Position available

Cell, Vol 56. No. 1, January 13. 1989

Positions Availab le

Cell Classified Information Cell publishes classified advertisements for positions available, and for announcements of meetings, symposia, and courses. Rates are $225 for a quarter page, $425 for a half page, and $795 for a full page. We will accept either camera-ready material or copy for typesetting. Deadlines for the next available issues are as follows (all material due close of business on due date):

*Feb. 10, 1989 issue: copy due Jan. 6, 1989 *Feb. 24, 1989 issue: copy due Jan. 20, 1989 *Mar. 10, 1989 issue: copy due Feb. 3, 1989 *Mar. 24, 1989 issue: copy due Feb. 17, 1989 *Apr. 7, 1989 issue: copy due Mar. 3, 1989 *Apr. 21, 1989 issue: copy due Mar. 17, 1989 *May 5, 1989 issue: copy due Mar. 31, 1989 a May 19, 1989 issue: copy due Apr. 14, 1989

*June 2, 1989 issue: copy due Apr. 28, 1989 *June 16, 1989 issue: copy due May 12, 1989 *June 30, 1989 issue: copy due May 26, 1989 *July 14, 1989 issue: copy due June 9, 1989 *July 28, 1989 issue: copy due June 23, 1989 *Aug. 11, 1989 issue: copy due July 7, 1989 *Aug. 25, 1989 issue: copy due July 21, 1989 *Sept. 8, 1989 issue: copy due Aug. 4, 1989

Advertisements should be sent to: Allison Kemmerer

Classified Ad Department Cell

50 Church Street Cambridge, MA 02138 (617-661-7059).

Faculty Position in Molecular Biology Tuskegee University

The Department of Biology at Tuskegee University invites applications from molecular biologists who use molecular genetic approaches to study fundamental problems in biology. The position is at the senior faculty level and is available immediately. A completely equipped biotechnology laboratory is available to the appointee. Our search will consider candidates in all areas of molecular biology research. Applicants should have a doctoral degree, postdoctoral experience, and proven ability for independent research. The appointed candidate will join an active graduate program and is expected to develop a strong independent research program. Please forward curriculum vitae, a research proposal, summary of teaching interests, and three references to: Dr. J.H.M. Henderson Chairman of the Molecular

Biology Search Committee Department of Biology Tuskegee University Tuskegee, Alabama 36088.

Faculty Position Department of Genetics University of Washington

The Department of Genetics seeks candidates for a tenure track appointment at the rank of assistant or associate professor, to begin in 1989 or 1990. The successful applicant will have a notable record of achievement in basic research and a strong commitment to both undergraduate and graduate education. Areas of particular interest to the Depart- ment include neurogenetics, mammal ian genetics, and plant molecular genetics. Applicants should arrange to have three letters of recommendation sent and should submit a curriculum vitae and a brief description of research interests by March 1, 1989, to:

Search Committee Department of Genetics, SK-50 University of Washington Seattle, W A 98195.

The University of Washington is an Equal Opportunity/ Affirmative Action Employer.

Cell, Vol. 56. No. 1, January 13. 1989

UMDNJ-Graduate School o f Biomedical Sciences

Graduate Program in Biochemistrv and Mo lecular Biology Department o f Biochemistry Robert Wood Johnson Med ical School (formerly Rutgers Med ical School)

D irector: Masayori lnouye Associate D irector: R ichard A. Berg

FACULTY RESEARCH INTEREST

Edward Arnold Structure &function of molecules in living systems; x-ray crystal graphic studies of proteins

Richard A. Berq Barbara Brodskv Kiran Chada Richard H. Ebright

Requlation and genetic expression of connective tissue proteins Protein conformation and interactions: x-ray diffraction studies of collaqen Developmental qene expression in transqenic mice Relationship of protein structure to protein function; protein-ligand interaction; protein-nucleic acid interaction: protein enqineerinq

Masavori lnouve Sumiko lnouye

Control of qene expression: membrane bioqenesis; protein enqineerinq Molecular biology of myxobacteria, development-specific gene expression & biosynthesis of branched RNA-linked MSDNA

Daniel Klessiq John Lenard Peter Lobe1 Paul March Fumio Matsumura Joachim Messinq N. Ronald Morris Scot-l Powers Dannv Reinberq Martin Rosenberg

Gene expression in plant and animal cells and their viruses Membrane structure and function Intracellular traffickinq of proteins Molecular bioloqv of membrane function: siqnalinq mechanisms and protein secretion Function of microfilaments in cell transformation Regulation of qene expression in hiqher plants Biochemistry of mitosis: molecular aenetics; pharmacoloqv of microtubules Signal transduction and qrowth control in yeast Mechanisms of requlation of RNA polvmerase II transcribed qenes Regulation of gene expression in human adenoviruses, human immunodeficiency viruses, and in bacteriophaqes

Monica Roth Absorption, replication, and inteqration of murine retroviruses Aaron Shatkin Virus replication, regulation of eukarvotic transcription and translation Tai Wai Wonq Mitochondrial DNA replication and transformation Martin L. Yarmush Applied immunoloqv, bioseparations, protein science and enqineerinq and artificial organs

This Program will provide the opportunity to do research at Robert Wood Johnson Medical School, Rutgers University, Center for Advanced Biotechnology and Medicine, and the Waksman Institute, leading to a Ph.D. degree. An M.D./Ph.D. program is available.

Graduate Student Stipends will be $1 l,OOO/year plus tuition and benefits.

Prospective students for September, 1989 should write to: Dr. Richard A. Berg, Associate Dean, UMDNJ-Robert Wood Johnson Medical School, Graduate School of Biomedical Sciences, 675 Hoes Lane, Piscataway, NJ 08854 for more information and an application form.

Cell, Vol. 56, No. 1, January 13. 1989

Postdoctoral Research Position

Molecular Mechanisms of Mammal ian Cell Growth Control

Mayo Clinic/Mayo Foundat ion

A postdoctoral position is available January 1, 1989 to study the molecular and cellular biology of peptide growth factors. Specific areas of research include the identification and cloning of growth factor-regulated genes and the delineation of specific protein-DNA interactions involved in transcriptional control. Applicants should possess a strong background in one or more of the following areas: recombinant DNA methodology; protein biochemistry; mammal ian cell culture techniques. Send curriculum vitae and three references to:

Dr. Michael J. Getz Department of Biochemistry and Molecular Biology Mayo Clinic/Mayo Foundation Rochester, MN 55905.

An Equal Opportunify/Affirmative Action Institution.

Research Assistantships Institute for Biotechnology Texas Tech University

The newly formed Institute for Biotechnology at Texas Tech University announces the creation of research assistantships for graduate study leading to the Ph.D. degree in the areas of biochemistry, cell biology, genetics, microbiology, or molecular biology. Beginning in the SPRING of 1989, a total of five assistantships in the amount of $12,000.00 per year are being offered by the Departments of Biological Sciences, Chemistry & Biochemistry and Agronomy, Horticulture & Entomology. Interested applicants should apply for admission into one of the three departments before February 1, 1989. Those students seeking admission for Spring 1989 are encouraged to apply as m as possible. For more information, contact:

Dr. David B. Knaff, Director Institute for Biotechnology P.O. Box 4260 Texas Tech University Lubbock, TX 79409.

Staff Positions Med ical Research Council

Laboratory of Mo lecular Biology

The Division of Cell Biology has several indcpcndcnt research positions available in the general areas of Developmental, Cell and Molecular Biology. We are looking for outstanding candidates regardless of their precise research interests.

Appointmentsarefor3.5years,andcanlead toa tenured position. There are no administrative or teaching responsibilities. Rcsearchat the laboratoryiisfunded by a block grant from the Medical Research Council, and excellent facilities are provided.

Applicants, who should have at least two years postdoctoral cxpcrience, should send a C.V. and short statement of research interests to:

Jonathan Hodgkin or Hugh Pelham MRC Laboratory of Molecular Biology Hills Road, Cambridge CBZ 2QH England. Tel. (0223) 248011

Postdoctoral Position Cellular/Molecular Biology Sloan-Kettering Institute

A postdoctoral position is available starting summer 1989 after this laboratory relocates to the Sloan-Kettering Institute in New York City. This laboratory concentrates on the TGF-P family growth and differentiation factors (see Cell 48: 409; 49: 437; 51: 189; Science 240: 196). Research program includes: molecular characterization of growth factor receptors, identification of signalling mechanisms, regulation of cell adhesion receptor expression by growth factors, and regulation of the expression of normal and neoplastic phenotypes. A strong background in molecular biology is highly desirable. Applications with names of three references should be sent to:

Dr. Joan Massague Department of Biochemistry University of Massachusetts Medical School 55 Lake Avenue North Worcester, MA 01655.

