Pyelonephritis (Final Case)

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    PYELONEPHRITISGROUP 1

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    I. INTRODUCTION

    The diagnosis of a urinary tract infection (UTI) istypically confirmed on the basis of a certain numberof microorganisms in the urinary system, althoughmanifestation may begin with many fewer

    organisms. The infectious process usually affectsthe bladder, but the uretrhra, ureters, and kidneymay be involved.

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    Urinary tract infection (UTI) is one of the mostcommon infection treated by primary careproviders, untreated, it has the potential for seriousconsequence, such as pyelonephritis and

    bacteremia. On rare occasions, complication of UTIcan lead death. Cystisis is the most common typesof UTI.

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    DEFINITION:

    CYSTITIS

    Inflammation of the urinary bladder

    s/sx:

    Pressure in lower pelvis Painful urination (dysuria)

    Frequent urination(polyuria)

    Abnormal urine color(cloudy)

    Foul odor of urine

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    -URETHRITIS

    inflammation of the urethra.

    s/sx:

    Dysuria

    Painful urination

    -URETERITIS

    Inflammation of the ureter.

    s/sx:

    Renal colic

    Fever

    Blood in the urine

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    PYELONEPHRITIS

    Inflammation of renalpelvis.

    s/sx:

    Acutely ill with chills andfever

    High fever and chills

    Leukocytosis

    Bacteriuria

    Dysuria

    Flank pain

    CVA tenderness

    Nausea

    Foul smelling urine

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    CAUSES:

    Pyelonephritis is caused by Escherichia coli this isa type of bacteria that normally in the largeintestine. However, any physical obstruction to theflow of urine, such as structural abnormality,

    bladder tumor, strictures, kidney stone or anenlarged prostrate or backflow (reflux) of urine fromthe bladder into the ureters may causepyelonephritis

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    PREVALENCE RATE:

    EPIDEMIOLOGY:

    -Pyelonephritis is very common, with 12-13 casesannually per 10,000 populations in women and 3-4cases per 10,000 in men. Young women are mostlikely to be affected, traditionally affecting sexualactivity in that age group. Infants and the elderly arealso at increase risk, reflecting anatomical changesand hormonal status.

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    6 years of age;

    Boys: 1.8% Girls: 6.6%

    5-7% Female febrile infant (8 weeks of age)

    1% School-age children 1-3% Girl between 1-5 years of age

    0.003% School age boys

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    DIAGNOSIS:

    The presence of nitrite and leukocyte (white bloodcell) on a urine dipstick test in patients with typicalsymptoms are sufficient for the diagnosis ofpyelonephritis, and are an indication for empirical

    treatment. Formal diagnosis is with culture of theurine blood cultures may be needed if the source ofthe infection is initially doubtful.

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    II.NURSING HISTORY

    PATIENTS PROFILE

    Name: Ms. Yuri

    Age:21

    Sex: Female

    Address: P2 Dubinan west Santiago city Nationality: Filipino

    Civil status: Single

    Religion: Roman Catholic

    Occupation: Office secretary

    Date admitted: 3/4/2011 Time admitted: 8:10am

    Admitting diagnosis: UTI, Pyelonephritis

    Chief complaint: Right lower quadrant and radiatingflank pain since Saturday February 26, 2011.

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    B. HISTORY OF PRESENT ILLNESS

    The day PTA, the patient complained of back painand couldnt stand alone because she felt dizzy andradiating flank pain in night lower quadrant of theabdomen and general also complaining for body

    malaise and painful urination.

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    PAST MEDICAL HISTORY

    The patient has been hospitalized when shewas in 4th yr. high school due to bronchitis

    FAMILY HISTORYThe patient verbalized that her father had also

    suffered urinary tract infection.

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    E. GORDONS FUNCTIONAL PATTERN

    HEALTH PERCEPTION

    BEFORE CONFINEMENT:

    -The patient stated that she consider herself healthybecause she cannot feel something unusual.

    DURING CONFINEMENT:-She stated that shes already unhealthy because she can

    feel pain

    NUTRITION

    BEFORE CONFINEMENT:

    -The patient seldom drink water and sometimes not at all.Shes also fun in eating sweets and salty foods.

    DURING CONFINEMENT:

    -On her first day of confinement the ROD ordered DAT.

