References:1. Georgescu D, Kuo AF, Kinard KI, Olson RJ. A fluidics comparison of Alcon Infiniti, Bausch & Lomb Stellaris, and Advanced Medical

Optics Signature phacoemulsification machines. Am J Ophthalmol. 2008;145(6):1014-1017. 2. Data on file. Advanced Medical Optics Inc. 3. Antao S. KIasaby S. Comparison of ultrasound power used during phacoemulsification with and without improved control and

efficiency (ICE) software. Paper presented at: European Society for Cataract and Refractive Surgery (ESCRS) 24th Congress. 2006 Sept 9-13; London, England.

4. Fabian E, Maier M, Parasta A. New phaco fluidics control: CASE to prevent surge. Paper presented at: European Society for Cataract and Refractive Surgery (ESCRS) 24th Congress. 2006 Sept 9-13; London, England.

5. Dewey S. Whitestar® ICE: Igniting “cool phaco” to improve surgical efficiency. Paper presented at: European Society for Cataract and Refractive Surgery (ESCRS) 24th Congress. 2006 Sept 9-13; London, England.

AMO, the AMO logo, and WHITESTAR are registered trademarks and WHITESTAR Signature, Fusion, Ellips, and the Ellips logo are trademarks of Advanced Medical Optics, Inc. Bluetooth is a registered trademark of Bluetooth SIG. Infiniti is a registered trademark of Alcon Laboratories, Inc. Stellaris is a registered trademark of Bausch & Lomb, Inc.

©2008 Advanced Medical Optics, Inc., Santa Ana, CA 92705 www.amo-inc.com 2008.10.06-CT665 Reorder: PHA10-02

Part of the AMO ® Complete Refractive Solution SAfety is defined by the company you keep.

Safety iS our Signature.

Safety iS our Signature.The Revolutionary WHITESTAR Signature™ System with Fusion™ Fluidics provides surgeons with the most advanced safety features to provide the best possible outcomes for their patients.

• Proprietary Fusion™ Fluidics anticipates occlusions and preemptively adjusts the vacuum for improved chamber stability

• Distinctive Dual Pump Technology offers both venturi and peristaltic modalities in a convenient single cassette

• Exceptional Ellips™ Transversal Ultrasound provides a new alternative to torsional phaco

Award-winning Customer ServiceAMO is committed to providing outstanding technical support and

services. In recognition of this, AMO received the 2008 North Face Award for superior customer service. Our full-time, dedicated AMO Direct Field Service Representatives are qualified, experienced, and knowledgeable

and can provide surgeons with phaco expertise and support.

Experience the revolution in phaco today. Contact your AMO representative

at 1-877-AMO-4-LIFE.

PHAG-4872 Sig Brochure V10.indd 1-2 10/27/08 12:31:16 PM

SafetySAFEty Is Our Signature

Signature

Proprietary Fusion™ Fluidics • Optimizes chamber stability by anticipating occlusions and preemptively

adjusting the vacuum before the occlusion breaks in as fast as

20 milliseconds

• Provides advanced surge-protection technology, allowing high vacuum

and flow settings with any technique

• Distinctive Dual Pump Technology offers the safety of peristaltic,

the performance of venturi, and the ability to switch pumps in a

convenient, single cassette

Advanced WHITESTAR® Micropulse Technology • Exceptional Ellips™ Transversal Ultrasound combines longitudinal

and lateral motion to provide surgeons constant emulsification and

improved followability without a change in preferred technique

• Advanced pulse shaping offers preset options, plus a range of

amplitude settings for customization in each phaco setting

• Automatic occlusion sensing and power modulation for exquisite control

The WHITESTAR Signature™ System with

proprietary Fusion™ Fluidics anticipates

occlusions and preemptively adjusts the

vacuum to deliver superior chamber stability.

Surgeons can expect state-of-the-art

phacoemulsification technology designed to

deliver efficiency, convenience, and control.

