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STM JOURNALS Scientific Technical Medical www.stmjournals.com May-August 2014

Research & reviews a journal of pharmacognosy (vol1, issue2)

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Page 1: Research & reviews a journal of pharmacognosy (vol1, issue2)

STM JOURNALSScientific Technical Medical

www.stmjournals.com

May-August 2014

Page 2: Research & reviews a journal of pharmacognosy (vol1, issue2)

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Chairman

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Managing Director STM Journals, Consortium eLearning Network Pvt. Ltd.(CELNET)

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Industrial Tribology Machine Dynamics & Maintenance

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Alternative Energy Technology Laboratory,

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Page 5: Research & reviews a journal of pharmacognosy (vol1, issue2)

STM Journal (s) Advisory Board

Dr. Ashish RunthalaLecturer, Biological Sciences Group,

Birla Institute of Technology & Science, Pilani Rajasthan, India.

Dr. Baldev Raj

Former Director, Indira Gandhi Centre for Atomic Research, India.

Chairman, National Institute of Technology Puducherry, India.

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of Civil Engineering National Institute of Technology Trichy, India.

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Metallurgical and Materials Engineering National Institute of Technology,

Rourkela, India.

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AIIMS, New Delhi, India.

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Medicine, Maulana Azad Medical College, New Delhi, India.

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University, Baru Sahib, India.

Dr. Nandini Chatterjee SinghAssociate Professor,

National Brain Research Centre, Manesar, India.

Page 6: Research & reviews a journal of pharmacognosy (vol1, issue2)

Dr. Shankargouda PatilAsst. Prof., Department of Oral

Pathology, KLE Society's Institute of Dental Sciences, Bangalore, India.

Prof. Subash Chandra MishraProfessor, Metallurgical & Materials

Engineering Department, NIT, Rourkela, India.

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Osmanpura, Aurangabad, India.

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Indian Institute of Technology Madras, India.

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Nurture Earth R&D Pvt LtdMIT Campus, Beed bypass road,

Aurangabad, India.

Dr. Rakesh KumarAssistant Professor,

Department of Applied Chemistry, BIT Mesra, Patna, India.

Dr. Priyavrat TharejaHead, Materials and Metallurgical

Engineering department, PEC University of Technology,

Chandigarh, India.

STM Journal (s) Advisory Board

Page 7: Research & reviews a journal of pharmacognosy (vol1, issue2)

Editorial Board

Dr. Amita VermaHead, Department of Pharmaceutical

Sciences, SHIATS-Deemed University, Allahabad, India.

Dr. Bharat Bhusan SubudhiAssociate Professor,

School of Pharmaceutical Sciences,Siksha o Anusandhan University,

Bhubaneswar, India.

Dr. K.R. AryaPrincipal Scientist, Botany Division

CDRI, Lucknow,India.

Dr. K.L KrishnaAssistant Professor,Department Of

Pharmacology, JSS College Of Pharmacy, Mysore,India.

Dr. George D GeromichalosHead, Dept. Cell Culture, Molecular

Modeling & Drug Design Symeonidion Research Center Theagenion Cancer

Hospital. Symeonidi , Thessaloniki, Greece..

Dr. Anita MahapatraAssistant Professor Dept. of Natural

Products National Institute of Pharmaceutical Education and Research

(NIPER)Ahmedabad-Gujarat, India.

Dr. Laxmidhar MaharanaAssistant. ProfessorDepartment. of

Pharmacology School of Pharmaceutical

SciencesSiksha 'o' Anusandhan University

Kalinga Nagar, Ghatikia, Bhubaneswar,India.

Miss. Maushmi Shailesh KumarAssistant Professor,

Department of Pharmaceutical Biotechnology, SPPSPTM, NMIMS University,Vile Parle

West, Mumbai, India.

Dr. Muthyala Murali Krishna KumarAssistant Professor,College Of

Pharmaceutical Sciences,Andhra, India.

