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8/13/2019 Probability and Screen Systems
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In electromagnetic systems, the energy per photon = hn.In communication systems, noise can be either quantum or
additive from the measurement system ( receiver, etc). The noise
power in a communication system is 4kTB, where k is the
Boltzman constant,T is the absolute temperature, and B is thebandwidth of the system. When making a measurement (e.g.
measuring voltage in a receiver) , noise energy per unit time 1/B
can be written as 4kT.
The in the denominator comes from the standard deviation of
the number of photons per time element.
kThvNNhv
iseAdditiveNohvNNhvSNR
4
Motivation:
N
8/13/2019 Probability and Screen Systems
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When the frequency n> hn
In the X-ray region where frequencies are on the order of 1019, hv
>> 4kT
So X-ray is quantum limited due to the discrete number of photons
per pixel. We need to know the mean and variance of the random
process that generate x-ray photons, absorb them, and record them.
kThvN
Nhv
iseAdditiveNohvN
NhvSNR4
Motivation:
Recall: h = 6.63x10-34Js
k = 1.38x10-23J/K
8/13/2019 Probability and Screen Systems
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Motivation:
We will be working towards describing the SNR of medical systems
with the model above. We will consider our ability to detect some
object ( here shown in blue)that has a different property, in this
case attenuation, from the background ( shown here in green). To do so,we have to be able to describe the random processes that will
cause the x-ray intensity to vary across the background.
I
Contrast = I / I
SNR = I / I = CI / I
I
Object we are trying to detect
Background
8/13/2019 Probability and Screen Systems
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The value of a rolled die is a random process.
The outcome of rolling the die is a random variable of discrete
values. Lets call the random variable X. We write then that
the probability of X being value n is px(n) = 1/6
1/6
1 2 3 4 5 6
Note: Because the probability of all events is equal,we refer to this event as having a uniformprobability
distribution
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1/6
1 2 3 4 5 6
1
1 2 3 4 5 6
Cumulative Probability
Distribution
mn
n
X
X
np
mnpmF
stemDiscreteSy
1
)(
))(()(
)(npX
Probability Density Function (pdf)
8/13/2019 Probability and Screen Systems
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Continuous Random Variables
pdf is derivative of cumulative density function
1)(0
)()(
/)()(
xF
dxxpxF
dxxdFxp
X
XX
XX
1. cdf is integral of pdf
2. cdf must be between 0 and 1
3. px(x) > 0
p[x1 X x2] = F(x2) - F(x1) = 2
1
)(
x
x
X dxxp
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Zeroth Order Statistics
Not concerned with relationship between eventsalong a random process
Just looks at one point in time or space
Mean of X, mX,or Expected Value of X, E[X]
Measures first moment of pX(x)
Variance of X, 2X, or E[(X-m)2]
Measure second moment ofpX(x)
dxxxpXX )(
m
std
dxxpx
X
XX
m )()( 22
Standard deviation
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Zeroth Order Statistics
Recall E[X]
Variance of X or E[(X-m)2]
dxxxpX )(
22222
222
222
22
][][][
][2][
)()(2)(
)()(
m
mm
mm
m
XEXEXE
XEXE
dxxpdxxpxdxxpx
dxxpx
X
X
XXXX
XX
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p(n) for throwing 2 die
2 3 4 5 6 7 8 9 10 11 12
6/36
1/36
2/36
3/36
4/36
5/36
8/13/2019 Probability and Screen Systems
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Fair die
Each die is independent
Let die 1 experiment result be x and called Random Variable XLet die 2 experiment result be y and called Random Variable Y
With independence,
pXY(x,y) = pX(x) pY(y)
and E [xy] = xy pXY(x,y) dx dy= x pX(x) dx y pY(y) dy= E[X] E[Y] if x,y independent
8/13/2019 Probability and Screen Systems
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1. E [X+Y] = E[X] + E[Y] Always2. E[aX] = aE[X] Always
3. 2x= E[X2]E2[X] Always
4. 2(aX) = a22x Always
5. E[X + c] = E[X] + c
6. Var(X + Y) = Var(X) + Var(Y) only if the X and Yare statistically independent.
_
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If experiment has only 2 possible outcomes for each trial,we call it a Bernouli random variable.
Success: Probability of one is p
Failure: Probability of the other is 1 - p
For n trials,
P[X = i] is the probability of i successes in the n trials
X is said to be a binomial variable with parameters (n,p)
ini ppiin
niXp
)1(
!)!(
!][
8/13/2019 Probability and Screen Systems
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Roll a die 10 times.
In this game, you win if you roll a 6.
Anything else - you lose
What is P[X = 2], the probability you win twice?
8/13/2019 Probability and Screen Systems
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Roll a die 10 times.
6 you win
Anything else - you lose
P[X = 2] i.e. you win twice
= (10! / 8! 2!) (1/6)2(5/6)8
= (90 / 2) (1/36) (5/6)8= 0.2907
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If p is small and n large so that np is moderate, then an approximate
(very good) probability is:
P[X=i] = e -i / i! Where np =
With Poisson random variables, their mean is equal to their
variance!
E[X] = x2=
p[X=i] is the probability exactly i events happen
8/13/2019 Probability and Screen Systems
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Let the probability that a letter on a page is misprinted
is 1/1600. Lets assume 800 characters per page. Findthe probability of 1 error on the page.
Binomial Random Variable Calculation.
P [ X = 1] = (800! / 799!) (1/1600) (1599/1600)799
Very difficult to calculate some of the above terms.
