenobiotics, Cologne, Germany (June 2017).

23. Khetani, S.R., “Microfabricated Liver Models for Stem Cell Differentiation and Regenerative Medicine” Stem Cell Seminar Series, University of Illinois, Chicago, IL (May 2017).

24. Khetani, S.R., “Engineering Miniature Liver Platforms for Drug Development and Regenerative Medicine” Department of Biomedical Sciences Seminar Series, University of Illinois, Rockford, IL (April 2017).

25. Khetani, S.R., “Physiological Micro-Liver Platforms for Drug Development” School of Biomedical Engineering Seminar Series, Purdue University, West Lafayette, IN (March 2017).

26. Khetani, S.R., “Primary Human Hepatocytes in the Drug Development Pipeline” Webinar organized by Lonza, Chicago, IL (March 2017).

27. Khetani, S.R., “Long-Lasting and Highly Functional Micro-Livers for Modeling Global Diseases” Division of Gastroenterology and Hepatology Seminar Series, University of Illinois at Chicago, Chicago, IL (February 2017).

28. Khetani, S.R., “Miniaturized Human Liver Constructs for Modeling Physiology and Disease” Department of Physiology Seminar Series, University of Illinois at Chicago, Chicago, IL (January 2017).

29. Khetani, S.R., “Engineering Micro-Livers for Drug Screening and Disease Modeling” Department of Biomedical Engineering Seminar Series, University of Miami, Miami, FL (January 2017).

30. Khetani, S.R., “The Utility of Microfabrication Technology for Maturing iPSC-Derived Human Hepatocytes” Annual meeting of the American Association of Pharmaceutical Scientists, Denver, CO (November 2016).


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31. Khetani, S.R., “Fatty Liver Disease on a Chip” The Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN (October 2016).

32. Khetani, S.R., “The Potential of Engineered Human Liver Co-Cultures in Phenotypic Drug Discovery for Liver Diseases” Webinar organized by Solvo Biotechnology, Chicago, IL (June 2016).

33. Khetani, S.R., “Microengineered Culture Platforms for Modeling Human Fatty Liver Disease” Chicago Diabetes Day at the University of Chicago, Chicago, IL (May 2016).

34. Khetani, S.R., “The Utility of Microscale Human Liver Co-Cultures for Investigating Drug Toxicity Outcomes” Webinar organized by Solvo Biotechnology, Chicago, IL (April 2016).

35. Khetani, S.R., “Microengineered Human Liver Models for Drug Screening and Disease Modeling” Keystone Symposia on Modern Phenotypic Drug Discovery: Defining the Path Forward, Big Sky, MT (April 2016).

36. Khetani, S.R., “Using Micropatterned Co-Cultures to Model Human-Specific Drug Metabolism, Disposition and Drug-Drug Interactions” Webinar organized by Solvo Biotechnology, Chicago, IL (March 2016).

37. Khetani, S.R., “Engineering Microscale Co-Cultures for Drug Screening and Disease Modeling” RTP-Drug Metabolism and Discussion Group Winter Symposium, Durham, NC (March 2016).

38. Khetani, S.R., “Microengineered iPSC-Derived Human Hepatocyte Models for Drug Development” Webinar organized by Solvo Biotechnology, Chicago, IL (January 2016).

39. Khetani, S.R., “Engineered Human Liver Cultures for Investigating HCV Pathogenesis” 35th Meeting of the US-Japan Cooperative Medical Sciences Program Hepatitis Panel, Bethesda, MD (January 2016).

40. Khetani, S.R., “Engineered Liver Models for Drug Development and Disease Modeling: From Bench to Marketplace” Innovation Medicine Program Seminar Series, University of Illinois, Chicago, IL (November 2015).

41. Khetani, S.R., “Predicting Clinically-Relevant Drug Disposition and Drug-Drug Interactions Using Micropatterned Co-cultures” Webinar organized by Hepregen Corporation, Chicago, IL (November 2015).

42. Khetani, S.R., “Engineered Human Liver Models for Investigating Drug Toxicity” The Liver Meeting®, San Francisco, CA (November 2015).

43. Khetani, S.R., “Engineered Liver Models for Drug Development and Disease Modeling” Roche Pharmaceuticals Seminar Series, Basel, Switzerland (November 2015).

44. Khetani, S.R., “Semiconductor-Driven Microscale Technologies to Create Organs-On-A-Chip: Case Study in the Liver” Illinois Ophthalmology Engineering Workshop, Chicago, IL (October 2015).

45. Khetani, S.R., “Microengineered Liver Models for Applications in Drug Development” Meet The Experts Transporter Conference, Boston, MA (October 2015).

46. Khetani, S.R., “Microengineered Human Liver Models for Drug Screening and Disease Modeling” Stem Cell Seminar Series, University of Illinois, Chicago, IL (October 2015).


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47. Khetani, S.R., “Engineering Stable Liver Models for Applications in Drug Screening and Disease Modeling” Department of Biomedical Engineering Seminar Series, Tufts University, Medford, MA (September 2015).

48. Khetani, S.R., “Microengineered Liver Models for Novel Drug Discovery” Bioengineering Seminar Series, University of Illinois, Chicago, IL (September 2015).

49. Khetani, S.R., “Engineering the Niche Around iPSC-Derived Liver Cells” Stem Cell Biotherapy Colloquium, Fort Collins, CO (April 2015).

50. Khetani, S.R., “Bioengineering Approaches for Creating Stable Liver Models” Medical University of South Carolina Seminar Series, Charleston, SC (March 2015).

51. Khetani, S.R., “Developing Microengineered Liver Models for Toxicology Research” Annual Meeting of the Society of Toxicology, San Diego, CA (March 2015).

52. Khetani, S.R., “Microengineered Liver Models for Disease Modeling” Children’s Research Institute Conference, Medical College of Wisconsin, Milwaukee, WI (February 2015).

53. Khetani, S.R., “Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of The Human Liver” Webinar organized by Hepregen Corporation, Fort Collins, CO (February 2015).

54. Khetani, S.R., “Microengineered Liver Models for Drug Screening and Disease Modeling” Mechanical Engineering Seminar Series, University of Colorado, Boulder, CO (January 2015).

55. Khetani, S.R., “Microscale Engineering Strategies to Create Functionally Stable Models of the Human Liver” Liver Research Center Seminar Series, Albert Einstein College of Medicine, Bronx, NY (December 2014).

56. Khetani, S.R., “Engineering Stable Liver Models for Applications in Drug Screening and Disease Modeling” University of Virginia, Charlottesville, VA (December 2014).

57. Khetani, S.R., “Engineering Stable Liver Models for Drug Screening and Disease Modeling” Bioengineering Seminar Series, University of Illinois, Chicago, IL (November 2014).

58. Khetani, S.R., “Engineering Stable Liver Models for Drug Screening and Disease Modeling” Department of Chemical and Petroleum Engineering Seminar Series, University of Wyoming, Laramie, WY (November 2014).

59. Khetani, S.R., “The Story of Hepregen Corporation: Bringing Engineered Liver Devices to the Marketplace” The Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014).

60. Khetani, S.R., “Engineering Culture Systems Using Primary and iPSC-Derived Liver Cells for Modeling Diseases and Drug Screening” Bioengineering Seminar Series, University of California, Berkeley, CA (October 2014).

61. Khetani, S.R., “Microscale Engineering Strategies to Functionally Mature iPSC-derived Human Hepatocytes” Webinar organized by Hepregen Corporation and Cellular Dynamics International, Fort Collins, CO (September 2014).

62. Khetani, S.R., “Engineering Stable Liver Models for Modeling Diseases In Vitro” University of Northern Colorado School of Biological Sciences Seminar Series, Greeley, CO (September 2014).


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63. Khetani, S.R., “Developing Micro-Engineered Cultures Using Primary and iPSC-Derived Liver Cells for Modeling Diseases and Drug Screening” University of Virginia Biomedical Engineering Seminar Series, Charlottesville, VA (September 2014).