PHAG-4872 Sig Brochure V10.indd 3-4 10/27/08 12:31:21 PM

Safety Proprietary dual-pump technology allows switching between peristaltic and venturi in one cassette • Utilize the peristaltic pump for deliberate and reliable performance during sculpting and

nuclear fragmentation

• Switch to the vacuum-based venturi pump for efficient irrigation/aspiration, epinuclear and corneal cleanup, and vitrectomy

• Access the flexibility of both modalities for a cost-effective and efficient tool in multi-surgeon and teaching environments

the Best of Both Worlds With Dual Pump technology

Signature

An independent, peer-reviewed study published in the American Journal of Ophthalmology shows that the WHITESTAR Signature™ System provides significantly better surge protection1

Only the WHItEStAR Signature™ System delivers up to 56% less surge than the Infiniti® System and 19% less surge than the Stellaris® System

Revolutionary Fusion™ Fluidics • Improves chamber stability by anticipating occlusions and preemptively adjusting the vacuum before the occlusion breaks

• Provides advanced surge-protection technology, allowing high vacuum and flow settings with any technique

• Reduces phaco time and increases efficiency during surgery

In an independent study measuring fluidics performance, the WHITESTAR Signature™ System delivered 56% less postocclusion surge than the Alcon Infiniti® System and 19% less than the Bausch & Lomb Stellaris® System.1

SURgE CoMPARISon CHART

When the “Up Time” has elapsed, Fusion™ Fluidics proactively steps down the vacuum to the predefined level before the occlusion breaks.2

20 milliseconds4

Vacuum (Safe Landing)

“Up Time”

Vacuum levelcrosses “UpThreshold”

“Up Threshold”

“Down Threshold”Occlusion clears uponphaco activation

By stepping down the vacuum before the occlusion breaks, Fusion™ Fluidics maintains intraocular pressure to improve chamber stability.2

CASE Chamber Stabilization Test70

60

50

40

30

20

10

0

0.0 0.5 1.0

No CASE

Full Occlusion

Intr

aocu

lar P

ress

ure

(mm

Hg)

Time (Seconds)

CASE

Occlusion Break

500 mmHg45 cc/min

FUSIon™ FlUIDICS DUAl PUMP TUbIng CASSETTE

Only the WhiteStar Signature™ System provides both peristaltic and venturi pump modalities in a convenient single cassette.

Venturi tank

Peristaltic pump

Switch control between venturi or peristaltic pump

0.5 mm

1.0 mm

1.5 mm

2.0 mmInfiniti®

1.51 ± 0.22 mm

WHITESTAR Signature™

0.67 ± 0.01 mm

Stellaris® 0.83 ± 0.06 mm

PHAG-4872 Sig Brochure V10.indd 5-6 10/27/08 12:31:28 PM

Safety

Signature

Ellips™ Transversal Ultrasound, the optimized alternative to torsional phaco, offers safe, efficient cutting• Simultaneously combines longitudinal and transversal modes for constant emulsification and minimized clogging

• Delivers enhanced magnetic followability through WHITESTAR® Micropulse Technology

• Offers efficient cutting with any tip style, bent or straight, without a change in surgeons’ preferred technique

Micropulse Technology delivers better safety, ease of use, and faster phaco times3 • Maximize ultrasound efficiency for less risk of surgical complications and better outcomes3,4

• Customize pulse shaping for enhanced magnetic followability and cavitation acceleration3,4

• Minimize endothelial cell loss and provide clearer corneas postop day one through efficient cavitation action2,3,5

Maximum Cutting Efficiency and Minimal Power With WHItEStAR® technology

Pulse shaping with preprogrammed, millisecond energy punch accelerates cavitation.2

Safe, reliable technology for efficacious procedures• Maximum cut rate of 2,500 cpm for efficient surgery

• Vitrectomy cutter options include 20 g, 23 g, and 25 g for all techniques including coaxial and sutureless pars plana

• Programmable foot pedal functionality

Advanced, High-speed Vitrectomy

User-friendly, efficient interface and accessories• Provides fast one-touch prime/tune cycle to expedite OR turnover

• Allows individual surgeon settings to be uploaded from any memory stick

• Offers cutting-edge accessories, such as LCD touchscreen monitor, wireless remote using Bluetooth® technology, and multilingual voice communication

• One-step loading tubing cassette

Built-in Innovation and Ease-of-use With the WHItEStAR Signature™ System

Intuitive touch screen

Easy-to-load tubing cassetteLightweight, ergonomic handpiece

The unique elliptical motion provides continuous cutting for optimal safety and efficiency.

PHAG-4872 Sig Brochure V10.indd 7-8 10/27/08 12:31:38 PM