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    ELIMINATION PATTERN

    PRIOR CONFINEMENT

    -The patient usually voids for 1-2 times a day. The color ofher urine was dark yellow. However, 1 day PTA shecomplained of pain upon urination in the pain scale 7

    that causes her to void in small quantities. DURING CONFINEMENT

    -She voids 2-4 times a day in normal quantities and slightpain upon urination

    ACTIVITY

    BEFORE CONFINEMENT:-The patient can go to work and stayed at the office from

    7-5 pm can do activity daily living.

    DURING CONFINEMENT:

    -The patient appears weak to go the bathroom.

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    SLEEP/REST PATTERN:

    BEFORE CONFINEMENT:

    -Her usual sleeping pattern was 6-8 hours daily.

    DURING CONFINEMENT:-She is able to sleep 8-10 hours and an hour of snaps

    in the afternoon

    COGNITIVE PERCEPTUAL PATTERN

    -The patient can read and write and her sensesfunctions well. The decision for the benefit of thepatient always comes from her. However, at timesshe asks for assistance her family.

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    SEXUAL PATTERN:

    -The client is single

    COPING STRESS TOLERANCE

    -She asks for assistance from her mother in terms of

    making decision to avoid stress. She managed herproblem through praying.

    VALUES AND BELIEF PATTERNS

    BEFORE CONFINEMENT:

    -She said she attends Sunday masses regularly but herrecent confinement hinders her practice.

    DURING CONFINEMENT:

    -During hospitalization, she prays to GOD to bless her andher family with good health.

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    III.PHYSICAL EXAMINATION

    March 4, 2011

    General appearance:

    The patient looks weak and irritable, complainingpain at the right lower quadrant and radiating flank

    pain, (+) guarding and facial grimace and palelooking with excessive sweating.

    Vital Sign:

    BP: 100/70 mmHg

    Temperature: 38.3 RR: 25 cpm

    PR: 89 bpm

    Parts Technique Abnormal Analysis

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    Parts Technique Abnormal Analysis

    Hair

    Head

    Face

    Eyes

    Ears

    Mouth

    Neck

    Lungs

    Abdomen

    Extremities

    Upper: Nail

    Skin

    Lower: Nail

    Skin

    Inspection

    Inspection

    Inspection

    Palpation

    Inspection

    Inspection

    Palpation

    Inspection

    Inspection

    Palpation

    Inspection

    Palpation

    Percussion

    AuscultationInspection

    Palpation

    Percussion

    Auscultation

    Inspection

    Inspection

    Palpation

    Inspection

    Palpation

    Inspection

    Palpation

    Inspection

    Palpation

    Weak looking and facial

    grimace

    pale, and with eye bags

    Dry mouth, pale, cracked and

    dry lips.

    Shivers

    Pale

    Dry

    Pale

    Pale

    As body response to pain

    Due to inadequate sleep

    As body response to fever and

    fluid loss of the body

    Due to fever

    Response of the body to

    Inflammation

    Due to fever

    Response of the body to

    inflammation

    Due to fever

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    MARCH 5, 2011

    General appearance: the patient looks pale andweak.

    Vital sign: BP: 100/80mmHg

    Temperature: 37.5

    RR: 19 cpm

    PR: 87 bpm

    Parts Technique Abnormal Analysis

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    q y

    Hair

    Head

    Face

    Eyes

    Ears

    Mouth

    Neck

    Lungs

    Abdomen

    ExtremitiesUpper: Nail

    Skin

    Lower: Nail

    Skin

    Inspection

    Inspection

    Palpation

    Inspection

    Palpation

    Inspection

    Inspection

    Palpation

    Inspection

    Inspection

    Palpation

    Inspection

    Palpation

    Percussion

    Auscultation

    Inspection

    Palpation

    Percussion

    Auscultation

    InspectionInspection

    Palpation

    Inspection

    Palpation

    Inspection

    Palpation

    Inspection

    Palpation

    Weak looking

    Pale and with eye bags

    Cracked and dry lips

    Pale

    Dry

    Pale

    Dry

    Due to uncomfortable feeling

    Due to inflammation andinadequate sleep

    Due to fever and fluid loss of

    the body

    Response of the body toinflammation

    Response of the body to

    inflammation

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    IV.LABORATORY RESULTS

    URANALYSIS NORMAL VALUES RESULTS ANALYSIS

    COLOR Amber Dark yellow Urine becomes over

    concentrated with waste that

    makes urine dark yellow

    TRANSPARENCY Clear Turbid The presence of bacteria,

    increase WBC and RBC that

    cause her urine turns to turbid

    SPECIFIC GRAVITY 1.010 - 1.025 1.015

    PH 4.5 8.0 Alkaline

    PROTEIN 6 8 g/d (+) 2 Due to infection, medications,

    and physical stress

    SUGAR 65 99 mg/dl (-)

