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Regenerative Medicine & Stem Cells-2013 Theme: A New Hope for Medical Science Preliminary Program Opening Ceremony & Keynote Forum of Global Health Conference-2013 Time: 09:00-12:05,Oct. 12, 2013 Place: Room No.303, 3rd Floor, Dalian International Conference Center Moderator Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the Genomics Research Center, Academia Sinica, Taiwan 09:30-09:35 Moderator's Introduction 09:35-10:05 Title: Gene and Stem Cell Therapy for Diabetes - Some Thoughts and Candid Questions Dr. Roy Yorke Calne, Emeritus Professor, Cambridge University, UK 10:05-10:35 Title: Dietary Supplements: What Consumers Should Know Dr. Sally Greenberg, Executive Director, National Consumers League, USA 10:35-11:05 Title: Micronutrient Intake and Economic impact of Malnutrition A Global Perspective Dr. Eggersdorfer Manfred, Senior Vice-President, DSM Nutritional Products, Switzerland 11:05-11:35 Title: Connected Innovation: The Power of Many Dr. Bernhard van Lengerich, Chief Science Officer & Vice President, General Mills Inc., USA 11:35-12:05 Title: Aging and Hearing Disorders Dr. Steven Juhn, Professor and Director, Auditory Biochemistry Laboratory, University of Minnesota, USA 12:10-13:10 Luncheon

Regenerative Medicine & Stem Cells-2013pic.biodiscover.com/files/3/h9/biodiscover1381490091... · 2013-10-11 · 11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

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Page 1: Regenerative Medicine & Stem Cells-2013pic.biodiscover.com/files/3/h9/biodiscover1381490091... · 2013-10-11 · 11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

Regenerative Medicine &

Stem Cells-2013

Theme: A New Hope for Medical Science

Preliminary Program

Opening Ceremony & Keynote Forum of Global Health Conference-2013

Time: 09:00-12:05,Oct. 12, 2013 Place: Room No.303, 3rd Floor, Dalian International Conference Center

Moderator Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the

Genomics Research Center, Academia Sinica, Taiwan

09:30-09:35 Moderator's Introduction

09:35-10:05

Title: Gene and Stem Cell Therapy for Diabetes - Some Thoughts and Candid Questions

Dr. Roy Yorke Calne, Emeritus Professor, Cambridge University, UK

10:05-10:35

Title: Dietary Supplements: What Consumers Should Know

Dr. Sally Greenberg, Executive Director, National Consumers League, USA

10:35-11:05

Title: Micronutrient Intake and Economic impact of Malnutrition – A Global Perspective

Dr. Eggersdorfer Manfred, Senior Vice-President, DSM Nutritional Products, Switzerland

11:05-11:35

Title: Connected Innovation: The Power of Many

Dr. Bernhard van Lengerich, Chief Science Officer & Vice President, General Mills Inc., USA

11:35-12:05

Title: Aging and Hearing Disorders

Dr. Steven Juhn, Professor and Director, Auditory Biochemistry Laboratory, University of

Minnesota, USA

12:10-13:10 Luncheon

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Plenary Lectures

Time: 13:30-16:40, October 14, 2013 (Monday); Place: Room No. 307A, 3rd Floor, DICC

Moderator Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the

Genomics Research Center, Academia Sinica, Taiwan

13:30-13:40 Moderator’s Introduction

13:40-14:10 Title: Mir-302 Contributes to Tumorigenicity through Promoting G1 to S Transition and

Maintaining OCT4 Overexpression by Inhibiting AKT1

Dr. Chunhua Zhao, Director, Center of Excellence in Tissue Engineering, Chinese Academy of

Medical Sciences; Professor, Peking Union Medical College, Chinese Academy of Medical

Sciences, China

14:10-14:40 Title: The Mechanism and Role of MMPs in Soft Tissue Injury and Regeneration

Dr. Kuo-Li Paul Sung, Director and Professor, University of California at San Diego, USA:

Distinguish Professor, Chongqing University, China

14:40-15:10 Title: Stem Cell Marker Lgr5 and its Relatedness with Other Putative Markers of Cancer Stem

Cells in Gastric Adenocarcinoma

Dr. Wufang Fan, Director and Professor, Hebei University, China

15:10-15:40 Title: Stem Cells and Transcription Factors in Oral and Craniofacial Tissue Regeneration

Dr. Jake (Jinkun) Chen, Professor and Director, Division of Oral Biology, Tufts University, USA

15:40-16:10 Title: Functionally Mature Innate-Immune-Ralated Cells Derived from Human Pluripotent Stem

Cells

Dr. Feng Ma, Professor, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical

College, (PUMC)

16:10-16:40 Title: Immune Modulation by Mesenchymal-like Stromal Cells–Lessons from Clinical Trials

Dr. Hans-Dieter Volk, Director, Berlin-Brandenburg Center for Regenerative Therapies (BCRT),

Charite-University Medicine Berlin, Germany

Track 1: Landscape and Outlook of Global Stem Cell

Session 1-1: Legal, Politics, Ethic, and Social Acceptance of Stem Cell Research

Time: 13:30-15:05, October 12, 2013 (Saturday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Oktay Kadayifci, Professor, Ob & Gyn and Perinatology, The University of Cukurova; Head,

The Onkim Stem Cell Technologies, Turkey

13:30-13:35 Chair’s Introduction

13:35-14:05 Title: What Can Be Done with the IVF Excess Embryos? Just to Destroy or Use Them for the

Sake of Humanity?