64. Khetani, S.R., “Liver Tissue Engineering: Applications in Drug Screening and Disease Modeling” Colorado School of Mines Department of Chemical and Biological Engineering Seminar Series, Golden, CO (August 2014).

65. Khetani, S.R., “Developing Microengineered Models of the Liver for Toxicology and Disease Modeling” Wright-Patterson Air Force Base Seminar Series, Wright-Patterson AFB, OH (August 2014).

66. Khetani, S.R., “Microscale Engineering Approaches to Improve Liver Maturation of iPSC-derived Human Hepatocytes In Vitro” Cellular Dynamics International Users Group Meeting, Boston, MA (August 2014).

67. Khetani, S.R., “Enhancing the Functional Maturity and Longevity of iPSC-derived Human Hepatocytes Using Controlled Presentation of Cell-Cell Interactions In Vitro” FASEB Liver Biology Conference, Keystone, CO (July 2014).

68. Khetani, S.R., “The Micropatterned Co-culture Platform: Past, Present and the Future” Mid-Atlantic Hepregen User Group Meeting, West Conshohocken, PA (May 2014).

69. Khetani, S.R., “Engineering Long-lasting Models of the Liver for Drug Screening and Disease Modeling” Seminar at the University of Pennsylvania, Philadelphia, PA (May 2014).

70. Khetani, S.R., “The Role of Tissue Architecture in Optimizing Human Hepatocyte Functions In Vitro” Webinar organized by Hepregen Corporation for Pharmaceutical Scientists and Academics, Fort Collins, CO (May 2014).

71. Khetani, S.R., “Engineering Miniature Human Livers for Drug Screening” CSU Ventures Innovation Symposium, Fort Collins, CO (April 2014).

72. Khetani, S.R., “Engineering the Microscale Environment Around iPSC-Derived Human Hepatocytes In Vitro” Annual meeting of the Society of Toxicology, Phoenix, AZ (March 2014).

73. Khetani, S.R., “Microscale Culture of Human Liver Cells for Drug Development” Annual meeting of the American Association of Pharmaceutical Scientists, San Antonio, TX (November 2013).

74. Khetani, S.R., “Micro-engineered Models of the Liver for Drug Screening and Disease Modeling” University of Colorado Department of Bioengineering, Denver, CO (November 2013).

75. Khetani, S.R., “Exploring the Role of Cell-cell Interactions in Long-term Differentiated Functions of Induced Pluripotent Stem Cell-derived Human Hepatocytes” Cellular Dynamics International Users Group Meeting, Madison, WI (August 2013).

76. Khetani, S.R., “Co-culture Approaches to Create More Stable Models of the Liver” University of Colorado medical school, Denver, CO (July 2013).

77. Khetani, S.R., “Microfabrication and Co-culture Approaches for Creating More Stable Liver Models” The Hamner Institutes for Health Sciences, RTP, NC (July 2013).

78. Khetani, S.R., “Microfabrication Approaches for Creating More Stable In Vitro Liver Models” National Center for Toxicology Research of FDA, Little Rock, AR (May 2013).


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79. Khetani, S.R., “Engineered Approaches to Assess Liver Toxicity” Annual Meeting of the Society of Toxicology, San Antonio, TX (March 2013).

80. Khetani, S.R., "Microscale Engineered Models of the Liver for Drug Development and Modeling Disease" Physiology seminar series, Department of Biomedical Sciences, Colorado State University, Fort Collins, CO (February 2013).

81. Khetani, S.R., “Engineered Models of Liver Disease” Annual Meeting of the Society for Laboratory Automation and Screening, Orlando, FL (January 2013).

82. Khetani, S.R., “Engineered Models of Liver Diseases for Drug Development” Harvard's Wyss Institute Seminar, Boston, MA (December 2012).

83. Khetani, S.R., “Microscale Engineering of Tissue Models for Compound Screening” Annual Meeting of the Safety Pharmacology Society, Phoenix, AZ (October 2012).

84. Khetani, S.R., “Microscale Liver Models for Drug Development” Marquette University Biomedical Engineering Seminar, Milwaukee, WI (November 2011).

85. Khetani, S.R.*, “Engineered Tissue Models For In Vitro and In Vivo Metabolism and Toxicity Testing” American Meeting of the International Society for the Study of Xenobiotics, Atlanta, GA (October 2011). *Invited Chair of Plenary Session

86. Khetani, S.R., “Applications of microscale animal and human in vitro liver models in toxicology” Annual Meeting of the Society of Toxicology, Washington, DC (March 2011).

87. Khetani, S.R., “Investigation and Hepatotoxicity and Drug Metabolism in a Microscale Model of the Human Liver” The Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA (October 2010).

88. Khetani, S.R., “A Microscale Engineered Liver Platform for Compound Metabolism and Toxicity Studies” The Annual Meeting of the Northeast Chapter of the Society of Toxicology, Storrs, CT (October 2010).

89. Khetani, S.R., “Engineering Microscale Liver Models for Drug Development” The Annual Meeting of the Biomedical Engineering Society, Austin, TX (October 2010).

90. Khetani, S.R., “Assessing the Impact of Engineered Human Tissue Models for Drug Development and Research” Predictive In Vitro Models, Boston, MA (September 2010).

91. Khetani, S.R., “Engineering Microscale Models of the Liver for Drug Development and Toxicity Screening” Early Toxicity Screening, Seattle, WA (June 2010).

92. Khetani, S.R., “Miniaturized Microscale Liver Models for Drug Development” Lab Automation, Palm Springs, CA (January 2010).

93. Khetani, S.R., “Microscale Engineered Platforms for Hepatocyte Culture” The 5th Annual Hepatocyte Research Association, Baltimore, MD (October 2009).

94. Khetani, S.R., and Bhatia, S.N., “Microscale Liver Models for Drug Development and Toxicity Screening” Annual Meeting of the Society of Toxicology, Baltimore, MD (March 2009).

95. Khetani, S.R., and Bhatia, S.N., “Engineering Microscale Models of Human Liver Tissue for Drug Development” Boehringer-Ingelheim Seminar Series, Ridgefield, CT (February 2008).


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96. Khetani, S.R., and Bhatia, S.N., “Engineering Microscale Models of Human Liver Tissue for Drug Development” University of Virginia BME Department Seminar Series, Charlottesville, VA (February 2008).

97. Khetani, S.R., and Bhatia, S.N., “Microscale Hepatic Tissue Engineering” Center for the Study of Hepatitis C, Rockefeller University, New York, NY (October 2007).

98. Khetani, S.R., and Bhatia, S.N., “Microscale Hepatic Tissue Engineering” Predictive Human Toxicity and ADME/Tox Studies, Brussels, Belgium (January 2007).

99. Khetani, S.R., and Bhatia, S.N., “Microscale Engineered Human Liver Tissue for Drug Development” Annual Meeting of the Biomedical Engineering Society (BMES), Baltimore, MD (September 2005).

100. Khetani, S.R., and Bhatia, S.N., “Microscale Engineered Liver Tissue for Toxicant Testing” Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA (October 2004).

101. Khetani, S.R., Yeo, W-S., Szulgit, G., Del Rio, J.A., Mrksich, M., Barlow, C., and Bhatia, S.N., “Exploring Mechanisms of Cell-Cell Interaction in Hepatic Co-Cultures Using Gene Expression Profiling and Dynamic Substrates” Annual Meeting of the Biomedical Engineering Society (BMES), Nashville, TN (October 2003).

POSTER PRESENTATIONS 1. Khetani, S.R., Grown, G., and Ware, B. “A Novel Microfluidic Device to Mature Stem Cell-

Derived Human Liver Cells” Micro and Nanotechnology in Medicine Conference, Kauai, HI (Dec 2018).

2. Khetani, S.R., Kukla, D., Crampton, A., and Wood, D.K. “Engineering 3D Human Liver Microtissues Using Droplet-Based Microfluidics” Micro and Nanotechnology in Medicine Conference, Kauai, HI (Dec 2018).

3. Khetani, S.R., Kukla, D., Crampton, A., and Wood, D.K. “Fabrication of 3D Human Liver Microtissues using Droplet-based Microfluidics” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Irvine, CA (February 2018).

