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 RD-  RD- Teaching Aids: NNF 1 1 Respiratory distress Respiratory distress Cause of significant morbidity and Cause of significant morbidity and mortality mortality Incidence 4 to 6% of live births Incidence 4 to 6% of live births Many are preventable Many are preventable Early recognition timely referral Early recognition timely referral appropriate treatment essential appropriate treatment essential  !!! "similima"com !!!"similima"com

Respiratory Distress Children

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 RD- RD-Teaching Aids: NNF  11

Respiratory distressRespiratory distress

• Cause of significant morbidity andCause of significant morbidity and

mortalitymortality

• Incidence 4 to 6% of live birthsIncidence 4 to 6% of live births

• Many are preventableMany are preventable

• Early recognition timely referralEarly recognition timely referralappropriate treatment essentialappropriate treatment essential

 !!!"similima"com!!!"similima"com

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 RD- RD-Teaching Aids: NNF  ##

 Respiratory distressRespiratory distress

• RR $ 6& minRR $ 6& min''

RetractionsRetractions• (runt(runt

• )) CyanosisCyanosis

' *achypnea' *achypnea

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 RD- RD-Teaching Aids: NNF  ++

  Causes of respiratory distressCauses of respiratory distress

• ,ulmonary,ulmonary

• Cardiac- Congenital heart diseaseCardiac- Congenital heart disease

• C./- 0sphyia IC bleedC./- 0sphyia IC bleed

• Metabolic-2ypoglycemia acidosisMetabolic-2ypoglycemia acidosis

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 RD- RD-Teaching Aids: NNF  44

Causes of respiratory distress - MedicalCauses of respiratory distress - Medical

• Respiratory distress syndrome 3R/5Respiratory distress syndrome 3R/5

Meconium aspiration syndrome 3M0/5Meconium aspiration syndrome 3M0/5• *ransient tachypnoea of ne!born 3**.5*ransient tachypnoea of ne!born 3**.5

•  0sphyial lung disease 0sphyial lung disease

• ,neumonia- Congenital aspiration nosocomial,neumonia- Congenital aspiration nosocomial

• ,ersistent pulmonary hypertension 3,,2.5,ersistent pulmonary hypertension 3,,2.5

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 RD- RD-Teaching Aids: NNF  77

/urgical causes of respiratory distress/urgical causes of respiratory distress

• *racheo-esophageal fistula*racheo-esophageal fistula

• iaphragmatic herniaiaphragmatic hernia

• 8obar emphysema8obar emphysema

• ,ierre -Robin syndrome,ierre -Robin syndrome

• Choanal atresiaChoanal atresia

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 RD- RD-Teaching Aids: NNF  66

 0pproach to respiratory distress 0pproach to respiratory distress

HistoryHistory

• 9nset of distress9nset of distress

• (estation(estation

•  0ntenatal steroids 0ntenatal steroids

,redisposing factors- ,R9M fever ,redisposing factors- ,R9M fever • Meconium stained amniotic fluidMeconium stained amniotic fluid

•  0sphyia 0sphyia

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 RD- RD-Teaching Aids: NNF  ::

 0pproach to respiratory distress 0pproach to respiratory distress

ExaminationExamination

• /everity of respiratory distress/everity of respiratory distress

.eurological status.eurological status• lood pressure C;*lood pressure C;*

• 2epatomegaly2epatomegaly

• CyanosisCyanosis• ;eatures of sepsis;eatures of sepsis

• 8oo< for malformations8oo< for malformations

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 RD- RD-Teaching Aids: NNF  ==

 0ssessment of respiratory distress 0ssessment of respiratory distress

/core '/core '       1 #  1 #

1"1" Resp" rateResp" rate   >6  >6   6-=  6-=   $=  $=

#"#" CentralCentral .one  .one   .one !ith .eeds.one !ith .eedscyanosiscyanosis  40%40% ;i9;i922 >>4% ;i94% ;i922