Dr. Oktay Kadayifci, Professor, Ob & Gyn and Perinatology, The University of Cukurova; Head,

The Onkim Stem Cell Technologies, Turkey

14:05-14:35 Title: Lessons from the Vogue for ―Stem Cell Therapy‖ in Inland China: Ethical and Policy Issues

Dr. Renzong Qiu, Emeritus Professor, Institute of Philosophy, Chinese Academy of Social

Sciences; Professor and Chair, Center for Bioethics, Chinese Academy of Medical

Page 3: Regenerative Medicine & Stem Cells-2013pic.biodiscover.com/files/3/h9/biodiscover1381490091... · 2013-10-11 · 11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

Sciences/Peking Medical College, China; Vice-President, National Ethics Committee, the Ministry

of Health, China

14:35-15:05 Title: Legal and Political Debate on Stem Cell Research and Therapy in South Korea

Dr. So Yoon Kim, Associate Professor, Yonsei University, South Korea

15:05-15:30 Coffee Break

Session 1-2: Global Stem Cell and Tissue Engineering Projects

Time: 13:30-15:35, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Stefanos Theoharis, Chief Business Officer, apceth GmbH & Co KG, Germany

13:30-13:35 Chair’s Introduction

13:35-13:55 Title: Development of Pharmaceutical Grade Advanced Therapeutics (ATMPs) for the European

& Global Market

Dr. Stefanos Theoharis, Chief Business Officer, apceth GmbH & Co KG, Germany

13:55-14:15 Title: In Vitro Vascularization of 3-D Functional Tissues

Dr. Tatsuya Shimizu, Professor, Institute of Advanced Biomedical Engineering and Science,

Tokyo Women’s Medical University, Japan

14:15-14:35 Title: Industrial Aspects of Allogeneic Mesenchymal Stromal Cell (MSC) Expansion and

Treatment

Dr. Chi-Meng Tzeng, Professor and Executive Director, Translational Medicine Center, Xiamen

University, China

14:35-14:55 Title: Engineering Cell Surfaces for Tissue Assembly

Dr. Muhammad N. Yousaf, Professor & Chair, Department of Chemistry, York University,

Canada

14:55-15:15 Title: Cell Blebbing in Cryopreservation: A Self-Protection Mechanism of Cells

Dr. Weiping Ding, Associate Professor, Centers for Biomedical Engineering, University of

Sciences and Technology of China, China

15:15-15:35 Title: Transvasal and Intrapulmonal Delivery of Autologous Mesenchymal Stem Cells in Patients

with Severe Pulmonary Arterial Hypertension

Dr. Aris Lacis, Head, Clinic of Pediatric Cardiology and Cardiac Surgery, University Hospital for

Children, Latvia

Track 2: Breaking Research Development in Stem Cell

Session 2-1: Stem Cell Genomics, Epigenetics & Systems Biology

Time: 15:30-17:40, October 12, 2013 (Saturday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Qiao Li, Assistant Professor/Principle Investigator, Faculty of Medicine, University of Ottawa,

Canada

15:30-15:35 Chair’s Introduction

15:35-16:00 Title: Transcriptional Regulation of Myogenic Differentiation

Dr. Qiao Li, Assistant Professor/Principle Investigator, Faculty of Medicine, University of Ottawa,

Canada

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16:00-16:25 Title: Reprogramming towards Pluripotency Requires SMC1-Dependent Intrachromosomal

Looping

Dr. Jifan Hu, Professor, First Hospital, Jilin University, China; Director, Stem Cell and Cancer

Epigenetics Program, VA Palo Alto Health Care System, Stanford University Medical School,

USA

16:25-16:50 Title: The Biological Characteristics of Human Umbilical Cord Mesenchymal Stem Cells

Dr. Ma Lian, Vice President, Department of Pediatrics, Second Affiliated Hospital of Shantou

University Medical College, China

16:50-17:15 Title: Epigenetic Regulator Promotes Differentiation from Bone Marrow Derived-Mesenchymal

Stem Cells

Dr. Hye Joung Kim, Research Fellow, The Catholic University of Korea Seoul ST. Mary's

Hospital, South Korea

17:15-17:40 Title: Expression of RBMX after Spinal Cord Injury in Rats

Dr. Zhi-ming Cui, Head, Department of Spine Surgery, The Second Affiliated Hospital of

Nantong University, China

Session 2-2: Stem Cell Lineage, Derivation and Differentiation

Time: 08:30-10:05, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Weidong Le, Professor of Neurology, Baylor College of Medicine, USA; Professor and

Principal Investigator, Institute of Health Sciences, SIBS, CAS, China

08:30-08:35 Chair’s Introduction

08:35-09:05 Title: Microrna Regulation of Stem Cells Differentiation into Dopamine Neurons

Dr. Weidong Le, Professor of Neurology, Baylor College of Medicine, USA; Professor and

Principal Investigator, Institute of Health Sciences, SIBS, CAS, China

09:05-09:35 Title: Enhanced Remyelinating and Immunomodulatory of Neural Stem Cells by Transduction of

Neurotrophin 3

Dr. Jingxian Yang, Director, Liaoning University of Traditional Chinese Medicine, China

09:35-10:05 Title: Characterization of Human Embryonic Stem Cells Differentiation to Bone Forming Cells

Dr. Amer Mahmood, Assistant Professor, King Khalid University Hospital King Saud University,

Saudi Arabia

10:05-10:30 Coffee Break

Session 2-3: Stem Cell Niches

Time: 10:30-12:15, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Karl Tryggvason, Professor, Karolinska Institute, Sweden; Tanoto Professor, Duke-NUS

Graduate Medical School, Singapore

Co-Chair Dr. Gigi Ngar Chee Chiu, Assistant Professor, University of Singapore, Singapore