4. Khetani, S.R., Lin, C., Ballinger, K.R, Place, L.W., and Kipper, M.J. “Modulating Primary Human Hepatocyte Functions via Growth Factor Delivery from Chitosan-Heparin Polyelectrolyte Multilayers” Annual Meeting of the Society for Biomaterials, Minneapolis, MN (April 2017).

5. Khetani, S.R., and Lin, C. “Microengineered Stem Cell-Derived Human Liver Platform for Infectious Disease Applications” Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN (October 2016).

6. Khetani, S.R., and Davidson, M.D. “Investigating Human Hepatocyte-Stellate Cell Interactions in Microengineered Cultures” FASEB Liver Biology Conference, West Palm Beach, FL (June 2016).

7. Khetani, S.R., Davidson, M., Lehrer, M. “Hormone and Drug-mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver” FASEB Liver Biology Conference, Keystone, CO (July 2014).


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8. Khetani, S.R., “Microscale Engineered Human Liver Model for Investigative Toxicology, Drug Metabolism and Efficacy Assessment” Annual Meeting of the International Society for the Study of Xenobiotics, Istanbul, Turkey (September 2010).

9. Khetani, S.R., “Microscale Engineered Human Liver Model for Investigative Toxicology, Drug Metabolism and Efficacy Assessment” Annual Meeting of the International Society for the Study of Xenobiotics, Istanbul, Turkey (September 2010).

10. Khetani, S.R., and Bhatia, S.N., “Development and Characterization of Microscale Models of Rat and Human Livers” Annual Meeting of the American Association of the Study of Liver Diseases, Boston, MA (Nov 2007).

11. Khetani, S.R., and Bhatia, S.N., “Microscale Human Liver Tissue for Drug Development” Gordon Research Conferences – Drug Metabolism, Plymouth, NH (July 2007).

12. Khetani, S.R., and Bhatia, S.N., “Microscale Engineered Human Liver Tissue for Drug Development” Annual Symposium of the Computational and Systems Biology Group at MIT, Cambridge, MA (February 2007).

13. Khetani, S.R., and Bhatia, S.N., “Microscale Engineered Liver Tissue for Drug Development” Annual Meeting of the Biomedical Engineering Society (BMES), Chicago, IL (October 2006).

14. Khetani, S.R., Ranscht, B., and Bhatia, S.N., “T-cadherin Modulates Hepatocyte Functions In Vitro” Gordon Research Conference - Cell Contact and Adhesion, Andover, NH (June 2005).

15. Khetani, S.R., Yeo, W-S., Szulgit, G., Del Rio, J.A., Mrksich, M., Barlow, C., and Bhatia, S.N., “Exploring Cell-Cell Interactions Using Gene Expression Profiling and Dynamic Substrates” California Tissue Engineering Meeting, La Jolla, CA (September 2003).

16. Khetani, S.R., Szulgit, G., Del Rio, J.A., Barlow, C., and Bhatia, S.N., “Exploring Mechanisms of Cell-Cell Interaction in Hepatic Co-cultures Using Gene Expression Profiling” Annual Meeting of the Biomedical Engineering Society (BMES), Houston, TX (October 2002).

17. Khetani, S.R., Yeo, W-S., Szulgit, G., Del Rio, J.A., Mrksich, M., Barlow, C., and Bhatia, S.N., “Exploring Cell-Cell Interactions Using Gene Expression Profiling and Dynamic Substrates” Federation of American Societies for Experimental Biology (FASEB) Meeting on Mechanisms of Liver Growth, Development and Disease, Snowmass, CO (August 2004).

18. Khetani, S.R., Szulgit, G., Del Rio, J.A., Barlow, C., and Bhatia, S.N., “Exploring Mechanisms of Cell-Cell Interaction in Hepatic Co-cultures Using Gene Expression Profiling” Southern California Tissue Engineering Symposium, Los Angeles, CA (September 2002).

19. Khetani, S.R., Szulgit, G., Del Rio, J.A., Barlow, C., and Bhatia, S.N., “Exploring Mechanisms of Cell-Cell Interaction in Hepatic Co-cultures Using Gene Expression Profiling” American Association for the Study of Liver Diseases (AASLD) Meeting on Human Liver Cells in Biomedical Research, Warrenton, VA (June 2002).

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MENTORED STUDENT RESEARCH PRESENTATIONS Student presenter is underlined 1. Brown, G.E., Paik, N.Y., Pajcini, K.V., and Khetani, S.R. “Expansion of Hematopoietic Stem

Cells on a Liver Microenvironment Ex Vivo” Microfluidics for Hematology Workshop, Chicago, IL (Scheduled for April 2020). Oral presentation

2. Monckton, C.P., Brougham-Cook, A., Underhill, G.H., and Khetani, S.R. “Engineering Robust Chemomechanical Microenvironments for Human Hepatocytes Using Cell Microarrays” Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA (October 2019). Oral presentation

3. Yuan, Y., Li, J., and Khetani, S.R. “Engineered iPSC-derived Human Liver Platform for Hepatitis B Virus Drug Discovery” Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA (October 2019). Oral presentation

4. Panday, R., Kukla, D.A., Crampton, A.L., Wood, D.K., and Khetani, S.R. “Designing An Optimal Microenvironmental Niche for iPSC-derived Hepatocytes Via Droplet Microfluidics” Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA (October 2019). Poster presentation

5. Kukla, D., and Khetani, S.R. “Engineering Optimal 3D Human Liver Tissues Using Droplet Microfluidics” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2019). Poster presentation

6. Brown, G., and Khetani, S.R. “Long-term All Human Liver Model with Hepatocytes and Liver Fibroblasts” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2019). Poster presentation

7. Liu, J., and Khetani, S.R. “Determining Culture Conditions for the Fabrication of a Human Liver Platform Using Stem Cells” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2019). Poster presentation

8. Yuan, Y., and Khetani, S.R. “Elucidating Optimal Conditions for the Infection of a Stem Cell-Derived Human Liver Model with Hepatitis B Virus” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2019). Poster presentation

9. Panday, R., Szmelter, A., Eddington, D., and Khetani, S.R. “Modulating human liver cell function using 3D printed microfluidic oxygen delivery devices. Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2019). Oral and poster presentations

10. Brown, G., Ware, B.R., and Khetani, S.R. “Maturation of Stem Cell-Derived Human Hepatocytes in a Novel Microfluidic Device” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Oral presentation - Second place award

11. Kukla, D., and Khetani, S.R. “An Engineered Human Liver Platform for Investigating Non-alcoholic Fatty Liver Disease” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation - First place award


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12. Panday, R., Kukla, D., Crampton, A.L., Wood, D.K., and Khetani, S.R. “Microgel Platform for Investigating the Maturation of iPSC-hHs Using Liver-inspired Stromal Cells” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation - Second place award

13. Yuan, Y., Li, J., and Khetani, S.R. “Engineered stem cell-derived human liver platform to study chronic hepatitis B virus infection” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation

14. Liu, J., Li, D., Hui, E.E., and Khetani, S.R. “Micropatterning Strategies for Fabricating Functional Human Liver Models” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation

15. Monckton, C.P., Brougham-Cook, A., Kaylan, K., Underhill, G., and Khetani, S.R. “Microarray Platform to Investigate Synergies of Chemo-Mechanical Cues on Primary Human Hepatocytes” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation

16. Dabas, H., Monckton, C.P., and Khetani, S.R. “Characterization of Liver Sinusoidal Endothelial Cells in In Vitro Studies” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation

17. Ibrahim, D., Kukla, D., and Khetani, S.R. “Developing a Human Liver Platform with Hepatocytes and Stellate cells for studying Non-Alcoholic Fatty Liver Disease” UIC Bioengineering Research Symposium, Chicago, IL (April 2019). Poster presentation - Second place award

18. Kukla, D., Crampton, A., Wood, D.K., and Khetani, S.R. “Engineering 3D Human Liver Microtissues Using Droplet-Based Microfluidics” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Irvine, CA (Feb 2019). Poster presentation