Cell, Vol 56, No. 1, January 13. 1989

Faculty Position Mutagenesis/Carcinogenesis/Genetic Toxicology Oregon State University

The Oregon State University Environmental Health Sciences Center and Department of Agricultural Chemistry jointly seek an individual with postdoctoral experience to fill an assistant professor position available July 1989. The primary responsibility will be to develop a strong research program focused on mechanistic aspects of mutagenesis and carcinogenesis, preferably using the approaches of molecular biology. Emphasis on mammal ian processes is desirable, but not mandatory. Interaction with molecular biologists and other faculty in the Department of Agricultural Chemistry and the Center for Gene Research, and with the faculties of the Environmental Health Sciences Center and the graduate Toxicology Program is encouraged. There will be ample opportunities to supervise Ph.D. students and to participate in graduate and undergraduate education, but no formal teaching requirements for three years.

Send curriculum vitae, a description of research interests, and a list of at least three references by February 1, 1989 to:

Genotoxicology Search Committee Department of Agricultural Chemistry Oregon State University Corvallis, Oregon 97331.

Oregon State University is an Affirmative Action/Equal Opportunity Employer and complies with Section 504 of the Rehabilitation Act of 1973. OSlJ has a policy of being responsive to the needs of dual-career couples.

Faculty Position Cell Biologist Princeton University

We are soliciting applications for an assistant professorship as part of our program to strengthen molecular and biochemical cell biology at Princeton. The position will be in the Department of Biology which resulted from the recent fusion of the pre-existing Departments of Biology and Molecular Biology.

Submit a brief description of proposed research program, curriculum vitae, and a list of references to:

Dr. J. E. Rothman c/o L. Abele Department of Biology Lewis Thomas Laboratory Princeton University Princeton, NJ 08644-1014.

Princeton UniversiQ/ is an Equal Opportunity/Affirmative Action Employer.

Assistant or Associate Professor University of California, Irvine

The University of California, Irvine, Cancer Center/ Division of Hematology/Oncology is seeking a faculty member at the level of assistant or associate professor. Must have strong background in medical oncology and molecular biology and a major interest in clinical trials and basic laboratory research in the discipline. The University and Hospital have recently made substantial commitments to the development of the cancer center and opportunity for rapid and expanded professional growth is high.

Please submit curriculum vitae and five references to:

Dr. Frank Meyskens Cancer Center UCIMC Route 81 101 City Drive South Orange, CA 92668.

UC/ is an EOP/AA Employer.

Cell. Vol. 56, No. 1, January 13. 1989

Assistant Professor-Molecular Virolog)( University of Texas Southwestern Medical Center

The Department of Microbiology at the University of Texas Southwestern Medical Center invites applications for an assistant professor position (tenure track). The successful candidate will be expected to establish an independent research program. Candidates committed to investigation in oncogenic viruses or human retroviruses are preferred. Excellent departmental facilities include a to be-constructed P3 laboratory. Significant opportunities exist within the department for collaborative research in molecular biology, immunology, and oncogenic viruses and outside the department with a Hughes Institute, Cancer Center, and Center for Diabetes Research. Send curriculum vitae, names of three references, and a brief statement of research plans to: Jonathan W . Uhr, M.D. Department of Microbiology University of Texas Southwestern Medical Center 5323 Harry Hines Boulevard Dallas, TX 752359048. An Affirmative Action/Equal Opportunity Employer.

Medical Staff Fellowship in Molecular Genetics at NIH

The Molecular Genetics Section of the Genetrcs and Brochemistry Branch, National Institute of Diabetes, and Digestrve and Krdney Diseases, Natronal lnstrtutes of Health, is offering a Medical Staff Fellowshrp in Molecular Genetrcs. Applications are Invited from rndrvrduals of the hrghest caliber wrth the M.D. or M.D.. Ph.D. degrees. Applicants should have two years of clinical experience and research experience IS preferred. Applrcatrons are being accepted now for appointments which begtn July 1989. The appointment IS for two years and can be extended for a third year. Medical Staff Fellows receive an Initial salary of $32,000, with Increments of $2,000 per year.

The Medrcal Staff Fellow may participate in the NIH lntennstrtute Medical Genetics Program as well as carry out research in basic molecular genetics. Current research interests include the biochemistry of eukaryotic recombination, cell-free systems for the study of immunoglobulin rearrangements, the study of mutants defective in genetic recombination, gene targeting and gene disruptron in mammal ian cells and the molecular brology of Tay-Sachs disease.

Interested candrcates should submit their curriculum vrtae and biblrography to:

Dr. R. Daniel Camerinr-Otero Chtef. Genetics and Biochemistry Branch National lnstrtute of Diabetes and Digestive and Ktdney Diseases Building 10, Room 9D-15 National lnstrtutes of Health 9000 Rockville Pike Bethesda, Maryland 20892

An Equal Opportunity Employer

Faculty Positions Sloan-Kettering Institute Cell Biology and Genetics Program

The Sloan-Kettering Institute invites applications for several tenure-track junior and senior faculty positions in the Cell Biology and Genetics Program. This research program is one of four in the Institute, and is undergoing a major expansion in research at the molecular level in the areas of positive and negative growth control, differentiation, cell structure, intercellular recognition, and morphogenic pattern formation. The Cell Biology Program and the Molecular Biology Program at the Sloan-Kettering institute are jointly relocating to a new research building which also houses advanced facilities for protein and nucleic acid microchemistry, transgenic mice, and automated mammal ian cell micromanipulation. The faculty members of the Cell Biology and Genetics Program are also affiliated as faculty with the Cell Biology Graduate Program at Cornell University Medical School. The positions offered are highly competitive with regard to start-up funds, laboratory space, salary, and housing. Eligible candidates should have a doctoral degree, postdoctoral experience, and demonstrate potential and ability to develop an independent, imaginative research program. Formal applications are invited from junior as well as established investigators. Applications should include a curriculum vitae, a list of publications, a summary of research activitiecand research plan, and the names of three or more references. Applications should be addressed to: Dr. Joan Massague Cell Biology and Genetics Program Sloan-Kettering Institute 1275 York Avenue New York, NY 10021.


RESEARCH FELLOWSHIP

Three year postdoctoral fellowships are available to work on the molecular mechanisms of oncogene function, regulation, and cooperation in Dr. H. Land’s Laboratory at the Imperial Cancer Research Fund, London, England.

Two main areas of research are being pursued, The first concerns the function and control of the myc oncogene. The second involves the analysis of the molecular mechanisms that underly oncogene cooperativity between ras and various nuclear oncogenes. In particular, we are presently isolating genes involved in controlling different aspects of oncogene cooperativity by genetic complementation. The function and interaction of these genes in the control of cellular proliferation and differentiation will be studied.

Candidates should have experience in molecular biology, recombinant DNA technology, and tissue culture. The fellowship will be tenable for three years. Salary range is f14,OOO to f 17,000 depending upon qualifications and experience.

For further details contact: Dr. H. Land, on 011 44 1 242 0200 ext. 2240.

Application should be made by sending full curriculum vitae with names and addresses of three referees to The Recruitment Officer, Imperial Cancer Research Fund, Lincolns Inn Fields, London WCPA 3PX, quoting ref. 27/R. Smoking is actively discouraged.

I M P E K I A L CANCER RESEARCH FUND

Predoctoral and Postdoctoral Training in Virology at UCLA School of Medicine

The Department of Microbiology and Immunology, UCLA School of Medicine, invites applications for training positions in virology. Research programs include the cellular and molecular basis of latency and pathogenesis of herpes simplex viruses (Jack G. Stevens), molecular biology of influenza viruses, transport and sorting of eukaryotic proteins (Debi P. Nayak), gene regulation and transformation by papil loma viruses (Felix 0. Wettstein), molecular mechanism of viral persistence (Rafi Ahmed), molecular biology of picornaviruses and regulation of eukaryotic transcription (Asim Dasgupta), molecular genetics and pathogenesis of human retroviruses (Irvin S.Y. Chen), and molecular basis for transcriptional activation of herpesvirus genes (Lawrence T. Feldman). Stipends available. For predoctoral training leading to the Ph.D. degree, contact: Dr. Rafi Ahmed; and for postdoctoral positions, contact: Dr. Debi P. Nayak, Department of Microbiology and Immunology, UCLA School of Medicine, Los Angeles, CA 90024-1747. An Equal Opportunity/Affirmative Action Employer.

