Precision Oncology powered by Genomics, NGS & Liquid Biopsy

Comprehensive genome profiling is here to help bring improvements in cancer management by enabling precision oncology. Through convergent biosciences and technologies, Next Generation Sequencing(NGS) powers rapid and sensitive tumor DNA sequencing for the analysis and comprehension of the driver mutations of the oncogenic signaling pathways causing cancers. The information can be used to highlight all these at once:

• Predictive Biomarkers• Prognositic Biomarkers• Therapeutic Response Biomarkers• Therapeutic Resistance Biomarkers• Genetic Biomarkers for Targeted Therapies (>100)• Early Detection Biomarkers• Monitor tumor burden• Monitor minimal residual disease• Monitor intra and inter tumoral heterogeneity

Massive Genomics offers cancer genome profiling services on solid tumor biopsies (FNA/Core biopsy/FFPE) and on LIQUID BIOPSIES (Whole Blood circulating tumor DNA assay) for solid tumor cancers and leukemias in adults and children. We check for both Germline and Somatic genetic variants.

The ctDNA Liquid Biopsy offers several noteworthy applications & benefits:• Early detection• Assessment of molecular heterogeneity of overall disease• Monitoring of tumor dynamics• Identification of genetic determinants for targeted therapy• Evaluation of early treatment response of any type• Monitoring of minimal residual disease after surgery, radio, chemo etc• Assessment of evolution of resistance in real time• Non-invasive & Easily repeatable for monitoring purposes• Short turnaround time for swift decision making (7 working days)

• Cost effective & Comprehensive - simultaneous test of many clinically significant cancer biomarkers

We enable you to track the oncogenic driver variants and stratify cancer by the molecular/genomic subtypes accordingly through massive parallel sequencing of the relevant genes and genomic big data analysis methods.

The genes of focus are of clinical relevance and have been cited in many journals, papers, EMA, FDA, ESMO and NCCN.

Left: Some driver variants we test for and their signalling pathways.

The technology has been used to sequence the genomes of thousands of cancers. Therefore our panels focus on those variants that are associated with malignant tumors that have been clinically diagnosed and with clinical relevance.

We can detect various types of clinically relevant genomic alterations by sequencing both DNA and RNA:• SNVs(Single Nucleotide Variants)• CNVs(Copy Number Variants)• Fusions

Our platform gives you the opportunity to embark on the next generation of research, tools and regimens that will win in this fight against cancer.

Massive Genomics Solutions LTD2nd Floor, Landmark Plaza,

Argwings Kodhek,Opposite The Nairobi Hospital.

Email: info@massivegenomics.co.keTel: +254 (0) 700 362 362

FB: Massive genomicsTwitter: @genomicskenya

Dedicated to improving clinical cancer outcomes and enhancing oncology research

through cancer genome profiling.

Images Courtesy of The Cancer Genome Atlas & Journal of Clinical Oncology, Swiss integrative Center for Human Health, Mary Crowley Cancer Research Center

Together in the fight against cancer!!!

PLEASE CONTACT US FOR ANY QUERIES

Apart from providing the molecular evidence behind tumors, we also provide bioinformatic services. Each assay is statistically verified with various bioinformatic tools and the data cross linked with global cancer knowledge bases like ONCOMINE® KNOWLEDGEBASE REPORTER to provide up to date information on a particular variant and relevant therapies.

The therapies may be approved by FDA or EMA or be under clinical trial. They may also be on the guidelines of NCCN and ESMO or not. All this information we believe will be able to help you stay on top of the fight against cancer.

Cancer genome analysis via circulating tumor DNA Liqud Biopsy will enable us to improve overall survival while reducing the overall cost of treatment for the patients, their families and the public health system.

Order for a Liquid Biopsy kit from any location

Using Cell-Free DNA BCT® | Streck tubes

Using these special tubes we can afford an individual/patient the convenience of not having to travel to our lab or a to far away facility for the genomic profiling services. Just order for a kit and send it back to us for the Liquid biopsy ctDNA Assay for a comprehensive cancer genome analysis.