10:30-10:35 Chair’s Introduction

10:35-11:00 Title: Laminins - Extracellular Signaling Molecules in Differentiation and Phenotype Stability

Dr. Karl Tryggvason, Professor, Karolinska Institute, Sweden; Tanoto Professor, Duke-NUS

Graduate Medical School, Singapore

Page 5: Regenerative Medicine & Stem Cells-2013pic.biodiscover.com/files/3/h9/biodiscover1381490091... · 2013-10-11 · 11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

Dr. Chunyi Li, Executive Director, State Key Laboratory for Molecular Biology of Special

Economic Animals, China

11:25-11:50 Title: Enhanced ex Vivo Expansion of Hematopoietic Stem/Progenitor Cells from Umbilical Cord

Blood by Functionalized Carbon Nanotubes

Dr. Gigi N. C. Chiu, Assistant Professor, National University of Singapore, Singapore

11:50-12:15 Title: Ubiquitination of Protease A20 Inhibited the Initiation of Caspase-8 in Brain Tumor Stem

Cells with TRAIL Resistance

Dr. Ling Qi, Director, Jilin Medical College, China

Session 2-4: Cancer Stem Cell (Part One)

Time: 08:30-12:10, October 13, 2013 (Sunday); Place: Room No. 621, 6th Floor, DICC

Chair Ms. Maria Cristina Tanzi, Director of Biomaterials Lab, Chemistry, Materials and Chemical

Engineering Department, Politecnico di Milano, Italy

Co-Chair Dr. Xiubao Chang, Associate Professor, Department of Biochemistry and Molecular Biology,

Mayo Clinic College of Medicine, USA

08:30-08:35 Chair’s Introduction

08:35-09:00 Title: PEG-Based Matrices for the in Vitro Study of Cancer Stem Cells under Non-Adhesive

Conditions

Ms. Maria Cristina Tanzi, Director of Biomaterials Lab, Chemistry, Materials and Chemical

Engineering Department, Politecnico di Milano, Italy

09:00-09:25 Title: Cancer Stemness in Mucinous Colon Cancer

Dr. Kiichiro Tsuchiya, Associate Professor, Department of Advanced Therapeutics for

Gastrointestinal Diseases, Tokyo Medical and Dental University, Japan

09:25-09:50 Title: Epigenetic and Genetic Involvements on CSCs (Cancer Stem Cells) Phenotype

Development: Possible Mechanism of Development and Potent Drugable Targets

Dr. Ioannis Papasotiriou, Director, Research Genetic Cancer Centre, Greece

09:50-10:15 Title: Immunotherapy Targeting Esophageal Cancer Stem Cells

Dr. Yi Zhang, Director and Professor, The Biotherapy Center and the Department of Oncology,

The First Affiliated Hospital, Zhengzhou University, China

10:15-10:30 Coffee Break

10:30-10:55 Title: Human Breast Cancer Stem Cells Have Significantly Higher Rate of Clathrin-Independent

and Caveolin-Independent Endocytosis than the Differentiated Breast Cancer Cells

Dr. Xiubao Chang, Associate Professor, Department of Biochemistry and Molecular Biology,

Mayo Clinic College of Medicine, USA

10:55-11:20 Title: Eradication of Gastrointestinal Cancer Stem Cells by Heavy Lon Radiotherapy

Dr. Sei Sai, Senior Researcher, Research Center for Charged Particle Therapy, National Institute

of Radiological Sciences, Japan

11:20-11:45 Title: Molecular Control of Neuroblastoma Differentiation

Dr. Hongjuan Cui, Professor, Southwest University, China

11:45-12:10 Title: Cytokines Microenvironment Deplete the Pool of Cancer Stem Cells to Inhibit Androgen

Page 6: Regenerative Medicine & Stem Cells-2013pic.biodiscover.com/files/3/h9/biodiscover1381490091... · 2013-10-11 · 11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

Independent Prostate Cancer

Dr. Wei Chen, Attending Doctor, Urology Department of Zhongshan Hospital, Fudan University,

China

Session 2-5: Induced Pluripotent Stem Cells (iPS) and Cellular Machinery, Cell Responses & Controlling

Time: 15:35-17:20, October 13, 2013 (Sunday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Vi Chu, R & D Manager, Merck-Millipore Corporation, USA

15:35-15:40 Chair’s Introduction

15:40-16:00 Title: PluriSTEM: Weekend & Holiday Free Culture of Pluripotent Human ES/iPS Cells

Dr. Vi Chu, R & D Manager, Merck-Millipore Corporation, USA

16:00-16:20 Title: CD133 Functions in Cell Survival

Dr. Zhong Li, Professor, The Second Military Medical University, China; Director, The 10th

Shanghai People’s Hospital, Tongji University, China

16:20-16:40 Title: ASCT Ips Generated from Blood Cells in a Natural Microenvironment for Clinical

Application

Mr. Hsou-Hsiung Pai, Consultant, Autologous Stem Cell Technology Pty. Ltd., Australia

16:40-17:00 Title: Hepatic Stem Cells; Heterogeneity and Control Mechanisms in Relation to Fibrosis

Dr. Nahed Baddour, Professor of Pathology, Alexandria Faculty of Medicine, Egypt

17:00-17:20 Title: Induced Pluripotent Stem Cells from ALS Patients

Dr. Min Deng, Assistant Researcher, Peking University Third Hospital, China

Session 2-6: Stem Cell & Tissue Development and Adult Stem Cell Research

Time: 08:30-10:55, October 14, 2013 (Monday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Rich Allsopp, Associate Professor, John A Burns School of Medicine, University of Hawaii,

