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2025 Milestones Prevent cancers. Save lives. Eliminate suffering. Possible ALBERTA’S CANCER FREE FUTURE ALBERTA CANCER BOARD AND FOUNDATION ANNUAL REVIEW 2005/2006

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2025 Milestones Prevent cancers. Save lives. Eliminate suffering.

PossibleALBERTA’S CANCER FREE FUTUREA l b e r tA C A n C e r b oA r d A n d F o u n dAt i o n A n n uA l r e v i e w 2 0 0 5 / 2 0 0 6

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2025 Milestones Prevent cancers. Save lives. Eliminate suffering.

by 2025, the Alberta Cancer board and Foundation, in collaboration with Alberta’s health, research, government and not-for-profit sectors, is committed to:

Preventing more than 61,000

cancers by reducing the projected

cancer incidence 35 per cent

Saving more than 45,000 lives by

reducing projected mortality 50

per cent

Working to eradicate suffering

in all its forms, so any day spent

living with cancer can still be a

day spent fully alive.

Cover Photo: Brendan O’Callaghan, Leukemia Survivor

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Alberta Cancer Boardboard of directors, 2005/2006Gary G. Campbell, Q.C., Chair, EdmontonJ.W. (Jack) Halpin, Vice-Chair, Calgary

Jean M. Agrios, EdmontonAllan Hargreaves, CalgaryPatricia L. Jones, EdmontonRichard K. Melchin, CalgaryIrene Nicolson, Grande PrairieMary O’Neill, EdmontonBrian Rogers, Q.C., CalgaryCatherine Roozen, EdmontonBronwyn Shoush, Edmonton

Alberta Cancer Foundation trustees, 2005/2006Pattie Culver, Chair, CalgaryDoug Cumming, Vice-Chair, Edmonton

Mary Barr, CalgaryMarc Bombenon, CalgaryGreg Cameron, Edmonton Gary G. Campbell, Q.C., EdmontonGordon Ganong, Red DeerBrian Rogers, Q.C., Calgary Sandy Slator, Chair, 2006/2007, EdmontonDr. Jean-Michel Turc, Edmonton

Corporate ExecutiveDr. Jean-Michel Turc,

President & CEO, Alberta Cancer Board

Mr. Aslam Bhatti, Vice-President Operations

Dr. George Browman, Vice-President & Director, Tom Baker Cancer Centre

Dr. Heather Bryant, Vice-President & Director,Division of Population Health & Information

Dr. Carol Cass, Vice-President & Director, Cross Cancer Institute

Dr. Tony Fields, Vice-President Medical Affairs & Community Oncology

Dr. Cyril Kay, Vice-President Research

Linda Mickelson, CEO, Alberta Cancer Foundation

Alberta’s Cancer Free Future . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4

Milestone onePrevent Cancers . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5The Tomorrow Project . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6Uncovering the Preventive Power of Exercise . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8Con Amore . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10Interpreting Radiation’s Impact . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12Tests You Should Take . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13Fall of Destiny . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14Mary’s Legacy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16

Milestone twoTargeting Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18Save Lives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19Each Day Fully Lived . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20Keeping Her Head Up . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22From Their Hearts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24Searching for the Best Solution . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26Computer-Designing Cancer Treatment . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28

Milestone three Eliminate Suffering . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29Finding Voice . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .30Managing Pain . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .32Resolved to Make an Impact . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .34

Demonstrated Care . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .36Thank you . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .37Special events . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .46

The Alberta Cancer Board is committed to a leadership role to reduce the burden of cancer through excellence in prevention, screening, diagnosis, treatment, palliation, education and research.

The Alberta Cancer Foundation raises and receives funds on behalf of the Alberta Cancer Board. Alberta Cancer Foundation funding supports patient programs, equipment purchase and cancer care across Alberta; approximately 70 per cent of Alberta Cancer Foundation funding goes to cancer research.

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Gary G. Campbell, Q.C. Chair, Alberta Cancer Board Trustee, Alberta Cancer Foundation

Jean-Michel Turc President and CEO, Alberta Cancer Board Trustee, Alberta Cancer Foundation

The first thing these patients and their families want is to be cancer free. The second thing is to ensure others are spared the experience.

Both are becoming possible. Cancer is a familiar adversary, evident in some of the earliest archeological remnants of the human race. Yet we live in a time when knowledge doubles every 18 months.

We now know how to prevent most cancers. We know how to cure some cancers and how to extend the lives of people afflicted with others. We know how to support those with cancer in a way that ensures freedom from suffering. And research is teaching us more each day.

That is why the Alberta Cancer Board has absolute confidence in its vision for a Cancer Free Future and in its ability to achieve the measurable milestones it set for the year 2025. Between now and then, the Alberta Cancer Board, in collaboration with Alberta’s health, research, government and not-for-profit sectors, is committed to:

• Preventing more than 61,000 cancers by reducing the projected cancer

incidence 35 per cent

• Saving more than 45,000 lives by reducing projected mortality 50 per cent

• Working to eradicate suffering in all its forms, so any day spent living with

cancer can still be a day spent fully alive.

There is a great deal of work ahead. But Alberta has an important resource with the establishment this year of the Alberta Cancer Prevention Legacy Act, a $500 million endowment, which will invest roughly $25 million each year in research and prevention. The Alberta Cancer Foundation and the Alberta Cancer Board have committed to matching these funds through philanthropic dollars, research grants and contracts. Full financials for the 2005/2006 year are available on our website at albertacancer.ca.

This investment will move Alberta closer to a Cancer Free Future as the Alberta Cancer Board works with our partners throughout the province to integrate and strengthen cancer research; to coordinate and expand cancer screening programs; and to extend patient care to fully address the physical, mental and emotional effects of cancer.

Today, cancer is an all-too-present reality, and Alberta will be challenged to keep up with the cancer treatment needs of a growing and aging population. For too many Albertans, cancer will continue to be personal. The Alberta Cancer Board will support these Albertans with the best treatment and care possible, while working to ensure Alberta moves measurably closer to the Cancer Free Future on the horizon.

Alberta’s Cancer Free Future it’s Personal, it’s Possible.

Currently, 81,000 Albertans are

living with cancer. For each of

these people, cancer is personal.

These are mothers, fathers,

sons and daughters. These are

friends, fishing buddies and

colleagues. These pages contain

some of their stories and those

of the researchers and medical

professionals working to

support them.

These are stories of courage,

triumph and loss. The Alberta

Cancer Board is privileged to

be the agency responsible for

ensuring that these people

—and all Albertans living

with cancer—receive the

highest standard of treatment

and care based solidly

on research evidence. And the

Alberta Cancer Foundation

is privileged to partner with

thousands of its donors in support

of the Alberta Cancer Board’s work.

Alberta Cancer board and Foundation 2005/2006�

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The Alberta Cancer Board’s 2025 milestones—to reduce the projected incidence of cancer by 35 per cent, to reduce projected mortality rates by 50 per cent and to eradicate patient suffering—may seem unrealistic at first glance. But Dr. Heather Bryant, vice-president and chief information officer of the Alberta Cancer Board and director of the Division of Population Health and Information, says people expect a single breakthrough will lead to success. The truth is, success will come from a combination of prevention, early detection and treatment, and improved patient care, all underscored by new information and research findings.

“If you look at lung cancer deaths now compared to what they would have been had we not reduced smoking rates, you can already see success,” says Bryant. “We need to apply the same multifaceted approach to other cancers. Information on weight control, the risks of sun exposure, the value of increasing

fruit and vegetable intake, the value of physical activity and alcohol in moderation—these are all messages that we need to connect to reducing the incidence of cancer.”

Getting this information out is important, says Bryant, but preaching about it is not what people need. “There are very few people who do not know that smoking is bad for them now, or that exercising is good.” Instead, we need to give people the tools they need to be health wise. “Part of it is education, part of it is working to provide healthier alternatives,” says Bryant.

Alberta lists 13,000 new cases of cancer each year; this number is predicted to double to 26,000 by 2025. If 50 per cent of cancer can be prevented by adopting healthier choices and improving testing for cancer, that increase can be kept in check. It is the key to achieving a cancer free future.

Prevent CancersPrevent Cancers“ if you look at lung cancer deaths now compared to what

they would have been had we not reduced smoking rates, you can already see success.” –Dr.Heather Bryant

Milestone one

OneStepping up to Alberta’s Cancer Free Future �

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Most of us take tomorrow for granted, until a diagnosis of cancer. Then, tomorrow becomes ambiguous, a mixture of fear, uncertainty, hope and promise.

Thanks to tens of thousands of Albertans, The Tomorrow Project is working to uncover the secrets to a cancer free future. This Alberta Cancer Board project, funded in part by the Alberta Cancer Foundation, aims to accurately assess the environmental, personal and behavioural causes of cancer.

Since October 2000, researchers at The Tomorrow Project have been quietly at work gathering participants. “We originally enrolled 12,000 people, and added another 6,000 over six years,” says Dr. Heather Bryant, principal investigator. “By the end of 2007, we expect to have a total cohort of 30,000.” Their goal is 50,000 Albertans ranging in age from 35 to 69, rural and urban, from every economic class, ethnic and racial group, all without a previous cancer diagnosis.

The study group will be followed to the age of 85 or death, so agreeing to participate is a long-term commitment. Each year, participants spend two hours filling out surveys of their lifestyle, diet and physical activity.

“It amazes me so many people agree to be part of this,” says Paula Robson, project director. “Few people drop out, most want to help beat cancer any way they can.”

Over the period of the project, some participants will develop cancer, and data collected prior to their diagnoses will help assess what factors may have played a role.

In future, researchers also hope to collect blood samples from participants. “This would be a fantastic resource,” says Robson. “Bloods can tell us so much about what is going on. Blood work taken during healthy years may be able to tell us the story about what changed if an individual then develops cancer or some other chronic disease.”

For Maxine Mendritzki, a participant since 2005, the call was an invitation to do something meaningful. “It feels good to contribute your time and information this way for cancer research. I am really looking forward to hearing about their findings in years to come.”

Another random-dialing telephone recruitment for The Tomorrow Project is under way. You might just get a call….

the tomorrow ProjectAlberta’s living lab for Cancer research

Prevent cancers. Save lives. Eliminate suffering.

the tomorrow Project aims to collect information from

50,000 Albertans over a 50-year period. the wealth of

data on such a large group of healthy Albertans will

provide clues on what goes wrong when cancer or some

other chronic disease later develops.

Alberta Cancer board and Foundation 2005/2006�

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Molly Kirkpatrick from Lloydminster will benefit from the data collected in The Tomorrow Project.

Stepping up to Alberta’s Cancer Free Future �

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uncovering the Preventive Power of exercise

First she helped demonstrate that physical activity could significantly reduce breast cancer risk. Now the Alberta Cancer Board’s Dr. Christine Friedenreich is studying the role diet, physical activity and other lifestyle factors have on endometrial cancer risk and survival. A questionnaire she developed to measure lifetime physical activity is also being used to assess the effects of activity on prostate cancer.

“We’ve known for a long time that physical activity is important in reducing a lot of chronic conditions, including cardiovascular disease, diabetes, osteoporosis, hypertension and mental illness,” says Friedenreich. “Now, a number of cancers are being added to that list. For many people, that’s a positive and empowering message.”

Endometrial, or uterine, cancer is the fourth most common type of cancer among Canadian women yet little is known about its cause. Friedenreich hopes to increase understanding of the causes and learn how the risk of developing this disease can be reduced.

Her research team has spent five years interviewing 1,500 women—those with the illness and a control group—about their risk factors for endometrial cancer.

“We looked at anything related to the risk of getting cancer over a lifetime—physical activity, diet, smoking, reproductive and hormone use history, alcohol consumption, family history of cancer, medical history—just about everything,” says Friedenreich, a leader in the field of cancer epidemiology.

Dr. Christine Friedenreich is investigating how lifestyle affects endometrial cancer risk.

Physical activity is known to reduce cardiovascular disease,

diabetes, osteoporosis, hypertension and other chronic

illnesses. now a number of cancers are being added to the

list of conditions favourably impacted by exercise.

research

A three-year study begun in 1995 by researcher

dr. Christine Friedenreich found that post-menopausal

women who are physically active had a 30 per cent reduced

risk of breast cancer compared to those who are not. It also

found that even women who only get fit after they go through

menopause have a better chance of staying healthy.

“it is never too

late to start being

physically active.”

–Dr. Christine

Friedenreich

Alberta Cancer board and Foundation 2005/2006�

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Today’s ResearchersThirty years ago we barely knew the origins of cancer. Today, thanks to research, improved technologies and an explosion of genomic information, we have a much better idea of cancer’s molecular structure. Dr. Cyril Kay, Alberta Cancer Board’s vice-president of research, says eventually we will describe and identify all cancers in molecular terms, leading to improvements in the way cancer is detected, classified, monitored and treated.

“We can already demonstrate increases in five-year survival rates for many cancers,” says Kay. “We have finely targeted therapies with mild side-effects for a number of cancers. And we have made improvements in the lives of people living with advanced cancer by better treating their symptoms.”

A good part of research activity has been involved in finding the damaged genes and proteins within cancer cells. In so doing, we find new ways to treat the disease. New types of therapeutic drugs can be designed to attack these damaged molecules and change the course of the cancer.

This is just one of a number of various techniques that will achieve the medical promise of a new era in cancer prevention and treatment. “Cancer is a complex problem with hundreds of forms,” Kay says. “There are many ways of controlling it and all its burdens.”

The task is not trivial, he admits, but developments are occurring fast and furiously. “There is absolutely a sense of momentum amongst our researchers today,” says Kay.

Calgary

Nizar J. BahlisOliver F. Bathe

Gwyn BebbShirin Bonni

George BrowmanChristopher B. Brown

Heather E. BryantDouglas J. Demetrick

Peter DunscombeChristine Friedenreich

Donald J. FujitaZu-Hua GaoNeil Hagen

Frank R. JirikSusan P. Lees-MillerAnthony Magliocco

Ian F. ParneyDerrick Rancourt

Stephen M. RobbinsColum SmithWendy Smith

David SpencerJan Storek

Dallan B.Young

edmonton

Bassam AbdulkarimShairaz BakshVickie Baracos

Robert CampbellLinda E. Carlson

Carol E. CassGordon K.T. Chan

Sambasivarao DamarajuMark Glover

Roseline GodboutDennis Hall

Michael J. HendzelMary Hitt

Piyush KumarRaymond Lai

John R. MercerDavid Murray

Matthew ParliamentManijeh Pasdar

Robert G. PearceyLinda M. Pilarski

Tony ReimanRonald S. Sloboda

James C. StoneMichael Symlie

Mavanur R. SureshKatia TonkinJoan Turner

Jacek TuszynskiD. Alan UnderhillMichael WeinfeldLeonard I. Wiebe

Wilson H. Roa

lethbridge

Olga Kovalchuk

“No other studies have measured physical activity beginning in childhood to the time of diagnosis. We are the first in the world to measure lifetime physical activity.”

On top of the unique database the research team is compiling, Friedenreich will be analyzing stored frozen blood samples collected from study participants to compare lipid, hormone and other biomarker levels. The aim is to understand which biological mechanisms explain how risk factors, such as physical activity, influence endometrial cancer risk.

“Since these lifestyle risks are modifiable, the public health potential of this research is considerable,” she says. “I think there is an increased understanding that lifestyle and exercise is a way women can take control of their lives and reduce their morbidity, but we still have a way to go.”

This project should provide clues into how exercise wards off the disease, what types of exercise might be the most effective and when it should be undertaken.

Maximizing Research The focus of the Alberta Cancer Board extends beyond patient care and treatment—it also includes a firm commitment to research. Research will help us understand why cancer occurs and identify more effective detection and treatment strategies.

Establishment of the Alberta Cancer Research Institute, a partnership between the Alberta Cancer Board and the Universities of Alberta and Calgary will, in future, coordinate all cancer research in the province. The Institute will build on areas of existing research strength in Alberta and on national priorities. This integration of cancer research in Alberta will maximize research resources and talent and enhance Alberta’s position as a leader in cancer knowledge.

Research Partners Each year the Alberta Cancer Board funds millions of dollars in cancer research in Alberta. In 2005/2006 it distributed over $16 million to cancer research; more than one-third of these research funds were provided by the Alberta Cancer Foundation. Its affiliates and medical research funding partners include the Canadian Institutes of Health Research, the National Cancer Institute of Canada, and the Canada Foundation for Innovation. The Government of Alberta and its health-related ministries, Alberta’s three research-based universities—the Universities of Alberta, Calgary and Lethbridge—and the Alberta Heritage Foundation for Medical Research are all key to developing Alberta as a world leader in cancer research.