Dr. N. A. RautAssistantt. Professor (Sr. Gr.),Rashtrasant

Tukadoji Maharaj Nagpur University, Nagpur, India.

Dr. Parasuraman SubramaniSenior Lecturer, Faculty of Pharmacy,

AIMST University, Bedong 08100, Malaysia.

Dr. Prakash Rambhauji ItankarAssistant Professor (Sr.gr.), Department of Pharmaceutical Sciences, Rashtrasant

tukadoji Maharaj Nagpur University, India.

Page 8: Research & reviews a journal of pharmacognosy (vol1, issue2)

Editorial Board

Dr. Pratap SahuAssociate Professor Cum Deputy Dean ,School of Pharmaceutical Sciences,SOA University, India.

Dr. Snigdha PattnaikAssociate Professor,

School of Pharmaceutical Sciences, Siksha 'o' Anusandhan University

Ghatikia, Bhubaneswar, India.

Dr. Subhash MandalDivision of Pharmacognosy, Department of Pharmaceutical Technology Jadavpur

University Kolkata, India.

Dr. Sapna ShrikumarPrincipal, Moulana College of Pharmacy,

Angadtppuram, Malappuram, Kerala, India.

Dr. Surash RamanathanAssociate Professor,Centre for

Drug Research, Universiti Sains Malaysia, Penang.

Dr. SugatoAssistant Professor,Department of

Pharmaceutical Sciences,BIT, Mesra, India.

Dr. Arti GuptaAssistant Professor, Department of

Pharmacognosy ,UKA Tarsadia University, Maliba Pharmacy College, Surat, Gujarat ,

India

Mahesh RaoScientist, National Research Centre on Plant

Bitechnology, Pusa Campus, New Delhi

Dr. N. SilviaAssociate Professor, Shri Vishnu college of

Pharmacy, Panjagutta, Hyderabad, Andhra Pradesh , India.

Dr. Sridevi ChigurupatiSenior Lecturer, Faculty of Pharmacy,

AIMST University, Malaysia.

Dr. Rekha Raghuveer ShenoyAssociate Professor, Department of Pharmacology, Manipal College of

Pharmaceutical Sciences, Manipal ,India.

Page 9: Research & reviews a journal of pharmacognosy (vol1, issue2)

I take the privilege to present the print version for the [Volume 1 Issue (2)] of Journal of

Pharmacognosy. The intension of JoPC is to create an atmosphere that stimulates creativeness,

research and growth in the area of Pharmacognosy.

The development and growth of the mankind is the consequence of brilliant Research done by

eminent Scientists and Engineers in every field. JoPC provides an outlet for Research findings and

reviews in areas of Pharmacognosy found to be relevant for National and International recent

developments & research initiative.

The aim and scope of the Journal is to provide an academic medium and an important reference for

the advancement and dissemination of Research results that support high level learning, teaching and

research in the domain of Pharmacognosy.

Finally, I express my sincere gratitude and thanks to our Editorial/ Reviewer board and Authors for

their continued support and invaluable contributions and suggestions in the form of authoring write

ups/ reviewing and providing constructive comments for the advancement of the journals. With

regards to their due continuous support and co-operation, we have been able to publish quality

Research/Reviews findings for our customers base.

I hope you will enjoy reading this issue and we welcome your feedback on any aspect of the Journal.

Dr. Archana Mehrotra

Director

STM Journals

Director's Desk

STM JOURNALS

Page 10: Research & reviews a journal of pharmacognosy (vol1, issue2)

1. Indigenous Technical Knowledge Associated with Ethnomedicines in Banwar Village (Gwalior District), Madhya Pradesh, India

Mahesh Rao, Narendra S, Sangeeta M, Monika S, Karmakar P, Atmanand T, Sendhil R, Rajagopal V 1

2. Petroleum Ether, A Laboratory Solvent Induced Cannibalism, Piloerection and Straub Tail Reaction in Rodents Subramani Parasuraman, Gan Siaw Thing, Parayil Varghese Christapher, Sokkalingam Arumugam Dhanaraj 6

