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Review of Chi Square Richard L. Amdur, PhD Chief, Biostatistics, DCVAMC Slides are saved in T:\Biostat

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Review of Chi Square. Richard L. Amdur, PhD Chief, Biostatistics, DCVAMC. Slides are saved in T:\Biostat. region x response. region response Frequency| Percent | - PowerPoint PPT Presentation

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Page 1: Review of Chi Square

Review of Chi Square

Richard L. Amdur, PhDChief, Biostatistics, DCVAMC

Slides are saved in T:\Biostat

Page 2: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 10.00 | 23.33 | 33.33 | 30.00 | 70.00 | | 27.91 | 36.36 | ---------+--------+--------+ B | 70 | 130 | 200 | 11.67 | 21.67 | 33.33 | 35.00 | 65.00 | | 32.56 | 33.77 | ---------+--------+--------+ C | 85 | 115 | 200 | 14.17 | 19.17 | 33.33 | 42.50 | 57.50 | | 39.53 | 29.87 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00

Statistic DF Value Prob------------------------------------------------------Chi-Square 2 6.8861 0.0320Phi Coefficient 0.1071

region x response

Page 3: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 10.00 | 23.33 | 33.33 | 30.00 | 70.00 | | 27.91 | 36.36 | ---------+--------+--------+ B | 70 | 130 | 200 | 11.67 | 21.67 | 33.33 | 35.00 | 65.00 | | 32.56 | 33.77 | ---------+--------+--------+ C | 85 | 115 | 200 | 14.17 | 19.17 | 33.33 | 42.50 | 57.50 | | 39.53 | 29.87 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00

Statistic DF Value Prob------------------------------------------------------Chi-Square 2 6.8861 0.0320Phi Coefficient 0.1071

region x response

Page 4: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 10.00 | 23.33 | 33.33 | 30.00 | 70.00 | | 27.91 | 36.36 | ---------+--------+--------+ B | 70 | 130 | 200 | 11.67 | 21.67 | 33.33 | 35.00 | 65.00 | | 32.56 | 33.77 | ---------+--------+--------+ C | 85 | 115 | 200 | 14.17 | 19.17 | 33.33 | 42.50 | 57.50 | | 39.53 | 29.87 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00

Statistic DF Value Prob------------------------------------------------------Chi-Square 2 6.8861 0.0320Phi Coefficient 0.1071

region x response

Page 5: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 10.00 | 23.33 | 33.33 | 30.00 | 70.00 | | 27.91 | 36.36 | ---------+--------+--------+ B | 70 | 130 | 200 | 11.67 | 21.67 | 33.33 | 35.00 | 65.00 | | 32.56 | 33.77 | ---------+--------+--------+ C | 85 | 115 | 200 | 14.17 | 19.17 | 33.33 | 42.50 | 57.50 | | 39.53 | 29.87 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00

Statistic DF Value Prob------------------------------------------------------Chi-Square 2 6.8861 0.0320Phi Coefficient 0.1071

region x response

Page 6: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 10.00 | 23.33 | 33.33 | 30.00 | 70.00 | | 27.91 | 36.36 | ---------+--------+--------+ B | 70 | 130 | 200 | 11.67 | 21.67 | 33.33 | 35.00 | 65.00 | | 32.56 | 33.77 | ---------+--------+--------+ C | 85 | 115 | 200 | 14.17 | 19.17 | 33.33 | 42.50 | 57.50 | | 39.53 | 29.87 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00

Statistic DF Value Prob------------------------------------------------------Chi-Square 2 6.8861 0.0320Phi Coefficient 0.1071

region x response

Page 7: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 15.00 | 35.00 | 50.00 | 30.00 | 70.00 | | 46.15 | 51.85 | ---------+--------+--------+ B | 70 | 130 | 200 | 17.50 | 32.50 | 50.00 | 35.00 | 65.00 | | 53.85 | 48.15 | ---------+--------+--------+ Total 130 270 400 32.50 67.50 100.00 Statistic DF Value Prob ------------------------------------------------------ Chi-Square 1 1.1396 0.2857

Phi Coefficient -0.0534

Region (A vs. B) x response

Page 8: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ B | 70 | 130 | 200 | 17.50 | 32.50 | 50.00 | 35.00 | 65.00 | | 45.16 | 53.06 | ---------+--------+--------+ C | 85 | 115 | 200 | 21.25 | 28.75 | 50.00 | 42.50 | 57.50 | | 54.84 | 46.94 | ---------+--------+--------+ Total 155 245 400 38.75 61.25 100.00 Statistic DF Value Prob ------------------------------------------------------ Chi-Square 1 2.3700 0.1237