UNDERGRADUATE RESEARCH OPPORTUNITIES

Fred Hutchinson Cancer Research Center, Seattle Summer 1989

The Division of Basic Sciences faculty invite qualified undergraduates to apply for summer research positions in molecular and cellular biology. Research in the Division’s 28 laboratories spans the entire spectrum of modern biology including cellular, molecular, and developmental biology, oncogenes, genetics, molecular immunology, membrane biology, and virology.

Students are supported by fellowships from the Center. Completed applications are due March 1, 1989. For further information and application forms write:

Associate Director, Division of Basic Sciences Fred Hutchinson Cancer Research Center

1124 Columbia Street Seattle, W A 98104.

The Fred Hutchinson Cancer Research Center is an Equal Opportunity/Affirmative Action Employer. M/F/H.

Cell, Vol. 56, No. 1, January 13, 1989

POSTDOCTORAL TRAINING IN VIROLOGY

FREDHUTCHINSONCANCERRESEARCHCENTER UNIVERSITY OF WASHINGTON

Several postdoctoral positions funded by an NIH grant are available in the areas of molecular biology of viruses and oncogenes. Investigators participating in th program include:

Hutchinson Center

#Jon Cooper: viral/cellular oncogenes *Robert Eisenman: retroviral oncogenes; retroviral

replication *Denise Galloway: papillomavirus and herpesvirus gen

regulation *Adam Geballe: cytomegalovirus gene regulation *Mark Groudine: retroviral oncogenesis; gene regulatio *Maxine Linial: retroviral replication and

transformation *Dusty Miller: retrovirus biology and gene transfer *Paul Neiman: retroviral oncogenesis; B-cell ontogeny *Jim Roberts: viral and cellular DNA replication *Larry Rohrschneider: viral/cellular oncogenes *Gerry Smith: bacteriophage recombination

University of Washington

*Jim Champoux: papovavirus and retrovirus replicatior *Michael Katze: viral translational control *Julie Overbaugh: retroviral pathogenesis *Tim Wong: retroviral and measles virus gene

expression

In addition, research opportunities are available in a new program in HIV molecular biology (Groudine, Neiman, Roberts, Linial, Eisenman, Miller, Geballe, Katze, Overbaugh). Interested applicants should send a curriculum vitae and names of three references directly to the faculty member of interest at: Fred Hutchinson CancerJlesearch Center, 1124 Columbia Street, Seattle, WA 98104. or: University of Washington, Department of Microbiolog X-42, Seattle, WA 98195.

General inquiries about postdoctoral positions can be directed to: Virology Training Program, c/o Jan Smitt Fred Hutchinson Cancer Research Center.

An Equal Opportunity/Affirmative Action Employer.

unfrsiw Delaware

Assistant Professor Microbiology - Molecular Virology University of Maryland at Baltimore

Tenure track position is available immediately for an animal virologist (Ph.D. or M.D.) with training and research interest in molecular genetics, especially in using viruses as gene vectors. The appointee is expected to establish an independent research program within an expanding academic department with research activities in molecular and cellular immunology immunopathology of viral infections including HIV, and pathogenesis of rickettsial and parasitic diseases.

Send curriculum vitae, description of research interests, list of publications, and names and addresses of references to:

Dr. Gerald Cole Department of Microbiology and Immunology University of Maryland School of Medicine 660 West Redwood Street Baltimore, Maryland 21201.


Uriiversitv

FACULTY APPOINTMENT PLANT MOLECULAR BIOLOGIST

BIOCHEMISTRY DEPARTMENT, UNIVERSITY OF MISSOURI-COLUMBIA

The Biochemistry Department of the University of Missouri, Columbia invites applications for a tenure track faculty position at any level of seniority in plant molecular biology or plant biochemistry. The Department has strong programs in plant enzymology, microbiology, molecular biology, and phytohormones, and members have extensive and productive interactions with faculty in other departments. We seek candidates with strong individual research programs in any area of plant molecular biology.

Applications from qualified members of minority groups and women are strongly encouraged. Ail applications must be received no later than February 1, 1989 in order to receive full consideration. Please send a curriculum vitae, a statement of research interests, and three letters of reference to: Dr. R. 0. Morris, Chairman, Search Committee, Biochemistry Department, 322A Chemistry Building, University of Missouri, Columbia, MO 65211. Telephone: (314) 882-5186.

The University of Missouri is an Affirmative Action/Equal Opportunity Employer.

Postdoctoral Position

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

A postdoctoral research position for a Ph.D./M.D. is available in the Section on Hormone Metabolism and Action to study molecular mechanisms of hormone action including gene expression, protein-DNA interactions, and thyroid hormone receptors,

Interested candidates should send their curriculum vitae and names of three references to:

V. Nikodem, Ph.D. National institute of Diabetes and Digestive

and Kidney Diseases National Institutes of Health Bldg. 10, Rm. 8N317 9000 Rockville Pike Bethesda, Maryland 20892.

An Equal Opportunity Employer.

Director Biotechnology Synthesis Facility University of Utah Medical Center

The University of Utah Medical Center is developing an interdepartmental facility for oligonucleotide synthesis, peptide synthesis, protein sequencing, etc., and is recruiting a director for the facility. Qualified candidates should have a strong background in chemistry and/or molecular biology and be experienced with HPLC and other instruments. The University has strong, interactive research programs in molecular and cellular biology. Outdoor recreation opportunities (skiing, camping, etc.) are excellent wd close by. Salary is negotiable. Closing date is February 1, 1989. Send a curriculum vitae and three letters of reference to:

Dr. David Stillman Department of Cellular, Viral, and Molecular Biology University of Utah Medical Center Salt Lake City, Utah 84132.

Equal Opportunity/Affirmative Action Employer.

Ceil, Vol. 56, No. 1, January 13. 1989

POST DOCTORAL

FELLOW Position available in laboratory involved in research on molecular basis of cell proliferation in animal cells. PhD or equivalent. W rite to:

Dr. Renato Baserga

Bl

Dept. of Pathology Temple University Medical School Philadelphia, PA 19140

!i!iEkF Equal Opportunity, Affirmative Action Employer

Graduate Research Opportunities at the Fred Hutchinson Cancer

Research Center

Opportunities for graduate research are available in the Basic Sciences Division of the Fred Hutchinson Cancer Research Center in a wide spectrum of modern biology including cellular biology, molecular immunology, molecular biology, membrane biology, genetics, and virology. The Basic Sciences Division consists of 28 interactive laboratories conducting basic research using a wide variety of model organisms including bacteria, yeasts, protozoa, nematodes, insects, amphibians, and mammals. Students interested in Ph.D. research at the Center may apply through the Interdisciplinary Molecular and Cellular Biology Program of the University of Washington. Degrees are granted from the participating University departments in which many of the Basic Sciences Division faculty members hold appointments. Application deadline is Feb. 1 for admission in Sept. 89. For application materials and further information please contact: Office of the Associate Director, Division of Basic Sciences, Fred Hutchinson Cancer Research Ctr., 1124 Columbia St., Seattle, W A 98104; (206)467-4617. An AA/EOE. M/F/H.

DIRECTOR, DIABETES RESEARCH INSTITUTE Diabetes Center of Eastern Virginia

Eastern Virginia Medical School

Position Reopened and Redefined

Eastern Virginia Medical School announces the reopening of the search for the Director of the Diabetes Research Institute of the Diabetes Center of Eastern Virginia (DCEV). The DCEV is a comprehensive program of the Department of Internal Medicine of Eastern Virginia Medical School that integrates research, education, and clinical care. The role of the Diabetes Research Institute within the DCEV is to develop and conduct major research activities. The Director must have a Ph.D. or M.D. and be a leader in the field of diabetes research with expertise in molecular biology, cellular biology, receptors, second messengers, or immunology. The successful candidate must demonstrate ability to obtain extramural funding as well as the potential to continue growth over the next ten years. The Director of the Diabetes Research Institute will be expected to recruit a team of prominent scientists and develop a comprehensive program in diabetes research. The Director will also function as a member of the DCEV executive management team. Salary is competitive; full faculty status and benefits are available. Significant financial support to establish the Research Institute has been raised through aggressive local and national fund raising efforts. Interested candidates should reply by March 1, 1989, but the position will remain open until filled. Please forward curriculum vitae and the names of three individuals to be used as references to: Michael J. Dimino, Ph.D., Associate Dean for Research and Academic Planning, Chairman, Search Committee, Eastern Virginia Medical School, P.O. Box 1980, Norfolk, VA 23501. The Medical Coliege of Hampton Roads is an AA/EOf.