19. Li, D., Liu, J., Hui, E., and Khetani, S.R. “High-Content Screening Platform for Multicellular Systems” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Irvine, CA (Feb 2019). Poster presentation

20. Brown, G., Ware, B., and Khetani, S.R. “Maturation of Stem Cell-Derived Human Hepatocytes in a Novel Microfluidic Device” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Oral presentation

21. Kukla, D.A., Crampton, A.L., Wood, D.K., and Khetani, S.R. “Fabrication of 3D Human Liver Microtissues Using Droplet-based Microfluidics” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Oral presentation

22. Monckton, C., and Khetani, S.R. “Fabrication of Phenotypically Stable Human Liver Co-cultures Using 4 Primary Cell Types” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Oral presentation

23. Brown, G., Ware, B., and Khetani, S.R. “Long-term 2D and 3D Human Liver Models with Hepatocytes and Liver Fibroblasts” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Poster presentation

24. Kukla, D.A., Stoppel, W., Kaplan, D., and Khetani, S.R. “Engineering a Long-term and Functional 3D Human Liver Model Using Silk Scaffolds” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Poster presentation


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25. Monckton, C., Kukla, D., Brougham-Cook, A., Underhill, G.H., and Khetani, S.R. “Engineering Optimal Chemo-Mechanical Substrates for Human Liver Cell Culture” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Poster presentation

26. Liu, J., and Khetani, S.R. “An Engineered Human Liver Cancer Co-Culture Platform for Novel Drug Discovery” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Poster presentation

27. Liu, J., and Khetani, S.R. “Engineering Human Hepatocyte and Cholangiocyte Co-cultures for Disease Modeling” Annual Meeting of the Biomedical Engineering Society, Atlanta, GA (Oct 2018). Poster presentation

28. Kukla, D., Davidson, M., and Khetani, S.R. “An Engineered Human Liver Platform for Investigating Interactions Between Non-alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus” Diabetes & Obesity Research Day, University of Illinois at Chicago, Chicago, IL (Oct 2018). Oral presentation

29. Kukla, D., Crampton, A., Wood, D.K., and Khetani, S.R. “Fabrication of 3D Human Liver Microtissues Using Droplet-based Microfluidics” Functional and Regenerative Materials Workshop, University of Illinois at Chicago, Chicago, IL (Oct 2018). Oral presentation

30. Kukla, D., Stoppel, W., Kaplan, D., and Khetani, S.R. “Engineering a Long-term and Highly Functional 3D Human Liver Model Using Silk Scaffolds” Functional and Regenerative Materials Workshop, University of Illinois at Chicago, Chicago, IL (Oct 2018). Poster presentation

31. Liu, J., Li, D.J., Hu, E.E., and Khetani, S.R. “High-content Screening Platform for Multicellular Systems” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (Sep 2018). Oral presentation

32. Panday, R.*, Yuan, Y.*, Crampton, A., Kukla, D., Li, J., Wood, D.K., and Khetani, S.R. “Scalable Microengineered Human Liver Platforms for Infectious Disease Applications” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (Sep 2018). *Authors contributed equally. Poster presentation

33. Kukla, D., Crampton, A., Wood, D.K., and Khetani, S.R. “A Droplet Microfluidic Platform for Fabricating Long-lasting 3D Human Liver Tissues” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (Sep 2018). Poster presentation

34. Brown, G., Ware, B.R., and Khetani, S.R. “A Novel Microfluidic Device for Controlled Maturation of Stem Cell-Derived Human Liver Cells” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (Sep 2018). Poster presentation

35. Monckton, C., Brougham-Cook, A., Kaylan, K., Underhill, G.H., and Khetani, S.R. “Microfabricated High-throughput Culture Platforms for Optimizing Liver Cell Micro-environments” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (Sep 2018). Poster presentation

36. Kukla, D., Crampton, A., Wood, D.K., and Khetani, S.R. “Fabrication of 3D Human Liver Microtissues using Droplet-based Microfluidics” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Oral presentation – First place award


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37. Kukla, D., Stoppel, W., Kaplan, D., and Khetani, S.R. “Engineering a Long-term and Highly Functional 3D Human Liver Model Using Silk Scaffolds” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

38. Ware, B.R., and Khetani, S.R. “Microfluidic Human Liver Co-cultures for Drug Screening and Disease Modeling” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

39. Ware, B.R., McVay, M., Sunada, W., and Khetani, S.R. “Exploring Chronic Drug Dosing in Engineered Human Liver Cultures Using Global Expression Profiling” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

40. Brown, G., Ware, B.R., and Khetani, S.R. “A Mouse Liver Platform for Investigating the Effects of Genetic Diversity on Drug Outcomes” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

41. Brown, G., Ware, B.R., and Khetani, S.R. “The Effects of Liver Fibroblast Populations on Primary Human Hepatocyte Functions In Vitro” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation - First place award

42. Liu, J.S., and Khetani, S.R. “Engineering Human Liver Cancer Culture Platforms for Drug Discovery” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

43. Liu, J.S., and Khetani, S.R. “Engineering Co-cultures of Primary Human Hepatocytes and Cholangiocytes for Disease Modeling” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

44. Pradella, F., and Khetani, S.R. “A Novel Serum-Free Medium Formulation for Human Liver Cultures” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

45. Ferrari, E., and Khetani, S.R. “An Optimized Microcontact Protein Printing Method with Applications in Human Liver Co-Cultures” UIC Bioengineering Research Symposium, Chicago, IL (April 2018). Poster presentation

46. Ware, B.R., and Khetani, S.R. “Microfluidic Human Liver Co-cultures for Drug Screening and Disease Modeling” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Irvine, CA (February 2018). Poster presentation

47. Ware, B.R., and Khetani, S.R. “Induced Pluripotent Stem Cell-Derived Human Liver Cells for Drug Toxicity Detection” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Irvine, CA (February 2018). Poster presentation

48. Ware, B.R., and Khetani, S.R. “Microfluidic Human Liver Co-cultures for Drug Screening and Disease Modeling” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2017). Poster presentation

49. Ware, B.R., and Khetani, S.R. “Long-term Engineered Cultures of Primary Mouse Hepatocytes for Genotype-Phenotype Studies” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2017). Poster presentation

50. Lin, C., and Khetani, S.R. “Microengineered Co-Cultures of Primary Human Hepatocytes and Kupffer Macrophages for Investigating Drug-Induced Liver Injury” Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) meeting, Chicago, IL (September 2017). Poster presentation


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51. Calzadilla, N., Lin, C., and Khetani, S.R. “Microengineered Co-cultures of Primary Human Hepatocytes and Kupffer Macrophages for Investigating Drug-induced Liver Injury” GEMS Research Symposium, Chicago, IL (September 2017). Oral presentation

52. Sorokina, L., Lin, C., and Khetani, S.R. “Decellularized Liver Extracellular Matrix for Long-Term Culture of Primary Human Hepatocytes” Student Research Forum, University of Illinois at Chicago, Chicago, IL (April 2017). Poster presentation

53. Lin, C. and Khetani, S.R. “Microengineered Co-cultures of Human Liver Cells for Studying Drug-Inflammation Interactions” BIOE 102 – Bioengineering Freshman Seminar, University of Illinois at Chicago, Chicago, IL (March 2017). Oral presentation

54. Kukla, D., Stoppel, W., Kaplan, D., and Khetani, S.R. “Engineering a Long-term and Highly Functional 3D Human Liver Model Using Silk Scaffolds” Annual Meeting of the Society for Biomaterials, Minneapolis, MN (April 2017). Poster presentation

55. Lin, C., and Khetani, S.R. “Microengineered Co-cultures of Primary Human Hepatocytes and Kupffer Macrophages for Investigating Drug-induced Liver Injury” Annual Meeting of the Society of Toxicology, Baltimore, MD (March 2017). Poster presentation

56. Ware, B., and Khetani, S.R. “Microfluidic Human Liver Co-cultures for Drug Screening and Disease Modeling” Annual Meeting of the Society for Laboratory Automation and Screening, Washington, DC (February 2017). Poster presentation

57. Lin, C., and Khetani, S.R. “Microengineered Co-cultures of Primary Human Hepatocytes and Kupffer Macrophages for Drug Disposition Studies” SBME seminar series, Colorado State University, Fort Collins, CO (February 2017). Oral presentation.

