Reliability and Validity of the Toronto Structured Interview for Alexithymia in A

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    Reliability and validity of the Toronto Structured Interview for Alexithymia in a

    mixed clinical and nonclinical sample from Italy

    Vincenzo Caretti a,, Piero Porcelli b, Luigi Solano c, Adriano Schimmenti d,R. Michael Bagby e, Graeme J. Taylor f

    a Department of Psychology, University of Palermo, Palermo, Italyb Psychosomatic Unit, IRCCS De Bellis Hospital, Castellana Grotte, Italyc Department of Dynamic and Clinical Psychology, Sapienza University of Rome, Rome, Italyd Kore Department, Kore University of Enna, Enna, Italye University of Toronto and Centre for Addiction and Mental Health, Toronto, Canadaf University of Toronto and Mount Sinai Hospital, Toronto, Canada

    a b s t r a c ta r t i c l e i n f o

    Article history:

    Received 5 October 2010

    Received in revised form 12 December 2010

    Accepted 22 February 2011

    Keywords:

    Alexithymia

    Concurrent validity

    Confirmatory factor analysis

    Multimethod measurement

    Toronto Alexithymia Scale

    The reliability and validity of the Toronto Structured Interview for Alexithymia (TSIA) have been

    demonstrated in previous studies with English-speaking community and psychiatric samples and a

    German-speaking psychiatric sample. The aim of this study was to evaluate the psychometric properties of

    the TSIA in a mixed clinical and nonclinical sample from Italy. The original English version of the TSIA was

    translated into Italian and administered, along with the 20-item Toronto Alexithymia Scale (TAS-20), to 80

    healthy subjects, 69 medical outpatients, and 62 psychiatric outpatients. Eighty-one videotaped interviews

    were used for assessing the interrater reliability. Confirmatory factor analysis supported the hierarchical,

    four-factor structure of the TSIA obtained in previous studies, with four lower-order factors nested within two

    higher-order latent factors. The TSIA also demonstrated internal and interrater reliability, and concurrent

    validity with the TAS-20. The results support the use of the TSIA to assess alexithymia especially when a

    multimethod approach to measurement is possible.

    2011 Elsevier Ireland Ltd. All rights reserved.

    1. Introduction

    Over the past two decades several instruments have been

    developed to assess alexithymia, a construct characterized by

    difficulties in identifying and describing feelings, an impoverished

    fantasy life, and an externally oriented cognitive style (Nemiah et al.,

    1976). The currently available instruments include self-report scales,

    observer-rated questionnaires, structured interviews, and a projective

    test (Lumley et al., 2007; Porcelli and Mihura, 2010; Taylor et al.,

    2000). The most widely and frequently used instrument to assess

    alexithymia is the self-report 20-item Toronto Alexithymia Scale

    (TAS-20) (Bagby et al., 1994a), which has been translated into many

    different languages and validated in diverse cultural groups (Taylor

    et al., 2003; Zhu et al., 2007). As several researchers have noted,

    however, a potential limitation of the TAS-20 is whether respondents

    with high alexithymia are able to accurately appraise their capacity to

    identify and describe their feelings (Lane et al., 1998; Lumley et al.,

    2007). Other limitations include an overlap with self-report measures

    of negative affect, and an absence of items for assessing fantasy

    activity (these self-report items were found to be associated with a

    socially desirable response bias) (Bagby et al., 1994a; Leising et al.,

    2009; Lumley, 2000).

    Recognizing that all methods of assessing psychological constructs

    have some shortcomings, personality psychologists recommend the

    useof a multimethod approachto measurementas a wayof controlling

    for potentialmeasurementartifacts and thereby increasing the validity

    of research findings; although the correlations between different

    measures are often modest, an examination of both the convergences

    and divergences between measures can increase understanding of the

    underlying construct (Eid and Diener, 2006). In this same vein, Taylor

    andBagby(2004),Taylor et al.(2000) havelong recommended using a

    multimethod approach to assess alexithymia. Given that the construct

    was formulated originally on the basis of observations made during

    clinicalinterviews (Nemiah et al., 1976), Bagbyet al.(2006) developed

    the Toronto Structured Interview for Alexithymia (TSIA) as an

    interview-based method for measuring this construct.

