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31
-2 -1 0 1 2 Control Treatment Sample Beta Score Negative control normalized -2 -1 0 1 2 Control Treatment Sample Beta Score Cell cycle normalized 0.0 0.5 1.0 1.5 -2 -1 0 1 2 Beta Score Density Control Treatment Negative control normalized 0.0 0.5 1.0 1.5 2.0 -2 -1 0 1 2 Beta Score Density Control Treatment Cell cycle normalized

R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

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Page 1: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

−2

−1

0

1

2

Control

Treatment

Sample

Bet

a S

core

Negative control normalized

−2

−1

0

1

2

Control

Treatment

Sample

Bet

a S

core

Cell cycle normalized

0.0

0.5

1.0

1.5

−2 −1 0 1 2

Beta Score

Den

sity

Control

Treatment

Negative control normalized

0.0

0.5

1.0

1.5

2.0

−2 −1 0 1 2

Beta Score

Den

sity

Control

Treatment

Cell cycle normalized

Page 2: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

0

1

2

3

4

−1.0 −0.5 0.0 0.5 1.0 1.5

Treat−Control Beta Score

Den

sity

Negative control normalized

0

1

2

3

4

−0.5 0.0 0.5 1.0

Treat−Control Beta Score

Den

sity

Cell cycle normalized

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●

−2 −1 0 1 2

−0.

50.

51.

0

Cell cycle normalized

A

M

Median: 0.00322IQR: 0.122

Page 3: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

−2

−1

0

Control

Treatment

Sample

Ess

entia

l.B.S

.Negative control normalized

−2.0

−1.5

−1.0

−0.5

0.0

0.5

Control

Treatment

Sample

Ess

entia

l.B.S

.

Cell cycle normalized

0.00

0.25

0.50

0.75

1.00

−2 −1 0

Essential.B.S.

Den

sity

Control

Treatment

Negative control normalized

0.0

0.3

0.6

0.9

1.2

−2.0 −1.5 −1.0 −0.5 0.0 0.5

Essential.B.S.

Den

sity

Control

Treatment

Cell cycle normalized

Page 4: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

−2

−1

0

1

2

−2 −1 0 1 2

Control

Bet

a S

core

Control

Treatment

Negative control normalized

−2

−1

0

1

2

−1 0 1 2

Control

Bet

a S

core

Control

Treatment

Cell cycle normalized

−2

−1

0

−2 −1 0

Control

Ess

entia

l.B.S

.

Control

Treatment

Negative control normalized

−2.0

−1.5

−1.0

−0.5

0.0

0.5

−1.5 −1.0 −0.5 0.0 0.5

Control

Ess

entia

l.B.S

.

Control

Treatment

Cell cycle normalized

Page 5: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

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GroupA: 3138

GroupB: 2143−2

−1

0

1

2

−2 −1 0 1 2

Control beta.score

Trea

tmen

t bet

a.sc

ore

Negative control normalized

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GroupA: 2813

GroupB: 2471−2

−1

0

1

2

−1 0 1 2

Control beta.score

Trea

tmen

t bet

a.sc

ore

Cell cycle normalized

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SLC35E2

UBE2M CUL3

CFC1

NF1

SLC35E2B

GADD45GIP1

SULT1A2

TADA1

POP7

OR52E2

MED12

ITGB2

CCL21

ORM1

NF2

KLF5

TADA2B

NOTCH2MCL1

0

5000

10000

15000

−0.5 0.0 0.5 1.0 1.5

Treatment−Control Beta Score

Ran

k

Negative control normalized

●

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PDCL2

IFI27L1

SLC35E2

UBE2MMETTL2B

CUL3

CFC1

NF1

GADD45GIP1

SULT1A2

ZSWIM1

TADA1

OR52E2

MED12ZBTB11

ORM1

NF2

KLF5TADA2B

MCL1

0

5000

10000

15000

−0.5 0.0 0.5 1.0

Treatment−Control Beta Score

Ran

k

Cell cycle normalized

Page 6: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

●NANA

6.25 6.50 6.75 7.00

−log10(Adjust.pvalue)

Count ● 26

KEGG: GroupA

●NANA

5.8 6.0 6.2 6.4 6.6

−log10(Adjust.pvalue)

Count ● 48

KEGG: GroupA

●●●●

●●●●●●

●●

●●●●●●●●Iron−sulfur cluster assembly

Regulation of TOR signalingNucleic acid phosphodiester bond hydrolysis

Peptidyl−lysine modificationSRP−dependent cotranslational protein targeting ...

Endosome organizationRegulation of RNA stability

Mitochondrial RNA metabolic processSelenium compound metabolic process

RNA localizationNegative regulation of protein ubiquitinationMitochondrial respiratory chain complex I ...

Mitochondrial respiratory chain complex I assemblyNADH dehydrogenase complex assembly

DNA−templated transcription, initiationDNA−templated transcription, elongation

Cellular respirationMulti−organism metabolic process

Mitochondrial translationNcRNA metabolic process

5 10 15 20

−log10(Adjust.pvalue)

Count ● ● ● ●40 80 120 160

BP: GroupA

●●●●●●●

●●●

●●●●●

●

●

●RNA modificationRegulation of TORC1 signaling

TORC1 signalingMitochondrial RNA metabolic process

Selenium compound metabolic processDNA−templated transcription, initiation

RNA localizationDNA−templated transcription, elongation

Ribosome biogenesisRNA catabolic process

Multi−organism metabolic processMitochondrial respiratory chain complex assembly

Mitochondrial respiratory chain complex I ...Mitochondrial respiratory chain complex I assembly

NADH dehydrogenase complex assemblyCellular respiration

NcRNA metabolic processMitochondrial translation

5 10

−log10(Adjust.pvalue)

