QuattroMix Single Use Mixing System For Single Use Bag
Integration work In cooperation with:
Slide 2
QuattroMix Principles Application: Design 16 outlet nozzles
Single Use Bag Theoretical fluid stream Connected with pump in- and
outlet Exocirculation Via pump Random Vector No Vortexing
Slide 3
Performance test 500L Solid/liquid mixing performance: Addition
of NaCl to 500L Water 4g/l Completely dissolved after 10 min 2g/l;
Completely dissolved after 5 min 500L bag with two QuattroMixers,
in parallel connected to one QF1200SU.
Slide 4
Applications Typical application in biopharmaceutical processes
Buffer preparation Media preparation Virus inactivation And others
Salts Purified Water Acids/ Bases Carbohydrates Nutrients SU Bag
with Mixer Sterile Filtration Upstream or Downstream Process
Slide 5
QuattroMix Enables: Quattroflow Pump becomes a multi purpose
device, because Recirculation of liquid is used for mixing effect
Can be used for filling and emptying of the bag Can be used for
post-mixing processes, like sterile filtration, virus filtration,
flow through chromatography, etc. Recirculation loop allows for
additional features like Integration of in-line sensors (pH,
conductivity, temperature, UV) Usage of heat exchanger for
cooling/heating of media Filter Filtrated Product Heat exchanger
TIR Feedstock
Slide 6
JetMixer Solid/liquid mixing performance: Addition of 500 g
NaCl to 200L Water Result: Better performance of QF mixer Still
undissolved NaCl after 18 minCompletely dissolved after 4 min
Comparison 200L
Slide 7
Performance test JetMixer Liquid/liquid mixing performance:
adding 100 g predesolved NaCl to 200L Water Result: Comparable
mixing performance:
Slide 8
Comparison 200L JetMixer QuattroMix
Slide 9
Available For: Application development work Mixing problem
resolution Bag Sizes: 100L, 200L with single mixer 500L with dual
mixer Bag Configuration/porting On request to HPNE From: HPNE