    TheTSIA is composed of 24 interviewitems (i.e., questions), six for

    each of the four salient facets of the alexithymia construct: difficulty

    identifying feelings (DIF); difficulty describing feelings to others

    (DDF); an externally oriented style of thinking (EOT); and imaginal

    processes (IMP). Some example questions are: Are you sometimes

    Psychiatry Research 187 (2011) 432436

    Corresponding author at: Department of Psychology, University of Palermo, Viale

    delle Scienze, Edificio 15, 90128 Palermo, Italy. Tel.: +39 06 3219337, +39 333

    6315195 (mobile); fax: +39 06 3242336.

    E-mail address: [email protected] (V. Caretti).

    0165-1781/$ see front matter 2011 Elsevier Ireland Ltd. All rights reserved.

    doi:10.1016/j.psychres.2011.02.015

    Contents lists available at ScienceDirect

    Psychiatry Research

    j o u r n a l h o m e p a g e : w w w. e l s ev i e r. c o m / l o c a t e / p s yc h r e s

    http://dx.doi.org/10.1016/j.psychres.2011.02.015http://dx.doi.org/10.1016/j.psychres.2011.02.015http://dx.doi.org/10.1016/j.psychres.2011.02.015mailto:[email protected]://dx.doi.org/10.1016/j.psychres.2011.02.015http://www.sciencedirect.com/science/journal/01651781http://www.sciencedirect.com/science/journal/01651781http://dx.doi.org/10.1016/j.psychres.2011.02.015mailto:[email protected]://dx.doi.org/10.1016/j.psychres.2011.02.015
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    puzzled or confused by what emotion you are feeling?; Is it usually

    easy for you to find words to describe your feelings to others?; Do

    you tend to talk to others more about daily activities rather than

    feelings?; and When you think about some past eventsdo you relive

    and imagine them in your mind? For each interview question there

    are standardized prompts and/or probes designed to elicit responses

    that are scored according to guidelines outlined in a manual (Bagby

    et al., 2005).

    Factor analysis of the original English-language version of the TSIAwith community and psychiatric outpatient samples identified a

    hierarchical model with four lower-order factors nested within two

    higher-order factors consistent with the theoretical underpinnings of

    theconstruct (Bagby et al., 2006). TheDIF and DDFfacetscales formed

    a single higher-order domainscale labeled AffectAwareness (AA) and

    the EOT and IMP facet scales formed a single higher-order domain

    scale labeled Operative Thinking (OT). The TSIA also demonstrated

    acceptable levels of interrater, internal,and retest reliability, as well as

    concurrent validity with the TAS-20.

    Given the international interest in alexithymia research, it is

    important to develop different translations of the TSIA and evaluate

    the reliability and validity of these translations, as was done for the

    TAS-20. A German-language translation of the TSIA was developed

    and its psychometric properties evaluated with a mixed sample of

    psychiatric inpatients and outpatients (Grabe et al., 2009). Confirma-

    tory factor analysis supported the hierarchical, four-factor structure

    obtained with the original English version, and acceptable levels of

    internal and inter-rater reliability were also demonstrated. Support

    for the concurrent validity of the German translation of the TSIA was

    provided by significant correlations with the German translation of

    the TAS-20.

    The aim of the current study was to evaluate whether an Italian

    translation of the TSIA would demonstrate similar psychometric

    properties as the original TSIA and the German version of this

    instrument. We chose a mixed clinical and nonclinical sample to

    increase thevariabilityof TSIAscores acrossthe various analyses. Forthe

    clinical subsample, we chose diagnostic groups known to score higher

    on alexithymia measures than healthy individuals (Taylor, 2004),

    thereby increasing the distribution of scores in our combined sample.

    2. Methods

    2.1. Translation procedures

    As previously noted, the original English-language TSIA is composed of 24

    interview items, six items for each of the four facets of the alexithymia construct

    DIF, DDF, EOT, and IMP. Each interview question includes a set of prompts and/or

    probes, keyed to the thematic content of the item, to elicit information assisting in the

    accuracy of the scoring. All items are scored on a three-point scale ranging from 0 to 2

    with some scores based on the frequency of the presence of a characteristic, and others

    on the degree of the presence of the characteristic.