    A. MARCH 4, 2011

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    URANALYSIS NORMAL VALUES RESULTS ANALYSIS

    WBC 5000 10000/mm3 TNTC Due to her body response to

    invasion, they provide

    components of coagulation,

    transportation and complement

    production during acute

    infection.

    RBC 4.2 5.4 mil/mm3 12 15

    AMORPHUS URATES Moderate

    EPITHELIAL CELLS Moderate

    BACTERIA Many Due to infection

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    HEMATOLOGIC REPORT

    Complete Blood Count Normal Values Results

    Hemoglobin 110 160 g/d 139

    Hemotocrit 34-47 41.5

    White Cell Count 5-10x10 9 23.6

    Segmenters 50-65% 93

    Lymphocytes 25-35% 4.2

    Eosinophils 1-3%

    2.8

    Monocytes 3-7%

    Platelet count 150-450 X 10 9 24

    A. MARCH 4, 2011

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    V.REVIEW SYSTEM

    -ANATOMY OF URINARY SYSTEM

    The urinary system consist of two kidneys, twoureters, the urinary bladder, and the urethra. A largevolume of blood flows through the kidneys, which

    removes substances from the blood to form urine.The urine contains excess water and ion metabolicwastes such as urine and toxic substancesconsumed with food. The urine produce by the

    kidneys flows through the ureters to the urinarybladder, where it is stored until it is eliminatedthrough the urethra.

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    FUNCTIONS OF THE URINARY SYSTEM

    KIDNEYS:

    The major functions of the urinary system areperformed by the kidneys, and the kidneys play thefollowing essential roles in controlling the

    composition and volume of body fluids.

    1. Excretion. The kidneys are the major excretoryorgans of the body. They remove waste products,many of with are toxic from the blood.

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    The kidneys control blood volume by regulating thevolume of urine produced.

    3. The kidneys help regulate the concentration ofmajor ions in the body fluid.

    4. The kidneys help regulate the pH of the fluids.

    5. The kidneys regulate the concentration of redblood cell in the blood.

    6. The kidneys participate with the skin, and liver,invitamin D synthyesis.

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    URINARY BLADDER is a hollow muscularcontainer that lies in the pelvic cavity just posteriorto the pubic symphisis. It functions to store urine,and its size depends on the quality of urine present.

    URETHRA is a tube that exist the urinary bladderinfection and anteriorly the triangle-shape portion ofthe urinary bladder located between the opening ofthe ureters and the opening of the urethra is called

    the trigone. The urethra carries urine from theurinary bladder to the outside of the body.

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    KIDNEY are been shape organs, each about thesize of a tightly clenched fist. They lie in theposterior abdominal wall, behind the peritoneum,with one kidney on either side of the vertebral

    column.

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    OUTER KIDNEY

    Hilium (opening)-where the renal artery and nervesenter and where the renal vein and ureter exit thekidney.

    Renal artery-branch off the abdominal aorta and

    abdominal aorta and enter the kidneys. They giverise to several branches.

    Renal vein-are veins that drain the kidney. Theycorrect the kidney to the inferior vena cava.

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    Renal pelvis-is the funnel-like dilated proximal partof the ureter in the kidney. In humans, the renalpelvis is the point of convergence of two or threemajor calyces.

    URETER-are muscular tubes that proper urine fromthe kidneys to the urinary bladder.

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    INNER KIDNEY

    Cortex-is the outer part of the substance or thekidney, composed mainly of glomeruli andconvulated tubules.

    Renal pyramid -the conical masses composing the

    medullary substance of the kidney.

    Major calyces -in the kidney, surrounds the apex ofthe malphighian pyramids. Urine formed in thekidney passes through a papilla at the apex into a

    minor calyx then into the major calyx beforepassing through the renal pelvis into the ureter. Afusion of minor calyx.

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    Renal artery-brach off the abdominal aorta andenter the kidneys.

    Minor calyces -the cup-shape dilation of theintrarenal ureter, into which a single papilla of a

    multiple-lobe kidney protrudes.