Cell, Vol. 56. No. 1, January 13, 1989

Associate or Full Professor Molecular Biology The University of Alabama

The Department of Biology, The University of Alabama, invites applications for a position at the ASSOCIATE or FULL PROFESSOR level. Candidates currently at the assistant and associate professor level are encouraged to apply. The successful candidate must have demonstrated a consistent record of publication and funding in the area of eukaryotic gene regulation. Research interests of current faculty include membrane biochemistry, protein processing, nucleic acid and protein structure/function analysis, and gene regulation and evolution. Salary will be competitive and generous set-up funds are available. Review of applications will begin February 1. Applicants should submit a curriculum vitae, statement of research interest(s), and the names of at least three references to: Dr. John K. Hardman Department of Biology The University of Alabama Tuscaloosa, AL 35487-0344. The University of Alabama is an Equal Opportunity Employer.

Faculty Position in Immunology Assistant Professor, Tenure Track University of Nebraska-Lincoln

Requires postdoctoral experience and demonstrated research capability. Will be expected to establish an independent, externally-funded research program focusing on a significant problem in immunology, using molecular or genetic approaches. Teaching responsibilities might include an undergraduate/graduate course in immunology or a graduate-level course in area of interest. Position available for fall 1989. Send curriculum vitae, statement of current and future research interests, and three letters of reference to: Dr. Dwane Wylie Immunology Search Committee School of Biological Sciences University of Nebraska-Lincoln Lincoln, Nebraska 68588-0118.

Applications will be reviewed January 30, 1989, but will be accepted until a suitable candidate is found.

An Affirmative Action/Equal Opportunity Employer.

Molecular and Cellular Aspects of Endocrinology Banting and Best Department of Medical Research

University of Toronto

The Banting and Best Department of Medical Research, University of Toronto, is seeking candidates for the position of assistant professor (tenure stream). The position is available July 1, 1989 and will carry an initial appointment of five years at a competitive salary.

Candidates should have a strong research background and be prepared to develop a research program in molecular and cellular aspects of endocrinology (for example - mechanisms of signal transduction, surface and intracellular receptors, growth factors, diabetes research, regulation of gene expression). The successful candidate will be expected to attract independent research grants, to spend at least 75% of his/her time in research, and to participate in graduate and’ undergraduate training. The University of Toronto encourages both women and men to apply for positions.

Applicants should forward a curriculum vitae, an outline of research interests, and arrange for three letters of reference to be sent directly to:

Dr. David H. MacLennan Professor and Chairman Banting and Best Department of Medical Research University of Toronto 112 College Street Toronto, Ontario, Canada M5G 1 L6.

In accordance with Canadian immigration requirements, priority will be given to Canadian citizens and permanent residents of Canada, but foreign applications are encouraged.


DIRECTOR

School of Biological Sciences University of Nebraska-Lincoln

The University of Nebraska-Lincoln invites nominations and applications of highly qualified individuals for the position of Director, School of Biological Sciences, and Professor with tenure.

The School has a broad range of active research programs from molecular to whole organism biology with emphases in ceil and molecular biology, ecology and evolutionary biology, and plant sciences. The successful candidate will lead the School at a particularly dynamic period of growth and development, helping to fill several tenure-leading positions and influencing the development of newly established, state funded research initiatives that include the Centers for Biological Chemistry, for Biotechnology, and for Microbial Ecology. The School presently consists of 34 budgeted faculty, 80 faculty associated with the graduate program, approximately 80 graduate students, and 500 undergraduate majors.

Candidates must have an excellent record of research achievement, a successful record of extramural funding, a Ph.D. in biological sciences or related fields, a commitment to undergraduate and graduate education, and demonstrated administrative potential to provide leadership to guide continued development of the School’s diverse research and teaching programs. Salary negotiable.

Please submit a letter of application, current curriculum vitae and other pertinent material, including evidence of leadership and administrative potential as well as names, addresses, and telephone/telex numbers of five references postmarked by February 20 (or until a suitable candidate is identified) to:

Dr. Anthony Joern, Search Chair Director of Biological Sciences

c/o Dean’s Office College of Arts & Sciences

University of Nebraska-Lincoln Lincoln, Nebraska 68588-0312

Telephone: (402) 472-2724 FAX: (402) 472-2410.

Affirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSITIONS

TWO POSTDOCTORAL POSITIONS (M.D. OR Ph.D.) are available in the National Institutes of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Public Health Service, to investigate gene expression during repair of bone and cartilagenous tissues. Studies will evaluate mRNA expression for structural and regulatory genes in models of normal or impaired healing, correlate observations with histological events, and explore the effect of exogenous growth factor administration on the repair process. The applicant should have a background in biochemistry, molecular biology, or orthopedics. Starting date is flexible. Salary is $20,000 to $50,744 per annum depending on experience. Send curriculum vitae and three letters of reference to: Mark E. Bolander, M.D., Orthopaedic Research Unit, Bldg. 30, Rm. 414, 9000 Rockville Pike, Bethesda, MD 20892. US Citizenship required.

++ ‘k+> Q 2 z 6%

5 LT

AN EQUAL OPPORTUNITY

0, 4 HE+- EMPLOYER

POSTDOCTORAL RESEARCHER

Genentech, Inc., a leader in the field of biotechnology, has a postdoctoral position currently available in our Molecular Immunology Department. The position will involve expression cloning of novel proteins of potential therapeutic interest, primarily through the use of fluorescence activated cell sorting (FACS). In addition, the candidate will undertake studies involving random mutagenesis screening by FACS to engineer new recombinant molecules Candidates must be highly motivated with experience in molecular biology as a prerequisite. Prior experience with FACS is not a requirement. Genentech offers an excellent salary and benefits package coupled with the opportunity to make a significant contribution to our organization. For consideration, please send your resume to: Yvonne Davino, Human Resources Department GA, Genentech, Inc., 460 Pt. San Bruno Blvd., South San Francisco, CA 94080. An Equal Opportunity Employer. Women and minorities are encouraged to apply.

Ceil. Vol. 56. No. 1, January 13, 1969

Faculty Positions in Molecular Genetics Wake Forest University Medical Center

Applications are invited for several tenure track faculty positions in an interdisciplinary Program in Molecular Genetics at the Wake Forest University Medical Center. Preference will be given to candidates whose research interests lie in the general areas of regulation of gene expression and genetic approaches to studying protein structure/function relationships. Opportunities exist for interaction with ongoing research programs in protein structure, membrane biology, immune regulation, neuroscience, developmental biology, lipoprotein and arterial wall metabolism, cancer, inflammation, aging, diabetes mellitus, and pathogenesis by infectious agents. Academic rank for these appointments will be commensurate with the experience of the candidate. Send curriculum vitae, summary of research interests, and names of three references to: Dr. Moseley Waite, Chairman, Molecular Genetics Steering Committee, Wake Forest University Medical Center, Winston- Salem, NC 27103. Equal Opportunity/Affirmative Action Employer.

ELECTRONMICROSCOPIST

Columbia University

A position is available for an electronmicroscopist for Cancer Center core facility with transmission and scanning electronmicroscopes. Successful candidate should have experience with fixation, embedding, and sectioning techniques and with procedures for visualization of nucleic acids.

Send resume and names of references to:

Dr. ELF. Erlanger or

Dr. Samuel Silverstein c/o Department of Microbiology

Columbia University 701 West 188th Street New York, NY 10032.

L

Staff Position The Research Institute of The Hospital for Sick Children

The Research Institute of The Hospital for Sick Children offers a staff position in its Division of Biochemistry Re- search. A major biomedical research organization, the Institute has over 150 Principal Investigators and 200 trainees in strong programs that range from basic to clinical studies. Initial appointments are for three-year periods, moving to five-year renewable appointments. The Institute is based on a firm, long-term endowment income; its research is exciting, collaborative, and is supported by a full range of services. There is the potential for cross-appointment to the University of Toronto. We are seeking a Ph.D. with at least three years of postdoctoral experience in the application of modern techniques of physical biochemistry to protein structure and function. The applicant should be prepared to develop a strong independent research program. Applicants should forward a curriculum vitae and an outline of research interests, and should arrange for three letters of reference, all to be sent to: Dr. H. Schachter, Head, Div. of Biochemistry Research, The Hospital for Sick Children, 555 University Ave., Toronto, Ont. MSG 1X8.

Staff Scientist in lmmunopathology Responsible to lead a team of postdoctoral fellows, grad uate students, and research technicians involved in the study of the genetic programs that underlie T-cell function and activation under normal and pathological con- ditions. Min imum requirements include a Ph.D. degree in immunology or pathology with special emphasis on molecular biology and human retrovirology, together with significant expertise in molecular cloning, sequencing, computerized primary and secondary structural analysis, recombinant protein expression in eukaryotic systems, and functional assays in immunological cells. Also required is significant prior expertise, as demonstrated by research or publications, with construction and characterization of genomic and cDNA libraries, the study of the regulation of gene expression using transient and stable transfection assays, nucleic acid- protein binding assays, in vitro transcription and translation systems, and in viva expression as assessed by Northern blots, Sl mapping, Western blot, immuno- precipitation, and two-dimensional gels. Salary range is $3!, 160 to $40,000 per year for a five day 40 hour work week. Qualified applicants respond with resume to: J. 0. #9155, Division of Employment Security, Charles F. Hurley Building, Boston, MA 02114.