1"1" Retractions .oneRetractions .one   Mild  Mild   /evere  /evere

#"#" (runting(runting   .one Minimal  .one Minimal   9bvious  9bvious

+"+"  0ir entry 0ir entry   (ood  (ood   ecreased  ecreased   ?ery poor   ?ery poor 

' /core $ 6 indicates severe distress' /core $ 6 indicates severe distress

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 RD- RD-Teaching Aids: NNF  @@

 0pproach to respiratory distress 0pproach to respiratory distress

Chest examinationChest examination

•  0ir entry 0ir entry

• Mediastinal shiftMediastinal shift

•  0dventitious sounds 0dventitious sounds

• 2yperinflation2yperinflation

• 2eart sounds2eart sounds

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 RD- RD-Teaching Aids: NNF  11

,reterm - ,ossible etiology,reterm - ,ossible etiology

Early progressive -Early progressive - Respiratory distressRespiratory distress

  syndrome or hyalinesyndrome or hyaline

membrane diseasemembrane disease32M532M5

Early transient -Early transient -  0sphyia metabolic 0sphyia metabolic

causes hypothermiacauses hypothermia

 0nytime - ,neumonia 0nytime - ,neumonia

 

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 RD- RD-Teaching Aids: NNF  1111

*erm A ,ossible etiology*erm A ,ossible etiology

Early !ell loo<ingEarly !ell loo<ing  -- **.**. ppolycythemiaolycythemia

Early severe distressEarly severe distress - M0/ asphyia- M0/ asphyia

malformationsmalformations

8ate sic< !ith - Cardiac8ate sic< !ith - Cardiac

  hepatomegalyhepatomegaly

8ate sic< !ith shoc<8ate sic< !ith shoc< - 0cidosis  - 0cidosis

 0nytime 0nytime - ,neumonia- ,neumonia

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 RD- RD-Teaching Aids: NNF  1#1#

/uspect surgical cause/uspect surgical cause

• 9bvious malformation9bvious malformation

• /caphoid abdomen/caphoid abdomen

• ;rothing;rothing

• 2istory of aspiration2istory of aspiration

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 RD- RD-Teaching Aids: NNF  1+1+

InvestigationsInvestigations

• (astric aspirate(astric aspirate

• ,olymorph count,olymorph count• /epsis screen/epsis screen

• Chest B-rayChest B-ray

• lood gas analysislood gas analysis

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 RD- RD-Teaching Aids: NNF  1414

/ha<e test/ha<e test

• *a<e a test tube

•  Mi "7 ml gastric aspirate )

"7 ml absolute alcohol

• /ha<e for 17 seconds

•  0llo! to stand 17 minutes forinterpretation of result

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 RD- RD-Teaching Aids: NNF  1717

Respiratory distress -Respiratory distress -

ManagementManagement

• MonitoringMonitoring

• /upportive/upportive

-- I? fluidI? fluid

- Maintain vital signs- Maintain vital signs

- 9ygen therapy- 9ygen therapy

- Respiratory support- Respiratory support

• /pecific/pecific

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 RD- RD-Teaching Aids: NNF  1616

9ygen therapy'9ygen therapy'

  IndicationsIndications

•  0ll babies !ith distress 0ll babies !ith distress

• CyanosisCyanosis

• ,ulse oimetry /a9,ulse oimetry /a922 << @%@%

MethodMethod

• ;lo! rate #-7 8& min;lo! rate #-7 8& min

• 2umidified oygen by hood or nasal prongs2umidified oygen by hood or nasal prongs

 ' Cautious administration in pre-term' Cautious administration in pre-term

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 RD- RD-Teaching Aids: NNF  1:1:

,ulse oimetry,ulse oimetry

• Effective non invasive monitoring ofEffective non invasive monitoring of

oygen therapyoygen therapy

• Ideally must for all sic< neonates andIdeally must for all sic< neonates and

those reuiring oygen therapythose reuiring oygen therapy

• Maintain /a9Maintain /a9## bet!een @ A @+ %bet!een @ A @+ %

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 RD- RD-Teaching Aids: NNF  1=1=