    Nephron -is the basic structure and functional unitof the kidney. Its chief function is to regulate theconcentration of water and soluble substance like

    sodium salts by filtering the blood, reabsorbed whatis needed and excreting the rest of urine.

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    NORMAL KIDNEYS AND PARTS

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    PYELONEPHRITIS

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    URINE FLOW Urine is produced by the processes of filtration, reabsorption

    and secretion.

    FILTRATION

    The renal filtrate passes from the glomerulus into Bowmans

    capsule and contains no blood cells and few blood proteinsthen filtration pressure is responsible for filtrate formation.

    REABSORPTION

    About 99% of the filtrate volume is reabsorbed, 1% becomesurine. Proteins, amino acids, glucose, fructose, sodium,potassium, calcium are among the substances reabsorbed.

    About 65%of the filtrate volume is reabsorbed in the proximaltubule and collecting ducts.

    SECRETIONS

    Hydrogen ions same by-products of metabolism, and somedrugs are actively secreted into the nephron.

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    B. PATHOPHYSIOLOGY

    PYELONEPHRITIS

    Precipitatingfactor:

    Immunocompromise patientLifestyleMisconceptionwith regard toproper hygiene

    care

    Etiology:

    Attachment ofEschericha colibacteria in the

    urethra

    Predisposing

    factor:AgeGenderHealthproblem

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    B. PATHOPHYSIOLOGY

    Proliferation of bacteria in the urethra

    Urethritis

    Urethrovesical reflux

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    B. PATHOPHYSIOLOGY

    Introduction of bacteria to the Ureter

    Inflammation of the Ureter

    Ureteritis

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    B. PATHOPHYSIOLOGY

    Infection ascends to the kidneys

    Pyelonephritis

    Activation of theimmune response

    GeneralBody

    Malaise

    Nauseaandvomiting

    Dysuria

    Colic

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    B. PATHOPHYSIOLOGY

    Release ofpyrogens from

    bacteria

    Release ofprostaglandins E2

    Elevation of thebody thermostat bythe hypothalamus

    Flankpain

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    B. PATHOPHYSIOLOGY

    Vasoconstriction

    Shivers

    Fever

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    VII. NURSING CARE PLAN

    March 4, 2011

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    ASSESSMENT DIAGNOSIS PLANNING INTERVENTION RATIONALE EVALUATION

    SUBJECTIVE:

    Giniginaw ako

    as verbalized by

    the patient.

    OBJECTIVE:

    -Warm to touch

    flush face teary

    eyes shivering

    -TEMP: 38.3c

    -chills

    Alteration in

    thermoregulator:

    hyperthermia r/t

    bodys response

    against invading

    pyrogens 2 to

    UTI.

    After 30 minutes

    of continuous

    nursing

    intervention the

    patient will be

    able to stabilized

    body

    temperature in

    normal

    range.from 38.3-

    37.5 c

    Monitor v/s

    Wrap in warm

    blankets extra

    clothing and

    check clothing.

    Provide warm

    liquids if the

    client can

    swallow

    Close the

    window and

    doors and turns

    the light on.

    Turn off electric

    fan and aircon if

    necessary

    Provide extra

    pillow beside thepatient

    Administer

    paracetamol as

    prescribed by the

    ROD

    -For base line

    data

    -To provide warm

    and comfort.

    -To elevate the

    body

    temperature

    After 30 minutes

    of continuous

    nursing

    intervention the

    patient was able

    to stabilized body

    temperature

    from 38.3 to 37.2

    c

    -GOAL MET-

    March 4, 2011

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    ASSESSMENT DIAGNOSIS PLANNING INTERVENTION RATIONALE EVALUATION

    SUBJECTIVE:

    Masakit tang

    tagiliran ko

    hanggang likod ko.

    As verbalized by thepatient.

    OBJECTIVE:

    Facial grimace

    guarding irritable

    body weakness pale

    -Pain scale:8/10

    Acute pain r/t an

    inflammatory

    process in the

    kidney.

    After 30 minutes or

    1 hour of giving

    appropriate

    intervention, the

    patient will be ableto alleviate pain.

    Monitor v/s and

    record

    Perform a

    comprehensive

    assessment of painseverity(0-10 scale)

    Encourage

    verbalization of

    feelings about pain

    Provide quit

    environment

    comfort measures

    like back rubEncourage

    adequate rest period

    Keep comfortable.