USA

08:30-08:35 Chair’s Introduction

08:35-09:00 Title: The Gene Simplet is a Regulator of Canonical Wnt Signaling in Progenitor Cells of Growing

Appendages, Regenerating Bone and Developing Embryos

Dr. Christopher Antos, Group Leader, DFG-Center for Regenerative Therapies Dresden

(CRTD), Technisch Universitat Dresden, Germany

09:00-09:25 Title: Hypoxia Mediate Regulation of Telomerase in Stem Cells

Dr. Rich Allsopp, Associate Professor, John A Burns School of Medicine, University of Hawaii,

USA

09:25-09:50 Title: Notch Signaling Controls Germline Stem Cell Competitiveness for Niche Occupancy

Dr. Hweijan Hsu, Assistant Professor, Institute of Cellular and Organismic Biology, Academia

Sinica, Taiwan

09:50-10:15 Title: Spermatogonial Stem Cells: A Novel Source of Pluripotent Stem Cells for Regenerative

Medicine

Dr. Yingji Wu, Professor, Inner Mongolia University, China

10:15-10:30 Coffee Break

10:30-10:55 Title: The Role of Endogenous Stem Cells and Progenitor Cells in the Pathogenesis of

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Myelosuppression, Pneumofibrosis and Diabetes

Dr. Evgenii G. Skurikhin, Chief of Research Team, Laboratory of Pathological Physiology and

Experimental Therapy, Institute of Pharmacology of RAMS SD, Russia

Track 3: Basic Sciences and Novel Technologies of Regenerative Medicin

Session 3-1: Cell Culture Technology, Bioreactor, Scaffolds, Biomaterials and Tissue Engineering

Construction

Time: 13:30-17:00, October 12, 2013 (Saturday); Place: Room No. 619, 6th Floor, DICC

Chair Dr. Michel Spina, Professor, University of Padova, Italy

Co-Chair Dr. Raúl Rosales Ibáñez, Research-Professor, Universidad Autonoma De San Luis Potosi,

Mexico

13:30-13:35 Chair’s Introduction

13:35-14:05 Title: Actual Biocompatibility Problems of Current Bioprosthetic Materials and Devices for Heart

Valve Replacement

Dr. Michel Spina, Professor, University of Padova, Italy

14:05-14:35 Title: Biodegradable and Electrically Conducting Polymers: Synthesis and Scaffold Design

Dr. Baolin Guo, Group Leader, Center for Biomedical Engineering and Regenerative Medicine,

Xi’an Jiaotong University, China

14:35-15:05 Title: Self Assembling Peptide Modified Demineralized Bone Matrix as a Scaffold for Enriching

Bone Marrow Promotes Bone Formation

Dr. Jianzhong Xu, Professor; Director, National and Local United Engineering laboratory of

Tissue Engineering, Southwest Hospital, The Third Military Medical University, China

15:05-15:30 Coffee Break

15:30-16:00 Title: Fifth Element of Tissue Engineering: In Situ Applications

Dr. Raul Rosales Ibanez, Research-Professor, Universidad Autonoma De San Luis Potosi,

Mexico

16:00-16:30 Title: Human Embryonic Stem Cells Established from Discarded Embryos and Passaged by

Chemical or Mechanical Methods for Bulk hESCs Expansion

Dr. Ying Liu, Associate Professor, Beijing Obstetrics and Gynecology Hospital, The Capital

University of Medical Science, China

16:30-17:00 Title: Quantenary Chiosan Salt Based Self Assemble Polyelectrolyte and Hybrid Gel as Soft

Contact Lens for Potential Biomedical Application

Dr. Xia Huang, Postdoctor, The university of Michigany, USA

Session 3-2: Cancer Stem Cell (Part Two)

Time: 13:30-15:15, October 13, 2013 (Sunday); Place: Room No. 621, 6th Floor, DICC

Chair Dr. Shuen-Kuei Liao, Chief Scientific Officer, Vectorite Biomedica Inc., Taiwan; Visiting

Professor, Taipei Medical University, Taiwan

13:30-13:35 Chair’s Introduction

13:35-14:00 Title: Targeting Cancer Stem Cells with Withaffirin a Via Inhibition of Induction of

CXCR4-Positive Metastatic Cancer Stem Cells and STAT3 Phosphorylation

Page 8: Regenerative Medicine & Stem Cells-2013pic.biodiscover.com/files/3/h9/biodiscover1381490091... · 2013-10-11 · 11:00-11:25 Title: Stem Cells, Stem Cell Niche and Organ Regeneration

Dr. Shuen-Kuei Liao, Chief Scientific Officer, Vectorite Biomedica Inc., Taiwan; Visiting

Professor, Taipei Medical University, Taiwan

14:00-14:25 Title: Applications of Theoretical Computer Science in Cancer Stem Cell Research

Mr. Andrew Ninh, CEO, President, Co-Founder, ScheiNinh LLC, USA

14:25-14:50 Title: The Speculation and Discussion of the Application Management ofRegeneration Medicine

and Cell Therapy Technology in China

Hu Bo, Broad Chairman, Ciming Medical Group-Oasis Wellness Club Life Medical Center;

Deputy Director, Secretary-General, Committee for Medical Technology Administration of the

Chinese Hospital Association (MTA), China

14:50-15:15 Title: Targeting PI3K in Breast Cancer

Dr. Pixu Liu, Professor, Institute of Cancer Stem Cell, Dalian Medical University, China