    Using the same format as the original English language version, the TSIA was

    translated into Italian by one of the investigators and then slightly revised after

    consultation with two of the other Italian-speaking investigators. This Italian

    translation was subsequently translated back into English by a bilingual teaching

    assistant whose mother-tongue was English and who had previous experiencetranslating psychology texts. The back-translation was reviewed by the primary

    developers of the English version of the TSIA who flagged any potential linguistic

    problems, which were then discussed with the Italian translators until there was

    consensus that cross-language equivalence was achieved.

    2.2. Participants

    Thestudysamplewascomposed ofa totalof 211(73men,and138women)subjects

    whowere either healthyindividuals, psychiatric outpatients,or medical outpatients;all

    wererecruitedbetweenNovember, 2007and July,2008 andall hadagreedto participate

    inthestudy. Themean ageofthetotalsamplewas 36.2 years(S.D.=12.3) andthemean

    years of education was 14.2 (S.D.=3.7). The healthy sample consisted of 80 (24 men,

    and 56 women) individuals with a meanage of35.8 years(S.D.= 11.3);the mean years

    of education was 15.8 (S.D.= 2.6). The psychiatric sample consisted of 62 (21 men, and

    41 women) outpatients with a mean age of 31.8 years (S.D.=11.8); mean years of

    education was 13.3 (S.D.=3.7). The medical sample consisted of 69 (28 men, and 41

    women) outpatients with a mean age of 40.5 years (S.D.= 12.5); mean years of

    education was 13.1 (S.D. =4.2). Gender was not distributed significantly differently

    across the groups, [2(2)=1.85; P=0.40]. The healthy individuals (i.e., nonclinical

    sample) had a higher level of education than both the psychiatric and medical patient

    samples, [F(2, 208)=13.72, Pb0.01]; there was no difference in years of education

    between the psychiatric and medical patient samples, [t (129)=0.30, P=0.76]. The

    psychiatric patients were younger than the medical patients, [t(129)=4.10, P=0.01]

    and healthy subjects, [t (140)=2.08, P=0.04]; and the medical patients were older

    than the healthy subjects, [t(147)=2.40, P=0.02].

    The psychiatric sample was composed of outpatients with generalized anxiety

    disorders (n =24) and dysthymic disorders (n =14) recruited from the Department of

    Developmental Psychiatry, Sapienza University of Rome and the Center for MentalHealth, ASL RomeE, and outpatients withanorexia nervosa (n =14) or bulimia nervosa

    (n =10) recruited from the Center for Eating Disorders, Sant'Orsola Malpighi Hospital,

    Bologna. The medical sample was composed of 69 outpatients with both essential

    hypertension and circulatory problems recruited from the Hypertension Clinic,

    Fatebenefratelli Hospital, Rome, and the UOC Cardiology Ward, San Filippo Neri

    Hospital in Rome, who had no self-reported psychiatric diagnoses in the past 5 years.

    The psychiatric and medical patients were recruited from among consecutive referrals

    to these psychiatric and medical outpatient clinics.

    The healthy (i.e., nonclinical) sample was composed of 80 individuals recruited

    from the student body and administrative staff employees at the Sapienza University

    of Rome and the University of Palermo, and from the administrative staff employees at

    the IRCCS hospital of Castellana Grotte. All were recruited via advertising or

    announcements at staff meetings. None of these subjects reported any current or

    chronic medical and psychiatric illnesses in the past 5 years.

    All subjects provided written informed consent prior to their participation. The

    studywas approvedby theEthics Committees at thevarious centers where participants

    were recruited. Subjects were excluded if aged b18 or N64 years, or if they were

    affectedby an organic brainsyndrome or other neurologic disorder,mental retardation,

    psychotic disorder, substance use disorder, chronic disease, or cancer.