Alberta Cancer Board Researchers Awarded in

the 2005/2006 Fiscal YearThe following researchers were awarded

Alberta Cancer Board and Foundation funds in the 2005/2006 fiscal year:

Stepping up to Alberta’s Cancer Free Future �

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Prevent cancers. Save lives. Eliminate suffering.

In May 2006, after months of coughing and three X-rays charting what his doctor thought was pneumonia, Giulio Salvia, age 68 years, was diagnosed with stage three lung cancer. His oncologist was optimistic about treatment, until the discovery of a cancerous growth on his forehead indicated the cancer had spread and forced a change of plans. “It is tough to remain optimistic when you don’t get any good news,” says his daughter Adriana Salvia. She has her moments of breakdown, always outside of her dad’s range. “He needs to remain optimistic to deal with this.”

Giulio quit smoking more than 10 years ago. When he began smoking as a young man, there was little information about its harmful effects. We know now that more than 80 per cent of lung cancer is directly attributable to smoking, but that is little comfort to a man facing his own mortality, or to a family coping with the loss of a husband and father they love. “People think of lung cancer as your own fault,” says Adriana. “There is a real stigma around it, and that is hard to handle on top of dealing with the cancer itself.”

Adriana, her sisters Adelia and Julia, and their mother, Natala, have banded together to support Giulio. Decisions about treatment and care are made jointly, and if one person does not agree, they look for solutions they can

all be comfortable with. It comes down to one question, always the same one, says Adriana: “How do we preserve my dad’s dignity in the whole process?”

Adriana has armed herself with as much information as she can on everything from diet to homeopathic treatments to support services the family can draw on when needed. “Maybe it’s selfish,” she says, “I wanted to feel that I had done everything I could to keep him around as long as possible with the best life possible.” When Giulio reached his limit for radiotherapy and chemotherapy treatments, the family decided to try IV delivery of high doses of Vitamin C at a private clinic. “You need to do whatever you can, and we felt this could not

hurt,” Adriana says. “At least he’s not catching any colds!”

The family hopes Giulio will get strong enough to go for physiotherapy and perhaps regain his appetite. They would like to alleviate the terrible cough that keeps him awake at night and wracks his body to exhaustion. They would love to see him laugh, enjoy his grandchildren and stop thinking about the spectre of his own death. They are talking about making funeral plans now, so that their mother is not overwhelmed with details later.

They are showing their father every day what his life has meant to them, and coping as best they can, given the circumstances.Giulio Salvia died in Edmonton on September 16, 2006.

Con Amorewith love

the Alberta Cancer board offers a smoking cessation program at both the Tom Baker Cancer Centre in Calgary and the Cross Cancer Institute in Edmonton. The program is also available via Telehealth video to residents of the Chinook, Aspen, Northern Lights and Palliser Health Regions. The program has been offered through the Tom Baker Cancer Centre since 1983 and to date has helped over 6,000 people quit smoking. Contact your regional health authority for more information.

tobacco use is responsible for 30 per cent of cancer deaths and is implicated in nearly 85 per cent of lung cancer cases. It is the leading cause of preventable deaths for Albertans over the age of 12. There is help for those who want to quit, and immediate health benefits.

In 2001, the Alberta Alcohol and Drug Abuse Commission (AADAC) launched a province-wide tobacco cessation line. Callers receive information about tobacco cessation programs across Alberta along with support and encouragement. For help quitting call AADAC toll free at 1-866-33AADAC or go to www.albertaquits.ca.

Alberta Cancer board and Foundation 2005/200610

Killing the Habit that Kills

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Lung Cancer

Incidence 2003 Mortality 2003

881 Male 733 Male

730 Female 556 Female

1611 Total 1289 Total

Adriana Salvia with a photo of her father Giulio Salvia. Giulio was diagnosed with

lung cancer in the spring of 2006.

Sometimes Adriana Salvia

sees into her father’s

heart through his eyes:

“i can see him thinking

‘what if i had never

smoked? would i be in

this position now?’”

Stepping up to Alberta’s Cancer Free Future 11

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interpreting radiation’s impactdr. olga Kovalchuk was witness to the devastation of the

Chernobyl nuclear disaster. Her research is now focused on

finding ways to block the harmful effects of radiation while

mining its strength in attacking cancer.

research

dr. olga Kovalchuk was

a high-school student in

Ukraine in April 1986 when

the worst nuclear accident

in history occurred at

the Chernobyl plant, 600

kilometres from her home.

For Kovalchuk, now a cancer researcher based at the University of Lethbridge, Chernobyl remains a powerful symbol of why the world must remain vigilant of the risks involved in harnessing and using nuclear energy.

For cancer therapy, radiation is a two-sided coin. On one side, it’s an effective form of treatment, which has allowed countless patients to survive. On the other, radiation therapy can result in life-threatening secondary cancers such as lymphoma and leukemia. Kovalchuk’s research is aimed at addressing both sides of the coin—increasing survival rates while preventing secondary tumours.

Preliminary results suggest changes in the way chromosomes are packaged could contribute to

increased risk of certain cancers in people exposed to radiation in the workplace or through cancer therapy. Kovalchuk plans to build on this research in an attempt to understand more about how radiation induces secondary tumours in cancer patients and what can be done to protect the children of radiation-exposed parents from contracting cancer.

Kovalchuk is also studying whether certain agents derived from plants could be given to patients before they receive radiation therapy to improve their chances of survival and reduce the negative side-effects of radiation. This research brings her full circle to studies she conducted in the mid-1990s with her husband, fellow University of Lethbridge biological scientist Igor Kovalchuk. The couple, then working on their respective PhDs in Switzerland, examined the effects of radiation contamination on plants as a result of the Chernobyl nuclear accident.

Since arriving in Lethbridge in 2001, Igor has continued to focus on various aspects of plant biology while Olga has been increasingly involved in cancer-related research. For Olga, who earned a medical degree prior to becoming a full-

time researcher, this represents the marriage of two passions—health care and pure science. She believes that whatever is learned about preventing and treating human cancers could protect people should a Chernobyl-like tragedy ever strike again. “With all the talk lately of bioterrorism and dirty bombs, the world is a very shaky place,” says Kovalchuk. “We have to be extremely vigilant and always prepared to deal with the worst scenarios.”

Dr. Olga Kovalchuk is working to understand the impact of radiation on cancer patients and their descendants.

Alberta Cancer board and Foundation 2005/200612

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Cancer in Alberta

tests You Should takeBreast Cancer Screening in AlbertaOne of the most significant developments in the battle against breast cancer is the increased use of mammography for early detection. Since 1990 the Alberta Cancer Board’s Screen Test program has made it possible for women across the province to have a mammogram done in their community. Screen Test started in two fixed sites in Edmonton and Calgary, and has since fanned out across Alberta in mobile vans. Prior to Screen Test, only 17 per cent of Alberta women in their 60s and 27 per cent of women in their 50s were getting screened. Now, about 60 per cent of all women in Alberta are receiving the procedure.

This year, the Alberta Cancer Board launched the Alberta Breast Cancer Screening Programs. This initiative will bring all screening, whether conducted through the Alberta Cancer Board or by private radiologists, under one umbrella. The goal is to reduce deaths of Alberta women from breast cancer by at least 30 per cent.

For more information go to www.cancerboard.ab.ca/abcsp.

Alberta Cervical Cancer Screening ProgramCervical cancer is largely preventable, yet in Alberta 120-150 cases of cervical cancer are diagnosed each year, resulting in about 40 deaths. Human papillomavirus (HPV) infection is associated with virtually all cases of cervical cancer. Most cancers of the cervix can be prevented by regular Pap tests. Women 18-69 years old should have a Pap smear on a yearly basis.

In July 2006 Health Canada approved a vaccine which protects against the human papillomavirus that is responsible for most cases of cervical cancer. The vaccine will be sold by Merck Frosst Canada under the brand name Gardasil, and is approved for females between nine and 26 years of age to prevent cervical, vulvar and vaginal cancer, as well as precancerous legions and genital warts caused by HPV. Check with your doctor for more information.

Smoking Cessation has Immediate BenefitsMost smokers make an average of three or four quit attempts before succeeding as long-term non-smokers. Relapse is the rule rather than the exception and must be viewed as part of the process.

¸Within two days of quitting, the risk of heart attack decreases.

¸Within three months of quitting, circulation improves and lung function increases 30 per cent.

¸Within one year, the chance of smoking-related heart attack is cut in half.

¸Within 10 years, the chance of dying of lung cancer is cut in half.

¸Within 15 years, the chance of dying of heart attack is as low as for those who never smoked.

In 2003, 12,571 Albertans were

diagnosed with cancer and 5,192

people died from it.

In 2006 it is projected that close to

14,000 Albertans will be diagnosed

with cancer and more than 5,700

will die from the disease.

Cancer is responsible for 28 per

cent of all deaths and 40 per cent

of deaths between the ages of 35

and 64.

Approximately one in two

Albertans will develop cancer in

their lifetime and one in four will

die from cancer.

Leading cancers

% among total number of Albertans with cancer

% of deaths among total deaths from cancer

Prostate 17% 7%

Breast 15% 8%

Lung 13% 24%

Colorectal 12% 11%

What are the most common kinds of cancer for men and for women?The most common cancers causing death in men are colorectal, lung and prostate.

The most common cancers causing death for women are lung, breast and colorectal.

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Prevent cancers. Save lives. Eliminate suffering.

Fall of destiny

What happened was a major heart attack, 20 minutes of CPR administered by his wife, five shocks to the heart by the paramedics and three days in an induced coma to reduce stress on his heart. The cause of the heart attack? A rare anomaly of the experimental chemotherapy drug that, in another instance, had saved his life.

Smith was 39 years old with four young children when he was diagnosed with colorectal cancer. “Unless you have been through this, you can’t really understand what it is like,” he says. Smith felt angry, scared and alone.

Throughout the treatments, the recovery period and the setbacks, the hardest part for him was watching his children: “It is so hard for the ones standing on the sidelines,” he says. “It is very difficult for them to deal with this.”

Smith credits his recovery to the dogged efforts of his general practitioner in finding the cancer before it progressed substantially and to his aggressive chemotherapy. He also determined early on that “the cancer was not going to win.”

But Smith had no idea what a struggle it would be to stay the course.

Shortly after diagnosis he had surgery that revealed his stage three cancer had seeped into a couple of lymph nodes. Treatment with an experimental anti-metabolite chemotherapy drug was recommended. Anti-metabolite drugs stop cells from making and repairing DNA, a process cancer cells also need to grow and multiply. He “felt like hell” during the weeks he received the chemotherapy, but paradoxically felt better than he had in years on his off weeks from treatment when he managed to go for walks three times each day.

Smith has a clearer appreciation of what is important in life now. He feels a deep gratitude for every day and a determination to “leave something worthwhile behind.” A non-fiction writer by profession, he switched to fiction to express his experience with cancer and the resulting book, Fall of Destiny, is being released later this year.

For Smith, it’s a different life now, and even though the cancer has been in remission for more than five years, it remains a niggling threat. “It’s always there on my shoulders … but cancer is an infinitely survivable thing. Grit your teeth, stand up to it, don’t let it win.”

Rob Smith remembers carrying a piece of furniture up the stairs at home and feeling a bit dizzy. His next memory is of waking up in the hospital and wondering what happened.

Colorectal Cancer

Incidence 2003 Mortality 2003

883 Male 295 Male

669 Female 265 Female

1552 Total 560 Total

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Rob Smith with his seven-year-old daughter, Alexa.Alexa was six months old when her father was diagnosed with colorectal cancer.

Dr. Tony Fields has treated colorectal cancer patients for more than 25 years and sees progress at every turn.

“Even in patients of advanced diseases, we have more than doubled their life expectancy,” says Fields. “What this adds up to is that the risk of an individual dying of colorectal cancers has actually gone down a bit because they are less likely to get it at a given age, but more so, some combination of earlier detection and better treatment means the rate of decrease in deaths is moving faster than the decrease in risk.”

Fields says we also know more about risk factors and have made dramatic progress in diagnostic tools. Virtual colonoscopy is now possible, though limited by the availability of CT technology. And development of flexible sigmoidoscopy allows physicians to do more thorough exams in the medical clinic.

Surgical procedures have also improved enormously, especially for rectal cancers, says Fields, along with advances in post- and pre-surgical treatments.

Still, there is much to do, he says. “We still do less in promoting lifestyle change than we could; we do not know what proportion of patients with rectal cancer are getting the best modern surgical treatment; and we are painfully slow in clinical trials to define the role and benefits of the plethora of new and emerging drugs.”

Fields says we have also known for eight years that a comprehensive colorectal screening program where general practitioners order fecal occult blood testing for people over 50 every other year would save lives. “We have failed so far to implement an organized provincial screening program,” says Fields. “This is one of our top priorities for a new program.”

Advance of Success

Stepping up to Alberta’s Cancer Free Future 1�

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“often something that will benefit one disease may have an impact on other research. there are lots of ways of getting at the puzzle of cancer.” –Dr.Bill Johnston

Mary’s legacy

Establishing The Mary Johnston Professorship in Melanoma Research provided Dr. Bill Johnston with a measure of closure. For 21 years he and his wife, Mary, dealt with her recurring malignant melanoma; they discussed Mary’s wish to make a donation that would impact melanoma, a cancer with one of the fastest growing rates of incidence. The $1.1 million donation from Mary’s family and friends will provide funds to attract a leading melanoma researcher to Edmonton’s Cross Cancer Institute and leverage additional research grants for melanoma research. Johnston hopes the application of scientific medical research to bedside treatment of melanoma patients will have residual effects: “Often something that will benefit one

disease may have an impact on other research,” says Johnston. “There are lots of ways of getting at the puzzle of cancer.”

Above all, this tangible gift in memory of a much-loved wife, mother, friend and advocate is a positive tribute. “This is forward-looking—the naming, the memory, the dollars we have been able to give to the Alberta Cancer Foundation will hopefully make a difference in fighting cancer in the future.”

Prevent cancers. Save lives. Eliminate suffering.

Rates of melanoma skin cancer diagnosed in Canada are increasing each year.Protect yourself against skin cancer by wearing a hat, clothes that cover your arms and legs, and sunglasses that block both UVA and UVB rays. Use a broad spectrum sunscreen with SPF 15 or higher. Between 50 per cent and 80 per cent of skin damage occurs before the age of 18.

Artificial tanning in salons poses increased cancer risk to users.

Skin Cancer

Incidence 2003 Mortality 2003

193 Male 37 Male

175 Female 21 Female

368 Total 58 Total

be Sun Smart

Alberta Cancer board and Foundation 2005/20061�

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bill Johnston with granddaughter valerie,

who missed knowing her grandmother but will

benefit from her lasting legacy commitment to

addressing rising rates of malignant melanoma.

Stepping up to Alberta’s Cancer Free Future 1�

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research

targeting treatmentresearchers are taking a closer look at the factors that

turn normal cells into cancerous ones with the goal of

preventing cancer and treating it more effectively when

diagnosed.

Like so many, dr. Michael Hendzel has been touched by

cancer. More so than most,

his losses have helped shaped

his life, both personally and

professionally.

When he was 14, Hendzel lost his grandfather to liver cancer, and his interest in medicine began. In the late 1990s, just as Hendzel was wrapping up his post-doctoral research, his father died of prostate cancer. The loss helped cement his decision to accept a research position at the Cross Cancer Institute with a cross appointment as associate professor of oncology at the University of Alberta.

“When my grandfather died, I had this sense that I might be able to do something about it,” says Hendzel. “My father’s death got me thinking again about the importance of applying what I studied to immediate human problems.”

Hendzel’s field is epigenetics, the study of how gene-regulatory information—not expressed in DNA—is transmitted through generations of cells. At the heart of this field is the idea that genes have memory, that your ancestors’ lives and environmental influences can be imprinted on your genes. Hendzel estimates that epigenetic factors drive at least 50 per cent of the changes that turn normal cells into cancerous ones.

The aim of one of Hendzel’s projects is to improve the effectiveness of radiation therapy on cancer cells missed during surgery. In 10 to 20 per cent of cases, radiation treatment fails and the cancer returns. Treatment the second time is less likely to be effective and the cancer is more likely to spread—almost always fatally.

Hendzel and his research team measure DNA properties inside cancers and the surrounding normal tissues to try to predict how a patient will respond to radiation therapy. They investigate the way DNA strands are “packaged” or folded within a human cell. It’s thought that the more densely DNA is packaged, the more likely it is to be susceptible to radiation.