Assistant Professor Biochemistry and Molecular Biology Louisiana State University

The Department of Biochemistry and Molecular Biology, Louisiana State University School of Medicine in Shreve- port invites applicants for two tenure track positions at the assistant professor level. We are seeking candidates with a strong background in molecular biology, molecular genetics, protein biochemistry, and physical biochemistry. We especially encourage applicants whose research interests are focused in mammal ian and yeast cell systems; however, outstanding candidates in other areas of molecular biology and biochemistry will defin- itely be considered. The Department currently has well funded research programs studying gene expression and regulation in prokaryotic and eukaryotic systems, yeast genetics, molecular virology, and protein chemistry. Letters of application, including curriculum vitae, a statement of future research interests, as well as three letters of reference should be sent by February 15, 1989 to: Dr. Richard J. Courtney, Chairman, Department of Biochemistry and Molecular Biology, LSU Medical Center, 1501 Kings Highway, Shreveport, LA 71130. An Affirmative Action/Equal Oppohnity Employer.

Faculty Positions Section of lmmunobiology Yale University

The Section of lmmunobiology seeks applicants for several ladder faculty positions at the level of assistant professor in the general area of immunobiology. Qual- ified applicants in all areas of immunology are invited to apply, and would be expected to develop an indepen dent research program using molecular, cell biological, or biochemical approaches to immunobiological problems. They will also be expected to participate in departmental teaching at both the graduate and undergraduate levels. Candidates should submit a curriculum vitae with a summary of present and future research interests, and request that three letters of recommendation be sent no later than February 15, 1989 to: Dr. Richard Flavell, Chairman Section of lmmunobiology Yale University School of Medicine 310 Cedar Street P.O. Box 3333 New Haven, CT 06510. An Equal Opportunity/Affirmative Action Employer. Women and minority candidates are encouraged to apply

Group Leaders Plant Molecular Biology

Toulouse - France The Laboratoire de Biologie Moleculaire des Relations Plantes-Microorganismes CNRS-INRA in Toulouse is seeking to recruit two group leaders. The laboratory is located close to the Toulouse University campus, the second largest in France for Science and Technology. At present there are nine groups working on the molecular genetics either of the Rbizobium-legume symbiosis or of plant diseases caused by bacteria or viruses, The laboratory is to be enlarged in 1989 and two permanent positions for senior scientists will be created. The app- ointees will have to develop groups working on plant genes involved in plant-microbe interactions, Excellent scientific credentials and at least four years of postdoctoral research experience in cellular and molecular biology are required. Annual salary will be in the range of FF 150,000-200,000 depending on qualification and experience. Further information may be obtained from: Dr. Georges Truchet, Laboratolre de Biologie Molec- ulaire, CNRS-INRA, BP27,31326 Castanet-Tolosan Cedex, France, to whom applications including a curriculum vitae and the names of three referees should be sent. Closing date February 28, 1989.

Faculty Position in Developmental Biology University of California, San Francisco

Candidates are sought for a tenure track faculty position at the assistant professor level, but appointments at a more senior level will be considered. The successful applicant will be expected to conduct a research program that combines classical, genetic, and/or molecular approaches to problems in developmental biology. In addition, participation in the teaching activities of the Graduate Program in Developmental Biology and the Anatomy Department will be expected. Applicants should send curriculum vitae, bibliography, with copies of publications and a summary of research plans, and should arrange to have three letters of recommendation sent to: Chairperson Developmental Biology Search Committee Department of Anatomy University of California, San Francisco San Francisco, CA 94143-0452. Applications should be received by January 31, 1989. Affirmative Action/Equal Opportunity Employer.


RESEARCH ASSOCIATE

MOLECULAR BIOLOGY OF CYTDKINES Labor&o

The x of Medical Biochemistry

ockefeller Univetsitv Independently conduct molecular and genetic

research in ongoing projects to characterize macro- phage-derived inflammatory mediators and immuno- modulatory monokines. The highly motivated scientist we seek will have demonstrated competence in applied molecular biology including cDNA cloning and expression, gene regulation, PCR applications and hybridization techniques. Must demonstrate competence to coordinate all molecular biological approaches in the efforts of a multidisciplinary team exploring the biochemistry, cell biology, immunology, in vivo functions and clinical importance of several newly-discovered cytokines.

Salary commensurate with research experience and leadership abilities. The Rockefeller University is an Equal Opportunity/Affirmative Action Employer and Invites applications from all qualified individuals. Please contact:

Anthony Cerami, Ph.D. Professor and Head, Laboratory of Medical Biochemistry The Rockefeller University

1230 York Avenue, New York, NY 10021 3%.

Ip&‘i ;g;KEFE-LER 1 hTrr,ly $

~zx* UNIVERSITY ’ -i,r ‘z ‘IL IJ .

Postdoctoral Position Mammal ian Developmental Genetics

The Markey Center for Developmental Genetics

Case Western Reserve University

A postdoctoral position supported by the Lucille P. Markey Foundation is available to study site-directed mutagenesis of proto-oncogenes, growth factor and receptor genes in mouse embryo-derived stem cells. The manipulated stem cells will be injected into blastocyst-stage embryos to create germline chimeras from which lines of mice carrying the mutated genes will be established. Applicants should have a strong background in molecular genetics with an interest in mammal ian developmental genetics. Please send curriculum vitae and three reference letters to: Dr. Hsing-Jien Kung, Department of Molecular Biology and Microbiology, or Dr. Terry Magnuson, Department of Genetics, Case Western Reserve University, School of Medicine, 2119 Abington Road, Cleveland, OH 44106. Case Western Reserve Universit] is an Equal Opportunity/Affirmative Action Employer.

Postdoctoral Positions Molecular Biology of Human

Retroviruses

Howard Hughes Medical Institute at Duke University Medical Center

Several positions are available starting in the summer or fall of 1989 to work on the role and the mechanism of action of the rat, rev, and nef trans-activators of HIV-l. Applications are invited from highly motivated individuals with backgrounds in molecular and/or cellular biology. Experience in the area of protein:RNA interactions would be particularly welcome.

Please send curriculum vitae, and names of three references to:

Dr. Bryan R. Cullen Box 3025 Howard Hughes Medical Institute Duke University Medical Center Durham, North Carolina 27710.

Postdoctoral Fellowship Cedars-Sinai Medical Center

The Medical Genetics Birth Defects Center, Division of Medical Genetics at Cedars-Sinai Medical Center in Los Angeles, has a postdoctoral fellowship position available.

The primary focus of the laboratory is the understanding of the molecular basis of connective tissue diseases and the structural and functional consequences of collagen gene mutations.

Ph.D. with experience in molecular biology, protein chemistry, and cell culture highly desirable.

Please submit resumes with references to:

Mark W . Schmitz CEDARS-SINAI MEDICAL CENTER Employee Relations Department Br&n Bldg., 1 st Floor 8700 Beverly Boulevard Los Angeles, CA 90048.


The Upjohn Company is currently seeking a highly motivated research associate for its Hairgrowth Research Group, to participate in studies a imed at elucidating mechanisms that promote growth in hair and/or skin. Qualified applicants will have a B.S. degree and several years’ experience or an MS. in a relevant biological science. Evidence of training or expertise in skin and/or hair growth biology and ability to work independently as well as to collaborate with members of a multi-disciplinary research team are desirable. This position will conduct jn viva research with animals and primates to characterize structural derangement in the skin and hairfol- licles of animal mode ls, will develop improved assays to quantitatively evaluate stimulation or inhibition of hair growth by chemical agents in these mode ls and must be skilled in administration of drugs to ani- ma ls, collection and preparation of skin and hair including sectioning and staining for examination at the light m icroscopic level. Experience in modern morphologi- cal techniques such as computerized image analysis, immunohistochemistry and/or autoradiography is also desirable.

EXPERIMENTAl? MORPHOLOGIST

Upjohn commits 14% of annual sales to funding research efforts and our strengths include worldwide marketing excellence and new emphasis placed upon joint ven- tures. We are located in southwestern M ichigan, m idway between Chicago and Detroit. Upjohn offers advancement opportunities, a highly competitive salary, comprehensive benefits and relocation as- sistance. For prompt confidential consideration, please call from outside of M ichigan toll free l /800-253-8600, ext. 3-6767, (inside M ichigancallcollect 616/323-6767) to request an emp loyment application be sent to you. Please refer to advert isement number 23690-HA when calling. We are an Equal Opportunity Employer M /F.