Respiratory distress syndrome 3R/5Respiratory distress syndrome 3R/5

• ,re-term baby,re-term baby

• Early onset !ithin 6 hoursEarly onset !ithin 6 hours

• /upportive evidenceD .egative sha<e test/upportive evidenceD .egative sha<e test

• Radiological evidenceRadiological evidence

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 RD- RD-Teaching Aids: NNF  1@1@

B-ray - R/B-ray - R/

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 RD- RD-Teaching Aids: NNF  ##

,athogenesis of R/,athogenesis of R/

• ecreased or abnormal surfactantecreased or abnormal surfactant

•  0lveolar collapse 0lveolar collapse

• Impaired gas echangeImpaired gas echange

• Respiratory failureRespiratory failure

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 RD- RD-Teaching Aids: NNF  #1#1

R/ - ,redisposing factorsR/ - ,redisposing factors

• ,rematurity,rematurity

• Cesarean bornCesarean born

•  0sphyia 0sphyia

• Maternal diabetesMaternal diabetes

RDS - Protective factorsRDS - Protective factors

• ,R9M,R9M

• I(RI(R

• /teroids/teroids

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 RD- RD-Teaching Aids: NNF  ####

 0ntenatal corticosteroid 0ntenatal corticosteroid

  -- Simple therapy that saves neonatal livesSimple therapy that saves neonatal lives

• ,reterm labor #4-+4 !ee<s of gestation,reterm labor #4-+4 !ee<s of gestation

irrespective of ,R9M hypertension andirrespective of ,R9M hypertension and

diabetesdiabetes• oseDoseD

InF etamethasone 1#mg IM every #4 hrs BInF etamethasone 1#mg IM every #4 hrs B

# dosesG or InF eamethasone 6 mg IM# dosesG or InF eamethasone 6 mg IMevery 1# hrs B 4 dosesevery 1# hrs B 4 doses

• Multiple doses not beneficialMultiple doses not beneficial

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 RD- RD-Teaching Aids: NNF  #+#+

/urfactant therapy - Issues/urfactant therapy - Issues

• /hould be used only if facilities for/hould be used only if facilities for

ventilation availableventilation available

• CostCost

• ,rophylactic ?s rescue,rophylactic ?s rescue

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 RD- RD-Teaching Aids: NNF  #4#4

 

,rophylactic therapy,rophylactic therapy

  Etremely preterm >#= !<sEtremely preterm >#= !<s

>1 gm>1 gm

.ot routine in India.ot routine in India

  Rescue therapyRescue therapy

  0ny neonate diagnosed to have R/ 0ny neonate diagnosed to have R/

/urfactant therapy - Issues/urfactant therapy - Issues

Dose 100mg/kg phospholipid Intra trachealDose 100mg/kg phospholipid Intra tracheal

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 RD- RD-Teaching Aids: NNF  #7#7

  Meconium aspiration syndrome 3M0/5Meconium aspiration syndrome 3M0/5

• Meconium stainingMeconium staining

  - 0ntepartum intrapartum- 0ntepartum intrapartum

• *hin*hin

  - Chemical pneumonitis- Chemical pneumonitis

• *hic<*hic<

  - 0telectasis air!ay bloc<age air- 0telectasis air!ay bloc<age air

lea< syndromelea< syndrome

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 RD- RD-Teaching Aids: NNF  #6#6

Meconium aspiration syndromeMeconium aspiration syndrome

• ,ost term&/;,ost term&/;

• Meconium staining A cord nails s<inMeconium staining A cord nails s<in

• 9nset !ithin 4 to 6 hours9nset !ithin 4 to 6 hours

• 2yperinflated chest2yperinflated chest

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 RD- RD-Teaching Aids: NNF  #:#:

B-ray - M0/B-ray - M0/

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 RD- RD-Teaching Aids: NNF  #=#=

 M0/ - ,reventionM0/ - ,revention

• 9ropharyngeal suction before delivery of9ropharyngeal suction before delivery of

shoulder forshoulder for allall neonates born throughneonates born throughM/0;M/0;