8/13/2019 Probability and Screen Systems
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Let the probability that a letter on a page is misprinted
is 1/1600. Lets assume 800 characters per page. Findthe probability of 1 error on the page.
P [ X = i] = e -i / i!
Here i = 1, p = 1/1600 and n =800, so =np =
So P[X=1] = 1/2 e 0.5= .30
What is the probability there is
more than one error per page? Hint:
Can you determine the probability
that no errors exist on the page?
8/13/2019 Probability and Screen Systems
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m m+ m-
2
2
2
)(
exp2
1
)(
m
x
xpX
8/13/2019 Probability and Screen Systems
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1) Number of Supreme Court vacancies in a year
2) Number of dog biscuits sold in a store each day
3) Number of x-rays discharged off an anode
8/13/2019 Probability and Screen Systems
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Signal Power
Noise Power
If X represents power,
SNR = E[X]/ x2
If X represents an amplitude or a voltage, then X2represents power.
SNR = E[X]/ x
8/13/2019 Probability and Screen Systems
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X-ray photon
d
x
Light photons
Scintillating
material
High density material
stop photons through
photoelectric absorption
Screen creates light fluorescent photons. These get captured or
trapped by silver bromide particles on film.
Film
8/13/2019 Probability and Screen Systems
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x
r
h (r) = h(0) cos3= h(0) x3 / (x2+ r2)3/2
Since
h(0) = K/x2 K constant
x2 inverse falloff
h (r) = Kx / (x2+ r2)3/2
)()cos(
22 rx
x
Analysis: First calculate spray of light photons
from an event at depth x.
8/13/2019 Probability and Screen Systems
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H1()= F{h(r)}
= 2 h(r) J0(2r) r dr where h(r) given on previous page0
H1()= 2Ke-
2x
(from a table Hankel transforms)
H()= H1()= e-2x ( Normalize to DC Value)
H1(0)
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H()= H1()= e-2x ( Normalize to DC Value)
H1(0)
Notice this depends on x, depth of event into screen.Lets come up with based on the likelihood ofwhere events will occur in the scintillating material.
F(x) = 1 - e - mx for an infinite screen
Probability an x-ray photon will interact in distance x
x
F(x)
)(H
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p(x) = dF(x) / dx = me -mx
For a screen of thickness d
F(x) = 1 - e -mx / 1 - e -md , then
since we are only concerned
with captured photons
H(p) = H(,x) p(x) dx
d
= (1/ 1 - e -md ) e-2 x me-mxdx
]1[)1)(2(
)( )2( mmm
m
dd
ee
H
Typical d = .25 mm, m=15/cm for calcium tungstate screen
d
x
e
exp
m
mm
1
)(
8/13/2019 Probability and Screen Systems
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]1[)1)(2(
)( )2( mmm
m
d
d e
eH
We would like to describe a figure of merit that would describe
a cutoff spatial frequency, akin to the bandwidth of a lowpass filter.
For a typical screen with d approximately .25 mm
and m=15/cm for a calcium tungstate screen, the bracketed term above
can be approximated as 1 for spatial frequencies near the cutoff.
8/13/2019 Probability and Screen Systems
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For moderate k, (i.e. a cutoff frequency)
Let (1 - e-md) = the capture efficiency of the screen
Then k m/ (2pk + m)2k pk = (1 - k) m
For k
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d1 d2
phosphor phosphor
Double
Emulsion
filmIntuitively, we would believe this system would work better . Letsanalyze its performance. Let d1+d2= d so we can compare
performance.
x
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H(,x) = e -2(d1-x) for 0 < x < d1
H(,x) = e -2(xd1) for d1< x < d1+ d2
d, d2
H() = (m/ 1- e-md
) { e-2(d
1
- x)
e- mx
dx + e-2(xd
1
)
e- mx
dx}0 d1
= (m/ 1- e -md) [ ((e -md1 - e -2d1) / (2- m))+ ((e -md1 - e -(2d2+ md) / (2+ u))]
Again lets determine a cutoff frequency of k for a low pass filter that
has a response of H(k) = k,
If we assume d1 d2= d/2, than we can neglecte -2d, e -2d1, e -2d2 because they will be small even for relatively
small spatial frequencies. e ud is also small compared toe ud1
Since (2)2>> u2 istrue for all but lowest frequency, then
12
2
d
k e
k
m
m
k
d
k ekpH
m
mm
m
2
2
)(
2
2
2
1
2
1
1
8/13/2019 Probability and Screen Systems
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Compare this cutoff frequency to the single screen cutoff.
Concentrate on the factor 2e-md1 ( the new factor from the
single screen film)
Since
With 0.3, improvement is 1.7
Use improvement to lower dose, quicken exam, improve contrast,
or some combination.
)2(2
1ud
k ek
m
mm
m
m
12
1222
1
1
12/
2/
dd
d
d
eeSo
e
e
Improvement is
8/13/2019 Probability and Screen Systems
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Assuming a circularly symmetric source,
Id
(xd
, yd
) = Kt (xd
/M, yd
/M) ** (1/m2) s (rd
/m) ** h (rd
)
Detector response is also circularly symmetric.
8/13/2019 Probability and Screen Systems
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Id(u,v) = KM2T (Mu,Mv) S(mp) H(p)
H0(p)
Spatial frequencies at detectorObject is of interest though
Id(u/M,v/M) = KM2T (u,v) S((m/M)p) H(p/M)
Product of 2 Low Pass Filters.
H0(p) = S [(1-z/d) p ] H ((z/d)p)
8/13/2019 Probability and Screen Systems
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As z d
H(p)
S(0)
As z 0
S(p)
H(0)