    2.3. Interviewers and procedures

    Teninterviewers were initially givena trainingworkshopto become familiarwiththe

    alexithymia construct; they were also required to read and be familiar with the TSIA

    Manual (Bagby etal., 2005). Theseinterviewerswere further trained in the administration

    and scoring of the interviews by two of the investigators through discussion of guidelines

    forthescoring of theitems andthe correct useof thepromptsand probes. Allinterviewers

    transcribed verbatim the responses to the questions and the probes and scored the 24

    questions of the TSIA during the course of their interview. Each interviewer also

    videotaped 6 to 12 of their interviews to be used for assessment of interrater reliability.

    All participants were also administered the Italian translation of the TAS-20; the

    interviewers were masked to the scores of the participants. The TAS-20 is a reliable and

    valid self-report measure of alexithymia, and is comprised of three factor scales that

    assess three facets of the alexithymia construct DIF, DDF, and EOT (Bagby et al.,

    1994a, 1994b). The Italian translation of theTAS-20 has demonstratedfactorial validity,internal consistency in normal adult and clinical samples, and high testretest

    reliability over 2 weeks (Bressi et al., 1996).

    2.4. Confirmatory factor analysis (CFA)

    Confirmatory factoranalysisof theTSIAwas conductedfor thetotalsample (N=211)

    using LISREL8.80 with maximum likelihoodmethod of estimation(Jreskog and Srbom,

    2001). Following the validation procedure for the original English language TSIA ( Bagby

    et al., 2006), the factor solutions of the following models were evaluated:

    (a) Model 4a = a four-factor, nonhierarchical model with items from each of the

    item-facet sets serving as its own factor.

    (b) Model 4b = a four-factor, hierarchical model with each of the four item-facet

    sets nested under a single higher-order factor.

    (c) Model 4c = a four-factor, hierarchical model with the DIF and DDF item-facet

    sets nested under one higher-order factor labeled Affect Awareness (AA), and

    the EOT and IMP item-facet sets nested under a second higher-order factorlabeled Operatory Thinking (OT).

    (d) Model 3a = a three-factor, nonhierarchical model with items from the DIF and

    DDF item-facet sets forming a single factor and EOT and IMP item-facet sets

    forming separate single factors.

    (e) Model 3b = a three-factor, hierarchical model with each of the three factors

    identified in Model 3a nested under a single higher-order factor.

    (f) Model 2a = a two-factor model with the DIF and DDF item sets forming a

    single factor and the EOT and IMP item-facet sets forming a second, separate

    factor.

    (g) Model 2b = a two-factor, hierarchical model with the two factors identified in

    Model 2a nested under a single, higher-order factor.

    (h) Model 1a = a one-factor model with all of the items loading on a single factor.

    Goodness offit was assessed using both absolute and incremental fit indices. The

    absolute fit indices were the 2/d.f. ratio, with values between 4 and 2 indicating an

    adequate fit, and values 2 indicating a good fit; the standardized root mean square

    residual (SRMR), for which a cutoff valueof0.08 is recommended; and the root mean

    433V. Caretti et al. / Psychiatry Research 187 (2011) 432436

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    square error of approximation (RMSEA), for which values N0.10 indicate a poor fit,

    b0.08 an acceptable fit, and 0.05 a good fit (Brown, 2006; Hu and Bentler, 1999). The

    incremental fit indices were the comparative fit index (CFI), and the nonnormed fit

    index (NNFI); for both of these indices, values N0.90 indicate an acceptable fit and

    N0.95 a good fit (Hu and Bentler, 1999). The Chi square test of difference was used to

    determine which of the models provided the best relative fit. Based on a priori

    theoretical formulations and consistent with the empirical findings of Bagby et al.

    (2006) and Grabe et al. (2009), we predicted that Models 4a and 4c would provide the

    best fit to the data compared to the other models.

    2.5. Interrater and internal reliability

    Eighty-one of 90 videotaped interviews were of suitable audio quality for assessing

    interrater reliability. These videotaped interviews were randomly assigned to the four

    Italian investigators so thateach of themreceived between 15 and 25 interviews which

    they reviewed and rescored. These raters were blind to the scores made by the original

    interviewers as well as to the participants' TAS-20 scores.

