PROGRAM - event-consulting.roevent-consulting.ro/uploads/files/Program(2).pdfZvezdana Kojic . The 30th Conference of Physiology: ”Integrative physiology – From fundamental mechanisms

The 30th Conference of Physiology:

”Integrative physiology – From fundamental mechanisms to biomedical application”

27th to 29th of September 2018

Cluj-Napoca, Grand Hotel Napoca

The 30th Conference of Physiology

”Integrative physiology – From fundamental

mechanisms to biomedical application”

PROGRAM

27th – 29th of september 2018

Cluj-Napoca





Committees

President of the Conference: Prof. Dr. Simona Clichici

President of honor: Prof. Dr. Adriana Mureşan

Scientific committee Prof. Dr. Anca Bădărău (Bucureşti)

Conf. Dr. Adrian Tudor Bălșeanu (Craiova)

Conf. Dr. Florina Bojin (Timişoara)

Prof. Dr. Anca Dana Buzoianu (Cluj-Napoca)

Conf. Univ. Dr. Cătălina-Mariana Ciornei (Bucureşti)

Conf. Dr. Petrişor Cismaş-Pruteanu (Oradea)

Prof. Dr. Simona Clichici (Cluj-Napoca)

Prof. Dr. Dan Dobreanu (Târgu-Mureş)

Prof. Dr. Adriana Filip (Cluj-Napoca)

Conf. Dr. Maria Grama (Sibiu)

Conf. Dr. Adriana Habor (Târgu-Mureş)

Prof. Dr. Ileana Ion (Constanţa)

Conf. Dr. Károly Orbán-Kis (Târgu-Mureş)

Conf. Dr. Dana Motoc (Arad)

Prof. Dr. Adriana Mureşan (Cluj-Napoca)

Conf. Dr. Simona Mureşan (Târgu-Mureş)

Prof. Dr. Remus Orăsan (Cluj-Napoca)

Prof. Dr. Carmen Panaitescu (Timişoara)

Conf. Univ. Dr. Ioana-Raluca Papacocea (Bucureşti)

Prof. Dr. Virgil Păunescu (Timişoara)

Conf. Dr. Manuela Pumnea (Sibiu)

Prof. Dr. Alina Scridon (Târgu-Mureş)

Prof. Dr. Veronica Sfredel (Craiova)

Prof.Dr. Şoimiţa Suciu (Cluj-Napoca)

Prof. Dr. Tibor Szilagyi (Târgu-Mureş)

Prof. Dr. Lăcrămioara Șerban (Iaşi)

Prof. Dr. Dragomir Șerban (Iaşi)

Conf. Dr. Carmen Tatu (Timişoara)

Prof. Dr. Gabriela Tănăsie (Timişoara)

Conf. Dr. Adelina Vlad (Bucureşti)

Conf. Dr. Dana Zaha (Oradea)

Prof. Dr. Leon Zăgrean (Bucureşti)

Conf .Dr. Ana Maria Zăgrean (Bucureşti)





International Scientific Committee János Almássy (Debrecen)

Mehmet Akif Baktir (Erciyes)

Nina Belova (Sofia)

Dragan Djuric (Belgrade)

Vladimir Jakovljevic (Kragujevac)

Rita Kiss (Debrecen)

Zvezdana Kojic (Belgrade)

Olga Pechanova (Bratislava)

Sinisa Ristic (Sarajevo)

Leila Tekaya (Tunis)

Organising committee: Prof. Dr. Simona Clichici

Prof. Dr. Adriana Filip

Prof. Dr. Şoimiţa Suciu

Ş.L. Dr. Ramona Simedrea

Ş. L. Dr. Irina Chiş

Ş.L. Dr. Daniela Mitrea

Ş. L. Dr. Lavinia Sabău

Ş.L. Dr. Cezar Login

Ş.L. Dr. Ioana Bâldea

Ş.L. Dr. Teodora Mocan

Ş.L. Dr. Hana Decean

Asist. Dr. Cristina Bidian

Asist. Dr. Oana Hoteiuc

Asist. Dr. Alina Toader

Asist. Dr. Alexandra Berghian-Sevastre

Asist. Dr. Cristina Olănescu

Asist. Drd. Alexandra Pop

Asist. Drd. Nadina Pop

Drd. Diana Tudor

Drd. Victoria Ruţă

Drd. Teodora Timiş

Drd. Mihai Lupu

Drd. Tudor Dimitriu

Secretary:

Bianca-Dumitrița Barabas-Bunea





SCIENTIFIC PROGRAM

Thursday, 27th of september 2018 Conference sessions

08.00 – 18.00 Registration

FORUM ROOM

09.00 – 12.00 Oxidative stress evaluation – from basic mechanisms to assessment of

the biocompatibility and efficacy of some modern therapies

Coordinators:Simona Clichici, Adriana Filip, Şoimiţa Suciu

Oxidative stress and antioxydants

Şoimiţa Suciu In vitro methods of testing biocompatibility of new drugs, or medical

devices containing natural compounds

Ioana Bâldea The relationship of oxidative stress with inflammatory mediators

Adriana Filip The oxidative stress in extreme conditions

Daniela Mitrea Perspectives on Oxidative Stress in Relation to Carbon Nanotubes

Teodora Mocan Effects of the naturals and synthesis antioxidants in diabetic

neuropathy

Irina Chiş Oxidative stress and air pollutants

Cristina Bidian Interactions between antioxydants and cytostatic drugs

Diana Olteanu

15.30 – 17.40 Workshop: Modern trends in experimental research - ethical and legal

issues

Chairmen: Coman Cristin, Marcus Ioan, Sevastre Bogdan, Sevastre-

Berghian Alexandra, Maria Aluaş

Legislation on animal experimentation in Romania

Cristin Coman





Ethics of Animal Experimentation

Ioan Marcus

Stem cells research and therapy – ethical and legal issues

Maria Aluaş

Reporting of severity in animal experimentation projects –a practical

approach

Bogdan Sevastre

12.00 – 15.30 Registration

12.00 – 14.00 At the Physiology Discipline, Clinicilor street no. 1

Workshop (hands-on): Stem cells in regenerative medicine

Trainers: Ioana Bâldea, Remus Moldovan

12.00 – 17.00 At the Physiology Discipline, Clinicilor street no. 1-3

Workshop (hands-on) : Modern Trends in Testing of Digestive

Transit of Natural and Synthetic Materials

Trainers: Teodora Mocan, Simona Clichici

12.00 – 14.00 At the Center of Practical Skills and Simulation in Medicine,

Marinescu street, no. 23.

Workshop (hands-on) : Ultrasonophysiology – using ultrasonography

as a technique for the study of the Physiology

Trainers: Oana Hoteiuc, Claudiu Bădulescu, Irina Chiş

17.40 – 18.00 Coffee break

18.00 – 18.30 OPENING CEREMONY

Prof. Dr. Simona Clichici - President of the Conference

Prof. Dr. Anca Buzoianu - Dean of the Faculty of Medicine, Cluj-Napoca

Prof. Dr. Carmen Panaitescu - President of the Romanian Society of

Physiology

Prof. Dr. Adriana Mureșan – Honorary President of the Conference

Prof. Dr. Dragan Djuric - President, Assembly, Serbian Physiological

Society

Prof. Dr. Nina Belova – on behalf of the Bulgarian Society of Physiology

Prof. Dr. Janos Almassy - on behalf of the Hungarian Society of

Physiology





18.30 – 19.15 New perspectives on mechanisms of communication in biological systems

Leon Zăgrean

19.30 – 21.00 Welcome Reception

Friday, 28th of september 2018

08.30 – 09.00

Forum room

09.00 – 10.30

09.00 – 09.20

09.20 – 09.40

09.40 – 10.00

10.00 – 10.15

10.15 – 10.30

General Assembly of The Romanian Society of Physiology (SRF)

SESSION 1: Basic mechanisms with clinical impact

Chairmen: Dragan Djuric, Simona Clichici, Carmen Panaitescu

Acute And Subchronic Methionine Overload Induce Different

Cardiovascular Effects In Rats: Non-Homocysteine Dependent

Mechanisms

Dragan Djuric

The Role Of Stem Cells In Regenerative Medicine

Virgil Păunescu

Arterial Stiffness And Haemodynamics

Nina Belova

How does dantrolene inhibit the ryanodine receptor?

