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Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Polypeptide Chain Synthesis: A Paper Simulation Actitivy

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Page 1: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Page 2: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Proteins

Are organic polymers.◦Polymers are composed of monomers.

A monomer is a repeating structural unit

What is the repeating structural unit for a protein?

The amino acid

Page 3: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Basic Amino Acid Structure

Amino group R group Carboxyl group

Page 4: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

The Twenty Amino Acids with the R group of each highlighted

Page 5: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Polypeptide Synthesis

Involves two amino acids.Involves a dehydration synthesis.Involves a chemical reaction that occurs

between two specific areas of the amino acid.

Requires an –OH group and an –H from another –OH group

Page 6: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Think about these questions:

1. What is a polypeptide chain?2. What two functional groups are involved

in polypeptide synthesis?3. How can water form during the synthesis

of a polypeptide chain?

Page 7: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Is this a complete protein? No

Are organic polymers composed of monomers called amino acids. How many amino acids are in this chain?

Strands of amino acids are called polypeptide chains. Where are the peptide bonds?

Proteins are many chained structures.

Page 8: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Amino Acids Polypeptide Chain

Protein with twoPolypeptide chains

The complete protein is the picture with two polypeptide chains.

Page 9: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

What determines a specific protein?

The sequence of amino acids determines the specific protein

Question 10 on the lab wants you to write the sequence of amino acids from the paper chain

Phe-met-tryp-ala

Use the (4) amino acids to make a protein

Tryp–phe–ala-met

Make another one:Phe-tryp-met-ala

Page 10: Polypeptide Chain Synthesis: A Paper Simulation Actitivy

Functions of Proteins

Video for Protein Function