• Endotracheal suction forEndotracheal suction for non vigorous'non vigorous'

neonates born through M/0;neonates born through M/0;  '' Avoid bag & mask ventilation till trachea is Avoid bag & mask ventilation till trachea is

cleared cleared 

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 RD- RD-Teaching Aids: NNF  #@#@

*ransient tachypnoea of ne!born*ransient tachypnoea of ne!born

3**.53**.5• Cesarean born term babyCesarean born term baby

• elayed clearance of lung fluidelayed clearance of lung fluid

• iagnosis by eclusioniagnosis by eclusion

• ManagementD supportiveManagementD supportive

• ,rognosis - good,rognosis - good

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 RD- RD-Teaching Aids: NNF  ++

X-ray- TTNBX-ray- TTNB

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 RD- RD-Teaching Aids: NNF  +1+1

Congenital pneumoniaCongenital pneumonia

Preis!osin" factorsPreis!osin" factors

  ,R9M $#4 hours foul smelling liuor,R9M $#4 hours foul smelling liuor

,eripartal fever unclean or multiple per,eripartal fever unclean or multiple pervaginalvaginal

TreatmentTreatment

  *hermoneutral environment .,9 I?*hermoneutral environment .,9 I?

fluids 9ygen antibiotics-fluids 9ygen antibiotics-

30mp)(entamicin530mp)(entamicin5

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 RD- RD-Teaching Aids: NNF  +#+#

B-ray A Congenital pneumoniaB-ray A Congenital pneumonia

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 RD- RD-Teaching Aids: NNF  ++++

 .osocomial pneumonia.osocomial pneumonia

  Ris< ;actorRis< ;actor D ?entilated neonatesD ?entilated neonates

  D ,reterm neonatesD ,reterm neonates

  ,revention,revention D 2and!ashD 2and!ash

D se of disposablesD se of disposables

  D Infection controlD Infection control

measures measures

  0ntibiotics 0ntibiotics D sually reuire higherD sually reuire higherantibiotics antibiotics 

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 RD- RD-Teaching Aids: NNF  +4+4

 Respiratory distress in a neonate !ithRespiratory distress in a neonate !ith

asphyiaasphyia

• Myocardial dysfunctionMyocardial dysfunction

• Cerebral edemaCerebral edema

•  0sphyial lung inFury 0sphyial lung inFury

• Metabolic acidosisMetabolic acidosis• ,ersistent pulmonary hypertension,ersistent pulmonary hypertension

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 RD- RD-Teaching Aids: NNF  +7+7

,neumothora,neumothora

Etio#o"yEtio#o"y

/pontaneous M0/ ,ositive pressure/pontaneous M0/ ,ositive pressureventilation 3,,?5ventilation 3,,?5

C#inica# feat$resC#inica# feat$res

/udden distress indistinct heart sounds/udden distress indistinct heart sounds

 

%ana"ement%ana"ement

  .eedle aspiration chest tube.eedle aspiration chest tube

 

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 RD- RD-Teaching Aids: NNF  +6+6

B-ray - ,neumothoraB-ray - ,neumothora

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 RD- RD-Teaching Aids: NNF  +:+:

,ersistent pulmonary,ersistent pulmonary

hypertension 3,,2.5hypertension 3,,2.5

Ca$sesCa$ses

• ,rimary,rimary

/econdaryD M0/ asphyia sepsis/econdaryD M0/ asphyia sepsis

%ana"ement%ana"ement

• /evere respiratory distress needing/evere respiratory distress needing

ventilatory support pulmonaryventilatory support pulmonaryvasodilatorsvasodilators

• ,oor prognosis,oor prognosis

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RDRDT hi Aid NNF +=+=

Respiratory distressRespiratory distress

 3needing referral53needing referral5

• R/ 32M5R/ 32M5

• M0/M0/• /urgical or cardiac cause/urgical or cardiac cause

• ,,2.,,2.

• /evere or !orsening distress/evere or !orsening distress