Understanding epigenetic change is important to developing potential cancer treatments because, unlike DNA mutations, epigenetic processes are reversible with non-toxic drugs now being developed. Hendzel’s team is testing these drugs over the course of the two-year research project.

“Traditionally, our approach to cancer treatment has been to administer non-specific toxic drugs to selectively kill cancer cells,” says Hendzel. “But, in fact, you also kill a whole bunch of other normal cells. This process is not about killing cells, but reversing them back to a normal state. So these therapies have the potential to be more easily tolerated by the patient and to stop the cancer.”

While Hendzel is currently working with human breast cancer cell lines in the lab, he is hopeful that learning more about the epigenetic signature of cells will pave the way for clinical trials. This could lead to breakthroughs in treating and preventing any cancer for which radiation therapy is now administered. For a scientist who has been touched so closely by cancer, that prospect is gratifying.

Dr. Michael Hendzel is researching how an individual’s response to cancer treatments is affected by genetic background.

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“things we could only have dreamed of before are now very near-term possibilities.” –Dr. Tony Fields

Milestone two

Two

Is a Cancer Free Future really possible? For Dr. Tony Fields, vice-president of medical affairs and community oncology, and one of the architects of the Alberta Cancer Board’s Cancer Free Future vision, the answer is an unequivocal yes.

“When I first started my career I was optimistic that by the end of my career most cancers would be preventable or curable,” says Fields. “I didn’t anticipate the difficult plateaus we would encounter that would make us feel like we were swimming through molasses.”

In the late 1970s optimism was buoyed by dramatic successes in treating childhood cancers and acute forms of leukemia, and it was thought these successes would transfer quickly to other cancers.

However, “these tumours were not about to bend their knees to the blunt instrument we had to deal with,” says Fields. “We believed our knowledge of lifestyle and environmental causes of cancer would be easily applied.” And

in the early days of ultrasound and CT scans, “We thought these advances would bring us ways for screening and early detection. What we found was really tough times with painfully slow progress. We had to go right back to the research laboratories to try to find answers.”

Today, we have vastly improved knowledge of cancer from the cellular through to the genetic and molecular levels, says Fields, and made new approaches to diagnoses and treatment. “Things we could only have dreamed of before are now very near-term possibilities.”

The century-old technology used at the beginning of his career wasn’t up to predicting the individual course of a cancer, says Fields. “We see a future where we say, ‘Your cancer has these characteristics, your body has those characteristics, therefore your treatment should be this,’ which is not the same as someone sitting next to you whose cancer would have been classified just the same as yours yesterday.”

Save lives

Applying Knowledge the Greatest Challenge“The wheels of discovery are spinning fast and the wheels of application are grinding slowly,” says Fields. “The more we can close the gaps between discovery and application, the faster we will see progress on the treatment side.

“With all of that, even with our relatively ad hoc and haphazard environment, we’re making real progress although not yet at a rate sufficient to meet our goals, which we deliberately set at a more aggressive level,” says Fields.

The greatest evidence of progress is in his patients, he says, using the example of an area he treats, colorectal cancer. “I have absolutely no doubt there are people around today who have avoided colorectal cancer or have survived colorectal cancer who would have been destined to die if we were still mired in our habits or technology of 20 years ago.”

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How do you cope with a diagnosis of cancer? Susan Leach’s response was to count her blessings and then get walking to fund cancer research.

each day Fully lived

Prevent cancers. Save lives. Eliminate suffering.

For Susan Leach, life couldn’t have been much sweeter. She had left her job as a chartered accountant to be a stay-at-home mom to her two daughters. She and her husband, John, had just moved into a new home. “On a number of occasions, John and I sat back and said, ‘How much better can life be?’” recalled Leach. “We both felt very blessed.”

Then, in October 2005, Leach felt a small lump in her breast. Her mind did not immediately race to thoughts of cancer. After all, she had turned 40 earlier that year and breast cancer is a disease that overwhelmingly afflicts women 50 or older. Leach had always been in exceptional health and carried none of the risk factors associated with breast cancer, such as obesity or a family history of the disease. But in December, her doctor told her she had breast cancer.

What goes through one’s mind at such a moment?

“Dying,” responds Leach. “That’s where you automatically go. You are terrified and you wonder, Will this be my path? Will I not be here to see my children graduate from school, to attend their marriages, to play with my grandchildren? But my husband and I decided ‘That will not be our story.’”

Three days before Christmas, Leach underwent a lumpectomy (a partial mastectomy). Because of the holidays, the pathology results would be slow

in coming. The family had planned a 10-day Caribbean cruise starting on December 29. They decided to go ahead with it. “We could have all sat here and stared at each other as we waited for more information or we could go on the cruise,” says Leach. “We chose the latter and I’m glad we did. It provided a lot of opportunities for focusing on something else.”

When they returned to Calgary Leach was given the good news that the cancer had not spread to her lymph nodes and the prognosis for a full and lasting recovery looked good. She had every reason to believe she would be among the two out of three women who are diagnosed with breast cancer and who do not die of the disease.

Leach began chemotherapy treatment in January, followed by radiation therapy. She was also put on a year-long treatment of herceptin, an antibody that attacks the cancer-enhancing protein HER2, as well as tamoxifen, a drug that blocks the ability of estrogen to feed cancer growth. Together, these treatments are meant to kill any cancer missed by the original surgery and to reduce the risk of tumour cells returning at a later date. The side-effects from her treatments were relatively modest. She suffered minor nausea from the chemotherapy as well as the inevitable—and, to her, quite devastating—hair loss. Radiation therapy sometimes left her fatigued. But the biggest impact has been on the way she looks at life.

“I’ve always been the kind of person who was very busy, who constantly went from one thing to the next,” says Leach. “I’m really bad at taking time for myself. Now, I know that taking care of me and my physical health has to be a priority.”

Even in the midst of her cancer treatments, Leach decided to start training for the 2006 Weekend to End Breast Cancer event, held in both Calgary and Edmonton. In part, Leach simply wanted something healthy to focus on as she recovered. She also felt a sense of gratitude, knowing that the $50,000 a year it costs for herceptin treatment*—for her and more than 100 other Alberta women—was raised in large part at the Alberta Cancer Foundation’s 2005 inaugural Weekend to End Breast Cancer walk in Calgary. She’s doing her part to give back, too—Leach is one of the biggest single fundraisers for the Calgary event, with $20,000 pledged to her two-day, 60-kilometre walk.

But most of all, Leach hopes that the research funded through the annual walk will help finally crack the puzzle that is breast cancer so that her children and grandchildren might be spared. “I wouldn’t ever wish what I’ve gone through on my daughters,” says Leach. “I’m very hopeful that by the time they are in their 20s, we’ll know a lot more and may even have a way to prevent this disease. Wouldn’t that be great?”

Alberta Cancer board and Foundation 2005/200620

* Herceptin is now funded in Alberta to treat early-stage breast cancer.

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Breast Cancer

Incidence 2003 Mortality 2003

13 Male 3 Male

1794 Female 420 Female

1807 Total 423 Total

Stepping up to Alberta’s Cancer Free Future 21

Weekend to End Breast CancerThe 2005 Weekend to End Breast Cancer in Calgary was the single largest breast cancer fundraiser ever held in Alberta, raising $7.1 million. The event left a legacy of healing, enabling the Alberta Cancer Foundation to invest $5 million in breast cancer research and programs to benefit patients and families throughout Alberta.

• $3 million launched the Alberta Breast Cancer Research Initiative, funding 12 new breast cancer research projects in Calgary, Edmonton and Lethbridge. This was approximately 10 times the Alberta Cancer Board funding allocated for breast cancer research in previous years.

• $1 million funded a compassionate program that provided more than 180 Alberta women with herceptin while formal evaluation of the new drug was being completed.

• $1 million purchased state-of-the-art equipment to enhance patient programs:

- A fully equipped mobile van to make breast cancer screening more accessible to women in over 100 rural communities;

- A dedicated ultrasound unit for the new breast cancer surgery suite at the Cross Cancer Institute;

- A genetic analyzer that will further breast cancer diagnosis and research in the translational labs at the Tom Baker Cancer Centre.

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Prevent cancers. Save lives. Eliminate suffering.

Margo Schulte McKinnon loves a party. So to celebrate the end of 18 months of treatment for incurable follicular lymphoma, she threw a great one—and charged admission.

“I did not picture this as primarily a fundraiser,” says McKinnon, “but as an opportunity to celebrate, a chance to relax, to dress up and laugh a bit.”

That first party, dubbed the “Snowball Event,” was a laugh and more. It raised $3,000 for new wigs at the Cross Cancer Institute. “It was more devastating than I thought it would be to lose my hair,” says McKinnon. Faced with a selection of “a number of curly, grey wigs,” McKinnon at first despaired; when she rooted out a new long, red-haired wig, she “felt so much better.” Thanks to her party proceeds, women now have an additional 30 stylish choices. Subsequent parties have raised funds for blanket warmers and flat-screen TVs for the day care area at the Cross Cancer Institute.

McKinnon chairs the upcoming fourth annual Snowball Event but says, “Though I still have my finger in everything, I’m delegating more.” A team of volunteers now works the event, and the guest list goes well beyond McKinnon’s immediate family and friends.

There is no known cure for her lymphoma, but McKinnon feels well on the road to recovery. The aggressive chemo treatments she received, followed by annual antibody-based drug therapy, have given her life back, literally, she says. “The reality is that this is a painful, painful journey of self-awakening and awareness. If you can come out the other side—it’s magic. You realize the only limitations are the ones you put on yourself.”

The next Snowball Event is November 16, 2006, at Dante’s Bistro in Edmonton. For tickets go to www.thesnowball.ca.

Keeping Her Head upA young mother marks the end of her cancer treatments by throwing a party with a cause.

Special Events—Special People!Each year hundreds of volunteers and participants in communities throughout the province generously contribute their time and energy to raise funds on behalf of the Alberta Cancer Foundation. In 2005/2006 these special people raised over $4 million in support of world-class cancer care for all Albertans.

For a listing of the 2005/2006 community fundraising events, see page 46.

Alberta Cancer board and Foundation 2005/200622

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Margo Schulte McKinnon’s ordeal with her incurable lymphoma has taught her to cherish every moment.

“if you can come out the other side—it’s

magic. You realize the only limitations are

the ones you put on yourself.”

Stepping up to Alberta’s Cancer Free Future 23

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When Irving Kipnes was diagnosed with prostate cancer, he and his wife, Dianne, were shocked. “We both felt fit and had always lived a healthy lifestyle,” says Dianne. “We just could not believe this.” Irving approached cancer the way he met most challenges, by becoming as informed as possible. “I became an expert in this cancer, even to the point of suggesting what type of treatment I should receive to my doctor. I definitely did not want surgery and was determined to avoid it.”

When his wife was diagnosed with cervical cancer three years later, she took a different approach. “We each dealt with our cancer diagnosis very differently,” says Dianne. “I determined immediately that I would have the surgery. This was followed by radiation and chemotherapy.”

The dark days of treatment, worry and fear are behind them now, replaced by clarity for what is important in their lives, and by vulnerability. “I feel totally healed and well now, but am very much aware of where I have been,” says Dianne.

Their journeys were the impetus for a remarkable gift—the endowment of the Kipnes Research Chair in Radiopharmaceutical Sciences at the Cross Cancer Institute. The $5 million

donation, the largest ever received by the Alberta Cancer Foundation, will provide funds to attract a top scientist to focus on developing new indicators to find, diagnose and monitor cancer cells. This research will translate into improvements in both diagnosis and treatment and will allow more effective monitoring of cancer therapy in progress. The research will be applicable to multiple types of cancers.

According to Irving, this donation is specific to cancer research as opposed to broader scientific research: “We expect this fund will attract one of the world’s best researchers to the CCI’s Centre for Biological Imaging and Adaptive Radiotherapy,” improving on an already remarkable diagnostic and treatment suite of biological imaging tools.

Apart from the desire to support cancer research, the Kipneses hope their Alberta Cancer Foundation donation sets an example. “There is no better feeling in the world than to give to this cause,” Dianne says. “We knew we could not help everyone with cancer, but this is important research that can make an immediate difference.”

From their HeartsIrving and Dianne Kipnes were inspired by personal experience to support research targeted on reducing the incidence and the mortality rate of cancer.

Prevent cancers. Save lives. Eliminate suffering.

Prostate Cancer

Incidence 2003 Mortality 2003

2151 340

Ovarian Cancer

Incidence 2003 Mortality 2003

177 109

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Irving and Dianne Kipnes are enjoying life’s blessings and good health after individual bouts with cancer.

Dr. Sandy McEwan, director of the Cross Cancer Institute’s Oncological Imaging Unit, calls the $5 million donation from Dianne and Irving Kipnes “manna from heaven.” Their funds will attract an internationally renowned radiophar-maceutical scientist to Alberta who will “move our research in molecular imaging forward by five to 10 years,” says McEwan.

The Alberta Cancer Board’s Positron Emission Tomography (PET) Program, located within the world’s first Centre

for Biological Imaging and Adaptive Radiotherapy at the Cross Cancer Insti-tute, images abnormalities of function caused by disease. The most common type of PET scan uses a radioactive sugar to assess the metabolic rate of a cancer—the more aggressive the cancer, the higher the metabolic rate and the more sugar it uses. However, there are also other biological and metabolic abnormalities associated with cancer that can be detected by PET, which may lead to improved patient care. Conducting fundamental research

to develop new radioactive tracers for these applications will be one of the key responsibilities of the team led by the new Chair.

Development and validation of new markers to assess how rapidly cancer cells are reproducing, how well a patient will metabolize chemotherapy drugs and what mechanisms control cell death will help oncologists assess and treat cancer more effectively—and that will help improve patient outcomes.

“there is no better feeling in the

world than to give to this cause.”

Fundamental Research Will Improve Cancer Treatment

Stepping up to Alberta’s Cancer Free Future 2�

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Searching for the best Solutiondr. Katia tonkin is

assessing estrogen

levels in women with

metastacized breast cancer

to determine the value of

hormone therapy versus

chemotherapy in their

individual cases.

research

Tonkin, a senior medical oncologist at Edmonton’s Cross Cancer Institute as well as an associate professor with the University of Alberta, works extensively on clinical trials.

In one of her latest trials, funded through the Alberta Breast Cancer Research Initiative, Tonkin will follow 100 patients whose cancer has become metastatic—that is, at some point after the initial diagnosis and treatment, the cancer has returned, this time spreading to another part of the body such as the liver, the lung or, most commonly, the bone.

Typically, such patients have from a few months to a few years to live.

Tonkin and her colleagues are using a relatively new and innovative type of positron emission tomography (PET) scanning that looks at estrogen levels. Traditionally, PET scans involve injecting a small amount of radioactive glucose (sugar) into a vein and then using a scanner to make detailed, computerized pictures of areas inside the body where the glucose is used. Because cancer cells often use more glucose than normal cells, the pictures can be used to find cancer cells in the body.

But many cancers are also fed by estrogen and can be treated with hormone therapy, which is considered far less invasive than chemotherapy and avoids side-effects such as hair loss. When breast cancer is first diagnosed, the cancers are tested to see if they are hormone-positive and therefore likely to respond to hormone therapy.

The problem, says Tonkin, is that hormone therapy is not always effective once a tumour has metastacized. “When you treat them with hormones, only some of the cancer will respond. So let’s say they have a few lumps in their lungs and some in their liver. You might find the ones in the lung shrink very nicely, but the ones in the liver don’t.”

dr. Katia tonkin is constantly impressed with the altruistic

nature of many breast cancer patients and their willingness

to participate in studies while very ill.

Dr. Katia Tonkin works extensively on clinical trials at the Cross Cancer Institute.

A significant impact on the number of cancer cases that will occur in Alberta will come from two aspects:Size Our population is continually growing and is projected to increase more than 30 per cent by 2025. Even if the risk of developing cancer does not change, the increase in population means there will be more cancer cases in the province.

Age Alberta’s large generation of ‘baby boomers’ are entering an age where cancer becomes a health concern. An aging population will have a direct impact on the number of cancer cases in this province.

Alberta Cancer board and Foundation 2005/20062�

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Rese

arch

In addition to a traditional glucose-based PET scan, the patients in Tonkin’s study will be examined using a new type of PET scan which measures the sites of breast cancer that take up estrogen. This technology, under development for the past five years, is available in Alberta only on an experimental basis. The point is to measure specific estrogen levels of each individual cancer to make sure that they really would respond to hormone therapy—and to do that before any treatment begins.

