RNA & Central Dogma

BELLWORK- HAVE SLATE, MARKER & ERASER ON DESK

1. What does DNA stand for?

2. Based on your answer to #1, predict what RNA stands for?

3. What is the complementary DNA strand to this sequence GTA ATC ATA?

4. Draw and label a picture of a nucleotide.

5. Who are Watson & Crick & what do they have to do with DNA?

Announcements

Bio 1-2: Is your science fair board turned in?

PreAP: BLAST handout get ratHBB from class website @ home DietrichBiology.wikispaces.com due date changed to next Tues. 1-28-14

Everyone: This is a block week, so Friday is….

Everyone: Pass out slates for today

Central Dogma (“Big Idea”) of Biology

DNA

RNA

Protein

DNA stores information to run cell

DNA vs RNA

Deoxyribonucleic Acid

•How many nucleotides?

•3 parts of a nucleotide?

•What does the “B” stand for?

DNA vs RNA

Deoxyribonucleic Acid

•How many nucleotides?

•3 parts of a nucleotide?

•What does the “B” stand for?

Ribonucleic Acid

What’s the

difference?

OH!

Remember this?

Structure is related

to function!

What are DNA’s 2 functions?

RNA Structure Notes

•RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)

RNA Structure Notes

•RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)

•In RNA, the nitrogenous bases are G,C,A and U (no T)

RNA Structure Notes

•RIBOSE is the sugar in RNA nucleotides (instead of deoxyribose)

•In RNA, the nitrogenous bases are G,C,A and U (no T)

•RNA is usually single-stranded

Vote by sign language:

DNADNA

AGCCTGCTATCGGACGAT

RNA

RNA RNA

NA NA

Try this

What might it look like if you turned this double stranded DNA molecule into an RNA copy?

AGTTCGATCAAGCT

RNA: UCAAGCUWhich DNA strand would this RNA be the COMPLEMENT of?

Try this

What might it look like if you turned this double stranded DNA molecule into an RNA copy?

AGTTCGATCAAGCT

RNA: UCAAGCUWhich DNA strand would this RNA be the COMPLEMENT of?

Do the RNA complement for the bottom DNA strand

AGUUCGA

DNA vs RNA

RNA has a

different structure

… predict

it’s functions (jobs)

Hint: other names for RNA

messenger RNA

ribosomal RNA

transfer RNA

Central Dogma (“Big Idea”) of Biology

DNA

RNA

Protein

DNA stores information to run cell

RNA’s function is

to make proteins!

Why are proteins so important? Proteins are made of tiny subunits…what

are they called?

What are some functions of proteins? (Hint: ) Chemical Reactions (enzymes) Immune System (antibodies) Growth & Development (hormones) etc.

Central Dogma (“Big Idea”) of Biology

DNA

RNA

Protein

DNA stores information to run cell

Proteins actually DO the work in

the cell

RNA’s function is

to make proteins!

Types of RNA

mRNA: messenger RNA makes a copy (message) of the information stored in DNA & moves the info out of the nucleus! (DNA doesn’t leave nucleus)

Codons are 3 letter “words” that make up the message- it’s a recipe for a protein

Types of RNA

rRNA: ribosomal RNA folds into a ribosome which reads the mRNA codons and connects amino acids into a chain that will become a proteinrRNA folds into 2

subunits (large & small)

Together, they make the ribosome!

Realistic image of rRNA folded

into a ribosome

Types of RNA

tRNA: transfer RNA transports amino acids to the ribosome, and uses an anti-codon to match the correct amino acid to the correct mRNA codon. It then transfers amino acids to the growing chain.tRNA is

T-shaped!

Closure- Structure & Function of DNA & RNA

DNA

RNA