Research & clinical assessment with the IBCMT Embedded Research Program

Research & clinical assessment with the IBCMT Embedded

Research Program

IBCMTThe Neuroscience Trust

Research & clinical assessment IBCMT’s Embedded Research Program

• Medical, Scientific, Education and Research Committee (MSERC)

• Partnership with Brain Resource Company

• IntegNeuro Cognitive assessment system– Clinical assessment of patients - chargeable– Collection of research data from patients– Continuing professional development

• The Neuroscience Trust


Embedded Research Program Aims and significance

• Creating an IBCMT clinical database

• Metal toxicity and neurocognitive function

• Data collected by international college membership using IntegNeuro

• Brain Resource normative database

• Development of an objective, evidence-based” “gold standard” for clinical use: toxicology profiles to inform the clinician


Embedded Research Program Affiliation with Brain Resource Company (BRC)

• IBMCT has entered partnership with BRC to develop the IBCMT clinical database

• IBCMT-BRC memorandum of understanding permits Colleges to enter the alliance with BRC [email protected]

• Each College may enter memorandum of understanding with BRC

• Accrual of research funds to IBCMT and affiliated Colleges based on the data contributed by clinicians to database


Embedded Research ProgramThe Database

• Toxicology groupings– Collection of data of over 5000 patients from

participating IBCMT clinics– Cognitive, clinical, toxicological and diagnostic

information– Collated with Brain Resource Database

• Normal reference group– 1500 normal cases to date using IntegNeuro

assessment– Aged 6– 85; males and females


• Phase 1• Data collection phase from up to 100 clinics worldwide• Clinic: assessment of cognitive function & treatment efficacy

• Phase 2• IBCMT and College sponsored research investigations into data to

determine toxicity profiles• Publication of discriminant analyses on metal toxins• Scientific enhancement of clinician’s diagnostic armory• Clinic: cognitive assessment and neurotoxicological profiling

Embedded Research ProgramTimeline


Neurocognitive assessment of patients in the clinic using

IntegNeuro


• Portable, computerized, automated assessment tool

• Easily locatable in IBCMT clinics • Hardware components:

• IBM Kiosk •Head phones and microphone•Web ready status

• IntegNeuro software

Neurocognitive assessment using IntegNeuro


Embedded Research ProgramData, tests and measurements

• Web questionnaire– Medical and other history

• IntegNeuro assessment– Neurocognitive function

• Clinical information– Hair analysis - toxic and nutrient elements,

blood and urine levels– Toxicological diagnosis– Clinical diagnosis


Neurocognitive assessment - staff training

• No psychological training required• Staff involvement with patient is

minimal• Patient orientation • Periodic patient monitoring

• Other staff activities• Entering clinical, toxicological and

diagnostic data• Data uploading and printing

Report• Billing patient • Paying the Neuroscience Trust

• Instructions on CD; internet and email support


• Patient allocated a unique code• Patient completes web

questionnaire at home or in clinic• Patient completes IntegNeuro

neurocognitive assessment in the clinic using the IntegNeuro Kiosk

• Clinical, toxicological and diagnostic data entered into Kiosk

• The data file is uploaded where it is automatically scored

• Report prepared and emailed for printing

Neurocognitive assessment – patient testing procedure


• The data uploading procedure is handled by internet connection

• Upload procedure secure and encrypted – no patient name; only ID code used

• Each upload takes a few minutes• Report returned by email from BRC

within 72 hours• Invoice emailed for payment • Payment for report made via

secure website at www.NeuroscienceTrust.com

• Clinic charged 85% of recommended List Price

Neurocognitive assessmentData upload


When to test and what to do if patient abnormal on IntegNeuro

• Initial testing provides an objective and inexpensive baseline of cognitive function

• If abnormal, then reassess patient after suitable interval to assess efficacy of treatment on these baseline measures as well as on toxicological measures

• If deemed necessary, refer for full neuropsychological assessment


IntegNeuroSummary of procedures

IntegNeuro test using allocated patient code

Patient auto tested using Kiosk (50min)

Report delivery by email

72 hour turnaround

Web Upload to BRC

Encrypted, de-linked data scored and

matched to database

Internet

Report payment

Https (secure) website

www.NeuroscienceTrust.com

IBCMTClinic

Report request uniquely linked to

patient code

Start


Installing IntegNeuro in the clinic


Steps to install IntegNeuro in clinic

• Clinic applies to The Neuroscience Trust• Application forms available from

[email protected]• IBM Kiosk and installed software delivered within 4-6

weeks of receipt of order• Installation and operation instructions provided with

equipment and software; telephone and web help as required

• IntegNeuro assessments can commence once equipment installed and connected to internet


Breakeven financial model for IntegNeuro installations

Current Recommended List Price for IntegNeuro reports 142$ Breakeven number of patients tested per week 1.036

Annual income from patient billing for reports 7,650less

Annual expenditure on assessments…Payment to Neuroscience Trust at 85% report retail price 6,502…Staff costs @ 20mins per patient @ $25 per hour 458

...Kiosk leasing (5y, 6%, 30%Res) 571

…Amortised establishment cost ($500, 5y, 6%) 119 7,649

Surplus (loss) 0

Kiosk sharing recommended if less than 2 tests per week

Amounts have been converted to US dollars


The Neuroscience Trust

• Established to manage the IBCMT-BRC strategic alliance involving– Embedded research program– Clinical report ordering and payments– Distribution of research funds to IBCMT and

participating National Colleges

• Web presence:– Support facility for clinics (e.g. FAQ, test information,

general procedures– Repository for research outputs– http://www.neurosciencetrust.com

Documents

Research & clinical assessment with the IBCMT Embedded Research Program