Session 3-3: Growth Factors and Morphogens in Regenerative Medicine

Time: 15:30-17:15, October 13, 2013 (Sunday); Place: Room No. 621, 6th Floor, DICC

Chair Dr. Richard G. LeBaron, Associate Professor, University of Texas at San Antonio, USA

15:30-15:35 Chair’s Introduction

15:35-16:00 Title: Extracellular Matrix, Growth Factors and Morphogens: Promise of Tissue Regeneration

Accentuation

Dr. Richard G. LeBaron, Associate Professor, University of Texas at San Antonio, USA

16:00-16:25 Title: Molecular Pathways in VEGF-Induced Angiogenesis and Vascular Regeneration

Dr. Zheng Gen Jin, Associate Professor, University of Rochester School of Medicine, USA

16:25-16:50 Title: Neuropeptide SP Activates WNT Signal Transduction Pathway and Enhances the

Proliferation of Bone Marrow Stromal Stem Cells

Dr. Dan Jin, Professor; Chief Physician, Nangfang Hospitol, China

16:50-17:15 Title: Role of VEGF in Bone Formation

Dr. Yanqi Yang, Assistant Professor, The University of Hong Kong, Hong Kong, China

Session 3-4: Immunity Research and Regeneration Medicine

Time: 10:55-12:00, October 14, 2013 (Monday); Place: Room No. 618, 6th Floor, DICC

Chair Dr. Hans-Dieter Volk, Full Professor of Immunology, Director, Institute of Medical Immunology &

Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin

Berlin, Germany

10:55-11:00 Chair’s Introduction

11:00-11:30 Title: The Negative Co-Stimulatory Molecules Expressed on Mesenchymal Stem Cells and

Mediate Their Immuno-Modulating Effect on T Cells

Dr. Qun Xue, Chief Physician, Neurology Department of the First Affiliated Hospital of Soochow

University, China

11:30-12:00 Title: Adoptive T Reg/Eff Cell Therapy to Regenerate‖ Protective Immunity after Transplantation

Dr. Petra Reinke, Medical Director; Head of the ―Kidney Transplant Outpatient Clinic‖; Head of

the GMP-Facility, Charité-Universitätsmedizin Berlin, Charité Campus Virchow-Klinikum,

Germany

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Session 3-5: Novel Technology in Regeneration Medicine: Nanotechnology, Imaging, Modelling and

Monitoring

Time: 08:30-10:15, October 14, 2013 (Monday); Place: Room No. 619, 6th Floor, DICC

Chair Dr. George Altankov, ICREA Research Professor, Institute for Bioengineering of Catalonia,

Spain

08:30-08:35 Chair’s Introduction

08:35-09:00 Title: Fluorescent Nanodiamonds Enable in vivo Tracking of Prospectively Isolated Lung Stem

Cells

Dr. John Yu, Distinguished Research Fellow, Institute of Cellular & Organismic Biology and the

Genomics Research Center, Academia Sinica, Taiwan

09:00-09:25 Title: Nanofibres Design for Guided Cellular Behaviour

Dr. George Altankov, ICREA Research Professor, Institute for Bioengineering of Catalonia,

Spain

09:25-09:50 Title: High Speed, High Content Multi-Spectral Cellular Imaging in Flow Cytometry, Novel

Technology for Research Strategies in Regenerative & Stem Cell Research

Mr. George McBride, Senior Regional Field Applications Manager, Cellular Analysis–Asia,

Merck Millipore Bioscience Division of Merck KGaA, Singapore

09:50-10:15 Title: Nanoscale Architectures for Controlling Cellular Mechanoresponse

Dr. Shalom J. Wind, Senior Research Scientist/Professor, Columbia University, USA

10:15-10:30 Coffee Break

Track 4: Clinical Translations of Regenerative Therapy

Session 4-1: Angiogenesis and Cardiac Tissue Repair

Time: 13:30-17:10, October 12, 2013 (Saturday); Place: Room No. 620, 6th Floor, DICC

Chair Dr. Philippe Henon, Director, Research Institute of Hematology and Transplantation, Universite

de Haute Alsace, France

Co-Chair Dr. Austin Guo, Assistant Professor, New York Medical College, USA

13:30-13:35 Chair’s Introduction

13:35-14:00 Title: Discovery of Novel Molecules for in situ Cardiac Regeneration

Dr. Qingdong Wang, Leader of Regenerative Medicine Innovation Team, AstraZeneca R & D

Mölndal, Sweden

14:00-14:25 Title: Academic to Industry Translation in CD34+ Cell Therapy for Treatment of Acute Myocardial

Infarct (AMI): A Long Obstacle Race

Dr. Philippe Henon, Director, Research Institute of Hematology and Transplantation, Universite

de Haute Alsace, France

14:25-14:50 Title: Cardiac Stem/Progenitor Cells: Cardiac Side Population Cells

Dr. Simon X. Liang, Head and Professor, Department of Biochemistry and Molecular Biology,

Liaoning Medical University, China

14:50-15:15 Title: Application of Stem Cells and Reprogrammed Cardiomyocytes in Myocardial Regeneration

Dr. Xiaowen Bai, Assistant Professor, Medical College of Wisconsin, USA

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15:15-15:30 Coffee Break

15:30-15:55 Title: 20-HETE Regulates Angiogenic Functions of Human Endothelial Progenitor Cells

Dr. Austin Guo, Assistant Professor, New York Medical College, USA

15:55-16:20 Title: The Tandem Telocytes & Stem Cells vs. the Stem-Cell Dogma in Cardiac Repair