58. Ware, B., and Khetani, S.R. “Engineered In Vitro Platforms for Drug Toxicity Prediction and Elucidation” SBME seminar series, Colorado State University, Fort Collins, CO (January 2017). Oral presentation.

59. Davidson, M.D., and Khetani, S.R. “Investigating Steatosis and Insulin Resistance in Microengineered Human Liver Cultures” UIC Diabetes & Obesity Research Day, Chicago, IL (October 2016). Oral presentation

60. Kukla, D., Stoppel, W., Kaplan, D., and Khetani, S.R. “Engineering a Long-term and Highly Functional 3D Human Liver Model Using Silk Scaffolds” Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN (October 2016). Oral presentation

61. Davidson, M.D., and Khetani, S.R. “A Bioinspired Culture Medium Prolongs the Functional Lifetime of Human Liver Cells in Culture” Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN (October 2016). Poster presentation

62. Davidson, M.D., and Khetani, S.R. “Modeling the Early Stages of Fatty Liver Disease and Fibrosis in Microengineered Human Liver Cultures” Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN (October 2016). Poster presentation

63. Davidson, M.D., and Khetani, S.R. “Investigating steatosis and insulin resistance in microengineered human liver cultures” Chicago Diabetes Day at the University of Chicago, Chicago, IL (May 2016). Poster presentation (award winner)

64. Ware, B., and Khetani, S.R. “Microfabricated Co-Cultures Containing Induced Pluripotent Stem Cell-Derived Liver Cells for Drug Development” NanoEngineering for Medicine and Biology, Houston, TX (February 2016). Oral presentation.


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65. Allsup, S., Berger, D., and Khetani, S.R. “Maturation of Induced Pluripotent Stem Cell-Derived Human Liver Cells in Engineered Co-cultures” Annual Meeting of the Biomedical Engineering Society, Tampa, FL (October 2015). Oral presentation.

66. Davidson, M.D. and Khetani, S.R. “Engineering an In Vitro Model of Human Non-Alcoholic Fatty Liver Disease and Insulin Resistance” Annual Meeting of the Biomedical Engineering Society, Tampa, FL (October 2015). Oral presentation.

67. Durham, M., Ware, B., and Khetani, S.R. “Engineered Co-cultures of Primary Human Liver Sinusoidal Endothelial Cells and Hepatocytes” Annual Meeting of the Biomedical Engineering Society, Tampa, FL (October 2015). Poster presentation.

68. Lin, C. and Khetani, S.R. “Microengineered Co-cultures of Human Liver Cells for Studying Drug-Inflammation Interactions” Annual Meeting of the Biomedical Engineering Society, Tampa, FL (October 2015). Oral presentation.

69. Lin, C., Faulk, D.M., Badylak, S.F., and Khetani, S.R. “Decellularized Liver Extracellular Matrix for Long-term Culture of Human Liver Cells” Annual Meeting of the Biomedical Engineering Society, Tampa, FL (October 2015). Poster presentation.

70. Allsup, S., Berger, D., and Khetani, S.R. “Functional Maturation of iPSC-Derived Human Liver Cells in Engineering Co-cultures” Celebrate Undergraduate Research and Creativity (CURC) showcase at Colorado State University, Fort Collins, CO (April 2015). Poster presentation (undergraduate).

71. Ballinger, K. and Khetani, S.R. “Effect of Co-culture on Hepatic Cell Line Functions” School of Biomedical Engineering Symposium, Fort Collins, CO (March 2015). Poster presentation.

72. Berger, D., and Khetani, S.R. “Improving Functional Maturity of iPSC-derived Human Hepatocytes via Microfabrication” School of Biomedical Engineering Symposium, Fort Collins, CO (March 2015). Poster presentation.

73. Davidson, M. and Khetani, S.R. “Long-term Effects of Glucose Levels on Human Hepatocyte Functions” School of Biomedical Engineering Symposium, Fort Collins, CO (March 2015). Poster presentation.

74. Lin, C. and Khetani, S.R. “Co-culture of Human Hepatocytes and Kupffer Macrophages for Drug-Inflammation Interaction Studies” School of Biomedical Engineering Symposium, Fort Collins, CO (March 2015). Poster presentation.

75. Ware, B. and Khetani, S.R. “Optimizing Phenotype of Primary Mouse Hepatocytes Using Microscale Engineering Approaches” School of Biomedical Engineering Symposium, Fort Collins, CO (March 2015). Poster presentation.

76. Ballinger, K. and Khetani, S.R. “Improving Liver Functions of Hepatic Cell Lines in vitro” Colorado State University Graduate Student Showcase, Fort Collins, CO (February 2015). Poster presentation.

77. Berger, D., and Khetani, S.R. “Microscale Engineering Strategies to Functionally Mature iPSC-derived Human Hepatocytes” Colorado State University Graduate Student Showcase, Fort Collins, CO (February 2015). Poster presentation.

78. Davidson, M., Ballinger, K., and Khetani, S.R. “Mimicking Chronic Hypo- and Hyper-glycemia in Engineered Cultures of Hepatocytes” Colorado State University Graduate Student Showcase, Fort Collins, CO (February 2015). Poster presentation.


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79. Lin, C. and Khetani, S.R. “Engineering Cocultures of Primary Human Hepatocytes and Kupffer Macrophages” Colorado State University Graduate Student Showcase, Fort Collins, CO (February 2015). Poster presentation.

80. Ware, B., Soldatow, V., Berger, D., LeCluyse, E., and Khetani, S.R. “Long-Term Engineered Cultures of Mouse Hepatocytes for Genotype-Phenotype Studies” Colorado State University Graduate Student Showcase, Fort Collins, CO (February 2015). Poster presentation.

81. Ware, B., Berger, D., Davidson, M., and Khetani, S.R. “Prediction of Drug-Induced Liver Injury in Engineered Cultures of iPSC-Derived Human Hepatocytes” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Poster presentation.

82. Ware, B., Soldatow, V., Berger, D., LeCluyse, E., and Khetani, S.R. “Long-Term Engineered Cultures of Primary Mouse Hepatocytes for Genotype-Phenotype Studies” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Poster presentation.

83. Lin, C., Ballinger, K., Kipper, M., and Khetani, S.R. “Spatiotemporal Delivery of Growth Factors to Hepatocytes via Polyelectrolyte Multilayers” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Oral presentation.

84. Lin, C., Shi, J., Moore, A., and Khetani, S.R. “Modeling Drug Clearance and Drug-Drug Interactions in Long-Term Engineered Human Liver Cultures” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Poster presentation.

85. Lin, C., Heyward, S., Brown, C.A., and Khetani, S.R. “Engineering Highly Functional Cocultures of Cryopreserved Primary Human Hepatocytes and Kupffer Macrophages via Microfabrication” Annual Meeting of the International Society for the Study of Xenobiotics, San Francisco, CA (October 2014). Poster presentation.

86. Ware, B., Berger, D., Davidson, M., and Khetani, S.R. “Controlled Cell-Cell Interactions Enhance Functional Maturation of iPSC-Derived Human Hepatocytes” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Oral presentation.

87. Berger, D., McVay, M., and Khetani, S.R. “Exploring Chronic Drug Dosing in Engineered Human Liver Cultures Using Global Expression Profiling” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Poster presentation.

88. Ballinger, K., Bailey, A., and Khetani, S.R. “Improving Liver Functions of Hepatic Cell Lines in vitro by Co-Culture with Stromal Support Cells” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Poster presentation.

89. Davidson, M., Ballinger, K., and Khetani, S.R. “Mimicking Chronic Hypo- and Hyper-glycemia in Engineered Cultures of Human Hepatocytes” Annual Meeting of the Biomedical Engineering Society, San Antonio, TX (October 2014). Poster presentation.