    -For baseline data

    -For baseline data

    -Help determine

    possibility of

    underlying condition-To prevent fatigue

    -To provide non

    pharmacologic pain

    management

    -To prevent fatigue

    -For quick recovery

    After 30 minutes or

    1 hour of giving

    appropriate

    intervention, the

    patient was able toelevate pain.

    -GOAL MET-

    March 4, 2011

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    ASSESSMENT DIAGNOSIS PLANNING INTERVENTION RATIONALE EVALUATION

    SUBJECTIVE:

    Nagsusuka akoas

    verbalized by the

    patient.

    OBJECTIVE:-Pale

    -weak looking

    -dry skin and lips

    -restlessness

    (+)vomit for 3 times

    Risk for deficient

    fluid volume r/t

    nausea and

    vomiting secondary

    to dehydration.

    After 30 minutes to

    1 hour the patient

    will be able to

    maintain fluid

    balance.

    Monitor v/s

    Monitor I and O

    balance, being

    aware of altered

    intake outputEncourage the

    client to increase

    fluid intake at least

    6-8 glasses a day.

    Review

    appropriate use of

    medication

    Give hard candies

    -For baseline data

    -To ensure accurate

    picture of fluid

    status

    -To maintain fluidand electrolytes

    balance

    - To have potential

    for causing of

    exacerbating

    Dehydration.

    -To lessen the

    stimulation of saliva

    that enduses

    vomiting

    After 30 minutes to

    1 hour the patient

    was able to

    maintain fluid

    balance.-GOAL MET-

    March 4, 2011

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    ASESSMENT DIAGNOSIS PLANNING INTERVENTION RATIONALE EVALUATION

    OBJECTIVE:

    -Small frequent

    urination with pain-PAIN SCALE:7/10

    -WBC:

    TNTC

    -DYSURIA

    -Urine analysis:

    -COLOR: Dark

    yellow

    TRANSPARENCY:Tur

    bid

    -S.G.:1.015

    -PH: Alkaline

    -PROTINE: +2

    SUGAR: -

    RBC:12-15

    Impaired urinary

    elimination r/t

    inflammation of

    bladder mucosa

    Within 8 hours of

    nursing intervention

    the patient

    verbalizeunderstanding of

    condition and

    techniques to

    prevent urinary

    tract infection (UTI)

    Monitor v/s

    Encourage fluid

    intake at least 8-10

    glasses a dayDiscuss possible

    dietary restriction

    base on individual

    symptoms.

    Discuss proper

    genitalia cleansing

    and using of

    feminine wash

    Monitor and

    assess urine output

    -For baseline data

    -To help maintain

    renal function,

    prevent infectionand urinary stones

    -To help elevate the

    present condition

    -To let the patient

    understand the said

    topics

    -For base line data,

    for any particular

    changes

    Within 8 hours of

    nursing intervention

    the patient

    verbalizedunderstanding of

    condition and

    techniques to

    prevent urinary

    tract infection (UTI).

    -GOAL MET-

    March 5, 2011

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    ASESSMENT DIAGNOSIS PLANNING INTERVENTION RATIONALE EVALUATION

    SUBJECTIVE:

    Nanghihina ako as

    verbalized by the

    patientOBJECTIVE:

    -Decrease range of

    motion

    -weak looking

    -pale

    -irritable

    -slowed movement

    Impaired physical

    mobility r/t

    decrease muscle

    strength secondaryto fatigue

    After 2-3 hours of

    nursing intervention

    the patient will able

    to increase strengthand function of

    compensatory body

    parts.

    Establish rapport

    Assess nutritional

    status and clients

    report of energywith monitor v/s

    Provide comfort

    measures such as

    therapeutic touch

    Encourage the

    patient to eat

    nutritious food

    which is rich in

    vitamin c such as

    orange fruits,

    malunggay.

    Identify energy

    conserving

    techniques for ADLs

    Schedule activitieswith adequate rest

    periods during the

    day.

    Provide safety

    measures

    -To gain trust and

    cooperation

    -For baseline data

    -To provide comfort-To promote well

    being and maximize

    energy production

    -To limits fatigue,

    Maximize

    participation.

    -To relive fatigue

    -To prevent falling

    After 2-3 hours of

    nursing intervention

    the patient was able

    to increase strengthand function of

    compensatory body

    parts.