Tonkin’s expectation is that, in a significant number of cases, patients whose original cancer tested hormone-positive will learn through this new PET scan that the metasticized cancer is not, in fact, being fed by estrogen. In that event, they will not be given hormone therapy and will instead likely be placed on chemotherapy. The bottom line? “Because we normally wait two or three months to evaluate if a treatment is working,” observes Tonkin, “we could be wasting that time doing something that’s ineffective.” That would be especially tragic for patients who have precious little time to lose.

¸ Tobacco is the single largest preventable cause of cancer. Choose to be a non- smoker and avoid second-hand smoke. Chewing tobacco and snuff are not safe alternatives to smoking.

¸ Eat five to 10 servings of vegetables and fruit daily. Fresh, frozen, canned and dried vegetables and fruit are all good for you. One serving is about the size of the palm of your hand, or approximately ½ cup.

¸ Maintain a healthy body weight with a healthy diet.

¸ Add physical activity to your daily routine. Forty-five minutes of vigorous physical activity, five or more days of the week, is optimum.

¸ Practise sun safety—cover up, use sunscreen SPF 15 or higher and seek shade. There is no such thing as a healthy tan and tanning salons are not safe alternatives.

¸ If you are a woman 50-69 years of age, have a screening mammogram at least once every two years. If you are 40-49 years of age, consult your doctor about the opportunity to access a screening mammogram.

¸ If you are a woman over 18, have a regular Pap test, which can prevent almost all cervical cancers by finding cell changes early enough for a woman to be treated and cured.

¸ See your doctor and dentist regularly for check-ups and right away if you notice any change in your normal state of health. One-third of all cancers could be cured if detected early and treated adequately, so pay attention to changes in your health.

¸ Avoid exposure to hazardous materials and environmental carcinogens.

A young mother diagnosed with cancer begins a long journey of doctor’s visits and treatment appointments. Who cares for her children while she is away and recovering? How does she cover the extra cost of child care? The Alberta Cancer Foundation’s Patient Financial Assistance Program was established to provide short-term grants to patients and their families who experience financial difficulties as a result of their treatment. The assistance could go toward travel and accommodation costs associated with accessing cancer treatment or to help with loss of income when a patient is unable to work.

“I was not even aware of the great need for extra support for some cancer patients before I heard about

this program,” says donor Bibianne Robitaille, but when she heard about the program administered by Alberta Cancer Board social workers, she saw a way to make a tangible contribution. Robitaille and her husband, Willard, have directed their annual Alberta Cancer Foundation donation to the financial assistance program and to cancer research for six years. In this way, they help those with cancer today, and work toward eliminating cancer tomorrow. “Research will make the difference,” says Robitaille. “By the time our grandchildren grow up, we will have made real progress on fighting cancer.”

For more information on the Patient Financial Assistance Program go to albertacancer.ca.

Prevention stepsto reduce your risk of cancer and other chronic diseases

Making a difference today

What is cancer?Cancer describes more than 200 diseases that can affect any part of the body. Their common factor is the rapid creation of abnormal cells which can spread to other parts of the body, a process called metastasis.

Can cancer be prevented?Fifty per cent of cancers are preventable and cancer prevention is our best opportunity to reduce cancer deaths. Research has shown that we can reduce the incidence of cancer by practising a healthy lifestyle.

Stepping up to Alberta’s Cancer Free Future 2�

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research

Computer-designing Cancer treatmentdr. Jack tuszynski is using computational biophysics

to design drugs that will combat cancerous cells but

minimally impact healthy ones.

The computer looks unassuming

enough. But inside dr. Jack tuszynski’s desktop machine

runs a processor that could

hold a key to the f ight

against cancer.

As the Allard Research Chair in Oncology, Tuszynski heads a team at work building “designer drugs” able to kill tumours and eventually lead to cancer cures.

“My hope is that the tangible effects are not that far away,” says Tuszynski, also a physics professor at the University of Alberta. “Once we have all the proper equipment in place, our work could save years of research time, millions of dollars and would take the guesswork out of finding the proper drugs to treat cancer.”

Simply put, the goal of Tuszynski’s computational biophysics work is to create the perfect drugs that would target cancerous cells while reducing side-effects to the healthy cells. For example, he and researchers from Texas have already developed a new generation of chemotherapy drugs called Taxol, a class that interacts with certain proteins in cells to stop cell division and eventually the spread of cancer. Taxol drugs

currently stop cell division in both healthy and cancerous cells; the new class of these drugs being designed by Tuszynski and his colleagues will mainly affect cancerous cells.

During his first sabbatical in Europe Tuszynski toured a number of labs and had time to reflect on his career. It was then he decided to focus his expertise in biological physics on fighting such diseases as cancer. To achieve success in this new but promising field of biological modelling, Tuszynski drew on his physics background to help create a computer software program that scans all proteins against all available chemical compounds to find the perfect match. Ten years later, the intricate program he worked on can tell scientists exactly how well the protein might bind to the drug.

“This is based on the principle of fitting like a lock and key,” says Tuszynski. “Once you find that match, you can move on to determining the actual dosage, formulation or best way to administer it. But before that point, you need what we call rational drug design. Otherwise the way of trying to figure out the best drugs would be called irrational, serendipity or an educated guess.”

Tuszynski hopes that within two years his research group will be able to boast that it is the only one in the world capable of running the complete cycle—starting at the computational

model through to clinical trials. “That’s my dream and if we do that, we could achieve the end goal of killing tumours in a patient-specific manner; this is not the case today.”

Collaborating with top researchers at the Cross Cancer Institute and in Texas and China will help speed that goal along, but the lack of needed equipment closer to home is slowing the team down. Currently, they have access to 100 processors, most scattered at individual workstations. To be able to calculate millions of possible targets against millions of possible drug compounds, at least 1,000 processors are needed. “When you think about the cost and years, likely decades, we could save in the long run the cost is worth it,” he says. “I work in a building where I walk past people every day who are very sick and it is impossible not to be affected by that. To think that we could be so close to changing people’s lives in such a positive way is very exciting.”

Dr. Jack Tuszynski was appointed Allard Research Chair in Oncology in October 2005. The Allard Research Chair is supported by an initial $2 million donation from the Allard Foundation to the Alberta Cancer Foundation. The $3 million Chair is supported by the Alberta Cancer Foundation’s Research Endowment Fund.

Dr. Jack Tuszynski is the new Allard Research Chair in Oncology at the Cross Cancer Institute. He applies his physics expertise to developing cancer drugs.

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“if, as a society, we are not able to remove suffering, there is really something wrong.” –Dr. Jean Michel-Turc

Milestone three

Three

eliminate Suffering

How can anyone eliminate suffering? It seems like an impossible goal, but according to Dr. Jean Michel-Turc, president and CEO of the Alberta Cancer Board, the relief of suffering is a fundamental human right.

“If, as a society, we are not able to remove suffering, there is really something wrong,” says Turc. “We know how to do it. We have the tools to do it. There really is no excuse.”

Suffering stems from fear, pain and worry. It has psychological, physiological and intellectual dimensions. And for each, there are avenues of relief. “If you are able to control the suffering part, as an individual you have more tools to deal with the rest of the disease,” says Turc.

Inevitably, for now, there are those who will die of their cancer. Still, says Turc, we need to do everything possible to ensure their days are still filled with life. We need to support them in a way that ensures “they are at the end of the road because of the natural course, not because they don’t want to fight anymore.

“In this day and age, suffering is not acceptable. We need to apply what we know consistently. Yes, some patients will have a very high level of pain, but we need to deal with it.”

Stepping up to Alberta’s Cancer Free Future 2�

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Finding voiceLife-threatening disease was not part of Calgarian Yvonne Merchant’s retirement plan. But in 2002, four months after retiring as an insurance agent, Merchant, 62, was diagnosed with a rare and incurable CUP (or cancer with an unknown primary origin) glandular cancer, found in only two to five per cent of the population.

Merchant and her husband, Peter, were just finalizing plans to head to Australia to celebrate life as retirees when she experienced persistent coughing and swelling in her neck. Multiple visits to the doctor didn’t identify a cause, but upon her return from abroad, tests revealed a cancerous lymph node.

At first, chemotherapy kept the cancer in check, but after two years she experienced more swelling and developed cancer in her ovaries. A hysterectomy and more rounds of chemo were followed

a year later with more swelling and yet more chemotherapy.

Merchant tolerated the chemotherapy and physically fared well. The emotional effect of dealing with incurable cancer was another story.

“You hear the word ‘cancer’ but what it really means and how it will impact you, you just don’t know,” says Merchant. She was referred to Dr. Barry Bultz, director of the Department of Psychosocial Resources at the Tom Baker Cancer Centre, and a clinical psychologist whose pioneering work helps address the psychological, emotional, spiritual and quality-of-life issues after diagnosis.

She spent her entire first visit crying.

“One of the first things he said to me was ‘You don’t have control over the

cancer, but you have control over how you live with it,’” says Merchant. “It’s so true. You really have no other choice when you have an incurable disease. It is not going to get better.”

Facing the reality of Merchant’s illness has been particularly hard for her three grown children. “It’s a lot of processing for them because they have never seen me ill,” she says. “The only time I was ever in the hospital is when I had each of them.”

Individual and family counselling with Bultz has helped them cope with the reality of cancer. And through group therapy, they’ve built a network of close friends. Yoga and meditation are now part of life as is an annual “de-stressing” vacation in Mexico.

“The biggest thing I’ve learned through this experience is to maintain hope,” says Merchant. She faces more chemo and drugs to control the pain, but is determined to live each day fully. Most people diagnosed with her type of cancer die within a year. She has lived four.

“Who knows why I am still here?” she says. “Yes, I’m going back into chemo, but I’m doing okay. If that is what I have to do to survive, then so be it.”

Yvonne Merchant discovered that treating her cancer was more than just physical. She sought support for dealing with the emotions of living with incurable cancer.

Prevent cancers. Save lives. Eliminate suffering.

Enbridge Research Chair in Psychosocial OncologyThe Enbridge Research Chair in Psychosocial Oncology is one of the first of its kind in

North America. The $3 million Chair at the University of Calgary is co-funded by the

Alberta Cancer Foundation and the Canadian Cancer Society, Alberta/N.W.T. Division.

Alberta Cancer Foundation funding includes a $1.2 million donation from Enbridge

Inc. This gift, the largest charitable donation ever made by Enbridge, was a centennial

gift to all Albertans facing cancer. It is now part of an Alberta Cancer Foundation

endowment fund established through a 1996 Enbridge-sponsored campaign to create a

stable and secure source of funding for cancer research. The Conquering Cancer Research

Endowment Fund is now in excess of $48 million.

Alberta Cancer board and Foundation 2005/200630

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Yvonne Merchant determined the best way to work through her anger and fear after her cancer diagnosis was to talk about it. She received support through the psychosocial oncology program at the Tom Baker Cancer Centre.

“the biggest thing i’ve learned

through this experience is to

maintain hope.”

Unknown Primary Cancer

Incidence 2003 Mortality 2003

153 Male 144 Male

158 Female 144 Female

311 Total 288 Total

Stepping up to Alberta’s Cancer Free Future 31

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Managing Paindr. neil Hagen is dedicated to eliminating pain

and suffering in cancer patients to provide them with

the best quality of life possible.

research

dr. neil Hagen understood his

life’s calling from the moment

he began his first rotation as

a neurology resident at the

renowned Mayo Clinic. “I was

placed on the cancer ward,”

recalls Hagen, “and I knew

right then I wanted to be a

neurological oncologist.”

A subsequent two-year fellowship in neuro-oncology and cancer pain management at a New York City hospital reinforced Hagen’s desire to help patients deal with the horrific pain that often accompanies cancer, especially in its final stages. “It’s really quite tough to be silent in the presence of the kind of suffering one encounters in advanced cancer,” says the Edmonton-born Hagen. “But I soon realized there’s a lot that can be done for these patients, pain control being one of the most important.”

Many cancer patients experience pain as a result of the cancer spreading to other parts of the body, most commonly to the bones—what’s known as metastatic cancer. There are examples of metastatic cancer being cured, but it’s extremely rare; most patients facing such a diagnosis have between a few months and a few years to live. But, as Hagen says, “Even if a person has limited time, they can still have dignity and a sense of intactness as a human being.”

Pain management is key to give these patients the best quality of life possible in the time they have left. Even when pain is well-managed, Hagen says, the majority of patients will suffer so-called “breakthrough pain”—brief flashes of severe distress that, on average, are as

bad as it is going to get within three minutes and usually last no more than 30 minutes if untreated. For someone whose cancer has spread to the bones, breakthrough pain usually occurs when they try to move their limbs—for example, to stand up or attempt to take a bath.

Currently, breakthrough pain is treated with narcotics such as morphine and methadone in the form of a pill. But it takes between 15 and 30 minutes for the pills to deliver relief. “That means it’s just beginning to work at the point the flare-up pain is ending,” says Hagen. “So what’s used around the world for this common pain problem is often quite inadequate.”

Hagen and his colleagues asked themselves a basic question: How can we get a drug we know will work into a patient’s bloodstream quickly and in a convenient and safe manner? They already knew that methadone, which is fat-soluble, delivers pain relief within three minutes when given intravenously (by comparison, morphine, which dissolves in water, takes 15 minutes to be effective, even when delivered by an IV). They also knew that the small, juicy blood vessels underneath the tongue absorbed fat-soluble methadone far better than water-soluble morphine. So why not

Dr. Neil Hagen is investigating ways to deliver pain-killing drugs to cancer patients to limit the impacts of breakthrough pain.

Alberta Cancer board and Foundation 2005/200632

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Rese

arch

Healing through ArtThe Arts in Medicine program encourages patients to express themselves through paint-ing, sculpture, music, photography, fibre arts and soapstone carving. In 2006, Dr. Marilyn Hundleby, a clinical psychologist and director of the Arts in Medicine program, and cancer survivor Sherry Abbott co-authored Cancer and the Art of Healing, a book showcasing the cre-ations and personal discoveries of more than 300 Arts in Medicine participants.

The book was published through a grant from the Alberta Cancer Foundation and is available for purchase at albertacancer.ca.

“i vividly remember what a struggle it was to

begin to paint—but i didn’t have the strength

or capacity to pull my thoughts together in

words. i could barely speak. tears flooded me all

the time. today while i was painting the world

around me stopped, and i was in a stress-free

environment.”– Arts in Medicine participant

explore the potential for providing quick relief by putting small doses of liquid morphine under the tongue?

A small pilot project proved the concept sound, and preliminary results suggest cancer patients are receiving full relief in as little as five minutes. Starting in the summer of 2006, Hagen will oversee a study of up to 60 patients in Calgary, Edmonton and London, Ontario. If all goes well, he hopes to proceed to a full-fledged clinical trial in less than three years.

The procedure being tested could dramatically improve the lives of cancer patients. “If there was a way to manage breakthrough pain pre-emptively by putting a few drops of liquid under your tongue five minutes before you get up or go to move, it could revolutionize a person’s quality of life.”

For Hagen, the basic lesson is the one he’s been learning since he stepped on to the cancer ward at the Mayo Clinic. “The dark truth,” he says, “is that a large percentage of people who get cancer are going to die from it. But no one with cancer should suffer.”

Psychosocial oncology Care in the Community Cancer networkThirty-five to 45 per cent of people diagnosed with cancer experience significant distress at some point in their cancer journey. On-site psychosocial services are available at the Cross Cancer Institute in Edmonton and the Tom Baker Cancer Centre in Calgary; patients and families across the province have access to psychosocial support closer to home through our community cancer network.

For more information on psychosocial support go to www.cancerboard.ab.ca/maco/initiatives_psychosocial.htm.

Compassion and CareIn 2005, an estimated 5,000 Albertans died of cancer. Palliative care support ensures that, even in dying, patients can love, be loved, live.

“It’s hard to die,” says Deb Gitzel, a palliative care resource nurse. “It is just such a tough journey.” But so much can be done to help.

Gitzel clocks more than 2,000 kilometres per month in her area around Stettler, visiting patients in their homes, hospitals or continuing care facilities at the request of their caregivers. She helps families understand what support is available and helps dying patients feel at ease. “A lot of my work is symptom management,” she says. “Making sure patients have adequate medication to deal with their pain and discomfort means they can do the things they want to do, for as long as possible—even though they are dying.”

The Hospice Palliative Care Network works with regional health authorities to improve access to palliative care throughout rural Alberta. To learn more, visit www.cancerboard.ab.ca/maco.

Stepping up to Alberta’s Cancer Free Future 33

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Looking at him now, you could not tell that Brendan was ever ill. He is bright, cheerful, articulate and athletic, with a zest for life like any 10-year-old’s. But when he accompanies his parents on their annual fundraising events, he’s a symbol of success in the fight against cancer.

