Hompes MethodPractitioner Training Level II

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Lesson Seven

Part C – Genova Interpretation

GDx – GI Effects

• The Genova Diagnostics GI Effects test is an evolved version of the old Metametrix GI Effects panel. It uses a mix of PCR analysis for bugs, chemistry analysis and standard ova and parasite microscopy.

GDx – GI Effects

• We haven’t used many of these tests, but some of our clients come to us having performed one of the panels. As such we’re quite familiar with the test.

• Furthermore, some of the markers have been carried over from the old Metametrix version.

GDx – GI Effects

• Because the parasite and fungal analyses are performed using microscopy, the test requires 3 samples, making less convenient for people.

GDx – GI Effects

• I didn’t like the way Genova conducted their business during the takeover of Metametrix, so I’m slightly biased against them. But PLEASE don’t let that sway your opinion.

GDx – GI Effects

• The GI Effects as some excellent features that provide great information for you as a practitioner, and for your clients and patients.

• Remember that Genova is the market leader, so using their tests can help with credibility.

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

• Diversity Association is graphically represented on a lower to higher overall diversity.

• In the gut, higher diversity is associated with gut health.

GDx – GI Effects

• A Diversity Association indicator in the lower half of the graphical bar indicates a high likelihood that a patient’s gut is not healthy.

• A Diversity Association in the upper quartile of the graphical bar indicates high likelihood that a patient’s gut is healthy.

GDx – GI Effects

• The Relative Abundance (RA) graphic is a visual representation of the proportion of each assayed commensal target — grouped into their respective phyla — relative to:

• The sum total of all commensal targets measured

• The composite results of a healthy cohort

GDx – GI Effects

• The relative abundance of each phylum represented in the patient’s sample is expressed as a stacked bar graphic, shown in comparison to the composite levels seen in a healthy cohort. The Relative Abundance results (combined with the Diversity Association results) serve as global markers of gut health status and microbial balance.

GDx – GI Effects

• Although each individual has a unique set of bacteria, comparison of the RA at the level of the phyla for an individual against a characterized healthy cohort can support effective clinical interventions, particularly in those individuals with a pronounced imbalance.

GDx – GI Effects

• Significantly lower total RA (compared to healthy cohort) may represent gut microbiota imbalance due to low beneficial commensal organisms.

• Significantly higher total RA (compared to healthy cohort) may represent gut microbiota imbalance due to microbial overgrowth.

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

GDx – GI Effects

Thank You!

• As always, thanks a million for tuning in and consuming this info. I hope you’ve enjoyed learning about three of the best stool tests on the market, and how to interpret them. In the next module, we’ll look at how to create programmes that resolve the problems found in the test!