Janos Almassy

Effects Of Polyphenolic Compound And Statin Therapy In

Experimental Metabolic Syndrome

Olga Pechanova


11.00 – 12.00

11.00 – 11.25

11.25 – 11.50

11.50 – 12.00

SESSION 2: Back to Physiology: Reverting the Allergic Response

Chairmen: Virgil Păunescu, Carmen Panaitescu

Ragweed pollen allergy – patterns of sensitization

Carmen Panaitescu

Recombinant allergens for improving Ambrosia allergy diagnosis

and therapy

Kuan Wei Chen

Recombinant Amb a 8, a candidate for the improvement of

ragweed allergy diagnosis and therapy

Maria Roxana Buzan





12.00 – 13.00 Early life stress and health: a physiological perspective

Andrei Miu

11.00 – 13.00 Ambasador room

11.00 – 11.15

11.15 – 11.30

11.30 – 11.45

11.45 – 12.00

12.00 – 12.15

12.15 – 12.30

12.30 – 12.45

12.45 – 13.00

SESSION 3: Advances in cardiac and vascular physiology – from

mechanism to clinical application

Chairmen: Danina Muntean, Alina Scridon, Ionela Serban

Monoamine oxidases are sources of vascular oxidative stress in

the setting of inflammation in patients undergoing elective

abdominal surgery

Adrian Sturza

Interrelations between pulse wave speed and ECG – A possible

cuffless measurement method for systolic blood pressure?

Marcel Perian

An experimental model for Angiotensin II-induced arterial

hypertension

Minela Maranduca

The impact of chronic ivabradine administration on

transesophageal pacing-induced atrial fibrillation

Alkora Balan

Effects of chronic ivabradine administration on ventricular

arrhythmogenesis in in vivo rats

Maria Flavia Rădulescu

Chronic ivabradine administration prevents exaggerated heart

rate lowering during acute in vivo parasympathetic stimulation

Vasile Bogdan Halațiu

Bisphenol A – effects on hemodynamic and autonomic

parameters and on cardiac arrhythmogenesis in healthy female

rats

Saleh Samer

Isoproterenol induced myocardial infarction in rats: dose

identification

Paul Boarescu

13.00 – 14.00 Pause/Lunch

14.00 – 15.00 Ambasador Room

Educational session supported by the company AstraZeneca

Ioana Agache, Carmen Panaitescu, Laura Marusciac





14.00 – 15.00

Forum room

14.00 – 14.20

14.20 – 14.40

14.40 – 15.00

SESSION 4: From intracellular signalling pathways to clinical

relevance

Chairmen: Şoimiţa Suciu, Remus Orăsan

New insights in receptors signalling

Anca Buzoianu

Crosstalk between monoamine oxidase and vitamin D: new

roles for old friends

Danina Muntean

Is Psoriasis Vulgaris a Skin Disease or a Multisystem

Generalized Disease?

Remus Orăsan

15.00 – 15.30 POSTER SESSION (Posters 1 – 10)