Craig and Carolyn O’Callaghan were expecting their second child when two-year-old Brendan became terribly ill. He was admitted to the University of Alberta Hospital (now the Stollery Children’s Hospital) and diagnosed with a rare B-cell acute lymphoblastic leukemia (ALL). The aggressiveness of Brendan’s cancer forced an equally aggressive response by his oncological team: for eight months he was isolated from the general public and underwent rounds of chemotherapy. Reacting with fear to the pain, little Brendan simply stopped talking for the entire period of treatment.

When they finally returned home, Brendan’s build-up of months of rage was released in screaming fits. The O’Callaghans credit the Cross

Cancer Institute with helping them reclaim some normality in their lives. “The counsellors and support givers understand all the other aspects of the disease,” says Carolyn. “I knew I could call them anytime I needed—it made a huge difference.”

Brendan is now cured. The O’Callaghans say they can never repay the caregivers who saw them through this, but they have certainly tried. In their home town of Wetaskiwin and surrounding area they are known for the annual Short Cut to the Cure, which has raised $340,000

for the Alberta Cancer Foundation in the past five years. They also speak at close to 40 events annually throughout the region.

“We tell everyone their dollars are making a difference,” says Craig. “The money we raise attracts other seed money and research grants.”

“For us, it’s personal,” says Craig. “Before this, we didn’t know much about cancer. Now we know how it affects lives, and we want to help beat it.”

resolved to Make an impact

“For us, it’s personal.

before this, we didn’t

know much about cancer.

now we know how it

affects lives, and we

want to help beat it.”

–Craig O’Callaghan

Leukemia

Incidence 2003 Mortality 2003

242 Male 93 Male

150 Female 98 Female

392 Total 191 Total

Brendan O’Callaghan has been cancer free for close to eight years, but his family will never forget the day they learned their two-year-old son had leukemia. Their journey through Brendan’s diagnosis, illness and treatment has left the family with one goal—to ensure a cancer free future becomes reality.

Prevent cancers. Save lives. Eliminate suffering.

Alberta Cancer board and Foundation 2005/20063�

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Brendan O’Callaghan is a picture of health today and an example of great progress in

dealing with childhood leukemias.

Stepping up to Alberta’s Cancer Free Future 3�

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The team behind these individuals includes the Alberta Cancer Foundation and more than 100,000 Albertans who generously donate each year for cancer research, prevention, treatment and care throughout the province. In the 2005/2006 fiscal year, total revenue including lottery proceeds and investment income exceeded $30 million, more than double the amount of the previous year. Full financials for the 2005/2006 year are available on our website at albertacancer.ca.

These individuals turned “I wish there was something I could do” into more knowledge through research; into prevention initiatives and screening services like a new mobile breast screening van; into more accurate diagnostic and treatment tools such as the positron emission tomography (PET) scanner imaging unit; and into a helping hand when needed most from the Patient Financial Assistance Fund.

Our donors made personal donations both large and small. And they put ingenuity, muscle and humour behind countless fundraising walks, runs, head shaves, silent auctions, bake sales, car washes and golf tournaments. They bought lottery tickets, responded to our mail campaigns and remembered us through estate gifts.

The most common thread for each of our donors is a personal connection with cancer. Many are cancer survivors themselves. Many give to honour the memory of someone lost to cancer. For others, raising money for the Alberta Cancer Foundation is a meaningful way of saying “I care” for someone they know who has cancer, or “I care enough to invest in ensuring cancer has no place in my future or that of my children.”

The Alberta Cancer Board has set an ambitious vision of a Cancer Free Future. The Alberta Cancer Foundation and all Albertans who support it have a critical role in helping to make that vision a reality.

Thank you.

Pattie Culver Chair, Alberta Cancer Foundation

Linda Mickelson Chief Executive Officer, Alberta Cancer Foundation

demonstrated Care Stepping up to a Cancer Free Future—together

More than 13,000 Albertans

will be diagnosed with cancer

this year. These individuals

and their families will meet

and be supported throughout

their cancer experience by an

outstanding team of health-

care professionals—including

researchers, doctors, nurses,

pharmacists, social workers

and therapists.

Alberta Cancer board and Foundation 2005/20063�

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thank you*

Thank you to all our donors and volunteers who will help us make a cancer free future reality. The following have donated $1,000 or more over their giving history, and have made gifts of $500 or more between April 1, 2005, and March 31, 2006.

Honoured benefactors ($5,000,000 plus)

The Dianne & Irving Kipnes Foundation

distinguished benefactors ($1,000,000 – $4,999,999)

Canadian Cancer SocietyEnbridge Inc.D.W.C. Johnston

Patrons ($100,000 – $499,999)

Medical Research Fund (at the Calgary Foundation)CIBCDon D. & Valerie CopelandEngineered Air—Resman Community ServicesDon & Kim GrayHelen & Peter HaasLehigh InlandNeil & Edith MacGillivrayFrank Sojonky & Carla Cumming Sojonky

Partners ($50,000 – $99,999)

AnonymousARC Resources Ltd.The Bear Children’s FundDevonian PropertiesEnCana Cares FoundationEnCana CorporationNeil Harvie FamilyLook Homes Inc. Building Cures for KidsAlex & Jean McDougaldGeoff & Hugh OslerUnited Way Alberta Capital Region Donor Directed ProgramUnited Way of Calgary and Area

builders ($25,000 - $49,999)

324 Holdings Ltd.Anonymous (2)ATCOATCO GroupHarold & Linda BanisterCIBC World Markets Children’s Miracle Foundation

Civic Service Union 52Digital Communications—Rogers WirelessJames & Magda DykstraGilbert Laustsen Jung Associates Ltd.Haywood Securities Inc.Katherine LaschowskiAllan P. MarkinPricewaterhouseCoopersRBC FoundationJim RichlStarPoint Energy Ltd.R.H. (Dick) & Nancy Wilson

Sponsors ($10,000 – $24,999)

Anonymous (5)ARC Financial CorporationDonald ArchibaldAssociazione Trevisani NelmondoGerry & Beverly BerkholdBlake, Cassels & Graydon LLPAndrew Boland and Lynn ElstonBosoms or Bust TeamRuth & Dorothy BowerM. Scott BrattBull Moose Capital Ltd.Burlington ResourcesCam Clark FordVincent Chahley and Patty IrwinJohn & Karin ChambersCIBC World MarketsFred ColesVijay & Suzanne DomingoECL Group of Companies Ltd.Edmonton JournalGlen EllisGolden Gate Lions ClubRobert & Cathy GrundlegerDixie & Tom HagermanFrank HallHFKS Architects Ltd.Shawn & Rhonda HendersonPeter & Deanne HenryRalph K. HoleBonnie & Daryl Howard

Integrated Production ServicesDarrell Jones & Alison JonesRudy & Anne KlawonKobayashi Partners LimitedBarry LeeThe Lukey FamilyFlorence McGinnisBruce MiyashitaMotorolaNexen Inc.Paramount Resources Ltd.Pentastar Energy Services Ltd.Petrofund Corp.Progress Energy Ltd.RBC Dominion Securities Inc.Riley’s Reproduction & Printing Ltd.SamsungSandlewood Developments Ltd.sanofi aventisSaville GroupSentry Select Capital Corp.Wayne Sharp and FamilySteve & Carolyn SoulesSouthern-Asselin FamilyJohn M. StewartJohn ThiessenTELUS Community ConnectionsMichael & Renae TimsTop DrawTransCanada CorporationUniglobe Geo TravelDeborah Yedlin & Martin Molyneaux

Contributors ($5,000 – $9,999)

Airways Truck Rentals & LeasingAlberta Blue CrossAlberta Building Trades Council Charitable FoundationDon & Fran AndrewsAnonymous (4)ArgusAstraZeneca Canada Inc.Axiss Marketing Inc.Jim Baird

Our donors are recognized in this publication and on our donor walls with written permission.

Stepping up to Alberta’s Cancer Free Future 3�

Every Contribution CountsThe Alberta Cancer Foundation was established in 1984 to support and enhance the treatment facilities and provincial cancer care programs of the Alberta Cancer Board. The money you give supports research discoveries that will improve treatments and save lives. Your donations also directly support patient care and help our caregivers provide both information and comfort to patients and their families. And, keeping Albertans informed about the role they can play in a healthy future will pay tremendous dividends.

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Barbecues GaloreMary BarrBeaver Drilling Ltd.Bob BentleyBarry & Deborah BentzDonald & Rita Bosch & FamilyMr. & Mrs. James F. Burns Sr. Family Fund at The Calgary FoundationBurstall Winger LLPCanadian Natural Resources LimitedCanadian Oil Sands TrustRaymond & Philomena ChanThe Cretan Society of CalgaryDouglas & Margaret CummingCummings Andrews MacKayHerman & Elly De JonghPeter & Helen DyckEagles Nest Cateringedatanetworks Inc.Edmonton Strathcona Lions ClubEecol Electric Inc.Herbert & Jeanette EllisExecutive Women International —Calgary ChapterGeorge C. Field Endowment Fund at the Edmonton Community FoundationFirstEnergy Capital Corp.Fort Road Bingo AssociationKevin FosterPat & Joe FreedmanGienow Building Products LtdGreat HobbiesGriffiths McBurney & PartnersElmer & Penny Harbridge Fund at the Calgary FoundationHigh Point Resources Inc.Hitfar ConceptsHole’s Greenhouse and GardensEdward HolzapfelHSE Integrated Ltd.James & Nancy HuttonIBM Employees’ Charitable FundIGL Canada Western Ltd.Integrated Production ServicesKinsmen Club of BrooksMervin & Edna KruegerDr. Allan LeboldusNorma MacLean & FamilyMacLeod DixonKeith & Kathryn MacPhailMammoth Productions Inc.Mancal CorporationMaunders McNeil Foundation Inc.McCarthy TetraultMitchell & Kimberly MolloyDonna MulhollandMichael MyshakNabors Drilling LimitedNokiaNorthrock Resources Ltd.Rene PhalempinPhoenix Technology Income Fund

Pirie FoundationJohn W. PorterChris, Holly & Chloe PotterPrint Works Ltd.Provident Energy TrustPTI Group Inc.QualicoJohn & Sandy Read Family Fund at The Calgary FoundationReal Resources Inc.Sanjel CorporationSchendel MechanicalLeon & Michell SeifermanGreg Royer/Serval Services LimitedHarvey & Audrey ShawSobeys WestSony EricssonSoroptimist International of EdmontonSterling CraneTerracore Specialty Drilling Ltd. Thunder Energy Inc.Tidal Energy Marketing Inc.Tirecraft Auto Centers Ltd.WAM Development GroupC. James WelchDoug WiensRon WighamDavid & Penny WilsonWRD Borger Construction Ltd.

Supporters ($2,500 – $4,999)

Acclaim Energy TrustAdams & MacGregor Consulting Ltd.Advantage Oil & Gas LtdAlberta TrussAlberta Tubular Products Ltd.Alliance Drilling Fluids Ltd.AltaGas Services Inc.Anonymous (15)Avalon Junior High SchoolWillem & Catharina BaasLeslie E. BissettDouglas BlairBooster JuiceBonnyville Bingo AssociationBrahma Compression Ltd.Brinkhaus JewellersIan & Darlene BruceCalgary Co-operative Association LimitedCalgary Sewfest Ltd.Campbell Park Bingo AssociationCanadian Progress Club of St. AlbertCanadian Western BankCaron Transportation SystemsCathedral Energy Services Ltd.CCS Income TrustCDL Systems Ltd.Champion TechnologiesJoan CharbonneauYvette ClaveauNoel ClelandReginald & Jean Coroy

J. Russel CukrPatricia CulverDawson Wallace Construction Ltd.DeloitteDick Cook SchulliDivine Hardwood FlooringDynetek Industries Ltd.Edmonton Public Teachers’ Local 37 Charity Trust FundEmans Smith Andersen Engineering Ltd.The Enerplus GroupThe Focus Corporation Ltd.Dr. T. Chen FongFontaine Pipeline Ltd.Fort Chicago Energy Partners L.P.Foundation of Hope Employees’ Foundation Bank of Montreal Group of CompaniesB. Ross GilesWilf GobertGrandin Bingo PalaceDon & Betty Ann GravesWilliam W. HaleHard Wok Buffet, SaskatoonHarry HoleSissy & (Scobey) HartleyRichard & Lois HaskayneJerome & Lorraine HastingsRon & Jacqueline HayterThomas & Linda HeathcottThoma HessHoffmann La Roche LimitedHokanson Capital Inc.J. Leonard HolmanHygaard Fine Foods Ltd.Industrial Machine Inc.Innovative Chemical Technologies Canada Ltd.Inside Education - 20th AnniversaryInter Pipeline FundInvestors GroupJasper Avenue Pizza Ltd.JOG CapitalKensington Bingo CentreMartin KingKnights of Columbus Holy Family Council 4957KPMGEdward & Marjorie KulyLakeland & District Bingo Association of Cold Lake, ABLandrex Developers Inc.Friends of Jill LarawayLear Real Estate Ltd.Leduc Rapid Bingo Assn.Heather & Thomas LesterGwenyth LewingtonLiliana’s Boutique & DecorDorothy LitkeLockerbie & Hole Contracting LimitedLuscar Ltd.Mac MacKenzie FamilyMasters Energy IncMatco Investments Ltd.McElhanney Land Survey Ltd.

Thank You

Alberta Cancer board and Foundation 2005/20063�

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Gordon & Dorothy McMillanLinda MickelsonMLC GroupMr. LubeNavitas Energy Group Ltd.Kevin Peterson & Sheila O’BrienParkallen SchoolParlee McLawsBrian & Michelle PawlPembina Pipeline CorporationThe Principals & Staff of Peters & Co.Philips Medical Systems CanadaDavid & Anne PhillipsPioneer Press Ltd.Plains Marketing Canada, L.P.Polartek 2000 Ltd.Premier Integrated Technologies Ltd.PrimeWest EnergySusan L. PritchardBarb ProdorJack & Bonnie RawlyckSharon R. ReesResolute Energy Inc.Conchita ReyesFloyd & Nancy ReynoldsRiley Resources Inc.George SamoilSamson Canada ResourcesSavanna Energy Services Corp.SCF PartnersScotiabankDaryl K. SeamanGraeme & Luciana SivertsonSpiral of Life Cancer Support—Smith, ABSpruce Grove Bingo CentreWarren & Teresa StarkSteeplejack IndustrialStreamline Construction Co. Ltd.Louisa TangTerasen Pipelines Inc.Tirion Properties Ltd.The Dobbin GroupThe RoadhouseThermo King Western Ltd.Timing Energy Inc.Trail Building Supplies Ltd.Jack & Dawn ThrasherTristone Capital Inc.Patricia TrottierUltraline Services Corp.United CycleWarrant Officers’ & Sergeants’ Mess 4 Wing Cold LakeDr. Sharon WatanabeJane Weller & Dale MageeWest Edmonton KegBen & Fran WhitworthRobert M. WilkinsonWomen of the Moose Chapter 853Woodridge Lincoln MercuryW.Y. Svrcek Engineering Ltd.David Yager

Zargon Oil & Gas Ltd.