    The interrater reliability was evaluated at both the individual item level for each of

    the 24 TSIA questions and at the total and subscale level. At each level of analysis, the

    agreement between the interviewers and the raters was estimated. At the item level,

    Cohen's kappa coefficient (Cohen, 1960) was used, and at the total TSIA and domain

    and facet scale level, the two-way mixed intraclass correlation coefficient (ICC) was

    used. For Cohen's kappa coefficient a probabilistic statistical significance can be

    generated; for the ICC, a value N0.60 represents adequate interrater reliability, and a

    value N0.80 represents good reliability (Landis and Koch, 1977).

    Internal reliability and item-to-scale homogeneity of the TSIA and its domain and

    facet scales were evaluated by calculating Cronbach's alpha coefficients and average

    inter-item correlations (AICs). The recommended standard for Cronbach's alpha is 0.70or higher; the optimal range for themean inter-item ris0.20to 0.40(Briggs and Cheek,

    1986; Nunnally and Bernstein, 1994).

    The concurrent validity was examined by correlating the TSIA total scale scores,

    and the domain and facet scales scores with the TAS-20 total and factor scale scores.

    3. Results

    3.1. Confirmatory factor analyses and model comparisons

    Prior to performing CFA and obtaining estimates of goodness-of-

    fit, we computed Mardia's coefficient of multivariate kurtosis to

    determine if the assumption of multivariate normality was met

    (Mardia, 1970). The sample was multivariate normally distributed at

    the 0.05 level of significance (Mardia's statistic=1.726, P=0.08).

    The goodness-of-fit indices for each of the models are shown inTable 1. The indices indicate that the four-factor models (4a, 4b, and

    4c) provided good fits to the data, the three-factor and two-factor

    models provided adequate fits, and the one-factor model provided a

    poor fit. As predicted, model comparison testing revealed that Model

    4b fit less well than Model 4a (2(2)=6.05, P=0.049) and Model 4c

    (2(1)=5.73, P= 0.017), while no difference was found between

    Models4a and 4c(2(1)=0.32, P=0.57). In Table 2 the item-to-facet

    scale parameter estimates for the hierarchical, four-factor structure of

    the TSIA are displayed for Model 4c. The mean scores and standard

    deviations for the TSIA and its domain and facet scales are shown in

    Table 3 for the total sample and also separately for the healthy

    subjects, and the psychiatric and medical patient samples.

    3.2. Intercorrelations of the TSIA and its scales

    Pearson correlations between the TSIA and its domain and facet

    scales for the total sample are shown in Table 4; all correlations are

    statistically significant (P0.01).

    Table 1

    Confirmatory factor analysis goodness-of-fit results for alternative TSIA factor structure

    models for the total sample (N=211).

    Model Goodness offit statistics

    2 (d.f.) 2/d.f. ratio SRMR CFI NNFI RMSEA (95% CI)

    Four-factor models4a 345.75 (246) 1.41 0.066 0.97 0.97 0.040 (0.0280.051)

    4b 351.80 (248) 1.42 0.069 0.96 0.96 0.045 (0.0330.055)

    4c 346.07 (247) 1.40 0.066 0.97 0.97 0.040 (0.0280.051)

    Three-factor models

    3a 440.94 (249) 1.77 0.077 0.92 0.91 0.065 (0.0560.074)

    3b 450.67 (250) 1.80 0.077 0.92 0.91 0.064 (0.0550.073)

    Two-factor models

    2a 497.74 (251) 1.98 0.078 0.91 0.90 0.068 (0.0600.077)

    2b 497.74 (250) 1.99 0.079 0.91 0.90 0.069 (0.0600.077)

    One-factor model

    1a 570.14 (252) 2.26 0.080 0.84 0.83 0.091 (0.0830.099)

    d.f. = degrees of freedom; SRMR = standardized root mean square residual; CFI =

    comparative fit index; NNFI = nonnormed fit index; RMSEA (95% CI) = root mean

    square error of approximation (95% confidence interval).

    Table 2

    Item factor loadings from the 4-factor, hierarchical model ( N=211).