3. Unani Medicinal Plants with Anti-HIV PotentialQamar Uddin, Ahmad Sayeed, Khalid Mehmood Siddiqui 11

4. Pharmaco-Nutraceutical and Chromatographic Study of Wattakaka Volubilis (Linn. f.) Stapf. LeavesDevika Sharma, Sudipta Roy, Rabinarayan Acharya, Harisha C.R 23

ContentsJournal of Pharmacognosy

Page 11: Research & reviews a journal of pharmacognosy (vol1, issue2)

RRJoPC (2014)© STM Journals 2014. All Rights Reserved

Research & Reviews: A Journal of Pharmacognosy

Volume 1, Issue 2

www.stmjournals.com

Indigenous Technical Knowledge Associated with

Ethnomedicines in Banwar Village (Gwalior District),

Madhya Pradesh, India

Mahesh Rao1*, Narendra S

2, Sangeeta M

3, Monika S

4, Karmakar P

5,

Atmanand T6, Sendhil R

7, Rajagopal V

8

1Scientist, National Research Centre on Plant Biotechnology, New Delhi, India

2Scientist, Central Institute of Agricultural Engineering, Bhopal, India

3Scientist, National Bureau of Fish Genetic Resources, Lucknow, India

4Scientist, Central Arid Zone Research Institute, Jodhpur, India

5Scientist, Indian Institute of Vegetable Research, Varanasi, India

6Scientist, Central Research Institute for Jute & Allied Fibres, Barrackpore, India

7Scientist, Directorate of Wheat Research, Karnal, India

8Scientist, National Institute of Abiotic Stress Management, Baramati, India

Abstract Application of traditional knowledge is considered to be a simple and cost-effective way of immediate protection and well-being of living organisms in the society. However, the

technique and its application differ across regions. The main objective of the study was to

explore the indigenous techniques applied by the inhabitants of Banwar village, Madhya Pradesh, to protect the health of humans, crops and livestock through ethnomedicines.

The investigation has been carried out by a team of trainee scientists inducted for

National Agricultural Research System (NARS), India, during 2011-12. Snowball technique has been employed to select the respondents from Banwar. Observations

recorded by Participatory Rural Appraisal (PRA) in the village indicated different indigenous health practices employed by the villagers against various infections. Utilising

locally available materials by applying traditional knowledge immensely helped to get

immediate relief from the concerned problem. Further, the study revealed that the process

is cost-effective, time bound and eco-friendly.

Keywords: Traditional knowledge, Banwar, indigenous techniques, ethnomedicines

Page 12: Research & reviews a journal of pharmacognosy (vol1, issue2)

RRJoPC (2014)© STM Journals 2014. All Rights Reserved

Research & Reviews: A Journal of Pharmacognosy

Volume 1, Issue 2

www.stmjournals.com

Petroleum Ether, A Laboratory Solvent Induced

Cannibalism, Piloerection and Straub Tail

Reaction in Rodents

Subramani Parasuraman*, Gan Siaw Thing, Parayil Varghese Christapher,

Sokkalingam Arumugam Dhanaraj Unit of Pharmacology, Faculty of Pharmacy, Asian Institute of Medicine, Science and Technology

(AIMST) University, Bedong 08100, Kedah, Malaysia

Abstract Petroleum ether is one of the most commonly used solvent in extraction of

herbals/biological substances. In pharmacognostical studies, petroleum ether is used as a

solvent for extract of herbals which was used for further pharmacological investigation. In a few of their studies, the authors have observed petroleum ether-induced piloerection

which may be related to the herbal extract or trace solvent effect. Complete removal of

petroleum ether solvent in herbal extract is not possible because most of the time the final extract appears to be sticky-clay-like material. Hence the present study was carried out to

find the effect of petrolatum ether induced cannibalism, piloerection and straub tail reaction in rodents. Petrolatum ether was administered once daily at the dose levels of

50, 100, 250 and 500 mg/kg for 14 days. During the study dose dependent changes in

behaviour was observed with petroleum ether and cannibalism, piloerection and straub tail reactions.