Friends ($1,000 – $2,499)

783 (Calgary) Wing RCAFA784 (Wing) AFAC652717 Alberta Ltd.Abria Financial GroupAccrete Energy Inc.Acklands-Grainger Inc.AcrodexMadam Justice Darlene Acton & Donald M. ScottActual MechanicalAGF Funds Inc.AGRA Foundations LimitedAgristar Inc.Ainsworth Financial Services Ltd.Airdrie Windshield & Glass Ltd.Al Amira Temple DancersAlberta Blue Cross Staff AssociationAlberta Computer Cable Inc.Alberta Mining Corporation LimitedAlberta Oil ToolAlberta Oil Tool Employee Goodwill FundAlberta Rose InsuranceAlberta Traffic Supply Ltd.All Weather WindowsJon AllenRae & Carol AllenAloette of Edmonton SouthAlstom TransportGeorge AndersonJ.C. (Jack) AndersonAnderson Well Servicing (1986) Ltd.Anglo Canadian MotorsAnonymous (33)Gino & Silvana AntonelloAON Financial Benefits GroupArrow Welding & Industrial Suppliers Inc.ATCO Electric—ECHO FoundationJames P.G. AtkinsonAvison Young Commercial Real EstateBaker Oil ToolsDorothy BanserJim & Carole BarkerDoug & Laurel BaronGreg & Kim BarrettGarth & Jo Ann BarrickB. Margaret BawdenBBQ Acres Caterers Ltd.Beaubien Glover Maskell EngineeringIan & Robin BeddisPierre BelandBer-Mac Electrical InstrumentationReginald & Glenys BerrySusan BertolinBob & Shirley BexsonB.G.E. Service & Supply Ltd.Thomas BieschkeLynda BinderBiomira Inc.Ruth Birchall

Dale & Jane BirdsellB-Line Contracting/A Division of Kozicky Construction Ltd.Mr. & Mrs. John BlackstockBlueGrouse Seismic SolutionsBlumont CapitalBMO Nesbitt Burns—The Seed TeamSteven BodonScott BoltonMarc BombenonHugh BorglandBouchard Well Service Ltd.Marion & Donald BoucherDorothy (Peggy) BoukJacob BouwmeesterBower Dental CentreJanine Boyer-Kwong Fund at The Calgary FoundationTodd BradleyTracy BradleyDoreen M. BrayNorm BraybrookSimon & Meg BregazziSharon BroadbentBronco Mud Inc.Alan BrowneIrene BrowneBRT Construction Services Ltd.Richard & Heather BryantRon & Phyllis BryantBumper Development Corporation Ltd.David & Marlene BurnettBurnet Duckworth and Palmer LLPBruce F. BurnyeatBrent ButtonKen CairnsThe Calgary Crescendo Choir SocietyCalgary Flames FoundationCalgary Southridge Lions ClubShea Nerland CalnanNancy & Bruce CalvinJohn & Elizabeth CameronPatricia CameronDavid CampbellGarth & Marguerite CampbellGary CampbellCanadian Rocky Mountain ResortsCanadian Tire—Pacific PlaceCanetic Resources Inc.Cargill FoodsCarl Bachand ConsultingDon & Betty CarlsonCarma Developers Ltd.Castledowns Bingo Staff & FriendsCastledowns Lions ClubDrs. Carol & David CassCE Franklin Ltd.Centron Construction GroupCESSCO Fabrication & Engineering Ltd.Ajay ChadhaNathan & May ChanChapau Rentals Ltd.

Stepping up to Alberta’s Cancer Free Future 3�

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Mark ChapelskiMarc CharronBrian ChatwinAllan ChengChocolate and ChucklesCitadel Community Book SaleCKB Construction ServicesStuart ClarkEd ClarkeClear Vista SchoolDan & Nancy ClementClub Bingo HallChristine ColesDon CollisonContact Exploration Inc.Contour Earthmoving Ltd.Co-operators Life Insurance Co.Elsie CooperMarshall CopithorneHelen CorcoranLorna CorcoranCore Lab Pro Technics DivisionCorus EntertainmentKathryn Wyatt CottinghamHeather & Joe CouillardCrescent Point Energy TrustCrossbow Machine Corp.Crosstown Heating & Ventilating Ltd.CT Performance Inc.Mike CurriePatrick & Dora DanielDart Compressor ServicesJim W. DavidsonGynell DawsonRick DawsonD&B Lumber & Supplies Ltd.Defiant Energy CorporationResi Del PiccoloDelta Kappa Epsilon Men’s Fraternity (Delta Phi Chapter)Derrick Exhibit & Trade Show ServicesGary & Janice DietrichDIRTT Environmental SolutionsDouble R Building Products Ltd.James & Marjorie DownieDuncan & CraigGrant Dunlop & Erika NorheimDynaline IndustriesEmma & Gifford EdmondsEdmonton Area Council One SocietyEdmonton KubotaEd’s Oilfield ConsultingEECOL ElectricSan ElgertElk Point Oilmens AssociationG. & P.G. ElliottE.N.E.B.A. HallEnterra Energy Corp.Epsilon Chemicals Ltd.Eton West Construction Inc.Exp. Peterson InstrumentsBrian & Gail Faulkner

Earl FawcettBrad FedoraNachman FeldmanBetty Brook FerdynWalter & Ellie FettLarry & Jan FichtnerDr. & Mrs. Tony FieldsBruce FiellFilipino Senior Citizens AssociationFillmore Construction Management Inc.George FinkFinning (Canada)Archie & Madeline FischerCW Fischer & J.A. CuthbertsonGlen FischerFogolar Furlan di CalgaryTom FossFranklin Templeton Investments Corp.Troy FranksFraser Milner Casgrain LLPFraternal Order of Eagles Ladies Auxiliary #2098Mike FrenchFriends at Bally’sRenee-GadesMatilda GallantDonna GalvinHelen GardinerGelding Welding Ltd.Gem Cabinets Ltd.Getronics Canada Inc.getservd.comRon & Myrna GhitterGiant Grosmont Petroleums Ltd.B. Ross GilesWilliam & Pauline GirgulisGlenluce Resources Ltd.James GlennWilfred & Margaret GobertKarman GoochNorma GordonDouglas & Joanne GossG.P. Coskey PC - Chartered AccountantG.P. Friendship Centre BingoAlf & Connie GrahnGarry & Brenda GrayGrizzly Resources Ltd.Gummow’s Construction Ltd.Walter & Ann HaesselPatricia HagenHallmark Tubulars Ltd.Doris HamiltonHamilton Hall Soles/Ray & Berndtson Inc.Janice HammondTom & Char HandRonald & Judy HansmaVernon & Leona HartwellHawthorn Interiors Ltd.Joan Healey - ArtistHeart Kitchen & BathJack HeartwellDave Hellard

Pat HethringtonArt HibbardHigh Mountain Feed Distributors Ltd.High Park School, Stony PlainThomas & Vivian HollandJohn & Jane HolmlundCheryl & Andrew HowdenHub International TOS LimitedJohn & Evelyn HudakBrad & Michelle HummelEverett Hunt & Isabel HuntMary Ellen HuntHurley’s Meat Distributors Ltd.Imperial Oil FoundationIndependent Order of Foresters Branch New Horizons #1747Integrity Land Inc.International Brotherhood of Boilermakers Local 146IPEXIPSCO Inc.Jack & Margaret Charlesworth FoundationJayman For Life TeamJ.D.A. Ventures Ltd.JED Oil Inc.Gloria JichitaJilly’s Home & LifestyleCliff & Ruth JohnsonAndrew & Suzy JudsonRichard & Sue KanegawaKayden Industries Inc.Robert & Hilda KeirMr. George Kesteven & Ms. Nancy HudakColin KinleyDenise & Kyle KitagawaKiwanis Club of Calgary ChinookKnights of Columbus —St. Joseph Assembly #05Gerald J. KnollGerald S. KnollJean KnoppWilliam & Marguerite KohutKomex International Ltd.Andy KramchynskiKrawford Construction Inc.Anne KrigovskyKubota Canada Ltd.William LaceyLafarge Canada Inc.Lamb’s Trucking Ltd.Ken & Janet LandsiedelMichael LangRichard & Betty LaversBarbara LeahWendy A. LeaneyLaura LeeLouise & Jack LeeForrest LesterRaymond W. and Mary E. LewisLexus of EdmontonMiles & Karen LichLiquor Stores Limited Partnership

Thank You

Alberta Cancer board and Foundation 2005/2006�0

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Lloyd Sadd Insurance Brokers Ltd.Andy & Sue LockhartDouglas A. LockieBev Longstaff & Joe StruckLookout Enterprises Ltd.Tom & Dora LovePaul LovellRobert LovellFrank & Agnes LovsinKenneth E. LudlowLux Windows & Glass Ltd.Tom LygoRonald & Marion MacGarvaDennis & Lois MaciborskyWallace & Margery MacInnesMackenzie Financial CorporationMaclab EnterprisesCathy L. MacLeodGary MadsenTrevor MaguireDavid & Donna MagusManulife FinancialEstella MarchmentMarshall’s Furniture Galleries Ltd.Chris MarshmanMartin Newby Consulting Ltd.Pam, Jenn & Jeff MatsumiyaF.R. & J.W. MatthewsMawer Investment ManagementDavid McDermidDr. Brad McDonald P.C.Terry & Sherry McDonoughLilian McEwenW. Clifford McGinnisMary McGurranMcKenzie Lake Community AssociationCatherine D. McKercherMcKessonMarilyn McLachlanRoderick & Mona McLennanBrenda McNabbHeath & Donna McNeilRobert McQuayDebra-Lori McRaeMedicine Hat Cancer Centre—StaffMeier Auction & LiquidationMelcor Developments Ltd.Jeannette MelnykMadeleine MercierMerdeka Energy Ltd.Meyers Norris Penny LLPBob MichaleskiJ. Garnett & Xenia MillardDennis G. MillerScott & Michelle MillerMiller ThomsonJames MitchellDoug & Judy MohsMolson Canada Alberta RegionPeter MonkRon MorissetteDr. Shane Mortimer

Mountain Aire Realty Ltd.Mud Master Drilling Fluid Services Ltd.Susan MunnBarry MunroNeil & Susan MurphyMyrnam Crooked Shooters Hockey ClubNagel Tours Ltd.NAM Management GroupNational BankLidija NesgaardJim NobleNor-Alta Energy CorporationNorth Peace Investments Ltd.NR-Tec Ltd.Optima Manufacturing Inc.John OslerGeorge OswaldBarbara PalmerConstantin PapadimitropoulosAnn PardonPark Paving Ltd.Parkway Bingo HallPat’s Off-Road Transport Ltd.Corinne I. PaulPeak Energy Services TrustPenfabco Ltd.Katie PennerRobert G. PetersPetro Canada - Edmonton RefineryCameron PlewesTed PoppittPositive Pressure Testing 2003 Inc.Precision HyundaiWilliam & May Ellen PringleProcter & Gamble Inc.Brian Prokop & Kathryn NunnProline Pipe Equipment Inc.Prudential Steel Ltd.Ptarmigan Charitable FoundationGillian & Ernie PyeQualico Developments West Ltd.S. Pickard & C. QuilliamRadiology Consultants AssociatedRaylin Manufacturers & Distributors Ltd.Raywalt ConstructionRCG Group—VancouverR & D Trailer Rentals Ltd.Kenneth & Barbara ReedFrank J. ReillyLee RichardsonRigstar CommunicationsRitchie FamilyRitchie Bros. AuctioneersRivard Design Inc.Robert Tegler TrustDave and Drue RobinsonNan RobinsonSandy J. RobinsonRobnic Holdings Ltd.Maxine Rodgers & Howard KnappDr. Adrien RougetOrder of the Royal Purple Barrhead No. 132

Gilles & Shawna RoyerV. V. (Val) Rundans, P. Eng.Irene RutherfordSalvi HomesSamson Canada Ltd.ScepterSchell Equipment Ltd.Elaine SchieweJanice SchultzJan SeamanSentinel Self StorageShamrock Valley Enterprises Ltd.Shane Homes Ltd.Derek SharpElizabeth ShawJR ShawSheila SideySinai Engineering CorporationSinclair DentalGary & Georgi-Anna SizelandSteven & Cindy SlupskyDerek Small and Barb GoslingGordon & Fay SmithJim & Cynthia SmithSoby GirlsMargaret SouthernSpiker EquipmentRon StaderSt. Ambrose Elementary & Junior High SchoolM.A. StanfieldStantecStantec Consulting Group Ltd.Patricia StewartDave & Jennifer StobyStonefield Development ConsultantsSt. Paul Westend BingoLloyd & Geri StrainStrategic Construction Solutions Inc.Jack SteenStuart Olson Construction Ltd.Superior Propane Inc.Sureway Construction Management Ltd.Sarah SussmanBetty SwitzerTaiga Forest ProductsT.A.K. Oilfield Sales & Service Ltd.Byron & Angela TamFlorence TamDylan & Elaine TaylorTD Commercial BankingTechna-West EngineeringBruce & Sharon TelfordThe Brick Warehouse CorporationThe Design Group Staffing Services Inc.Gary & Marg ThompsonTIC CanadaTolko Industries Ltd.Wayne & Marion TooleTooth Replacement Dental Specialty CentreTorske Klubben of EdmontonBill TowsleyTransAlta Corporation

Stepping up to Alberta’s Cancer Free Future �1

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Transat A.T. Inc.Travelodge CanadaBrian & Diane TraversEdward & Joyce TrewinTrico Homes Inc.Triwell Oilfield ConstructionBill & Marie TrofimukMarguerite J. TrusslerTTG Systems IncorporatedTulissi Construction Ltd.UBS Commodities Canada Ltd.UFCW Social Fund—Local 1118United Way of Lethbridge and South Western AlbertaLinda VanDijkLynda VankoughnettVast Resources Ltd.VECO Canada Ltd.Vector Electric and ControlsVernon Barford Junior High SchoolVeteran Resources Inc.Paul VineyVinterra Properties Ltd.Vision Theatre Players GuildGilbert VooysGordon VooysGlenda WaddinghamMark & Bernice WalkerWalkers Grocery Ltd.Robert & Jean WallWalton International GroupLinda P. WardDan & Molly WaresKaren L. Warren-MacNeillDonald H. Watkins, Q.C.Andrew & Crystal WatsonLynn WebsterConrad & Esther WedinJenny WeingardtGordon WeisenburgerWestern Securities LimitedWestern Sterling Trucks Ltd.Wetaskiwin Bingo StationHarry & Bette WheelerDuane E. WikantWilliam de Haas Prof. Corp.Robert A. WilsonRobert & Joanne WilsonThe Ron Winkelaar FamilyWMJ Metals Ltd.Wolseley Canada Inc.Gerry & Elaine WoodDan & Carolyn WoodruffThe Wordie FamilyWorldlink Transportation Ltd.X-Act Technologies Ltd.James YiYork Realty Inc.Graeme YoungPolly YuKim & Gloria YurchakLeib & Bettina Zeisler

Friends (500 – $999)

Fred & Carol AbbottAccess Plumbing & Heating Ltd.ACT/UCT Calgary North ClubAcumen Capital Finance Partners LimitedDavid G. AdamBlair AlbersGerald AlexanderAllwest Commercial FurnishingsStefan & Irene AnderhubAlbina AndersonPike & Barbara AndersonRon & Marion AndersonAnonymous (21)Anran Enterprises Ltd.ATCO Gas Community Service Fund (ECSF)Aurora Night ClubAzim A. Bharmal Professional CorporationBetty Jean BaldwinLionel BandcroftBankers & Traders Insurance Brokers Inc.Bennett Jones VercherePatricia Ann BernardDavid W. BettsBig Top Tent RentalsGwen BlackstockGerda R. BloemraadJan & Lorna BloemraadBowness High SchoolRonald B. BoychukRichard & Deborah BoydDouglas, Shannon, Hunter, Theron BoyerBrandt TractorVivian BrenneisBruce Deacon & Helen BrisbinMike & Jacquie BroadfootBrosseau & AssociatesGary BrowneMarian V. BuschCalgary Celtic Supporters ClubGreg & Carol CameronGordon & Elizabeth CarswellCavalier Land Ltd.Peter & Florence CheungChristensen & McLean Roofing Co.Circle K International Volunteer Club - U of ABrian & Joanne Clark & FamilyKatherine ClementNeil CockburnGordon & Maxine ColeConocoPhillips Canada Ltd.Control Flow Hydraulics Ltd.James (Bert) CooperLaurie CoopersmithCormode & Dickson Construction (1983) Ltd.William & Mary CornsJeff & Andrea CoswanPatricia CraigMarion CrawfordEnid CrockettCrystal Glass

Custom Vacuum Services Ltd.Patricia D’ArcyJames DavidsonDonald & Linda DaviesDeFord Contracting Inc.Johannes & Agatha de GoeijJanet R. DenhamerTerry & Norma DewhurstAllen DiedeBob DinningGlen & Deborah DisleyDuke Energy Field Services CanadaRitchie & Kathleen DyeKenneth & Audrey EdwardsEeson & Woolstencroft LLPHarold S. EikelandElite TaekwondoP. Davis & Deborah ElliottCatherine EllisEnersul Inc.EPCORErnest Troescher InspectionsErnst & YoungPatricia FarleyFather Kenneth Kearns SchoolF & D Scene Changes Ltd.John & Peggy FedchukFero CorporationMichael & Peggy FieldDennis & Donna FlanaganShawn & Bonnie GallagherLloyd William GardinerCharles & Deborah GargusJohn GillardG.L.M. Tanks & Equipment Ltd.Colin GlasscoTanis GoskiLillian GoudieClements GrandelAustin G. & Evelyn A. HadlandKeith & Betty HansenThomas & Gertrude HawkwoodW. E. Ted HeaverMaurice & Shirley HenricksonMary M. HetheringtonRuth HicksPhilip & Maria HodgeMr. & Mrs. J.H. HolmesBlaine HookMilton & Barbara HorricksJoan T. HorteAdolph HuebnerJoni HughesJanet L. HutchisonJoyce & Curtis HvingelbyJohn & Miranda IftodyJackson FarmsJajan Holdings Ltd.James Sinclair Management Ltd.Jarman MazdaLloyd & Alice JohnstonFaye Julien