Dr. Lawrence M. Popescu, Professor of Cellular and Molecular Medicine, University of Medicine

and Pharmacy, Romania; Head, the National Institute of Pathology, Romania

16:20-16:45 Title: NADPH Oxidase Derived ROS Signalling in Angiogenesis

Dr. Hitesh M Peshavariya, Research Fellow, Centre for Eye Research Australia, University of

Melbourne, Australia

16:45-17:10 Panel Discussion

Session 4-2: Neural Degenerative Diseases, Stroke and CNS Repairing

Time: 13:30-17:10, October 12, 2013 (Saturday); Place: Room No. 621, 6th Floor, DICC

Chair Dr. Sha Mi, Distinguished Investigator in Discovery Neurobiology, Biogen Idec, USA

Co-Chair Dr. Alex Kharazi, Chief Technology Officer, Stemedica Cell Technologies, USA

13:30-13:35 Chair’s Introduction

13:35-14:00 Title: Blocking the LINGO-1 Pathway as a Novel Therapeutic Approach for CNS Repair

Dr. Sha Mi, Distinguished Investigator in Discovery Neurobiology, Biogen Idec, USA

14:00-14:25 Title: Neural Signal Regeneration and Motor Function Rebuilding of Paralyzed Limbs. Based on

Principles of Communication and Functional Electrical Stimulation

Dr. Zhigong Wang, Professor, Institute of RF- & OE-ICs Southeast University, China

14:25-14:50 Title: Promote Axon Regeneration and Functional Recovery after CNS Injury

Dr. Shuxin Li, Associate Professor, Shriners Hospitals Pediatric Research Center, Temple

University School of Medicine, USA

14:50-15:15 Title: Involuntary Muscle Spasm Expressed as Motor Evoked Potential after Olfactory Mucosa

Autograft in Patients with Chronic Spinal Cord Injury and Complete Paraplegia

Dr. Koichi Iwatsuki, Associate Professor, Osaka University Medical School, Japan

15:15-15:30 Coffee Break

15:30-15:55 Title: Human Mesenchymal Stem Cells for the Treatment of Stroke

Dr. Alex Kharazi, Chief Technology Officer, Stemedica Cell Technologies, USA

15:55-16:20 Title: Efficacy of Stem Cell Therapy in Cerebral Palsy

Dr. Anant Bagul, Director, Chaitanya Hospital & Stem Cell Center, India

16:20-16:45 Title: Bio Modulation of Autologus Bone Marrow –A New Treatment Strategy in Chronic Spinal

Cord Injury.

Dr. PS John, Head, Department of Regenerative Medicine, St. Thomas Hospital, India

16:45-17:10 Title: Cell Therapy for Perinatal Cerebral Injury — From Basic Research to Clinical Trial

Dr. Zuo Luan, Chief Physician, Department of Pediatrics, Navy General Hospital, China

Session 4-3: Repair and Regeneration of Oral and Craniofacial Tissues

Time: 08:30-12:00, October 13, 2013 (Sunday); Place: Room No. 619, 6th Floor, DICC

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Chair Dr. Wolf-Dieter Grimm, Professor of Periodontology, University of Witten/Herdecke, Germany

Co-Chair Dr. Shuying Yang, Assistant Professor, The State University of New York, USA

08:30-08:35 Chair’s Introduction

08:35-09:05 Title: Use of Stem-Cell Induced Allogenic Bonerings® for Pre-Implantological Vertical

Augmentations of Alveolar Bone Defects in Humans-A Clinical Controlled Study

Dr. Wolf-Dieter Grimm, Professor of Periodontology, University of Witten/Herdecke, Germany

09:05-09:35 Title: Dentin Regeneration on Exposed Dental Pulp by Phosphophoryn-Derived RGD Peptide

Dr. Takashi Saito, Professor, Health Sciences University of Hokkaido, Japan

09:35-10:05 Title: Estrogen-mediated Differentiation of Adult Dental Stem Cells

Dr. Jinhua Yu, Associate Director, Institute of Stomatology, Nanjing Medical University, China

10:05-10:30 Coffee Break

10:30-11:00 Title: Gene and Stem Cell Based Vascularized Bone Regeneration for Critical-sized Bone Defect

Dr. Shuying Yang, Assistant Professor, The State University of New York, USA

11:00-11:30 Title: Bio Engineering Bone Parts. Application in Dentistry and in Periodontology

Dr. S. Sankaranarayanan, Director, Mothercell Regenerative Centre, India

11:30-12:00 Title: Enhancing Bone Vascularization towards Regeneration after Cancer Ablation

Dr. Ahmad Eweida, Assistant Lecturer, Alexandria University, Egypt

Session 4-4: Digestive Respiratory and Urologic Tissues and Organ Regeneration

Time: 08:30-10:30, October 13, 2013 (Sunday); Place: Room No. 620, 6th Floor, DICC

Chair Dr. Very Coulic, Professor and Researcher, CHU Brugmann, ULB, Experimental Medicine

Laboratory, Belgium

Co-Chair Dr. Ena Ray Banerjee, Associate Professor, University of Calcutta, India

08:30-08:35 Chair’s Introduction

08:35-08:55 Title: Fetal Organ Transplantation as a Step in Regenerative Medicine

Dr. Very Coulic, Professor and Researcher, CHU Brugmann, ULB, Experimental Medicine

Laboratory, Belgium

08:55-09:15 Title: Novel Regenerative Treatment of Male Stress Urinary Incontinence by Periurethral

Injection of Autologous Adipose-Derived Regenerative Cells: 1-Year Outcomes in 11 Patients

Dr. Tokunori Yamamoto, Associate Professor, Nagoya University, Japan

09:15-09:35 Title: Kidney Regeneration by Non-Platelet RNA-Containing Particle-Derived Cells