    -GOAL MET-

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    VIII. DRUG STUDY

    DRUG(CLASSIFICATON)

    INDICATION ACTION ADVERSE EFFECT CONTRAINDICATION NSG. CONSIDERATION

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    CEFUROXIME

    Brand name : Ceftin

    (Anti-infectives)

    750mg IV

    For Urinary tract

    infection

    Second-generation

    cephalosporin that

    inhibits cell-wall

    synthesis promoting

    osmotic instability;usually bactericidal.

    CV: Phlebitis

    GI: nausea, vomiting,

    diarrhea

    Other:

    hypersensitivityreaction

    Contraindicated in

    patients

    hypersensitive to

    drug and other

    Cephalosporins. Usecautiously in the

    patients

    hypersensitivity to

    penicillin because of

    possibility of cross-

    sensitivity with other

    beta-lactam

    antibiotics.

    Before giving

    ask patient if

    she has

    allergies to

    penicillins orcephalosporin.

    Obtain

    sensitivity test

    before giving

    the first dose.

    If large doses

    are given,

    therapy is

    prolonged or

    patient is at

    risk, monitor

    patient for sign

    and symptoms

    of infection.

    Look-alike-sound alike:

    Dont confuse

    drug with other

    Cephalosporins

    that alike

    DRUG(CLASSIFICATON)

    INDICATION ACTION ADVERSE EFFECT CONTRAINDICATION

    NSG. CONSIDERATION

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    GENTAMICIN

    (Anti-infectives)

    80mg IV

    Serious

    infections

    caused by

    sensitive strains

    of

    pseudomonas

    aeruginosa,

    Escherichia coli,

    Proteus,

    Klebsiella or

    Staphylococcus

    Inhibits protein

    synthesis by

    binding directly

    to the 30s

    ribosomal

    subunits;

    bactericidal.

    CNS: fever,

    headache,,

    lethargy,confusion,

    dizziness

    CV:Hypotension

    Respiratory: Apnea

    GI: vomiting, nausea

    Skin: rash

    Contraindicated in

    patients

    hypersensitivity to

    drug or other

    aminoglycosides.

    Use cautiously in

    neonates, infants,

    elder patients with

    impaired renal

    function or

    neuromuscular

    disorders.

    Obtain sensitivity tests before

    giving first dose.

    Evaluate patients hearing

    before and during therapy.

    Notify and during therapy.

    Notify prescriber if patients

    complain tinnitus, vertigo,

    hearing loss.

    Weight patient and review

    renal function studies before

    therapy begins.

    Obtain blood peak gentamicin

    level 30 minutes after IV

    infusion finishes.

    Monitor renal function

    Watch for s/sx of

    superinfection

    Therapy usually continues for

    7-10days. If no response occurs

    in 3-5days, stop therapy and

    obtain new specimen forculture and sensitivity.

    DRUG

    (CLASSIFICATON)

    INDICATION ACTION ADVERSE EFFECT CONTRAINDICATI

    ON

    NSG.

    CONSIDERATION

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    (CLASSIFICATON) ON CONSIDERATION

    METOCLOPRAMID

    E

    (antiemetics)

    1amp IV

    To prevent or

    reduce nausea

    and vomiting

    Stimulates

    motility of

    upper GI tract,

    in cases lower

    esophageal

    sphincter tone,

    and blocks

    dopamine

    receptors at

    the

    chemoreceptortrigger zone.

    CNS: fatigue,

    anxiety

    CV: Hypotension

    GI: nausea, bowel

    disorders,

    diarrhea

    GU: urinary

    frequency,

    incontinence

    Skin: rash

    Contraindicated

    in patients

    hypersensitivity

    to drug.

    Contraindicated

    in patients for

    whom

    stimulation of GI

    motility might be

    dangerous (those

    withhemorrhage,

    obstruction or

    perforation)

    Monitor bowel

    sounds.

    Safety and

    effectiveness of

    drug havent

    been established

    for therapy

    lasting longer

    than 12 weeks.

    Alert: use 25mg

    diphenhydramine IV counteract

    extrapyramidal

    adverse effects

    from high doses.

    DRUG(CLASSIFICATON)

    INDICATION ACTION ADVERSE EFFECT CONTRAINDICATION

    NSG. CONSIDERATION

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    KETOROLAC

    Brand name: Toradol

    (non steroidal anti-

    inflammatory drugs)

    1amp IV

    Short-term

    management of

    moderately

    severe, acute

    pain for single

    dose treatment.