Chairmen: Adrian Bălșeanu, Carmen Tatu, Ioana Bâldea

15.30 – 17.00

Forum Room

15.30 – 15.45

15.45 – 16.00

16.00 – 16.10

16.10 – 16.20

16.20 – 16.30

16.30 – 16.40

16.40 – 16.50

SESSION 5: Neurocognitive and behaviour functions –

physiological mechanisms and pathological impact

Chairmen: Sinisa Ristic, Veronica Sfredel, Adriana Filip

Functional neuroimaging a review of the preclinical and

clinical state of the art

Sinisa Ristic

Optical properties of blood in a group of subjects with ischemic

stroke

Veronica Sfredel

Old roads with new connections: landmarks in diagnosis and

pathophysiological mechanisms in rare diseases, focus on

treatable neuro-metabolic disorders

Romana Vulturar

Aquaporin 4 and the central nervous system glia scaring

Cătălin Bogdan

Chloride transportation modulation impacts on neuronal

viability in mature hippocampal cultures exposed to oxygen-

glucose deprivation and reoxygenation

Diana Maria Chitimus

Maternal high-fat diet influences the immature rat

hippocampus exposed to perinatal asphyxia

Mara Ieșanu

Characterization and biological effects of hypericum extracts on

anxiety-like behavior, oxidative stress and inflammation in rats





16.50 – 17.00

Alexandra Berghian

Neuroprotective treatments in experimental hypoxic-ischemic

encephalopathy

Alina Toader

15.30 – 17.00 Ambasador room

15.30 – 15.45

15.45 – 16.00

16.00 – 16.10

16.10 – 16.20

16.20 – 16.30

16.30 – 16.40

16.40 – 16.50

16.50 – 17.00

SESSION 6: New insights in physiological and pathological

mechanisms: from experimental to clinical approach

Chairmen: Janos Almassy, Anca Bojan, Ionela Șerban

The role of melanin concentrating hormone (mch) in the

pathomechanism of childhood obesity and diabetes mellitus

Rita Kiss

Principles of immunotherapy in hematologic malignancies

Anca Bojan

The sphingolipids signalling pathway - new diagnosis tool of

hepatocellular carcinoma

Iuliana Nenu

Influence of sound on the reproductibility – experimental

results on animals

Cristin Coman

Antiproliferative and antioxidant effects of pomace extracts

from fetească neagră and pinot noir cultivars

Alina Pârvu

MPMoIII as criteria for interhospital transportation of

polytrauma patients. Pilot study

Oleg Arnaut

Functional changes of the retina in diabetic patients

Cornelia Tănasie

Thrombophilia screening in pregnancy - is useful or not?

Liliana Hurjui


17.30 – 19.00

Forum Room

17.30 – 17.45

SESSION 7: Advances in oral cavity physiology: materials,

mechanisms and their clinical impact

Chairmen: Zvezdana Kojic, Anca Bădărau, Adriana Filip

Newly-designed alpha tricalcium phosphate cement:

biocompatibility study

Zvezdana Kojic





17.45 – 18.00

18.00 – 18.10

18.10 – 18.20

18.20 – 18.30

18.30 – 18.45

18.45 – 19.00

Tooth physiology – terra incognita

Vasile Zagnat

The organic growth factors role in the oral cavity level

Raluca Jipu

Researches concerning the impact of the salivary secretion

dysfunctions in the oro-maxilo-facial area

Irina Grădinaru

Influence of cardiovascular diseases on salivary parameters

Carina Balcoș

Chemopreventive effects of two antioxidants, the grape seed

extract burgund mare and curcumin, on oral carcinogenesis

Ioana Scrobotă

Co-transplantation of immunostimulatory macrophages and

mesenchymal stem cells for the regeneration of the optic nerve

in an animal model of glaucoma

Olga Sorițău


Educational session supported by the company Worwag

Simona Clichici, Petru A. Mircea

18.30 – 19.15

20.00

POSTER SESSION 2 (Posters 11 – 25)