Dr. Wuyi Kong, Director, Beijing Khasar Medical Technology Co., China

09:35-09:55 Title: Human Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Prevent Allergic Airway

Inflammation

Dr. Qingling Fu, Associate Professor, Otorhinolaryngology Hospital, The First Affiliated Hospital,

Sun Yat-sen University, China

09:55-10:15 Title: Looking for the Elusive Lung Stem Cell Niche

Dr. Ena Ray Banerjee, Associate Professor, University of Calcutta, India

10:15-10:30 Coffee Break

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Session 4-5: Bone and Cartilage Tissue Repairing

Time: 10:30-12:15, October 13, 2013 (Sunday); Place: Room No. 620, 6th Floor, DICC

Chair Dr. Kwan Hee Lee, Chief Medical Officer, TissueGene, Inc., USA

10:30-10:35 Chair’s Introduction

10:35-11:00 Keynote Speech:

Title: Clinical Applications of Mesenchymal Stem Cells in the Treatment of Fracture Non-Union,

Bone Defects and Osteonecrosis

Dr. Stefano Zanasi, Professor, University of Florence, Italy

11:00-11:25 Title: Clinical Development of Cell and Gene Therapy for Cartilage Regeneration in Severe

Osteoarthritis Patients

Dr. Kwan Hee Lee, Chief Medical Officer, TissueGene, Inc., USA

11:25-11:50 Title: Effect of G-CSF on Neovascularization and Osteogenesis in Aged Osteoporotic Bone

Dr. Liwu Zheng, Clinical Assistant Professor, The University of Hong Kong, Hong Kong, China

11:50-12:15 Title: Tissue Engineering Cartilage Repair Articular Cartilage Injury-----From Basic to Clinicall

Dr. Quanyi Guo, Professor, Institute of Orthopedic Research, General Hospital of the People's

Liberation Army, China

Session 4-6: Musculoskeletal Tissue Regeneration and Wounded Skin Repair

Time: 13:30-15:15, October 13, 2013 (Sunday); Place: Room No. 619, 6th Floor, DICC

Chair Dr. Redha Taiar, Professor, University of Reims Champaign, France

Co-Chair Dr. Marco Brotto, Endowed Professor of Nursing & Medicine, Director of the Muscle Biology

Research Group, University of Missouri-Kansas City, USA

13:30-13:35 Chair’s Introduction

13:35-14:00 Title: Simulation and Modelization of the Human Body: New Perspectives

Dr. Redha Taiar, Professor, University of Reims Champaign, France

14:00-14:25 Title: Targeting the DNA Damage Response Pathways in the Repair of Acute Thermal and

Ultraviolet Light Injury

Dr. Madalene C. Y. Heng, Professor, UCLA School of Medicine/Dermatology, USA

14:25-14:50 Title: Bone-Muscle Crosstalk: New Insights into Myogenesis and Muscle Function-New Ideas for

Muscle Regeneration?

Dr. Marco Brotto, Endowed Professor of Nursing & Medicine, Director of the Muscle Biology

Research Group, University of Missouri-Kansas City, USA

14:50-15:15 Title: Regulation Mechanism of Wnt Signaling Pathway Involved in the Differentiation of Hair

Follicle Stem Cells Induced by Lithium Chloride

Dr. Bin Yang, Professor, Plastic Surgery Hospital (Institute), Chinese Academy of Medical

Sciences, China

15:15-15:30 Coffee Break

Session 4-7: Anti-aging & Cosmetology and Regenerative Medicine

Time: 15:30-17:15, October 13, 2013 (Sunday); Place: Room No. 619, 6th Floor, DICC

Chair Dr. Qizhi Chen, Reader, Monash University, Australia

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15:30-15:35 Chair’s Introduction

15:35-15:55 Title: Delivering Stem Cells to Treat Diseased Soft Organs using Elastomeric Biomaterials

Dr. Qizhi Chen, Reader, Monash University, Australia

15:55-16:15 Title: Restorative Technology in Hair Transplant: Case of ACell Use at myWHTC

Dr. Patrick Mwamba, Medical Director, World Hair Transplant Center, Belgium

16:15-16:35 Title: Osteoplastic Surgery of the Face As a Regenerative and Restorative Surgical Procedure in

Aesthetic and Plastic-Reconstructive Surgery

Dr. Kurt Vinzenz, Director of Oral and Maxillofacial Surgery, Evangelisches Krankenhaus

Wien, Vienna University, Austria

16:35-16:55 Title: Cellular and Molecular Regulation of New Insulin-Producing Cells from Duct Progenitors

during Pancreas Regeneration

Dr. Wan-Chun Li, Assistant Professor, Department of Dentistry & Institute of Oral Biology,

National Yang-Ming University, Taiwan

16:55-17:15 Title: The Role of Regenerative Medicine in Rejuvenation

Dr. Yuan-Sung Kuo, Clinical Assistant Professor, College of Medicine, National Taiwan

University, Taiwan

Session 4-8: Stem Cell Therapy for Disease and Artificial Organ

Time: 08:30-12:10, October 14, 2013 (Monday); Place: Room No. 620, 6th Floor, DICC

Chair Dr. Alain Chapel, Principal Investigator, Institute of Radioprotection and Nuclear Safety (IRSN),

France

08:30-08:35 Chair’s Introduction

08:35-09:00 Title: Human Stem Cell Therapy for the Treatment of Radiation - Induced Normal Tissue

Damage

Dr. Alain Chapel, Principal Investigator, Institute of Radioprotection and Nuclear Safety (IRSN),

