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Code No: RR412301 Set No. 1
IV B.Tech I Semester Supplementary Examinations, February
2007GENOMICS AND PROTEOMICS
(Bio-Technology)Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
1. Explain in detail how life has originated. [16]
2. Explain how chromatin structure plays important role in
Eukaryotic gene regula-tion. [16]
3. Explain where are genomic variations are found. [16]
4. How could you compare genomes clustal W Alignment tool?
[16]
5. Discuss in detail how cDNA is prepared. [16]
6. What do you mean by biochipnology. Discuss? [16]
7. Write short notes:
(a) Human Metabolome
(b) Functional Genomics. [8+8]
8. What is the role of ELSI in research programs? [16]
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Code No: RR412301 Set No. 2
IV B.Tech I Semester Supplementary Examinations, February
2007GENOMICS AND PROTEOMICS
(Bio-Technology)Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
1. Discuss in detail about biodiversity. [16]
2. Discuss in detail about Lactose operon. [16]
3. Discuss in detail about repetitive DNA. [16]
4. How could you evaluategene prediction Engines? [16]
5. Write short notes:
(a) Protein sequence data
(b) Sequence database search. [8+8]
6. Write short notes:
(a) Biochips
(b) Micro arrays. [8+8]
7. How SNP plays an important role in identifying disease gene?
[16]
8. How could you explain drug design using known receptor
structures? [16]
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8/14/2019 Rr412301 Genomics and Proteomics
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Code No: RR412301 Set No. 3
IV B.Tech I Semester Supplementary Examinations, February
2007GENOMICS AND PROTEOMICS
(Bio-Technology)Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
1. Write short notes
(a) 5 caping in mRNA
(b) 3 Poly A Tailing in mRNA [8+8]
2. wirte short notes
(a) Histone proteins
(b) Chromatin [8+8]
3. Expalin in detail about mobile DNA and its classification.
[16]
4. Write short notes:
(a) Comparative genomics
(b) Functional genomics. [8+8]
5. How could you find genes by searching the proteins sequence
database? [16]
6. What do you mean by biochipnology. Discuss? [16]7. Explain
how SNPs are usefull to find disease genes. [16]
8. How could you explain drug design using known receptor
structures? [16]
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Code No: RR412301 Set No. 4
IV B.Tech I Semester Supplementary Examinations, February
2007GENOMICS AND PROTEOMICS
(Bio-Technology)Time: 3 hours Max Marks: 80
Answer any FIVE Questions
All Questions carry equal marks
1. Write short notes:
(a) DNA lagging strand synthesis
(b) Enzymes involved in DNA replication. [8+8]
2. Discuss in detail about Lactose operon. [16]
3. Explain kinetics of DNA renaturation. [16]
4. How could you compare genomes clustal W Alignment tool?
[16]
5. Discuss in detail about homology modeling and drug design.
[16]
6. Explain how disease genes can be identified by proteomics.
[16]
7. How EST library plays an important role in identifying
disease gene? [16]
8. Explain the metabolism of drug. [16]
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