90. Berger, D., and Khetani, S.R. “Microscale Engineering Strategies to Functionally Mature iPSC-derived Human Liver Cells” SBME seminar series, Colorado State University, Fort Collins, CO (September 2014). Oral presentation.

91. Davidson, M., and Khetani, S.R. “Investigating effects of over-nutrition and diabetes in engineered human liver cultures” SBME seminar series, Colorado State University, Fort Collins, CO (September 2014). Oral presentation.


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92. Ware, B., Berger, D., Davidson, M., and Khetani, S.R. “Evaluating drug induced liver injury with induced pluripotent stem cells in vitro” SBME seminar series, Colorado State University, Fort Collins, CO (April 2014). Oral presentation.

93. Lin, C., Shi, J., Moore, A., and Khetani, S.R. “Prediction of drug clearance and drug-drug interactions in micropatterned co-cultures of human hepatocytes” SBME seminar series, Colorado State University, Fort Collins, CO (April 2014). Oral presentation.

94. Davidson, M., Ware, B., Berger, D., and Khetani, S.R. "Microscale human liver model for assessing glucose metabolism and drug screening efforts in diabetes" CSU Ventures 2014 Innovation Symposium, Fort Collins, CO (April 2014). Poster presentation.

95. Lin, C., Shi, J., Moore, A., and Khetani, S.R., “Prediction of in vivo-relevant drug disposition in a micro-engineered model of the human liver” CSU Ventures 2014 Innovation Symposium, Fort Collins, CO (April 2014). Poster presentation.

96. Lin, C. and Khetani, S.R., “Drug clearance prediction in micropatterned co-cultures” Research Symposium – Colorado State University, Fort Collins, CO (March 2014). Poster presentation.

97. Berger, D. and Khetani, S.R., “Long-term engineered cultures of iPSC-derived human hepatocytes for drug screening” Research Symposium – Colorado State University, Fort Collins, CO (March 2014). Poster presentation.

98. Davidson, M., Lehrer, M., and Khetani, S.R. "Hormone and Drug-Mediated Modulation of Glucose Metabolism in a Microscale Model of the Human Liver" Annual Meeting of the Biomedical Engineering Society, Seattle, WA (September 2013). Oral presentation.

99. Berger, D., Ware, B., Davidson, M., Bailey, A., and Khetani, S.R., “Heterotypic Cell Interactions Enhance Liver Functions of iPSC-Derived Human Hepatocytes” Annual Meeting of the Biomedical Engineering Society, Seattle, WA (September 2013). Poster presentation.

100. Lin, C., Ware, B., Berger, D., and Khetani, S.R., “Prediction of In Vivo-Relevant Drug Disposition in a Micro-Engineered Model of the Human Liver” Annual Meeting of the Biomedical Engineering Society, Seattle, WA (September 2013). Poster presentation.

REVIEWER FOR MANUSCRIPTS IN PEER-REVIEWED JOURNALS 1. The AAPS Journal 2. Acta Biomaterialia 3. ACS Biomaterials Science & Engineering 4. Advanced Biosystems 5. Advanced Drug Delivery Reviews 6. ALTEX (Alternatives to Animal Experimentation) 7. American Journal of Pathology 8. Archives of Pharmacal Research 9. Artificial Cells, Nanomedicine and Biotechnology 10. Bioengineering 11. Biomacromolecules 12. Biomaterials 13. Biomedical Microdevices 14. Biomicrofluidics


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15. Biotechnology Advances 16. Biotechnology and Bioengineering 17. Biotechnology Journal 18. Cell Biology and Toxicology 19. Cellular and Molecular Gastroenterology and Hepatology 20. Cellular and Molecular Life Sciences 21. Cell and Tissue Research 22. Cell Stem Cell 23. Chemical Research in Toxicology 24. Current Medicinal Chemistry 25. Current Pharmaceutical Biotechnology 26. Cytotherapy 27. Data in Brief 28. Diabetes, Obesity and Metabolism 29. Disease Models & Mechanisms 30. DNA and Cell Biology 31. Drug and Chemical Toxicology 32. Drug Metabolism Letters 33. Drug Safety 34. Experimental Biology and Medicine 35. Expert Opinion on Drug Metabolism and Toxicology 36. European Journal of Cell Biology 37. FASEB Journal 38. Food & Function 39. Frontiers in Bioengineering and Biotechnology 40. Gastroenterology 41. Genes 42. Hepatology 43. IEEE Journal of Biomedical and Health Informatics 44. Integrative Biology 45. International Journal of Molecular Medicine 46. International Journal of Molecular Sciences 47. International Journal of Nanomedicine 48. Journal of Applied Toxicology 49. Journal of Biomedical Materials Research: Part A 50. Journal of Biomedical Materials Research: Part B - Applied Biomaterials 51. Journal of Cellular Physiology 52. Journal of Immunology and Regenerative Medicine 53. Journal of Physiology and Pharmacology 54. Journal of Tissue Engineering and Regenerative Medicine 55. Journal of Visualized Experiments 56. Lab on a Chip 57. Metabolites 58. Methods 59. Molecular Pharmaceutics 60. Nanobiomedicine 61. Nanomedicine 62. Nature Communications


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63. Philosophical Transactions of the Royal Society B 64. PLOS One 65. RSC Advances 66. Science Advances 67. Science Translational Medicine 68. Scientific Reports 69. Stem Cells International 70. Stem Cell Reports 71. Stem Cell Reviews and Reports 72. Technology 73. The ILAR journal 74. Tissue and Cell 75. Tissue Engineering 76. Tissue Engineering, Part C – Methods 77. Toxicology In Vitro 78. Toxicological Sciences 79. Trends in Biotechnology 80. Wiley-Blackwell Biotechnology Series 81. Xenobiotica

REVIEWER FOR ABSTRACTS SUBMITTED TO CONFERENCES

1. Tissue Engineering & Regenerative Medicine Int’l Society Americas (TERMIS-AM) (2016) 2. Nanoengineering for Medicine and Biology (2015) 3. Annual Meeting of the Biomedical Engineering Society (2014, 2015, 2016, 2017, 2018, 2019) 4. American Chemical Society National Meeting and Exposition (2014) 5. Society for Biomaterials Annual Meeting (2014)

REVIEWER FOR GRANTS SUBMITTED TO FUNDING AGENCIES 1. National Institutes of Health

- ZES1 LWJ-D (OC) (Apr 2020) - ZRG1 BST-R (10) (Mar 2020) - ZRG1 BST-R (10) (Nov 2019) - NIH-NIBIB U01 (July 2019) - BMBI (June 2019) - ZRG1 BST-F (80) A (May 2019) - ZRG1 DKUS-T (06) M (Mar 2019) - CMT (Oct 2018) - ZDK1 GRB-J O4 (Aug 2018) - HBPP (Jun 2018) - CMT (Feb 2018) - ZAI1-BLG-M-J1 (Dec 2016) - ZRG1 BST-W (90) (Nov 2016) - Superfund C Workgroup 2017/01 ZES1 LWJ-K (S2) 1 (Sep 2016)


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- NIH Director’s Early Independence Award (DP5) ZRG1 RPHB-W-53-R (Apr 2016) - Cutting-Edge Basic Research Awards (CEBRA) ZDA1 JXR-G (10) (Apr 2015) - HBPP (Feb 2014)

2. National Science Foundation - Biotechnology and Biochemical Engineering CAREER grant review panel (Sep 2015) - HBCU-UP Research Initiation Award review panel (Nov 2016)

3. Oak Ridge Associate Universities (ORAU) - State of Florida (Dec 2018) - Republic of Georgia (Sep 2016) - State of Florida (Dec 2015) - State of Pennsylvania (Apr 2012)

4. Other - National Science Centre, Government of Poland (Jan 2020) - Innovation and Technology Commission, Government of Hong Kong (Jul 2019) - Pasteur Institute of France (Apr 2019) - Health Canada’s Genomics Research and Development Initiative (GRDI) (Feb 2019) - Medical Research Council, United Kingdom (Aug 2018)