Chairmen: Raluca Papacocea, Cătălin Bogdan, Marcel Perian

GALA DINNER

Bricks Restaurant

Voucher access

Saturday, 29th of september 2018

09.00 – 09.30

09.30 – 11.00

Forum room

09.30 – 09.40

The Role Of Exercise In Cardiovascular Homeostasis: From Basic

Science To Applied Clinical Investigations

Vladimir Jakovljevic

SESSION 8: Young physiologists symposium

Chairmen: Carmen Tatu, Daniela Mitrea, Cătălin Bogdan

Nanotechnology for Improvement of Human Dental Follicle derived

Stem Cells Differentiation into Retinal Progenitors

Adrian Sorițău





09.40 – 09.50

09.50 – 10.00

10.00 – 10.10

10.10 – 10.20

10.20 – 10.30

10.30 – 10.40

10.40 – 10.50

10.50 – 11.00

Study of PDT antiangiogenic effect in melanoma-endothelial cells co-

cultures

Ioana Teacoe

Curing Ambrosia allergy one step at a time. An insight into Amb a 6

allergen expression

Robert Gal

Effects of acute and subacute hypobaric hypoxia on oxidative stress

biomarkers: a study on the Alps

Luca di Natale

Thymus plant extract improves glucose levels and reduces oxidative

stress in experimental diabetes mellitus

Andrei Mitre

Antioxidative and Antidiabetic Effects of Thiazolidinediones in

Streptozotocin-Induced Diabetes type 1

Dinu Bolunduț

Intervention of Spironolactone in the oxidative and inflammatory

processes in the periovarian adipose tissue of the PCOS-induced rats

Danusia Pușcaș

The detrimental effects of silver nanoparticles functionalizes with

Cornus Mas L. Extract on the rat testicle

Răzvan Opriș

A new approach in the treatment of experimental cholestasis using

silymarin coated nanoparticles

Roxana Cimponeriu


09.30 – 09.45

09.45 – 10.00

10.00 – 10.10

10.10 – 10.25

SESSION 9: Biocompatible natural and synthetic compounds

with biomedical applications

Chairmen: Luminiţa David, Annamaria Pallag, Olga Soritau

Anti-inflammatory activity of some novel phytosynthesized

flavonoid bioconjugated noble metal nanoparticles

Luminita David

Signaling pathways involved in chemoprevention with biomaterials

based on silver nanoparticles in oral dysplastic keratinocytes

Adriana Filip

Effects of equisetum arvense l. extract on endothelial vascular cells

exposed to hyperosmotic stress

Annamaria Pallag

Biodistribution and effects of a capsular hybrid formulation

natural-synthetic

Teodora Mocan





10.25 – 10.40

10.40 – 10.50

10.50 – 11.00

Evaluation of biocompatibility in vivo of two antifungal agents

derived from ketoconazole

Ioana Bâldea

Effects of thiazolidinediones on nerve functions in experimental

diabetic peripheral neuropathy

Irina Chis

The dual role of Metformin as an adjuvant in photodynamic therapy

against melanoma

Diana Tudor

11.00 – 11.40

11.40 – 12.00

POSTER SESSION 3 (26 – 39)