Thank You

Alberta Cancer board and Foundation 2005/2006�2

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Lyle KabanukKehoe EquipmentJanice & David KentNick & Mary KlementovichJohn & Audrey KolesarRoy KubicaJosephine Nikiforuk LeBlancBill LevisL L & S Holdings Ltd. (John Niedermaier)Dr. Donald LloydEdward LucaGerald & Peggy LucasMalcolm & Patricia LundBeth & Tom MacInnisBert MadillFraser MalcolmPhilip McAvoyMcCaw Truck & Equipment Ltd.Donald W. and Myrna McDonaldStanley C. McDonald & Betty Hurley McDonaldJill & Graham McLennanGerard MeagherHarry & Martha MillerJohn & Maggie MitchellMiriam Mitchell-BanksWalter MontgomeryDonald J. MorrisonMoxie’s Classic GrillNorberg & Margaret MrazekMullen Transportation Inc.NAL Resources Management LimitedRonald Neuman & Karen KvillJ.E. Ted NewallCarla NicolaNorthlands ParkOakcreek Golf & Turf Inc.Clifton D. O’BrienJohn O’CallaghanO’Connor Associates Environmental Inc.Allan & Frances OlsonEsther OndrackFranz OppenheimOrder of Royal Purple Lodge 32Leo OrnestParkallen KnittersDouglas PengellyPerry Oilfield Services Ltd.Alver & Arlene PersonJim PescottPetrin Mechanical Ltd.James PheaseyLaura PoirierAlan & Marian PriceWilliam & Maggie PringleProfessional Medical AssociatesDorothy RauschRBC Financial Group—Employee Volunteers Grants ProgramJohn & Claire ReadNorma J. ReichertMargaret RichardsKen & Carol Rispler

Willard & Bibianne RobitailleArthur W. RowntreeRobert & Jennie SayerSchering Canada Inc.May SchulteHerman & Alice SchwiegerSusan ScottByron J. SeamanDonald & Eleanor SeamanNicholas SellmerToshimi & William SemboRussell & Mildred ShepherdShiny SolutionsShores, Belzil Jardine, Barristers & SolicitorsJim SinclairRuth & Don SmillieFrank J. SmithJ.C. SmithNeil & Karen SmithSam SmithM.H. Snyders BlokSouth Edmonton Lions ClubSouth Rock Ltd.Standard General Inc.Drs. Adalei & Elout StarreveldMori & Sheilah StelmaschukBrenda & Derril StephensonKen StephensonCaron and Michael StewartDouglas StolleryStrathearn Heights Ltd.Craig & Deborah StylesSuncor Energy FoundationSupreme Steel Ltd.John & Jessie SveinsonBud & Melita SwartzTalisman Energy Inc.Lynda & Barry TempleThe Horses OfftrackMike & Julia TkachukEthel TuckerJim TurnerUBS Securities Canada Inc.United Way of Fort McMurray Workplace CampaignsWilhelm UnrauRon & Joan ValensDr. Peter M. & Mrs. Mary VennerVermilion Energy TrustJean WatersMarilyn & Gord WeberCharles & Audrey WhitesellWigham ResourcesOliver & Gwendoline WilsonWinstar Resources Ltd.Women of the Moose Wetaskiwin Chapter 559Louise I. WordenWrent-a-WreckH.N. (Bud) & Mary YatesElizabeth & Bill Yuill

bequests

We acknowledge the following visionary donors who chose to include the Alberta Cancer Foundation in their estate plans. Their thoughtfulness provides a legacy of hope.

Saran AhluwaliaHarriet V. ButcherCarol CrossZane FeldmanSam GoldsmithBarbara GrahamCatharine C. JamiesonTheresa JarmanClarice Mary JonesSharon LangGeorge MalashukChristine Marshall MartinMargaret Elizabeth MorantViolet Lillian NortheyRobert William OttoIngeborg Anna Martha PagetStanley RobinsWilliam John SaundersJack SherrattLouise SilkstoneFred SkidniukAlbert StickelEleanor Willerton

in tributeWe are honoured to acknowledge the following individuals remembered through gifts totalling $500 or more between April 1, 2005, and March 31, 2006.

in MemoryBrian AherneGlenn AlexanderMary AmbroseDon AndrewsPhyllis Andrietz (nee Frankiw)Anonymous(2)Roberta M. ArcherHendrik (Hank) ArnoldussenWillem & Catharina BaasDeanna Darlene BagstadDr. Gordon BainJoyce BalaneckiGarth BarrickShary BarschelRick BasarabaHerman BauwensPauline Dianne BeauchampJohn Macdonald BeddomeLouise BelikVel Ben LaminBonnie BennettEvelyn “Scotty” BentleyJohn BertleffMary Ellen BeuginRobert BlackstockJan Bloemraad Sr.

Stepping up to Alberta’s Cancer Free Future �3

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Randall BochaneskyShirley Jean BodnerMary Lynn BogartMichael BoneEvelyn BornMyrna BoscherFern Lorell June BouwmeesterBetty Ruth BrackenburyDavid BradshawJohn A. Bray (Jack)Elizabeth BreezeDoris BrennanVivian BrenneisLorraine BrockelsbyJoyce BruntDianne E. BuskoAnthony CairoGerald CameronJohn CameronPatricia CameronJoseph CampArchie CampbellDion CarrierC.W. CarryBeatrice ChalifouxKen CharbonneauThomas (Tim) CholowskiJerry ClarkeThomas (Tom) Clement Sr.Kevin CookGeraldine CorcoranJean CoroyDavid Alan CotterellPatricia CoutneyChristine CoxIrene CrissEnid CrockettMirella CrudoDuane DallynHerb DavenportDorothy Margaret DavisonH.J. (Jock) Dawe FamilyHenry De HaanRobert DeatherageGertrude DeeringResi Del PiccoloDouglas DelahuntPatty DelhezDiane DemersMarcella Diana Den HartogLeta Mae DePratuAntoine DescehnesPaolo Di CesareAlan William DickenRobert Gordon DittmerJames Maxwell Mallett DobsonAlbert DominiukAlistair DonaldRoland Dore’Jean DumontDonald & Sally DunlopHelen S. Dyck

Mervyn EastmanEmma EdmondsAudrey EdwardsNedima EllisFreda EmmelkampJack EvansJean EversArthur FedynaVerna FellowsGeorge FenAnna Teresa FinotGrant Leslie FisherTracey Renee FlaggElizabeth A. FlaglerWayne Thomas FochM.”Deane” FossenSuszanne FoyNadie FrankiwPaul GagnonLarry GardeskiLloyd William GardinerSusan Anne GardnerJared AnthonyJoyce GaulinAdelbert Otto GerlachDenise GibsonDennis GiebelhausBernie GiesbrechtElise GillHarry GirgulisJeff GoinDamon Jay GoskiPatricia Anne GraceJennifer “Jen” GregoryArtur GrugerLucille GuenetteCharles HackenschmidtEric HagermanGloria HaightMark HalwaGary J. HansonDonna Ruth HarperAdam HartfelderLorraine HastingsYoshiki HataMilred M. HawkinsPatricia HealyPeter Michael HedleyPete HeideLoyola HelmigAllin HendersonDon HillCindy HoGeorge Gerald HoffosPatricia HogaboamJim HoldenThe honourable Lois E. Hole Ralph K. Hole, Jr.Ho HongAnne E.M. HopeDarren R. HowardHeather Huet

Ryan HuskinsDr. Michael J. HutchisonGenah HysRonald (Ron) Neil JacksonA. Clare JohnsonMary I. JohnstonPaul Francis JohnstonGlyn JonesWinstan Morris JonesGeorge Arthur JordanTrevor JulienLyle KabanukMaleksultan Sarudin Habib KarimEdna A. KaryElizabeth (Betty) KennyBarbara KeownNadine KibblewhiteLaurie KitchenEula KlaskAlice KlippensteinDonna KnocklebyBert KnoppVerna Madge KobewkaElizabeth KobieMable KordybanMillie KossowanSheila Joan KowalchukGordon KozensLoretta KoziakMary Veronica KrigovskyMary Elizabeth KrigovskyWalter KunickiJohn KutneyJosephine (Josie Gartke) LabatiukDonald Clarence LaBergeLillian LamashBrian LaytonRobert John LaytonClaudette LeboldusJean Louis LeeMary TsuiDavid Tinsang Lee YingKathleen LemayAl (Chub) LinklaterDouglas A. LockieAlison LookStephen Wayne LouieSiu Lung LuiBarbara LukeyAndy LuthinT. Peter LuziDavid LygoAlexander (Sandy) MacDonaldHelen MacLeanJudith-Anne Marie MacMillanRichard (Jeff) MacMillanGeorge MacPheeFraser MalcolmDr. Yale MalkinJulienne MarchakAntonio MarghellaKaren Elaine Marshall

direct donations: Phone: 1-866-412-4222 online: www.cancerboard.ab.ca/foundation

Mail: Alberta Cancer Foundation, 1220, 10405 Jasper Ave, Edmonton, AB T5J 3N4. Charitable donation number: 11878 0477 RR0001

Alberta Cancer board and Foundation 2005/2006��

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Herbert (Scotty) MartinPoul MathiesenDarryl MatsumiyaEdna McCallumDr. William Duncan McCubbinJoanne McEwenGarry McIlvrideEvelyn Rose McKellarMargaret Jean McLachlanMarilyn Jean McMurrayFloyd MehalcheonGarry MellumDaniel MercierWesley C. MeynMargaret M. MicallefDavid Staveley MiddletonJune MiddletonBrian David MillarMay MillarMichael MillenaarDon MillerRoss MitchellGary MittelstadtPam MonastyrskyjDouglas MorganJanet Lorraine MorrisonLynne Carol MossIsamu (Sam) MukaiAlex J. MunroJames Edward MurphyLorraine Neill-WacowichLeona M. NelsonMelvin NevilleBev NicholsKathleen (Kay) NicholsonFausto Cesare NicolaJoanne O’BrienRegina O’GradyJanet OrkuszMartha OrnestJoan Elizabeth OslerHelen PapleyDr. Alan PatersonJeanette PaulAndy PennockMarion Irene Perkins-RogalskyWanda PetersonGeorge PichGreg PikeMar PitstraWilliam PolglaseMaurice PombertLeslie PopowichIris W. PorterVirginia Alice PorterDianne M. PrechtEd ProdorErnie PyeNancy QuaalePaul RadomskiAnnabelle Rector

John RedmondJudy RemeikaCameron RichardsonNeil R. RiddellCarol RisplerEthel & David RodgersWillma Lawson RodgersVasile (Valerica) RomanStewart RothwellJuliet RushClive RutlandMarley RyndSusan SaikTerry SaikRizieri SarnoRandall G. ScheirerVictor SchieweDavid SchmelkeWilliam John SchmirlerKlaus Dieter SchulteReid Glen SchwabeAndre SchwabenbauerMarie Valerie SchwartzMaurice (Moe) SchwartzDarlene Patricia ScottDonald C. ScottEvelyn Virginia (Ev) SeamanMelvin SemeniukDennis SernesTeresa SgarbossaHugh ShawcrossAudrey Doreen SherleyVince ShierGeorge ShyryDavid SimpsonLuciana SivertsonMarguerite SmallwoodClark H. SmithFay SmithGlenda Louise SmithGordon SmithDennis SoprovichClifford James SorensonAntonio SpadaforaWilliam SpringsteinNicholas (Nick) A. StarkVivian StarkPatricia SteblykGregg SteenbergenBetty StevensMax StilesRaymond StoneAnna Marie StrackEugene SullivanJohann Hill Moreton SvrcekHeather SweeneyBrian SydorBob TarrLaura June TaylorAndrea Nadene Thiessen-SchoffWilliam (Bill) Thoman

Val ThomasGary ThompsonPatricia TimmerJames “Gordon” TraubDr. Harvey TreleavenMarie TriggsMarie TrofimukHailey UpshallHelen UrselEllen Louise Van BeekArt VandaleNorman VandenhoutenJune VennerJames VermetteLes VogtDoug VolkRemigio VolpiDennis WagnerBryan Jack WalbauerSue WaltersGerald WardTerri Leanne WardDr. John WatersFrieda Gladys WebbWilhelmina WebbDon WedderburnGen WeinmayrReta WeirJoan WestermarkHertha WetterJustafellow—Michael WheatonCarol WheelerRobert WhitesideDavid Warren WhitingLois WilkinsBernhard (Bernie) WinterLarry YackimecPeter & Barbara YaremaMee Ching YeeRobert (Bob) YostJim YouellEd ZdanowiczLynne Zenko

in HonourAnonymous (2)Mary Grace BlockMatthew Cook & friendsKali Cousins“Bunny” CreaseyJohannes & Agatha de GoeijKeith & Lenora DeeringShirley GroslandDianne HughesJohn KosnikWendy MartinMichael MillenaarLarry OstermayerDaryl RangerDave & Jennifer StobyEllen Louise Van Beek

Remembering a loved one, friend or colleague with a gift to the Alberta Cancer Foundation is a lasting and meaningful memorial tribute. It is also a unique way to express your regard on a special occasion. Please

contact the Alberta Cancer Foundation for more information, or to notify us of any errors or omissions.

Stepping up to Alberta’s Cancer Free Future ��

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Prevent cancers. Save lives. Eliminate suffering.

17th Annual Cross Cancer Institute Golf Classic $606,20014th Annual Tom Baker Cancer Centre Golf Classic $364,000Stem Cell Awareness Charity Golf Tournament $325,60510th Annual Row for Life $146,000Providing a Voice $126,439Celebrating Betty’s Life $121,5587th Annual Playing for Life $114,1005th Annual Laughing for Cancer $100,2518th Annual Short Cut to the Cure $84,396Edmonton Northlands Horse Show—Bringing Home the Dream $78,940Fountain for Youth at WEM $76,00013th Annual Boston Pizza Charity Golf Classic $54,000PricewaterhouseCoopers Cancer Fundraiser

—In honour of Daryl Ranger $51,0211st Annual Digital Communications / IGL Canada /

Mancap Group / MLC Group Charity Golf Classic $50,9401st Annual Look Homes Building Cures for Kids Campaign $50,855Bald Legals Cancer Fundraiser $45,2693rd Annual Bryan Mudryk & Friends Charity Golf Classic $42,500Bre Barrett / United Controls “United Guys Head Shave” $32,5781st Annual Pigeon Lake Pedal—Push the Cure for Cancer $32,178Head Shave—In honour of the Kali Cousins $29,7106th Annual Floyd Mehalcheon Memorial Trail Ride $29,1803rd Annual SnowBall $27,055Debra Cantalini-Gallant Breast Cancer Golf Classic

Title Sponsor Royal LePage Community Realty $27,000Homerun for Life $26,5002nd Annual U of A Engineering Head Shave $26,338Rendezvous Salon & Spa—A Rendezvous for Cancer $26,057Scona for Cancer $25,452Goin Strong—A Celebration for Jeff Goin $25,0001st Annual RBC Phyllis Andrietz Memorial Golf Tournament $23,140U of A Law School Cuts for a Cure $22,5222nd Annual Linaria & District Kids with Cancer Fun Golf $22,00010th Annual Darren Howard Memorial Slo-Pitch Tournament $20,98811th Annual Alberta Mobility Golf Tournament $20,498Thunder Energy Thunder Thys Fundraiser $20,32614th Annual Fort Saskatchewan Motorcycle Association

Cancer Ride & Rally $20,000Harry Ainlay Cuts for Cancer $19,600Butch Fischer Golf Tournament $19,082Donna Brenneis’s Cancer Fundraiser $19,0588th Annual Uniglobe Geo Sue Foy Memorial Golf Classic $17,0002nd Annual Kissi Ki Yaad Mein Fundraiser $16,544Spruce Grove Legion #281 Head Shave $16,505City of Calgary Law Department Cancer Challenge $16,0486th Annual Blair Oko Charity Golf Classic $16,000CyclePath Head Shave $15,231Providing a Voice Cancer Month Kickoff Head Shave $14,430Mary Block’s Selfless Gift Head Shave—In honour of Phil Christie $14,050Ladies Bread & Putter Golf Tournament &