Count ● ● ● ● ●25 50 75 100 125

BP: GroupA

Page 7: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

●NANA

1.75 2.00 2.25 2.50

−log10(Adjust.pvalue)

Count ● 66

KEGG: GroupB

No enriched terms

KEGG: GroupB

No enriched terms

BP: GroupB

No enriched terms

BP: GroupB

Page 8: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group A

Negative control normalized

Page 9: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group A

Negative control normalized

Page 10: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No multi pathview figures

Group B

Negative control normalized

Page 11: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No multi pathview figures No multi pathview figures

Group B

Negative control normalized

Page 12: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group A

Cell cycle normalized

Page 13: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group A

Cell cycle normalized

Page 14: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

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514

741

276972

−0.50

−0.25

0.00

0.25

0.50

−0.6 −0.4 −0.2 0.0 0.2 0.4

Control Beta Score

Trea

tmen

t Bet

a S

core

● ● ●

● ●

Group1 Group2 Group3

Group4 Others

Negative control normalized

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517

749

278969

−0.25

0.00

0.25

0.50

−0.4 −0.2 0.0 0.2

Control Beta ScoreTr

eatm

ent B

eta

Sco

re

● ● ●

● ●

Group1 Group2 Group3

Group4 Others

Cell cycle normalized

Page 15: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

●NANA

2.4 2.6 2.8 3.0 3.2

−log10(Adjust.pvalue)

Count ● 20

KEGG: Group1

●NANA

2.6 2.8 3.0 3.2 3.4

−log10(Adjust.pvalue)

Count ● 20

KEGG: Group1

●●

●

●

●●

●Multivesicular body organization

RNA splicing

NcRNA metabolic process

Transcription elongation from RNA polymerase II ...

Mitochondrial RNA metabolic process

RNA localization

Mitochondrial translation

2 4 6 8

−log10(Adjust.pvalue)

Count ● ● ● ●10 20 30 40

BP: Group1

●●

●

●

●●

●Multivesicular body organization

RNA splicing

NcRNA metabolic process

Transcription elongation from RNA polymerase II ...

Mitochondrial RNA metabolic process

RNA localization

Mitochondrial translation

2 4 6 8

−log10(Adjust.pvalue)

Count ● ● ● ●10 20 30 40

BP: Group1

Page 16: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group2

No enriched terms

KEGG: Group2

No enriched terms

BP: Group2

No enriched terms

BP: Group2

Page 17: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group3

No enriched terms

KEGG: Group3

No enriched terms

BP: Group3

No enriched terms

BP: Group3

Page 18: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group4

No enriched terms

KEGG: Group4

No enriched terms

BP: Group4

No enriched terms

BP: Group4

Page 19: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

●NANA

1.0 1.2 1.4 1.6 1.8

−log10(Adjust.pvalue)

Count ● 20

KEGG: Group1&3

●NANA

1.0 1.2 1.4 1.6 1.8

−log10(Adjust.pvalue)

Count ● 20

KEGG: Group1&3

●

●RNA localization

Mitochondrial translation

2 3 4 5 6

−log10(Adjust.pvalue)

Count ● ● ● ● ●29.00 29.25 29.50 29.75 30.00

BP: Group1&3

●

●RNA localization

Mitochondrial translation

2 3 4 5 6

−log10(Adjust.pvalue)

Count ● ● ● ● ●29.00 29.25 29.50 29.75 30.00

BP: Group1&3

Page 20: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group1&4

No enriched terms

KEGG: Group1&4

●Mitochondrial translation

3.6 3.8 4.0 4.2 4.4

−log10(Adjust.pvalue)

Count ● 32

BP: Group1&4

●Mitochondrial translation

3.4 3.6 3.8 4.0 4.2

−log10(Adjust.pvalue)

Count ● 32

BP: Group1&4

Page 21: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group2&3

No enriched terms

KEGG: Group2&3

No enriched terms

BP: Group2&3

No enriched terms

BP: Group2&3

Page 22: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group2&4

No enriched terms

KEGG: Group2&4

No enriched terms

BP: Group2&4

No enriched terms

BP: Group2&4

Page 23: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No enriched terms

KEGG: Group1&2&3&4

No enriched terms

KEGG: Group1&2&3&4

No enriched terms

BP: Group1&2&3&4

No enriched terms

BP: Group1&2&3&4

Page 24: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group 1

Negative control normalized

Page 25: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group 1

Negative control normalized

Page 26: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group 1

Cell cycle normalized

Page 27: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

Group 1

Cell cycle normalized

Page 28: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No multi pathview figures

Group 1 & Group 3

Negative control normalized

Page 29: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No multi pathview figures No multi pathview figures

Group 1 & Group 3

Negative control normalized

Page 30: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No multi pathview figures

Group 1 & Group 3

Cell cycle normalized

Page 31: R Graphics Outputcistrome.org/MAGeCKFlute/demo/MAGeCKFlute/FluteMLE/... · 2018. 4. 24. · TADA1 POP7 OR52E2 MED12 ITGB2 CCL21 ORM1 NF2 KLF5 TADA2B MCL1 NOTCH2 0 5000 10000 15000

No multi pathview figures No multi pathview figures

Group 1 & Group 3

Cell cycle normalized


슬라이드 1 - cadgraphics.co.kr · CAE PKG Warpage -r CCL21 simulation ... You have to run this script in ANSYS Workbench to complete the export process ... Ansys WB . CAE

슬라이드 1 - cadgraphics.co.kr · CAE PKG Warpage -r CCL21 simulation ... You have to run this script in ANSYS Workbench to complete the export process ... Ansys WB . CAE

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