Chairmen : Cătălina Ciornei, Daniela Matei, Irina Chiș

Coffee break

12.00 – 13.00

Sala Forum

12.00 – 12.20

12.20 – 12.40

12.40 – 13.00

SESSION 10: New approches in teaching and research

Chairmen: Carmen Tatu, Ileana Ion, Simona Clichici

Integrity – the integral dimension of excellence in research

Maria Aluaș

An attempt to re-define traditional teaching methods in physiology

Cezar Login

First inter-medical school physiology quiz

Nicu Andronic

13.00 – 14.00

Sala Forum

CONCLUDING REMARKS, AWARDS and

TAKE HOME MESSAGES

Chairmen: Simona Clichici, Carmen Panaitescu





POSTER SESSION

FRIDAY, 15.00 – 15.30

1. Propolis - The Natural Bioregulator In Diabetes And In Improving The Of The Gonadotropic Hormones

Elena Chiriță

2. Modifications Of Corticosteron In The Experimental Diabetes On The Background Of The Propolis

Tincture Administration

Bacalov Iurie

3. Cardiovascular Response In Sleep Deprived Subjects

Papacocea Ioana Raluca

4. Oxidative Stress Is A Key Factor In Patients With Traumatic Brain Injury

Papacocea Ioana Raluca

5. Study Of Circadian Changes Of Hemostase At Birth

Ioana Anca Bădărău

6. Chronic Administration Of [Acei] And [Arbs] May Improve Scopolamine-Induced Memory Impairment In

Mice

Daniela-Carmen Ababei

7. Osteoporosis, inflammation and periodontal disease

Dan Piperea-Sianu

8. Lipid Fractions That Correlate With Insulin Resistance In Newly Diagnosed Type 2 Diabetes Patients

Cosmin Vesa

9. Ecg Changes In Acute Co Poisoning

Mariana Catalina Ciornei

10. The Influence Of Body Mass Index On Retinal Vascular Caliber In Patients With Arterial Hypertension

Alina Gabriela Dumitrescu

FRIDAY, 18.30 – 19.15

11. Therapeutical Potential Of Intravenous Curcumin Administration In Experimantal Migraine

Alexandra Bulboaca

12. Is p-gp a cause of the interaction between amiodarone and furosemide?

Maria Adriana Neag

13. The Importance Of Q-T Interval Changes In Patients With Atrial Fibrillation

Irina-Anca Eremia

14. Cortical Oscillations In An Animal Model Of Dystonia Caused By Cerebellar Dysfunction

Ioana Antoaneta Georgescu

15. The Pathophysiology Of Smooth Utero-Tubular Muscles

Roxana Mihaela Barbu

16. Renal Denervation Impact Upon The Baroreflex Control Of The Heart Rate In The Model Of Reduced

Renal Mass, Salt Sensitive Volume-Overload Hypertension

Şerban Dragomir-Nicolae

17. Cytokines In Bronchoobstructive Airways Diseases

Ioana Corina Bocsan

18. Evaluation Of Serum Transaminases In Hypoxia

Mihai Livia Gratiela

19. Motor Behavior In Mice During Dystonia Induced By Cerebellar Kainic Acid Application

Razvan-Alexandru Steopoaie

20. Effect Of Implanted Nanoparticles Of Polylactic Acid (Npllla) Enriched Bone Cement On A Femoral Experimental Defect In Rats – Preliminary Results

Alexandra Iulia Blidaru





21. Possible Benefits Of Selenium Supplementation In Autoimmune Thyroiditis

Ionela-Lăcrămioara Şerban

22. Topical Application Reinforced By Low-Level Laser Therapy On An Animal Model Of Hair Regrowth - New Zealand Rabbits

Meda Sandra Orasan

23. Success of cardiac resynchronization in a patient with ischemic cardiomyopathy. A case report

Irina Mușa

24. Interventional therapy in mitral regurgitation as an alternative to surgical treatment? A case report.

Andrei Meșină

25. Early Markers For Cardiovascular Damage In Patients With Pulmonary Silicosis Before The Occurrence

Of Chronic Pulmonary Heart

Georgică Târtea

Saturday, 11.00 – 11.40

26. The Effect Of Three Different Doses Of Rhodiola Rosea, On Intense Physical-Stress

Ramona-Niculina Jurcău

27. Effect Of Schisandra Chinensis On Heart Rate, Glycemia And Malondialdehyde, In Exercise-Stress


28. Influence Of Astragalus Versus Placebo, On Anxiety And Glycemia In Psychological-Mental Stress


29. Exploration Scintigraphy In Parathyroid Pathology

Carmen Angela Sfrangeu

30. When Nature Does Not Help Physiology – The Use Of Recombinant Allergens For The Study Of The

Allergic Immune Response

Laura Marusciac

31. Experimental Orthodontic Bracket Bonding Material Testing

Anca Mesaros

32. In Silico Insight Into Epigenetic And Transcription Chemopreventive Signaling Mechanism In Oral Cancer

Ramona Suharoschi

33. Clinical And Hematological Evaluation Of The Nutraceutical Effects Of 3 Types Of Eco-Zonar

(Lactoserum Zonar With Extract Of Zingiber Officinale And Honey) On Healthy Wistar Rats

Ioan Marcus

34. Treatment Of Ligature-Induced Periodontitis In Rats With Natural Revealers And Photodynamic Therapy

Laura Monica Rusu 35. Biocompatibility Evaluation Of The Experimental Dental Composites

Codruta Sarosi 36. Biochemical modifications during pregnancy of patients with miscarriages

Antoaneta Punga

37. Fetal cystic hygromas in first trimester

Antoaneta Punga

38. Management of tubal ectopic pregnancy

Antoaneta Punga

39. The benefits of emotional stimuli in a virtual reality cognitive and motor rehabilitation

Călin Corciovă

40. A comparative study of antitumoral effects of new solid forms of Fluorouracil & Piperazine

Gabriela Chereches

Documents

PROGRAM - event-consulting.roevent-consulting.ro/uploads/files/Program(2).pdfZvezdana Kojic . The 30th Conference of Physiology: ”Integrative physiology – From fundamental mechanisms