    Item Affect awareness Operative thinking

    Factor 1 Factor 2 Factor 3 Factor 4

    Difficulty identifying feelings (DIF)

    Item 1 0.58

    Item 5 0.49

    Item 9 0.54

    Item 13 0.60

    Item 17 0.43

    Item 21 0.52

    Difficulty describing feelings (DDF)

    Item 2 0.74

    Item 6 0.65

    Item 10 0.50

    Item 14 0.75

    Item 18 0.49

    Item 22 0.35

    Externally oriented thinking (EOT)

    Item 3 0.48

    Item 7 0.42

    Item 11 0.62

    Item 15 0.68

    Item 19 0.47

    Item 23 0.50

    Imaginal processes (IMP)

    Item 4 0.59

    Item 8 0.62

    Item 12 0.42

    Item 16 0.62

    Item 20 0.46

    Item 24 0.72

    Table 3

    Mean scores and standard deviations for the TSIA and TAS-20 for the total sample and

    for the healthy, medical, and psychiatric subsamples.

    Total sample

    (N=211)

    Healthy subjects

    (N=80)

    Medical patients

    (N=69)

    Psychiatric patients

    (N=62)

    Mean (S.D.) Mean (S.D.) Mean (S.D.) Mean (S.D.)

    TSIA 22.96 (8.97) 18.40 (7.90) 25.28 (8.97) 25.26 (8.26)

    AA 11.05 (5.30) 8.93 (4.57) 11.43 (5.81) 13.37 (4.51)

    OT 11.61 (5.01) 9.50 (4.26) 13.80 (4.63) 11.90 (5.24)

    DIF 4.94 (2.84) 3.81 (2.58) 5.19 (2.95) 6.13 (2.49)

    DDF 6.11 (3.13) 5.11 (2.68) 6.25 (3.61) 7.24 (2.71)

    EOT 6.09 (2.99) 5.10 (2.70) 6.94 (2.97) 6.44 (3.04)

    IMP 5.52 (2.91) 4.40 (2.41) 6.86 (2.79) 5.47 (3.06)

    TAS-20 45.19 (12.84) 42.20 (11.10) 46.00 (14.36) 48.25 (12.52)

    F1 15.69 ( 6.53) 14.89 ( 5.28) 15.31 (7.25) 17.22 ( 7.02)

    F2 12.62 ( 4.89) 12.24 ( 4.65) 12.58 (5.46) 13.17 ( 4.53)

    F3 16.93 ( 5.14) 15.06 ( 4.55) 18.63 (5.69) 17.50 ( 4.43)

    AA = affect awareness; OT = operative thinking; DIF = difficulty identifying feelings;

    DDF = difficulty describing feelings; EOT = externally oriented thinking; IMP =

    imaginalprocesses; F1 = difficultyidentifying feelingsfactor;F2 = difficulty describing

    feelings factor; F3 = externally oriented thinking factor.

    434 V. Caretti et al. / Psychiatry Research 187 (2011) 432436

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    3.3. Interrater and internal reliability

    In the random subsample of 81 interviews, the ICC reliability

    estimates were 0.94 (Pb0.01) for the TSIA, 0.91 (Pb0.01) for the AA

    domain scale, 0.95 (Pb0.01) for the OT domain scale, 0.93 (Pb0.01)

    for the DIF facet scale, 0.89 (Pb0.01) for the DDF facet scale, 0.93

    (Pb0.01) for the EOT facet scale, and 0.95 (Pb0.01) for the IMP facet

    scale. All of these ICC values indicate good to excellent interrater

    reliability at the scale level. At the item level, the chance-corrected

    Cohen's kappa coefficient was significant (Pb0.01) for all items,

    ranging from 0.56 (item 5) to 0.96 (item 16), indicating moderate to

    almost perfect scoring agreement between the interviewers and the

    raters.

    The AICs and Cronbach for the TSIA and its domain and facetscales in thetotal sampleare displayedin Table 5. The AICs werein the

    recommended range of 0.20 to 0.40, indicating adequate item-to-scale

    homogeneity for the TSIA and its domain and facet scales. Cronbachcoefficients for the TSIA and its domain and facet scales ranged from

    0.70 to 0.86, thus showing adequate internal reliability.