Our Commitment to Scientific Excellence Continues...

POSTDOCTORAL FELLOWSHIPS PCR-DNA

AMPLIFICATION Cetus. the pioneer of the Polymerase Chain Reaction and a frontrunner in Biotechnology, IS seeking applications for two Postdoctoral Fellowships to study the structure and function of thermostable DNA Polymerases

Efforts WIII be dlrected toward Improved understanding of the Polymerase Cham Reaction (PCR) E e DNA amplification technique and extending the applications for thermostable DNA Polymerases Responsibllltles Include detalled characterization of kinetic propertIes, such as extension rate. processivity. displacement synthesis and fldellty. The successful applicant will have the opportunity to collaborate with the highly motivated CETUS PCR Group

We requre a Ph.D. in Biochemistry or Molecular Biology and up to 3 years’ dwctly relevant experience in nucleic acid enzymology. Preference will be given to highly creative, exceptionallyproductlvesclentlstswithexper~encestudylng kmetic propertles of DNA Polymerases and with fldellty assays. Experience with antibody-affinity chromatography would be an asset. Excellent wntten commumcatlon skills areessentlal. Thlsposltlonw~ll bea2yearappolntment and may be extended to 3 years by mutual agreement.

Cetus offers competitive salaries and excellent benefits For lmmedlate and confidential consideration, please send your CV to Cetus Cortxxation. 1 h Box DG, 1400 53kd St&, Emetyville, CA 94608. We are an Equal Opportumty Employer

Assistant Professor Department of Biology

Case Western Reserve University

A tenure track faculty position at the assistant professor level is available in the area of

CELL, MOLECULAR BIOLOGY

Applicants will be considered with research interests in plant or animal systems, who have a strong commitment to research and undergraduate and graduate education. Interested persons should submit curriculum vitae plus a statement of current research interests, and have three letters of recommendation sent to:

Dr. Norman B. Rushforth Chairman

Department of Biology Case Western Reserve University

Cleveland, OH 44106.

Case Western Reserve University is an Equal Opportunity/Affkmative Action Employer.

Cell. Vol. 56, No. 1. Januaty 13. 1989

THE RESEARCH INSTITUTE OF SCRIPPS CLINIC

Ph.D. Program in

Macromolecular and Cellular Structure and Chemistry

The Research lnstltute 01 Scripps Cllmc will admit ilve to ten highly qualiifed students m rhe wmrner 01 1989 to begIn studies ior a Ph.0 in this ~mponant contemporary area of biological science.

Candidates for this program must have earned a bachelor’s degree or higher and have a strong background in biology and chemistry. Hfghly q&fled appl~ants WIII be asked to “lilt the Research lnst,tute ior an ,nter- view. All students accepted fnio the program will receive fnxncn sup- pi.

lndlvlduals Interested in applying ior this program should send a letter descrlblng their scent~f~c interests and goals as well as a resume or curriculum vitae to:

Dean of Graduate Studies, ~66 The Research Institute of Scripps Clinic

10666 North Torrey Pines Road La Jolla, CA 92037

Thts graduate program IS supported in pan by lunds irom The Rock- efeller Foundation and 15 author,zed by the Cal,fornia Stare Department of Education.

Assistant/Associate Professor Prokaryotic M icrobial Genetics University of Hawaii

The Department of Microbiology, University of Hawaii is seeking applicants for a tenure track (9 month) assistant/associate professor position in the area of prokaryotic microbial genetics to begin August 1, 1989. A Ph.D. in microbiology or a related field, at least two years of postdoctoral experience, a strong record of research funding or potential for funding, and a strong attraction to teach at both the undergraduate and graduate levels in microbial genetics and microbiology are required. Application deadline: February 15, 1989. Submit curriculum vitae, names of at least three references, and representative publications, if available, to: Dr. Philip C. Loh Chairman Department of Microbiology University of Hawaii Honolulu, HI 96822 (808) 948-8603. An Equal Opportunity Employer.

Virologist North Carolina State University

The Department of Microbiology, North Carolina State University, has available a research and teaching position as assistant professor in virology. A Ph.D. degree with emphasis in plant, bacterial, or animal virology and relevant postdoctoral experience are required. The position is a 12-month tenure track appointment and includes continuing institutional research support. The successful candidate is expected to teach, direct graduate students, and develop a vigorous research program in a basic aspect of virology. Excellent opportunities exist for collaboration with other virologists on campus and in the Research Triangle Area.

Applications are invited from qualified individuals with expertise in virology. Included in the application should be a statement of research interest, curriculum vitae, and list of publications. In addition, provide the names, addresses, and telephone numbers of three individuals who may be contacted for a reference by the search committee. Indicate your professional association with each referee. Application materials should be sent to: Dr. Thoyd Melton Virology Search Committee Department of Microbiology Box 7615 North Carolina State University Raleigh, NC 276957615. The closing date for applications is February 28, 1989 or until a suitable candidate is selected. Proper documentation of identity and employability will be required before the-hiring process can be finalized.

North Carolina State University is an Equal Opportunity Employer.

Cell. Vol. 56, No. 1, January 13, 1989

Postdoctoral Research Seattle Biomedical Research Institute

Postdoctoral research on antigen genes of Leishmania and TIypanasoma cruzi. Emphasis is on cloning and expression of genes coding for antigens specific for T cells, and diagnostic antigens. Candidates with an interest in basic and applied research in tropical disease, including international collaboration, are encouraged to apply. Experience in molecular biology/protein biochemistry would be helpful. Seattle Biomedical Research Institute is a multidisciplinary non-profit research institute specializing in infectious diseases. Send curriculum vitae and names of three references by March 15, 1989 to:

Steven Reed, Ph.D. Seattle Biomedical Research Institute 4 Nickerson Street Seattle, WA 98109 (206) 284-8846.

Equal Opportunity Employer.

UNIVER$ITY i@JELPH

Postdoctoral Fellowship in Virology

A postdoctoral position is available to conduct research in the mechanism of birnavirus gene expression (for recent review, see J. Gen. Virol. 69: 1757, August 1988). A strong background in molecular biology is required. Experience in the area of recombinant DNA (cloning, sequencing, site-directed mutagenesis) as well as computer literacy is essential. Salary is commensurate with experience. The position is renewable up to three years. Please send curriculum vitae, publication list, and names, addresses, and telephone numbers of three references to:

Dr. Peter Dobos Department of Microbiology University of Guelph Guelph, Ontario Canada Nl G 2Wl.

The University of Guelph is committed to Employment Equity.

Postdoctoral Position Molecular Neurobiology Postdoctoral position available for an individual interested in applying molecular genetic approaches to the study of the development, maturation and aging of the nervous system. Specific areas of concentration include: analysis of synapsin gene structure and expression; molecular analysis of the genes involved in X- linked neurological disorders (Rett Syndrome, Retinitis Pigmentosa); analysis of neuron- specific gene expression in Alzheimer’s disease and normal aging. Requirements: Background in molecular genetics. Interested individuals should see Haas and DeGennaro, (1988) J. Cell Biol. 106:195-203. Send vitae and names of three references to Dr. Louis DeGennaro, University of Massachusetts Medical Center, Department of Neurology, 55 Lake Avenue North, Worcester MA 01655. UMMC is an equal opportunity/affirmative action employer.

UNIVERSITYOFMASSACHUSET'IS MEDICALJ,.#&CENTER

@ii v&@

Postdoctoral Positions NH,-Terminal Protein Processing

(Yeast)

Openings for two Ph.D.‘s, who are well-trained in yeast genetics or cell biology, to study: (i) the biosynthesis, regulation, and sorting of yeast aminopeptidases (Chan & Smith, submitted [cloning & sequencing of aminopeptidase I]) and (ii) the biochemistry and cell biology of acetylation (Lee et al., J. Biol. Chem. 263: 14948, 1988 [isolation & characterization of No-acetyltransferase]); Lee et al., submitted [cDNA]) and removal of acetylated amino acids (Kobayashi & Smith, J. Biol. Chem. 262: 11435, 1987 [isolation & characterization of acyl-peptide hydrolase]; Kobayashi et al., submitted [cDNA], Lin et al., submitted [genomic DNA]). You will join a dynamic team of fellows, who have cloned the genes needed for studying the functional role of these and other enzymes in protein synthesis and degradation and will be appointed as a Research Fellow in Genetics at Harvard Medical School. Call or write: Dr. John A. Smith, Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114; Telephone: 617-726-5954.

