Probability and Screen Systems

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  • 8/13/2019 Probability and Screen Systems

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    In electromagnetic systems, the energy per photon = hn.In communication systems, noise can be either quantum or

    additive from the measurement system ( receiver, etc). The noise

    power in a communication system is 4kTB, where k is the

    Boltzman constant,T is the absolute temperature, and B is thebandwidth of the system. When making a measurement (e.g.

    measuring voltage in a receiver) , noise energy per unit time 1/B

    can be written as 4kT.

    The in the denominator comes from the standard deviation of

    the number of photons per time element.

    kThvNNhv

    iseAdditiveNohvNNhvSNR

    4

    Motivation:

    N

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    When the frequency n> hn

    In the X-ray region where frequencies are on the order of 1019, hv

    >> 4kT

    So X-ray is quantum limited due to the discrete number of photons

    per pixel. We need to know the mean and variance of the random

    process that generate x-ray photons, absorb them, and record them.

    kThvN

    Nhv

    iseAdditiveNohvN

    NhvSNR4

    Motivation:

    Recall: h = 6.63x10-34Js

    k = 1.38x10-23J/K

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    Motivation:

    We will be working towards describing the SNR of medical systems

    with the model above. We will consider our ability to detect some

    object ( here shown in blue)that has a different property, in this

    case attenuation, from the background ( shown here in green). To do so,we have to be able to describe the random processes that will

    cause the x-ray intensity to vary across the background.

    I

    Contrast = I / I

    SNR = I / I = CI / I

    I

    Object we are trying to detect

    Background

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    The value of a rolled die is a random process.

    The outcome of rolling the die is a random variable of discrete

    values. Lets call the random variable X. We write then that

    the probability of X being value n is px(n) = 1/6

    1/6

    1 2 3 4 5 6

    Note: Because the probability of all events is equal,we refer to this event as having a uniformprobability

    distribution

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    1/6

    1 2 3 4 5 6

    1

    1 2 3 4 5 6

    Cumulative Probability

    Distribution

    mn

    n

    X

    X

    np

    mnpmF

    stemDiscreteSy

    1

    )(

    ))(()(

    )(npX

    Probability Density Function (pdf)

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    Continuous Random Variables

    pdf is derivative of cumulative density function

    1)(0

    )()(

    /)()(

    xF

    dxxpxF

    dxxdFxp

    X

    XX

    XX

    1. cdf is integral of pdf

    2. cdf must be between 0 and 1

    3. px(x) > 0

    p[x1 X x2] = F(x2) - F(x1) = 2

    1

    )(

    x

    x

    X dxxp

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    Zeroth Order Statistics

    Not concerned with relationship between eventsalong a random process

    Just looks at one point in time or space

    Mean of X, mX,or Expected Value of X, E[X]

    Measures first moment of pX(x)

    Variance of X, 2X, or E[(X-m)2]

    Measure second moment ofpX(x)

    dxxxpXX )(

    m

    std

    dxxpx

    X

    XX

    m )()( 22

    Standard deviation

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    Zeroth Order Statistics

    Recall E[X]

    Variance of X or E[(X-m)2]

    dxxxpX )(

    22222

    222

    222

    22

    ][][][

    ][2][

    )()(2)(

    )()(

    m

    mm

    mm

    m

    XEXEXE

    XEXE

    dxxpdxxpxdxxpx

    dxxpx

    X

    X

    XXXX

    XX

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    p(n) for throwing 2 die

    2 3 4 5 6 7 8 9 10 11 12

    6/36

    1/36

    2/36

    3/36

    4/36

    5/36

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    Fair die

    Each die is independent

    Let die 1 experiment result be x and called Random Variable XLet die 2 experiment result be y and called Random Variable Y

    With independence,

    pXY(x,y) = pX(x) pY(y)

    and E [xy] = xy pXY(x,y) dx dy= x pX(x) dx y pY(y) dy= E[X] E[Y] if x,y independent

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    1. E [X+Y] = E[X] + E[Y] Always2. E[aX] = aE[X] Always

    3. 2x= E[X2]E2[X] Always

    4. 2(aX) = a22x Always

    5. E[X + c] = E[X] + c

    6. Var(X + Y) = Var(X) + Var(Y) only if the X and Yare statistically independent.

    _

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    If experiment has only 2 possible outcomes for each trial,we call it a Bernouli random variable.

    Success: Probability of one is p

    Failure: Probability of the other is 1 - p

    For n trials,

    P[X = i] is the probability of i successes in the n trials

    X is said to be a binomial variable with parameters (n,p)

    ini ppiin

    niXp

    )1(

    !)!(

    !][

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    Roll a die 10 times.

    In this game, you win if you roll a 6.

    Anything else - you lose

    What is P[X = 2], the probability you win twice?

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    Roll a die 10 times.

    6 you win

    Anything else - you lose

    P[X = 2] i.e. you win twice

    = (10! / 8! 2!) (1/6)2(5/6)8

    = (90 / 2) (1/36) (5/6)8= 0.2907

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    If p is small and n large so that np is moderate, then an approximate

    (very good) probability is:

    P[X=i] = e -i / i! Where np =

    With Poisson random variables, their mean is equal to their

    variance!

    E[X] = x2=

    p[X=i] is the probability exactly i events happen

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    Let the probability that a letter on a page is misprinted

    is 1/1600. Lets assume 800 characters per page. Findthe probability of 1 error on the page.

    Binomial Random Variable Calculation.

    P [ X = 1] = (800! / 799!) (1/1600) (1599/1600)799

    Very difficult to calculate some of the above terms.