    3.4. Concurrent validity

    The Pearson correlations between the TSIA and its domain and

    facet scales and the TAS-20 and its three factor scales for the total

    sample are displayed in Table 6. Almost all of the correlations are

    significant. It is interesting to notethatthe DIF factor ofthe TAS-20 did

    not correlate significantly with the OT domain scale of the TSIA and

    correlated weakly and negatively with the IMP scale, which, in turn,

    correlated positively and significantly only with theEOT factor scaleof

    the TAS-20.

    4. Discussion

    In this study, we were successful in replicating the hierarchical,

    four-factor model of the TSIA using an Italian translation of the

    instrument and a mixed sample comprised of medical and psychiatricoutpatients and healthy subjects from various parts of Italy. As in the

    development of the TSIA (Bagby et al., 2006), and in the study with

    German-speaking psychiatric patients (Grabe et al., 2009), we used

    confirmatory factor analysis to test several different structural

    models. Model comparison testing revealed the superiority of both

    the hierarchical, four-factor model (Model 4c) and the nonhierarchi-

    cal, four-factor model (Model 4a) over three-, two-, and one-factor

    models. These results, and similar findings from the study with

    German-speaking patients, strongly support the hierarchical, four-

    factor structure obtained by Bagby et al. (2006), who had considered

    the configuration of the domain and facet scales provisional until this

    structure could be replicated in other samples. Although statistically

    there was no significant difference in fit between the hierarchical and

    nonhierarchical four-factor models, as Bagby et al. (2006) indicated,

    the hierarchical model is preferred as it is consistent with Nemiah

    et al.'s (1976) theoretical conception that the alexithymia construct

    comprises a deficit in affect awareness characterized by difficulties in

    identifying and describing subjective emotional feelings, and an

    operative thinking style (pense opratoire), which is characterized by

    an absence or paucity of fantasies referable to drives and feelings

    and a preoccupation with the details of external events (p. 433). The

    lower-order facet scales of DIF and DDF comprise a single higher-

    order domain of affect awareness (AA); and the lower-order facet

    scales of EOT and IMP comprise a single higher-order domain ofoperative thinking (OT). But despite the theoretical rationale, further

    research is needed to determine whether the hierarchical model is

    more robust and clinically useful than the nonhierarchical model.

    The finding of significant correlations among the domain and facet

    scales and between these scales and the total TSIA is consistent with

    the view that alexithymia is a coherent, but multifaceted construct. As

    with other multifaceted constructs, however, one would expect to

    find that individual TSIA facet scales sometimes correlate more

    strongly than the total TSIA with measures of constructs that are

    closely related to the particular alexithymia facet (Carver, 1989).

    The TSIA and its domain and facet scales also demonstrated

    adequate internal reliability and item-to-scale homogeneity in the

    Italian sample. The Cronbach alpha coefficients and AICs all met the

    criterion standards and are comparable to those found in earlierstudies (Bagby et al., 2006; Grabe et al., 2009).

    A potential weakness of structured and semi-structured inter-

    views is in establishing interrater agreement. With our Italian-

    speaking sample we were able to achieve statistically significant

    estimates of interrater reliability for the TSIA and its domain and facet

    scales. Earlier studies with English-speaking community and psychi-

    atric samples, and German-speaking psychiatric samples, also

    demonstrated adequate to good interrater reliability for the TSIA

    (Bagby et al., 2006; Grabe et al., 2009).

    Concurrent validity of the Italian-language version of the TSIA was

    demonstrated by the significant correlations with the Italian transla-

    tion of the TAS-20. The magnitude of the correlations between the

    TSIA and its facet and domain scales and the TAS-20 and its factor

    scales was similar to those obtained with the English- and German-

    Table 4

    Pearson correlations among the TSIA and its domain and facets scales in the total

    sample (N=211).

    TSIA AA OT DIF DDF EOT IMP

    TSIA

    AA 0.88

    OT 0.87 0.53

    DIF 0.76 0.88 0.44

    DDF 0.80 0.90 0.50 0.58

    EOT 0.81 0.60 0.85 0.50 0.52 IMP 0.66 0.32 0.85 0.24 0.32 0.44

    All correlations are significant at P0.01.