Cell. Vol. 56, No. 1, January 13, 1989

Tenure Track Research Positions Medical College of Wisconsin Eye Institute

The Medical College of Wisconsin invites applications for two full time tenure track research positions at both senior and junior faculty levels. Requires Ph.D. or M.D. and at least two years postdoctoral research experience. Must establish competitive, funded programs in eye research. The Medical College is expanding in areas of cell biology, molecular biology, immunology, neuroscience, and transplantation. Applicants with interests that may complement these areas are encouraged to apply.

Send curriculum vitae, summary of research interests, and names of three references to:

Search Committee Medical College of Wisconsin Eye Institute 8700 W. Wisconsin Avenue Milwaukee, WI 53226.

Affirmative Action/Equal Opporlunity Employer, M/F/H.

POSTDOCTORAL FELLOW

Molecular Biology of Lung Development

University of Rochester

A position is available July 1, 1989 in an NIH-supported laboratory program to study mechanisms of hormone effects on gene expression during development of lung cells.

Qualifications: Ph.D. with background in molecular biology. Please contact:

Dr. Donald L. Shapiro Department of Pediatrics (Box 651) University of Rochester School of Medicine 601 Elmwood Avenue Rochester, NY 14642 Telephone: 716-275-5884.

An Equal Opporiunity Employer M/F.

Faculty Positions in Molecular and Cell Pathobiology The University of Texas Health Science Center at San Antonio

The Department of Pathology at The University of Texas Health Science Center at San Antonio is opening a search for several full-time tenure track faculty members interested in experimental pathology and teaching. We wish to expand in the areas of molecular and cellular approaches to studies of carcinogenesis and the regulation of cell growth and differentiation. Candidates will be considered for both junior and senior faculty appointments.

Faculty rank will be commensurate with prior academic experience and accomplishments. The Department is fully integrated, comprising anatomic, clinical, and experimental pathology divisions with major responsibilities in patient care and the teaching of medical, graduate, dental, and allied health professionals. Currently, the major areas of experimental pathology research in the department include renal and cardiovascular injury, atherogenesis, mediators of inflammation, pulmonary disease, and membrane protein biosynthesis. Applicants should have a doctoral degree in biomedical sciences (M.D., Ph.D., D.V.M., D.D.S.) with a demonstrated ability or potential to develop an independent investigative career and be interested in actively participating in the teaching and/or clinical programs within the department or in graduate programs of other departments within the Graduate School of Biomedical Sciences.

Submit curriculum vitae and references to: David S. Papermaster, M.D., Professor and Chairman, Department of Pathology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78284-7750. Telephone: (512) 567-4000.

An Equal Opportunity/Affirmative Action Employer.


SAMUEL ROBERTS NOBLE FOUNDATION PLANT MOLECULAR BIOLOGY

RESEARCH FELLOWSHIPS Applications are invited for three Noble Foundation Fellowships for postdoctoral research in Plant Molecular Biology. These fellowships are for 3 years, one beginning May 1989, the others in November 1989. They are a key element in a collaborative program between the Plant Biology Division, Noble Foundation, Ardmore, and the Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California. Collaborative projects in the laboratories of Richard Dixon (OK) and Chris Lamb (CA) include: a. Characterization and expression of plant

defense response genes. b. Trans-act ing regulatory proteins and

signal molecules for defense gene activation.

c. Elucidation of mechanisms for engineer ing enhanced stress resistance.

At least one year will be spent in each laboratory. Please send resume and 3 letters of recommendation to: Dr. R.A. Dixon, Director, Plant Biology Division, S. Ft. Noble Foundat ion, P.O. Box 2180, Ardmore, OK 73402.

Telephone: (405) 223-5810, Ext. 321 Equal Opportunity Employer

lllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllll

POSTDOCTORAL POSITIONS

The Pennsylvania State University

Postdoctoral positions are available to study transcriptional and posttranscriptional regulation of protein synthesis in liver and skeletal muscle. Positions require experience in protein chemistry, tissue culture, and gene expression in mammal ian cells.

Send curriculum vitae and three letters of reference to:

Dr. Leonard S. Jefferson Chairman

Department of Physiology College of Medicine

The Pennsylvania State University Hershey, PA 17033.

An Affirmative Action/Equal Opportunity Employer.

UNIVE&ITY &GUELPH

Chair - Department of Zoology College of Biological Science

Nominations and applications are invited for the Chair of Zoology in the College of Biological Science. The candidate should be an outstanding scholar with a strong commitment to excellence in graduate and undergraduate education. The Department of Zoology has 30 faculty members with diverse research interests, particularly in ecological and physiological aspects of fisheries, marine, and wildlife biology. Approximately 60 graduate students are enrolled for the M.Sc./Ph.D. degrees and 300 students are specializing in the four departmental undergraduate programs. The College of Biological Science is currently reorganizing its curriculum. It requires an academic with strong leadership skills as the Chair of the Department of Zoology to meld the considerable strengths within the department, to recruit new faculty, and to provide direction for the 1990’s. Candidates should submit a curriculum vitae, a list of publications, and the names of at least three referees to:

Dr. Bruce H. Sells Dean College of Biological Science University of Guelph Guelph, Ontario, Canada Nl G 2W1.

Deadline for receipt of applications is February 28, 1989. Subject to final budgetary approval. In accordance with Canadian Immigration requirements, priority will be given to Canadian citizens and permanent residents. The University is committed to Employment Equity.


Postdoctoral Position in Molecular Biology University of California, San Diego

A postdoctoral position is available to study a novel system of regulation of gene expression and DNA replication by silicon in a lower eukaryote, by analysis of gene banks. Cloned yeast genes have been used successfully to identify diatom genes of similar function and at least one yeast mutation leu 2-- has been complemented using cloned diatom DNA sequences. Background in molecular biology. Proficiency in recombinant DNA techniques: cDNA cloning, analysis of gene banks, vector construction, Southern and Northern hybridization, transformation, analysis of regulatory sequences, DNA sequencing. Salary starting at $25,332 to $27,624, depending on qualification. Send detailed curriculum vitae and three names for reference to: Dr. B.E. Volcani Scripps Institution of Oceanography University of California La Jolla, CA 92093; tel. (619) 534-2194. Applications will be accepted until positions are filled. An Equal Opportunity/Affirmative Action Employer.

+Lp t% a e I’NI\‘FRSITi A ‘AZ-1 J

Vertebrate Developmental Biologist Yale University Ikpartment of I(iology wittie to appoint a Vertebrate lkvctop- mental liiologist at thr A55istarit Profes- sorrhip I~el. ‘l‘he succ~s~fiil candidate shouJci carry on iI vigorous, independent research progr;tm, supervise the rcscarcti of graduntc 5tucients and postdoctoral feltowc, and contrikxrtc to t indergraduatc teaching.

Send curriculum vitae, description of research interests, and tl-ic name5 and nddrcsse\ of threr referee by March 1, 1985) to: (:hairman, Ikpartment of IQol- ogy, Yale Ifnivcrsity, I’.(). Box 666, New Hnvcn C’I‘ 065 1 1 ), I.

Yale University is an Affirmative Action/Equal Opportunity Employer.

Assistant Professor Pharmacology/Toxicology University of Kansas

The Department of Pharmacology & Toxicology at the University of Kansas, Lawrence, has an expanding program in membrane receptor biochemistry and pharmacology and is seeking a new faculty member with research interests and expertise in this area. Appointment will be at the assistant professor level in a tenure track position. Salary range: $30-36,000. We are looking for an individual with training and experience in the areas of membrane receptor isolation and reconstitution, molecular biology of receptor/ion channels, or membrane protein biochemistry and biophysics. Strong collaborations of departmental faculty with researchers in the departments of biochemistry, medicinal and pharmaceutical chemistry, microbiology, physiology/cell biology, and chemistry are ongoing. Candidates should hold the Ph.D. or M.D. degree and have a min imum of two years postdoctoral experience. All faculty are expected to establish a strong research program and participate in the teaching of graduate students in the department and of undergraduates in the School of Pharmacy. Send curriculum vitae, statement of research interests, and names of at least three references to:

Dr. Elias K. Michaelis, Chairman Department of Pharmacology/Toxicology University of Kansas Lawrence, KS 66045.

Applications must be postmarked by January 31, 1989.

