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How Does Each Active Ingredient Function in this Product? Ribose *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. For more information visit www.jarrow.com Improves endurance and recovery during intense training* D-Ribose is a simple carbohydrate and a building block for energy carriers, cell signaling molecules and nucleic acids.* Other Ingredients Powder: 100% D-Ribose. Contains NO other substances. No wheat, no gluten, no soy, no dairy, no egg, no fish/shellfish, no nuts/tree nuts. Chewable: Xylitol, raspberry flavor, modified cellulose, stearic acid (vegetable source), magnesium stearate (vegetable source), and silicon dioxide. Suggested Usage Powder: A 1/4 teaspoonful supplies 1000 mg of pure D-ribose. Athletes should take 1-5 grams before and/or after exercise on an empty stomach or as directed by a qualified health consultant. Chewable: Chew 1 to 6 tablets before or after exercise, or as directed by your qualified health care consultant. Note Ribose has been supplemented at up to 60 grams per day without side effects. However, single servings of 20 grams or more may cause diarrhea and are not recommended. Who Can Benefit from this Product? Jarrow Formulas ® Ribose is for athletes and others interested in improved levels of energy, endurance and recovery.* What Distinguishes this Product? • Jarrow Formulas Ribose Muscle Edge ® is made by microbial fermentation and protected by four U.S. patents. • Jarrow Formulas Ribose is highly purified, consisting solely of D-ribose. ORDERING INFORMATION ORDER CODE: RIBPD BOTTLE SIZE: 100 GRAMS POWDER ORDER CODE: RIB200 BOTTLE SIZE: 200 GRAMS POWDER ORDER CODE: RIB90 BOTTLE SIZE: 90 CHEW TABLETS Athletic Formulas PRODUCT CATEGORY D-Ribose The limiting factor in the production of energy carriers. It increases energy and endurance, supports muscle recovery, and is synergistic with creatine.* healthy living through science & education QUICK Reference Guide Jarrow FORMULAS ® Supplement Facts Serving Size 1/2 Teaspoon or 1 Scoop (approx 2 gm) Amount Per Serving % DV Calories 9 Total Carbohydrate 2.2 g <1% Sugars 2.2 g D-Ribose 2200 mg * † Daily value not established. * Need in human nutrition not established. Powder Products Supplement Facts Serving Size 1 Tablet Servings Per Container 90 Amount Per Serving % DV Calories 14 Total Carbohydrate 1 .5 g <1% Sugars 1 g D-Ribose 1 g * † Daily value not established. * Need in human nutrition not established. Chewable Product 0908RIBOSE

Ribose - Jarrow FormulasCreatine, a popular supplement for athletes, helps muscles quickly replenish ATP during intense exercise.* The Ribose Links to Energy Under extreme stress,

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Page 1: Ribose - Jarrow FormulasCreatine, a popular supplement for athletes, helps muscles quickly replenish ATP during intense exercise.* The Ribose Links to Energy Under extreme stress,

How Does Each Active Ingredient Function in this Product?

Ribose

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

For more information visit www.jarrow.com

Improves endurance and recovery during intense training*

D-Ribose is a simple carbohydrate and a building block for energy carriers, cell signaling molecules and nucleic acids.*

Other IngredientsPowder: 100% D-Ribose. Contains NO other substances. No wheat, no gluten, no soy, no dairy, no egg, no fish/shellfish, no nuts/tree nuts. Chewable: Xylitol, raspberry flavor, modified cellulose, stearic acid (vegetable source), magnesium stearate (vegetable source), and silicon dioxide.

Suggested UsagePowder: A 1/4 teaspoonful supplies 1000 mg of pure D-ribose. Athletes should take 1-5 grams before and/or after exercise on an empty stomach or as directed by a qualified health consultant.

Chewable: Chew 1 to 6 tablets before or after exercise, or as directed by your qualified health care consultant.

NoteRibose has been supplemented at up to 60 grams per day without side effects. However, single servings of 20 grams or more may cause diarrhea and are not recommended.

Who Can Benefit from this Product?Jarrow Formulas® Ribose is for athletes and others interested in improved levels of energy, endurance and recovery.*

What Distinguishes this Product?• Jarrow Formulas Ribose Muscle Edge® is made by microbial

fermentation and protected by four U.S. patents.

• Jarrow Formulas Ribose is highly purified, consisting solely of D-ribose.