    AA = affect awareness; OT = operative thinking; DIF = difficulty identifying feelings;

    DDF = difficulty describing feelings; EOT = externally oriented thinking; IMP =

    imaginal processes.

    Table 5

    Cronbach's alpha and mean inter-item correlations for the TSIA and its domain and

    facet scales in the total sample (N=211).

    Cronbach's AIC

    Total TSIA 0.86 0.21

    AA 0.82 0.27

    OT 0.79 0.24

    DIF 0.70 0.28

    DDF 0.75 0.32

    EOT 0.70 0.24

    IMP 0.74 0.27

    AIC = average inter-item correlation.

    Table 6

    Correlations between the TSIA and the TAS-20 in the total sample (N=211).

    TAS-20 F1-DIF F2-DDF F3-EOT

    TSIA 0.44 0.22 0.40 0.47

    AA 0.53 0.39 0.49 0.38

    OT 0.25 0.01 0.21 0.44

    DIF 0.50 0.45 0.42 0.30

    DDF 0.44 0.25 0.44 0.37

    EOT 0.36 0.15 0.28 0.47

    IMP 0.05 0 .16

    0.07 0.28

    AA = affect awareness; OT = operative thinking; DIF = difficulty identifying feelings;

    DDF = difficulty describing feelings; EOT = externally oriented thinking; IMP =

    imaginal processes. Pb0.01. Pb0.05.

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    language versions of the TSIA (Bagby et al., 2006; Grabe et al., 2009).

    The magnitude of the correlation between the TSIA and TAS-20 total

    scores is also similar in magnitude to correlations that have been

    reported between the TAS-20 and other non-self-report measures of

    alexithymia including the Observer Alexithymia Scale (Berthoz et al.,

    2007; Dorard et al., 2008) and the modified Beth Israel Hospital

    Psychosomatic Questionnaire (Arimura et al., 2002).

    As Bagby et al. (2006) reported with their combined community

    and psychiatric sample, in our mixed clinical and nonclinical sample,the TSIA DIF, DDF, and EOT facet scales correlated moderately with

    their corresponding TAS-20 factor scales. The nonsignificant or low

    magnitude correlations between the IMP facet scale and the TAS-20

    and its factors was not unexpected since the TAS-20 does not contain

    items for assessing fantasizing and other imaginal processes; the

    significant, albeit weak, correlation of IMP with the EOT factor of the

    TAS-20 is consistent with an earlier finding that this TAS-20 factor

    correlates significantly and negatively with a measure of fantasy

    (Bagby et al., 1994b).

    Overall, the results of this study provide further support for the

    reliability and validity of the TSIA most generally and for the Italian

    language version more specifically. Moreover, the good to excellent

    estimates of interrater reliability support Bagby et al.'s (2006) view

    that non-expert research assistants can be trained to administer and

    score theTSIA.Althoughfurther studies areneeded to assessthe retest

    reliability and the convergent and discriminant validity of the TSIA, it

    provides a comprehensive assessment of the alexithymia construct

    and can be recommended for clinical and research purposes. In

    general,a multimethod approachto assessing alexithymia is preferred,

    but this is not always feasible in clinical situations and in some

    research investigations due to the time involved in administering the

    TSIA. Whereas the standardized prompts and probes of the TSIA

    permit an assessment that avoids the potentiallimitation of self-report

    measures that assume that respondents are aware of any deficits in

    emotionalself-awareness,the TAS-20 has the advantageof being quick

    to administer, inexpensive, and simple to score. The use of both

    measures would be especially useful in investigations that need to

    maximizethe likelihood that subjects are correctlyclassifiedashighor

    low alexithymia individuals, such as brain imaging studies whichgenerally require small size samples (Moriguchi et al., 2006).

    Acknowledgments

    The authors are grateful to Alessandra Ciolfi, Arianna Franchi,

    Marta Lepore, Fabio Monticelli, Alessia Zangrilli, Francesca Amati,

    Maria Bonadies, Michela Di Trani, Silvia Ferrara, and Luisa Pepe for

    their valuable contribution in performing the interviews.

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