Equal Employment Opporiunity/AfrTrmative Action Employer. Women and minority groups are encouraged to apply.

cell, Vol. 56, No. 1, January 13, I 989

Postdoctoral Position Genetics/Fluorescence Spectroscopy Carnegie Mellon University

A postdoctoral position is available immediately to study vacuolar function in Saccharomyces cerevisiae. The project will involve a unique combination of genetic and fluorescence approaches (using the excellent facilities of the Center for Fluorescence Research in Biomedical Sciences) to investigate the control of vacuolar pH. The position will be under the joint direction of Drs. Elizabeth W. Jones and Robert F. Murphy, and, through interactions with their research groups, will provide training in both the genetics of the yeast vacuole and the cell biology of endocytosis in mammalian cells. Experience in either molecular genetics or quantitative fluorescence methods is required. Send curriculum vitae and names and addresses of three referees to: Dr. Elizabeth W. Jones, Department of Biological Sciences, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213. Carnegie Mellon University is an Equal Opportunity/ Affirmative Action Employer.

Cel I...

lnforma five

lnfluen tial

Indispensable.

I Molecular Biologist The Department of Biomedical Research and the Division of Cardiology at St Elizabeth’s Hospital of Boston, Tufts University School of Medicine. is seeking 2 full-time stafF members with expertise in molecular biology The applicant must have established research productivity Both Ph D and M D candidates are eligible For M D candidates, opportunities are available to participate in patient care and teaching. In addition to development of his or her own research area. the applicant will have the opportunity to i participate in interdivisional collaborative studies as well as in a postgraduate research training program. Academic ‘; appointment is at the level of Assistant or Associate Professor, depending on qualifications.

The Department of Biomedical Research is currently I comprised of basic and clinical scientists with expertise in ‘j pathology, physiology, biochemistry cellular and 1

molecular biology, with primary areas of interest in cell : ‘j : membranes endothelium and vascular smooth muscle. .j

Up to 1,600 square feet of laboratory and office space in ,i newly constructed research laboratories as well as seed .‘.: funds for further research development are available

Applicants should send their C.V., summary of their : .‘,:. academic goals and representative reprints Lo Jeffrey t

M. Isner. M.D., Director, Cardiovascular Research, :i St. Elizabeth’s Hospital of Boston, Tufts University

.: ‘,’

’ .;,, School oFMedicine, 736 Cambridge Street. Boston, cnc .I.:;

Postdoctoral Positions

New England Regional Primate Research Center

Harvard Medical School

Postdoctoral positions are available in the following areas: 1) Molecular biology of simian immunodeficiency virus (SIV); 2) Genetic diversity of SIV; 3) Molecular basis for the oncogenicity of herpesvirus saimiri (HVS). For SIV, see Ann. Rev. Micro. 42: 607, 1988 and J. Viral. Nov. and Dec. 1988. For HVS, see J. Virol. 57: 701, 1986; Science 239: 1145, 1988; Cell 54: 599, 1988. The location is 25 miles west of Boston in a wooded, rural setting.

Send curriculum vitae and names of three references to:

Dr. Ronald C. Desrosiers Harvard Medical School New England Regional Primate Research Center One Pine Hill Drive Southboro, MA 01772.


L

A

Faculty Position in Cellular Biology Bates College

Bates College, a selective, science active, liberal arts college with 1500 undergraduates is seeking applicants for a tenure track position in cell biology at the assistant professor level for fall 1989. Responsibilities include teaching a required course in cellular and molecular biology and advanced undergraduate course: at the cellular level which could include microbiology, immunology, virology, and/or membrane biology. Establishment of a vigorous research program involving undergraduates is expected. A Ph.D. is required and postdoctoral experience is preferred. By February 1, 1989, send curriculum vitae, a statement of teaching and research interests, graduate transcripts, and the names of three references to: Dr. Joseph Pelliccia Cell Biology Search Department of Biology Bates College Lewiston, Maine 04240. Bates College is an Equal Opportunity Employer and encourages applications from women and minority candidates.

POSTDOCTORAL POSITION

THE DANA-FARBER CANCER INSTITUTE

The Dana-Farber Cancer Institute is seeking to fill one research position at the postdoctoral level to study gene coding for T-cell products that regulate the immune response in collaboration with other laboratory investigators. A joint appointment will be held in an appropriate department of Harvard Med ical School. Send curriculum vitae and names of two references to Dr. Harvey Cantor.

44 Binney Street, Boston, MA 02115 An 4ff1rmar1ve Actmn hployx

Postdoctoral Research Position Molecular/Cellular Biology

Harvard Medical School Massachusetts General Hospital

A fully funded postdoctoral research position is immediately available for a molecular/cellular biologist in a multidisciplinary group. The research project includes study of hormone receptor expression during hematopoietic stem cell differentiation, and identification and molecular cloning of receptors regulating skeletal tissue cells. Preference will be given to those with experience in application of recombinant DNA techniques.

Candidate should forward curriculum vitae and three letters of reference to:

Dr. Steven l?. Goldring Arthritis Unit Massachusetts General Hospital Boston, MA 02114.

Postdoctoral Position

Molecular and Cellular Biology Jewish Hospital at Washington

University Medical Center

A position is available for Ph.D. to study the gene expression of tissue inhibitor of metalloproteinases (TIMP) in fibroblasts and during cellular differentiation of mononuclear phagocytes. Studies will also involve mechanisms of coordinate regulation of TIMP with various metalloproteinases utilizing state-of-the-art molecular and cell biologic approaches. The position allows for collaborative research with other faculty members studying the biology of extracellular matrix,

Applicants should send their curriculum vitae and names of references to:

Dr. Howard G. Welgus Department of Medicine Jewish Hospital at Washington

University Medical Center St. Louis, M O 63110.

Cell, Vol. 56. No. 1, January 13. 1989

Postdoctoral Positions

The Institute of Cancer Research Section of Cell and Molecular Biology

Two postdoctoral positions are available in the Cncogene Team (Group Leaders: A. Hall and C. J. Marshall) to study the function of ras and ras related proteins in cell division and transformation. A wide variety of techniques in cell biology, molecular genetics, and biochemistry are being used to address these questions. The Chester Beatty laboratories provide excellent facilities for research in cell and molecular biology. Salary in the range of f 13,130 to f 15,950 inclusive. Applicants are advised that smoking is prohibited in the majority of the Institute’s premises. Informal enquiries may be addressed to Dr. A Hall or Dr. C. J. Marshall on 01-352-8133 ext. 5178. Applications should be sent in duplicate with the names and addresses of two referees to the: Personnel Officer, The Institute of Cancer Research, 17A Onslow Gardens, London SW7 3AL, UK, quoting reference number 12.88.S.C.58.

Research Associate and

Post Doctoral Fe llow (Two Positions)

Quantification o f Recombinant DNA methods. Salar quali [cations. Send inquiries r

commensurate w ith

and C.V. to: O ffice o f Person- nel, Code 2840, Boston Univer- sity Med ical Cam us, 80 East ~;,ngord Street, k oston, MA

. An Affirmative Action/Equal Opportunity Employer

PROFESSOR AND CHAIRPERSON

DEPARTMENT OF ANATOMY

UMDNJ-New Jersey Medical School invites nominat ions and applications for the position of Chairperson and Professor of the Department of Anatomy. Candidates must have a strong record of achievement in research and teaching of Anatomy and/or Cell Biology. The successful candidate will have the opportunity to build a strong, contemporary department with approximately 20 faculty members who will be responsible for teaching medical, dental, and graduate students, as well as conduct ing research programs in cell biology. The institution is prepared to commit appropriate resources for new pro- grammatic development. Send curriculum vitae or nominations to: George W. Machiedo, M.D., Chairman, Anatomy Search Committee, c/o L inda C. Reich, NJMS-Off ice of the Dean, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, MSB-Level 8, Room 502, (C), 185 South Orange Avenue, Newark, NJ 07103-2757.

The UMDNJ is an Affirmative Action/ Equal Employment Opportunity Employer M/F/H/V

Graduate Fellowships M icrobiology and Molecular Genetics

Department of M icrobiology University of Vermont

The Department of Microbiology at the University of Vermont invites applications from persons interested in a career in molecular biology. Current research opportunities include study of: the enzymology and regulation of cellular DNA repair processes: self-splicing mechanisms of RNA; structure and function of yeast chromatin; cloning and regulation of yeast ras/rho homologs; cloning and regulation of Schizophyl lum mating type genes; molecular mechanisms of bacterial adhesion; methyl-directed regulation of mammal ian transcription; RNA polymerase II/DNA interactions in eukaryotic cells; initiation and control of the carcino- genic state; and receptor mediated endocytosis and intracellular processing of protein toxins and viruses by cultured mammal ian cells. Tuition remission plus current stipend of $10,130 per year. For information write: Dr. Thomas J. Moehring, Department of Microbiology The University of Vermont, Given Building, Burlington, VT 05405.

Documents

Position available