Prevention of Early Menopause Study<br />(POEMS)-S0230<br /> Phase III trial of LHRH analog during chemotherapy to reduce ovarian failure in early stage, hormone receptor-negative breast cancer: an international Intergroup trial of SWOG, IBCSG, ECOG, and CALGB (Alliance)

Presented By Halle Moore at 2014 ASCO Annual Meeting

Background

Presented By Halle Moore at 2014 ASCO Annual Meeting

Ovarian Protection with LHRH analog

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS/S0230 Schema

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Objectives and Endpoints

Presented By Halle Moore at 2014 ASCO Annual Meeting

Goserelin Administration

Presented By Halle Moore at 2014 ASCO Annual Meeting

Patient Eligibility

Presented By Halle Moore at 2014 ASCO Annual Meeting

Statistical Considerations

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Consort Diagram

Presented By Halle Moore at 2014 ASCO Annual Meeting

Patients

Presented By Halle Moore at 2014 ASCO Annual Meeting

Endocrine Toxicity

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Ovarian Failure

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Secondary Ovarian Outcomes

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Pregnancy

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Disease Free Survival

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS Overall Survival

Presented By Halle Moore at 2014 ASCO Annual Meeting

POEMS

Presented By Halle Moore at 2014 ASCO Annual Meeting

Conclusions

Presented By Halle Moore at 2014 ASCO Annual Meeting

Acknowledgements

Presented By Halle Moore at 2014 ASCO Annual Meeting