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    Abstract

    Diabetes is one disease that doesnt need any introduction to modern day people.

    Moreover, effect of microwave radiation on our body is one area that much of the modern

    day research is focused on. This study focuses on the effects that this two problems have

    on the brain, an area of huge interest for neuroscientists. Our study uses rats as the animal

    model for this experiment. The work has been carried out on four groups of rats i) control

    group which acts as a reference ii) diabetic rats iii) microwave irradiated rats iii) diabetic

    rats exposed to microwave radiation. The rats were made diabetic by injecting a chemical

    Streptozotocin i.p. The microwave radiation of 2.45 GHz was given to the rats with the

    help of a Microwave Analog Signal Generator. The effects produced on rat brain was

    analyzed by recording the brain electrical potential called Electroencephalography (EEG)with the help of R.M.S provided Polyrite machine. The signal processing toolbox of

    Matlab is used profoundly for processing the signal and performing spectral analysis of it

    mention results. The results have showed increase in slow waves activity especially Delta

    waves of EEG in all the groups with maximum effect on diabetic rats exposed to

    microwave radiation.

    Keywords: Microwave radiation, Diabetes, EEG, spectral analysis.

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    List of figures

    Fig 1.1: Healthy EEG waveform 3

    Fig 1.2: EEG Power spectrum of a healthy patient 4

    Fig 2.1: (a) Overall process of Type 2 Diabetes 9

    (b) Insulin Resistance created in Type 2 Diabetes 9

    Fig 2.2: Harmful effects of Diabetes 11

    Fig 3.1: Rats in their animal holder 36

    Fig 3.2: Experimental Setup for microwave exposure 37

    Fig 3.3: Electrodes implanted at different positions of rat brain 38

    Fig 3.4: Total EEG Setup 38

    Fig 4.1: Power Spectral Density of frontoparietal channel by Welch Method 44

    Fig 4.2: Power Spectral Density of frontoparietal channel by AR Method 45

    Fig 4.3: Power Spectral Density of occipital channel by Welch Method 46

    Fig 4.4: Power Spectral Density of occipital channel by AR Method 47

    Fig 4.5: Power Spectral Density of Temporal channel by Welch Method 48

    Fig 4.6: Power Spectral Density of temporal channel by AR Method 49

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    Fig 4.7: Mean power of frequency bands in frontoparietal channel by Welch method 50

    Fig 4.8: Mean power of frequency bands in frontoparietal channel by AR method 50

    Fig 4.9: Mean power of frequency bands in occipital channel by Welch method 51

    Fig 4.10: Mean power of frequency bands in occipital channel by AR method 51

    Fig 4.11: Mean power of frequency bands in temporal channel by Welch method 52

    Fig 4.12: Mean power of frequency bands in temporal channel by AR method 52

    Fig 4.13: Mean power of different channels by Welch method 53

    Fig 4.13: Mean power of different channels by AR method 53

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    List of Tables

    Table 2.1: Different Microwave Bands 15

    Table 2.2: EEG frequency bands 24

    Table 3.1: Flowchart of EEG signal processing 39

    Table 4.1: Blood Glucose level measures on Day 0 and Day 3 42

    Table 4.2: Body weights of Rat 1 and Rat 2 43

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    List of Abbreviations

    CNS Central Nervous System

    PNS Peripheral Nervous System

    EEG Electroencephalography

    GHz Gega Hertz

    KHz Kilo Hertz

    PSD Power Spectral Density

    AR Auto Regressive

    A/m Ampere per meter

    V/m Volt per meter

    IEEE Institute of Electrical and Electronics

    Engineers

    RF Radiofrequency

    ISM Industrial Scientific and Medical

    applications

    SAR Specific Absorption rate

    DNA Deoxyribonucleic Acid

    PW Pulsed Wave

    CW Continuous Wave

    mW milliwatt

    W microwatt

    J/g Joule per gram

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    C.S.F Cerebro Spinal Fluid

    cl Chlorine

    K Potassium

    ECG Electroencephalography

    PPP Post Synaptic Potential

    FFT Fast Fourier Transform

    gm Gram

    i.p. Intraperitoneal

    STZ Streptozotocin

    dB Decibel

    dBm Decibel to 1 milliwatt

    mm/min Millimeter per minute

    Fs Sampling frequency

    mg/dl Milligram per deciliter

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