    May inhibit

    prostaglandin

    synthesis, to

    produce anti-

    inflammatory,

    analgesic and anti-pyretics.

    CNS: dizziness,

    headache

    GI: vomitin,

    flatulence

    Skin: rash

    Other: pain atinjection site.

    Contraindicated in

    patients

    hypersensitivity to

    drug and in those

    with advanced renal

    impairment andthose at risk for

    renal impairment

    depletion or at risk

    of bleeding.

    Contraindicated as

    prophylactic

    analgesic before

    major surgery or

    intraoperatively

    when hemostatic is

    critical; and in

    patients currently

    receiving aspirin, an

    NSAID or pronecid.

    Alert. The maximum

    combined duration

    of parenteral and

    oral therapy is 5

    days.

    Dont give drugsepidurally or

    intrathecally because

    of alcohol content.

    NSAIDs may mask

    the s/sx of infection

    because of their

    antipyretic and

    inflammatory

    actions.

    Serious GI toxicity,

    including peptic

    ulcers and bleeding,

    can occur in patient

    taking NSAIDs,

    despite lack ofsymptoms.

    Look-alike-sound

    alike: dont confuse

    Toradol with Tegretol

    or Foradil

    DRUG(CLASSIFICATON)

    INDICATION ACTION ADVERSE EFFECT CONTRAINDICATION NSG.CONSIDERATION

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    Calcium Carbonate

    Brand name:

    Contylan

    (antacid and

    antiflatulent)

    Used for acute

    hypocalcemiaa,

    electrolyte

    depletion,

    cardiac arrest,

    hyperkalemiaand

    hypermagnesia.

    Used in chronic

    hypocalcemia,

    calcium

    deficiency, and

    as an antacid.

    Used treatment

    of

    hyperphosphat

    emia

    Calcium is essential

    for function, integrity

    of nervous, muscular

    and skeletal systems.

    It plays an important

    role in normal cardiacand renal function,

    respiration blood

    coagulation, cell

    membrane and

    capillary

    permeability. It

    assists in regulating

    the release and

    storage of

    neurotransmitters

    and hormones.

    Calcium neutralizes

    or reduces gastric

    acid production.

    CNS: headache

    CV: Hypotension

    GI: nausea, vomiting

    GU: difficult or

    painful urination

    Skin: flushing,warmth, rash,

    redness, sweating

    Other: burning

    sensation at injection

    site

    No contraindicated

    had notify.

    Assess bp, ECG

    reading, renal

    function.

    Give syrup

    diluted in juice

    or water. Chew chewable

    tablet well

    before

    swallowing.

    Monitor for sign

    of

    hypercalcemia.

    DRUG INDICATION ACTION ADVERSE EFFECT CONTRAINDICATIO NSG. CONSIDERATION

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    N

    PARACETAMOL

    Classification:

    -Therapeutics:

    Antipyretics, non

    opioid analgesics

    Mild pain and

    fever

    Inhibits to synthesis

    of prostaglandins

    that serve as

    medicines of pairs

    and fever primarily

    in the CNS has no

    significant anti-

    inflammatory

    properties or G.I

    toxicity

    GI: hepatic failure,

    hepatoxicity

    GV: Renal failure(high

    doses/chronic use)

    HEMAT: neutropehia.

    Fancy topenia,

    Leukopenia

    DERM: rash, urticaria

    Previous

    hypersensitivity

    products

    containing alcohol,

    aspartame,

    sacharin, sugar or

    tartrazine should

    be avoided in

    patients who have

    hypersensitivity or

    intolerance to

    these compound.

    Assess overall

    health status and

    alcohol usage

    before

    administering

    paracetamol

    patients who are

    malnourished or

    chronically abuse

    alcohol are at

    higher risks of

    developing

    hepatotoxicity With chronic use

    of usual doses of

    drugs.

    Assess amount

    frequently and

    type of drugs taken

    in patients self

    medicating,

    especially with

    over the counter

    drugs prolonged

    use of paracetamol

    increase the risk of

    adverse renal

    effects.

    Assess fever: Note

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    END OF CASE

    PRESENTATIONTHANK YOU!

    GROUP 1 (GROUP BULILIT & BAGTIT!)