CHAIR/CO-CHAIR & MEMBER OF PLANNING COMMITTEES AT CONFERENCES AND SYMPOSIA

1. IEEE EMBS Micro & Nanotechnology in Medicine Conference, Kapolei, HI. Conference

chair (July 2019 – December 2020) 2. 2020 James W. Freston Conference “Gastrointestinal Organoids and Engineered Organ

Systems” organized by the American Gastroenterological Association. Member of Program Planning Committee (September 2019 – August 2020)

3. University of Illinois at Chicago 2nd Annual Bioengineering Research Symposium, Chicago, IL. Symposium chair (September 2019 – April 2020)

4. Annual Meeting of the Biomedical Engineering Society, Philadelphia, PA. Co-chair of track session entitled “Cell Detection” (October 2019)

5. University of Illinois at Chicago 1st Annual Bioengineering Research Symposium, Chicago, IL. Symposium chair (September 2018 – April 2019)

6. Annual Meeting of the Biomedical Engineering Society, Phoenix, AZ. Co-chair of track session entitled “Organ-on-a-Chip Models for Drug Discovery and the Study of Disease IV” (October 2017)

7. Scientific Advisor for “Tissue Engineering and Regenerative Medicine International Society Americas (TERMIS-AM)” conference (December 2016)

8. Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN. Co-chair of track session entitled “Biomaterials for Immunoengineering III” (October 2016)

9. Annual Meeting of the Biomedical Engineering Society, Minneapolis, MN. Co-chair of track session entitled “Organs-on-a-chip models for study of disease and drug discovery I” (October 2016)

10. ASME Nanoengineering for Medicine and Biology Conference (NEMB), Houston, TX. Co-chair of track entitled “Nano- and Micro-fluidics.” (February 2016)


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11. Division of Biochemical Toxicology (BIOT) Symposia of the national meeting of the American Chemical Society, Denver, CO. Invited co-chair of session entitled “Colorado Biotechnology: Biomedical Research.” (March 2015)

12. Annual Meeting of the Biomedical Engineering Society, San Antonio, TX. Co-chair of track session entitled “Hepatic, pancreatic, digestive and renal tissue engineering.” (October 2014)

13. American Meeting of the International Society for the Study of Xenobiotics, Atlanta, GA. Chair of plenary session entitled “Engineered Tissue Models for In-vitro and In-vivo Metabolism and Toxicity Testing.” (October 2011)

PARTICIPATION ON BOARDS OF JOURNALS • Editorial Board Member for journals:

o Frontiers, Biomaterials section (Jan 2020 – Present) o Scientific Reports (Feb 2019 – Present) o Experimental Biology and Medicine (Mar 2017 – Present) o Regenerative Medicine, a Nature Partner Journal (Jan 2016 – Present)

• Guest editor, Cellular and Molecular Gastroenterology and Hepatology, 2017

TEACHING EXPERIENCE (AS PRIMARY INSTRUCTOR)

At the University of Illinois at Chicago (UIC) • Quantitative Human Physiology (new graduate course developed)

- Fall 2019 (13 students). Overall instructor rating 4.38. Overall course rating 4.38 (out of 5) - Fall 2018 (9 students). Overall instructor rating 4.5. Overall course rating 4.38 (out of 5) - Fall 2017 (17 students). Overall instructor rating 4.5. Overall course rating 4.7 (out of 5) - Fall 2016 (25 students). Overall instructor rating 4.42. Overall course rating 4.0 (out of 5)

• Cell and Tissue Engineering Laboratory (revamped undergraduate course) - Spring 2019 (34 students). Overall instructor rating 4.42. Overall course rating 3.92 (out of 5) - Spring 2018 (34 students). Overall instructor rating 4.96. Overall course rating 4.89 (out of 5) - Spring 2017 (35 students). Overall instructor rating 4.80. Overall course rating 4.76 (out of 5) - Spring 2016 (36 students). Overall instructor rating 4.83. Overall course rating 4.78 (out of 5)

• Bioengineering Seminar (graduate course designed to teach scientific communication skills) - Fall 2019 (28students). Overall instructor rating 4.41. Overall course rating 4.13 (out of 5) - Fall 2018 (23students). Overall instructor rating 4.73. Overall course rating 4.44 (out of 5) - Fall 2017 (36 students). Overall instructor rating 4.18. Overall course rating 3.74 (out of 5) - Fall 2016 (39 students). Overall instructor rating 4.37. Overall course rating 3.91 (out of 5) - Fall 2015 (33 students). Overall instructor rating 4.44. Overall course rating 4.28 (out of 5)

At Colorado State University (CSU) • Quantitative Systems Physiology (new graduate course developed)

- Spring 2015 (16 students). Overall instructor rating 4.91. Overall course rating 4.54 (out of 5)


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- Spring 2014 (14 students). Overall instructor rating 4.77. Overall course rating 4.77 (out of 5) - Spring 2013 (16 students). Overall instructor rating 4.38. Overall course rating 4.21 (out of 5)

• Intro to Biomedical Engineering (new version of undergraduate course developed) - Fall 2014 (143 students). Overall instructor rating 4.91. Overall course rating 4.77 (out of 5) - Fall 2013 (112 students). Overall instructor rating 4.64. Overall course rating 4.39 (out of 5)

• Mechanics and Thermodynamics of Flow Processes (undergraduate) - Fall 2013 (17 students). Overall instructor rating 4.06. Overall course rating 4.06 (out of 5)

TEACHING EXPERIENCE (AS ASSISTANT TO INSTRUCTOR)

1. Introduction to Biomedical Engineering, CSU, Fall 2012 (apprentice under prof) 2. Mechanics and Thermodynamics of Flow Processes, CSU, Fall 2012 (apprentice under prof) 3. Head/Senior Teaching Assistant for the Department of Bioengineering at UCSD 2003-2005 4. Teaching Assistant, Biotechnology Laboratory, UCSD 2003 5. Teaching Assistant, Foundations of Tissue Engineering Science, UCSD 2002, 2003 6. Teaching Assistant, Cell and Tissue Engineering, UCSD 2002 7. Teaching Assistant, Bioengineering Physiology, UCSD 2001

POST-DOCTORAL, DOCTORAL, AND MEDICAL STUDENTS MENTORED IN RESEARCH

Research specialists (postdoctoral) 1. Cristiana Trinconi, starting July 2020 2. Yong Duk Han, Jan 2020 – Present

MD students 1. Kerim Kaylan, UIC College of Medicine, Jan 2018 – Jan 2019 PhD students 1. Nathan Calzadilla, UIC Bioengineering, Apr 2019 – Present 2. Jennifer Liu, UIC Bioengineering, May 2018 – Present 3. Yang Yuan, UIC Bioengineering, July 2017 – Present 4. Grace Brown, UIC Bioengineering, June 2017 – Present 5. David Kukla, UIC Bioengineering, June 2017 – Present 6. Regeant Panday, UIC Bioengineering, Jan 2017 – Present 7. Chase Monckton, UIC Bioengineering, Jun 2016 – Present 8. Christine Lin, CSU Biomedical Engineering, Jun 2013 – Dec 2017

- Current: Scientist I, Biopharmaceutical development at KBI BioPharma 9. Brenton Ware, CSU Biomedical Engineering, Sept 2012 – Dec 2017

- Current: Medical device analyst at Medtronic, Inc. 10. Matthew Davidson, CSU Biomedical Engineering, Jun 2012 – Dec 2016


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- Current: Postdoctoral associate at the University of Pennsylvania (Jason Burdick’s lab) 11. Kimberly Ballinger, CSU Mechanical Engineering, Sept 2014 – July 2015

- Current: Research associate at KBI BioPharma 12. Dustin Berger, CSU Biomedical Engineering, Apr 2012 – Mar 2015

- Current: Regenexx, LLC Masters students 1. Shivam Ohri, UIC Bioengineering, Mar 2019 – Present 2. Erika Ferrari, UIC Bioengineering, Aug 2017 – June 2018