ORDERING INFORMATIONORDER CODE: RIBPD BOTTLE SIZE: 100 GRAMS POWDER ORDER CODE: RIB200 BOTTLE SIZE: 200 GRAMS POWDERORDER CODE: RIB90 BOTTLE SIZE: 90 CHEW TABLETS

Athletic FormulasP R O D U C T C A T E G O R Y

D-RiboseThe limiting factor in the production of energy carriers. It increases energy and endurance, supports muscle recovery, and is synergistic with creatine.*

h e a l t h y l i v i n g t h r o u g h s c i e n c e & e d u c a t i o nQUICKReference Guide Jarrow

F O R M U L A S®

Supplement FactsServing Size 1/2 Teaspoon or 1 Scoop (approx 2 gm)

Amount Per Serving % DVCalories 9Total Carbohydrate 2.2 g <1% Sugars 2.2 g †D-Ribose 2200 mg *† Daily value not established.* Need in human nutrition not established.

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Supplement FactsServing Size 1 TabletServings Per Container 90

Amount Per Serving % DVCalories 14Total Carbohydrate 1 .5 g <1% Sugars 1 g †D-Ribose 1 g *

† Daily value not established.* Need in human nutrition not established.

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0908RIBOSE

Page 2: Ribose - Jarrow FormulasCreatine, a popular supplement for athletes, helps muscles quickly replenish ATP during intense exercise.* The Ribose Links to Energy Under extreme stress,

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

For more information visit www.jarrow.com

Ribose ProductsA Dynamic CarbohydrateJarrow Formulas® Ribose (100% D-ribose) is for athletes and others interested in improved energy, endurance and recovery.* Ribose is a carbohydrate found in every cell in the body. It is an important component of DNA and RNA, structures that make up our genes. Ribose is also involved in ATP production, the body’s main energy source.*

Research since the 1970s has continued to confirm the benefit of this compound for the heart and circulation, and recently for energy metabolism in skeletal muscles.*

Energy Production by the CellsATP (adenosine triphosphate) contains ribose, adenine plus three phosphate groups. Energy transfer involves the linking and unlinking of these phosphate groups. Thus, ATP provides energy when it loses a phosphate group to become ADP (adenosine diphosphate), or when it loses two phosphates to become AMP (adenosine monophosphate). Eventually, phosphate groups are added back to AMP and ADP to replenish ATP. Creatine, a popular supplement for athletes, helps muscles quickly replenish ATP during intense exercise.*

The Ribose Links to EnergyUnder extreme stress, or in certain disease states, phosphate groups do not reattach to form ATP, and ADP is further broken down into AMP. The build-up of AMP in cells is not a stable condition, so some AMP is removed, resulting in the loss of adenine and ribose. Loss of these components in cells makes it harder for the body to store and transfer energy.*

Ribose is the limiting factor in the production of energy carriers. Cells cannot absorb ATP from blood, so each must make its own ATP. At any one time, enough ATP is stored in the body for about 10 seconds of all-out exertion –– so it is imperative to keep the ADP-to-ATP energy cycle flowing smoothly. The more active the muscle, the more ATP it uses. During intense exertion, skeletal muscles quickly exhaust their ATP stores, and heart muscle is most vulnerable to ATP shortages. These muscles can therefore benefit from ribose supplementation.*

Ribose Improves Muscle Energy and RecoveryIt should be noted that ribose is not readily available in amounts near recommended quantities from any food source. The body must make ribose from glucose through a series of complicated and energy-intensive steps. Unfortunately, this process is quite slow and may actually require days to complete. Supplemental ribose, in contrast, is immediately available to the body.*

The body uses ribose energetically in three ways: 1) Ribose can be used to produce glucose and glycogen (the

storage form of carbohydrate energy). While offering the energy benefits of sugars, ribose does not affect blood sugar levels.*

2) When oxygen is available, ribose can be converted into pyruvate, another energy source.*

3) Most importantly, ribose is necessary for the ATP production. Without ribose, cells cannot provide energy. With ribose, cells can recover rapidly from intense exertion.*

Research has shown that intense exercise causes significant ATP decreases in skeletal muscle. These energy carriers were not fully replaced even after 72 hours of rest. This may be an important consideration in overexertion and in over-training. Research presented at the American College of Sports Medicine meeting in 1999 indicates that ribose supplemention may greatly reduce recovery time after intense exertion. Indeed, ribose is the immediate precursor to PRPP (5-phosphoribosyl-1-pyrophosphate), which is the rate-limiting factor in ATP synthesis. For athletes, this is of major importance. The synthesis of the adenine/ribose component of ATP is 3-6 times faster with ribose supplementation!*

• Dynamic Simple Carbohydrate*• Increases Energy and Endurance*• Synergistic with Creatine*• Supports Muscle Recovery*

Jarrow Formulas Ribose Muscle Edge® is made by microbial fermentation. Protected by U.S. patents 6,159,942, 6,534,480, 6,218,366, and 6,339,716.

ReferencesAvailable upon request

h e a l t h y l i v i n g t h r o u g h s c i e n c e & e d u c a t i o nQUICKReference Guide Jarrow

F O R M U L A S®