Keywords: petroleum ether, piloerection, cannibalism, rodents

Page 13: Research & reviews a journal of pharmacognosy (vol1, issue2)

RRJoPC (2014)© STM Journals 2014. All Rights Reserved

Research & Reviews: A Journal of Pharmacognosy

Volume 1, Issue 2

www.stmjournals.com

Unani Medicinal Plants with Anti-HIV Potential

Qamar Uddin*, Ahmad Sayeed, Khalid Mehmood Siddiqui Central Council for Research in Unani Medicine (CCRUM), Janakpuri, New Delhi-110058, India

Abstract Acquired immune deficiency syndrome (AIDS) is a result of human immunodeficiency

virus (HIV) infection which subsequently leads to severe suppression of immune functions. AIDS is a significant threat to the health of mankind as there is no curative

treatment for HIV infection and AIDS. Current anti-retroviral therapies (ART) are quite

expensive or unaffordable by common man and are associated with adverse effects and rapid emergence of drug resistance. Therefore, the search for a new, safe, effective and

affordable anti-HIV/AIDS drug is a global concern. The aim of this review is to summarize research findings for Unani medicinal plants, which are endowed with the

ability to inhibit HIV. The present paper describes 22 Unani medicinal plants which have

been shown to inhibit infectivity and replication of HIV. Unani medicinal plants which are most effective and the most commonly studied in relation to AIDS are: Andrographis

paniculata, Croton tiglium, Curcuma longa, Hypericum perforatum, Momordica

charantia, Phyllanthus urinaria, Polyalthia suberosa and Terminalia chebula. However, clinical studies of these herbs need to be conducted for possible alternative medical

treatment of HIV infection and AIDS.

Keywords: Unani medicine, AIDS, HIV RNA, anti-HIV active compounds

Page 14: Research & reviews a journal of pharmacognosy (vol1, issue2)

RRJoPC (2014) © STM Journals 2014. All Rights Reserved

Research & Reviews: A Journal of Pharmacognosy

Volume 1, Issue 2

www.stmjournals.com

Pharmaco-Nutraceutical and Chromatographic Study of

Wattakaka Volubilis (Linn. f.) Stapf. Leaves

Devika Sharma1, Sudipta Roy

2, Rabinarayan Acharya

2, Harisha C.R

2

1Jamia Hamdard University, Department of Botany, New Delhi, India

2Institute for Post Graduate Teaching and Research in Ayurveda,

Gujarat Ayurved University, Jamnagar, India

Abstract Wattakaka volubilis (Linn.f.) stapf. (Asclepediaceae), twinning shrub, is used as a source plant of Jeevanti, an established drug of Ayurveda. Its leaves are used by the tribal

people as a source of vegetable. The present work has been undertaken, to establish the

necessary pharmacognostical, nutraceutical, physicochemical and HPTLC characters of leaves of Wattakaka volubilis following standard procedures. Results showed that the

leaves are simple, petiolated, opposite, cordate to ovate, hispidly hairy in younger parts.

In transverse section the leaf showed collenchyma with paracytic stomata, pericyclic fibers, rosette crystals etc. and stomata is 11–14 sq/mm in number. The preliminary

physio-chemical analysis showed the percentage of total ash (15.6%w/w), acid insoluble ash (2.512%w/w), loss on drying (8.73%w/w) etc. In HPTLC the leaf showed 7 spots in

254 nm and 8 spots at 366 nm. Nutraceuticall analysis showed the presence of nitrogen,

vitamin B1, vitamin B3, vitamin B6, vitamin C and folic acid.

Keywords: Dregea volubilis, Jeevanti, Nutraceutical, Pharmacognosy,

Wattakaka volubilis