Phi Coefficient -0.0770

Region (B vs. C) x response

Page 9: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 15.00 | 35.00 | 50.00 | 30.00 | 70.00 | | 41.38 | 54.90 | ---------+--------+--------+ C | 85 | 115 | 200 | 21.25 | 28.75 | 50.00 | 42.50 | 57.50 | | 58.62 | 45.10 | ---------+--------+--------+ Total 145 255 400 36.25 63.75 100.00 Statistic DF Value Prob ------------------------------------------------------ Chi-Square 1 6.7613 0.0093

Phi Coefficient -0.1300

Region (A vs. C) x response

Page 10: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A | 60 | 140 | 200 | 10.00 | 23.33 | 33.33 | 30.00 | 70.00 | | 27.91 | 36.36 | ---------+--------+--------+ B+C | 155 | 245 | 400 | 25.83 | 40.83 | 66.67 | 38.75 | 61.25 | | 72.09 | 63.64 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00 Statistic DF Value Prob ------------------------------------------------------ Chi-Square 1 4.4397 0.0351

Phi Coefficient -0.0860

Region (A vs. B+C) x response

Page 11: Review of Chi Square

region response Frequency| Percent | Row Pct | Col Pct |No |Yes | Total ---------+--------+--------+ A+B | 130 | 270 | 400 | 21.67 | 45.00 | 66.67 | 32.50 | 67.50 | | 60.47 | 70.13 | ---------+--------+--------+ C | 85 | 115 | 200 | 14.17 | 19.17 | 33.33 | 42.50 | 57.50 | | 39.53 | 29.87 | ---------+--------+--------+ Total 215 385 600 35.83 64.17 100.00 Statistic DF Value Prob ------------------------------------------------------ Chi-Square 1 5.7989 0.0160

Phi Coefficient -0.0983

Region (A+B vs. C) x response

Page 12: Review of Chi Square

Number of subjects responding Yes or No in each region

response

region | No | Yes | Total----------+------+--------+--------A+B | 130 | 270 | 400----------+------+--------+--------C | 85 | 115 | 200----------+------+--------+--------Total 215 385 600

Odds Ratio for a Yes Response in Region C

OR (C=yes) = (115/85)/(270/130) = 0.65

95% Confidence interval is 0.46 – 0.92

The odds of saying “yes” are 35% lower in C than in the other regions.

The Relative Risk of saying “yes” in Region C is 0.85, compared to Regions A&B

[RR = (115/200)/(270/400)

Page 13: Review of Chi Square

Response

Region N Y Total % yesOR vs

Region C

A 60 140 200 70% a 1.72

B 70 130 200 65% a,b 1.37

C 85 115 200 58% b reference

Total 215 385 600 64%  

For % yes, rows that do not share a superscipt are significantly different (p<.05).

Page 14: Review of Chi Square

How to compute a 2x2 chi-squarehttp://graphpad.com/quickcalcs/contingency1.cfm

Page 15: Review of Chi Square
Page 16: Review of Chi Square

When there are more than 2 rows or columns:

r×c Contingency Table: How many rows? columns?

You are about to enter your data for a chi-square contingency table analysis. For this to make sense you should have a table of data (at least 2x2; maximum: 9x9).

Number of rows:

Number of columns:

You must have data for each box in the table: no blanks allowed!

http://www.physics.csbsju.edu/stats/contingency_NROW_NCOLUMN_form.html

3

2

Submit

Page 17: Review of Chi Square

Data Entry: 3 × 2 Contingency Table

Your data have been doubly sorted into one of the 2 "treatments" (A, B, ...) and into one of the 3 "outcomes" (1, 2, ...). In the below table you are to enter the number of data items that fit into a particular (treatment,outcome) pair e.g., (B1 or A2). Enter your data in the below set of boxes and then click on the Calculate Now button when data entry is complete. Leave no empty boxes! All entries should be whole numbers!

123

A B

Calculate Now Clear All

Page 18: Review of Chi Square

r × c Contingency Table: Results

The results of a contingency table X2 statistical test performed at 12:53 on 19-DEC-2010

data: contingency table A B 1 60 140 200 2 70 130 200 3 85 115 200

215 385 600

expected: contingency table A B

4 71.7 128. 5 71.7 128. 3 71.7 128.

chi-square = 6.89 degrees of freedom = 2probability = 0.032