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    Let the probability that a letter on a page is misprinted

    is 1/1600. Lets assume 800 characters per page. Findthe probability of 1 error on the page.

    P [ X = i] = e -i / i!

    Here i = 1, p = 1/1600 and n =800, so =np =

    So P[X=1] = 1/2 e 0.5= .30

    What is the probability there is

    more than one error per page? Hint:

    Can you determine the probability

    that no errors exist on the page?

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    m m+ m-

    2

    2

    2

    )(

    exp2

    1

    )(

    m

    x

    xpX

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    1) Number of Supreme Court vacancies in a year

    2) Number of dog biscuits sold in a store each day

    3) Number of x-rays discharged off an anode

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    Signal Power

    Noise Power

    If X represents power,

    SNR = E[X]/ x2

    If X represents an amplitude or a voltage, then X2represents power.

    SNR = E[X]/ x

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    X-ray photon

    d

    x

    Light photons

    Scintillating

    material

    High density material

    stop photons through

    photoelectric absorption

    Screen creates light fluorescent photons. These get captured or

    trapped by silver bromide particles on film.

    Film

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    x

    r

    h (r) = h(0) cos3= h(0) x3 / (x2+ r2)3/2

    Since

    h(0) = K/x2 K constant

    x2 inverse falloff

    h (r) = Kx / (x2+ r2)3/2

    )()cos(

    22 rx

    x

    Analysis: First calculate spray of light photons

    from an event at depth x.

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    H1()= F{h(r)}

    = 2 h(r) J0(2r) r dr where h(r) given on previous page0

    H1()= 2Ke-

    2x

    (from a table Hankel transforms)

    H()= H1()= e-2x ( Normalize to DC Value)

    H1(0)

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    H()= H1()= e-2x ( Normalize to DC Value)

    H1(0)

    Notice this depends on x, depth of event into screen.Lets come up with based on the likelihood ofwhere events will occur in the scintillating material.

    F(x) = 1 - e - mx for an infinite screen

    Probability an x-ray photon will interact in distance x

    x

    F(x)

    )(H

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    p(x) = dF(x) / dx = me -mx

    For a screen of thickness d

    F(x) = 1 - e -mx / 1 - e -md , then

    since we are only concerned

    with captured photons

    H(p) = H(,x) p(x) dx

    d

    = (1/ 1 - e -md ) e-2 x me-mxdx

    ]1[)1)(2(

    )( )2( mmm

    m

    dd

    ee

    H

    Typical d = .25 mm, m=15/cm for calcium tungstate screen

    d

    x

    e

    exp

    m

    mm

    1

    )(

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    ]1[)1)(2(

    )( )2( mmm

    m

    d

    d e

    eH

    We would like to describe a figure of merit that would describe

    a cutoff spatial frequency, akin to the bandwidth of a lowpass filter.

    For a typical screen with d approximately .25 mm

    and m=15/cm for a calcium tungstate screen, the bracketed term above

    can be approximated as 1 for spatial frequencies near the cutoff.

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    For moderate k, (i.e. a cutoff frequency)

    Let (1 - e-md) = the capture efficiency of the screen

    Then k m/ (2pk + m)2k pk = (1 - k) m

    For k

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    d1 d2

    phosphor phosphor

    Double

    Emulsion

    filmIntuitively, we would believe this system would work better . Letsanalyze its performance. Let d1+d2= d so we can compare

    performance.

    x

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    H(,x) = e -2(d1-x) for 0 < x < d1

    H(,x) = e -2(xd1) for d1< x < d1+ d2

    d, d2

    H() = (m/ 1- e-md

    ) { e-2(d

    1

    - x)

    e- mx

    dx + e-2(xd

    1

    )

    e- mx

    dx}0 d1

    = (m/ 1- e -md) [ ((e -md1 - e -2d1) / (2- m))+ ((e -md1 - e -(2d2+ md) / (2+ u))]

    Again lets determine a cutoff frequency of k for a low pass filter that

    has a response of H(k) = k,

    If we assume d1 d2= d/2, than we can neglecte -2d, e -2d1, e -2d2 because they will be small even for relatively

    small spatial frequencies. e ud is also small compared toe ud1

    Since (2)2>> u2 istrue for all but lowest frequency, then

    12

    2

    d

    k e

    k

    m

    m

    k

    d

    k ekpH

    m

    mm

    m

    2

    2

    )(

    2

    2

    2

    1

    2

    1

    1

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    Compare this cutoff frequency to the single screen cutoff.

    Concentrate on the factor 2e-md1 ( the new factor from the

    single screen film)

    Since

    With 0.3, improvement is 1.7

    Use improvement to lower dose, quicken exam, improve contrast,

    or some combination.

    )2(2

    1ud

    k ek

    m

    mm

    m

    m

    12

    1222

    1

    1

    12/

    2/

    dd

    d

    d

    eeSo

    e

    e

    Improvement is

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    Assuming a circularly symmetric source,

    Id

    (xd

    , yd

    ) = Kt (xd

    /M, yd

    /M) ** (1/m2) s (rd

    /m) ** h (rd

    )

    Detector response is also circularly symmetric.

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    Id(u,v) = KM2T (Mu,Mv) S(mp) H(p)

    H0(p)

    Spatial frequencies at detectorObject is of interest though

    Id(u/M,v/M) = KM2T (u,v) S((m/M)p) H(p/M)

    Product of 2 Low Pass Filters.

    H0(p) = S [(1-z/d) p ] H ((z/d)p)

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    As z d

    H(p)

    S(0)

    As z 0

    S(p)

    H(0)