Head Shave at Pots Bar & Grill $13,9214th Annual Muskeg River 500 km Bicycle Ride $13,470CBC Downtown Sundown Run & Walk $13,4325th Annual Lumberjack’s Auction & Fundraiser $13,373Something’s Cooking … In Southern Italy $11,650Alberta Sports Vision Institute Hockey Tournament $11,300Lister Hall Students’ Association Locks for Love $11,250Vegreville EMS Short Cut to the Cure $10,973Cowboy Ride for Cancer $10,8334th Annual Booster Juice Main Squeeze Family Run & Walk $10,5166th Annual Dennis Soprovich Memorial Volleyball Tournament $10,500

2nd Annual Dennis Sernes Memorial Slo-Pitch Tournament $10,500Millet Days Short Cut to the Cure $10,302Sheena Gascon Head Shave $10,273Parkland EMS Short Cut to the Cure $10,124Annual Alberta Sports Vision Institute Golf Tournament $9,935Spencer Giese & Friends Shave-a-thon $8,297Mulligans for Life Golf Tournament $8,0003rd Annual Butterfly Boutique Golf Tournament $7,930Camp He Ho Ha Staff Head Shave $7,401Queen Elizabeth Junior High School Cuts for Cancer—Part 2 $7,3143rd Annual Short Cut Through the Park $7,261Annual Ralph Hole Jr. Memorial Golf Tournament $7,00015th Annual Wesclean Golf Tournament $7,0005th Annual Jackie Davey Memorial Golf Tournament—EWI $7,000Liliana’s Boutique Celebration of Life Fundraising $6,796Simone Curry Head Shave $6,465Kotowich Home Hardware Building Centre Golf Tournament $6,400Yard Clean Up and “Crew” Cut—Steeplejack Industrial Group $6,390Northern Riders Iron Butt Run $6,068Franco’s Family Dining Charity Golf Tournament $5,7009th Annual Prime West Employee Golf Tournament

—In memory of Mr. Clare Johnson $5,610Soroptomists Fundraising for Arts in Medicine $5,500Dennis & Cathy Quinn Head Shave $5,4833rd Annual JH Picard High School Cuts for Cancer $5,415The Cookbook Co. Cooks Fundraising Dinner $5,380Gilles R. Tetreault & Neil Smith Head Shave $5,364Sprott Securities 6th Annual Charity Golf Tournament

—In memory of Andy Luthin $5,2853rd Annual Country Sampler—Bosom Buddies Fundraiser $5,260U of A Golden Bear Open Head Shave $5,2502nd Annual Salisbury Greenhouse Ladies Night Out $5,100Tapestry Retreat Foundation Head Shave $5,066allRewards.com $5,0003rd Annual Optimists Cures for Kids Radiothon $5,000Gaudet’s Fresh & Frozen Seafood Raffle $5,000Courtenay Kids Clip for Cancer $4,852Wesclean Equipment Golf Tournament $4,8002nd Annual Wetaskiwin Wal-Mart Short Cut to the Cure $4,600WestJet Retro Night Fundraiser and Head Shave $4,500St. Hilda’s Catholic Jr. High School Cut for Cancer $4,487Ascension: 3 Peaks Scramble $4,450Janice Lumley Head Shave $4,414Lily Goodbrand’s Cut for Cancer $4,331Myrna Hood’s Dread then Shed Cash for Cancer Campaign $4,258Mark & David Cameron’s Cut for Cancer $4,147Tammy Bell Head Shave $4,0827th Annual Elite Taekwondo Break-a-thon $4,081Jim Noble’s 2nd Annual Dining for Dollars & Rhapsody in Blue Jeans $4,042Calgary Co-op Bags to Riches $3,925Inside Education 20th Anniversary Silent Auction $3,800Queen Elizabeth Jr. Sr. High School $3,798NAIT Providing a Voice Head Shave $3,750Suede Lounge Cancer Care/Treatment Fundraiser $3,6701st Annual Baker Boys Street Hockey Tournament—Scoring for Cancer $3,5904th Annual Mulhurst Bay Walk $3,530Conchita Reyes We Are That Someone CD Sales $3,50014th Annual Riverton Trail Ride $3,5003rd Annual Rosie’s Deer Meadows Golf Tournament $3,5004th Annual TBCC Basement Staff Arts & Crafts Show & Sale $3,4243rd Annual 4 Wing Cold Lake Garage Sale $3,375Cam Borgland & Mike Hoare Head Shave $3,325

Alberta Cancer board and Foundation 2005/2006��

Each year, hundreds of special volunteers and participants generously give their time and talents to raise funds on behalf of the Cross Cancer Institute, the Tom Baker Cancer Centre and 15 other cancer centres throughout the province. In 2005/2006, more than 300 community events and friendraisers were held and supported by thousands of Albertans. Collectively, more than $4 million was raised to benefit cancer research, prevention and care in our world-class cancer centres. Our sincere thanks and congratulations to the organizers and participants of the following special events.

Special events

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4th Annual Cougar Tool Golf Tournament $3,2201st Annual SNC Lavalin Golf Tournament $3,180Allison Carr’s Cut for Cancer $3,135Sacred Heart School Short Cut to the Cure Run $3,089Parkallen School Laps for Loonies $3,047Dance Because You Care $3,0113rd Annual Gregg Steenbergen Memorial Golf Tournament $3,000Northland Village Wal-Mart Fundraiser—In memory

of Margaret Farrish and in honour of Jim Robinson $3,000Black Swan Christmas Cancer Drive $2,980Centcom Construction Golf Classic $2,975Lisa Ross-Rodriguez’ Short Cut for Cancer $2,970Calgary Sewfest $2,915Blessed Sacrament School Head Shave $2,906McCarthy Tetrault Jeans Days $2,821The Langley Keg Greg Pike Memorial $2,816Thomas Hess Dahlia Sale $2,790Christ the King School Cuts for Cancer $2,680Debbie Benoit and Canadian Blood Services Head Shave $2,660Mark Schwabenbauer Head Shave $2,660Graeme Bouwmeester Head Shave $2,5852nd Annual Robert Deatherage Memorial Hockey Tournament $2,5008th Annual Sawmill Ladies Golf Tournament $2,5002005 Calgary Playboy Scramble $2,5002nd Annual Delta Kappa Epsilon Invitational Charity Golf Tournament $2,350IPS Stampede BBQ Fundraiser $2,3458th Annual Eula Klask Memorial Golf Tournament $2,3223rd Annual Centennial Banquet & Catering Mother’s Day Brunch $2,3201st Annual Daffodil Dinner & Dance $2,312Laurie Moore Head Shave $2,285Margaret Creasey 80th Surprise Birthday Celebration $2,275Corrine Slator Head Shave $2,180Drew’s Walk $2,150Catherine Coakes & Friends Head Shave $2,082Evelyn Kaplan Head Shave $2,055Ryan Nall’s 16th Birthday Fundraiser with St. Pius X Church $2,0537th Annual Healy Ford / Alberta Mustang

Owners’ Association All Ford Classic Show $2,019United Cycle Annual Bike Expo $1,951Mohawk for Munchies $1,896Alyssa Kelly’s Carnival for Cancer $1,896Nikki’s Cuts for Cancer—In honour of Gale Small $1,8862nd Annual Aubro Services Golf Tournament $1,820Phyllis Baerg Head Shave—P&B Office Supplies $1,807Larissa Vos “Bye Bye Hair, Bye Bye Cancer” $1,8052nd John & Kathy Budd Golf Tournament $1,803Shave or Save Tanner Mack’s Hair $1,800Hanna Farmers Bonspiel $1,800Cristo’s CD Sales $1,7733rd Annual Edmonton Police Service Traffic Section Pin Sale $1,760Christmas Cancer Swan Dive Fundraiser $1,755Botticelli Restaurant Pasta Fundraiser $1,740Iris Gosselin Head Shave $1,735Myrnam Crooked Shooters Hockey Club Annual

Mixed Slo-Pitch Tournament $1,733Rosanna Helm Golf Tournament $1,730Brian Ukrainec Skullet and Head Shave $1,7006th Annual Boomerang Bash $1,600DonateACarCanada.com $1,591784 Wing Head Shave $1,582Inland Audio Visual Golf Tournament $1,560Kaella Young Head Shave $1,528Steve Stamhuis Head Shave $1,523Jilly’s Home & Lifestyle Girls Night Out $1,5221st Annual Playboy Scramble $1,510Great Human Race $1,496Dave Wright & Jason McKerracher Head Shave $1,470Picture This! Framing & Gallery ‘Masterpieces in Minature’ Show $1,400Chris Bauwens Head Shave $1,400Play Back Pub Fundraiser $1,400Megan Reville Head Shave $1,400Dave Lester Memorial Golf Tournament $1,400ECCO Shoes Cuts for Cancer $1,370Chachkas Breast Cancer Fundraiser $1,357Medicine Hat Cancer Centre Cookbook Sale $1,340Leduc Protective Services Short Cut to the Cure $1,317Dan Okrusko Head Shave—In honour of Pam Herstad & John Kosnik $1,290NBCC 7th Annual Charity Golf Tournament $1,275Mark Broadfoot & Friends Head Shave $1,270

Alouette of Edmonton South Customer Appreciation $1,264Brandon Groff & Marc Sywenky Head Shave $1,230Sir George Simpson Jr. High School Staff Fundraiser $1,221Devon United Church—The Extreme Team Famine $1,207Vernon Barford Christmas Bazaar—In memory of Glenda Smith $1,202Matthew Burgoyne Run for Cancer $1,187Kerry Noel Head Shave $1,170Scott Morrison’s Cut for Cancer $1,160Anthony Schulmeister Head Shave $1,150Calgary Produce Marketing Association $1,150Adam Burns Head Shave—In memory of Pauline Berube $1,1152nd Annual Arth’s Fashion Centre Raffle $1,097Diamond International Trucks Golf Tournament $1,094Boschman Girls Head Shave—In honour of Helen Baerg $1,090Paul McIntosh Head Shave $1,031Wade Screpnek Head Shave $1,025Jason Gregor & The Team 1260 NHL Hockey Draft $1,020Matt Cook Hockey Fundraiser $1,012Petro-Canada Wildcat Hills Gas Plant—In honour of Diane Hughes $1,001Grande Prairie Keg Restaurant Golf Tournament

—In memory of Wanda Petersen $1,000An Evening with the Legends $1,000St. Ambrose Petal Pushers Pen Sales $1,000Carole Ann Erickson Christmas Gathering $9701st Annual U of A Accounting Club Golf Tournament $965Trojan Industries Inc. Golf Tournament $920Ruby Plamondon’s Walk-a-thon and Chili Supper $905Kathleen Dye Sunflower Bears $900Vernon Barford School Fundraising—Active Month $895Theresa Thomas Head Shave $870Anthony Purgas & Bryan Jonzon Wedding $855ING Edmonton Marathon $810Bowness High School Graduation Class $800Jasmine Rothweiler Cut for Cancer at Camilia School $793Clayton Noble Head Shave $784Head Shaving Bee for Breast Cancer Research $780Charity Concert at the Last Chance Saloon $777Talieya Lewis’s Cut for Cancer $765Brenda Engel Haircut Event $750REIN Golf Tournament—In honour of Michael Millenaar $735Amelie Poitras Head Shave $731Jake Daniels Making the Cut 2005 $730Lillian Upright Garage Sale $724Semchuk Family Reunion $713S&P Backhoe Services Car Wash $708Cancer Benefit Show—Bassics Production $705Conrad Handle Bar Sales—1664 BMX $700Steven Hamagami Head Shave $7003rd Annual Circle K Volunteer Club—U of A—Topless Car Wash $700KDM Management Golf Tournament $680Brentwood Elementary School “Canada Day” Fundraiser $659Gord Kozens Memorial BBQ—MES Bus Maintenance $657Lloyd Sadd Insurance Monthly Charity Campaign $6552nd Annual Joyce Balanecki Memorial Golf Tournament $650Milo & District Agricultural Society/Snake Valley Hoedown $650Sifton Elementary School Spelling Bee $631Allen Bradley 60th Birthday $615Lindsay Soltice Head Shave $614Cook Heifer Raffle $610Anita Aurora Wedding $590Summer Gonzalez’ First Hair Cut $5875th Annual Gerber-Getchell Handicapped Golf Tournament $580Massages by Shayne Stevenson $570Heather Lawrence Cancer Fundraiser $529CerTech Automotive Repair $525Zach Bosch Head Shave $520Michael Gorman’s Birthday $517Edmonton Moravian Church 100th Anniversary Mother/Daughter Tea $511The Chow Brothers Fundraiser $510“The Bald and the Beautiful” Head Shave—Justine Danis $507RCMP K Division Christmas Party $505Kensington Floors Head Shave $504Westjet Car Wash & Bake Sale $502Jeanine Hoffart’s Bicycle Ride for Charity (Calgary – Edmonton) $501Garden of Beaden Fundraising $500Parkallen Knitters Annual Show and Sale $500The Garden of Beaden $500Fraternal Order of Eagles #2098 $500

Stepping up to Alberta’s Cancer Free Future ��

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Alberta Cancer Board and Foundation 2005/200648

Cross Cancer Institute11560 University AvenueEdmonton, AB T6G 1Z2Phone: 780-432-8771

Tom Baker Cancer Centre1331 – 29 Street N. W.Calgary, AB T2N 4N2Phone: 403-521-3723

Associate Cancer CentresCentral Alberta Cancer Centre3942 – 50A AvenueP.O. Bag 5030Red Deer, AB T4N 4E7Phone: 403-343-4526

Lethbridge Cancer CentreRoom 2H209960 – 19 StreetLethbridge, AB T1J 1W5Phone: 403-329-0633

Grande Prairie Cancer Centrec/o Queen Elizabeth II Hospital10409 – 98 StreetGrande Prairie, AB T8V 2E8Phone: 780-538-7588

Medicine Hat Cancer Centre666 – 5 Street S.W.Medicine Hat, AB T1A 4H6Phone: 403-529-8817

Community Cancer CentresBarrhead4815 – 51 AvenueBarrhead, AB T7N 1M1Phone: 780-674-2221

Bonnyvillec/o Bonnyville Health Centre5001 Lakeshore Drive, P.O. Bag 1008Bonnyville, AB T9N 2J7Phone: 780-826-3311

Camrose Community Cancer Centrec/o St. Mary’s Hospital4607 – 53 StreetCamrose, AB T4V 1Y5Phone: 780-679-6100

Bow Valley Community Cancer Centrec/o Canmore General Hospital1100 Hospital PlaceCanmore, AB T1W 1N2Phone: 403-678-7226

Drayton ValleyDrayton Valley Community Cancer CentreCrossroads Hospital & Health Centre4550 Madsen AvenueDrayton Valley, AB T7A 1N8Phone: 780-542-5321

Drumheller Community Cancer CentreDrumheller District Health Services351 – 9 Street NWDrumheller, AB T0J 0Y1Phone: 403-823-6500

Fort McMurray Community Cancer Centrec/o Northern Lights Regional Health Centre7 Hospital StreetFort McMurray, AB T9H 1P2Phone: 780-791-6161

High River Community Cancer Centrec/o High River General Auxiliary Hospital560 – 9 Avenue WestHigh River, AB T1V 1B3Phone: 403-652-2200

Hinton Community Cancer Centrec/o Hinton General Hospital1280 Switzer DriveHinton, AB T7V 1V2Phone: 780-865-3333

Lloydminster Community Cancer CentreLloydminster Hospital3820 – 43 AvenueLloydminster, SK S9V 1Y5Phone: 306-820-6144

Peace River Community Cancer Centrec/o Peace River Community Health Centre10101 – 68 Street, Bag 400Peace River, AB T8S 1T6Phone: 780-624-7500

Cancer Care CentresThe Cross Cancer Institute in Edmonton and the Tom Baker Cancer Centre in Calgary deliver comprehensive patient care and treatment, undertake research and provide education opportunities to health-care professionals.

Alberta Cancer BoardProvincial Office1220, Standard Life Centre10405 Jasper AvenueEdmonton, AB T5J 3N4P 780-412-6300

Alberta Cancer FoundationProvincial Office1400, Standard Life Centre10405 Jasper Avenue, Edmonton, Alberta T5J 3N4 P 780-409-5700Toll-free in AB 1-866-412-4222F 780-409-5724albertacancer.ca

The Annual Review and complete financial statements are available online at albertacancer.ca.

Possible­­—Albe­­rta’s Cance­­r Fre­­e­­ Future­­ Albe­­rta Cance­­r Board and Foundation 2005­/2006 Annual Re­­vie­­w

ISSN 1911-4729Layout and Design: Perpetual Notion, Tina TomljenovicPhotography: Darren Jacknisky, Bluefish Studios Trudie Lee, Trudie Lee PhotographyWriters: Anne Bailey, Brian Bergman, Kathy Classen, Phoebe Dey, Lee Elliott, Rhonda Lothammer