- Current: PhD student at Politecnico di Milano, Milan, Italy (Rasponi lab) 3. Fabio Pradella, UIC Bioengineering, Aug 2017 – June 2018

- Current: Associate Clinical Research Specialist, Medtronic, Milan, Italy 4. Jennifer Liu, UIC Bioengineering, Dec 2016 – May 2018

- Current: PhD student in Bioengineering at UIC (Khetani lab) 5. Lioudmila Sorokina, UIC Bioengineering, May 2016 – May 2018

- Current: PhD student in Bioengineering at UIC (Shokuhfar lab) 6. Grace Brown, UIC Bioengineering, Aug 2016 – May 2017

- Current: PhD student at UIC (Khetani lab) 7. David Kukla, UIC Bioengineering, Aug 2015 – May 2017

- Current: PhD student at UIC (Khetani lab)

UNDERGRADUATE STUDENTS MENTORED IN RESEARCH

• UIC (13): Grace Brown, Hardik Dabas, Demi Ibrahim, Anupriya Mathews, Ndallah Njongmeta, Aimee Padilla, Mansi Peesapati, Tommy Puttrich, Wasinee Siewsrichol, Joshua Smejkal, Lioudmila Sorokina, Kristin Wiseman, and Berenice Zarate

• CSU (15): Joshua Pickrell, Alison Bailey, Kim Ballinger, Michael Lehrer, Connor Redalen, Olivia Smith, Aaron Paulding, Samuel Allsup, Mitch Durham, Oscar Safai-rad, Kelly Scharlau, Adam LeJeune, Jase Wyeno, Jaron Thompson, and Wendy Sunada

• M.I.T. (7): Boyla Mainsah, Julia Kiberd, Swetha Kambhampati, Jennifer Yeh, Elise Liu, Ekavali Mishra, and Sheena Bhalla

• UCSD (3): Brandon Fanelli, Ian Gaudet, Craig Sharp

PARTICIPATION IN UNIVERSITY COMMITTEES AND ACTIVITIES At the University of Illinois at Chicago (UIC) PhD thesis committees • PhD thesis committee (chair) for Regeant Panday, UIC Bioengineering, Jan 2019 - Present • PhD thesis committee (chair) for Yang Yuan, UIC Bioengineering, Jan 2019 - Present • PhD thesis committee (chair) for Grace Brown, UIC Bioengineering, Jan 2019 - Present • PhD thesis committee (chair) for Chase Monckton, UIC Bioengineering, Jan 2019 - Present


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• PhD thesis committee (chair) for Jennifer Liu, UIC Bioengineering, Jan 2019 - Present • PhD thesis committee for Adam Szmelter, UIC Bioengineering, Nov 2019 – Present • PhD thesis committee for Mounica Bandela, UIC Bioengineering, Nov 2019 – Present • PhD thesis committee for Prithviraj Mukherjee, UIC Bioengineering, Jun 2019 – Present • PhD thesis committee for Na Yoon Paik, UIC Pharmacology, Jun 2019 – Present • PhD thesis committee (chair) for David Kukla, UIC Bioengineering, Mar 2019 – Present • PhD thesis committee for Tao Teng, UIC Bioengineering, Apr 2019 – Present • PhD thesis committee for Claire Chang, UIC Bioengineering, Feb 2018 – Present • PhD thesis committee for Nickolas Anderson, UIC Bioengineering, Dec 2017 – May 2019 • PhD thesis committee for Menglin Liu, UIC Pharmacology, Aug 2018 – Mar 2019 • PhD thesis committee for Theodore Christoforidis, UIC Bioengineering, Sep 2016 – Oct 2018 • PhD thesis committee for Arghya Bishal, UIC Bioengineering, Jan 2017 – May 2018 • PhD thesis committee for Kevin Tangen, UIC Bioengineering, Apr 2017 – May 2018 • PhD thesis committee for Jason Bugno, UIC Pharmaceutical Sciences, Oct 2016 – May 2018 • PhD thesis committee for Michael Mkrtschjan, UIC Bioengineering, Apr 2016 – May 2018 • PhD thesis committee for Mahsa Ghaffari, UIC Bioengineering, Jan 2017 – April 2018 • PhD thesis committee for Megan Rexius-Hall, UIC Bioengineering, Jul 2017 – Aug 2017 • PhD thesis committee for Martin Brennan, UIC Bioengineering, Oct 2015 – May 2017 • PhD thesis committee for Hao-jui Hsu, UIC Pharmaceutical Sciences, 2016 MS thesis committees • MS thesis committee for Shivam Ohri, UIC Bioengineering, 2020 • MS thesis committee for Daniel Devine, UIC Bioengineering, 2019 • MS thesis committee for Federico Nebuloni, UIC Bioengineering, 2018 • MS thesis committee for Snehal Gaikwad, UIC Bioengineering, 2017 • MS thesis committee for Mehar Cheema, UIC Bioengineering, 2017 • MS thesis committee for Sebastian Pernal, UIC Bioengineering, 2016 • MS thesis committee for Esther Shin, UIC Bioengineering, 2016 Other committees • Medical Scientist Training Program (MSTP) Advisory Committee, UIC, July 2019 – Present • Advisor for Biomedical Engineering Society (BMES) student chapter, UIC, May 2017 – Present • Advisory Committee, UIC Department of Bioengineering, Nov 2016 – Present • Faculty advisory committee for Jae Won Shin, Dept. of Pharmacology, UIC, Apr 2016 – Present • Graduate College Awards Committee, UIC, Aug 2017 – May 2018 • Faculty search committee, UIC Bioengineering, Dec 2016 – May 2017 Continued on next page


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At Colorado State University (CSU) Graduate student committees • PhD thesis committee (chair) for Christine Lin, Biomedical Engineering, Jul 2016 – Dec 2017 • PhD thesis committee (chair) for Brenton Ware, Biomedical Engineering, Dec 2015 – Dec 2017 • PhD thesis committee (chair) for Matt Davidson, Biomedical Engineering, Jul 2015 – Dec 2016 • PhD thesis committee for Renee Lake, Biomedical Engineering, Sep 2012 – Sep 2015 • PhD thesis committee for Victoria Harcy, Cell and Molecular Biology, Sep 2012 – Jan 2014 • MS thesis committee for Stephen Gatlin, Chemistry, May 2013 – May 2014 Other committees • Mechanical Engineering Advisory Board Liaison, CSU, 2015 • Undergraduate curriculum committee (Biomedical Engineering), CSU, Sep 2012 – Sep 2015 • Ad hoc grade appeal committee, 2013 • Ad hoc biomaterials new courses committee, 2014 • Postdoctoral search committee for Civil and Environmental Engineering, 2014 • Honors thesis committee for Maria Sekyi, CBE undergraduate at CSU, 2014

K-12 EDUATIONAL OUTREACH

• Bioengineering Experience for Science Teachers (summers), University of Illinois at Chicago - 2019: Tammy Pheuphong - 2018: Jianin Shi - 2017: Kevin Connolly - 2016: John O’Brien

• Summer research experience for high school and undergraduate students - 2019: Jairaj Narendran (University of Illinois at Urbana-Champaign, IL) - 2019: Habib Rehman (Hinsdale South High School, IL) - 2017 and 2018: Shreya Viswanathan (Stevenson High School, IL) - 2014 and 2015: Benjamin Allsup (Fossil Ridge High School, CO) - 2014: Zachary Stetter (Fort Collins High School, CO) - 2013: Autumn Dern (Fort Collins High School, CO) - 2013: Ashley Brock (Fort Collins High School, CO)

• Scientific presentations at Fort Collins High School and Fossil Ridge High School (2014)

• 1st Choice After School Kare (A.S.K.) STEM learning modules for K-6 students (2013, 2014)

Documents

Salman R. Khetani, PhD - irp-cdn.multiscreensite.com · Curriculum Vitae – S.R. Khetani (Updated: January 2020) 2 Jul 2001 – Feb 2006 Graduate Research Assistant Microscale Tissue