France

09:00-09:25 Title: Nonhuman Primate Disease Model Applications for Stem Cell-based Efficacy Evaluation

Dr. Rosario M. Perez, Director, Maccine Pte Ltd., Singapore

09:25-09:50 Title: Hepatic Regenerative Potential of Mouse Bone Marrow very Small Embryonic-Like Stem

Cells

Dr. Gangming Zou, Professor, Shanghai Jiao Tong University, China

09:50-10:15 Title: Fetal Progenitor Cells and Cord Blood Stem Cells in Complex Treatment of Chronic Limb

Ischemia, Pancreonecrosis and Chronic Wounds: Clinical Trials Results

Dr. Oleksandr Kukharchuk, Research Director, EmProCell Clinical Research Pvt. Ltd., India

10:15-10:30 Coffee Break

10:30-10:55 Title: Regenerative Medicine in Orthopedics

Dr. V. R. Ravi, Director, Mothercell Regenerative Centre, India

10:55-11:20 Title: BMSC Transplantation Treating Acute Liver Failure in Rat Model

Dr. Yue-Xin Zhang, Professor, First Affiliated Hospital, Xinjiang Medical University, China

11:20-11:45 Title: Donor Chimera Model for Tolerance Induction in Transplantation

Dr. Monireh Dashty, Medical Doctor and Biologist, University of Groningen, The Netherlands

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11:45-12:10 Panel Discussion

Track 5: Young Scientist Research

Session 5-1: Young Scientist Research

Time: 10:55-11:50, October 14, 2013 (Monday); Place: Room No. 619, 6th Floor, DICC

Chair Dr. Hans-Peter Deigner, Professor, Furtwangen University, Germany

10:30-10:35 Chair’s Introduction

10:35-11:00 Title: Evaluation of Glioma-targeting Capacity of Human Umbilical Cord Derived Mesenchymal

Stem Cells in vivo

Dr. Cungang Fan, Attending Neurosurgeon; Principle Investigator of Glioma Specialty; Head of

Bio-Bank in the Neurosurgical Department, Peking University People’s Hospital, China

11:00-11:25 Title: Novel Aspect on Regulatory T Cells-A New Cellular Source for Cell Therapy

Dr. Hong Lei, Ph.D. Candidate, Berlin-Brandenburg Center for Regenerative Therapies, Charite

University Medicine Berlin, Germany

11:25-11:50 Title: Characterisation of 3D Organotypic Cultures of H400 and Primary Rat Keratinocytes

Dr. Erum Khan, School of Dentistry, University of Birmingham, UK

Chinese Scientist Forum (Language: Mandarine)

Chinese Scientist Forum (Language: Mandarine)

Time: 13:30-17:10, October 13, 2013 (Sunday); Place: Room No. 620, 6th Floor, DICC

Chair Dr. Chunmeng Jiang, Director, Gastroenterology Department of the Second Affiliated Hospital

of Dalian Medical University, China

13:30-13:35 Chair’s Introduction

13:35-13:55 Title: Clinical Research of Autologous Transplantation of Bone Marrow Stem Cells on

Decompensate Cirrhosis Patients

Dr. Chunmeng Jiang, Director, Gastroenterology Department of the Second Affiliated Hospital

of Dalian Medical University, China

13:55-14:15 Title: The Cilinical Therapeutic Effects of Human Umbilical Cord Mesenchymal Stem Cell

Transplantation in Treatment of End Stage Liver Disease

Weizheng Zeng, Professor and Chief Physician, Chengdu Military General Hospital, China

14:15-14:35 Title: A GATA-4 Target, EGF, Regulates Cell Proliferation and Differentiation by Modulating the

Cell Cycle Regulatory Protein Cyclin D1

Mingxi Zang, Associate Professor, Zhenzhou University, China

14:35-14:55 Title: Preliminary Protection of Oleanolic Acid Attenuates Neural Stem Cells Differentiation into

Astrocytes through JAK/STAT Signaling Pathway

Dr. Yulian Zhang, Subdecanal and Archiater, The Second Affiliated Hospital of Tianjin Medical

University, China

14:55-15:15 Title: Shear Stress-Induced Activation of Tie2-Dependent Signaling Pathway Enhances in Vivo

Reendothelialization Capacity of Human Endothelial Progenitor Cells

Dr. Zhen Yang, Associate Professor, The First Affiliated Hospital of Sun Yat-Sen University,

China

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15:15-15:30 Coffee Break

15:30-15:50 Title: Autologous Peripheral Blood Stem Cells Transplantation for the Treatment of Diabetic

Vascular Disorder in Lower Extremities

Hua Li, Attending Doctor, The Second Hospital of Xiamen, China

15:50-16:10 Title: Human Mesenchymal Stem Cells and Tumor Growth

Dr. Juan Liu, Resident Physician, Provincial Hospital Affiliated to Shandong University, China

16:10-16:30 Title: Safety and Efficacy Evaluation of a Human Acellular Nerve Graft as a Digital Nerve

Scaffold: A Prospecti Ve, Multicentre Controlled Clinical Trial

Dr. Bo He, Attending Physician, The First Affiliated Hospital, Sun Yat-sen University, China

16:30-16:50 Title: Adipose-Derived Stem Cells Improved Mouse Ovaryfunction after Chemotherapy-Induced

Ovary Failure

Dr. Min Sun, Ph.D. Candidate, Fourth Military Medical University, China

16:50-17:10 Title: Generation of Knockout/inMouse Models Using Novel Custom Endonuclease Technologies

Dr. Steve X. Yu, Director of Technology, Cyagen Biosciences, Inc., USA/China